ISSN 0036-807519 JULY 1996VOLUME 273NUMBER 5273 S
AMERICANAssoCIATION FORTHEADVANCEMENT OFSCIENCE
A
* <e*
wfAff
307 -Atoms at the quantumedge
335 -wSimulating planetaryatmospheres
AAAS BoardRita R. ColwellRetiring President, Chairman
Jane LubchencoPresident
Mildred S. DresselhausPresident-elect
NEWS & COMMENTBiotech Finds a Growth Industry
AIDS Conference: Chemokines ShareCenter Stage With Drug TherapiesShooting for the Moon With Drugs
1997 Budget: Congress Targets Fusion,Favors NIH
Electronic Publishing: APS StartsElectronic Preprint Service
German Research Budget: Less Money,But Much Needed Reform
Xenotransplants: IOM Backs CautiousExperimentation
Particle Physics: Upgraded LEPBags First W Pairs
300
302
302
303
304
305
305
306
RESEARCH NEWSGiant Atoms Cast Long Shadow
Developmental Biology: Receptor forVital Protein Finally Found
307
309
THIS WEEK IN SCIENCE
EDITORIALRoads Not Taken, YetR. Roy
287
291
LETTERS 293Acid Rain Revisited?: C. R. Frink; J. W. Kirchner;G. E. Likens, C. T. Driscoll, D. C. Buso * Herbivoryin Soft Corals: Correction: K. Fabricius, Y. Benayahu,G. Yahel, A. Genine Diffusion to a Different Drum-mer: M. F. Schumaker * Extinction Rates: J. L. Simon;S. L. Pimm, J. L. Gittleman, G. J. Russell, T. M. Brooks
SCIENCESCOPE
of
299
Plant Biochemistry: Mutant rAlga Blurs Classic Pictureof Photosynthesis
Galileo Finds Mysterious MagneticField at Ganymede
Materials Science: Throwing-orMolding-a Curve Into Nanofabrication
RANDOM SAMPLES 313Sex and Olfaction * Berkeley Chancellor Plansto Move On * Invulnerable Vole Found at Cher-nobyl * Making Molds for Plastic Antibodies *
Harvard and China Probe Disease Genes * KobeEarthquake Continues to Rattle Walls * "Sociobi-ology" to History's Dustbin?
BOOK REVIEWS 316Creative Couples in the Sciences, reviewed by R. L.Sime * Genomic Imprinting, C. Sapienza * Vignettes* Books Received
375
DirectorsSheila JasanoffWilliam A. Lester Jr.Simon A. LevinMarcia C. LinnMichael J. NovacekAnna C. RooseveltJean E. TaylorNancy S. Wexler
William T. GoldenTreasurer
Richard S. NicholsonExecutive Officer
* SCIENCE (ISSN 0036-8075) Is published weekly on Friday, except the last week InDecember, by the American Association for the Advancement of Science, 1200 New YorkAvenue, NW, Washington, DC 20005. Periodicals Mail postage (publication No. 484460) paid atWashington, DC, and additional mailing offices. Copyright 1996 by the American Association forthe Advancement of Science. The title SCIENCE is a registered trademark of the AAAS. Domesticindividual membership and subscription (51 issues): $102 ($55 allocated to subscription). Domesticinstitutional subscription (51 issues): $250. Foreign postage extra: Mexico, Caribbean (surface mail)$55; other countries (air assist delivery) $90. First class, airmail, student, and emeritus rates onrequest. Canadian rates with GST available upon request, GST #1 254 88122. Printed In the U.S.A.
310
311
312
POLICY FORUM
Psychiatric Drug Developmentin JapanD. Berger and I. Fukunishi
318
PERSPECTIVESAtmospheric Dynamics on theOuter PlanetsP. J. Gierasch
Cuprates Fall into a GapN. P. Ong
Mechanosensation and theDEG/ENaC Ion ChannelsD. P. Corey and J. Garcia-Afioveros
V 320
r 321
0 323
SCIENCE * VOL. 273 * 19 JULY 1996
DEPARTMENTS
PRODUCTS & MATERIALS
IN QMOAM",NM
IMINSM
284
on April 13, 2021
http://science.sciencem
ag.org/D
ownloaded from
Endocytic compartment (-600 nanometers in diameter) ofa human mononuclear phagocyte revealed by electronmicroscopy of thin cryosections. Major histocompatibilitycomplex (MHC) class 11 molecules accumulate in thesemultilaminar compartments, which may be the major sites
RESEARCH ARTICLE
Excitation Gap in the Normal State r 325of Underdoped Bi,SrnCaCu,O5,6A. G. Loeser, Z.-X. Shen, D. S. Dessalu, D. S.M irshall, C. H. Pairk, P'. Fournier, A. Kapitulnik
REPORTS
Role of Lipid Polymorphism in 330Pulmonary SurfactantW. R. Perkins, R. B. DaIuse, R. A. Parente, S.R. Minchev, K. (C. NeuTman, S. M. Gruner, T.F. Taraschi, A. S. Janftd
Hydrogen-Bond Breaking and ProtonExchange in Collisions of Gaseous FormicAcid with Liquid Sulfuric Acid
3. K. Klassen and C. NI. Nathanson
The Morphogenesis of Bands andZonal Winds in the Atmospheres onthe Giant Outer Planets
J. Y.-K. Cho and L. NM. Polvani
CCOVER
333
r 335
A Magnetic Signature at lo: Initial 337Report from the Galileo Magnetometer
NX. C. Kivelson, K. K. KhuLrana, R. J. Walker,(C. T. RuLssell, J. A. L,inker, D. J. Southwood, C.POaIonskevI
Detection of Ozone on Ganymede 341K. S. Noll, R. E. Johnlson, A. L. Lane, D. L.Po(milngLe, H. A. Weaver
Self-Assembled Smectic Phases in 343Rod-Coil Block Copolymers
J. T. Chen, E. L. Thiomams, (C. K. Oher, G.-P. Mao
Complex Optical Surfaces Formed by 347Replica Molding Against Elastomeric MastersY. Xia, E. Kimn, X.-M. Zhao, J. A. Rogers, M.Prentiss, C. M. Whitesides
Cytoplasmic Tail-I)ependent 349Localization of CDlb Antigen-PresentingMolecules to MIICsM. Sugita, R. M. Jackiman, E. van Ponselaar, S.M. Behar, R. A. Rogers, P. J. Peters, M. B.Breinner, S. A. Porcelli
where endocytosed protein antigens are encountered.CD1 b (smaller, black-stained dots), a non-MHC-encodedmolecule that presents bacterial lipid antigens to T cells,also localizes to these compartments. See page 349. [Image:P. J. Peters, E. van Donselaar, M. Sugita, and S. A. Porcelli]
352
367Bewarefeeding fleas
370Peptide signals in plants
Immunostimulatory DNA SequencesNecessary for Effective IntradermalGene ImmunizationY. Sato, M. Roman, H. Tighe, D. Lee, M. Corr,M.-D. Nguyen, G. J. Silverman, M. Lotz, D. A.Carson, E. Raz
The Secreted Product of XenopusGene lunatic Fringe, a VertebrateSignaling Molecule
J. Y. Wu, L. Wen, W.-J. Zhang, Y. Rao
Resistance to Apoptosis Conferredby Cdk Inhibitors During MyocyteDifferentiation
J. Wang and K. Walsh
Interaction Between a PutativeMechanosensory Membrane Channeland a Collagen
J. Liu, B. Schrank, R. H. Waterston
355
359
361
Oxygenic Photoautotrophic Growth 59 364Without Photosystem I
J. W. Lee, C. V. Tevault, T. G. Owens, E.Greenbaum
Role of the Yersinia pestis Hemin 367Storage (hms) Locus in the Transmissionof Plague by FleasB. J. Hinnebusch, R. D. Perry, T. G. Schwan
Modification of Phytohormone 370Response by a Peptide Encoded byENOD40 of Legumes and a NonlegumeK. van de Sande, K. Pawlowski, I. Czaja, U.Wieneke, J. Schell, J. Schmidt, R. Walden, M.Matvienko, J. Wellink, A. van Kammen, H.Franssen, T. Bisseling
r Indicates accompanying featureChange of address: allow 4 weeks, giving old and new addresses and 8-digit account number.Postmaster: Send change of address to Science, P.O. Box 1811, Danbury, CT 06813-1811.Single copy sales: $7.00 per issue prepaid includes surface postage; bulk rates on request.Authorization to photocopy material for internal or personal use under circumstances not fallingwithin the fair use provisions of the Copyright Act is granted by AAAS to libraries and other usersregistered with the Copyright Clearance Center (CCC) Transactional Reporting Service, providedthat $4.00 per article is paid directly to CCC, 222 Rosewood Drive, Danvers, MA 01923. Theidentification code for Science is 0036-8075/83 $4.00. Science is indexed in the Reader's Guide toPeriodical Literature and in several specialized indexes.
On the Web
SCIENCE * VOL. 273 * 19 JULY 1996
http://www.sciencemag.org/285
on April 13, 2021
http://science.sciencem
ag.org/D
ownloaded from
273 (5273)
(5273), 287-376.273Science
ARTICLE TOOLS http://science.sciencemag.org/content/273/5273
PERMISSIONS http://www.sciencemag.org/help/reprints-and-permissions
Terms of ServiceUse of this article is subject to the
is a registered trademark of AAAS.ScienceScience, 1200 New York Avenue NW, Washington, DC 20005. The title (print ISSN 0036-8075; online ISSN 1095-9203) is published by the American Association for the Advancement ofScience
Science. No claim to original U.S. Government Works.Copyright © 1996 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of
on April 13, 2021
http://science.sciencem
ag.org/D
ownloaded from
Top Related