Worlds first accurate glaucoma screening algorithm - opti.de · PDF fileRetinaLyze System...
Transcript of Worlds first accurate glaucoma screening algorithm - opti.de · PDF fileRetinaLyze System...
RetinaLyze System Switzerland GmbH
Worlds first accurate glaucoma screening algorithm
Automated lesion detection software
Our current system
RetinaLyze, an automated screening tool for DR and AMD
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Online software, which screens automatically (not a diagnosis) and delivers easily understandable results
Cooperates with ophthalmologists by referring to an ophthalmologist for further examination, if needed
Results within 30 seconds
Seamless integration with fundus cameras
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Perimetry and OCT
Time consuming (SITA fast = 5-8 minutes)
Customer fatigue
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Expensive for screening purposes
How we normally assess the optic nerve disc
AAO guidelines:
• Generalized enlargement of the cup
• Focal enlargement of the cup
• Superficial splinter hemorrhage
• Loss of nerve fiber layer
• Translucency of the neuroretinal rim
• Development of vessel overpass
• Asymmetry of cupping between the patient’s eyes
• Peripapillary atrophy (beta zone)
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Comparision with the other methods
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RetinaLyze Glaucoma GDF
RetinaLyze Glaucoma VERT. C/D
RetinaLyze Glaucoma AREA C/D
New version
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New discriminant index between normality and glaucoma
New index has a sensitivity and specificity much higher than the previous one
7 different cameras
Superior to the results we have obtained with OCT in the same patient groups
From image to result in under 1 minute
Capture imageTransfer image to
RetinaLyzeInitiate analysis Get result
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0,9 billion diabetics
207.000
ophthalmologists
209.000
ophthalmologists
205000
207000
209000
211000
213000
215000
217000
219000
221000
223000
225000
2015 2025500
700
900
1100
1300
1500
1700
1900
No
. o
f D
iab
ete
s p
ati
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ts in
mill
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Gap in the no. of diabetics and ophthalmologists the next 10 years
Alle diabetes patients must be screened every year for DR. Ophthalmologists perform the screening today.
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Sources: International Council of Ophthalmology (ICOPH) - http://www.icoph.org/ and International Diabetes Federation (IDF) - http://www.diabetesatlas.org/
1,8 billion diabetics
Projected increases in AMD and Glaucoma cases
196000000 million
288000000 million
76000000 million
111800000 million
2020 2040
AMD
Glaukom
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Source: https://www.ncbi.nlm.nih.gov/pubmed/25104651 and https://www.ncbi.nlm.nih.gov/pubmed/24974815
Why should retail optometrists screen for eye diseases?
3 of the biggest causes for preventable blindness are DR, AMD and Glaucoma.
At least 90% of these incidents develop very slowly.
The patient will not notice any symptoms in the early stages.
The earlier the disease is caught, the more vision can be saved and the cheaper it is to
provide treatment.
Optometrists have the manpower and can provide accessibility for the clients!
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What is in it for the optometrist?
• Attraction of new customers with novel services (add-on for your eye-test), increasing
revenue
• Gain long-term relationships with your customers by making eye-health a part of your
business
• Remove focus from pricing and regain professional brand
• Annual screenings allows for more regular contact with existing customers, increasing
revenue
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How do I cooperate with the ophthalmologists?
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2. RetinaLyze-screening
RetinaLyze automatically screens the images and gives results for DR, AMD and/or
Glaucoma.
Red resultsCan be red results or patients with symptoms.
4. Local ophthalmologist diagnoses
If necessary, the operator refers the patient to the local ophthalmologist,
who diagnoses and treats the patient.
Green or yellow resultsPatient is invited for a screening again
withing 3-12 months.
1. Capture fundus images
An operator captures fundus images of their patients.
3. Tele-medicine assessment
An eye-specialist asseses the image online and gives the
operator guidelines for the next steps.
The advantages of this process
Helps ophthalmologists sort out people who don’t need their attention
Only patients with suspected eye conditions are assessed with telemedicine (cuts costs and doesn’t waste
anyone’s time)
Necessary information for the referral to the local ophthalmologist is checked via telemedicine before referral
The severity of the issue is assessed to make sure that no-one is rushed to the local ophthalmologist without
need.
Increases cooperation between ophthalmologist and optometrist.
Optometrists can get help and guidance immediately, if there is a pressing issue or doubt.
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Does this process actually work?
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Out of over 635.200 screenings we found 5.871 people with potential undiagnosed illnesses (an excerpt):
Total number of clients screened: 134.489
2.375 AMD 754 Diabetic Retinopathy1.013 Glaucoma 267 Pre-retinal Fibrosis191 Hemorrhages156 Chorioretinitis sequelae91 Arterial Hypertension63 Pseudoforamen
71 Suspected tumor9 Cataract41 Exudate51 Papilloedema37 Venous Thrombosis15 Artery embolism22 Oedema8 Amotio Retinae
A group of diseases which attack the eye’s optic nerve
There are several types of glaucoma
A liquid called aqueous humor is produced continuously in the
eye. If the liquid cannot escape again, the pressure builds and
damages the optic nerve
Symptoms develop over time or can be very acute
Often no symptoms in the beginning, but then often blurred or
decreased vision with halos
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In a healthy eye, excess fluid leaves the eye through the drainage angle, keeping pressure stable.
Diagnosis and treatment
Tension (IOP) and cup/disk ratio have been indicators when performing a screening
Visual Field Analysis, Cornea Thickness (CCT) measurement, Fundus images, Inspection of eye’s
drainage canal is necessary for diagnosis
Treatment options:
Medication, Laser surgery, Operating room surgery to relieve pressure
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