Volume 8, Year 2008, Keyword Index. - · PDF fileFinite-element 379 Flexural Rigidity 401...
Transcript of Volume 8, Year 2008, Keyword Index. - · PDF fileFinite-element 379 Flexural Rigidity 401...
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AAcute Phase Proteins 410Adaptation 10Adipocyte 146Adipokines 346Adrenergic Receptors 105Adrenergic Signaling 94AFM 330Ageing 64Aging 2, 329, 50, 410Alfacalcidol 257Angiogenesis 323Animal and Human Studies 94Animal Models 301Anorexia Nervosa 315Anthropometric Parameters 363Antidepressants 121Atrophy 342Atrophy Target Genes 340
B‚-adrenergic Signalling 111‚-catenin 291B6 71Bcl-3 340Biomechanics of Leg 58BMP4 316Body Weight 146Bone 10, 12, 25, 50, 111, 166, 179, 298, 318, 329, 330, 337,344, 346Bone Adaptation 15, 71Bone Cell Integrins 332Bone Cells 15Bone Density 2, 22, 79, 133Bone Fluid Flow 332Bone Geometry 217Bone Histomorphometry 267Bone Mass 146, 363 Bone Material 29Bone Mechanics 327Bone Mineral Density 217, 315Bone Phenotyping 13Bone Quality 325Bone Regeneration 323Bone Remodeling 2, 29, 94Bone Resorption 251Bone Shape 23Bone Size 217Bone Strength 22, 33, 239, 267Bone Turnover 24Bone-marrow Interface 43
CC3 71Cartilage 307, 308, 321, 337Cartilage Degradation 301Cell Signaling 303CGRP 154Children 24, 25, 217Chondrocyte 303Chondrocytes 307Clinical Research 313Clinical Trials 2Commitment 204Compression 227Computational Mechanics 327Congenic 287Cortical Bone 146Crohn’s disease 79Cross-sectional Muscle Area 239CT 315CTR Polymorphisms 196Cynomologus Monkeys 267Cystic Fibrosis 179Cytokines 301
DD2 71Deformities 58Depression 133Diabetes 346Differentiation 204Diphosphonates 2Distal Tibia 257Distraction Osteogenesis 323Disuse 12DKK-1 296DXA 24, 32, 315
EElbow 391Electrical Stimulation 227Energy Balance 344Energy Dissipation 329Energy Metabolism 351Epidemiology 313Epimedium 18Esp 351Exercise 12, 35, 166Extracellular Matrix 311
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Official Journal of the International Society of Musculoskeletal and Neuronal Interactions
Volume 8, Year 2008, Keyword Index.
419
FFailure Load 401Falls 244Fat 344, 346Fatty (Yellow) Marrow Site 257Females 391Femur 25Fibroblast Growth Factor 318Finite-element 379 Flexural Rigidity 401Fluoxetine 121Forearm Bone Mass 196Fracture 133, 329, 379Fractures 244Functional Adaptation 298
GGender 337Genetics 10, 284, 287Geometrical Variables 196GIP 344, 348GLP 344GLP-2 348Glutamate 166Glycosylated Hemoglobin 188Growth 25, 338Growth Factors 301Growth Plate 29, 308
HHBM 294Hematopoietic (Red) Marrow Site 257Histomorphology 18Histomorphometry 25717‚-Hydroxysteroid Dehydrogenase Type 2 Inhibitor 267Hypertrophy 308, 342Hypoxia Inducible Factor-1· 323
IIGF-1 303IGF1 335IGF-I 342IkappaB Kinases 340IL-1ß 307Ilizarov 32Image Analysis 23In Utero 12Inbred Strain 287Incretin 348Inflammatory Bowel Disease 79, 251Inhibitor of KappaB 340Integrins 303
JJoint 174Joint Position Sense 391
KKnee 313
LLacunar Canalicular Porosity 332Leptin 146, 351Ligament Forces 58Light Orthodontic Forces 375Limb Length Discrepancy 32Liver 410LRP5 284, 291LRP-5 296Lrp5 G171V 294LRP6 291
MMale 196MAP Kinase 311Marrow Sac 43Marrow Stromal Cell 43Master Athletes 64Mathematical Modeling 15Maxillary Cortical Bone 375Maximal Isometric Grip Force 188Mechanical Loading 71, 111, 311Mechanical Strain 298, 338Mechanography 64Mechanostat 298Mechanostat Theory 174Mechano-transduction 15Mechanotransduction 332Memory 166Metabolism 344Metalloproteinases 301Mice 71Micro-angiography 18MicroCT 18microRNA140 321Modeling 29Moment 401Motor Control 174Mouse 13Mouse Clinic 13Msx2 318mTOR 335Muscle 25, 64, 179Muscle Area 33Muscle Derived Stem Cells 316Muscle Power 33Muscle Stem Cells 337Muscle Strength 35, 363 Muscle Wasting 340Muscle-bone 239Muscle-derived Stem Cells 335Musculoskeletal Physiology 64Myoblast 342Myostatin 342
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NNanomechanics 325, 327, 330Neurotransmitter 121NF-kB 335NO 15Nocturnin 344Nuclear Factor of KappaB 340Nutrition 344
OOA 311OC-cre 291Osteoarthritis 22, 35, 301, 307, 313, 316, 391Osteoblast 94, 105, 348Osteoblasts 154, 351Osteocalcin 344, 351Osteoclast 94, 348Osteoclasts 154, 204Osteocyte Processes 332Osteocytes 15, 330Osteonecrosis 18Osteopaenia 251Osteoporosis 2, 22, 50, 79, 105, 121, 133, 174, 179, 204, 267,284, 287Osteoprotegerin 50Ovariectomy 375
PPain 35Peak Bone Mass 196Peak Jump Force 188Peak Jump Power 188Periosteum 29Peripheral Quantitative Computed Tomography 217, 227PGE2 15Physical Activity 363 Post-yield 329PPARÁ 344, 346PQCT 23, 239, 401Preosteoblast 43Pre-pubertal 239Propranolol 111Proprioception 35, 391Protein Synthesis 338Protein Synthesis Rate 410Proximal Femur 257Prozac 121Pyrophosphate 318
QQuantitative Trait 287
RRadiographs 379Rats 375Reactive Oxygen Species 303Rehabilitation 244
Rel Protein 340Risk Factors 2Runx2 318
SS6K1 338Satellite Cell 342Scaling 25Selective Serotonin Reuptake Inhibitors 133SFRP-1 296Skeletal Muscle 337, 410Skeletal Mutations 294Skeleton 24SNS 111SOST/Sclerostin 296SP 154Spinal Cord Injury 50Steroid 18Steroids 24Stiffness 401Strength Indices 401Stress State 58Sympathetic Nervous System 105
TTemporary Brittle Bone Disease 379Tension 227Thiazolidinediones 346Trabecular Structure 315Transgenic 287Transgenic Model 251Transgenic Mouse 311Treatment 204Type II Collagen 308
UUlcerative Colitis 79Ultrastructure 325, 327
VValgosity 58Varosity 58VDR Polymorphisms 196VEGF 316, 323VIP 154von Hippel-Lindau Protein 323VO2max 363
WWhole Body Vibration 179Wnt 291, 296Wnt Signaling 294WWP2 321
ZZinc 22
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AÅhlander, A-C 24Abe, K 13Acosta, F 355Akhter, MP 71Alaql, ZS 323Ali, MN 352Allgöwer, F 15Antonogiannakis, E 196Antvorskov, T 64Anwar, RB 352, 361, 362Anyanwu, J 353Armbrecht, G 179
BBagi, CM 267Baile, CA 146Baker, LRI 355Bamman, MM 342Bartell, SM 146Battaglino, RA 50Behan, M 360Beller, G 179Bérard, J 32Bi, LX 43Binkley, T 33Binkley, TL 239Bliddal, H 391Blimkie, C 25Bliziotes, M 93Block, JA 35Bodine, PVN 296Bonewald, LF 330, 352Bonivitch, AR 330Bonivtch, AR 352Bonnet, N 94Boshof, A 64Bouxsein, M 357Braillon, P 32Bredella, MA 315Breuillé, D 251, 410Brown, RJ 354Bubbear, JS 355Buford, WL 43Bunn, C 356Burr, DB 281
CCao, XM 323Capozza, R 355
Castellini, P 355Causey, RC 360Cerny, EP 58Charopoulos, I 196Chen, HY 257Chen, Q 311Chenu, C 111Chotel, F 32Christensen, H 391Christensen, PH 22Christensen, R 391Christiansen, C 357Ciccomancini, M 357Clemens, TL 291, 323Cockrell, G 356Cointry, G 355Coonse, KG 354Cooper, GM 316Cowell, C 25Coxam, V 251Cross, RA 360Culik, J 58Cullen, DM 71
DDanneskiold-Samsoe, B 391Davicco, M-J 251Davis, SI 355de Bono, S 23Dedoussis, G 196Deng, L 323Dionyssiotis, Y 244Dixon, B 267Dontas, IA 244, 375Dowthwaite, JN 355Dudley-Javoroski, S 227Dusecich, V 330
EEberhardt, AW 323Economides, AN 357Economopoulos, D 244Econs, MJ 284, 357Einhorn, TA 323Ejiri, S 352, 361, 362El Yousfi, M 251Engelke, K 363Esser, K 335, 338
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Volume 8, Year 2008, Author Index.
422
FFarrow, EG 355Feldman, S 355Felsenberg, D 64, 179Feng, JQ 330Ferrari, SL 94Ferretti, JL 355Findeisen, R 15Fosang, AJ 308Fowlkes, J 356Fox, SD 71Franceschi, RT 318Fricke, O 188Fritz, TA 357Fu, FH 316Fuchs, H 13Furmanov, S 35
GGailus-Durner, V 13Galanos, A 196Garshick, E 50Gast, U 64Gauci, SJ 308Gerstenfeld, LC 323Gharaibeh, B 316Gilbert, SR 323Gillespie, M 357Godin, J-P 251Golub, SB 308Goodship, AE 10Grappiolo, I 355Griffith, JF 18Guldberg, RE 323Gundberg, CM 360Guo, XE 325, 327Gupta, R 315
HHadjidakis, D 79Halteman, WA 360Hamrick, M 348Hamrick, MW 146Haney, EM 121, 133Hangartner, TN 379Hans, W 13Hansen, K 391Hatch, NE 318Hausler, KD 357He, X 321Henriksen, K 357, 360Hickman, RM 355Hoeck, HC 22Högler, W 24Hrabe de Angelis, M 13
Huang, L 357Huard, J 316, 337Hui, SL 357
IIchikawa, S 357Inchauspe, G 355Isales, CM 146, 348Iwamoto, J 358
JJacobsen, KA 323Jain, N 50Jakubas, WJ 360Jarret, A-R 410Järvinen, TLN 2Jee, WSS 257Jiang, JX 352Johnston, JD 401Jung, T 64Juul-Kristensen, B 391
KKalender, WA 363Kandarian, S 340Kannus, P 2Karamanolis, DG 79Karlsson, J 24Karsdal, MA 357Karsenty, G 351Keen, R 355Kemmler, W 363Khaldi, L 375Kladny, B 363Klein, RF 287Klibanski, A 315Kobayashi, T 321Kontulainen, SA 401Kopylov, D 353Kroksmark, A-K 24Kuhar, MJ 146Kuruvilla, SJ 71Kvetnansky, R 353Kwiet, A 64Kyriazopoulos, P 196
LLadas, SD 79Lane, N 330Lanyon, L 298Laskey, MA 23Laskey, PJ 23Laursen, MB 22Lecka-Czernik, B 344, 346Lee, ER 308
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Lee, NK 351Lerner, UH 154Lester, G 313Leung, C 401Leung, KS 18Li, B 359Li, G 316Li, J 359Li, M 257Li, Y 35Li, ZR 18Lindvall, C 291Ling, J 352Lisse, T 13Little, CB 308Liu, D 359Liu, D 401Liu, X 358Liu, XQ 257Loeser, RF 301, 303Long, R 360Lumpkin, C 356Lund, H 391Lyritis, GP 196, 244, 375
MMackenzie, DS 357Mackie, EJ 308Magnusson, P 24Mainous, EG 43Makou, M 375Maldonado, S 15Mallas, E 79Marenzana, M 111Marik, I 58Martin, TJ 357Matsumoto, H 358Matsumoto T, 316Mayot, G 410McKay, HA 401McNamara, LM 332Mermoud, A-F 251Meszaros, LB 316Michaelis, I 64Miletic, V 360Miller, KK 315Miller, ME 379Misra, M 315Moh, A 357Moravits, DE 330Morse, LR 50Muir, P 360Murphy, A 357Møller-Madsen, B 22
NNakamura, Y 321Nelson, DE 35Neutzsky-Wulff, AV 357Nguyen, HP 50Nicola, G 355Nicolella, DP 330, 352Nielsen, PT 22Nomura, S 361, 362Nyman, J 356
OObled, C 251, 410Ohshima, H 352, 361, 362Ovesen, J 22Oxford, JT 354Oxland, TR 401
PPanus, DA 357Papet, I 251, 410Patterson-Buckendahl, PE 353Persson, E 154Pierroz, DD 94Postlethwait, JH 321Prentice, A 23
QQin, L 18
RRadice, B 355Ramaswamy, G 323Rao, N 359Rauch, F 25, 29, 217Rawer, R 179Raz, R 357Recker, RR 294Reid, IR 105Reina, P 355Rembitzki, I 179Rittweger, J 64, 174Robling, A 359Rosen, CJ 360Rosen, V 357Roth, J 179
SSakurai, N 362Sample, SJ 360Sandel, LJ 307Sanders, AK 291Scerpella, TA 355Schaffler, MB 332Schiessl, H 1Schnabel, D 179
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Schoenau, E 188, 217Schöffl, I 363Seewi, O 188Seger, RL 360Seger, RM 360Semler, O 188Servello, FA 360Setterberg, RB 257Shah, A 353Shahid, M 353Shakoor, N 35Shaw, CN 23Shen, X 323Sheng, H 18Shields, RK 227Shimakura, T 361Sievänen, H 2Simonsen, O 22Sims, NA 308Skerry, T 12Skerry, TM 166Söderpalm, A-C 24Song, F 359Sorenson, AH 357Spadaro, JA 355Specker, B 33Specker, BL 239Spyropoulos, MN 375Staab, D 179Stabrey, A 188Stamp, TCB 355Stashenko, P 50Stathopoulou, M 196Stocum, D 359Summers, LJ 355Swolin-Eide, D 24
TTakahashi, HE 361Tanaka, M 352, 361, 362Thiele, F 13Thomsen, JS 22Thrailkill, K 356Tian, XY 257Trovas, G 196Tsironi, E 79Tsolakis, AI 375Tulinius, M 24Tun, CG 50Tutlewski, B 188Tutolo, L 308Tzathas, C 79
UUsas, A 316
VValenzuela, DM 357Van Dyke, ME 352VanKoevering, KK 291Varghese, BA 379Vitenzon, A 353von Stengel, S 363
WWagoner Johnson, AJ 358Wahl, E 356Wahn, U 179Wan, C 291, 323Wang, X 329Wang, XL 18Wang, Y 323, 330, 332Wang, YX 18Ward, LM 355Warden, SJ 121, 133Warman, ML 321Watanabe, N 352Weinbaum, S 332White, KE 355Wilkie, D 267Williams, BO 291Williams, S 50Willnecker, J 1Wilson, AP 360Wood, J 267Woodhead, H 25Wust, M 179
XXue, Y 357
YYamamoto, N 361Yamashita, E 352, 361, 362Yan, Y-L 321Yancopoulos, GD 357Yao, W 330Yao, XS 18Yavropoulou, MP 204Yeh, JK 358Yeung, KW 18Yngve, DA 43Yovos, JG 204
ZZhang, G 18Zhu, D 23Zylstra, CR 291
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Official Journal of the International Society of Musculoskeletal and Neuronal Interactions
Aaron, Roy (1)Arnaud, Claude (1)Behrents, Rolf (1)Bergmann, Pierre (1)Bonnet, Nicolas (1)Chenu, Chantel (1)Dale R. Sumner (1)De Vernejoul, Marie-Christine (1)Degens, Hans (3)Dempster, David (1)Devogelaer, Jean-Pierre (3)Diem, Susan (1)Drake, Matthew (1)Dontas, Ismene (2)Elefterious, Florent (1)Ferrari, Serge (1)
Ferretti, José L. (1)Forwood, Mark (1)Goltzman, David (1)Hamrick, Mark (2)Hans, Mark (1)Heinonen, Ari (1)Iwaniec, Urszula (1)Karras, D (1)Ke, Huazhu (1)Kimmel, Don (1)Krohn, Kelly (1)Lu, Shi Shu (1)Mezuk, Briana (1)Mikesky, Alan (1) Moutsatsou, Paraskeui (1)Papavassiliou, Athanasios (1)
Peacock, Munro (2)Rauch, Frank (1)Reeves, Neil (1)Rittweger, Joern (1)Robling, Alex (2)Runge, Martin (1)Seeman, Ego (1)Skelton, Dawn (1)Specker, Bonny (1)Stayrook, Keith (1)Tournis, Symeon (1)Trovas, George (1)Tsezou, Aspasia (1)Weinans, Harrie (1)Yao, Wei (2)Yiannakopoulos, Christos (1)
Volume 8, Year 2008, Reviewer Index.
( ) number of publications reviewed
426
Volume 8, Number 1, January-February-March 2008
ForewordJ. Willnecker, H. SchiesslThe 4th Black Forest Forum for Musculoskeletal Interactions .... 1
Black Forest Forum, May 10-13, 2007, Castle BadLiebenzell, Germany
T.L.N. Järvinen, P. Kannus, H. SievänenBone quality: Emperor’s new clothes ............................................ 2
A.E. GoodshipGenetically modified mechanostats: Implications for skeletal competence? .................................................................................. 10
T. SkerryMechanostat function during skeletal development .................. 12
H. Fuchs, T. Lisse, W. Hans, K. Abe, F. Thiele, V. Gailus-Durner,M. Hrabe de AngelisPhenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic .......................................... 13
S. Maldonado, R. Findeisen, F. AllgöwerDescribing force-induced bone growth and adaptation by a mathematical model ...................................................................... 15
L. Qin, G. Zhang, H. Sheng, X.L. Wang, Y.X. Wang, K.W. Yeung,J.F. Griffith, Z.R. Li, K.S. Leung, X.S. YaoPhytoestrogenic compounds for prevention of steroid-associated osteonecrosis .................................................................................. 18
J.S. Thomsen, P.T. Nielsen, P.H. Christensen, O. Simonsen, H.C. Hoeck, M.B. Laursen, B. MØller-Madsen, J. OvesenDifferences in zinc status, bone turnover and femoral head bonedensity and biomechanical properties between patients with osteoarthritis and osteoporosis .................................................... 22
S. de Bono, M.A. Laskey, C.N. Shaw, D. Zhu, P.J. Laskey, A.PrenticeCould image analysis of pQCT scans provide additional informa-tion about bone strength? .............................................................. 23
A-C. Söderpalm, P. Magnusson, A-C. Åhlander, J. Karlsson, A-K. Kroksmark, M. Tulinius, D. Swolin-EideBone markers and bone mineral density in Duchenne musculardystrophy ........................................................................................ 24
W. Högler, C. Blimkie, F. Rauch, H. Woodhead, C. CowellScaling and adjusting growth-related data and sex-differences in the muscle-bone relation: A perspective ................................ 25
F. RauchHistomorphometric evaluation of skeletal development .......... 29
P. Braillon, F. Chotel, J. BérardLimb lengthening: Contribution of dual energy X-ray absorptiometry ................................................................................ 32
T. Binkley and B. SpeckerMuscle area, muscle mass and muscle power in a pre-pubertal and an elderly population .............................................................. 33
Original ArticlesN. Shakoor, S. Furmanov, D.E. Nelson, Y. Li, J.A. BlockPain and its relationship with muscle strength and proprioception in knee OA: Results of an 8-week home exercise pilot study .... 35
L.X. Bi, E.G. Mainous, D.A. Yngve, W.L. BufordCellular isolation, culture and characterization of the marrow sac cells in human tubular bone .................................................... 43
L.R. Morse, H.P. Nguyen, N. Jain, S. Williams, C.G. Tun, R.A. Battaglino, P. Stashenko, E. GarshickAge and motor score predict osteoprotegerin level in chronicspinal cord injury ............................................................................ 50
J. Culik, I. Marik, E.P. CernyBiomechanics of leg deformity treatment .................................... 58
I. Michaelis, A. Kwiet, U. Gast, A. Boshof, T. Antvorskov, T. Jung,J. Rittweger, D. Felsenberg
Decline of specific peak jumping power with age in master runners ................................................................................ 64
S.J. Kuruvilla, S.D. Fox, D.M. Cullen, M.P. AkhterSite specific bone adaptation response to mechanical loading .. 71
E. Tsironi, D. Hadjidakis, E. Mallas, C. Tzathas, D.G.Karamanolis, S.D. LadasComparison of T- and Z-score in identifying risk factors of osteoporosis in inflammatory bowel disease patients ................ 79
Volume 8, Number 2, April-May-June 2008
ForewordM. Bliziotes ...................................................................................... 93
Review ArticlesN. Bonnet, D.D. Pierroz, S.L. FerrariAdrenergic control of bone remodeling and its implications for the treatment of osteoporosis ...................................................... 94
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Official Journal of the International Society of Musculoskeletal and Neuronal Interactions
Volume 8, Year 2008, Volume Contents.
427
I.R. ReidEffects of beta-blockers on fracture risk .................................... 105
Mini-review ArticleM. Marenzana and C. ChenuSympathetic nervous system and bone adaptive response to its mechanical environment ........................................................ 111
Review ArticlesS.J. Warden and E.M. HaneySkeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: Evidence from in vitro and animal-based studies .. 121
E.M. Haney and S.J. WardenSkeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: Evidence from clinical studies .................................. 133
Original ArticleS.M. Bartell, C.M. Isales, C.A. Baile, M.J. Kuhar, M.W. HamrickCART deficiency increases body weight but does not alter bone strength .......................................................................................... 146
Review ArticlesU.H. Lerner and E. PerssonOsteotropic effects by the neuropeptides calcitonin gene-relatedpeptide, substance P and vasoactive intestinal peptide ............ 154
T.M. SkerryThe role of glutamate in the regulation of bone mass and architecture .................................................................................. 166
Mini-review ArticleJ. RittwegerTen years muscle-bone hypothesis: What have we learned so far? -Almost a Festschrift- .................................................................... 174
Original ArticlesJ. Roth, M. Wust, R. Rawer, D. Schnabel, G. Armbrecht, G. Beller, I. Rembitzki, U. Wahn, D. Felsenberg, D. StaabWhole body vibration in cystic fibrosis – a pilot study .............. 179
O. Fricke, O. Seewi, O. Semler, B. Tutlewski, A. Stabrey, E.SchoenauThe influence of auxology and long-term glycemic control on muscle function in children and adolescents with type 1 diabetesmellitus .......................................................................................... 188
I. Charopoulos, G. Trovas, M. Stathopoulou, P. Kyriazopoulos, A. Galanos, G. Dedoussis, E. Antonogiannakis, G.P. LyritisLack of association between vitamin D and calcitonin receptorgene polymorphisms and forearm bone values of young Greekmales .............................................................................................. 196
Volume 8, Number 3, July-August-September 2008
Original ArticlesM.P. Yavropoulou and J.G. YovosOsteoclastogenesis - Current knowledge and future perspectives .............................. 204
F. Rauch and E. SchönauPeripheral quantitative computed tomography of the proximal radius in young subjects – New reference data and interpretation of results ........................................................................................ 217
S. Dudley-Javoroski and R.K. ShieldsAsymmetric bone adaptations to soleus mechanical loading after spinal cord injury ................................................................ 227
T.L. Binkley and B.L. SpeckerMuscle-bone relationships in the lower leg of healthy pre-pubertal females and males .................................................. 239
Review ArticleY. Dionyssiotis, I.A. Dontas, D. Economopoulos, G.P. LyritisRehabilitation after falls and fractures ...................................... 244
Original ArticlesI. Papet, M. El Yousfi, J-P. Godin, A-F. Mermoud, M-J. Davicco, V. Coxam, D. Breuillé, C. ObledHLA-B27 rats develop osteopaenia through increased bone resorption without any change in bone formation .................... 251
X.Y. Tian, X.Q. Liu, H.Y. Chen, R.B. Setterberg, M. Li, W.S.S. JeeGreater efficacy of alfacalcidol in the red than in the yellow marrow skeletal sites in adult female rats .................................. 257
C.M. Bagi, J. Wood, D. Wilkie, B. DixonEffect of 17‚-hydroxysteroid dehydrogenase type 2 inhibitor onbone strength in ovariectomized cynomolgus monkeys ............ 267
Volume 8, Number 4, October-November-December 2008
ForewordD.B. BurrThe 38th International Sun Valley Workshop on Skeletal Tissue Biology ................................................................ 281
Genetics of Osteoporosis SessionSummaryM.J. EconsIntroduction to skeletal genetics ................................................ 284
R.F. KleinGenetics of osteoporosis – Utility of mouse models ................ 287
C.R. Zylstra, C. Wan, K.K. VanKoevering, A.K. Sanders, C. Lindvall, T.L. Clemens, B.O. WilliamsGene targeting approaches in mice: Assessing the roles of LRP5 and LRP6 in osteoblasts .................................................. 291
R.R. ReckerAutosomal dominant high bone mass: The phenotype. A brief description ...................................................................... 294
P.V.N. BodineTurning genetic discoveries into new treatments: The Wnt/LRP-5 system as a source of new drug targets for skeletaldiseases .......................................................................................... 296
428
RIB Award / Plenary SessionL. LanyonStrain-related control of bone (re)modeling: objectives, mechanisms and failures .............................................................. 298
Translational Research in OA - From Molecules to Animalsto Humans SessionSummaryR.F. LoeserTranslational research in osteoarthritis - From molecules to animals to humans ........................................................................ 301
R.F. LoeserMolecular mechanisms of cartilage destruction in osteoarthritis ................................................................................ 303
L.J. SandellMetabolism of chondrocytes in osteoarthritis: Why all this activity? .................................................................... 307
S.J. Gauci, S.B. Golub, L. Tutolo, C.B. Little, N.A. Sims, E.R. Lee, E.J. Mackie, A.J. FosangModulating chondrocyte hypertrophy in growth plate and osteoarthritic cartilage ................................................................ 308
Q. ChenMouse models and new therapeutic targets for OA ................ 311
G. LesterClinical research in OA – the NIH Osteoarthritis Initiative .......... 313
ASBMR / Harold M. Frost Award PresentationsM.A. Bredella, M. Misra, K.K. Miller, A. Klibanski, R. GuptaTrabecular structure analysis of the distal radius in adolescent patients with anorexia nervosa using ultra high resolution flat panel based volume CT .............................................................. 315
T. Matsumoto, G.M. Cooper, B. Gharaibeh, L.B. Meszaros, G. Li, A. Usas, F.H. Fu, J. HuardBlocking VEGF as a potential approach to improve cartilage heal-ing after osteoarthritis .................................................................. 316
N.E. Hatch and R.T. FranceschiFGF2 induced expression of the pyrophosphate generating en-zyme, PC-1, is mediated by Runx2 and Msx2 ............................ 318
Y. Nakamura, X. He, T. Kobayashi, Y-L Yan, J.H. Postlethwait,M.L. WarmanUnique roles of microRNA140 and its host gene WWP2 in cartilage biology ............................................................................ 321
C. Wan, S.R. Gilbert, Y. Wang, X.M. Cao, X. Shen, G. Ramaswamy, K.A. Jacobsen, Z.S. Alaql, L.C. Gerstenfeld, T.A. Einhorn, A.W. Eberhardt, L. Deng, R.E. Guldberg, T.L. ClemensRole of hypoxia inducible factor-1· pathway in bone regeneration .................................................................................. 323
Nanomechanics of Bone SessionSummaryX.E. GuoNanomechanics and bone tissue quality .................................... 325
X.E. GuoWhat is nanomechanics of bone and why is it important? ............ 327
X. WangThe post-yield behavior of bone: From nano to macroscopic length scales .................................. 329
D.P. Nicolella, J.Q. Feng, D.E. Moravits, A.R. Bonivitch, Y. Wang, V. Dusecich, W. Yao, N. Lane, L.F. BonewaldEffects of nanomechanical bone tissue properties on bone tissue strain: Implications for osteocyte mechanotransduction .......... 330
Y. Wang, L.M. McNamara, M.B. Schaffler, S. WeinbaumStrain amplification and integrin based signaling in osteocytes ...................................................................................... 332
Muscle Biology Session SummaryK. EsserRegulation of skeletal muscle size, regeneration and repair ........ 335
J. HuardRegenerative medicine based on muscle stem cells .................. 337
K. EsserRegulation of mTOR signaling in skeletal muscle hypertrophy .................................................................................. 338
S. KandarianThe molecular basis of skeletal muscle atrophy – parallels with osteoporotic signaling .......................................... 340
M.M. BammanRegulation of muscle size in humans: Role of myostatin? .......... 342
Bone as an Endocrine Organ SessionSummaryB. Lecka-CzernikBone as an integral part of energy metabolism ........................ 344
B. Lecka-CzernikLocal and systemic functions of bone fat and its contribution to the energy metabolism – The effect of diabetes and obesity on bone .......................................................................................... 346
C.M. Isales and M. HamrickNutritional hormones and the entero-osseous axis .................. 348
N.K. Lee and G. KarsentyReciprocal regulation of bone and energy metabolism ............ 351
Poster abstracts from the 38th Meeting of the International SunValley Workshop on Skeletal Tissue Biology (August 3-6, 2008, Sun Valley, Idaho, USA) ............................ 352
I. Schöffl, W. Kemmler, B. Kladny, S. von Stengel, W.A. Kalender,K. EngelkeIn healthy elderly postmenopausal women variations in BMD and BMC at various skeletal sites are associated with differencesin weight and lean body mass rather than by variations in habitualphysical activity, strength or VO2max ........................................ 363
429
A.I. Tsolakis, L. Khaldi, M. Makou, G.P. Lyritis, M.N. Spyropoulos,I.A. DontasCortical bone response adjacent to applied light orthodontic forces in ovariectomized rats ...................................................... 375
B.A. Varghese, M.E. Miller, T.N. HangartnerEstimation of bone strength from pediatric radiographs of theforearm .......................................................................................... 379
H. Lund, B. Juul-Kristensen, K. Hansen, R. Christensen, H. Christensen,B. Danneskiold-Samsoe, H. BliddalMovement detection impaired in patients with knee osteoarthritis compared to healthy controls: A cross-sectional case-control study .......................................... 391
S.A. Kontulainen, J.D. Johnston, D. Liu, C. Leung, T.R. Oxland,H.A. McKayStrength indices from pQCT imaging predict up to 85% of variance in bone failure properties at tibial epiphysis and diaphysis ........................................................................................ 401
G. Mayot, D. Breuillé, A-R. Jarret, C. Obled, I. PapetSystemic low-grade inflammation does not decrease skeletal muscle mass and protein synthesis in old rats .......................... 410
Index of Volume 8 ........................................................................ 418