WYETH PHARMACEUTICALSMain Problems Top selling drugs are nearing their expiry patent

durations.Increasing competition in terms of pricing pressures.

Effects

• revenue shortfall

SOLUTION SUGGESTED To reduce operating expenses by 25% to

remain competitive in Pharmaceuticals industry.

HOW Process improvement with the help of

external advisory firms with more focus on cultural changes.

BARRIER Less coordination between sites and

between site and company.

Transformation Programs offered by External Advisory firmOperating system improvements through

lean & six sigma by eliminating waste, variability and inflexibilities from production systems.

Making improvements in management infrastructure-how the site was organized and managed.

Improving mindsets and behaviours of all employees through training, communication and incentives.

INTERNAL CHALLENGEs1. Leadership Coalition- To get the 12

most senior people in TO&PS to believe & allign with the management goal of 25% savings.

HOW Central Guiding principles to assist in

decision making and addressing internal challenges.

No compromise on customer service, coordinated approach, emphasis on employee engagement, sharing common processes.

Central Guiding PrinciplesNo compromise of expectation for customer

service, quality & compliance.Consistent and coordinated approach

across all sites.Fully integrated improvement across

functions and willingness to make fundamental, step change improvement in processes.

Explicit emphasis on engagement of all employees, and on capability building and changing mindsets and behaviours to ensure sustainability.

Central Guiding Principles..Sharing and development of best practices.Standardization of common processes

across all sites.Bias for action, tolerance for ambiguity and

willingness to make mid course correction.

2. Communication within sites HOW Bringing together managing directors and

quality managers from all sites. Employing mini transformation activities

across all sites Engagement of operators through cultural

changes with the concept of mindsets and behaviours.

3. Quality management concerns- Many Quality heads were skeptical of meeting the aspirations laid out by senior managers with the help of lean processes.