Chapter 5Chapter 5

Neurochemistry and Neurochemistry and PsychopharmacologyPsychopharmacology

Clinical NeuroscienceClinical Neuroscience by Kelly Lambert and Craig Howard Kinsleyby Kelly Lambert and Craig Howard Kinsley

NeurochemicalsNeurochemicals

Small-Molecule NeurotransmittersSmall-Molecule Neurotransmitters– AcetylcholineAcetylcholine– CatecholaminesCatecholamines– SerotoninSerotonin

Neurochemicals Neurochemicals (cont.)(cont.)

Amino Acid TransmittersAmino Acid Transmitters– Excitatory Amino AcidExcitatory Amino Acid– Inhibitory Amino AcidsInhibitory Amino Acids

Neurochemicals Neurochemicals (cont.)(cont.)

Neuropeptides and NeurohormonesNeuropeptides and Neurohormones– Endogenous OpioidsEndogenous Opioids– OxytocinOxytocin– VasopressinVasopressin

Neurochemistry of the Neurochemistry of the Stress ResponseStress Response

Autonomic Stress ResponseAutonomic Stress Response Hypothalamic-Pituitary-Adrenal Axis Hypothalamic-Pituitary-Adrenal Axis

ResponseResponse

Neurochemistry of the Stress Response Neurochemistry of the Stress Response (cont.)(cont.)

Other Brain Areas Involved in the Stress Other Brain Areas Involved in the Stress ResponseResponse– HippocampusHippocampus– AmygdalaAmygdala– Locus coeruleusLocus coeruleus

Foundations of Foundations of PsychopharmacologyPsychopharmacology

SummarySummary