A journey of medical disruption
CMO John R Zibert, [email protected]
DISRUPTIVE CONCEPTUALISATION DAY10.00-10.45 am, 20TH SEPTEMBER 2016, DTU
UBERWorld’s largest Taxi company
Owns NOTaxisairbnb
World’s largest Accomodation provider
Owns NOReal estate
How do you builddisruptive innovation in a pharma organisation?
- You do not…
- You build a new organisation which looks into doing things in a different way by:
- Recruiting people from other industries who might find novel solutions to common and / or complicated problems
- Solve issues in a different way through e.g. digital HealthCare
Introducing…
International setup with a flat structure
SF Hub (1p)
CA Toronto Hub (2p)
UK London Hub (4p)
FR Paris Hub (3p)
DK Copenhagen Hub (32p)
ES Copenhagen Hub (1p)
Solutions above LEO Pharma brands
Developing integrated care is a multi disciplinary approach which requires stepwise innovation, superior use of data and patient centricity
Towards Integrated Care
Education MentalHealth
Family
Fitness
HCP vs Pt
Diet & Nutrition
Fashion &Beauty
Reframing a problem, may be the solution...
1. Build new elevator
2. Make it faster
3. Ask people to take the stairs
Workshops
IDEAS Work processExperiment phase => BETA Launch
Pitch Rounds
100 Days
Hackerton
Ideas (Partners/Stakeholders/Patients)
Crowd Innovation
External Inspiration
Next Step to Decide
Spin out – Separate entity
LEO Pharma A/S
LEO Innovation Lab Service
Competition
Open Source Innovation
Way of Working Model (WoW model)
Back to idea generator
Pipeline from Aug 2015 to Sep 2016 Pipeline filled and multiple experiments in progress
1 2 3 4 5 6
Idea Explore Concept MVP 100 days build Experiment Launch
Imaging
KidsSynbiotics
+PsoAcademy
TestingWearables
Elly
Prediction&Behavioural
Change
Virtualrealitykids
Skintop
SmartTop
MyPso
QualityCare
Flaym
Uniqly
+ LEO innovation Lab ventures
Today, medicine is largely reactive.
It waits until a person is sick and then treats a disease, with varying levels of success.
The question is where is medicine going…
Future of medicine
Social Network
Revolution
Digital revolution
Systems medicine
1. Digital Revolution in HealthCare
Mobile health apps may help you
Most people think they are significantly healthier than they are
It is not all about big-data
If we track behavior we
MUST aim for a behavioral
change
Photographer LoboStudio Hamburg
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Social Media activity vs. GPS location
Physical activity (steps and GPS)(0, inactive; 10 very active)
Soci
al M
edia
Act
ivity
(0, i
nact
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10
very
act
ive)
Potential Measures:
- Passive data collection- GPS- Accelerometer- App Usage- Compass- Decibel Level- Gyroscope- IP Address / WIFI- Social media
activity- Social media
listening (psychometri)
- Active Data collection- Pulse and HR- Sleep- Wearables
3. Systems Medicine
P4 medicine is the clinical face of systems medicine
Its two major objectives are to 1) quantify wellness and 2) demystify disease, through:
- Predictive measures,
- Preventive initiatives,
- Personalized care
- Participatory engagement.
3. Social network revolution
Computers’ judgments of people’s personalities based on their digital footprints are more accurate and valid than judgments made by their close others or acquaintances (friends, family, spouse, colleagues, etc.)
Wu Youyou et al. PNAS 2015;112:1036-1040
What will make people take their medication (adherent)?
Digital Health solutions may improve adherence
Projects - KlikkitMake products intelligent to connect with online treatment planBy start-up Director Anne Fleischer
Projects - KlikkitVery positive response and strong proof of concept
“Klikkit made it more fun to use the
products.” “The buttons are helping me remember to usethe treatments —particularly while I’m awayfrom home and not in my normal routine.”
“It’s the insight you get over time that makes
Klikkit worth it.”
Projects - ImagineTrack your flare-up progress in detail
Projects - ImagineQuantifying and tracking progress that would otherwise be ignored
However we cannot solve all problems ourself…
Enables breakthroughs
TWO ONLINE CHALLENGES IN OCTOBER
LOOKING FOR BREAKTHROUGH TECHINCAL SOLUTIONS
1st Relief Itch
A technical breakthrough in relieving itch
US$ 50.000Go to www.leoinnovationlab.com
2nd Prediction
How to use predictive analytics to help take out the uncertainty from skin diseases
US$ 100.000Go to www.leoinnovationlab.com
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