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Used since ancient times
Opium
Medicinal properties
Painkiller
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Obtained from seedheads of the poppypapaver somniferum
Opium
Seed head of opium
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Seed heads are scored
Opium
Latex
Dried latex Opium
Seed head of opium
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Paracelsus
Opium
Opium extract in alcoho
Laudanum
Medicinal use
Major illegal producer Afghanistan
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Opium
Morphine
Active componentof opium
MorphineStill clinically usedas a painkiller
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Opium
Major legal producer Tasmania
Uses Gastrointestinal problems
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Opium
Samuel Taylor Coleridge
Xanadu
Samue
Colerid
Written under theinfluence of opium
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Opium
"This fragment with a good deal morerecoverable, composed, in a sort of Rebrought on by two grains of Opium takecheck a dysentery, at a Farm House betw
Porlock and Linton, a quarter of a mile Culbone Church, in the fall of the year, 17
Samuel Taylor Coleridge
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Opium
Still used in medicines
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Opium
Inspired composers
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Opium
SymphonieFantastique
Hector
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Opium
Inspired composers
Caused wars Two opium wars betwethe British and the Chin
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Battle of the Palikia
Second Opium Wa
Opium
Two opium warsbetween the Britishand the Chinese
1839-1842
1856-1860
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Opium
Inspired composers
Caused wars Two opium wars betwethe British and the Chin
Affected the Second World War
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Opium
Hermann Goering
Hermann G
Head of the Germanair force during WW2
Morphine addict
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Trio
Opium
Morphine
Heroin
Active ingredient in crude material
Crude material from plant
What is heroin?
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Semi-synthetic
Heroin
Invented by Bayer Co.
Diacetylmorphine
More potent than morphine
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Banned in many countries
Heroin
In a few countries May still be usedmedicinally
Doctor prescriptio
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Serial killer
Harold Shipman
Murdered old ladies
Administered lethal
doses of heroin
No investigationuntil he forged a will
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Diacetylmo
or diamorpMorphine
How heroin works
Acetic anhydride
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How heroin works
Heroin Impure
Diacetylmorphine / diamorphin
Acetic anhydride
Controlled in many Asian countries
Pure
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How heroin works
How does diamorphine work?
Why is it much more effective than morphin
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Diamorphi
Diamorphine / diamorphine
Morphine derivatization
Acetyl groups are rapidlymetabolized to morphine
Faster transportof the molecule
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Faster transport to the brain
Rapid metabolization to morphine
Higher concentration in a shorter time
Diamorphine not detected in blood / u
Diamorphine / diamorphine
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Etorpine
Very powerfultranquilizer
Morphine analogs
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Etorpine
Very powerfultranquilizer
Morphine analogs
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Heroin
Morphine
Codeine
Related compounds
Thebaine
Acetyl codein
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Heroin
Unrelated compounds Papaverine
Noscapine
Cutting agents Sugar
Caffeine
Barbiturates
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Heroin
GC or HPLC
Analysis of impurities
Show if two samples camefrom the same source
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