We treat tinnitus

Advanced center of tinnitus reduction and hearing loss treatment

What makes us special?

Four technologies of tinnitus reduction

Advanced technologies of hearing loss treatment with multisensory

and musical training

Advanced technology of diagnosing tinnitus type and

nervous system activity

About us

Our facility is leading the world in terms of connecting medical consultations, diagnostics and treatment with the world of audiology and neurobiology. Hearing constitutes 80% of the nervous system; therefore, all kinds of issues regarding tinnitus, disorders of cognitive processes, reorganization and deprivation of hearing concern the nervous system itself. While everyone is trying to find an answer in audiology, we have already found it in neurobiology. It’s the main reason for us being successful in an effective treatment of tinnitus, hearing loss, disorders of cognitive processes, depression and schizophrenia. In 2014 in Warsaw, we opened our very first clinic and in 2015 in Bydgoszcz, we opened our second clinic. Future clinics will be located in China, Germany, France and the USA. We want to share our passion and what we have discovered with everyone.

Diagnostics in our clinics

In our clinics, we provide individual approach to each tinnitus patient. We realize that the nervous system of a patient who has been suffering from tinnitus for 2 years is different from a patient with 6-year experience. It’s connected with plasticity of the nervous system. That’s why we use specialized program of choosing technology to a plasticity model which causes tinnitus in the nervous system. Each patient has a number of medical tests performed starting from high frequency audiometry in the range between 125 Hz to 20 kHz towards diagnostics of sudden hearing loss, testing for activity of the nervous system, examination of the horizontal fibers of the auditory cortex and hyperactivity of the corpus callosum fibers. Those tests examine deep structures of the nervous system. We are trying to foresee consequences caused by sudden hearing loss which encouraged hyperactivity of the nervous system (tinnitus). The next step is choosing technology to a diagnosed model and changes that occurred.

An exemplary path of diagnostics in our clinic

1. Hearing tests 2. Neurodiagnostics 3. Test for plasticity type that occurred in the nervous system

High frequency tonal audiometry test in the range of 125 Hz to 20kHz

ABR/ ASRR test in search of hidden hearing loss

Why we are able to reduce tinnitus and other clinics can’t?

Thanks to advanced technology we are able to diagnose one of four plasticity models which occurred in a tinnitus patient. After having our tinnitus patient diagnosed with one of four models, we choose the most effective treatment. Thanks to this approach we know which technologies we should use and which ones will bring no results at all.

Tinnitus up to 4 years

Enhanced synchronization of neurons

Tinnitus up to 2 years

Spontaneous activity of synapses

Tinnitus above 4 years

Hyperactive horizontal fibers of the auditory cortex

Hyperactive corpus callosum fibers – tinnitus caused by acoustic trauma

Enhacedsynchronization

Spontaneousactivity

Hiperactive horizontal fibers structure

Hiperactivecorpus callosum

Our technologies – brief description of what we discovered

Transcranial stimulation rTMS is now used in many countries in depression and schizophrenia treatment. This technology was tested also in terms of tinnitus treatment. As it turned out, it is highly effective in tinnitus reduction up to 90% when used with enhanced synchronization of the auditory cortex neurons. This technology is used in our clinics for tinnitus patients who’s been suffering for over 2 years. Their cells from the range of hearing loss are not stimulated properly and they lose connections with the auditory cortex neurons. Neurons are trying to find different source of stimulation. Then, a huge population of neurons which lacks stimulation from the cells of the hearing loss range connects with neurons and fibers which have access to the stimulation with healthy cells. In this way, a region of neurons which analyze audible signal is too big; it also emerges as hypersensitivity to too loud sounds.

rTMS stimulation and its effectiveness matching the cause of tinnitus: enhanced synchronization

Simplified model Simplified model

Neurons

Auditory cell Auditory cell

Neurons

Hyperactive synapses in patient with tinnitus lasting 2 years

Hyperactive synapses in patient with tinnitus above 2 years

The picture presents two models of generating tinnitus. Within first two years, synapses remain hyperactive; however, due to lack of stimulation they connect with other cells which work properly. This kind of plasticity occurs in tinnitus patients with an experience from 2 to 6 years. In order to reduce tinnitus in such a case, we have to use rTMS technology to depolarize neurons. Acoustic stimulation could bring effects, but the stimulation process will surely last longer.

Synaptic Adaptation Arc Therapy - this particular therapy was created by us on the basis of our experience and individual approach to each patient. This therapy focuses on sound stimulation of the inner ear region where auditory cells died suddenly. When sudden hearing loss emerges, the nervous system consisting of neurons is unable to adapt to change of stimulation so fast and it remains unchanged (how it was before hearing loss occurred). It results in natural increase of activity in the inner ear region where hair cells died suddenly; thus, our hearing gets worse. When the nervous system notices lack of stimulation from the cells afflicted by sudden hearing loss, it boosts its activity. Hearable shriek or different, characteristic sound (tinnitus) is a result of synaptic hyperactivity. It’s the first model which appears in patients with tinnitus lasting up to 2 years. There is no such technology in the world which could reduce tinnitus to this particular model. For this reason, we have created our own technology - Synaptic Adaptation Arc Therapy, and we patented it. This technology uses the process of adaptation of the nervous system to receiving gradually weaker stimulation with production of cytoskeletal protein Arc/ Arg 3.1 (it is naturally produced within escalating hearing loss). That is why patients with gradually developing hearing loss does not suffer from tinnitus. Their nervous system produces Arc/ Arg 3.1 protein, and adjusts its size and activity to the stimulation level. When sudden hearing loss emerges, the nervous system cannot adjust its structure to sudden deterioration of hearing. That is why patients with sudden hearing loss experience tinnitus (hyperactivity of the nervous system). Our technology was created to deal with this problem by using Synaptic Adaptation Arc Therapy. This technology uses acoustic stimulation which declines within time and it causes exactly the same reaction which appears in sudden hearing loss. Also, this technology encourages the production of Arc/ Arg 3.1 protein which then adjusts the size and activity of synapses and neurons to the stimulation decreasing within time. We tend to use this technology to the spontaneous synaptic activity model which always emerges within first years after tinnitus had occurred.

Synaptic Adaptation Arc Therapy and its effectiveness, matching the cause of tinnitus: spontaneous activity of synapses

Simplified model

Neurons

Auditory cell

Normal hearing

The picture presents properly working auditory system where fibers and neurons are connected with every cell. During sudden death of outer auditory cells, activity of synapses is increased. Synapses no longer receive stimulation from inner auditory cells. In this way, each tinnitus patient has a model of spontaneous synaptic activity developed at the very first stage of the illness. In order to reduce this tinnitus model, Synaptic Adaptation Arc Therapy has to be used.

Hyperactive synapses in patient with tinnitus lasting 2 years

Sudden death of auditory cells

NeuronHyperactive synapses in patient with

tinnitus lasting 2 years

Simplified model

Sudden death of auditory cells

Neuron

Simplified model

Acoustic Neuromodulation CR therapy

This therapy has already been in use in Germany, England and Poland. Its aim is to reduce hyperactive fibers between neurons of the auditory cortex. Along with sudden hearing loss occurs lack of balance in terms of activity between stimulating and hampering neurons. Large neural population of the auditory cortex which lacks sudden hearing loss increases its activity by horizontal connections with hyperactive synaptic structure of neurons with sudden hearing loss. For this plasticity model and tinnitus type we select acoustic neuromodulation therapy. The therapy is also acoustic stimulation with scientific algorithm elaborated by German scientists.

Acoustic Neuromodulation CR therapy and its effectiveness, matching the cause of tinnitus: hyperactive horizontal fibers of the auditory cortex

Hyperactive horizontal fibers Hyperactive horizontal fibers

Musical training

Brain Volts is a laboratory in Northwestern university. A great amount of research published there covers the area of influence music has on the nervous system, neurons’ reaction and plasticity. When sudden hearing loss caused by acoustic trauma occurs we often observe that only one ear suffers from sudden hearing loss (as audiogram shows) whereas the other has no visible cell damage. For this particular model we use musical training. Neurons from the auditory cortex often simultaneously analyze sound and somatosensory stimulation. It has been proved that playing a musical instrument increases the number of hampering neurons (they change electric potential from high to low). That’s why rebuilding neurons by playing an instrument is so effective. When auditory cortex and visual cortex are stimulated with sound in terms of their memory activity, it will cause crossed stimulation of pyramidal neurons from the auditory cortex. It means the neurons will be rebuilt. Along with musical training, the patient is obliged to follow diet requirements which increase glycerin level, neurotransmitter GABA and BDNF neurotrophic proteins. The last of those three is responsible for speeding up the process of rebuilding neurons and making communications between neurons easier.

Musical training and effectiveness matching the tinnitus cause: hyperactive corpus callosum fibers from the auditory cortex

Standards we establish today will become standards of every clinic responsible for tinnitus reduction and hearing loss treatment all over the

Hyperactive corpus callosum synapses

Neurons of the right auditory cortex

Damaged neurons

Corpus callosum fibers

Neurons of the left auditory cortex

Neurons of the healthy auditory cortex which receive spontaneous electric potential from synapses without

Most common mistakes in tinnitus diagnostics and consultations made by other clinics

Insufficient consultation

Basic hearing diagnostics without performing the most important test – high frequency tonal audiometry and without conducting tests for the nervous system

Selecting one technology to each medical case without diagnostics and knowing various plasticity types; therefore, not knowing generated tinnitus

Neglecting diet and physical activity which might be helpful in influencing effective treatment with therapy stimulation by using the most important proteins of the nervous system – BDNF – NT 3 Serotonin

Our golden rule and unusual approach which makes us irreplaceable

Our approach

Initial consultation At first, we determine model of generated tinnitus taking into consideration physical activity, alcohol, environment, diet and time of the day and how it influence tinnitus intensity

DiagnosticsExtended hearing tests, examination of the nervous system to diagnose tinnitus model. In order to confirm tinnitus model we perform at least two neurodiagnostic tests.

Repeated medical consultationDiscussing test results, graphic and visual explanation of tinnitus model and its cause, qualifying a patient for a therapy, diet consultation.

Following diet and physical activity requirements A patient has to follow diet and physical activity requirements, because it will create appropriate conditions to start a therapy (selected on the basis of previous diagnostics).

Begining a therapy If a patient noticed he/ she has become more resistant to stress, tiredness and tinnitus has been muted, it means all proteins necessary to begin a therapy have been regulated.

Introduction of our clinics

Warsaw

In our medical center in Warsaw we have Audiologist’s Room where tinnitus patients are substituted with prostheses and where their cochlear implant processors are regulated. We are one of a few clinics in Poland and Europe which uses tests for auditory sensory memory and short-time memory. Also, we perform tests for audio-visual dynamics to choose an appropriate hearing aid model for our patient. In our clinics we provide SeboTek hearing aids (the only ones on the market with the wide amplification range up to 16 kHz).

Except advanced tinnitus and hearing loss diagnostics we perform hearing tests using ABR and ASSR attention test P300. Those tests are also used to select hearing aids for the youngest patients. Soundproof booth is equipped with the latest technology 3D Tympanometry, ABR, Otoacoustic emission, high-frequency audiometry, test platform of cognitive processes and tinnitus diagnostic platform (platform used to diagnose tinnitus model). Thanks to our specialized equipment we are able to diagnose even the most difficult cases.

In our clinics, we also have Dietician’s Room. Dietician helps us maintain the highest level of therapy effectiveness and stimulation influence on auditory cortex regeneration after hearing loss. What we eat and what kind of diet we keep greatly influences how fast a therapy will bring noticeable results and how fast the structure of the nervous system will be reorganized during post-cochlear implant rehabilitation or after using a hearing aid.

One of the most amazing places in our clinic is a room for musical training, where we help out patients who suffer from sudden hearing loss or acoustic trauma to rebuild damaged structure of the neurons. The aim of the musical training is to use it in the process of reconstructing neurons, and not to make a patient an enthusiast of playing an instrument. Performing musical training for 6 months shortens regeneration time of the auditory cortex neurons from 10 000 hours to 5 000 hours. Some patients decide to continue playing an instrument after the therapy is completed. We develop our hidden talents at different age.

In our clinic you will also find a room equipped with a training program which aims to develop cognitive processes in patients with acoustic trauma, hearing loss and during the process of inserting implants. Thanks to those specialized tests you are able to practise aspects of better speech recognition in noise, sound localization and regeneration of auditory cortex neurons through the stimulation of the parietal lobe and frontal lobe.

There is a specialized chair with electric regulation in our room used for rTMS transcranial stimulations, rTMS Magstim Stimulator and Syneika neuronavigation, for controlling and monitoring the whole process with modern optic visualization.

Bydgoszcz

In our clinic in Bydgoszcz we also perform all available tests connected with hearing diagnostics, cognitive processes, hidden hearing loss, tests for activity of the nervous system and neurodiagnostics. Also, our patients might be a part of EEG brain testing program before a therapy for tinnitus reduction starts. We have the best specialists and measuring equipment of the latest technology.

Except a room for tinnitus reduction equipped with rTMS stimulator and neuronavigation, there is also a room for training and neurobiological rehabilitation with specialized devices. It is then possible to increase the level of BDNF proteins, adaptive protein Arc/ Arg 3.1, to regulate the atrial natriuretic peptide (ANP). It eliminates the risk of creating other factors of ischemia, lack of oxygen in the inner ear and the maze which may lead to recurrent attacks of dizziness and tinnitus.

Each of our clinics provides patients with four technologies of tinnitus reduction. Synaptic Adaptation Arc Therapy is automatically pro-grammed for the whole therapy and that can be done by an audiologist during any appointment. Thus, it’s not necessary for our patient to visit us in the clinic to change settings. The device does that automatically and according to initial set-tings.

Our future?

We are planning to develop our clinics in other countries and to provides services in different ways.

It’s been almost 2 years since our journey started and we have to improve the website because our standards, rules and science develops very rapidly. We are constantly trying to improve our technologies in terms of diagnostics, consultations or treatment itself. We are finding new ways to select therapies and treatment methods more effectively.

Our website, 2014

Our website, 2016

Our website has been modified and it is more clear and easier to use now. Also, we are the only clinic in Poland which provides audiology and laryngology services with two consultation options and clinical diagnostics. We have created our own diagnostics platform and online consultation center. Thanks to this platform our patients are able to decide whether they want to visit us in one of the clinics or consult with the specialist online via videoconference (available after registration). If a doctor suggests medical tests or diet, a patient can go to the ‘Diagnostics’ bookmark at our website and go through the online medical protocol (identical to the one we have in our clinics). The results will show if it’s necessary for a patient to visit us in our clinic.

Thus, we are able to provide services for Polish and foreign patients and it has become easily accessible worldwide. This is a revolutionary program, so it requires time before it becomes a standard way of patient-doctor communication.

Media about us

At our website you will find ‘Media’ bookmark, where we provide information about TV interviews we gave and newspaper articles we appeared in. We surely are innovative and one in a kind, so we attract media attention in the country and abroad.

Adam Pabiś tells us about tinnitus treatment in the morning show ‘Pytanie na Śniadanie’Adam Pabiś described a method used in tinnitus treatment created by Bioacoustic and used in Kinetic Centrum Nowoczesnej Audiologii. Then, he answered viewers’ questions.

Tinnitus – Kurier WarszawskiLastly, we hosted journalists from Kurier Warszawski, TVP Info in our clinic – Kinetic Centrum Nowoczesnej Audiologii. We told them about modern methods of tinnitus treatment.

Innovations for you – Tinnitus in TVPOur medical center had an opportunity to take part in the recording ‘Innovations for you’ in TVP, hosted by Roman Młodkowski. President of the Board of two companies: Bioacoustic and Kinetic Centrum Nowoczesnej Audiologii, Adam Pabiś, told about modern method of tinnitus treatment and development plans. We hope you enjoy watching.

Międzynarodowe gazety:

http://scienceinpoland.pap.pl/en/news/news,406757,silence-the-noise-with-sounds.html

Polish press:

http://pulsinnowacji.pb.pl/4250204,24824,bioacoustic-uciszy-szum-w-uszach http://wyborcza.biz/biznes/1,100896,18966732,cisza-w-uchu-szum-na-rynku-pomysl-29-latka-z-polski-wart-2.html

Nasza autorska terapia adaptacji synaptycznej dostała nawet nominację znanego w Polsce czasopisma naukowego Focus

Mamy w Polsce wielu utalentowanych naukowców i wynalazców. Dwa lata temu wprowadziliśmy w naszym plebiscycie trzy kategorie, w których nominujemy ludzi zaangażowanych w ciekawe projekty badawcze. Ostateczną decyzję dotyczącą wyboru nagrodzonych zostawiamy Wam! Na nominowanych możecie głosować od XXXX do YYYYY 2016 r. za pośrednictwem strony internetowej www.soczewki.focus.pl

INNOWACJE MEDYCZNE

1 IMPLANT DO LECZENIA PRZEPUKLINY

Uczeni z Pomorskiego Uniwersytetu Medycznego i Zachodniopomorskie-go Uniwersytetu Technologicznego stworzyli implant ułatwiający operowanie przepuklin. Płynny polimer po wstrzyknięciu do organizmu zamienia się w gąbczastą substancję, wzmacniającą osłabione miejsce. Zabieg ma trwać tylko pół godziny.

2 PŁYN DO PRZECHOWYWANIA NARZĄDÓW

Naukowcy związani ze Śląskim Uniwersytetem Medycznym opracowali nowy płyn do przecho-wywania narządów pobranych do przeszczepu: serca, wątroby, trzustki lub nerek. Biolasol jest o połowę tańszy niż jego zagraniczne odpowiedniki. Na rynek wprowadziła go firma Biochefa. Więcej: www.biochefa.pl

3 ŚWIETLNY POMIAR POZIOMU GLUKOZY

Aby zmierzyć poziom glukozy u chorego na cukrzycę trzeba dziś pobrać krew. Grupa studentów Wojskowej Akademii Technicznej w Warszawie pracuje nad technolo-gią iSULIN, dzięki której badanie jest nieinwazyjne. Wystarczy przystawić palec do czujnika diodowego, a potem odczytać wynik np. na ekranie smartfona.

4 TERAPIA SZUMÓW USZNYCH

Słuchawki połączone z tzw. neuroprocesorem pomagają pacjentom cierpiącym na dokuczliwe szumy uszne. Poprawę widać już po kilku miesiącach stałej terapii. Nowatorską technologię Terapii Adaptacji Synaptycznej Arc opracowali specjaliści z warszawskie-go Centrum Nowoczesnej Audiologii – Kinetic. Więcej: www.kinetic-cna.pl

5 TERMOGRAFICZNE WYKRYWANIE RAKA PIERSI

Firma Braster z Ożarowa Mazowiec-kiego skonstruowała tester do diagnostyki raka piersi. Dzięki technologii termografii kontaktowej można wykryć ogniska komórek nowotworowych, które mają wyższą temperaturę niż zdrowe tkanki. Braster Tester ma być stosowany samodzielnie przez kobiety w domu. Więcej: www.braster.eu

INNOWACJE TECHNICZNE

1 BUTELKA IZOTERMICZNA

Zespół z Politechniki Gdańskiej postanowił ulepszyć termos. W efekcie powstał pojemnik, który pozwala na utrzymanie niskiej temperatury napoju nawet przez kilkanaście godzin. Może mieć dowolny kształt i być wykonany zarówno ze szkła, jak i z plastiku. Jest przy tym tani w produkcji i bezpieczny dla zdrowia.

2 MONITOROWANIE PSZCZÓŁ W ULU

Pszczelarze mają dużo pracy przy doglądaniu pasieki. Pomóc im w tym ma system elektronicznego monitorowania ula, opracowany przez studenta Akademii Górniczo--Hutniczej. Dzięki czujnikom i powiadomieniom SMS pszczelarz będzie wiedział np., kiedy pszczoły zaczynają chorować. Więcej: www.fb.com/ProjektMaja

3 PŁYNNY PANCERZ KULOODPORNY

Kamizelki chroniące przed kulami są najczęściej ciężkie i grube. Polscy naukowcy współpracujący z łódzką firmą Moratex chcą to zmienić, zastępując sztywny materiał cieczą reologiczną, która twardnieje pod wpływem uderzenia. Dzięki temu kamizelki będą wygodniejsze i lżejsze.

4 PORTFEL Z WŁÓKNA WĘGLOWEGO

Jak ochronić zbliżeniową kartę płatniczą przed zdalnym odczytaniem z niej danych? Można zawijać ją w folę aluminiową, ale bardziej stylowym rozwiązaniem jest portfel, który nie przepuszcza fal radiowych. Firma Carbon Workshop wykorzystała w tym celu bardzo wytrzymały materiał, jakim jest włókno węglowe. Więcej: www.carbonworkshop.pl

5 ROBOT KOLEJOWY

Obsługa lokomotyw towarowych i ich wagonów to zadanie trudne i niebezpieczne. Aby zmniejszyć ryzyko wypadku inżynierowie Grupy Zarmen z Chorzowa pracują nad robotem kolejowym, który sam będzie wykonywał manewry, podłączał i odłączał wagony oraz przewoził ładunek na miejsce.

INNOWACJE INFORMATYCZNE

1 LOGOWANIE SIĘ ZA POMOCĄ GŁOSU

Większość z nas cały czas wpisuje hasła w komputerze czy PIN w telefonie. Krakowska firma proponuje alternatywę – rozpoznawa-nie użytkownika po głosie. System może być stosowany w telefonicznych centrach obsługi klienta np. banków czy firm ubezpieczeniowych. Więcej: www.voicepin.com

2 SERWIS DLA MIŁOŚNIKÓW ZWIERZĄT

DingDog pozwala właścicielom psów na poznawanie się i umawianie na wspólne spacery. Możemy sprawdzić na mapie, kto spaceruje z psem w pobliżu lub ogłosić, że sami wybieramy się na przechadzkę. Część zysków z aplikacji ma być przezna-czona na pomoc dla zwierząt (np. w schroniskach). Więcej: www.dingdog.pl

3 SPOŁECZNOŚCIOWE KONKURSY FOTOGRAFICZNE

Serwis Shuttout pozwala miłośnikom fotografii na zarabianie na swoich zdjęciach. Wystarczy je zgłosić do konkursu lub zorganizować własny. Nagrody są finansowane z niewiel-kich opłat za wpisowe, wnoszonych przez każdego uczestnika rywalizacji. Więcej: www.shuttout.com

4 WYKRYWANIE AUTYZMU U DZIECI

Krakowska firma Harimata stworzyła aplikację ułatwiającą rozpoznanie autyzmu u dzieci. Kilkulatek bawi się zestawem prostych gier na tablecie, a program analizuje jego zachowanie. Aplikacja Play.Care przeznaczona jest dla rodziców (wersja dla profesjonali-stów ma pojawić się wkrótce). Jej skuteczność sięga 90 proc. Więcej: www.playcareapp.com

5 ZAKUPY PATRIOTYCZNE

Aplikacja o nazwie Pola potrafi sprawdzić, czy kupowany przez nas produkt pochodzi z polskiej firmy. Po zeskanowaniu kodu kreskowego smartfonem dowiemy się, czy producent opiera się na polskim kapitale, ma zakłady w Polsce i tworzy wykwalifikowane miejsca pracy. Więcej: www.pola-app.pl

Zagłosuj na www.soczewki.focus.plNa głosujących, którzy odpowiedzą na pytanie konkursowe, czekają atrakcyjne nagrody:

Regulamin konkursu na www.soczewki.focus.pl

,15

Focus — Luty 2015

Conferences we prepared

This year, we organized Research and Development Conference for doctors from across the country to share knowledge and experience we have in advanced hearing loss and tinnitus treatment and testing. Conferences took place in three cities: Warsaw, Bydgoszcz and Katowice.

Neurobiologia w audiologiiKonferencje i szkolenia poświęcone tematyce neurobiologii w współczesnej audiologiiConference and training devoted to neuroscience in modern audiology

Neurobiology in audiology

This year we also organized ‘Neurobiology in audiology’ conference – the first conference in Poland where we presented our product for doctors in the whole country, and we trained first clients.

We treat tinnitus