1. recognizing dna for therapy and diagnostics . Andrey Golovin
June 2, 2015 AptaNova LLC
2. antibodies .
3. therapeutic antibodies Antibody market will reach $60-80 bln
at 2018 Russian market presented by import for 90% Drugs on market:
Avastin, Rituxan, Herceptin, Mylotarg, Bexxar, Benlysta ... ... ..
2008 . 2010 . 2012 . 2018 . 50 . 100 . year . Market,$bln 2
4. antibodies disadvantages immune response biogenic origin non
unied synthesis delivery action is not regulated (antidote is
unavailable) 3
5. aptamers .
6. aptamer . Aptamers are articial molecules of single-stranded
DNA molecule Aptamers binds protein target with non-covalent bonds
on base of surface complementarity. low immune response unied
chemical synthesis action is regulated (antidote is available)
sensor element 5