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Supplementary Data
A Comparison of Collision Cross Section Values Obtained via Ion Mobility Spectrometry Following Direct Infusion and an Evaluation of U(H)PLC-IM-MS for the Characterisation of Metabolites in Rat Urine
Leanne C. Nye1,2,Δ, Jonathan P. Williams1,Δ, Nyasha C. Munjoma1,2,Δ, Marine P.M. Letertre2,Δ, Muireann Coen2,3, Robbin Bouwmeester4,5, Lennart Martens4,5, Jonathan R. Swann2, Jeremy K. Nicholson6, Robert S. Plumb7, Michael McCullagh1,Δ, Lee A. Gethings1, Steven Lai8, James I. Langridge1, Johannes P.C. Vissers1,*, Ian D. Wilson2,*
1. Waters Corporation, Wilmslow, SK9 4AX, UK
2. Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK
3. Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Unit 310, Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK
4. VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium
5. Faculty of Medicine and Health Sciences, Department of Biochemistry, Ghent University, Ghent, Belgium
6. Australian National Phenome Centre, Murdoch University, Harry Perkins Building, Perth, WA
7. Waters Corporation, Milford, MA, USA
8. Waters Corporation, Beverly, MA, USA
Δ contributed equally
* to whom correspondence should be addressed:
Contents:
Figure S1.Tentative identification example of native lumichrome (6,7-dimethylalloxazine) in a study pool 3
QC rat urine sample based on MS, tr, TWCCSN2 and IM resolved CID MS2 using data independent analysis
RAMMP-U(H)PLC-IM-MS/MS.
Table S1.MSMLS library meta data. 4
Table S2a.TWCCSN2 values from direct infusion in positive-ion mode. 17
Table S2b.TWCCSN2 values from direct infusion in negative-ion mode. 31
Table S3.Non-detected metabolites in DI-IM-MS and their (neutral) molecular mass. 44
Table S4. Reference TWCCSN2 values obtained from Beverly, MA demonstration laboratory 45
Waters Corporation and Paglia et al.
Table S5. Direct infusion vs. RAMMP in positive-ion mode. 51
Table S6.Retention time values in minutes for the compounds tentatively identified as present in rat urine. 58
- 21 -
Figure S1. Tentative identification example of native lumichrome (6,7-dimethylalloxazine) in a study pool QC rat urine sample based on MS, tr, TWCCSN2 and IM resolved CID MS2 using data independent analysis RAMMP-U(H)PLC-IM-MS/MS.
Table S1. MSMLS library meta data. * = predicted TWCCSN2 values for HMDB compounds, † supplier provided, ‡ D or L.
Plate Position
Compound†
Formula†
Neutral mass†
PubChem CID†
HMDB
ID
predicted TWCCS N2 (Å2) *
[M+H]
[M+Na]
[M+K]
[M-H]
1_A1
1_A2
1_A3
1_A4
1_A5
1_A6
1_A7
1_A8
1_A9
1_A10
1_A11
1_A12
1_B1
1_B2
1_B3
1_B4
1_B5
1_B6
1_B7
1_B8
1_B9
1_B10
1_B11
1_B12
1_C1
1_C2
1_C3
1_C4
1_C5
1_C6
1_C7
1_C8
1_C9
1_C10
1_C11
1_C12
1_D1
1_D2
1_D3
1_D4
1_D5
1_D6
1_D7
1_D8
1_D9
1_D10
1_D11
1_D12
1_E1
1_E2
1_E3
1_E4
1_E5
1_E6
1_E7
1_E8
1_E9
1_E10
1_E11
1_E12
1_F1
1_F2
1_F3
1_F4
1_F5
1_F6
1_F7
1_F8
1_F9
1_F10
1_F11
1_F12
1_G1
1_G2
1_G3
1_G4
1_G5
1_G6
1_G7
1_G8
1_G9
1_G10
1_G11
1_G12
1_H1
1_H2
1_H3
1_H4
1_H5
1_H6
1_H7
1_H8
1_H9
1_H10
1_H11
1_H12
2_A1
2_A2
2_A3
2_A4
2_A5
2_A6
2_A7
2_A8
2_A9
2_A10
2_A11
2_A12
2_B1
2_B2
2_B3
2_B4
2_B5
2_B6
2_B7
2_B8
2_B9
2_B10
2_B11
2_B12
2_C1
2_C2
2_C3
2_C4
2_C5
2_C6
2_C7
2_C8
2_C9
2_C10
2_C11
2_C12
2_D1
2_D2
2_D3
2_D4
2_D5
2_D6
2_D7
2_D8
2_D9
2_D10
2_D11
2_D12
2_E1
2_E2
2_E3
2_E4
2_E5
2_E6
2_E7
2_E8
2_E9
2_E10
2_E11
2_E12
2_F1
2_F2
2_F3
2_F4
2_F5
2_F6
2_F7
2_F8
2_F9
2_F10
2_F11
2_F12
2_G1
2_G2
2_G3
2_G4
2_G5
2_G6
2_G7
2_G8
2_G9
2_G10
2_G11
2_G12
2_H1
2_H2
2_H3
2_H4
2_H5
2_H6
2_H7
2_H8
2_H9
2_H10
2_H11
2_H12
3_A1
3_A2
3_A3
3_A4
3_A5
3_A6
3_A7
3_A8
3_A9
3_A10
3_A11
3_A12
3_B1
3_B2
3_B3
3_B4
3_B5
3_B6
3_B7
3_B8
3_B9
3_B10
3_B11
3_B12
3_C1
3_C2
3_C3
3_C4
3_C5
3_C6
3_C7
3_C8
3_C9
3_C10
3_C11
3_C12
3_D1
3_D2
3_D3
3_D4
3_D5
3_D6
3_D7
3_D8
3_D9
3_D10
3_D11
3_D12
3_E1
3_E2
3_E3
3_E4
3_E5
3_E6
3_E7
3_E8
3_E9
3_E10
3_E11
3_E12
3_F1
3_F2
3_F3
3_F4
3_F5
3_F6
3_F7
3_F8
3_F9
3_F10
3_F11
3_F12
3_G1
3_G2
3_G3
3_G4
3_G5
3_G6
3_G7
3_G8
3_G9
3_G10
3_G11
3_G12
3_H1
3_H2
3_H3
3_H4
3_H5
3_H6
3_H7
3_H8
3_H9
3_H10
3_H11
3_H12
4_A1
4_A2
4_A3
4_A4
4_A5
4_A6
4_A7
4_A8
4_A9
4_A10
4_A11
4_A12
4_B1
4_B2
4_B3
4_B4
4_B5
4_B6
4_B7
4_B8
4_B9
4_B10
4_B11
4_B12
4_C1
4_C2
4_C3
4_C4
4_C5
4_C6
4_C7
4_C8
4_C9
4_C10
4_C11
4_C12
4_D1
4_D2
4_D3
4_D4
4_D5
4_D6
4_D7
4_D8
4_D9
4_D10
4_D11
4_D12
4_E1
4_E2
4_E3
4_E4
4_E5
4_E6
4_E7
4_E8
4_E9
4_E10
4_E11
4_E12
4_F1
4_F2
4_F3
4_F4
4_F5
4_F6
4_F7
4_F8
4_F9
4_F10
4_F11
4_F12
4_G1
4_G2
4_G3
4_G4
4_G5
4_G6
4_G7
4_G8
4_G9
4_G10
4_G11
4_G12
4_H1
4_H2
4_H3
5_A1
5_A2
5_A3
5_A4
5_A5
5_A6
5_A7
5_A8
5_A9
5_A10
5_A11
5_A12
5_B1
5_B2
5_B3
5_B4
5_B5
5_B6
5_B7
5_B8
5_B9
5_B10
5_B11
5_B12
5_C1
5_C2
5_C3
5_C4
5_C5
5_C6
5_C7
5_C8
5_C9
5_C10
5_C11
5_C12
5_D1
5_D2
5_D3
5_D4
5_D5
5_D6
5_D7
5_D8
5_D9
5_D10
5_D11
5_D12
5_E1
5_E2
5_E3
5_E4
5_E5
5_E6
5_E7
5_E8
5_E9
5_E10
5_E11
5_E12
5_F1
5_F2
5_F3
5_F4
5_F5
5_F6
5_F7
5_F8
5_F9
5_F10
5_F11
5_F12
5_G1
5_G2
5_G3
5_G4
5_G5
5_G6
5_G7
5_G8
5_G9
5_G10
5_G11
5_G12
5_H1
5_H2
5_H3
5_H4
5_H5
5_H6
5_H7
5_H8
5_H9
5_H10
5_H11
5_H12
6_A1
6_A2
6_A3
6_A4
6_A5
6_A6
6_A7
6_A8
6_A9
6_A10
6_A11
6_A12
6_B1
6_B2
6_B3
6_B4
6_B5
6_B6
6_B7
6_B8
6_B9
6_B10
6_B11
6_B12
6_C1
6_C2
6_C3
6_C4
6_C5
6_C6
6_C7
6_C8
6_C9
6_C10
6_C11
6_C12
6_D1
6_D2
6_D3
6_D4
6_D5
6_D6
6_D7
6_D8
6_D9
6_D10
6_D11
6_D12
6_E1
6_E2
6_E3
6_E4
6_E5
6_E6
6_E7
6_E8
6_E9
6_E10
6_E11
6_E12
6_F1
6_F2
6_F6
6_F7
6_F8
6_F9
6_F10
6_F11
6_F12
6_G1
6_G2
6_G3
6_G4
6_G5
6_G6
6_G7
6_G8
6_G9
6_G10
6_G11
6_G12
6_H1
6_H2
6_H3
6_H4
6_H5
6_H6
7_A1
7_A2
7_A3
7_A4
7_A5
7_A6
7_A7
7_A8
7_A9
7_A10
7_A11
7_A12
7_B1
7_B2
7_B3
7_B4
7_B5
7_B6
7_B7
7_B8
7_B9
7_B10
7_B11
7_B12
7_C1
7_C2
7_C3
7_C4
7_C5
7_C6
7_C7
7_C8
7_C9
7_C10
7_C11
7_C12
7_D1
7_D2
7_D3
7_D4
7_D5
7_D6
7_D7
7_D8
7_D9
7_D10
7_D11
7_D12
7_E1
7_E2
7_E3
7_E4
7_E5
7_E6
7_E7
7_E8
7_E9
7_E10
7_E11
7_E12
7_F1
7_F2
7_F3
7_F4
7_F5
7_F6
7_F7
7_F8
7_F9
7_F10
7_F11
7_F12
7_G1
7_G2
7_G3
7_G4
NAD
L-GLUTAMINE
HYPOTAURINE
INOSINE 5'-PHOSPHATE
CITRATE
L-THREONINE
PURINE
N-ACETYLNEURAMINATE
L-KYNURENINE
PYRIMIDINE
D-ASPARTATE
URATE
CYTIDINE
L-SERINE
L-CYSTEINE
CITRULLINE
TAURINE
D-GLUCONO-1,5-LACTONE
NICOTINATE
INOSINE
4-AMINOBUTANOATE
CYTOSINE
L-ISOLEUCINE
PYRAZOLE
L-GLUTAMIC ACID
ASCORBATE
BETA-ALANINE
N-ACETYL-D-GLUCOSAMINE
GLYCOLATE
SARCOSINE
GLUCONIC ACID
QUINATE
(S)-DIHYDROOROTATE
MALONATE
PIPECOLATE
FORMAMIDE
GLYCINE
L-METHIONINE
TETRAHYDROFOLATE
ADENINE
5'-METHYLTHIOADENOSINE
THYMIDINE
GLYCERATE
OROTATE
ETHANOLAMINE PHOSPHATE
XANTHINE
DIHYDROFOLATE
L-CYSTINE
L-ALANINE
L-TRYPTOPHAN
URIDINE-5-MONOPHOSPHATE
L-PROLINE
THYMINE
SUCCINATE SEMIALDEHYDE
(S)-LACTATE
URIDINE
FRUCTOSE 1,6-BIPHOSPHATE
CARNOSINE
NICOTINAMIDE
SHIKIMATE
SUCCINATE
L-PHENYLALANINE
URACIL
(S)-MALATE
L-ASPARTATE
2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE
HYPOXANTHINE
CREATINE
3,4-DIHYDROXY-L-PHENYLALANINE
GUANOSINE
5,6-DIHYDROURACIL
(R)-MALATE
L-LYSINE
L-TYROSINE
GLYCEROL
L-ASPARAGINE
L-VALINE
GUANINE
HOMOSERINE
PYRIDOXINE
DAMP
(R,R)-TARTARIC ACID
NICOTINAMIDE MONONUCLEOTIDE
FOLIC ACID
ISOCITRIC ACID
THIOUREA
DIETHANOLAMINE
3-AMINOISOBUTANOATE
CYS-GLY
L-2-PHOSPHOGLYCERIC ACID
GUANIDINOACETATE
CREATININE
N-ACETYL-D-TRYPTOPHAN‡
TRANS-ACONITATE
N-ACETYL-D-MANNOSAMINE
D-GLUCOSE-6-PHOSPHATE
LL-2,6-DIAMINOHEPTANEDIOATE
ALPHA-AMINOADIPATE
DEOXYCYTIDINE
NORADRENALINE
D-GLUCOSAMINE 6-PHOSPHATE
(S,S)-TARTARIC ACID
3-DEHYDROSHIKIMATE
BIS(3-AMINOPROPYL)AMINE
HOMOCYSTEINE
THEOPHYLLINE
LEUCINE‡
D-(+)-TREHALOSE
BETAINE
D-TRYPTOPHAN
3-SULFINO-L-ALANINE
O-SUCCINYL-L-HOMOSERINE
ALLANTOIN
GLYCERALDEHYDE
D-GLUCURONOLACTONE
(2-AMINOETHYL)PHOSPHONATE
SELENOMETHIONINE
MALEIMIDE
FORMATE
D-(+)-GLUCOSAMINE
PARAXANTHINE
ADENOSINE 5'-DIPHOSPHATE
2-DEOXY-D-GLUCOSE
N(PAI)-METHYL-L-HISTIDINE
GALACTITOL
5-OXO-D-PROLINE
4-PYRIDOXATE
PYRIDINE-2,3-DICARBOXYLATE
METHYLGUANIDINE
CAFFEINE
ACETALDEHYDE
D-GLUCURONIC ACID
1-METHYLADENOSINE
DEOXYURIDINE
TRANS-4-HYDROXYPROLINE
UROCANATE
KYNURENINE
5-OXO-L-PROLINE
4-ACETAMIDOBUTANOATE
TRANS-CYCLOHEXANE-1,2-DIOL
MELANIN
DOPAMINE
PUTRESCINE
L-LYSINE
CYTIDINE 5'-DIPHOSPHOCHOLINE
1,3-DIAMINOPROPANE
O-PHOSPHO-L-SERINE
1-AMINOCYCLOPROPANE-1-CARBOXYLATE
5-HYDROXYMETHYLURACIL
L-CYSTATHIONINE
L-NORVALINE
3-HYDROXY-3-METHYLGLUTARATE
PHOSPHONOACETATE
PICOLINIC ACID
ETHANOLAMINE
L-ARGININE
4-HYDROXY-L-PROLINE
6-DEOXY-L-GALACTOSE
HOMOCYSTINE
N-METHYL-L-GLUTAMATE
D-ORNITHINE
XANTHOSINE
3-METHYLCROTONYL-COA
THYROTROPIN RELEASING HORMONE
3'-CMP
N-METHYL-D-ASPARTIC ACID
GALACTARATE
L-HISTIDINE
NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE
N-ALPHA-ACETYL-L-ASPARAGINE
L-PIPECOLIC ACID
D-GLUCOSE 6-PHOSPHATE
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE
CARBAMOYL PHOSPHATE
ISOPENTENYL PYROPHOSPHATE
GUANOSINE 5'-TRIPHOSPHATE
THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE
AGMATINE SULFATE
GLYCOLALDEHYDE DIMER
2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE
N-ACETYLGLYCINE
N-ACETYL-L-ASPARTIC ACID
INOSINE 5'-DIPHOSPHATE
2'-DEOXYADENOSINE 5'-DIPHOSPHATE
2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE
NICOTINAMIDE HYPOXANTHINE DINUCLEOTIDE
S-(5'-ADENOSYL)-L-METHIONINE
6-PHOSPHOGLUCONIC ACID
ALPHA-HYDROXYISOBUTYRIC ACID
L-CYSTEIC ACID
ADENOSINE 5'-MONOPHOSPHATE
D-GLUCONATE
PUTRESCINE
DEOXYCARNITINE
ADENOSINE 2',3'-CYCLIC MONOPHOSPHATE
MEVALOLACTONE
URIDINE 5'-DIPHOSPHOGLUCOSE
GAMMA,GAMMA-DIMETHYLALLYL PYROPHOSPHATE
2'-DEOXYURIDINE 5'-TRIPHOSPHATE
PHOSPHOCHOLINE
URIDINE 5'-TRIPHOSPHATE
6-HYDROXYDOPAMINE
THIAMINE
2'-DEOXYGUANOSINE 5'-DIPHOSPHATE
5-METHYLCYTOSINE HYDROCLORIDE
D-GLYCERIC ACID
CYTIDINE 2',3'-CYCLIC MONO-PHOSPHATE
NEPSILON,NEPSILON,NEPSILON-TRIMETHYLLYSINE
PHOSPHO(ENOL)PYRUVIC ACID
GUANOSINE 5'-DIPHOSPHOGLUCOSE
ALPHA-D-GALACTOSE 1-PHOSPHATE
PYRIDOXAL 5'-PHOSPHATE
DIHYDROXYACETONE PHOSPHATE
PHOSPHO(ENOL)PYRUVIC ACID
D-MANNOSE 6-PHOSPHATE
D-(-)-3-PHOSPHOGLYCERIC ACID
L-CARNITINE
2-AMINOETHYL DIHYDROGEN PHOSPHATE
O-ACETYL-L-SERINE
THYMIDINE 5'-MONOPHOSPHATE
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE
ADENOSINE-5'-DIPHOSPHOGLUCOSE
D-FRUCTOSE 6-PHOSPHATE
ADENOSINE 3',5'-DIPHOSPHATE
3-NITRO-L-TYROSINE
OCTOPAMINE
NALPHA-ACETYL-L-LYSINE
URIDINE 5'-DIPHOSPHOGALACTOSE
SPERMIDINE
PYRIDOXAMINE
5-AMINOLEVULINIC ACID
2'-DEOXYURIDINE 5'-MONO-PHOS-PHATE
ADENOSINE 5'-TRIPHOSPHATE
D-RIBULOSE 1,5-BISPHOSPHATE
XANTHOSINE 5'-MONOPHOSPHATE
FLAVIN ADENINE DINUCLEOTIDE
2'-DEOXYGUANOSINE
OROTIC ACID
LAUROYLCARNITINE
1-METHYLNICOTINAMIDE
SPERMINE
N-ACETYL-DL-METHIONINE
CARBAMOYLPHOSPHATE
5-PHOSPHO-D-RIBOSE 1-DIPHOSPHATE
4-CARBOXY-5-AMINOIMIDAZOLE RIBOTIDE
URIDINE 5'-DIPHOSPHO-N-ACETYLGALACTOSAMINE
GLYCERALDEHYDE 3-PHOSPHATE DIETHYL ACETAL
GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE
L-HOMOCYSTEINE THIOLACTONE
O-PHOSPHO-DL-SERINE
S-(5'-ADENOSYL)-L-HOMOCYSTEINE
L-ORNITHINE
ADENINE
DL-NORMETANEPHRINE
URIDINE 5'-DIPHOSPHO-N-ACETYLGLUCOSAMINE
GUANOSINE 5'-DIPHOSPHATE
PHOSPHOCREATINE
URIDINE 5'-DIPHOSPHOGLUCURONIC ACID
2,3-DIPHOSPHO-D-GLYCERIC ACID
CYTIDINE 5'-DIPHOSPHATE
SELENOCYSTAMINE
HISTAMINE
INDOXYL SULFATE
ETHYL 3-UREIDOPROPIONATE
DEOXYRIBOSE
PHYTIC ACID
THIAMINE MONOPHOSPHATE
2,4-DIHYDROXYPYRIMIDINE-5-CARBOXYLIC ACID
S-HEXYL-GLUTATHIONE
GLYOXYLIC ACID
GUANOSINE 5'-MONOPHOSPHATE
N-ACETYL-L-ALANINE
4-GUANIDINOBUTANOATE
HYDROXYPYRUVATE
D-MANNOSAMINE
CYTOCHROME C
O-ACETYL-L-CARNITINE‡
RIBOFLAVIN
METHYL BETA-D-GALACTOSIDE
GLUTARIC ACID
DIHYDROXYFUMARIC ACID
CMP
GUANOSINE 5'-DIPHOSPHO-D-MANNOSE
5'-DEOXYADENOSINE
GLUTATHIONE
ERYTHRITOL
GLUCOSAMINATE
URIDINE 5'-TRIPHOSPHATE
2'-DEOXYADENOSINE
N-ACETYLPUTRESCINE
N-ACETYL-D-GALACTOSAMINE
N-ACETYL-DL-GLUTAMIC ACID
2,4-DIHYDROXYPTERIDINE
6-HYDROXYNICOTINATE
N-ACETYL-L-CYSTEINE
INOSINE 5'-MONOPHOSPHATE
D-PANTOTHENIC ACID
2-AMINO-2-METHYLPROPANOATE
ANILINE-2-SULFONIC ACID
S-CARBOXYMETHYL-L-CYSTEINE
L-RHAMNOSE
THIAMINE PYROPHOSPHATE
L-HISTIDINOL
THYMIDINE 5'-MONOPHOSPHATE
3-UREIDOPROPIONATE
5-AMINOPENTANOATE
NORLEUCINE
N-FORMYLGLYCINE
ADENOSINE
D-(+)-RAFFINOSE
MESO-TARTARIC ACID
2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSYLAMINE
D-SACCHARIC ACID
ADENOSINE 5'-TRIPHOSPHATE
3-METHOXY-L-TYROSINE
D-LACTOSE‡
3-HYDROXYBUTANOIC ACID
4-IMIDAZOLEACETIC ACID
D-(+)-GALACTURONIC ACID
CYTIDINE 5'-TRIPHOSPHATE
3',5'-CYCLIC AMP
L-METHIONINE SULFOXIMINE‡
CIS-4-HYDROXY-D-PROLINE
N1-ACETYLSPERMINE
MESOXALATE
NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED
3-METHYLHISTAMINE
MALEAMATE
CHOLINE
4-AMINOBUTANOATE
FORMYL-L-METHIONYL PEPTIDE
ACETYLCHOLINE
OXALIC ACID
5-HYDROXY-L-TRYPTOPHAN
D-ALANINE
THEOBROMINE
N-AMIDINO-L-ASPARTATE
L-HISTIDINE
L-ALLOTHREONINE
CREATINE PHOSPHATE
SPERMIDINE
ADENOSINE 5'-DIPHOSPHORIBOSE
2-METHOXYETHANOL
CITRAMALATE
L-ANSERINE
BILIVERDIN
DL-5-HYDROXYLYSINE‡
CYSTEAMINE
OPHTHALMIC ACID
L-2,3-DIAMINOPROPIONIC ACID
TRIGONELLINE
EPINEPHRINE
3,4-DIHYDROXYPHENYL GLYCOL
CADAVERINE
2-HYDROXYBUTYRIC ACID
COENZYME A
OXALOMALIC ACID
INOSINE 5'-TRIPHOSPHATE
SN-GLYCERO-3-PHOSPHOCHOLINE
2,5-DIMETHYLPYRAZINE
STACHYOSE
2'-DEOXYCYTIDINE 5'-DIPHOSPHATE
(2R,3R)-(-)-2,3-BUTANEDIOL
D-RIBOSE 5-PHOSPHATE
3-HYDROXYKYNURENINE
D-(+)-GALACTOSAMINE
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
SN-GLYCEROL 3-PHOSPHATE
VITAMIN B12
4-HYDROXY-L-PHENYLGLYCINE
N-ACETYL-DL-SERINE
URIDINE 5'-DIPHOSPHATE
GLYCEROL 2-PHOSPHATE
ALPHA-D-GLUCOSE 1-PHOSPHATE
D-GLUCOSAMINE 6-SULFATE
3-METHYGLUTARIC ACID
SORBATE
MONO-ETHYL MALONATE
DIMETHYL SULFIDE
4-HYDROXYBENZOATE
TYRAMINE
CORTISOL
PRENOL
3-HYDROXYBENZALDEHYDE
XANTHURENIC ACID
2-METHYLPROPANAL OXIME
PROPIONATE
TRIMETHYLAMINE
MELATONIN
MALEIC ACID
PENTANOATE
PROPANOATE
BILIRUBIN
(S)-NICOTINE
BUTANAL
4-HYDROXY-2-QUINOLINECARBOXYLIC ACID
2-METHYLPROPANOATE
3-HYDROXYBENZYL ALCOHOL
ANILINE
4-HYDROXYPHENYLACETATE
3,5-DIIODO-L-TYROSINE
MANDELIC ACID
TRYPTAMINE
BENZOATE
GLUTARATE
INDOLE-3-ACETATE
CAFFEATE
LUMICHROME
6-CARBOXYHEXANOATE
N-ACETYL-L-PHENYLALANINE
AMYLOSE
L-TRYPTOPHANAMIDE
PHENOL
N-?-METHYLTRYPTAMINE
OXALOACETATE
2,3-DIHYDROXYBENZOATE
PROPENOATE
INDOLE-3-ETHANOL
FERULATE
GLYCOCHOLATE
PHENYLETHANOLAMINE
THIOPURINE S-METHYLETHER
2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID
PROPANAL
BENZOATE
3-AMINO-5-HYDROXYBENZOIC ACID
CATECHOL
3,4-DIHYDROXYBENZOATE
CYCLOPENTANONE
PANTOLACTONE
GUAIACOL
2-HYDROXYPHENYLACETIC ACID
10-HYDROXYDECANOATE
1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2-HYDROXYPYRIDINE
3,4-DIHYDROXYPHENYLACETATE
N6-(DELTA2-ISOPENTENYL)-ADENINE
METHYL VANILLATE
2-OXOBUTANOATE
LIPOAMIDE
3-HYDROXYANTHRANILATE
3-(4-HYDROXYPHENYL)PYRUVATE
HEXANOATE
METHYLMALONATE
SEROTONIN CREATININE SULFATE COMPLEX
CORTISOL 21-ACETATE
INDOLE-3-ACETAMIDE
HIPPURATE
ETHYLMALONIC ACID
3,5-DIIODO-L-THYRONINE
FUMARATE
BENZALDEHYDE
4-HYDROXYBENZALDEHYDE
3-(2-HYDROXYPHENYL)PROPANOATE
3-METHOXYTYRAMINE
BENZYLAMINE
2-QUINOLINECARBOXYLIC ACID
SEROTONIN
PTERIN
4-AMINOBENZOATE
2-AMINOPHENOL
ACETOIN
INDOLE-3-PYRUVIC ACID
DEHYDRO-L-(+)-ASCORBIC ACID DIMER
3-AMINO-4-HYDROXYBENZOIC ACID
DIHYDROXYMANDELIC ACID
ANTHRANILATE
THIOACETATE
BUTANOATE
INDOLE-3-ACETIC ACID
5-VALEROLACTONE
2,5-DIHYDROXYBENZOATE
2-METHYLMALEATE
HYDROQUINONE
DETHIOBIOTIN
3-METHYL-2-OXOVALERIC ACID
ALPHA-KETOGLUTARIC ACID
N-ACETYLSEROTONIN
3-METHYLBUTANAL
ITACONATE
AZELAIC ACID
MONO-METHYL GLUTARATE
2-METHYLGLUTARIC ACID
PHENYLACETALDEHYDE
2-METHYLBUTANAL
PHENYL ACETATE
DIACETYL
PYRUVATE
TRANS-CINNAMALDEHYDE
2,6-DIHYDROXYPYRIDINE
PHENETHYLAMINE
METHYL ACETOACETATE
SUBERIC ACID
ADIPIC ACID
GERANYL PYROPHOSPHATE
N-ACETYL-L-LEUCINE
2',4'-DIHYDROXYACETOPHENONE
BENZYL ALCOHOL
2-OXOADIPATE
METHYL INDOLE-3-ACETATE
PROPYNOATE
3-METHOXY-4-HYDROXYMANDELATE
HOMOVANILLATE
4-QUINOLINECARBOXYLIC ACID
(S)-1-PHENYLETHANOL
1-METHYL-6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE
SALICYLAMIDE
3-HYDROXYBENZOATE
4-METHYL-2-OXOVALERIC ACID
2'-DEOXYURIDINE 5'-MONO-PHOS-PHATE
N,N-DIMETHYL-1,4-PHENYLENEDIAMINE
HOMOGENTISATE
INDOLE-3-ACETALDEHYDE
4-HYDROXY-3-METHOXYPHENYLGLYCOL
3-HYDROXYPHENYLACETATE
4-METHYLCATECHOL
PYRIDOXAL
SALICYLATE
3-METHYLBUTANOL
3-METHYL-2-OXINDOLE
3-METHYLADENINE
3-(4-HYDROXYPHENYL)LACTATE
BIOTIN
MERCAPTOPYRUVATE
PYRUVIC ALDEHYDE
PYRROLE-2-CARBOXYLATE
5-HYDROXYINDOLEACETATE
PHENYLACETIC ACID
RESORCINOL MONOACETATE
ACETOACETATE
ACETYL PHOSPHATE
ETHYL 3-INDOLEACETATE
DEHYDROASCORBATE
D-FRUCTOSE
L-SORBOSE
XYLITOL
RIBITOL
MYO-INOSITOL
MANNOSE
ARABINOSE
D-XYLOSE
SUCROSE
D-GALACTOSE
ALPHA-D-GLUCOSE
ALLOSE
MANNITOL
MELIBIOSE
D-SORBITOL
MALTOSE
D-TAGATOSE
D-GULONIC ACID GAMA-LACTONE
D-(-)-ARABINOSE
D-(+)-CELLOBIOSE
D-PSICOSE
L-ARABITOL
D-LYXOSE
D-RIBOSE
PALATINOSE
VITAMIN D2
SQUALENE
4-COUMARATE
NONANOATE
CHENODEOXYCHOLATE
CAPRYLIC ACID
CHOLESTERYL ACETATE
PETROSELINIC ACID
1,2-DIPALMITOYL-SN-GLYCEROL
3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLANATE
3ALPHA-HYDROXY-5BETA-CHOLANATE
PROTOPORPHYRIN
HEPTANOIC ACID
RETINOL
MENAQUINONE
ELAIDIC ACID
ESTRADIOL-17ALPHA
MYRISTIC ACID
CHOLESTERYL OLEATE
ROSMARINIC ACID
GLYCERYL TRIPALMITATE
6.11-DEOXY-CORTISOL
TAUROLITHOCHOLATE
PALMITOLEIC ACID
PALMITATE
3,3',5'-TRIIODOTHYRONINE
SPHINGANINE
LANOSTEROL
LAURIC ACID
ARACHIDIC ACID
ERUCIC ACID
DEOXYCHOLATE
4-METHYL-2-OXO-PENTANOIC ACID
LEUKOTRIENE B4
HEPTADECANOATE
GLYCERYL TRIMYRISTATE
LINOLEATE
SPHINGOMYELIN
CHOLESTA-5,7-DIEN-3BETA-OL
THYROXINE
BIS(2-ETHYLHEXYL)PHTHALATE
GAMMA-LINOLENIC ACID
OMEGA-HYDROXYDODECANOIC ACID
METHYL JASMONATE
GERANYLGERANYL PYROPHOSPHATE
HEXADECANOL
DIMETHYLBENZIMIDAZOLE
RETINOATE
INDOLE
CHOLATE
PHYLLOQUINONE
CHOLESTERYL PALMITATE
QUINOLINE
DOCOSAHEXAENOIC ACID
DIETHYL 2-METHYL-3-OXOSUCCINATE
RETINYL PALMITATE
1-NAPHTHYLAMINE
1-HYDROXY-2-NAPHTHOATE
1,2-DIPALMITOYL-RAC-GLYCERO-3-PHOSPHOETHANOLAMINE
PHENYLPYRUVATE
TRANS-CINNAMATE
OLEATE
STEARATE
BETA-CAROTENE
25-HYDROXYCHOLESTEROL
NERVONIC ACID
DESMOSTEROL
DEOXYCORTICOSTERONE ACETATE
1-OLEOYL-RAC-GLYCEROL
ALPHA-TOCOPHEROL
RAC-GLYCEROL 1-MYRISTATE
TRICOSANOIC ACID
FARNESYL DIPHOSPHATE
CORTISONE
DECANOATE
CORTICOSTERONE
C21H27N7O14P2
C5H10N2O3
C2H7NO2S
C10H13N4O8P
C6H8O7
C4H9NO3
C5H4N4
C11H19NO9
C10H12N2O3
C4H4N2
C4H7NO4
C5H4N4O3
C9H13N3O5
C3H7NO3
C3H7NO2S
C6H13N3O3
C2H7NO3S
C6H12O7
C6H5NO2
C10H12N4O5
C4H9NO2
C4H5N3O
C6H13NO2
C3H3N2
C5H9NO4
C6H8O6
C3H7NO2
C8H15NO6
C2H4O3
C3H7NO2
C6H12O7
C7H12O6
C5H6N2O4
C3H4O4
C6H11NO2
CH3NO
C2H5NO2
C5H11NO2S
C19H23N7O6
C5H5N5
C11H15N5O3S
C10H14N2O5
C3H6O4
C5H4N2O4
C2H8NO4P
C5H4N4O2
C19H21N7O6
C6H12N2O4S2
C3H7NO2
C11H12N2O2
C9H13N2O9P
C5H9NO2
C5H6N2O2
C4H6O3
C3H6O3
C9H12N2O6
C6H14O12P2
C9H14N4O3
C6H6N2O
C7H10O5
C4H6O4
C9H11NO2
C4H4N2O2
C4H6O5
C4H7NO4
C9H14N3O7P
C5H4N4O
C4H9N3O2
C9H11NO4
C10H13N5O5
C4H6N2O2
C4H6O5
C6H14N2O2
C9H11NO3
C3H8O3
C4H8N2O3
C5H11NO2
C5H5N5O
C4H9NO3
C8H11NO3
C10H14N5O6P
C4H6O6
C11H15N2O8P
C19H19N7O6
C6H8O7
CH4N2S
C4H11NO2
C4H9NO2
C5H10N2O3S
C3H7O7P
C3H7N3O2
C4H7N3O
C13H14N2O3
C6H6O6
C8H15NO6
C6H13O9P
C7H14N2O4
C6H11NO4
C9H13N3O4
C8H11NO3
C6H14NO8P
C4H6O6
C7H8O5
C6H17N3
C4H9NO2S
C7H8N4O2
C6H13NO2
C12H22O11
C5H11NO2
C11H12N2O2
C3H7NO4S
C8H13NO6
C4H6N4O3
C3H6O3
C6H10O7
C2H8NO3P
C5H11NO2Se
C4H3NO2
CH2O2
C6H13NO5
C7H8N4O2
C10H15N5O10P2
C6H12O5
C7H11N3O2
C6H14O6
C5H7NO3
C8H9NO4
C7H5NO4
C2H7N3
C8H10N4O2
C2H4O
C6H10O7
C11H15N5O4
C9H12N2O5
C5H9NO3
C6H6N2O2
C10H12N2O3
C5H7NO3
C6H11NO3
C6H12O2
C18H10N2O4
C8H11NO2
C4H12N2
C6H14N2O2
C14H26N4O11P2
C3H10N2
C3H8NO6P
C4H7NO2
C5H6N2O3
C7H14N2O4S
C5H11NO2
C6H10O5
C2H5O5P
C6H5NO2
C2H7NO
C6H14N4O2
C5H9NO3
C6H12O5
C8H16N2O4S2
C6H11NO4
C5H12N2O2
C10H12N4O6
C26H42N7O17P3S
C16H22N6O4
C9H14N3O8P
C5H9NO4
C6H10O8
C6H9N3O2
C21H27N6O18P3
C6H10N2O4
C6H11NO2
C6H13O9P
C21H28N7O17P3
CH4NO5P
C5H12O7P2
C10H16N5O14P3
C16H26N2O16P2
C5H14N4
C2H4O2
C10H16N5O13P3
C4H7NO3
C6H9NO5
C10H14N4O11P2
C10H15N5O9P2
C10H14N5O7P
C21H26N6O15P2
C15H22N6O5S
C6H13O10P
C4H8O3
C3H7NO5S
C10H14N5O7P
C6H12O7
C4H12N2
C7H15NO2
C10H12N5O6P
C6H12O4
C15H24N2O17P2
C5H12O7P2
C9H15N2O14P3
C5H14NO4P
C9H15N2O15P3
C8H11NO3
C12H17N4OS
C10H15N5O10P2
C5H7N3O
C3H6O4
C9H12N3O7P
C9H20N2O2
C3H5O6P
C16H25N5O16P2
C6H13O9P
C8H10NO6P
C3H7O6P
C3H5O6P
C6H13O9P
C3H7O7P
C7H15NO3
C2H8NO4P
C5H9NO4
C10H15N2O8P
C10H12N5O6P
C16H25N5O15P2
C6H13O9P
C10H15N5O10P2
C9H10N2O5
C8H11NO2
C8H16N2O3
C15H24N2O17P2
C7H19N3
C8H12N2O2
C5H9NO3
C9H13N2O8P
C10H16N5O13P3
C5H12O11P2
C10H13N4O9P
C27H33N9O15P2
C10H13N5O4
C5H4N2O4
C19H37NO4
C7H9N2O
C10H26N4
C7H13NO3S
CH4NO5P
C5H13O14P3
C9H15N4O8P
C17H27N3O17P2
C7H15BaO7P
C10H12N5O7P
C4H7NOS
C3H8NO6P
C14H20N6O5S
C5H12N2O2
C5H5N5
C9H13NO3
C17H27N3O17P2
C10H15N5O11P2
C4H10N3O5P
C15H22N2O18P2
C3H8O10P2
C9H15N3O11P2
C4H12N2Se2
C5H9N3
C8H7NO4S
C6H12N2O3
C5H10O4
C6H18O24P6
C12H17N4O4PS
C5H4N2O4
C16H29N3O6S
C2H2O3
C10H14N5O8P
C5H9NO3
C5H11N3O2
C3H4O4
C6H13NO5
C42H52FeN8O6S2
C9H17NO4
C17H20N4O6
C7H14O6
C5H8O4
C4H4O6
C9H14N3O8P
C16H25N5O16P2
C10H13N5O3
C10H17N3O6S
C4H10O4
C6H13NO6
C9H15N2O15P3
C10H13N5O3
C6H14N2O
C8H15NO6
C7H11NO5
C6H4N4O2
C6H5NO3
C5H9NO3S
C10H13N4O8P
C9H17NO5
C4H9NO2
C6H7N
C5H9NO4S
C6H12O5
C12H18N4O7P2S
C6H11N3O
C10H15N2O8P
C4H8N2O3
C5H11NO2
C6H13NO2
C3H5NO3
C10H13N5O4
C18H32O16
C4H6O6
C8H16N2O5
C6H10O8
C10H16N5O13P3
C10H13NO4
C12H22O11
C4H8O3
C5H6N2O2
C6H10O7
C9H16N3O14P3
C10H12N5O6P
C5H12N2O3S
C5H9NO3
C12H28N4O
C3H2O5
C21H28N7O17P3
C6H11N3
C4H5NO3
C5H14NO
C4H9NO2
C6H11NO3S
C7H16NO2
C2H2O4
C11H12N2O3
C3H7NO2
C7H8N4O2
C5H9N3O4
C6H9N3O2
C4H9NO3
C4H10N3O5P
C7H19N3
C15H23N5O14P2
C3H8O2
C5H8O5
C10H16N4O3
C33H34N4O6
C6H14N2O3
C2H7NS
C11H19N3O6
C3H8N2O2
C7H7NO2
C9H13NO3
C8H10O4
C5H14N2
C4H8O3
C21H36N7O16P3S
C6H6O8
C10H15N4O14P3
C8H20NO6P
C6H8N2
C24H42O21
C9H15N3O10P2
C4H10O2
C5H11O8P
C10H12N2O4
C6H13NO5
C10H16N5O12P3
C3H9O6P
C63H88CoN14O14P
C8H9NO3
C5H9NO4
C9H14N2O12P2
C3H9O6P
C6H13O9P
C6H13NO8S
C6H10O4
C6H8O2
C3H4O4
C2H6S
C7H6O3
C8H11NO
C21H30O5
C5H10O
C7H6O2
C10H7NO4
C4H9NO
C3H6O2
C3H9N
C13H16N2O2
C4H4O4
C5H10O2
C3H6O2
C33H36N4O6
C10H14N2
C4H8O
C10H7NO3
C4H8O2
C7H8O2
C6H7N
C8H8O3
C9H9I2NO3
C8H8O3
C10H12N2
C7H6O2
C5H8O4
C10H9NO2
C9H8O4
C12H10N4O2
C7H12O4
C11H13NO3
C14H26O11
C11H13N3O
C6H6O
C11H14N2
C4H4O5
C7H6O4
C3H4O2
C10H11NO
C10H10O4
C26H43NO6
C8H11NO
C6H6N4S
C5H10O3S
C3H6O
C7H5NaO2
C7H7NO3
C6H6O2
C7H6O4
C5H8O
C6H10O3
C7H8O2
C8H8O3
C10H20O3
C28H56NO8P
C5H5NO
C8H8O4
C10H13N5
C8H8O4
C4H6O3
C8H15NOS2
C7H7NO3
C9H8O4
C6H12O2
C4H6O4
C14H23N5O7S
C23H32O6
C10H10N2O
C9H9NO3
C5H8O4
C15H13I2NO4
C4H4O4
C7H6O
C7H6O2
C9H10O3
C9H13NO2
C7H9N
C10H7NO2
C10H12N2O
C6H5N5O
C7H7NO2
C6H7NO
C4H8O2
C11H9NO3
C6H6O6
C7H7NO3
C8H8O5
C7H7NO2
C2H4OS
C4H8O2
C10H9NO2
C5H8O2
C7H6O4
C5H6O4
C6H6O2
C10H18N2O3
C6H10O3
C5H6O5
C12H14N2O2
C5H10O
C5H6O4
C9H16O4
C6H10O4
C6H10O4
C8H8O
C5H10O
C8H8O2
C4H6O2
C3H4O3
C9H8O
C5H5NO2
C8H11N
C5H8O3
C8H14O4
C6H10O4
C10H20O7P2
C8H15NO3
C8H8O3
C7H8O
C6H8O5
C11H11NO2
C3H2O2
C9H10O5
C9H10O4
C10H7NO2
C8H10O
C10H13NO2
C7H7NO2
C7H6O3
C6H10O3
C21H34O5
C8H12N2
C8H8O4
C10H9NO
C9H12O4
C8H8O3
C7H8O2
C8H9NO3
C7H6O3
C5H12O
C9H9NO
C6H7N5
C9H10O4
C10H16N2O3S
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HMDB03331
HMDB00012
HMDB00725
HMDB00301
HMDB00684
HMDB00267
HMDB03681
--
HMDB04068
HMDB00073
HMDB01414
HMDB00182
HMDB01413
HMDB00002
HMDB00272
HMDB36458
HMDB00469
HMDB00099
--
HMDB00355
HMDB04110
HMDB02243
HMDB00149
HMDB00517
HMDB06055
HMDB00174
HMDB00575
HMDB62660
HMDB03374
HMDB00299
HMDB01493
HMDB05763
HMDB00095
HMDB02393
HMDB00639
HMDB00177
HMDB01179
HMDB06028
HMDB00716
HMDB01401
HMDB00217
HMDB01096
HMDB01347
HMDB01273
HMDB01328
HMDB01432
HMDB03344
HMDB01440
HMDB00532
HMDB00812
HMDB03335
HMDB01508
HMDB01044
--
HMDB01185
HMDB01316
HMDB00729
HMDB02757
HMDB00045
HMDB00625
HMDB01414
HMDB06831
HMDB11616
HMDB06024
HMDB00286
HMDB01347
HMDB01191
HMDB01565
HMDB00285
HMDB01537
HMDB00235
HMDB00960
HMDB02894
HMDB00139
HMDB11691
HMDB01325
HMDB00263
--
HMDB00645
HMDB01491
HMDB01473
HMDB00263
HMDB01078
HMDB00807
HMDB00062
HMDB00224
HMDB03011
HMDB01227
HMDB00058
HMDB06557
HMDB00124
HMDB00061
HMDB01904
HMDB04825
HMDB00446
HMDB00302
HMDB01257
HMDB01431
HMDB01149
HMDB01409
HMDB00538
HMDB11688
HMDB01554
HMDB01248
HMDB00085
HMDB00226
HMDB02250
HMDB00699
HMDB01256
HMDB11745
HMDB01096
HMDB00280
HMDB01517
HMDB00304
--
HMDB01314
HMDB02287
HMDB01721
HMDB00939
HMDB00214
HMDB00034
HMDB00819
HMDB00290
HMDB01201
HMDB01511
HMDB00935
HMDB01294
HMDB01546
--
HMDB00870
HMDB00682
--
HMDB03224
HMDB03502
HMDB02666
--
--
HMDB00119
HMDB01397
HMDB00766
HMDB03464
HMDB01352
--
HMDB12920
HMDB00201
HMDB00244
HMDB29965
HMDB00661
HMDB02050
HMDB00095
HMDB01163
HMDB01983
HMDB00125
HMDB02994
--
HMDB00285
HMDB00101
HMDB02064
HMDB00212
HMDB01138
--
HMDB02658
HMDB01890
HMDB00175
HMDB00210
HMDB01906
--
HMDB29415
HMDB00849
HMDB01372
HMDB03431
HMDB01227
HMDB00026
HMDB03355
HMDB01645
--
HMDB00050
HMDB03213
--
HMDB01104
HMDB00663
HMDB00538
HMDB60747
HMDB00186
HMDB00011
HMDB02024
HMDB03402
HMDB00082
HMDB00058
HMDB29430
HMDB60460
HMDB01186
HMDB31522
HMDB00217
HMDB01861
--
HMDB00097
HMDB00112
HMDB01015
HMDB00895
HMDB02329
HMDB00472
HMDB01310
HMDB02825
HMDB03157
HMDB00177
HMDB04041
HMDB01511
HMDB01257
HMDB01178
--
HMDB00426
HMDB00194
HMDB01008
HMDB00450
HMDB02991
HMDB05765
HMDB02006
HMDB00875
HMDB00068
HMDB00318
HMDB02322
HMDB00008
HMDB01423
--
HMDB00189
HMDB00086
HMDB35289
HMDB03553
HMDB01245
HMDB33007
HMDB01548
HMDB00732
--
HMDB01532
HMDB00126
HMDB00607
--
--
HMDB00295
HMDB02520
HMDB01586
HMDB00592
HMDB00752
--
HMDB00576
HMDB02303
HMDB00500
HMDB00306
HMDB00063
HMDB30124
--
HMDB00881
--
HMDB00237
HMDB00906
HMDB01389
HMDB00176
HMDB00892
HMDB00237
HMDB00054
HMDB01934
HMDB03543
HMDB00715
HMDB01873
HMDB59712
HMDB03012
HMDB00020
HMDB03474
HMDB00703
HMDB00303
HMDB01870
HMDB00661
HMDB00197
HMDB01964
--
HMDB00857
HMDB00512
HMDB03403
HMDB13318
HMDB00228
HMDB04370
HMDB00223
HMDB00397
HMDB31647
HMDB03447
HMDB00954
HMDB00138
HMDB01065
HMDB60412
HMDB37115
HMDB03366
HMDB01870
--
HMDB00957
HMDB01856
HMDB31407
--
HMDB01398
HMDB00669
--
--
HMDB13751
HMDB01336
--
HMDB00484
HMDB00005
HMDB00962
HMDB01476
HMDB00707
HMDB00535
HMDB00202
--
--
HMDB29739
HMDB00714
HMDB00622
HMDB00582
HMDB00134
HMDB06115
HMDB11718
HMDB33752
HMDB00022
HMDB33871
HMDB00842
HMDB00259
HMDB00802
HMDB01392
--
HMDB03243
HMDB60484
--
--
HMDB01866
HMDB01123
HMDB31188
HMDB00039
HMDB00197
--
HMDB00152
HMDB00634
HMDB02434
HMDB03581
HMDB00491
HMDB00208
HMDB01238
HMDB06478
HMDB02092
HMDB00784
HMDB00858
HMDB00422
HMDB06236
HMDB31526
HMDB40733
HMDB03407
HMDB00243
HMDB03441
--
HMDB12275
HMDB00310
HMDB00893
HMDB00448
HMDB01285
HMDB11756
HMDB29659
HMDB03119
HMDB00225
HMDB29738
HMDB06804
HMDB00291
HMDB00118
--
--
HMDB05199
HMDB15687
HMDB02466
HMDB00695
HMDB00526
--
HMDB00130
HMDB01190
HMDB01490
HMDB00440
HMDB00873
HMDB01545
HMDB01895
HMDB06007
--
HMDB11600
HMDB00755
HMDB00030
HMDB01368
HMDB01167
HMDB04230
HMDB00763
HMDB00209
--
HMDB00060
HMDB01494
--
HMDB01264
HMDB00660
HMDB01266
HMDB02917
HMDB00508
HMDB00211
HMDB00169
HMDB00646
HMDB00098
HMDB00258
HMDB00143
HMDB03345
HMDB01151
HMDB00765
HMDB00048
HMDB00247
HMDB00163
HMDB03418
HMDB03290
HMDB29942
HMDB00055
--
HMDB01851
--
HMDB00283
HMDB02923
HMDB00900
HMDB00256
HMDB02035
HMDB00847
HMDB00518
HMDB00482
HMDB03822
HMDB02080
HMDB07098
HMDB00626
HMDB00761
HMDB00241
HMDB00666
HMDB00305
--
HMDB00573
HMDB00429
HMDB00806
HMDB00918
HMDB03572
HMDB05356
HMDB00015
HMDB00722
HMDB03229
HMDB00220
HMDB00265
HMDB00269
HMDB01251
HMDB00638
HMDB02212
HMDB02068
HMDB00626
HMDB00695
HMDB01085
HMDB02259
HMDB42061
HMDB00673
HMDB01348
HMDB00032
HMDB00248
--
HMDB03073
HMDB02059
HMDB36583
HMDB04486
HMDB03424
HMDB03701
HMDB01852
HMDB00738
HMDB00619
HMDB03555
HMDB00885
HMDB33731
HMDB02183
HMDB32306
HMDB03648
--
--
HMDB08923
HMDB00205
HMDB00930
HMDB00207
HMDB00827
HMDB00561
HMDB06247
HMDB02368
HMDB02719
--
--
HMDB01893
--
HMDB01160
HMDB00961
HMDB02802
HMDB00511
HMDB01547
228.5
125.6
123.0
168.9
132.1
122.0
118.6
162.3
146.4
104.1
122.8
127.5
149.1
128.7
116.5
133.3
123.1
133.2
121.0
155.7
120.2
117.6
129.0
--
125.3
130.9
129.2
146.2
119.1
127.4
133.0
136.8
128.0
125.2
125.9
105.9
119.4
130.8
192.1
121.7
166.0
151.4
117.9
124.9
124.0
124.2
194.2
144.6
115.1
143.3
163.8
122.6
120.6
128.3
122.9
149.8
158.4
149.4
121.4
135.6
123.5
135.3
116.8
121.6
122.8
158.6
120.8
121.6
142.5
160.3
121.0
121.6
131.7
140.2
116.0
122.0
124.2
124.8
121.6
132.0
166.3
139.6
166.1
194.8
132.3
119.7
120.7
118.4
136.1
131.1
122.8
119.8
153.5
129.4
146.2
148.9
139.6
130.0
146.6
133.9
150.2
128.1
--
127.7
125.0
132.4
131.2
169.1
122.8
143.3
126.9
--
127.5
123.0
129.1
123.1
132.1
--
107.8
134.6
132.3
183.7
131.1
133.2
132.7
123.9
133.8
128.9
112.3
137.1
107.3
131.3
159.1
147.3
124.1
125.5
146.4
123.9
128.0
--
172.3
131.8
121.2
131.7
197.8
121.1
133.8
120.9
124.6
144.3
--
129.3
123.1
120.3
119.5
134.3
138.1
139.4
152.6
130.3
128.6
158.3
259.9
156.2
164.2
125.8
137.0
128.4
228.8
133.0
125.9
148.9
233.4
127.4
144.4
197.2
208.7
127.3
119.1
191.1
122.1
132.3
180.7
181.5
165.6
--
184.6
147.9
119.9
130.7
169.5
133.0
121.2
132.4
169.0
124.4
207.2
144.4
183.0
135.1
184.5
133.0
159.4
183.1
120.6
117.9
159.8
146.4
130.8
--
149.0
149.2
143.0
130.8
148.9
131.7
132.9
124.0
125.9
165.4
170.3
196.8
147.2
183.3
149.9
131.0
143.3
207.2
132.3
133.8
124.8
159.5
195.5
153.3
170.6
246.6
153.3
124.9
202.5
125.7
149.5
141.4
127.4
165.8
167.6
216.9
--
169.6
123.5
133.8
180.9
128.6
121.7
141.0
216.9
185.7
141.7
210.2
139.6
175.0
--
121.0
126.2
--
126.6
206.8
172.9
--
--
119.6
174.4
124.8
127.5
130.6
--
118.1
143.2
185.8
138.5
122.8
133.9
164.2
206.6
154.5
167.2
122.3
--
184.5
155.7
129.2
146.2
135.4
--
123.3
131.8
168.9
145.1
120.9
--
133.1
139.4
186.1
127.5
165.4
124.5
123.3
131.1
--
156.1
205.5
--
146.9
137.0
195.5
147.8
169.2
127.0
124.8
131.3
185.0
170.3
134.6
124.1
158.5
128.2
233.4
123.8
--
118.1
120.2
136.3
132.8
122.2
148.1
115.1
131.4
133.1
128.4
122.0
141.7
132.3
211.1
--
125.2
152.7
242.2
133.3
128.0
162.1
120.5
123.2
140.2
133.2
123.4
120.5
243.3
--
191.6
151.8
118.9
232.1
171.4
122.3
140.7
148.4
--
191.5
131.2
340.8
--
--
174.9
131.2
149.0
150.4
127.3
--
122.6
110.4
125.1
129.4
188.2
118.9
--
136.5
--
116.5
119.4
152.5
120.6
122.1
116.5
245.3
135.5
119.3
134.3
124.4
122.0
117.0
126.7
159.7
127.3
137.0
121.3
122.8
132.9
135.0
--
131.3
144.8
131.3
142.7
115.3
136.4
123.5
124.8
116.6
132.9
139.8
204.0
128.5
128.0
129.0
117.4
121.3
--
118.4
126.4
117.5
--
120.2
126.2
--
--
116.3
132.1
--
134.5
133.3
143.1
131.1
133.6
124.1
125.9
--
--
134.6
137.1
123.1
191.3
120.6
116.6
121.1
131.4
137.4
119.0
131.5
136.4
127.3
129.7
--
125.8
141.4
--
--
135.5
130.3
121.5
124.7
132.9
--
125.8
122.6
120.3
149.1
124.6
129.1
147.2
119.3
121.8
140.2
126.8
127.6
120.7
119.4
125.9
123.8
124.1
123.5
--
125.0
123.1
135.4
126.7
164.3
140.4
126.3
118.9
129.1
137.5
118.3
141.0
138.3
--
--
139.0
123.1
124.9
123.8
200.4
--
133.7
129.8
139.3
126.6
122.3
130.1
122.3
121.6
--
126.1
137.9
150.6
132.5
121.1
117.6
139.2
122.6
--
127.6
124.4
--
128.7
133.0
133.0
127.1
127.1
135.2
133.7
132.4
132.4
168.6
133.7
133.7
133.7
132.7
169.5
132.7
169.2
133.0
133.0
130.1
169.2
--
127.1
--
131.1
169.5
207.4
216.7
128.4
143.2
206.3
136.6
220.3
182.4
261.6
203.6
201.0
243.3
131.0
176.0
--
182.5
169.5
170.1
286.1
177.5
316.0
183.9
210.4
172.5
171.5
203.4
194.6
202.3
161.5
191.9
203.1
203.6
123.8
181.1
181.3
300.4
179.4
294.6
210.1
213.1
--
175.6
153.6
152.8
220.7
174.5
130.4
175.8
121.0
202.9
228.7
280.5
120.9
184.7
143.7
251.3
--
--
278.3
128.4
127.8
182.5
184.7
244.1
216.6
208.8
209.5
--
--
221.5
--
205.8
193.7
187.4
148.7
183.9
229.6
129.9
125.8
173.4
138.5
125.4
126.5
167.2
152.7
113.0
126.1
137.4
154.5
130.8
121.3
138.7
126.2
138.3
126.8
164.7
122.9
124.8
133.5
--
129.7
136.0
129.0
150.2
121.3
127.5
138.6
144.4
134.6
128.5
130.2
105.4
116.7
135.3
197.2
129.6
174.1
156.3
120.3
133.2
126.5
132.3
200.1
150.1
118.0
148.4
167.4
126.3
127.4
130.8
125.7
154.4
163.6
154.2
126.9
141.6
127.7
140.3
125.8
125.3
126.1
162.6
129.3
126.6
149.8
169.3
125.0
125.3
134.8
146.9
119.4
125.9
127.9
132.9
125.7
137.5
171.9
150.8
171.0
200.6
138.5
124.1
124.5
123.0
141.3
133.6
127.1
125.3
159.5
138.9
150.2
152.0
144.0
134.6
152.2
139.9
153.3
133.1
--
130.0
129.1
141.3
135.8
174.0
128.4
148.4
130.7
--
135.0
124.8
135.4
126.4
137.3
--
107.3
140.0
140.9
187.4
136.1
140.9
138.5
127.9
140.7
136.5
109.7
145.1
106.1
136.7
166.4
152.5
127.8
131.3
152.7
127.9
132.3
--
183.4
137.2
123.2
134.8
199.7
117.7
135.9
125.9
132.0
148.7
--
134.9
126.9
126.1
116.2
139.7
145.6
136.1
156.5
135.5
132.1
167.6
264.7
165.8
168.5
131.0
143.8
134.4
230.0
139.1
130.2
152.0
235.0
131.2
148.9
199.0
210.0
130.6
114.9
192.2
126.0
138.4
183.4
184.8
169.6
--
190.2
152.5
124.4
135.4
175.5
138.6
123.2
139.0
174.8
128.7
209.0
148.9
184.3
140.7
186.0
139.0
164.8
184.3
126.1
120.3
164.4
150.9
133.3
--
152.3
153.2
141.3
133.3
152.0
133.9
139.9
126.5
130.7
169.3
175.6
199.6
151.3
187.0
154.8
134.6
147.6
209.0
134.6
139.2
128.0
163.4
198.6
157.6
175.3
247.3
162.0
133.2
204.2
131.1
154.0
147.5
131.2
170.2
172.5
217.8
--
173.9
127.6
135.9
186.2
132.1
129.6
149.1
217.8
188.0
146.7
211.9
145.1
177.2
--
125.0
139.6
--
129.1
207.8
178.2
--
--
116.5
179.1
129.3
132.5
134.5
--
122.2
149.6
193.1
143.7
127.1
144.0
168.5
209.7
163.5
172.4
124.8
--
186.0
164.4
132.8
150.2
142.1
--
129.9
137.2
173.4
149.6
125.7
--
137.7
136.1
189.3
131.9
169.3
128.7
127.1
135.3
--
165.3
208.1
--
150.9
143.8
198.6
153.9
174.1
131.3
133.2
136.7
186.4
175.6
140.0
127.8
162.3
136.1
235.0
127.7
--
122.3
122.9
142.3
136.4
127.4
152.8
118.0
140.2
139.8
134.4
125.4
146.7
134.6
212.9
--
130.3
158.6
245.9
137.6
128.7
167.3
125.4
130.5
146.7
139.0
125.8
123.4
246.2
--
193.3
155.4
122.9
233.8
174.3
125.1
145.0
154.9
--
193.7
133.7
344.7
--
--
177.0
134.6
152.3
153.5
132.2
--
127.1
110.5
131.1
132.1
197.0
121.6
--
147.5
--
113.3
116.6
157.8
127.8
125.9
113.3
250.3
140.7
114.6
145.7
126.4
125.9
123.5
132.5
164.8
133.1
148.3
126.8
127.1
143.0
144.2
--
136.2
150.2
136.7
147.5
122.1
145.2
130.7
131.9
112.9
144.2
150.7
202.5
131.2
135.6
134.3
114.0
126.8
--
125.5
134.2
126.4
--
123.9
131.8
--
--
125.4
140.8
--
142.0
136.0
147.7
135.1
143.5
127.2
129.8
--
--
142.0
145.4
127.2
195.2
127.8
121.9
127.3
138.8
143.6
122.5
142.6
145.0
136.0
134.7
--
127.1
158.1
--
--
144.6
135.2
126.8
126.0
143.0
--
133.0
129.0
126.4
153.3
129.6
135.5
152.3
121.7
128.0
144.8
131.0
131.8
124.7
122.3
132.1
127.0
128.7
128.9
--
126.7
126.8
140.1
131.2
169.3
145.8
132.9
122.4
137.2
147.1
114.6
150.0
150.3
--
--
146.8
129.2
130.6
129.3
207.2
--
142.9
138.6
147.9
132.0
127.9
136.3
128.6
124.3
--
133.7
145.3
155.2
137.0
116.4
123.6
148.6
128.6
--
130.7
127.7
--
134.6
139.4
139.4
133.1
133.1
142.3
139.1
133.1
133.1
172.7
139.1
139.1
139.1
138.5
174.3
138.5
174.1
139.4
138.6
134.6
174.1
--
133.1
--
132.1
174.3
212.0
220.0
135.7
146.7
210.4
139.7
220.4
184.6
261.4
202.0
201.8
248.8
134.7
184.9
--
184.7
176.7
171.4
286.7
187.4
316.7
190.8
210.7
175.1
174.4
206.1
195.1
203.9
163.1
193.3
204.6
202.0
129.3
186.1
183.1
301.5
181.6
294.0
214.9
214.8
--
179.3
156.2
158.5
222.3
176.4
137.6
184.9
126.5
200.0
235.4
280.6
127.3
191.2
150.8
252.3
--
--
277.2
134.8
134.4
184.7
186.6
247.2
223.1
209.1
214.6
--
--
224.1
--
207.1
197.0
196.1
151.5
191.9
229.6
131.3
122.4
172.9
136.9
124.2
119.9
168.6
152.0
105.2
128.1
130.0
153.0
133.0
121.0
139.1
123.8
138.3
125.5
159.1
124.2
120.7
131.5
--
130.9
134.2
132.5
147.7
119.4
129.2
138.4
142.6
133.5
126.2
129.0
105.4
121.4
133.4
195.7
123.0
166.1
155.0
120.9
127.5
123.6
126.4
197.7
150.1
119.6
148.6
167.4
125.3
125.1
133.1
125.3
152.9
162.8
155.0
123.1
141.4
125.6
140.1
119.8
126.7
128.1
162.8
122.3
125.6
147.7
163.5
126.7
126.7
135.2
145.7
117.2
127.6
126.3
125.7
125.4
133.0
171.3
143.8
169.6
197.0
137.1
120.3
120.9
123.0
141.5
134.1
123.5
121.8
158.5
134.9
147.7
152.5
145.2
135.7
150.0
135.3
153.8
132.5
--
128.3
127.3
136.7
133.4
173.5
123.3
148.6
131.6
--
130.7
122.2
132.7
123.3
131.8
--
109.5
135.6
135.1
187.0
131.1
140.3
132.8
128.9
139.5
132.7
115.2
142.2
106.3
136.9
159.9
150.3
127.2
129.4
152.0
128.9
134.1
--
176.0
133.5
120.6
135.2
202.2
120.1
136.5
124.0
128.8
150.0
--
134.8
126.0
125.0
118.4
140.1
144.0
136.4
158.2
136.1
131.0
162.2
263.4
157.3
168.8
131.4
142.4
134.6
230.4
138.6
129.0
152.5
234.9
126.9
145.7
198.3
211.1
130.5
117.5
191.3
125.7
137.8
183.5
183.5
169.0
--
188.7
153.0
123.1
135.0
174.6
138.4
120.6
134.1
173.4
129.5
209.8
145.7
185.8
138.8
187.2
134.6
163.7
184.7
125.2
120.9
164.2
148.6
129.1
--
153.6
154.4
139.2
129.1
152.5
134.5
134.7
123.6
131.9
169.2
173.8
196.9
152.3
188.1
155.4
131.5
149.3
209.8
133.0
134.8
128.5
162.3
196.6
157.3
174.3
246.5
156.7
127.5
209.5
127.4
150.0
147.3
126.9
169.0
171.5
219.3
--
172.7
125.5
136.5
184.5
131.0
123.0
142.6
219.3
188.0
145.0
212.5
144.7
178.2
--
122.0
130.4
--
125.0
212.9
177.4
--
--
119.0
177.9
130.6
131.6
126.8
--
118.1
150.9
190.3
142.6
125.4
134.0
168.8
208.6
154.9
172.0
122.2
--
187.2
156.3
129.9
147.7
141.0
--
126.1
137.5
172.9
149.4
124.6
--
137.7
136.4
189.7
126.8
169.2
128.0
127.5
133.4
--
156.9
208.4
--
148.5
142.4
196.6
153.3
173.7
132.4
133.9
136.9
188.3
173.8
140.3
127.2
161.8
128.7
234.9
124.9
--
119.6
124.2
142.2
136.7
121.5
153.0
119.6
134.4
138.3
134.6
124.2
145.0
133.0
212.1
--
130.4
158.4
244.3
138.9
124.9
166.2
124.2
125.5
141.7
134.6
123.0
123.6
245.0
--
191.8
156.6
120.5
233.5
174.6
122.8
144.1
154.3
--
191.9
134.1
344.8
--
--
177.5
132.4
153.6
154.2
131.1
--
126.9
108.4
128.9
129.9
193.5
120.1
--
140.8
--
121.7
117.6
152.5
122.6
126.9
121.7
249.4
135.3
119.0
138.9
128.6
123.0
118.4
132.4
165.2
132.8
138.8
125.7
125.4
138.7
138.6
--
135.2
150.3
136.9
146.6
117.1
136.0
128.4
128.5
118.2
134.4
144.0
206.1
129.1
129.6
131.1
116.6
125.7
--
119.7
130.0
118.0
--
121.5
132.1
--
--
118.5
137.5
--
138.1
132.5
143.7
133.6
137.7
128.1
127.0
--
--
139.0
139.8
126.6
194.0
122.6
118.5
122.4
137.2
138.9
120.1
136.3
137.6
128.5
133.1
--
127.1
146.7
--
--
140.8
133.8
125.5
129.4
138.7
--
129.4
128.0
121.1
153.0
129.4
131.0
147.4
120.3
127.2
146.2
132.9
133.3
122.2
120.6
133.2
127.1
124.5
125.5
--
125.5
126.7
141.6
130.5
167.1
146.0
128.3
120.0
133.7
143.7
119.1
146.0
144.0
--
--
140.7
124.7
128.6
127.0
203.1
--
139.2
131.2
140.8
132.3
124.0
132.0
126.3
122.7
--
127.5
143.6
154.8
125.6
122.8
122.0
144.8
128.8
--
131.5
127.1
--
134.2
137.0
137.0
127.5
127.5
133.9
137.1
131.6
131.6
171.9
137.1
137.1
137.1
132.8
173.8
132.8
173.7
137.0
138.4
128.8
173.7
--
127.5
--
130.7
173.8
205.2
217.9
132.5
144.7
208.9
138.0
221.0
189.5
265.8
206.1
203.1
249.2
134.3
178.1
--
189.5
168.5
176.0
283.1
181.3
317.5
187.5
212.0
179.5
178.4
205.9
194.9
197.9
166.7
198.4
209.8
206.1
127.0
189.3
187.9
302.0
185.4
297.0
206.9
214.7
--
182.0
159.4
159.4
222.2
174.5
131.2
182.7
122.1
204.8
231.6
277.8
122.8
191.9
150.1
252.1
--
--
280.8
133.2
132.4
189.5
191.4
242.0
214.0
213.9
206.3
--
--
220.0
--
212.2
196.7
192.3
152.2
183.9
224.7
124.3
125.0
165.9
127.0
120.7
117.7
160.1
143.8
104.1
118.8
124.0
147.4
130.2
118.0
132.5
120.4
130.5
120.8
153.3
121.1
116.2
128.3
--
122.4
127.3
132.3
143.9
122.5
132.1
130.7
134.5
124.6
126.0
125.3
106.8
122.9
130.3
193.2
119.7
164.2
150.2
117.0
120.5
120.8
120.6
195.6
141.1
116.5
143.5
160.4
122.6
118.4
132.0
125.9
147.1
153.9
148.4
120.5
133.1
120.1
134.3
114.4
117.4
118.8
157.2
119.0
121.0
139.0
157.8
119.2
117.4
130.4
138.9
117.3
120.9
123.5
122.2
121.5
131.4
165.5
138.4
165.5
193.0
127.6
119.2
122.1
120.3
134.6
125.3
121.6
120.2
154.4
125.6
143.9
144.3
136.3
127.4
145.5
131.5
146.2
122.9
--
127.6
124.2
131.4
130.4
167.0
126.4
143.5
124.0
--
124.1
125.3
126.6
120.2
130.5
--
108.4
131.7
131.9
179.5
129.2
134.8
130.4
122.9
132.6
125.5
114.3
137.8
107.8
128.9
158.1
146.0
123.2
124.1
143.8
122.9
127.8
--
172.1
130.2
121.6
130.4
199.2
121.5
127.4
120.0
121.8
141.0
--
126.0
118.5
120.9
121.4
133.7
136.3
130.8
149.5
128.4
127.5
155.8
264.5
156.9
162.5
123.0
132.7
129.4
225.9
131.3
125.3
144.3
231.3
125.3
140.7
193.7
209.2
127.6
118.3
189.1
121.1
129.0
176.9
178.8
164.1
--
186.7
143.6
120.4
127.1
167.3
130.7
121.6
136.4
166.8
124.3
207.0
140.7
180.4
133.2
181.1
131.0
159.9
180.1
119.7
117.0
158.6
148.4
122.8
--
145.1
147.8
130.6
122.8
144.3
125.6
136.0
120.8
123.6
163.3
167.4
186.9
143.2
179.7
147.7
130.1
142.7
207.0
132.0
133.0
123.9
157.0
190.7
148.2
166.5
242.6
152.8
120.5
198.6
125.0
151.6
140.4
125.3
160.8
164.8
219.1
--
166.4
122.7
127.4
182.8
127.5
119.7
140.0
219.1
181.4
138.2
209.6
135.0
171.9
--
120.8
123.6
--
125.0
198.1
173.5
--
--
123.7
171.3
123.8
126.9
130.2
--
119.3
146.3
184.0
136.2
120.7
126.5
162.5
208.0
152.0
164.1
121.1
--
181.1
154.6
129.2
143.9
132.9
--
121.4
130.5
165.9
144.5
121.4
--
129.9
130.8
185.0
126.9
163.3
123.5
125.3
130.5
--
154.0
202.6
--
144.8
132.7
190.7
146.7
167.1
131.7
129.5
128.9
182.0
167.4
133.8
123.2
161.0
125.9
231.3
123.1
--
120.8
121.1
135.1
134.7
120.3
147.7
116.5
131.5
129.0
129.4
120.7
138.2
132.0
206.8
--
121.2
151.8
243.0
131.9
129.8
158.4
120.2
125.1
138.7
131.1
123.6
120.9
246.3
--
188.1
150.9
119.1
226.8
169.4
122.8
136.1
145.0
--
188.3
126.2
342.3
--
--
171.6
125.8
145.1
145.9
124.5
--
121.3
112.2
124.9
128.9
188.9
120.0
--
134.0
--
119.9
122.1
153.2
116.9
125.0
119.9
248.6
136.0
120.1
132.9
126.5
121.8
115.8
126.8
158.5
127.0
135.4
121.0
120.7
132.7
132.2
--
129.5
144.6
128.9
142.0
115.3
135.5
119.7
121.2
118.5
132.4
138.5
200.8
127.5
126.9
128.9
117.9
121.0
--
116.4
124.0
119.3
--
119.5
125.5
--
--
115.6
129.7
--
132.9
135.4
142.7
125.8
132.5
126.6
122.2
--
--
133.7
135.8
120.2
188.8
116.9
117.2
120.7
131.0
136.0
118.9
132.5
136.5
125.4
126.3
--
127.5
140.9
--
--
133.2
125.9
122.8
127.9
132.7
--
123.5
119.3
118.9
149.4
125.5
122.7
147.9
120.3
118.4
138.8
125.8
125.2
121.1
120.7
125.7
124.4
128.3
124.1
--
124.0
123.6
134.0
124.7
162.6
139.6
125.5
119.1
126.6
137.9
119.6
139.2
136.9
--
--
137.4
120.4
124.0
124.8
198.8
--
131.7
130.0
138.2
126.7
121.1
129.6
120.9
122.7
--
125.3
136.7
150.8
136