Williams Et Al 2000 OGM in MBCT

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    Journal of Abnormal Psychology Copyright 2000 by the American Psychological Association, Inc.

    2000, Vol. 109, No. 1, 150-155 0021-843X/00/ 5,00 DOI: 10.1037//0021-843X.109.1.150

    M indfulness Based Co gnitive Therapy Re duces Overgeneral

    Autobiographical M em ory in Form erly D epressed Patients

    J M a r k G

    Williams

    U n i v e r s i t y o f W a l e s, B a n g o r

    John D Teasdale

    M e d i c a l R e s e a r c h C o u n c i l

    Zindel V Segal

    C l a r k e I n s t i t u t e o f P s y c h i a t r y

    J u d i t h S o u l s b y

    U n i v e r s i t y o f W a l e s , B a n g o r

    Previous research on depressed and suicidal patients and those with posttraumatic stress disorder has

    shown that patients' mem ory for the past is overgeneral (i.e., patients retrieve generic sum maries of past

    events rather than specific events). This study investigated whether autobiographical memory could be

    affected by psychological treatment. Recovered depressed patients were randomly allocated to receive

    either treatment as usual o r treatment designed to reduce risk of relapse. W hereas control patients showed

    no change in specificity of memories recalled in response to cue words, the treatment group showed a

    significantly reduced number of generic memories. Although such a memory deficit may arise from

    long-standing tendencies to encode and retrieve events generically, such a style is open to modification.

    W h e n p e o p l e t r y t o r e t r i ev e s p e c i f i c e v e n t s f r o m t h e i r p a st , t h e y

    f i r s t a c c e s s h ighe r l e ve l , ge ne ra l de sc r ip t ions , us ing the se a s in te r -

    m e d i a t e s t e p s t o d e r i v e p o i n t e r s t o t h e l o w e r l e v e l , s p e c i f i c e v e n t

    re pre se nta t io ns (Re i se r , B la c k , & Abe lson , 1985; s e e Rub in , 1996,

    f o r a r e v i e w ) . C h a r a c t e r i z i n g a u t o b i o g r a p h i c a l m e m o r y a s a h i e r -

    a r c h y , w i t h m o r e g e n e r a l i n f o r m a t i o n h i g h e r i n t h e h i e r a rc h y , a n d

    m o r e d e t a i le d , s p e c i f i c i n f o r m a t i o n l o w e r i n t h e h i e ra r c h y , p e o p l e

    a r e n o r m a l l y a b l e t o m o v e f l u e n t l y th r o u g h t h e h i e r a r c h y , s e l e c ti n g

    t h e l e v e l o f s p e c i f i c i ty n e c e s s a r y t o r e s p o n d a p p r o p r i a t e l y t o t h e

    g i v e n c o n t e x t.

    H o w e v e r , s e v e r a l r e c e n t s t u d i e s s u g g e s t t h a t d e p r e s s e d p a t i e n ts

    h a v e c o n s i d e r a b l e d i f f i c u l ti e s m o v i n g f l u e n t l y t h r o u g h t h e m e m o r y

    h i e r a rc h y . T h e i r m e m o r y a p p e a r s t o a b o r t t h e s e a r c h f o r a s p e c i f ic

    e v e n t p r e m a t u r e l y , w h e n o n l y t h e g e n e r a l d e s c r i p t i o n s t a g e h a s

    b e e n r e a c h e d . F o r e x a m p l e , i n r e s p o n s e t o a w o r d c u e s u c h a s

    kindness

    s u c h a d e p r e s s e d p a t i e n t m a y r e s p o n d , M y g r a n d m o t h e r

    w a s a l w a y s k i n d t o m e . S h e u s e d t o t a k e m e o u t w h e n m y f a t h e r

    g o t c r o s s . I n th i s e x a m p l e , t h e p a t i e n t is re s p o n d i n g w i t h a

    s u m m a r y d e s c r i p ti o n , a c a t e g o r y o f e v e n t s , r a t h er t h a n r e t r i e v i n g a

    s p e c i f i c e v e n t t h a t h a p p e n e d a t a p a r t i c u l a r p l a c e a n d t i m e ( s e e

    Wi l l i a m s , 1996, for a r e v ie w) .

    J. Mark G. W illiams and Judith Soulsby, Institute of Medical and Social

    Care Research, University of Wales, Bangor; John D. Teasdale, Cognition

    and Brain Sciences Unit, Medical Research Council, Cambridge, England;

    Zindel V. S egal, Clarke Institute of Psychiatry, Toronto, O ntario, Canada.

    This research was funded by grants from the National Health Service

    Wales O ffice of Research and Developm ent and fro m the National Institute

    of Mental Health (Grant 53457). We thank Jess Eade, Valerie Ridgeway,

    Susan Williams, Mark Lau, Neil Rector, Jon Kabat-Zinn, Ferris Ur-

    banowsky, and Saki Santorelli for their help.

    Correspondence concerning this article should be addressed to J. Mark

    G. Williams, Institute of Medical and S ocial Care Research, University of

    Wales, Bangor, LL57 2U W, United Kingd om. Electronic mail may be sent

    to j.m.g.williams @ bangor.ac.uk.

    150

    O r i g i n a l l y d e s c r i b e d i n s u i c i d a l p a t ie n t s ( W i l l i a m s & B r o a d b e n t ,

    1 9 8 6 ; W i l l i a m s & D r i t s c h e l , 1 9 8 8 ) , s u b s e q u e n t r e s e a r c h f o u n d

    o v e r g e n e r a l m e m o r y t o b e a c h a r a c t e r i s ti c o f d e p r e s s i o n ( G o d d a r d ,

    D r i t s c h e l , & B u r t o n , 1 9 9 6 ; K u y k e n & B r e w i n , 1 9 9 5 ; K u y k e n &

    D a l g l e i s h , 1 9 9 5 ; M o o r e , W a t t s , & W i l l i a m s , 1 9 8 8 ; P u f f e t , J e h i n -

    M a r c h o t , T i m s i t - B e r t h i e r , & T i m s i t , 1 9 9 1 ; W i l l i a m s & S c o t t ,

    1 9 8 8 ) a n d p o s t t r a u m a t i c s t r e ss d i s o r d e r ( M c N a l l y , L a s k o , M a c k l i n ,

    & Pi tm a n, 1995; Mc Na l ly , L i t z , Pra s sa s , Shin , & We a the r s , 1994) .

    K u y k e n a n d B r e w i n ( 1 9 9 5 ) f o u n d t h a t o v e r g e n e r a l i t y i n m e m -

    o r y i n d e p r e ss e d w o m e n w a s a s s o c ia t e d w i t h a h i g h e r n u m b e r o f

    p r e v i o u s s u i c i d e a t t em p t s a n d e p i s o d e s o f d e p r e s s io n . I n a d d i t i o n ,

    o v e r g e n e r a l m e m o r y w a s a s s o c i a t e d w i t h g r e a t e r f r e q u e n c y o f

    i n t r u s io n s o f p a s t s t r es s f u l e v e n t s s u c h a s p h y s i c a l a n d s e x u a l

    a b u s e , s u g g e s t i n g e i t h e r t h a t t h e e f f o r t i n v o l v e d i n s u p p r e s s i n g o r

    a v o i d i n g u n p l e a s a n t m e m o r i e s d i s r u p t s t h e m e m o r y s e a r c h a t t h e

    p o i n t w h e r e i t m o v e s f r o m g e n e r a l d e s c r i p t i o n s t o s p e c i f i c e v e n t s

    o r t h a t s o m e i n d i v i d u a l s s t r a t e g i c a l l y a d o p t a n o v e r g e n e r a l r e -

    t r i e v a l s t y l e a s a m e t h o d f o r d e a l i n g w i t h p o t e n t i a l l y e m o t i o n a l

    m a t e r i a l . A l t h o u g h s u c h o v e r g e n e r a l r e t r i e v a l m a y t h u s a p p e a r t o

    h a v e a n a d a p t i v e , a f f e c t r e g u l a t i o n f u n c t i o n , i t h a s a l s o b e c o m e

    c l e a r th a t i t h as a n u m b e r o f m a l a d a p t i v e e f f e c t s . A l t h o u g h n o t a l l

    p a t i e n ts s h o w t h i s d e f i c i t t o t h e s a m e e x t e n t , p a t i e n t s w h o a r e m o r e

    o v e r g e n e r a l f o r n e g a t i v e e v e n t s i n t h e i r l i v e s ( a ) a r e a l s o m o r e

    o v e r g e n e r a l f o r p o s i t i v e an d n e u t r a l e v e n t s ( W i l l i a m s , 1 9 9 6 ) ; ( b)

    s h o w d e f i c i t s i n i n t e r p e r s o n a l p r o b l e m s o l v i n g ( E v a n s , W i l l i a m s ,

    O ' L o u g h l i n , & H o w e l l s , 1 9 9 2 ; G o d d a r d e t al . , 19 9 6 ; S i d l e y , W h i t -

    t a ke r , Ca la m , & W e l l s , 19 97) ; ( c ) f ind i t d i f f i c u l t to im a gine the

    f u t u r e i n a s p e c i f i c w a y a n d a r e m o r e h o p e l e s s ( W i l l i a m s , 1 9 9 7 ;

    W i l l i a m s e t a l . , 1 9 9 6 ) ; a n d ( d ) m a y t a k e l o n g e r t o r e c o v e r f r o m t h e

    di sorde r (Br i t f l e ba nk, Sc ot t , Wi l l i a m s , & Fe r r i e r , 1993; Ha rve y ,

    B r y a n t , & D a n g , 1 9 9 8 ; h o w e v e r , s e e B r e w i n , P h i l l i p s , C a r r o l l , &

    Ta ta , 1998, for a nonre pl ic a f ion) .

    I f t h is m e m o r y d e f i c i t h a s s u c h d e t r i m e n t a l e f f e c t s o n f u n c t i o n -

    i n g , c a n i t b e m o d i f i e d ? O n e p o s s i b i l i ty i s t h a t s u c h a d e f i c i t a ri s e s

    f r o m t h e s e v e r i t y o f m o o d d i s t u r b a n c e . I f so , th e n r e d u c i n g m o o d

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    SHORT REPORTS 151

    d i s t u r b a n c e w i l l r e d u c e t h e m e m o r y d e f i c i t . H o w e v e r , r e s e a r ch h a s

    s u g g e s t e d t h a t , u n l i k e m a n y c o g n i t i v e b i a s e s a s s o c i a te d w i t h e m o -

    t i o n a l d i s o r d e r s ( W i l l i a m s , W a t t s , M a c L e o d , & M a t h e w s , 1 9 9 7 ) ,

    t h e p h e n o m e n o n o f o v e r g e n e r a l r e c a l l i s n o t m o o d - s t a t e d e p e n d e n t .

    I n a c r o s s - s e c t i o n a l s t u d y , W i l l i a m s a n d D r i t s c h e l ( 1 9 8 8 ) t e s t e d a

    g r o u p o f p r e v i o u s l y s u i c i d a l p a t i e n t s w h o h a d t a k e n a d r u g o v e r -

    d o s e b e t w e e n 3 an d 1 4 m o n t h s b e f o r e a s s e ss m e n t . T h e y f o u n d t h a t

    e x p a t i e n t s d i d n o t d i f f e r s i g n i f i c a n t l y f r o m c u r r e n t p a t ie n t s i n h o w

    o v e r g e n e r a l t h e y w e r e i n t h e i r m e m o r i e s , b o t h o f t h e s e g r o u p s

    b e i n g s i g n i f i c a n t l y m o r e i m p a i r e d t h a n c o n t r o l s . I n a l o n g i t u d i n a l

    s t u d y , B r i t t l e b a n k e t a l . ( 1 9 9 3 ) t e s t e d d e p r e s s e d p a t i e n t s o n t h r e e

    o c c a s i o n s : o n a d m i s s i o n , 3 m o n t h s l a t e r, a n d 7 m o n t h s l a t e r. T h e r e

    w a s n o c h a n g e i n r e s p o n s e t o p o s i t i v e o r n e g a t i v e c u e s , e v e n i n

    t h o s e p a t i e n t s w h o s e m o o d i m p r o v e d c o n s i d e r a b l y . S i m i l a r l y ,

    K u y k e n a n d B r e w i n ( 1 9 9 5 ) f o u n d i n t h e i r s a m p l e o f d e p r e s s e d

    w o m e n t h a t th e c o r r e l a t io n b e t w e e n l e v e l o f c u r re n t d e p r e s s i o n

    ( m e a s u r e d w i t h t h e B e c k D e p r e s s i o n I n v e n t o r y ) a n d o v e r g e n e r a l

    m e m o r y w a s l o w an d n o n s i g n i fi c a n t, r( 5 4 ) = - 0 . 0 2 a n d - 0 . 0 6 f o r

    p o s i t i v e a n d n e g a t i v e c u e s , r e s p e c t i v e l y .

    T h e r e s u l t s f r o m o n l y o n e s t u d y h a v e s u g g e s t e d t h a t o v e r g e n -

    e r a l i t y m i g h t n o r m a l i z e o n r e c o v e r y . K u y k e n a n d D a l g l e i s h ( 1 9 9 5 )

    r e p l ic a t e d t h e o v e r g en e r a l m e m o r y p h e n o m e n o n i n a s a m p l e o f 3 3

    d e p r e s s e d p a t i e n t s c o m p a r e d w i t h 3 3 m a t c h e d c o n t r o l s . H o w e v e r ,

    t h e y n o t i c e d t h a t 1 4 o f t h e i r c o n t ro l s ( 4 2 % ) r e p o r t e d h a v i n g h a d

    o n e o r m o r e e p i s o d e s o f d e p r e s s i o n i n t h e p a s t. T h e r e m a i n d e r h a d

    n e v e r b e e n d e p r e s se d . I n a p o s t h o c a n a l y s is , t h e y c o m p a r e d t h e

    p r e v i o u s l y d e p r e s s e d w i t h t h e n e v e r d e p r e s s e d g r o u p , f i n d i n g n o

    d i f f e r e n c e b e t w e e n t h e m i n t h e i r t e n d e n c y t o r e t r i e v e g e n e r a l

    m e m o r i e s . A s t h e a u t h o r s s t a t e d , h o w e v e r , n o s t r o n g c o n c l u s i o n s

    c o u l d b e d r a w n f r o m t h i s a s p e c t o f t h e i r s t u d y . T h e r e w a s n o

    i n f o r m a t io n a b o u t h o w m a n y o f t h e p r e v io u s l y d e p r e ss e d g r o u p

    h a d r e c e i v e d p s y c h o t h e r a p y n o r a b o u t t h e n a t u r e o f t h e i r p r e v i o u s

    d e p r e s s i o n . F u r t h e r m o r e , t h e d a t a w a s c r o s s - s e c t i o n a l , a n d a n

    e x p l a n a t i o n i n t e r m s o f a l o n g - t e r m t r a i t r e m a i n s p o s s i b l e : S u b -

    g r o u p s o f d e p r e s s e d p a t i e n t s w h o h a v e s e v e r e r e t r i e v a l p r o b l e m s

    a n d a r e l e s s l i k e l y t o r e c o v e r ( B r i t t le b a n k e t a l ., 1 9 9 3 ) w i l l b e l e s s

    l i k e l y t o a p p e a r i n t h e r e c o v e r e d g r o u p i n s u c h a s t u d y . O t h e r

    s u b g r o u p s o f d e p r e s s e d p a t ie n t s w h o h a v e r e l a t i v e l y s p a r e d m e m -

    o r y a r e m o r e l i k e l y t o r e c o v e r a n d t o b e p r e s e n t i n t h e r e c o v e r e d

    s a m p l e .

    O n t h e b a s i s o f t h e s e s t u d i e s , p r e v i o u s i n v e s t i g a t o r s h a v e c o n -

    c l u d e d t h a t o v e r g e n e r a l m e m o r y i s a c o g n i t i v e s t y l e , a l o n g - t e r m ,

    t r a i t - l i k e p h e n o m e n o n . F o r e x a m p l e , W i l l i a m s ' s r e v i e w ( 1 9 9 6 )

    s u g g e s t e d t h a t s u c h a m e m o r y s t y l e s t a r t s e a r l y i n d e v e l o p m e n t ,

    r e n d e r i n g p e o p l e v u l n e r a b l e t o d e p r e s s i v e b r e a k d o w n a n d t o p o s t -

    t r a u m a t i c s t r e s s d i s o r d e r ( P T S D ) r e a c t i o n s i n t h e f a c e o f t r a u m a ,

    a g r e e i n g w i t h B r i t t l e b a n k e t a l . ' s ( 1 9 9 3 ) c o n c l u s i o n t h a t o v e r g e n -

    e r a l m e m o r y c o n s t i t u t e s a t r a it m a r k e r o f v u l n e r a b i l i t y ( p . 1 21 ).

    T h e i m p l i c a t i o n o f t h e s e c o n c l u s i o n s a p p e a r e d t o b e t h a t s u c h a

    c o g n i t i v e s t y l e w o u l d b e r e l a t i v e l y r e s i s t a n t t o c h a n g e .

    T h i s c o n c l u s i o n w a s b a s e d o n t h e f i n d i n g t h a t o v e r g e n e r a l

    m e m o r y w a s n o t m o o d - s t a t e d e p e n d e n t , s o t h at r e d u c i n g l e v e l s o f

    e m o t i o n a l d i s tu r b a n c e w o u l d b e u n l i k e l y t o c h a n g e i t . H o w e v e r , n o

    s t u d y h a d e x a m i n e d w h e t h e r o v e r g e n e r a l m e m o r y c o u l d b e

    c h a n g e d b y t r e a t m e n t . A n o p p o r t u n i t y t o e x a m i n e t h e s e i s s u e s

    a r o s e d u r i n g t h e c o u r s e o f a r a n d o m i z e d c o n t r o l l e d t ri a l o f

    m i n d f u l n e s s - b a s e d c o g n i t i v e t h e r a p y ( M B C T ; T e a s d a l e , S e g a l , &

    W i l l i a m s , 1 9 9 5 ). T h i s 8 - w e e k t r a i n in g w a s a d a p t e d f r o m t h e S t re s s

    R e d u c t i o n a n d R e l a x a t io n P r o g r a m o f t h e U n i v e r s i t y o f M a s s a-

    c h u s e t t s M e d i c a l C e n t e r d e v e l o p e d b y K a b a t - Z i n n ( K a b a t - Z i n n ,

    1 9 9 0 ; K a b a t - Z i n n e t a l. , 1 9 9 2 ) . T h e g o a l o f t h i s p r o c e d u r e i s t o

    i n c r e a s e p a t i e n t s ' a w a r e n e s s o f p r e s e n t, m o m e n t - t o - m o m e n t e x p e -

    r i e n c e . P a t i en t s r e c e i v e e x t e n s i v e p r a c t i c e i n l e a r n i n g t o b r i n g t h e i r

    a t t e n t i o n b a c k t o t h e p r e s e n t , u s i n g a f o c u s o n t h e b r e a t h a s a n

    a n c h o r , w h e n e v e r t h e y n o t i c e t h a t a t t e n t i o n h a s b e e n d i v e r t e d t o

    s t r e a m s o f t h o u g h t s , w o r r i e s , o r g e n e r a l l a c k o f a w a r e n e s s. M B C T

    c o m b i n e s K a b a t - Z i n n ' s m i n d f u l n e s s t e c h n i q u e s w i t h s o m e t e c h -

    n i q u e s d r a w n f r o m c o g n i t i v e t h e r a p y i n a c o m p r e h e n s i v e t r e a t m e n t

    p a c k a g e s p e c i f i c a l ly t a i l o r e d t o t r a i n p a t i e n t s i n s k i l l s r e l e v a n t t o

    t h e p r e v e n t i o n o f d e p r e s s i v e r e l a p s e .

    W e w e r e i n t e r e s te d i n t h e e f f e c t o f th i s t r e a tm e n t o n a u t o b i o -

    g r a p h i c a l m e m o r y b e c a u s e , f i r s t , i t i n c l u d e s a l a r g e n u m b e r o f

    h o m e w o r k t a s k s t h a t t r a in p a t i e n t s t o n o t i c e t h e s p e c i f i c as p e c t s o f

    t h e i r e n v i r o n m e n t , t h u s p o t e n t i a l l y re d u c i n g o v e r g e n e r i c e n c o d i n g .

    ( H i e r a r c h i c a l s ea r c h m o d e l s o f m e m o r y a s s u m e t h a t e n c o d i n g a n d

    r e t r i e v a l s h a r e c o m m o n p r o c e s s e s s o t h a t m a k i n g e n c o d i n g m o r e

    s p e c i f i c w i l l a ls o m a k e r e t r i e v a l m o r e s p e c i f i c. ) S e c o n d , t h e t r a in -

    i n g e x p l i c i t l y f o c u s e s o n a l l o w i n g m e n t a l c o n t e n t s t o o c c u r w i t h o u t

    j u d g i n g t h e m o r t r y i n g t o s u p p r e s s o r a v o i d t h e m , t h u s p o t e n t i a l l y

    r e d u c i n g t h e t e n d e n c y t o t r u n c at e t h e m e m o r y r e t r i e v a l p r o c e s s a s

    a m e a n s o f r e g u l a t i n g a f f e c t .

    T o e x a m i n e t h i s q u e s t i o n , w e a d m i n i s t e r e d t h e s t a n d a r d A u t o -

    b i o g r a p h i c a l M e m o r y T e s t ( B r i t t l e b a n k e t a l . , 1 9 9 3 ) a t o n e o f t h e

    t h r e e s it e s i n v o l v t d ( B a n g o r , W a l e s ) . T h i s t a s k i n v o l v e d g i v i n g

    p o s i t i v e , n e g a t i v e , a n d n e u t r a l c u e w o r d s , o n e a t a t i m e , t o p a t i e n t s

    a n d a s k i n g t h e m t o r e s p o n d w i t h a s p e c i f i c e v e n t f r o m t h e i r p a s t

    t h a t t h e w o r d r e m i n d e d t h e m o f . I t w a s a d m i n i s t e r e d b e f o r e t h e

    s t a rt o f t h e 8 - w e e k s e r i e s o f c la s s e s , a n d a g a i n d u r i n g t h e 1 2 -

    m o n t h s f o l l o w - u p p e r i o d . W e e x a m i n e d t h e s p e c i f i c i t y o f t h e

    r e s p o n s e s t o d e t e r m i n e w h e t h e r o r n o t r e c o v e r e d d e p r e s s e d p a -

    t i e n ts b e c a m e l e s s g e n e r i c f o l l o w i n g t h e t r e a t m e n t .

    M e t h o d

    P a r t i c i p a n t s

    Forty-five patients were recruited from th e clinical services of the

    Comm unity M ental Health Servic e in Bangor, North Wales and by adver-

    tising in the local press for volunteers w ho had been d epressed in the past

    but were n ow recovered. W hatever the sou rce of referral, each participant's

    general practitioner (GP) was contacted for verification and permission to

    assess the patient for the study. To take part in the study, participants

    needed to have had a previous history of at least two episodes of unipolar

    depression meeting DS M-III -R Diagnostic and Stat ist ical Manual for

    Mental Disorders, 3rd ed., revised; American Psychiatric Association,

    1987) criteria for major depressive disorder, and the most recent episode o f

    depression needed to be within the previous 2 years. They needed to be

    currently in remission and to have had a history of treatment with tricyclic

    antidepressant medication but to b e free from antidepressants for at least 12

    weeks before entering the study. All patients remained under outpatient

    care or the care of GPs d uring the study. A structured clinical interview for

    D S M - I I I - R (SCID) w as used to assess past and present d iagnostic status.

    Current clinical remission was confirmed by a SCID indicating that the

    patient had been asymptomatic for at least 8 weeks and had a current

    17-item HRS-D score of 9 or less. Participants were excluded from the

    study if (a) they suffered from the following comorbid psychiatric disor-

    ders: bipolar affective disorder, active drug dependency or abuse, organic

    mental disorders, schizophrenia, schizoaffective disorder, primary

    obs essiv e-co mp ulsiv e disorder, or eating disorders; (b) they could not

    complete measures due to illiteracy; (c) they were receiving additional

  • 7/27/2019 Williams Et Al 2000 OGM in MBCT

    3/6

    52 SHORT RE PORT S

    p s y c h o t ro p i c m e d i c a t i o n o t h e r t h a n b e n z o d i a z e p i n e o r o t h e r n i g h t s e d a t i o n

    ( e . g . l i t h i u m o r n e u r o l e p t ic s ) . A l l p a r t i c i p a n t s g a v e w r i t t e n i n f o r m e d

    c o n s e n t .

    T h e m e a n a g e o f t h e p a r t i c i p a n t s w a s 4 4 . 0 y e a r s (SD = 9 . 5 ) a n d t h e

    m e a n n u m b e r o f y e a r s o f e d u c a t io n w a s 1 4. 5 (SD = 3 . 4 ) . T h e r e w e r e 3 3

    w o m e n a n d 1 2 m e n . T h e m e d i a n n u m b e r o f p r e v i o u s e p i so d e s o f d e p r e s -

    s i o n w a s 4 . 0 .

    a t e r i a l s

    Hamilton Rating Scale for Depression (17-item version, HRS-D; Ham-

    ilton, 1960). T h i s i s a n i n t e r v i e w e r - a d m i n i s t e r e d r a t i n g s c a l e f o r m e a s u r -

    i n g s e v e r i t y o f d e p r e s s i o n , w i d e l y u s e d i n c l i n i c a l t r i a l s , w i t h r e l i a b i l i t y

    c o e f f i c i e n t s o f 0 . 8 4 - 0 . 9 0 . W e a d m i n i s t e r e d it a t e n t r y t o t h e t r i a l a n d a t

    f o l l o w - u p .

    Autobiographical Memory Test (AMT; Williams Broadbem, 1986).

    P a r t i c i p a n t s w e r e r e q u i r e d t o r e c a l l e v e n t s t h a t h a d h a p p e n e d t o t h e m i n

    r e s p o n s e t o c u e s . T h e t i m e p e r i o d f r o m w h i c h e v e n t s c o u l d b e r e c a ll e d w a s

    n o t s p e c i f i e d , a n d p a r t i c i p a n t s w e r e t o l d t h a t t h e e v e n t c o u l d b e i m p o r t a n t

    o r t r iv i a l . I t w a s e m p h a s i z e d t h a t t h e e v e n t s f r o m t h e p a s t s h o u l d b e s p e c i f i c

    e v e n t s ( e v e n t s t h a t l a s t e d l e s s t h a n 1 d a y ) , a n d p r a c t i c e w a s g i v e n u n t i l

    p a r t i c i p a n t s h a d b e e n s u c c e s s f u l i n r e t r ie v i n g a s p e c i f i c m e m o r y . F o r e a c h

    m e m o r y r e s p o n s e , p a rt i ci p a n ts n o t e d h o w l o n g a g o t h e e v e n t h a d o c c u r r e d

    (1 = less than I week, 2 = less than 1 month, 3 = less than 6 months, 4 =

    less than 1 year, and 5 = over 1 year).

    E i g h t e e n w o r d s w e r e u s e d a s c u e s w i t h w h i c h t o p r o m p t p a r t ic i p a n ts f o r

    r e s p o n s e s , 6 n e u t r a l ( e . g . , grass, gigantic), 6 pos i t i ve (e .g . , happy, relieved)

    a n d 6 n e g a t i v e ( e . g . ,

    guilty, hopeless),

    m a t c h e d f o r w o r d f r e q u e n c y . T h e

    p o s i ti v e a n d n e g a t i v e w o r d s w e r e c h o s e n t o b e h i g h o n e m o t i o n a l it y , w i t h

    t h e n e u t r a l w o r d s l o w o n e m o t i o n a l i t y ( J o h n , 1 9 8 8 ) . A n e q u i v a l e n t l i s t

    o f 1 8 w o r d s w a s c o m p i l e d s o t h a t t w o m a t c h e d s e t s ( A a n d B ) w e r e

    a v a i l a b l e . H a l f o f t h e p a r t ic i p a n t s w e r e g i v e n S e t A a t T i m e 1 a n d S e t B a t

    T i m e 2 w i t h t h i s o r d e r b e i n g c o u n t e r b a l a n c e d . ( T h e f u l l l is t o f c u e w o r d s ,

    i n s t r u c t i o n s , a n d p r o c e d u r e a r e a v a i l a b l e f r o m J . M a r k G . W i l l i a m s . )

    Pro ced u r e

    Allocation.

    F o l l o w i n g a b a s e l i n e a s s e s s m e n t , w e r a n d o m l y a l lo c a t e d

    t h e 4 5 p a t i e n t s t o r e c e i v e e i t h e r M B C T ( i n a d d i t i o n t o t r e a t m e n t a s u s u a l

    [ T A U ] ) o r T A U a l o n e . ( T A U p a t i e n t s c o n t i n u e d u n d e r t h e c a r e o f t h e i r

    p h y s i c i a n f o r t h e d u r a t i o n o f t h e t r i a l a n d w e r e i n s t r u c t e d t o u s e w h a t e v e r

    s e r v i ce t h e y w o u l d n o r m a l l y u s e i n t h e e v e n t o f d e p r e s s i v e r e l a p se . ) T h e r e

    w e r e n o d i f f e r e n c e s b e t w e e n t r e a t m e n t a n d c o n t r o l g r o u p s o n a n y p r e tr e a t-

    m e n t v a r ia b l e s : a g e o f t h e p a r t ic i p a n t s ( M B C T , M = 4 2 . 5 y e a r s ;

    SD = 1 1 . 2 ; T A U , M = 4 5 . 7 , SD = 7 . 0 ), n u m b e r o f y e a r s o f e d u c a ti o n

    ( M B C T , M = 1 4 .4 ,

    SD

    = 2 . 7 ; T A U , M = 1 4 . 5 ,

    SD

    = 4 . 1 ), o r n u m b e r o f

    p r e v i o u s e p i s o d e s o f d e p r e s s io n ( M B C T , Mdn = 5 . 0 ; i n t e r q u a r t i l e r a n g e

    [ I Q R ] = 6 . 8 ; T A U , Mdn = 3 . 0 ; I Q R = 5 . 0 ) . T h r e e p a t i e n t s f a il e d to

    c o m p l e t e t h e m e m o r y m e a s u r e a t t h e s e c o n d t e s ti n g . A n o t h e r p a ti e n t w a s

    i n a d v e r te n t l y g i v e n t h e s a m e l i st o f m e m o r y c u e s o n b o t h o c c a s i o n s , s o

    t h e i r d a t a w e r e n o t i n c l u d e d . D a t a f o r t h e s e p a t i e n t s s h o w e d t h a t t h e y d i d

    n o t d i f f e r f r o m t h e o t h e r p a t i e n t s i n a n y r e s p e c t , n e i t h e r i n t h e i r l e v e l o f

    d e p r e s s i o n n o r t h e i r i n i t i a l a u t o b i o g r a p h i c a l m e m o r y p e r f o r m a n c e . T h e

    n u m b e r s o f p a r t i c i p a n t s i n t h e p r e s e n t s t u d y w a s t h e r e f o r e 4 1 ( M B C T ,

    n = 2 1 , 1 6 w o m e n , M a g e = 4 2 . 1 , SD = 1 1 .7 ; T A U , n = 2 0 , 1 4 w o m e n ,

    M a g e = 4 5 . 6 , SD = 7 .2 ) .

    A u t o b i o g r a p h ic a l m e m o r y w a s t e s te d o n t w o o c c a s i o n s , o n c e b e f o r e

    a l l o c a t i o n t o M B C T o r T A U ( T i m e 1 ) , a n d a g a i n d u r i n g t h e 1 2 - m o n t h s

    f o l l o w - u p p e r i o d ( T i m e 2 ). T h e m e a n t e s t - r e t e s t i n t e r v a l w a s a p p r o x i -

    m a t e l y 6 m o n t h s ( 4 m o n t h s f o ll o w i n g t h e e n d o f t r e a t m e n t) a n d d i d n o t

    d i f f e r b e t w e e n t h e g r ou p s ( M B C T , M = 1 92 d a y s , SD = 4 4 ; T A U , M =

    1 9 5 d a y s , SD = 67 ; t [39 ] = .13 , ns). D e p r e s s i o n l e v e l ( m e a s u r e d b y

    H R S - D ) w a s a s s e s s e d o n th e s a m e o c c a s i o n s a s t he m e m o r y t e s ti n g .

    R e s u l t s

    o o d

    B e c a u s e t h e t r e a t m e n t w a s d e s i g n e d t o p r e v e n t f u t u r e d e p r e s s i v e

    r e l a p s e i n p e o p l e w h o w e r e c u r r e n t l y i n r e m i s s i o n , n o s p e c i fi c

    r e d u c t i o n i n m o o d s y m p t o m s w a s p r e d i c te d f o r t h e t r e a t m e n t ,

    N e v e r t h e l e s s , w e c o u l d n o t r u le o u t t h e p o s s i b il i ty t h a t s o m e

    c h a n g e i n d e p r e s s i o n d u e t o th e t r e a t m e n t m a y h a v e h a d a n e f f e c t

    o n m e m o r y p e r f o r m a n c e , s o w e a n a l y z e d H R S - D s c o r e s f i rs t. A 2

    ( T i m e : 1 , 2 ) x 2 ( G r o u p : M B C T , T A U ) m i x e d a n a l y s i s o f v a r i a n c e

    ( A N O V A ) w a s c a r r i e d o u t . M e a n s a n d s t a n d a r d d e v i a ti o n s a r e

    s h o w n i n T a b l e 1 . W e f o u n d n o s i g n i f ic a n t m a i n e f f e c t s f o r t i m e ,

    F ( 1 , 3 9 ) = 1 . 8 2 , MSE = 1 3 . 5 3 , p = . 1 9 ] ; g r o u p , F ( 1 , 3 9 ) = 2 . 5 8 ,

    MSE = 1 9 . 4 3 , p = . 1 2 , o r f o r t h e G r o u p T i m e in t e r a c t i o n , F ( 1 ,

    3 9 ) = 1 . 2 4 ,

    MSE

    = 1 3 . 5 3 , p - = . 2 7 .

    Autobiographica l Memory Responses

    P a r t i c i p a n ts f i rs t r e s p o n s e s t o e a c h o f th e 1 8 c u e w o r d s p r e -

    s e n t e d o n e a c h o c c a s i o n w e r e a n a l y z e d . I f p a t ie n t s d i d n o t r e s p o n d

    w i t h i n 3 0 s f o r a n y c u e , t h is w a s s c o r e d a s a n o m i s s i o n ( s e e T a b l e

    1 ). M e m o r y r e s p o n s e s w e r e t h e n c a t e g o r i z e d i n t o t h r e e t y pe s :

    specific ( a m e m o r y f o r a p a r t i c u l a r e v e n t l a s t i n g 1 d a y o r l e s s , e . g ,,

    g o i n g t o a c o n c e r t la s t s u m m e r ) , categoric ( a m e m o r y r e s p o n s e

    t h a t s u m m a r i z e d a n u m b e r o r c a t e g o r y o f e v e n t s , e .g . , g o i n g to

    T a b l e 1

    Means a nd Standard Deviations fo r the Hamilton Depression Scale and Memory Variables

    for MBCT and TAU Groups at Times 1 and 2

    M B C T T A U

    T i m e 1 T i m e 2 T i m e 1 T i m e 2

    V a r i a b l e

    M SD M SD M SD M SD

    M o o d

    H a m i l t o n 4 . 2 2 . 6 4 . 4 4 . 5 4 . 9 2 . 7 6 . 9 5 . 6

    M e m o r y

    No . o f om is s io ns 1 .9 1 .4 2 .3 1 .9 1 .6 1 .9 1 .8 1 .8

    M e a n l a t e n c y ( s ) 9 . 4 2 . 9 9 . 6 2 . 2 1 0 .1 3 . 0 1 1 .3 3 . 4

    M e m o r y a g e 4 . 1 2 . 4 3 . 0 2 . 4 3 . 9 2 . 4 2 . 7 2 . 3

    Note. M B C T = m i n d f u l n e s s - b a s e d c o g n i t i v e t h e r a p y ; T A U = t r e a t m e n t a s u su a l .

  • 7/27/2019 Williams Et Al 2000 OGM in MBCT

    4/6

    SH O R T R EPO R TS 1 5 3

    c o n c e r t s a s a c h i l d ) , a n d e x t e n d e d ( a m e m o r y o f a p a r t i c u l a r t i m e

    p e r i o d l a s t i n g l o n g e r t h a n a d a y , e . g . , m y 3 - w e e k h o l i d a y i n

    F r a n c e ) . T h i s c a t e g o r i z a t io n w a s d o n e b y a n i n d e p e n d e n t r a t e r w h o

    w a s u n a w a r e o f t r e a t m e n t a l l o c a t i o n a n d t i m e o f t e s t i n g o f t h e

    m a t e r i a l b e i n g r a t e d . A r e l i a b i l i t y c h e c k o n d e g r e e o f s p e c i f i c i t y o f

    r e s p o n s e s w a s c a r d e d o u t . F o l l o w i n g t h e m e t h o d o f B a d d e l e y a n d

    W i l s o n ( 1 9 8 6 ) , w e s c o r e d m e m o r y r e s p o n s e s o n a s c a l e f r o m 3

    t o 1 , h i g h e r s c o r e s r e f l e c t i n g g r e a t e r s p e c i f i c i ty . A s e c o n d i n d e -

    p e n d e n t r a t e r w h o w a s a l s o u n a w a r e o f t r e a t m e n t c o n d i t io n a n d

    t i m e o f t e s t i n g c a t e g o r i z e d a 1 2 s a m p l e o f t h e f i r s t r a t e r ' s

    r e s p o n s e s ( N = 8 8 ). T h e P e a r s o n c o r r e l a t io n c o e f f ic i e n t b e t w e e n

    t h e t w o s e t s o f r a t i n g s w a s 0 . 8 6 d f = 8 6 , p < .0 0 1 ) .

    W e a n a l y z e d d a t a f o r t h e p r o p o r ti o n o f r e s p o n s e s t h a t w e r e o f

    e a c h m e m o r y t y p e w i t h a se p a r a t e 2 (G r o u p : M B C T , T A U ) 2

    ( T i m e : p r e , p o s t ) x 3 ( V a l e n c e : p o s i t i v e , n e g a t i v e , n e u t r a l ) m i x e d

    a na l~ cs is o f c o v a r i a n c e ( A N C O V A ) , c o v a r y i n g o u t H R S - D s c o r e s

    a t T i m e 2 . M e a n s a n d s t a n d a r d d e v i a ti o n s a r e s h o w n i n T a b l e 2 .

    N o n e o f t h e t y p e s o f m e m o r y y i e l d e d a s i g n i f i c an t v a l e n c e e ff e c t,

    s o t h e d a t a a r e s h o w n c o l l a p s e d a c r o s s t h e p o s i t i v e , n e g a t i v e , a n d

    n e u t r a l c u e s . T h e e x t e n d e d m e m o r y c a t e g o r y o f r e s p o n s e a p p e a r e d

    r e l a t i v e l y r a r e l y ( o c c u r r i n g , o n a v e r a g e , i n r e s p o n s e t o o n l y 1 c u e

    p e r p e r s o n ) s o w e r e n o t a n a l y z e d f u r t h e r . W e a n a l y z e d r e t r i e v a l

    l a t e n c ie s t o c h e c k t h a t a n y d i f f e r e n c e s i n c a t e g o r ic m e m o r i e s w e r e

    n o t m e r e l y d u e t o o v e r a l l i m p a i r e d p e r f o r m a n c e o n t h e t a s k ( s e e

    T a b l e 1 ). W i t h r e g a r d to o m i s s io n s , a 2 2 A N C O V A s h o w e d n o

    s i g n i f i c a n t m a i n e f f e c t s o r i n t e r a c t i o n s .

    P r o p o r t i o n o f s p e c i fi c m e m o r i e s . T h e r e w a s a m a i n e f f e c t o f

    t i m e , F ( 1 , 3 9 ) = 1 5 . 7 2 , M S E = 0 . 1 5 , p = . 0 0 0 5 , d u e t o a g e n e r a l

    t e n d e n c y f o r b o t h g r o u p s t o r e c a l l a g r e a t e r p r o p o r t i o n o f s p e c i f i c

    m e m o r i e s a t T i m e 2 ( 8 0 ) t h a n a t T i m e 1 ( 7 1 ) . T h e r e w a s n o

    s i g n i f i c a n t e f f e c t o f g r o u p , F ( 1 , 3 8 ) = 2 . 5 6 , b u t t h e r e w a s a

    s i g n i f ic a n t G r o u p T i m e i n t e r a c t io n , F ( 1 , 3 9 ) = 4 . 9 8 , M S E = 0 .0 5 ,

    p = . 0 31 . P l a n n e d c o m p a r i s o n s s h o w e d t h i s i n te r a c t i o n t o b e d u e

    t o t h e f a c t t h a t a t T i m e 1 t h e r e w a s n o s i g n i f i c a n t d i f f e r e n c e

    b e t w e e n t h e g r o u p s i n t h e p r o p o r t i o n o f s p e c i fi c m e m o r i e s ( 7 2 i n

    t h e M B C T , a n d 7 0 i n t h e T A U g r o u p ). A t T i m e 2 , h o w e v e r , t h e

    M B C T g a v e s p e c if i c m e m o r i e s 8 5 o f t h e t i m e v e r s u s o n l y 7 4

    f o r t h e T A U g r o u p , t ( 3 9 ) = 2 . 3 4 , p = 0 . 0 3 .

    P r o p o r t i o n o f c a t e g o r i c m e m o r i e s T h e r e w a s a m a i n e f f e c t o f

    t i m e , F ( 1 , 3 9 ) = 1 4 . 3 6 , M S E = 0 . 1 2 , p = . 0 0 1 , d u e t o a t e n d e n c y

    f o r b o t h g r o u p s t o r e c a l l l e s s c a t e g o r ic m e m o r i e s a t T i m e 2 ( 1 5 )

    t h a n a t T i m e 1 ( 2 3 ) . H o w e v e r , t h i s e f f e c t w a s q u a l i f i e d b y a

    s i g n i f i c a n t G r o u p T i m e in t e r a c t i o n , F ( 1 , 3 9 ) = 8 . 4 2 ,

    M S E = 0 . 0 7 , p = . 0 0 6 . P l a n n e d c o m p a r i s o n s s h o w e d t h i s i n t e r -

    a c t i o n to b e d u e t o t h e f a c t t h a t i n t h e M B C T g r o u p t h e p r o p o r t i o n

    o f c a t e g o r i c m e m o r i e s r e c a l le d f e l l f r o m 2 4 o f r e s p o n s e s a t

    T i m e 1 t o 1 0 o f r e s p o n s e s a t T i m e 2 , e n d i n g s i g ni f i c a n tl y l o w e r

    t h a n t h e p r o p o r t io n r e c a l l e d b y t h e T A U ( c o n t r ol ) g r o u p a t T i m e 2

    (1 9 ) , t (3 9 ) = 2 .2 8 , p = .0 3 .

    L a t e n c y t o R e s p o n d

    T o c h e c k t h a t t h e p a t t e rn o f r e s u l t s w a s n o t d u e t o g e n e r a l

    s l u g g i s h n e s s i n r e s p o n d i n g t o t he c u e w o r d s , w e a n a l y z e d t h e m e a n

    r e s p o n s e l a t e n c i e s ( s h o w n i n T a b l e 1 ) . R e s u l t s o f a 2 ( G r o u p :

    M B C T , T A U ) 2 (T i m e : 1, 2 ) m i x e d A N O V A s h o w e d n o

    s i g n i f i c a n t m a i n e f f e c t o f g r o u p , F ( 1 , 3 9 ) = 2 . 1 9 , M S E = 1 3 .1 4 ,

    p = . 1 5 , o r o f t i m e , F ( 1 , 3 9 ) = 2 . 8 7 , M S E = 3 . 3 3 , p = . 1 0 , n e i t h e r

    w a s t h e r e a s i g n i f i c a n t G r o u p T i m e i n t e r a c t i o n , F ( 1 , 3 9 ) = 1 . 1 7,

    M S E = 3 .33 , p = .29 .

    M e m o r y A g e

    T h e r e d u c t i o n i n n u m b e r o f c a t e g o r ic m e m o r i e s f o l l o w i n g t r e at -

    m e n t , d e s c r i b e d e a r li e r , m a y b e d u e t o t h e M B C T g r o u p r e t r i e v i n g

    e v e n t s f r o m a m o r e r e c e n t t im e f r a m e t h a n t h e c o n t r o l p at i e nt s . F o r

    e a c h m e m o r y r e s p o n s e , p a t i e n t s h a d n o t e d h o w l o n g a g o t h e e v e n t

    h a d o c c u r r e d ( 1 =

    l e s s than 1 we e k , 2 = le s s than 1 month , 3 =

    le s s than 6 months , 4 = le s s than I y e ar , and 5 = ov e r I y e ar ) . F o r

    e a c h p a t i e n t ' s s e t o f r e s p o n s es , t h e m o d a l t i m e s i n c e t h e r e t ri e v e d

    e v e n t s h a d o c c u r r e d w a s r e c o r d e d ( u s i n g t h e m o d e b e c a u s e o f t h e

    a b n o r m a l d i s t r i b u ti o n s o f e a c h i n d i v i d u a l ' s e v e n t a g e s) . M e a n

    m e m o r y a g e s f o r e a c h g r o u p a r e s h o w n i n T a b l e 1 . A 2 ( G r o u p :

    M B C T , T A U ) 2 ( T i m e : 1, 2 ) m i x e d A N O V A w a s ca r r ie d o u t.

    W e f o u n d a s i g n i f i c a n t m a i n e f f e c t f o r t i m e : m o r e d i s t a n t e v e n t s

    w e r e r e c a l l e d a t T i m e 1 ( M = 4 . 0 5 ,

    S D

    = 2 . 3 8) c o m p a r e d w i t h

    T i m e 2 ( M = 2 . 8 3 , S D = 2 .3 4 ) , F (1 , 3 9 ) = 9 .0 7 , M S E = 3 . 3 7 , p =

    . 0 0 5 . T h e r e w a s n o s i g n i f i c a n t m a i n e f f e c t f o r g r o u p , F ( 1 , 3 9 ) =

    19, M S E = 8 . 0 2 , p = . 6 7 , n e i t h e r w a s t h e r e a s i g n i f i c a n t G r o u p

    T i m e i n t e r a c t i o n , F ( 1 , 3 9 ) = . 0 4 , M S E = 3 .3 7 , p = .8 5 . In su m,

    b o t h g r o u p s r e t r i e v e d m e m o r i e s f r o m m o r e r e c e n t t i m e p e r i o d s o n

    t h e s e c o n d o c c a s i o n o f t e s t in g , b u t t h e r e w a s n o e v i d e n c e t h a t t h e

    M B C T g r o u p d i d s o m o r e t h a n t h e c o n t r o l ( T A U ) g r o u p .

    D i s c u s s i o n

    T h e a i m o f t h e p r e s e n t s t u d y w a s t o e x a m i n e t h e s t a b il i ty o f t h e

    t e n d e n c y t o b e o v e r g e n e r a l i n r e t r ie v a l o f a u t o b i o g r a p h i c a l m e m -

    T a b l e

    M e a n s a n d S t a n d a r d D e v i a t i o n s f o r t h e P r o p o r t i o n o f S p e ci f ic , C a t e g o ri c , a n d E x t e n d e d

    M e m o r i e s R e c o r d e d a t T i m e s 1 a n d 2 f o r M B C T a n d T A U G r o u p s

    M B C T T A U

    Ti me 1 T i me 2 T i me 1 T i me 2

    M e mo r i e s M S D M S D M S D M S D

    Specific 0.72 0.14 0.85 0.13 0.70 0.16 0.74 0.17

    Categoric 0.24 0.13 0.10 0.08 0.21 0.11 0.19 0.16

    Extended 0 .04 0 .06 0 .05 0 .08 0 .09 0 .06 0.07 0 .06

    Note. MB CT = mindfu lne ss-based cogni t ive therapy; TAU = t rea tment as usual.

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    1 5 4 S H O R T R E P OR T S

    t r y i n f o r m e r l y d e p r e s s e d p a ti e n t s. T h e b a l a n c e o f e v i d e n c e f r o m

    p r e v i o u s s t u d i e s h a d s u g g e s t e d t h a t c a t e g o r i c m e m o r y w a s a l o n g -

    t e r m c o g n i t i v e s ty l e p e r s is t i n g d e s p i t e s h o r t - t e r m c h a n g e s i n m o o d .

    T h e f i n d i n g s o f t h i s st u d y s h o w t h a t w h e n r e c o v e r e d d e p r e s s e d

    p a t i e n t s u n d e r g o t r a i n i n g t h a t i n c l u d e s i n s t r u c t i o n s t o f o c u s m o r e

    c a r e f u l l y o n e v e r y d a y e v e n t s a n d t o a l l o w c o g n i t i o n s t o o c c u r

    w i t h o u t t r y i n g t o a v o i d o r s u p p r e ss t h e m , t h e t e n d e n c y t o r e t r i e v e

    e v e n t s i n a c a t e g o r i c s t y l e i s re d u c e d . F u r t h e r m o r e , c o n s i s t e n t w i t h

    e a r l i e r st u d i e s s h o w i n g t h a t t h i s a s p e c t o f m e m o r y i s n o t m o o d -

    s t a t e d e p e n d e n t , o v e r g e n e r a l i t y i n m e m o r y w a s r e d u c e d s i g n i f i -

    c a n tl y i n t h e M B C T g r o u p d e s p it e t h e re b e i n g n o c h a n g e i n m o o d

    s c o r e s o v e r t h i s i n t e r v a l : T h e m e m o r y c h a n g e s w e r e n o t m o o d

    dr ive n .

    A l t h o u g h m o o d c h a n g e c o u l d n o t e x p l a i n t h i s e f f e c t , i t r e m a i n s

    p o s s i b l e t h a t c h a n g e i n s o m e o t h e r , t h i r d v a r i a b l e w a s b e i n g

    a f f e c t e d b y t h e M B C T t r e a t m e n t a n d t h e n a f f e c t i n g m e m o r y . F o r

    e x a m p l e , i t i s p o s s i b le t h a t t r e a t m e n t s i m p l y a f f e c t s t h e a m o u n t o f

    e n e r g y t h a t p a t i e n t s a r e p r e p a r e d t o p u t i n t o p s y c h o l o g i c a l t a s k s

    suc h a s the se . A re la te d a r t i f a c tua l e xpla na t ion for the r e su l t s c ould

    b e t h a t , f o l l o w i n g 8 w e e k s o f c o n t a c t w i t h a c l a s s - b a s e d i n s t r u c -

    t i o n , p at i e n ts m a y h a v e b e e n m o r e u s e d t o r e c e i v i n g a n d a c t i n g o n

    i n s t ru c t i o n s , a f f e c t i n g t h e i r a b i l i t y t o p e r f o r m t h e t a s k . I f t h a t w e r e

    t h e c a s e , o n e m i g h t e x p e c t a n o v e r a l l b e t t e r p e r f o r m a n c e o n t h e

    m e m o r y t a s k : T h e l a t e n c y t o r e s p o n d m i g h t b e f a s t e r f o r t h e

    M B C T t r e a t m e n t g r o u p a t T i m e 2 o r t h e r e m i g h t b e f e w e r o m i s -

    s i o n s a t T i m e 2 . T h e r e w e r e n o s u c h e f f e c t s , h o w e v e r . I n f a c t , i f

    a n y t h i n g , t h e t r e n d w a s i n t h e o p p o s i t e d i r e c t i o n , w i t h s l i g h t l y

    m o r e o m i s si o n s f o l l o w i n g M B C T t re a tm e n t , w h i c h , o n c e e x -

    c l u d e d , m i g h t e x a g g e r a t e t h e a p p a re n t i m p a c t o f t h e t r e a t m e n t o n

    t h e p r o p o r t i o n o f s p e c i f i c m e m o r i e s . O m i s s i o n s w e r e e x c l u d e d

    b e f o r e a n a l y s is o f m e m o r y r e s p o n s e s b e c a u s e t h e y a r e a m b i g u o u s :

    T h e y m a y m e a n t h at n o m e m o r y h a s b e e n r e tr i e v ed , o r a m e m o r y

    h a s b e e n r e t r i e v e d t h a t t h e p e r s o n d o e s n o t w i s h t o r e p o r t , o r t h a t

    t h e t r e a t m e n t h a s a l e r t e d t h e p a r t i ci p a n t t o t h e i n a p p r o p r i a t e n e s s o f

    a c a t e g o r i c m e m o r y w h e n a s p e c i f i c m e m o r y i s u n a v a i l a b l e . T h e

    l a t t e r p o s s i b i l i t y i s c o n s i s te n t w i t h p a r t i c i p a n t s b e i n g m o r e a w a r e

    o f t h e i r r e t r i e v a l p r o c e s s e s , c o n s i s t e n t w i t h t h e a i m s o f t h e

    t r e a tm e nt .

    T h e f i n a l p o s s i b l e a r t i f a c t u a l e x p l a n a t i o n i s t h a t t h e t r e a t m e n t

    g r o u p m i g h t h a v e s a m p l e d e v e n t s f r o m a m o r e r e c e n t t i m e f ra m e

    f o l l o w i n g t r e a t m e n t . A n e x c e s s n u m b e r o f e v e n t s f r o m t h e p e r i o d

    s i n c e t h e t r e a t m e n t s t a r te d m i g h t c h a n g e t h e p r o f i l e o f t h e r e t r i e v a l

    p r o t o c o l s i n t h e M B C T g r o u p t o f a v o r , b y a c c i d e n t , m o r e r e c e n t

    e v e n t s a n d t h e r e f o r e l e s s c a t e g o r i c m e m o r i e s . H o w e v e r , b o t h

    g r o u p s s h o w e d a t e n d e n c y t o r e t r i e v e fr o m a m o r e r e c e n t p e r i o d o n

    s e c o n d t i m e o f t e s t i n g , a n d t h e r e w a s n o d i f f e r e n c e b e t w e e n t h e

    g r o u p s i n t h e t i m e e l a p s e d s i n c e t h e r e t r i e v e d e v e n t s t o o k p l a c e .

    O f c o u r s e , t h e p r e s e n t d a t a c a n o n l y b e s e e n a s p r e l i m i n a r y f o r

    t w o r e a s o n s . F i r s t , t h e r e w a s n o p l a c e b o c o n t r o l g r o u p , s o w e

    c a n n o t d e f i n i t i v e l y a t t ri b u t e t h e c h a n g e s i n m e m o r y t o a s p e c i f i c

    e f f e c t o f t h e M B C T . S e c o n d , t h e r e w a s n o i n d e p e n d e n t m e a s u r e

    t a k e n d u r i n g t h e t r e a t m e n t t o c h e c k t h a t i n d i v i d u a l s w e r e i n f a c t

    c h a n g i n g t h e i r c o g n i t i v e s t y l e i n t h e w a y p r e d i c t e d b y t h e t h e o r y .

    N e v e r t h e l e s s , t h e m a i n i n t e n t io n o f t h is s t u d y w a s t o s e e w h e t h e r

    o v e r g e n e r a l m e m o r y c o u l d b e m o d i f i e d . H o w s u c h c h a n g e o c c u r s

    w i l l b e f o r f u t u r e r e s e a r c h t o d e t e r m i n e . T h e f i n d i n g t h a t i t c a n

    c h a n g e h a s p o t e n t i a l l y i m p o r t a n t c l i n i c a l i m p l i c a t i o n s .

    W i l l i a m s ( 1 9 9 6 ) r e v i e w e d e v i d e n c e s u g g e s t i n g t h a t s u c h a s t y l e

    a r i s es e a r l y i n d e v e l o p m e n t . H y p e r s e n s i t i v i t y t o a f f e c t i v e l y t o n e d

    a s p e c t s o f e v e n t s ( p o s i t i v e a n d n e g a t i v e ) , w h e t h e r p r e s e n t a s a n

    a s p e c t o f t e m p e r a m e n t a l s t y l e o r d u e t o n e g a t i v e e x p e r i e n c e s , g i v e s

    r i s e t o a t e n d e n c y t o e n c o d e s p e c i f i c a s p e c t s o f t h e e n v i r o n m e n t i n

    t e r m s o f t h e i r m o r e g e n e r a l s c h e m a t i c a s p e c t s . T h i s l e a d s t o a

    h a b i t u a l u s e o f e n c o d i n g a n d r e t r i e v a l s t r a t e g i e s i n w h i c h m o r e

    g e n e r a l a s p e c t s o f e v e n t s ( i n t e r m e d i a t e g e n e r a l d e s c r i p t io n s ) a r e

    r e p r e s e n t e d i n m e m o r y , w i t h p o o r e r s t r a t e g i c a c c e s s t o s p e c i f i c

    e p i s o d i c e x e m p l a r s . T h i s s t y l e a f f e c t s t h e p r o c e s s i n g o f f u r t h e r

    e v e n t s ( p o s i t i v e , n e g a t i v e , o r n e u t r a l ) b u t h a s p a r t i c u l a r i m p l i c a -

    t i o n s f o r th e s a t i s fa c t o r y e m o t i o n a l p r o c e s s i n g o f a n y n e w n e g a t i v e

    e ve nt tha t oc c ur s . F i r s t , suc h a r e t r i e va l s ty le m a ke s the s t r a te g ic

    r e c o l l e c t i o n o f s p e c i f i c a s p e c t s o f s u c h e v e n t s ( n e c e s s a r y f o r

    re c oding , r e a t t r ibu t ion , e tc . ) e f for t fu l a nd unl ike ly to be s a t i s f a c -

    t o r i l y a c c o m p l i s h e d . S e c o n d , s p e c i f i c a s p e c ts o f e v e n t s w i l l c o m e

    t o b e a s s o c i a t e d w i t h m o r e i n t e n s e a f f e c t a n d l e a d i n c r e a s i n g l y t o

    a t t e m p t s t o a v o i d s p e c i f i c r e t ri e v a l .

    M i n d f u l n e s s - b a s e d c o g n i t i v e th e r a p y a d d r e s s e s t h i s a v o i d a n t

    m o d e o f p r o c e s s i n g b y e n c o u r a g i n g p a t i e n t s t o p r a c t i c e n o t i ci n g

    e l e m e n t s o f t h e i r e x p e r i e n c e a n d t o d o s o i n a n o n j u d g m e n t a l w a y .

    I n t h i s w a y , i t e n c o u r a g e s n o t o n l y m o r e s p e c i f i c e n c o d i n g o f

    e v e n t s b u t a l s o m o r e s p e c i f i c r e tr i e v a l o f p a s t e v e n t s b y r e d u c i n g

    t h e t e n d e n c y f o r i n d i v i d u a l s t o a b o r t t h e s e a r c h p r o c e s s . F u r t h e r

    r e s e a r c h w i l l b e n e e d e d t o e s t a b l i s h h o w m u c h o f t h e c h a n g e i n

    m e m o r y c o m e s a b o u t a s a r e su l t o f th e M B C T ' s e f f e c t o n e n c o d i n g

    v e r s u s r e t r i e v a l . N e v e r t h e l e s s , t h e f i n d i n g t h a t o v e r g e n e r a l m e m -

    o r y s t y l e c a n b e c h a n g e d i s p o t e n t i a l l y i m p o r t a n t c l i n i c a l l y . F o r

    e x a m p l e , t h e r e a r e n o w a n u m b e r o f s t u d i e s s h o w i n g t h a t p a t i e n t s

    w h o h a v e d i f f i c u l t y i n b e i n g s p e c i f i c i n t h e i r m e m o r y h a v e p r o b -

    l e m s i n f i n d i n g s u f f i c i e n t n u m b e r s o f s o l u t i o n s a n d s u f f i c i e n t l y

    e f f e c t i v e s o l u t io n s t o c u r r e n t i n t e r p e r so n a l p r o b l e m s ( E v a n s e t a l . ,

    1992; God da rd e t a l. , 1996; S id le y e t a l . , 1997). B e c a u se soc ia l

    p r o b l e m - s o l v i n g d e f i c i t s a r e k n o w n t o b e a p r e v a l e n t f e a t u r e o f

    d e p r e s s i o n ( N e z u & N e z u , 1 9 8 9 ) , i t is i m p o r t a n t t o k n o w t h a t o n e

    o f t h e u n d e r l y i n g p r o c e s s e s t h a t c o n t r i b u t e s t o p o o r p r o b l e m

    s o l v i n g - - o v e r g e n e r a l i t y i n a u t o b io g r a p h i ca l m e m o r y - - c a n b e

    c h a n g e d b y t r e a t m e n t a n d t h a t s y s t e m a t i c i n s t ru c t i o n i n a t t e n t io n a l

    c o n t r o l i s p r o m i s i n g a s a p r e l i m i n a r y m e t h o d b y w h i c h t o b r i n g

    a b o u t s u c h c h a n g e .

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    A c c e p t e d M a y 5 , 1 9 9 9