Wednesday 06 May 2015 - EMBL Heidelberg · DNA methylation profile of sporadic and melanoma-prone...
Transcript of Wednesday 06 May 2015 - EMBL Heidelberg · DNA methylation profile of sporadic and melanoma-prone...
Programme
Wednesday 06 May 2015 15:00 - 17:15 Arrival and Registration
ATC Reception
17:15 - 17:30 Opening remarks ATC Auditorium
17:30 - 20:10 Session 1: Transgenerational inheritance Chairs: Asifa Akhtar and Renato Paro ATC Auditorium
17:30 - 17:55 Propagating transcription patterns through mitosis 1Gerd Blobel Children's Hospital of Philadelphia, United States of America
17:55 - 18:10 Transmission and accurate deployment of human Chromosome 21 through the mouse male germline
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Christina Ernst Cancer Research UK - Cambridge Institute, United Kingdom
18:10 - 18:35 Demystifying trans-generational epigenetics 3Vincent Colot École Normale Supérieure, France
18:35 - 19:05 Coffee Break ATC Foyer
19:05 - 19:30 Spatial distribution of H3K9 methylated chromatin in worm embryos: fate decisions in development
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Susan M. Gasser Friedrich Miescher Institute for Biomedical Research, Switzerland
19:30 - 19:45 Sperm is epigenetically programmed to regulate gene transcription in embryos
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Jerome Jullien Cambridge University, United Kingdom
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EMBO Conference: Chromatin and Epigenetics
19:45 - 20:10 Chromatin replication and epigenome maintenance 6Anja Groth BRIC, University of Copenhagen, Denmark
20:10 - 22:00 Welcome Reception in the ATC Foyer and Rooftop Lounge
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Programme
Thursday 07 May 2015 09:00 - 12:10 Session 2: Systems biology in epigenetics
Chairs: Sarah Teichmann and Vincent Colot ATC Auditorium
09:00 - 09:25 Genome regulation during embryonic development 7Eileen Furlong EMBL Heidelberg, Germany
09:25 - 09:40 Genomic and epigenomic determinants of mammalian DNA methylation patterns
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Tuncay BaubecFriedrich Miescher Institute for Biomedical Research, Switzerland
09:40 - 09:55 High resolution chromatin dynamics during a yeast stress response
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Nir Friedman The Hebrew University of Jerusalem, Israel
09:55 - 10:20 Toward physical principles of chromatin (re)organization 10
Leonid Mirny
Massachusetts Institute of Technology, United States of America
10:20 - 10:50 Coffee Break ATC Foyer
10:50 - 11:15 Unraveling principles of chromatin regulation using massively parallel measurements of designed sequences
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Eran Segal
Weizmann Institute of Science, Israel
11:15 - 11:30 Enhancer – core-promoter specificity separates developmental and housekeeping gene regulation
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Cosmas ArnoldIMP, Austria
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EMBO Conference: Chromatin and Epigenetics
11:30 - 11:45 Proteins that bind regulatory regions in the embryonic stem cell genome, identified by histone-modification chromatin immunoprecipitations and mass spectrometry
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Raymond Poot Erasmus MC, The Netherlands
11:45 - 12:10 To be presented onsite 14John Stamatoyannopoulos University of Washington, United States of America
12:10 - 13:30 Lunch ATC Foyer
13:30 - 16:00 Poster Session I
ATC Helices
16:00 - 18:55 Session 3: The chromatin proteomeChairs: Susan Gasser and Michiel Vermeulen ATC Auditorium
16:00 - 16:25 Quantitative interaction proteomics for epigenetics 15Michiel VermeulenRadboud University Nijmegen, The Netherlands
16:25 - 16:40 Posttranslational modifications on the histone variant CENP-A/ Cse4 from S. cerevisiae
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Ann Ehrenhofer-MurrayHumboldt-Universität zu Berlin, Germany
16:40 - 17:25 Coffee Break & Meet the SpeakersATC Foyer
17:25 - 17:50 Dynamics and regulation of DNA methylation in mouse development
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Michaël Weber University of Strasbourg/CNRS, France
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Programme
17:50 - 18:15 Chromatin architecture and dynamics of histone variant H2A.Z at yeast promoters
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Carl Wu HHMI, Janelia Research Campus, United States of America
18:15 - 18:30 CRISPR/Cas9 deletion shows that HBO1 is essential for H3K14 acetylation in human cells
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Anne Voss Walter and Eliza Hall Institute of Medical Research, Australia
18:30 - 18:55 Integrative structural analysis of the INO80 chromatin remodeler
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Karl-Peter HopfnerLMU Munich, Germany
18:55 - 21:00 Dinner ATC Canteen
21:00 - 22:30 After dinner drinks in the ATC Foyer and Rooftop Lounge
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EMBO Conference: Chromatin and Epigenetics
Friday 08 May 2015 09:00 - 12:05 Session 4: Chromatin dynamics, signalling and disease
Chairs: Geneviève Almouzni and Paolo Sassone-Corsi ATC Auditorium
09:00 - 09:25 Non-coding upstream anti-sense promoters are distinct hubs of transcription factor binding and enhancer-like histone modifications
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Karen Adelman NIEHS/ NIH, United States of America
09:25 - 09:40 Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions
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Darío G. Lupiáñez MPI for Molecular Genetics, Germany
09:40 - 09:55 Programmed reorganization of telomeres triggered by mitochondrial activity in long-lived quiescent cells
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Angela Taddei Institut Curie, France
09:55 - 10:20 Parental origin effects and the epigenetic control of developmental processes
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Anne Ferguson-Smith University of Cambridge, United Kingdom
10:20 - 11:00 Coffee Break & Meet the SpeakersATC Foyer
11:00 - 11:25 Common threads: epigenetics, metabolism and the clock 25
Paolo Sassone-Corsi
University of California, Irvine, United States of America
11:25 - 11:40 Epigenetic regulation and chromatin dynamics in embryonic stem cells and cancer
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Raffaella SantoroUniversity of Zurich, Switzerland
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Programme
11:40 - 12:05 Actin-related proteins and regulatory domains enable nucleosome ejection by RSC/Sth1
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Bradley Cairns University of Utah, United States of America
12:05 - 13:30 Lunch ATC Foyer
13:30 - 16:00 Poster Session II ATC Helices
16:00 - 17:00 Session 5: Keynote lecture: Renato Paro Chair: Robert Kingston ATC Auditorium
16:00 - 17:00 Cellular memory in regeneration and cancer 28Renato Paro ETH Zurich, Switzerland
17:00 Free Evening
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EMBO Conference: Chromatin and Epigenetics
Saturday 09 May 2015 09:00 - 11:45 Session 6: RNA and epigenetics
Chairs: Anne Ferguson-Smith and Edith Heard ATC Auditorium
09:00 - 09:15 Systematic characterization of the KRAB zinc finger proteins family using high-resolution ChIP-Seq 154Michael Imbeault EPFL, Switzerland
09:15 - 09:30 Disentangling the Xist regulatory network 30Edda Schulz MPI for Molecular Genetics, Germany
09:30 - 09:45 Single-cell mass cytometry of gene regulatory networks in highly complex samples
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Andreas Frei Stanford University, United States of America
09:45 - 10:10 Epigenetic regulation by MOF containing complexes 32Asifa Akhtar MPI of Immunobiology and Epigenetics, Germany
10:10 - 10:50 Coffee Break ATC Foyer
10:50 - 11:15 Chromatin determinants of centromeric identity and their deregulation in cancer
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Geneviève AlmouzniInstitut Curie/CNRS, France
11:15 - 11:30 A new epigenetic twist: LncRNAs target chromatin by triple helix formation
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Holger Bierhoff German Cancer Research Center, DKFZ-ZMBH Alliance, Germany
11:30 - 11:45 Global chromatin regulation effects molecular features of totipotent cells
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Maria-Elena Torres-Padilla IGBMC, France
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Programme
11:45 - 13:30 Lunch ATC Canteen
13:30 - 16:00 Poster Session III ATC Helices
16:00 - 19:10 Session 7: Nuclear architecture and chromatin structure Chairs: Bas van Steensel and Bradley Cairns
ATC Auditorium
16:00 - 16:25 X-chromosome inactivation: exploring the relationship between chromosome structure and gene activity
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Edith Heard Institut Curie, France
16:25 - 16:40 In vitro reconstitution of NFR-array nucleosome patterns across the yeast genome with purified remodelers and barrier factors
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Philipp Korber University of Munich, Germany
16:40 - 16:55 Chromatin dynamics during mouse oogenesis 38Petra Hajkova MRC Clinical Sciences Centre, United Kingdom
16:55 - 17:20 Polycomb-Group function: compaction of nucleosomes and regulation by lncRNAs
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Robert Kingston Massachusetts General Hospital, United States of America
17:20 - 18:05 Coffee Break & Meet the SpeakersATC Foyer
18:05 - 18:30 Novel, ligation-free method for identifying chromatin interactions genome-wide
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Ana Pombo Max-Delbrück-Centre for Molecular Medicine, Germany
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EMBO Conference: Chromatin and Epigenetics
18:30 - 18:45 Histone H2B methylation – a novel guardian of transposable elements
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Robert Schneider IGBMC, France
18:45 - 19:10 Function and regulation of long-distance chromosomal interactions
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Francois Spitz EMBL Heidelberg, Germany
19:10 - 19:15 Poster Prize AnnouncementATC Auditorium
19:15 - 00:30 Banquet Dinner and Party ATC Canteen and ATC Foyer
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Programme
Sunday 10 May 2015 09:00 - 11:45 Session 8: New technologies in epigenomics
Chairs: Ana Pombo and Davide Corona ATC Auditorium
09:00 - 09:25 Expression homeostasis during DNA replication 43Naama Barkai Weizmann Institute of Science, Israel
09:25 - 09:50 Chromatin status and stochasticity in gene expression 44Sarah Teichmann EMBL-EBI and Wellcome Trust Sanger Institute, United Kingdom
09:50 - 10:05 Structure and Dynamics of Replication Domains in Single Chromosome Territories of Interphase Nuclei
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Wanqing XiangEMBL Heidelberg, Germany
10:05 - 10:20 Poster prize talk 1ATC Auditorium
10:20 - 10:50 Coffee Break ATC Foyer
10:50 - 11:05 Poster prize talk 2 ATC Auditorium
11:05 - 11:20 Poster prize talk 3 ATC Auditorium
11:20 - 11:45 Mapping of genome – nuclear lamina interactions in single cells
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Bas van Steensel Netherlands Cancer Institute, The Netherlands
11:45 - 12:00 Closing remarks ATC Auditorium
12:00 - 12:30 Packed lunch and departureATC Foyer
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EMBO Conference: Chromatin and Epigenetics
Poster removal (Please remember to collect your poster. Posters which have not been collected will be disposed of after the meeting.)
Feedback Questionnaire - Check your inbox when the meeting ends! You will find an email with the link to the online feedback questionnaire. Please take time to complete it!
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Posters A-Z
Agresti, Alessandra Nucleosomal landscapes in nucleosome-rich and nucleosome-poor cells
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Ahmad Zabidi, Muhammad Mamduh binEnhancer–core-promoter specificity in housekeeping and developmental transcriptional regulation
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Alabert, ConstanceTwo distinct modes for propagation of histone PTMs across the cell cycle
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Alex, Tina Poly ADP-ribose polymerase1 ortholog in Dictyostelium discoideum regulates its growth and development
50
Amort, Thomas Identification and characterization of cytosine methylation in mammalian lncRNAs
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Andersson, AnneliH2O2-induced chromatin-associated poly-ADP-ribosylation is dependent on PKCa mediated phosphorylation of HMGB1
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Araújo, Érica Sara Souza de DNA methylation profile of sporadic and melanoma-prone patients 53
Arner, Erik Enhancers lead waves of coordinated transcription in transitioning mammalian cells
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Artemov, Artem Single-cell gene expression pattern might reflect topological organization of the genome
55
Attig, Jan The splicing regulator Matr3 suppresses alternative exons in long introns marked by H3K36 tri-methylation
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Auclair, Ghislain Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse
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EMBO Conference: Chromatin and Epigenetics
Azami, Sina Study of expression and methylation of SFRP4 gene in 30 colorectal cancer patients
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Babl, Virginia Chromatin dynamics at the yeast rDNA locus upon transition to and exit from stationary phase
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Ballarino, Monica Presenter: Cipriano, Andrea The long non-coding RNA lnc-405 is a nuclear transcript which promotes myoblasts differentiation
60
Bardet, Anaïs F. Transcription factor sensitivity to DNA methylation 61
Basson, Albert The chromatin remodeller CHD7 controls cerebellar growth via Reelin 62
Bauer, Fanelie Functional analysis of H3K79 methylation 63
Begni, Veronica Telomere length: Role of the effect of stress on psychiatric disorders vulnerability and on its transgenerational transmission
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Beira, Jorge V. Interplay between signaling and chromatin during regeneration and tumourigenesis
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Belikov, Sergey Quantitative analysis of transcription factor-DNA interactions in vivo 66
Bellvis, Pablo Role of histone mutations in brain tumors 67
Bender, Ambre Deciphering the role of DNA methylation in the ontogeny of hematopoietic stem cells in the mouse embryo
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Posters A-Z
Bengtsen, Mads Identification of c-Myb binding sites by DNase I footprinting in six hematopoietic cell types
69
Bernhart, Stephan H. Does disturbance of poised chromatin cause cancer? 70
Bhattacharya, Saikat A structural and functional study of the role of H2A isoforms H2A.1 and H2A.2 in cancer
71
Bodega, Beatrice Epigenetic control of L1 retrotransposition in skeletal muscle differentiation
72
Boeckmann, Lars Novel role of Dbf4-Dependent Kinase in ubiquitin-dependent proteolysis of Cse4/CENPA in S. cerevisiae
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Borgel, Julie Presenter: Bartke, Till A function for the lysine demethylase KDM2A in histone modification-independent HP1 recruitment and cell proliferation
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Borggrefe, Tilman Presenter: Giaimo, Benedetto DanieleA phospho-dependent mechanism controls a committed chromatin state at Notch target genes
75
Bou Dargham, Daria Genome-wide analysis of ATP-dependent chromatin remodeling factors functions in embryonic stem cells and during differentiation
76
Bracken, Adrian Identification of a novel protein, ‘BIG’, which links Polycomb gene repression and nuclear receptor signalling
77
Brauchle, Eva Molecular epigenetic signature of pluripotent embryonic stem cells 78
Brauns-Schubert, Prisca The histone acetyl transferase Tip60 is regulated by phosphorylation 79
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EMBO Conference: Chromatin and Epigenetics
Breiling, Achim Tet1 and Tet2 protect DNA methylation canyons against hypermethylation
80
Bright David, Starling Emerald Early indicators of altered metabolic function 81
Bystricky, Kerstin macroH2A1.1, an actor in the maintenance of a transient cellular state in EMT progress towards metastatic development of breast tumors
82
Bystricky, Kerstin Chromatin folding in estrogen regulated transcription 83
Cardoso-Júnior, Carlos Evidence of epigenetic modifications in DNA and histones of the stingless bee Melipona scutellaris and implications in caste differentiation
84
Cebrià Costa, Joan Pau Characterization of oxidized H3 as a new histone modification 85
Chabbert, Christophe Presenter: Pelechano, Vicent; Chabbert, Christophe; Adjalley, Sophie H.
A high-throughput ChIP-Seq for large-scale chromatin studies 86
Chao, Yu-Chan Baculovirus IE2, a master viral factor to locate the invading viral genome, manage gene activation, and result viral genome replication
87
Chatterjee, Anamika Does cryopreservation alter the epigenetic properties of stem cells? 88
Chen, Chun-ChangDNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases
89
Chen, Shuting The functional role of RAI1 in retinoic acid signaling 90
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Posters A-Z
Chen, Xi Enhancer commissioning by the transcription factor complex IRF-BATF during CD4+ T cell differentiation
91
Chung, Ho-Ryun The tale of two tails 92
Coda, Davide Martino Signalling to the epigenome: how TGF-ß superfamily ligands regulate gene expression via chromatin
93
Cortesi, Alice D4Z4 repeat regulates transcriptional units in trans via chromosome looping
94
Dalcher, Damian The role of the epigenetic factor TIP5 in embryonic stem cells 95
Darr, Jonatan A novel mechanism for Swi/Snf mediated transformation in Ewing's Sarcoma
96
Declerck, Ken Epigenetic control of cardiovascular health by diet or cocoa flavanol metabolites involves multiple chromatin writer-eraser enzymes
97
Defossez, Pierre-Antoine A histone mimic within DNA Ligase 1 recruits UHRF1 to sites of DNA replication: implications for DNA remethylation
98
Denizot, Jeremy Presenter: Petrini, Edoardo Chromatin-remodeling factor SMARCAD1 regulates tissue-specific and innate-immunity linked gene expression by organizing chromatin over CpG islands in intestinal cells
99
Dillinger, Stefan Molecular mapping of nucleolus-associated chromosomal domain dynamics during cellular senescence
100
Dimond, Andrew Developmental gene promoters establish poised enhancer loops in embryonic stem cells
101
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EMBO Conference: Chromatin and Epigenetics
Ding, Pingtao Transcriptional regulation in effector-triggered immunity via NB-LRR resistance genes RPS4 and RRS1
102
Domke, Tanja O-GlcNAc: an evolving role in transcriptional regulation in mouse embryonic stem cells
103
Droog, Marjolein Comparative genomics identifies a distinct DNA-binding signature of ERa in tamoxifen-associated endometrial cancers
104
Du, Chunguang Integrated network analysis of maize endosperm epigenomics 105
Duffy, Michael F. A novel Plasmodium Falciparum bromodomain protein regulates invasion gene expression
106
Elizar'ev, Pavel Studying PREs/TREs activity switch in Drosophila 107
El-Osta, Assam Presenter: Khurana, Ishant Methylome sequencing identifies CTCF regulated genes implicated in diabetic complications
108
Eom, Gwang Hyeon Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy
109
Eom, Gwang Hyeon PP2A/HSP70 dynamically regulates HDAC2 phosphorylation and its activity in cardiac hypertrophy
110
Falcao, Ana Peptidylarginine deiminases as regulators of the epigenetic state of oligodendrocyte precursor cells
111
Feng, Weijun The chromatin remodeller CHD7 is essential for neurogenesis and tumorigenesis
112
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Posters A-Z
Fennessy, Ross T. Genome-wide mapping of nascent chromatin provides evidence for distinct replication and transcription coupled pathways for nucleosome organisation
113
Festenstein, Richard Presenter: Law, Pui-Pik Interplay between histone variant H3.3 and Heterochromatin protein 1 gamma (HP1?) in gene regulation genome wide in mice
114
Festenstein, Richard Position Effect Variegation as a model for DNA-repeat diseases and epigenetic memory: a novel therapy for an incurable disease?
115
Fischer, Johanna Investigating the role of conserved non-coding elements in determining DNA toplogy
116
Förderer, Alexander The functional divergence of plant SET domain histone methyltransferases
117
Frommel, Sandra C. BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
118
Gaarenstroom, Tessa Gene expression dynamics in response to TGF-ß signalling through Smad2-mediated transcription
119
Gagliardi, Miriam ICF-specific DNMT3B mutations affect the intragenic epigenetic signature interfering with the control of splicing events
120
Gaillard, Marie-Cécile 3D nuclear topology dynamics of the 4q35 subtelomeric region linked to Facio-Scapulo-Humeral Dystrophy in skeletal muscle cells and hIPSC
121
Gainetdinov, Ildar Epigenetic regulation of PIWIL2 in testicular germ cell tumors and its diagnostic implications
122
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EMBO Conference: Chromatin and Epigenetics
Galle, Joerg Presenter: Rother, Karen Hypomethylating agent-based therapy: Insights from in silico simulations
123
Garding, Angela Identifying Novel Transcription Factors Underlying Neurogenesis 124
Georgieva, Angelina Linking high order chromatin reorganization to stem cell homeostasis by H3K56ac and Sirt6
125
Ghosh, Shrestha Regulation of SIRT6 activities by the Lamins 126
Giorgetti, Luca Polymer modeling of Hi-C data reveals genome-wide correlations between chromosome structure and local chromatin state
127
Givaty Rapp, Yemima Open chromatin conformation in dedifferentiating cells is associated with activation of S1 type endonucleases
128
Gnani, Daniela Possible functional cross-talk between FAK and EZH2 in intra-hepatic lipid accumulation
129
Gómez Velázquez, Melisa Regulation of genome architecture during heart development 130
Grimaldi, Alexis Chromatin type comparison at differential TADs 131
Grimm, Christina Epigenetic alterations in intestinal tumor formation in men and the Apc(Min/+) mouse model
132
Griñán-Ferré, Christian Time course screening of miRNAs in female SAMP8: Implications in senescence process
133
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Posters A-Z
Groth, Martin Synergistic roles of SU(VAR)3-9-RELATED2 and SNF2 family proteins FRG1 and 2 in RNA-directed DNA methylation in Arabidopsis
134
Groves-Kirkby, Nick Parent of origin effects on gene expression in human twins 135
Grundström, Thomas Signal regulated localisation of a mutagenic protein complex at the Igh locus
136
Gu, Namjin Analysis of transcriptome and epi-genomic data for endothelial progenitor cell differentiation
137
Halsall, John Histone deacetylase inhibitors initiate a transcriptional and Polycomb-mediated, chromatin-based response that promotes cell survival
138
Hansel-Hertsch, Robert G-quadruplex structure formation is prevalent in chromatin regulatory elements and is elevated during oncogenesis
139
Hayano, Motoshi Evidence for an epigenetic cause of aging in mice 140
Heery, David M. A twist in the tail for chromatin modification: Molecular basis of MOZ/KAT6A function as a histone PTM reader/writer
141
Heinz, Helena Presenter: Horsthemke, Bernhard Development of an inducible cell culture model for transcriptional interference at the Angelman syndrome gene UBE3A
142
Hennion, Magali Decoding the engram: A deep look into the epigenetics of learning and memory
143
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EMBO Conference: Chromatin and Epigenetics
Hernando Herraez, Irene A genome-wide comparative study of DNA methylation in Great Apes 144
Hoeijmakers, Wieteke Dissecting the Plasmodium falciparum epigenome by Mass-Spectrometry-based Proteomics
145
Hoelper, Dominik Role of the histone chaperone Daxx in proviral silencing via interaction with SETDB1
146
Hoffman, Michael M. Transcription factor motif discovery and prediction in an expanded epigenetic alphabet
147
Hoffmann, Christian Presenter: Neumann, Heinz In vivo mapping of FACT-histone interactions identifies a role of Pob3 C-terminal domain in DNA replication
148
Hore, Tim Presenter: Iurlaro, Mario Epiblast stem cells as a system for the study of DNA demethylation function in reprogramming
149
Hottiger, Michael O. ADP-ribosylation of histones: A reversible modification of specific amino acid residues
150
Hur, Man-Wook ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65
151
Hussong, MichelleThe bromodomain protein BRD4 regulates splicing during the heat shock response
152
Ievolella, Monica Investigating KRAB/KAP1-mediated epigenetic control of differentiation and function of the adaptive immune system
153
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Posters A-Z
Imbeault, Michael Systematic characterization of the KRAB zinc finger proteins family using high-resolution ChIP-Seq
154
Iturbide Martínez de Albéniz, Ane LOXL2 oxidizes methylated TAF10 and controls neural progenitor differentiation
155
Jägle, Sabine Silencing of the EPHB3 tumor suppressor involves multimodal decommissioning of a transcriptional enhancer by defective Notch signaling and the EMT inducer SNAIL1
156
Jang, Suk Min Role of KAP1 during DNA replication 157
Javierre, Biola M. High-resolution analysis of genomic regulatory architecture in multiple human cell types with Promoter-Capture HiC
158
Jeon, Bu-Nam KR-POK has tumor progressive activity and regulates cancer cell proliferation through glutamine metabolism
159
Jha, Sudhakar Investigating TIP60’s role in regulating cancer metastasis 160
Jost, Daniel Modeling epigenetic regulation: implications to development, proliferation and diseases
161
Jost, Daniel Interactions between chromatin states shape the epigenome nuclear organization
162
Kalasova, Ilona Nuclear phosphatidylinositol 4-phosphate affects the activity of lysine-specific histone demethylase 1
163
Kamminga, Leonie M. Normal formation of the vertebrate body plan and loss of cardiac integrity in the absence of ezh2
164
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EMBO Conference: Chromatin and Epigenetics
Kanki, Yasuharu Angiogenesis is regulated by trithorax complex in solid tumor 165
Kar, Gozde Deciphering the relationship between chromatin status and stochasticity in gene expression from single-cell RNA-seq data
166
Katou, Yuki RNA dependent protein binding revealed by ChIP-seq 167
Khurana, Ishant Methylome sequencing identifies CTCF regulated genes implicated in diabetic complications
168
Kleinmanns, Julia Anna Functional characterization of BLISTER - A Polycomb group associated protein in Arabidopsis
169
Koh, Dong-In c-Myc decides cell fate through ZBTB5 170
Kokkalis, Antonis Genome-wide characterization of the role of macroH2A histone variants in cellular differentiation and reprogramming
171
Kook, Hyun Presenter: Joung, Hosouk Ret finger protein mediates Pax7-induced ubiquitination of MyoD in skeletal muscle atrophy
172
Krasikova, Alla Endoreplication and selective elimination of parental genomes during oogenesis in hybrid European water frogs
173
Kretzmer, Helene Fast and memory efficient DMR calling 174
Kriukiene, Edita Methyltransferase-directed enzymatic exchange and genomic mapping of cytosine-5 modification at single base resolution
175
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Posters A-Z
Kruse, Kai Changes in the network of chromatin contacts during the P. falciparum infection cycle
176
Kumar, Mukesh Presenter: Vastenhouw, Nadine L. Histone level determines the timing of zygotic genome activation in zebrafish
177
Kungulovski, Goran Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained
178
Laktionov, Petr Hierarchic model for selective activation of testis-specific genes in D. melanogaster
179
Lan, Wanwen Involvement of novel non-coding RNA in pterygium cell proliferation 180
Lanzuolo, Chiara The epigenetic role of Lamin A in muscle differentiation 181
Lee, Jong-Soo A novel mitotic role of HP1 182
Leone, Sergio RNA helicases are implicated in lncRNA-mediated epigenetic silencing 183
Lerdrup, Mads An interactive environment for agile mining and visualization of ChIP-sequencing data
184
Lesniak, Wieslawa Analysis of cytosine methylation within selected regions of the Epidermal Differentiation Complex (EDC) during keratinocyte differentiation
185
Li, Jinghua Analysis of chromatin states at Notch regulated genes reveals large scale changes in H3K56 acetylation accompany enhancer activation
186
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EMBO Conference: Chromatin and Epigenetics
Lim, Ji Hyae Identification of Fetal-Specific Epigenetic Markers on Chromosome 21 for non-invasive prenatal testing of fetal trisomy 21
187
Liokatis, Stamatios Independent observation of sister histones and readout of asymmetric post-translational modification (PTM) patterns in nucleosomes by high-resolution Nuclear Magnetic Resonance (NMR) spectroscopy
188
Lopizzo, Nicola GR and GR-target genes: epigenetic modulation in response to gene-environment interaction in psychiatric disorders
189
Lüscher, Bernhard Ash2l, a core component of MLL histone methyltransferase complexes, is essential for histone H3 lysine 4 methylation and cell proliferation
190
MacCarthy, CaitlinDissecting Oct4's DNA contacts in establishing and maintenance of pluripotency
191
Mahé, Elise Understanding the role of 5-hydroxymethylcytosine at active enhancers during cell differentiation
192
Maksimenko, Oksana Domain organization of CTCF protein in Drosophila melanogaster 193
Maqbool, Muhammad Ahmad Combinatorial Enhancer usage influences tuning of gene expression and isoform selection during T-cell differentiation
194
Marasca, Federica A dynamic switch of Ezh1 isoforms controls PRC2 mediated adaptive epigenetic response in post-mitotic cells
195
Marasek, Pavel Paxillin interacts with cohesin and regulates the expression of IGF2/H19 gene cluster
196
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Posters A-Z
Markozashvili, Diana Study of HDAC Inhibitor Abexinostat in Mantle Cell Lymphoma 197
Marsman, Judith Cohesin and CTCF contact regulatory elements to control runx1 expression
198
Marullo, Fabrizia Role of LaminA/C-PcG proteins crosstalk in Hutchinson-Gilford Progeria syndrome
199
Mayer, Andreas Visualizing human transcription with nucleotide resolution by native elongating transcript sequencing
200
McMurchy, Alicia N. The role of nucleosome remodeler MI-2/LET-418 in the germline-soma distinction in C. elegans
201
Meister, Peter Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans
202
Miklik, Dalibor Epigenetic environment in the integration site-specific regulation of retroviral transcription
203
Miron Sardiello, Ezequiel J. Novel CRISPR modality for versatile super-resolution chromatin imaging 204
Moissiard, Guillaume Presenter: Yen, Linda Arabidopsis thaliana microrchidia homologues regulate gene silencing 205
Mokhtari, Zakia Internal dynamics of a living cell nucleus: Study by Dynamic light scattering
206
Möller, Mareike The impact of histone methylation on genome stability in experimental evolution in Zymoseptoria tritici
207
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EMBO Conference: Chromatin and Epigenetics
Mondin, Mateus Chromatin dynamics of the 45S rDNA arrays and their relationship to epigenetic indexing
208
Montes, Matias In vivo and in vitro complex formation analysis on Schizosaccharomyces pombe HomolD box-containing promoters
209
Montibus, Bertille Bivalent chromatin signature is the default state of imprinting control regions (ICRs)
210
Muchardt, Christian A role for HP1 proteins in normal and pathological control of inflammation
211
Mueller, Britta MNase titration reveals changes in chromatin accessibility during the unfolded protein response
212
Müller, Sebastian HJURP, a histone chaperone bridging the nucleosomal scale to a chromosome landmark
213
Mushunje, Annals T. Epigenetic regulation of transcription of the stevor multigene family of Plasmodium falciparum
214
Mutazono, Masatoshi Regulation of RNAi-mediated formation of centromeric heterochromatin through ncRNA and the splicing machinery in fission yeast
215
Namdeo, Suryesh K. A long non coding RNA acts as a potential regulator of mouth form developmental plasticity of Pristionchus pacificus.
216
Nardocci, Gino Epigenetic control of osteoblast lineage commitment through regulating Runx2/p57 gene transcription
217
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Posters A-Z
Nashun, Buhe Continuous histone H3.3/H4 replacement by Hira is essential for normal transcriptional regulation and efficient de novo DNA methylation during mouse oogenesis
218
Navratilova, Pavla Complex epigenomes of endocycling ovaries vs. mitotic testis in the closest living relative of vertebrates
219
Neri, Francesco Single-base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals DNA methylation/demethylation dynamics in the mammalian genome
220
Nicodemi, Mario Presenter: Fraser, James Hierarchical organization of chromosome folding during mammalian cell differentiation
221
Nishibuchi, Gohei Phosphorylation of HP1alpha regulates its function in chromatin organization
222
Nowak, Theresa Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and peptide-based inhibitors
223
Ori, Alessandro Histone deacetylase inhibitors cause the selective depletion of bromodomain containing proteins
224
Ozturk, Nail Can Early Cranial Irradiation Alters Epigenetic Profile of Hippocampal Neurogenesis
225
Palacios, Daniela Presenter: Brancaccio, Arianna Post-translational control of EZH2 stability via phospho-ubiquitination regulates skeletal myogenesis
226
Pan, Leslie Role of topological domains in organizing remote regulatory interactions 227
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EMBO Conference: Chromatin and Epigenetics
Papamichos-Chronakis, Manolis INO80 remodeler facilitates release of RNA Polymerase II from chromatin for ubiquitin-proteasomal degradation
228
Park, Seongjin Prometheus: Omics portal for comparative genomics 229
Pasumarthy, Kalyan Kumar Methylation dynamics at genic and non-genic functional elements across the genome in Mesenchymal stem cells
230
Petrini, Edoardo Transcriptional regulation during phosphate starvation requires Myosin I in fission yeast
231
Picchi, Gisele Chromatin-modifying enzymes in T. cruzi 232
Pieters, Bas Exploration of the chemical basis behind the recognition of the epigenetic H3K4me3 mark
233
Piwko, Pawel Gypsy insulator containing transgenes display transvection 234
Popov, Sergej The Epstein-Barr virus nuclear antigen 1 – a link between chromatin organization and genomic instability in viral oncogenesis
235
Popp, Christian Role of histone variants H3.3 and H2A.Z in epigenetic memory in induced pluripotent stem cells
236
Porter, Keith The role of chromatin remodeling factor SMARCAD1 in intestinal intraepithelial lymphocyte homeostasis
237
Postepska-Igielska, Anna Functional interplay between sense and antisense RNA: lncRNA Khps1 mediates changes of the chromatin structure and regulates expression of the proto-oncogene SPHK1
238
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Posters A-Z
Prasad, Punit CAGE deep-sequencing identifies epigenetic regulators in human blood cell types
239
Qi, Hui Epigenetic control of cardiopulmonary development and congenital heart disease
240
Radman-Livaja, Marta Nucleosome repositioning during DNA replication 241
Ramírez, Fidel Topologically associating domain boundaries serve as recruitment platforms for the Drosophila dosage compensation complex
242
Rezsohazy, Rene Ogt and Prdm14 are direct interactors of the Hoxa1 homeoprotein 243
Ricci, Barbara A novel Polycomb feed forward loop in glioblastoma multiforme 244
Roche, Stephane DNA Methylation-based diagnosis of Facio Scapulo Humeral Dystrophy 245
Rokach, Ori Epigenetic changes as a common trigger of muscle weakness in congenital myopathies
246
Sadeghi, Laia Paf1 complex factor Leo1 promotes local nucleosome turnover to alter chromatin state in fission yeast
247
Sahlen, Pelin Akan Genome-wide mapping of promoter-anchored interactions at a single enhancer resolution
248
Schumacher, Eva Epigenetic changes during in vitro activation of hepatic stellate cells 249
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EMBO Conference: Chromatin and Epigenetics
Schunter, Sarah The impact of MOF ubiquitylation on Drosophila Dosage Compensation 250
Schutkowski, Mike Presenter: Eckey, Maren Advanced characterization of histone-code directed antibodies 251
Schutkowski, Mike A direct and continuous Sirtuin activity assay 252
Seiser, Christian H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress
253
SeongHui, Eo De-methylation Inducer, 5’-azacytidine Regulates Dedifferentiation and Inflammation via p38 kinase in Rabbit Articular Chondrocytes
254
Serobyan, Vahan Epigenetic regulation of a developmental switch gene 255
Shaik, Tajith Baba Study of Schistosoma mansoni HDAC8, a key epigenetic player in the treatment of Schistosomiasis
256
Shekariesfahlan, Azam S-nitrosylation of arabidopsis nuclear proteins, specially its plant specific histone deacetylases (HD2 like proteins)
257
Shliaha, Pavel Towards top-down proteomics: Sequencing intact histones by mass spectrometry for precision mapping of co-occurring post-translational modifications
258
Shlyueva, Daria Genome-wide maps of enhancers downstream of WNT and hormone signaling
259
Shumskaya, Valeria Influence of osmotic stress on the epigenetic changes during the induction of pluripotent stem cells from somatic cells
260
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Posters A-Z
Sigurdsson, Stefan Promoter methylation of DNA repair genes in cancer 261
Singh, Vijender The encounter of RNA polymerase with stable nucleosomes facilitates transitions in elongation coupled processes
262
Smigova, Jana Structural basis of the Polycomb body 263
Sobol, Margarita A.PIP2 islets – a novel compartment of the cell nucleus 264
Sokolov, Alexey SVMOneClAS: pipeline for efficient splicing events calling 265
Soldi, Monica Dynamic profiling of chromatome at enhancers of inflammatory genes 266
Soupsana, Aikaterini Chromatin remodelling during stem cell differentiation proceeds through a process resembling a "shifting mosaic steady-state"
267
Stanley, Alice The dynamics of cohesin-mediated cis-regulatory modules reveal interplay with transcription factors
268
Stelloo, Suzan Androgen Receptor profiling in tumor specimens yields hallmarks of prostate cancer outcome
269
Stempor, Przemyslaw SeqPlots - a fast interactive web tool for visualizing next generation sequencing signals along genomic features
270
Stewart, KathleenDNA Methylation-Histone Modification Crosstalk During de novo DNA Methylation
271
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EMBO Conference: Chromatin and Epigenetics
Stratigi, Kalliopi Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression
272
Strømme, Caroline B. Structure-function insights into MCM2 chaperoning of H3/H4 tetramers and, with ASF1, H3/H4 dimers
273
Taddei, Angela Presenter: Tadeo, Xavier Replicative stress links to heterochromatic silencing 274
Tercan Avci, Sanem A novel mechanism for the regulation of H3K27me3 modification in hepatocellular carcinoma cell line Huh7
275
Thomas, Tim Moz (Kat6a) haploinsufficiency dramatically retards MYC-induced lymphoma development
276
Timmermans, Steven Finding new miR-target relationships using the SPRET/Ei mouse strain 277
Tolic, Anja Regulation of Cxcl12 gene transcription by DNA methylation 278
Tu, WenJuan Characterizing epigenetic signatures that mark transcriptional memory responsive genes in human T lymphocytes
279
Tzerpos, Petros Convergent roles of transcription factors BACH1 and SATB1 in murine Tcells
280
Ugarte, Fernando Presenter: Krietsch, Jana Progressive chromatin condensation and H3K9 methylation regulate the differentiation of hematopoietic stem cells
281
Ulicna, Livia PHF8 histone demethylase interacts directly with nuclear phosphatidylinositol-4,5-bisphosphate
282
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Posters A-Z
Vaillant, Isabelle Bivalency is a key component of the regulation of imprinted genes expression during neural differentiation
283
van den Berg, Debbie LC A novel Ascl1-interacting factor regulates cortical neurogenesis 284
van Zundert, Brigitte AJ Bi-directional transcriptional and epigenetic modulation of endogenous PSD95 gene expression to regulate neuronal refinement
285
Villa, Raffaella Targeting of the Drosophila dosage compensation complex relies on specific DNA recognition by MSL2
286
Vollenweider, Eva PARP1-mediated parylation orchestrates the dynamics of heterochromatin assembly during replication
287
Wang, Sai Dependence of chromatin structure on histone modification, linker histone, and nucleosome repeat length
288
Ward, Aoife Global identification of genomic loci bound by epigenetic protein complexes
289
Westermark, Pål Characterization of the circadian core promoter 290
Whongsiri, Patcharawalai Oxidative stress and RUNX3 hypermethylation in chronic hepatitis B-associated hepatocellular carcinoma in Thailand
291
Wiechens, Nicola The chromatin remodelling ATPase SNF2H positions nucleosomes adjacent to a subset of transcription factors including CTCF
292
Wille, Alexandra Chromatin remodeling factor expression during extinction of fear 293
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EMBO Conference: Chromatin and Epigenetics
Wu, Liling Novel substrates for protein arginine methyltransferase PRMT5 294
Xu, Guoliang Tet-catalyzed DNA Oxidation in Mouse Zygotes 295
Yang, Xi Novel Post Translational Modification of UHRF1 and Its Biological Relevance
296
Yu, Seon-Mi Azacytidine (AzaC) regulates migration by inducing matrix metalloproteinase (MMP)-9 expression and COX-2 expression via PI3-kinase and ERK-1/2 pathways in HT1080 human fibrosarcoma cell line
297
Zhang, Jingchao Interactions between Otx2 and Nanog Regulate the ES Cell Self-Renewal Network
298
Zhang, Tianyi Interplay between Polycomb and Trithorax proteins 299
Zhao, Xinghui Anthrax edema toxin down regulates MIP-1a expression in macrophages by decreasing histone H3K4 trimethylation
300
Ziadlou, Reihane Epigenetic Comparison of Mesenchymal Stem Cells derived from Human Bone Marrow and Chorion
301
Ziane, Rahima Presenter: Ziane, Rahima; Radman-Livaja, Marta
Tracking maternal nucleosomes at targeted genomic loci during replication 302
Zippo, Alessio Myc-driven self-reinforcing regulatory network maintains Embryonic Stem cell identity
303
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