We compare DNA to an encyplopedia (DNA = ) that may not leave the public library .
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We compare DNA to an encyplopedia (DNA = ) that may not leave the public library . 1. How do you get the information out of the library? 2. Accordingly, what needs to happen for using
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We compare DNA to an encyplopedia (DNA = ) that may not leave the public library . How do you get the information out of the library? Accordingly, what needs to happen for using genetic information in the cytoplasm?. Making a protein is like reading a library book. . --------- - PowerPoint PPT Presentation
Transcript of We compare DNA to an encyplopedia (DNA = ) that may not leave the public library .
We compare DNA to an encyplopedia (DNA = ) that may not leave the public library.
1. How do you get the information out of the library?
2. Accordingly, what needs to happen for using genetic information in the cytoplasm?
Making a protein is like reading a library book.
DNA ------------------------------------
Home-work
LibraryNucleus
NeighborhoodCell
Home
Cytoplasm
??
New Protein
Using the information encoded in the DNA:
= “Protein Synthesis”
= “Gene Expression”
Producing Proteins!
From the DNA Code to
the amino-acid sequence of
a Protein
Gene Expression
Building the De-Coding Machine
Making a protein is like reading a library book.
DNA ------------------------------------
Home-work
LibraryNucleus
------------------------------------
------------------------------------
NeighborhoodCell
Central Dogma of Molecular Biology:
Information Flows in One Direction:
DNA RNA Proteins.
Transcription(Nucleus)
Translation(Cytoplasm)
A. Keeping the DNA ‘encyclopedia’ safe in the nucleus.
B. Copying only the necessary information (‘pages’).
C. Only when the information is required.
Transcription:A modified copy of the DNA
The Transcript: RNA
Transcription Translation Lewport
RNA Transcription - from promoter to terminator
Compare Transcription to replication..
lPsCIECNE dna rEPLICATION
Compare DNA to RNA:
DNA and RNA
Bases: ACGT ACGUThymine Uracil
Structure DNA RNA
# of Strands: 2 1
Sugar: Deoxy-Ribose
Ribose
Making a protein is like reading a library book.
DNA = cytoplasm
nucleus
The Gene Expression Machinery:
A. Location in the cellB. Machine PartsC. Reading the Code
The Gene Expression Machinery:
A. Location in the cellB. Machine PartsC. Reading the Code
The Gene Expression Machinery:
A. Location in the cellB. Machine Parts – Transcription to RNA
C. Reading the Code
The Gene Expression Machinery:
A. Location in the cellB. Machine Parts – In The RibosomeC. Reading the Code
Next…
How does it work?
A GCT O AAC
B GCC P CCT
C TGT Q CAA
D GAT R CGT
E GAA S TCT
F TTT T ACT
G GGT U ACC
H CAT V GTT
I ATT W TGG
J ATC X CGC
K AAA Y TAT
L TTA Z TAC
M TTG Start ATG
N AAT Stop TAG
Building the Decoding Machine:ACGTTCCA
ABCDEFGHIJKLMN
