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Where to Find the Course: Home Page: Wiki: .
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Where to Find the Course:
Home Page: http://gspp.berkeley.edu/iths/RDStrategies/Home.htm
Wiki: https://bspace.berkeley.edu/portal
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Course Overview:Course Overview:Thinking Through the ProblemThinking Through the Problem
Stephen M. Maurer
Designing Strategies for Neglected Disease ResearchLaw 284.26
Public Policy 190/290
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Where to Find the Course:
Home Page: http://gspp.berkeley.edu/iths/RDStrategies/Home.htm
Wiki: https://bspace.berkeley.edu/portal
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Owner’s Manual
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Owner’s Manual
“The power of instruction is seldom of much efficacy except in those happy dispositions where it is almost superfluous."
- Edward Gibbon
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This is nominally …
A Course About a Specific Innovation Problem (Mostly Economics)
But you should think of it as …
A Course About R&D Incentives
Ongoing Research
A Course About Giving Practical Advice
(A Potential Initiative)
The Hard (Also Rewarding, Interesting) Part…
Goals
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Interdisciplinary Problems
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Three views- Cartoon intuition- “How to do public policy”- A worked example.
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InterdisciplinaryProblems
Drugs for U.S.
Drugs for DevelopingWorld
The Problem
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Political Science –Redistribution
Drugs for U.S.
Drugs for DevelopingWorld
InterdisciplinaryProblems
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Biology & Engineering
Drugs for U.S.
Drugs for DevelopingWorld
InterdisciplinaryProblems
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This Course (Primarily)
Drugs for U.S.
Drugs for DevelopingWorld
InterdisciplinaryProblems
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Incentives Design
Drugs for U.S.
Drugs for DevelopingWorld
InterdisciplinaryProblems
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Doing Public Policy- Define Goals Understand
Identify Bottlenecks Design a (Hopefully) Elegant Response.
InterdisciplinaryProblems 2
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Doing Public Policy- Define Goals Understand
Identify Bottlenecks Design a (Hopefully) Elegant Response.
1. Define GoalsChoose an Objective Function!
InterdisciplinaryProblems 2
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Doing Public Policy- Define Goals Understand
Identify Bottlenecks Design a (Hopefully) Elegant Response.
2. UnderstandTake Theory Seriously
- “Pharma doesn’t want to prevent diseases, selling drugs is more lucrative.”
- “Prizes are only paid if you get a drug.”
*Making Contact Between Theory and Evidence
InterdisciplinaryProblems 2
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Doing Public Policy- Define Goals Understand
Identify Bottlenecks Design a (Hopefully) Elegant Response.
3. Identify Bottlenecks- What are the Main Innovation Challenges?
- The Innovation Toolbox
InterdisciplinaryProblems 2
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Doing Public Policy- Define Goals Understand
Identify Bottlenecks Design a (Hopefully) Elegant Response.
4. Design a Response
- “No dominant incentive mechanism”
- What are the Main Innovation Challenges?
- The Innovation Toolbox
InterdisciplinaryProblems 2
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A Concrete Example:Prizes vs. PPPs
PrizesHow Big Should the Prize Be?$800m ± $115m
PPPsPicking WinnersManaging Outsourced R&DGetting the Best Ideas
… And Also Patents? Access Pricing
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Innovation Economics
Efficient Procurement(Getting a Good Price) Usually: Efficiency: How intense do we want
R&D effort to be?Here: Limited Budget: How much will it
cost?
Information Asymmetry/Agency Problems(Managing Outsourced R&D)Managers Don’t Know EverythingResearchers May Have Diverging Goals
Recurring Themes
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Innovation Economics, ctd…
Eliciting Information(Getting Good Ideas)Good Ideas are (Often) Widely DistributedCounterexamples
A prizes for reduced DALYs?A prize for optimized drug
compounds?
Efficient AccessPatentsPrices matter!
Recurring Themes
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“It’s a Great Idea, But Government Will Never Listen”
A Lawyer’s Faith
Comment
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Lecture Topic Speaker
Week 1 Introduction AK, SMJan. 13-15
Defining The Goals:
Week 2 Disease Burdens Kirk Smith, Julia Jan. 20-22 R&D Priorities Walsh
Week 3A The Drug Discovery David RidleyJan. 27 Business
Week 3B, Drug Development Jim McKerrow4A Science; The Neglected Solomon NwakaJan. 29- Disease Pipeline
Roadmap
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Lecture Topic Speaker
Week Innovation Economics SM, AK4B – 5BFeb. 5-12
Leading Proposals:
Week 6A Price Discrimination and Keith MaskusFeb. 17 Patent Pools
Week 6B Financing Proposals Saul WalkerFeb. 19
Week 7A Prizes Aidan Hollis
Roadmap
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Lecture Topic Speaker
Week 7B Funding Clinical Trials Dean BakerFeb. 26
Week 8A Advanced Market Michael KremerMar. 3 Commitments
Mar. 6 Critical Evaluations Due
Week 9A Private Public Suerie MoonMar. 10 Partnerships
Week 9B Regulatory Approval David Kessler
Roadmap
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Lecture Topic Speaker
Week 10B Political Economy Richard WilderMar. 17-19 James Love
Week 11-12 Incentive Design Choices SM, Brian Wright,Mar. 31- Economists Roundtable Suzanne ScotchmerApr. 9
Week 13 Delivering Healthcare Julia WalshApr. 14-16 Ndola Prata
Week 14 Student Papers; --Apr. 20-21 Concluding Remarks
Roadmap
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Class Participation (25%)Wiki(In Class Discussion)Lecture Reporter
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Midterm ProjectCritique an Existing Initiative (25%)Self-assemble
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Final ProjectWhite Paper (50%)Groups of 4-6 studentsIdeal: Self-assemble!
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Logistics
Home Page: http://gspp.berkeley.edu/iths/RDStrategies/Home.htm
Wiki: https://bspace.berkeley.edu/portal