Wehrens et al. 2001. Circulation. 102:584-90
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Wehrens et al. 2001. Circulation. 102:584-90 Abriel et al. 2001. Circ. Res. 88:740-5 Rivolta et al. 2001. JBC. 276(33):30623-30630 WT Simulation Veldkamp et al. 2000. Circ. Res. 86:e91-97 Supplemental Figure 1 P2/P1 P1-P2 interval (ms) A B C D E 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 1 10 100 1000 Kambouris et al. 2000. JCI. 105:1133-40 F WT WT WT WT WT Recovery time (ms)
description
A. WT Simulation. P2/P1. P1-P2 interval (ms). B. WT. Veldkamp et al. 2000. Circ. Res. 86:e91-97. C. Kambouris et al. 2000. JCI. 105:1133-40. WT. D. Rivolta et al. 2001. JBC. 276(33):30623-30630. WT. Recovery time (ms). E. Wehrens et al. 2001. Circulation. 102:584-90. WT. F. - PowerPoint PPT Presentation
Transcript of Wehrens et al. 2001. Circulation. 102:584-90
Wehrens et al. 2001. Circulation. 102:584-90
Abriel et al. 2001. Circ. Res. 88:740-5
Rivolta et al. 2001. JBC. 276(33):30623-30630
WT Simulation
Veldkamp et al. 2000. Circ. Res. 86:e91-97
Supplemental Figure 1
P2/
P1
P1-P2 interval (ms)
A
B
C
D
E
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
1 10 100 1000
Kambouris et al. 2000. JCI. 105:1133-40
F
WT
WT
WT
WT
WT
Recovery time (ms)
WT simulation
Chandra, Starmer and Grant. 1998. AJP. 274. H1643-54.
See also Rook et.al. 1999. Cardiovascular Res. 44. 507-17
Makita et. al. 2000. Circulation. 101:54-60.
Rivolta et. al. 2001. JBC. 30623-30630.
Membrane potential (mV)
-120 -80 -40 0
0
0.2
0.4
0.6
0.8
1A
vaila
bilit
y/co
nduc
tanc
e
Supplemental Figure 2
A
B
C
D
Abriel et. al. 2001. Circ. Res. 88:740-45.
Wehrens et. al. 2000. Circulation. 102:584-590.
WT
WT
WT
availabilityactivation
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