VOL II , 2016-2017gnkgei.ac.in/pharmacy/wp-content/uploads/2016/06/e... · HOMEOPATHIC MEDICINE:...

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VOL II , 2016-2017

Transcript of VOL II , 2016-2017gnkgei.ac.in/pharmacy/wp-content/uploads/2016/06/e... · HOMEOPATHIC MEDICINE:...

  • VOL II , 2016-2017

  • Work hard in silence let success make the noise.

    Scientific and Research Section

    Curricular & Extra - Curricular Activities

    Poem

    Joke

    Pharma Digest

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  • VISION

    To develop as centre of excellence in pharmacy education

    where leaders in pharmacy Practice, teaching and public sector

    are nurtured and developed to serve for mankind.

    MISSION

    To impart profound pharmaceutical knowledge through

    quality research and training programs to cater the needs of

    healthcare sector and diverse communities thereby facilitating the

    development of socially responsible pharmacists.

    PROGRAMME EDUCATIONAL OBJECTIVES

    Educating Pharmacy students through innovative, practical oriented teaching methods to

    facilitate their overall professional development.

    Promoting students and faculty members for conducting basic and applied research

    and scholarly activities for their overall development.

    Foster an entrepreneurial spirit amalgamated with team work, leadership qualities

    and multidisciplinary approach.

    Contributing to society through healthcare awareness programs.

    To inculcate in students professional and ethical attitude, effective communication

    skill and awareness to current trends by engaging in lifelong learning to enhance skills

    within and across disciplines to compete globally.

    EDITORIAL BOARD:

    Editor: Mr. Deepak Pradhan

    Joint Editor: Mr. Ajay Kumar (B. Pharmacy 4th

    Year)

    Mr. Amandeep Singh (B. Pharmacy 3rd

    Year)

    Ms. Vanisha Singhal (B. Pharmacy 2nd

    Year)

    Mr. Shashwat Sharma (B. Pharmacy 1st Year)

    Members: Dr. Sanjeev Kumar

    Mrs. Prativa Biswasroy

    Mrs. Priyanka Kriplani

    Mrs. Bhawana Chopra

    Mr. Rohit Kamboj

  • Inside the Issue.........................................................

    Scientific and Research Section

    Slogan Graduate Pharmacy Aptitude Test (GPAT) Curricular & Extra - Curricular Activities

    Pharma Digest

    Quotation by the Scientist Poem

    Joke

  • Don’t educate your children to be rich. Educate them to be happy. So when they grow up

    they know the value of thing not price. Page 1

    GREEN TEA AND POSSIBLE INTERACTIONS

    Amandeep Singh

    3rd

    year,B.Pharmacy

    Tea is the second most consumed beverage after water. Tea is traditional

    beverage originally from china is the oldest, most popular, non - alcoholic,

    caffeine containing beverage in the world. Green tea is made from the

    leaves of the plant Camellia sinensis. This widely drunk across Asia. The

    rates of cancer are much lower in Asia than other parts of the world. There

    is several major cancer fighting substances in green tea. Some of these

    include epigallocatechin-3-galatre, epictechin, epicatechin-3-sulfate, epigallocatechin. Along

    with these there are also some possible interactions with green tea. If you are being treated with

    these medications you should not drink green tea or green tea extracts. Green tea may inhibit the

    action of the adenosine, a medication given in the hospital for an irregular heart rhythm. Green

    tea may increase the effectiveness of beta-lactum antibiotics by reducing bacterial resistance to

    treatment. People who take warfarin, a blood thinning medication, should not drink green tea

    since green tea contains vitamin k, it can make warfarin ineffective. Meanwhile you should not

    mix green tea and aspirin because the both prevent platelets from clotting, using the two may

    increase your risk of bleeding. Both green and black tea extracts stimulating a gene in prostate

    cancer cells that may cause them to less sensitive to chemotherapy drugs. When taken together

    with ephedrine, green tea may cause agitation, tremors, insomnia, and weight loss. Green may

    cause severe increase in blood pressure when taken together with MAOIs, which are used to treat

    depression.

    WHY SHOULD WE STUDY ZOOPHARMACOGNOSY

    Tanishkochar

    1styear,B.Pharmacy

    May be even more important than the medicinal potential, the understanding of animal self-

    medication can help us safeguard our food supply. Good, for the most part, is no longer formed,

    but mass-produced. But nature does not function as such. Nature functions as a web of diverse

    interlinking overlapping & complex relationships, which do not run on a linear plane as found on

    a factory floor. Zoopharmacognosy principles could save the farming industry billions of dollars.

    When animals are given the option of self medicate, farmers will no longer have to give

    antibiotics to all their animals, including the healthy ones, as they do now. Swine flu has become

    endemic all over the world and we understand now how unhealthy animals can all too quickly

    translate into unhealthy humans. There are many zoonotic diseases that may have been

    prevented, had we understand more fully the implication of animal self-medication.

  • “Ego” is the only requirement to destroy any relationship….So, be a bigger person skip the “E”

    and let it “Go” Page3

    MIGRAINE AND HERBAL REMEDIES

    Kamaljeet Singh

    3rd year B.Pharmacy

    Migraines are intense, sometimes debilitating headaches. The most common types of migraine

    are those with aura (classical migraines) and those without aura (common migraines).Migraines

    can begin in childhood or may not occur until early adulthood. Women are three times more

    likely than men to have migraines. Family history is one of the most common risk factors for

    having migraines.

    Causes: Factors that may trigger a migraine include:brightlights, severe heat or other extremes in

    weather, changes in barometric pressure, hormonal changes, such as estrogen fluctuations during

    menstruation, pregnancy, menopause for women, drinking alcohol or caffeinated drinks. Foods

    such as aged cheese, processed foods; consuming food additives, such as aspartame (an artificial

    sugar) or monosodium glutamate (MSG),eating foods that have the additive tyramine, which is

    found in soy products, fava beans, hard sausages, smoked fish, and Chianti wine. Excess stress,

    loud sounds, skipping meals, loss of sleep, taking certain medicines, such as oral contraceptives

    or nitroglycerin.

    Symptoms: Food cravings, depression, fatigue or low energy, frequent yawning.

    Herbes used in migrane: Passion flower used as a calming herb for such conditions as anxiety

    and insomnia, passionflower can also be helpful in easing headaches for people of a certain

    constitution. “As the name suggests, passionflower is good for people who get easily worked up

    about life,” says Lawton. “For people who are very passionate, who get easily angered, this herb

    calms the nervous system and makes them less likely to hold onto the headache.”Black cohosh is

    native of North American, which has a history of being used for rheumatism, can be extremely

    effective in treating headaches associated with what’s known as “black cloud depression.”

    Because the herb has estrogen effects, it is better for women, but men can take it for short

    periods as well.White willow bark, like other headache herbal remedies, relieves pain. But as an

    analgesic, it masks the pain rather than addressing the underlying cause of the headache the way

    other herbs do.

  • “APOLOGISING” does not always mean that you are wrong and the other person is right. It just

    means that you value your relationship more than your ego. Page 4

    MAIN SECRETS THAT ONLY PHARMACIST KNEW

    Jagmeet

    1st year, B.Pharmacy

    Nobody knows more about medications than Pharmacists do-not

    doctors, not nurses and not anyone. Someone says that," those with right

    to prescribe know far less about drug therapies than pharmacists, and

    consumers need to make use of that knowledge. Mornings are the best

    time to fill prescription; Like doctors, pharmacists especially those at

    mom-and-pop shops, who don't have quotes to meet, are less likely to

    make you wait for first thing in the morning. As Martin Ochalek, a

    pharmacist in Miami, puts it, "Once the doctors calls start coming, it

    slows down everything." The exception independent pharmacies. "Any time of day is a good time

    to call in a prescription since they need the business", says Joey Jimenez, a former pharmacy tech

    who specializes in compound drugs at total pharmacy supply. Another timesaving tip: call before

    you go to confirm your prescription is ready for pick up. If it takes longer than 15 minutes, be

    patient; Greeting the wrong prescription can have serious consequences, which is why it pays to be

    patient. Time pressures can contribute to medication errors. The pharmacist does for more than

    count pills and place them into a bottle pharmacists are reviewing allergies, drug interactions,

    dosing and much more to be sure you get a medication that will be safe and effective for you.

    Doctor's handwriting really is that bad; that it can lead to mistakes- which are why pharmacists need

    to be extra vigilant when filling prescriptions. While a call to the doctor can clear up all issues, it's

    an extra step. Don’t wait until you’re out of medicine to order refills; doctors are busy people and

    they’re the ones who hold the key to you getting a refill for your medication which is why it’s

    important to give your pharmacist a few days to get an hold of them. Doctors don’t always call back

    promptly, and it’s not automatic that you get a refill the same day. Let the pharmacist knows when

    you have 5 or 6 pills left. This is especially true for maintenance drugs like blood pressure medicine

    missing a day or waiting extensive periods of time between dosages can have harmful effects.Don’t

    use the pharmacy checkout if you’re not picking up a prescription; We’ve all been there before, the

    checkout line snakes into the aisles and you want to buy are a few toiletries. But resist the

    temptation to pay at the pharmacy; while pharmacists are happy to help, it distracts them from the

    important work they’re doing, which can lead to unintentional errors.

  • “RELATIONSHIP” never dies a natural death…They are killed by Ego, Attitude and

    Ignorance. Page 5

    OBESITY AND ITS PHARMACOTHERAPY

    Sugreev

    3rd

    year,B.Pharmacy

    Obesity is a global public health crisis. It is defined as excessive

    accumulation of the body fat that may impair health. Obesity to be

    related to increased risks of coronary heart disease, hypertension, non-

    insulin dependent diabetes mellitus and certain types of cancer. The

    genetic makeup plays a significant role in the chances of becoming

    obese. Many synthetic drug therapies are available for the treatment of

    obesity, but they are not devoid of side effects and not recommended for long term therapy. A

    combination of amphetamine analogs, fenfluramine and phentermine, fen-phen’s effectiveness

    helped to achieve extensive popularity in 1990s.Unfortunately it also caused pulmonary

    hypertension and valvular heart disease. Phentermine and topiramate combination is also used in

    management of obesity. Obesity treatments may include physical activity, changes in eating

    behavior, pharmacotherapy, weight reducing medicinal plants, accupuncture etc. Anti-obesity

    drugs may be taken to reduce appetite or inhibit for together with a suitable diet. There is an

    urgent need of exploring all the available options to address the menace of this metabolic

    disorder.

    ANTICANCER DRUGS

    Jaspreet Singh

    3rd

    year, B.Pharmacy

    Drugs used for the treatment of cancer known as cancer chemotherapy. A cancer is defined as

    uncontrolled division of cells leading to a tumor formation. Cancer is the abnormal growth of

    cells in our bodies that can lead to death. Several drugs used in cancer are cytotoxic drugs,

    hormones and enzymes like L-Asparaginase. Plant derived agents are being used for the

    treatment of cancer. The causes of cancer are smoking, dietary imbalance, hormones and their

    chronic infection leading to chronic inflammation. The anticancer activity is the effect of natural

    and synthetic or biological and chemical agents to reverse, suppress or prevent carcinogenic

    progression. Plant derived compounds have an important source of several clinically useful

    anticancer agents including taxol, vinblastine, vincristine, the camptothecin derivatives topotecan

    and etoposide.

  • The true purpose of Education is to make minds, not careers. Page 6

    HOMEOPATHIC MEDICINE: REALITY OR A PLACEBO

    Shashwat Sharma

    1st year, B.Pharmacy

    Homeopathy is the third most commonly used system of healing in the world and has been

    practiced for more than two centuries, mainly because of its easy availability, low cost,

    negligible side effects. But its acceptability is still on the borderline of reality and placebo.

    Mainstream scientists treat it as an outcast, blaming the curing power as nothing but placebo

    effect, even there is ample evidence of millions of people having been cured by homeopathy.

    Some very interesting observations about this medicine system are the following:

    a) Contrary to allopathic medicines, homeopathic medicines are said to be more potent at

    higher dilutions.

    b) A large number of homeopathy practitioners have their basic degree in allopathy, and

    c) Even the most sceptic ones use homeopathy as regular basis.

    Then why this step-motherly attitude to homeopathy? Perhaps the reason behind this is lack of

    adequate research to explain how homeopathy really works. Also it is very subjective-the same

    medicine for particular ailment may not work for two different persons; the personal history

    matters a lot. However, the fact that these medicines are said to be active even at extreme

    dilutions has drawn the specticism and curiosity of the scientists leading t the popular brief that

    perhaps these medicines have only a placebo effect. One typical operation used in making of

    homeopathic medicines is repeated shaking or „succession‟ of the solution of the drug in alcohol.

    It has been found that such repeatedly shaken extremely dilute solutions or “very low molarity

    repetitive successed diluted liquid” (VLMRSDL) of which a homeopathic medicine is an

    example, has its properties modified significantly from the original liquid.We decided to study

    how these drugs penetrate the membrane and whether there is any correlation of this penetration

    with the potency of homeopathic drug. For this study we choose two homeopathic drugs such as

    Aconitum napelles, Cuprum metallicum. Thus from the above observations it can be concluded

    that homeopathic medicines are indeed more potent at higher dilutions because of the drug

    dilutions because of the drug particles attaining the size in nano range, which then facilitates

    their penetration through the cell membrane thereby enhancing the desired effect.

  • Education is learning what you didn’t even know you didn’t know. Page 7

    ZIKA VIRUS

    Tarundeep Singh

    3rd

    year,B.Pharmacy

    Zika virus is an emerging mosquito-borne virus that was first

    identified in Uganda in 1947 in rhesus monkeys through a

    monitoring network of sylvatic yellow fever. It was

    subsequently identified in humans in 1952 in Uganda and the

    United Republic of Tanzania. Outbreaks of Zika virus disease

    have been recorded in Africa, the Americas, Asia and the Pacific.

    Virus classification

    Genre: Flavivirus Vector: Aedes mosquitoes (which usually bite during the morning and late

    afternoon/evening hours) Reservoir: Unknown

    Symptoms;can have no symptoms but people may experience, pain areas, in the back of, eyes,

    joints or muscles,wholebody,fatique,fever,chillsalsocommon,eyeredness,headache,skin rash.

    Transmission; Zika virus is transmitted to people through the bite of an infected mosquito from

    the Aedes genus, mainly Aedes aegypti in tropical regions. This is the same mosquito that

    transmits dengue, chikungunya and yellow fever.

    Diagnosis; Infection with Zika virus may be suspected based on symptoms and recent history

    (e.g. residence or travel to an area where Zika virus is known to be present). Zika virus diagnosis

    can only be confirmed by laboratory testing for the presence of Zika virus RNA in the blood or

    other body fluids, such as urine or saliva.

    Prevention; Mosquitoes and their breeding sites pose a significant risk factor for Zika virus

    infection. Prevention and control relies on reducing mosquitoes through source reduction

    (removal and modification of breeding sites) and reducing contact between mosquitoes and

    people.Repellents should contain DEET (N, N-diethyl-3-methylbenzamide), IR3535 (3-[N-

    acetyl-N-butyl]-aminopropionic acid ethyl ester) or icaridin (1-piperidinecarboxylic acid, 2-(2-

    hydroxyethyl)-1-methylpropylester).

    Treatment; Zika virus disease is usually relatively mild and requires no specific treatment.

    People sick with Zika virus should get plenty of rest, drink enough fluids, and treat pain andfever

    with common medicines. If symptoms worsen, they should seek medical care and advice. There

    is currently no vaccine available.

  • “Great minds discuss ideas. Average minds discuss events. Small minds discuss people”. Page 8

    SCREENING PREVENTS 70% OF CERVICAL CANCER DEATH

    Shikha Kamboj

    1st

    year, B.Pharmacy

    Screening for cervical cancer prevents 70% of deaths from the diseases, but this figure could be

    as high as 83% if all eligible women had regular smear tests, according to new research by

    cancer research UK. Around 800 women in England die from cervical cancer each year. The CR

    UK study concludes that, without screening, an additional 1,827 more women would die from

    the disease. However if all women aged from 25 to 64 were screened regularly. They also found

    that the biggest impact of screening is among women aged between 50-64, where there would be

    five times more deaths from the disease, & that there would be more than twice the no. of

    cervical cancers diagnosed if there were no screening programme. Thousands of women in the

    UK are alive & healthy today thanks to cervical screening. The programme already prevents

    thousands of cancers each year & as it continues to improve by testing all samples for the human

    papilloma virus (HPV) even more women are likely to avoid this disease.

    SWINE FLUE Souravsharma

    1styear,B.Pharmacy

    Swine influenza, also called pig influenza, swine flu, hog flue and pig flue is an infection caused

    by the any one of several types of swine influenza viruses. The swine flu was initially seen in the

    humans in Mexico in 2009 where the stand of particular virus was a marriage of three types of

    stands. Around the mid of 20th

    century, identification of influenza subtypes become possible,

    allowing accurate diagnosis of transmission to humans. Causes: Direct transmission of a swine

    flu virus from the pigs to humans is occasionally possible (zoonotic swine flu). According to the

    center for disease control and prevention, in humans the symptoms of the 2009 “swine flu” virus

    are similar to those of influenza and of influenza like illness in general.Symptoms of swine flu in

    human: Body ache, Cough, Sore throat, Fever, VomitingPreventionof swine flu: Wash your

    hands with soap regularly, Get plenty of sleep, Eat a well-balanced diet, Drink plenty of liquids.

    Treatment for swine flu: There are some drugs around that can effectively treat the swine flu

    infections in human. Adamantanes (amantadine and remantadine), Inhibitor of influenza

    neuraminidase.

  • Speak only when you feel that your words are better than your silence. Page 9

    ROBOTIC SURGERY Preetpal

    1st year, B. Pharmacy

    Robotic surgery, computer-assisted surgery, and robotically

    assisted surgery are terms for technological developments to use

    robotic systems to aid in surgical procedures.Robotically-

    assisted surgery was developed to overcome the limitations of

    pre-existing minimally invasive surgical procedures and to

    enhance the capabilities of surgeons performing open surgery. In

    case of robotically-assisted minimally invasive surgery, instead of directly moving the

    instruments, the surgeon uses of the two methods to control the instruments; either a direct

    telemanipulator or through computer control. A telemanipulator is a remote manipulator that

    allows the surgeon to perform the normal movements associated with the surgery whilst the

    robotic arms carry out these movements using end effectors and manipulators to perform the

    actual surgery on the patient. In computer controlled systems the surgeon uses a computer to

    control the robotic arms and its end effectors, though these systems can also still use

    telemanipulators for their input. One advantage of using the computerized method is that surgeon

    does not have to be present, but can be anywhere in the world, leading to the possibility of the

    remote surgery.The main objective of such smart instruments is to reduce or eliminate the tissue

    trauma traditionally associated with open surgery without requiring more than a few minutes

    training on the part of the surgeons.

    GOVERNMENT BANNED NIMESULIDE OVER ADVERSE EFFECTS ON

    LIVER.

    Shubham Tyagi

    1st year, B.Pharmacy

    “Nimesulide causes liver failure”.

    The government has banned the Paediatric use of the common fever &

    pain drug Nimesulide. For its adverse effects on the liver, in a much-

    delayed move. The decision was taken by the union health ministry after

    experts on the drug Technical Advisory Board recommended banning

    the drug with five others. The ministry decided Nimesulide’s Paediatric formulation along with

    cisapride, Phenylpropanolamine, human placenta extract & sibutramine& R-sibutramine.

    Nimesulide causes liver failure, while cisapride, an anti-obesity drugs, is associated with

    increased risks of Heart attacks.

  • Nothing is permanent. Don’t stress yourself too much because no matter how bad the situation

    is…it will change. Page 10

    IRRITABLE BOWEL SYNDROME

    Anshulmittal

    3rd year,B.Pharmacy

    A widespread condition involving recurrent abdominal pain

    and diarrhoea or constipation, often associated with stress,

    depression, anxiety, or previous intestinal infection.

    Symptoms

    Symptoms include abdominal pain or discomfort and

    changes in bowel habit (constipation, diarrhoea, or both), as

    well as bloating. While some people have intermittent symptoms, for others the condition

    difficult to treat.There are no investigations or tests that can confirm the presence of IBS, so it

    should be considered in people who have had any of the following symptoms for six months or

    more. Abdominal pain or discomfort, bloating, change in bowel habit.

    Causes of IBS

    The cause of IBS and the pathophysiology of the symptoms are unknown but it is believed that

    the normal digestive process is somehow altered and that there may be increased sensitivity of

    the GI tract. While other causes such as gastroenteritis, antibiotics, inflammation and family

    history have been proposed, there is no evidence to support any of them, but a number (stress,

    antibiotics and gastroenteritis) are known to aggravate the condition.

    Treatment

    Treatment of IBS involves addressing the most predominant symptoms, which may involve

    using a combination of drugs to keep those symptoms under control.Stomach pain caused by

    muscle spasms, for example, can be treated with antispasmodics such as peppermint oil, alverine

    citrate or mebeverine. These act on the intestinal smooth muscle, causing it to relax. Other

    muscle relaxants (e.g. hyoscine) are likely to cause antimuscarinic side-effects so are better used

    as a second-line option. Laxatives, such as ispaghula, will help relieve constipation associated

    with IBS, and are preferable to lactulose, which may exacerbate bloating. For those unable to

    take bulk-forming laxatives, alternatives include stimulant preparations like senna, or osmotic

    laxatives containing macro gel.

  • Sitting alone and enjoying your own company is better than being surrounded by fake people.

    Page 11

    HUNTINGTON'S DISEASE Arpit Prajapati

    3rd

    year,B.Pharmacy

    Huntington's disease is an inherited disease that causes the

    progressive breakdown (degeneration) of nerve cells in the

    brain. Huntington's disease has a broad impact on a person's

    functional abilities and usually results in movement, thinking

    (cognitive) and psychiatric disorders. Most people with

    Huntington's disease develop signs and symptoms in their 30s or 40s, but the onset of disease

    may be earlier or later in life. When disease onset begins before age 20, the condition is called

    juvenile Huntington's disease. Huntington's disease usually causes movement, cognitive and

    psychiatric disorders with a wide spectrum of signs and symptoms.Loss of previously learned

    academic or physical skills.Contracted and rigid muscles that affect gait (especially in young

    children). Huntington's disease is caused by an inherited defect in a single gene. Huntington's

    disease is an autosomal dominant disorder, which means that a person needs only one copy of

    the defective gene to develop the disorder. No treatments can alter the course of Huntington's

    disease.

    TERMINALIA CHEBULA Gurdeep Singh

    3rd

    year, B.Pharmacy

    Terminaliachebula is a medicinal plant widely distributed

    throughout India, Burma and Shrilanka. Many Indian plant has been

    used from immemorial to treat varies diseases and infection in

    traditional medicine system. Terminalia chebula is called the king

    of the medicine in Tibet and is always listen at the top of the list in

    Ayurveda medicine. In Terminalia chebula, 33% of the total phytoconstituents are hydrolysable

    tannins (which may vary from 20-50%) and are responsible for pharmacological activity.

    Aqueous extract of T. chebula has been reported to show antifungal activity against a number of

    dermatophytes. The extract of fruits of T. chebula showed inhibitory effects on human

    immunodeficiency virus-1 reverse transcriptase-III. Terminalia chebula (haritaki) is one of the

    most important medicinal plants used in medicines of ayurveda, siddha, unani and homeopathy

    because of having a number of pharmacological properties. Therefore, there is an urgent need to

    investigate the biological activity of its phytoconstituents for development of an effective, safe

    and cheap herbal drug.

  • CHEATING: on a good person is like throwing away a diamond and picking up a rock. Page 12

    THE SALUTABLE INVENTION – STEM CELLS

    Vanisha Singhal

    2nd

    year ,B.Pharmacy

    When I was a small kid, I used to wonder how my hair grew when I got them trimmed. To me, it

    seemed a magic which no one could see. While reading science magazines, the articles on tissue

    cultures used to captivate my attention. I wondered how a single tissue could transmute into a big

    plant. When I further read about hydra and planaria and their capacity to regenerate lost body

    parts, my curiosity to explore further grew infinitely. It was wondrous for me how starfish and

    lizard could revive their body parts.

    Then a thought struck my mind-Wouldn’t it be marvellous if human internal organs too showed

    the same characteristics. When we get wounded, within a few days, our cells repair to form a

    new layer of skin but how piteous we feel when the doctor tells us that our liver or any other

    internal organ is damaged?? But the good news is that now, there is no need to worry about such

    things!! With the increasing advancement in bio-technology, great significant developments have

    taken place in the field of stem cell research especially in past two years. It has considerably

    contributed to expand human frontiers of science. It has paved a new path for curing some

    hazardous diseases which were once considered a myth.The development in stem cell research

    has touched great heights. However, the idea of this research is very much primitive. The time

    when microscopes were invented and cell therapy was developed, scientists became well aware

    of complex cells that constitute the human body. The coining of the term ‘stem cell’ can be

    traced back to late 1800’s, however not much knowledge about them was possessed by any of

    the biologists till then. In early 1900’s more information about bone marrow cells came forward

    which eventually led to transplant of bone marrow and adult stem cells for treating Leukemia

    and other diseases of blood. The human stem cell research took off its journey in late 20th

    century with enormous advancement in technology.

  • Two things define you…your patience when you have nothing and your attitude when you have

    everything. Page 13

    Soon after, the scientists could use human embryonic

    stem cell linesto entirely establish the striking

    capabilities of stem cells, provoking new hopes of their

    possible use to renew cells for vast range of tissues and

    organs. Right from the beginning, the facts revealed and

    discovered in stem cell research have left the scientists

    even spellbound. Our grandparents could never imagine

    even that so many ailments could be cured using our own cells. In their times, it was beyond

    their grasp to heal such ailments but the stem research has paved new paths.

    USA scientists proclaimed that if sponges are soaked in stem cells and applied to the mouth of

    patients with open wounds in the oral cavity, the bones grew more effectively. In the area where

    damaged teeth should have been, sponges were inserted and it was remarked that the tissue

    regenerated faster than possible with bone grafts. Moreover, the bone tissue formed possessed

    capabilities to support the implantation of false teeth. This gives new directions for new

    treatment, addressing a wide variety of condition affecting the teeth, gums and underlying bone.

    Today, it has become a tedious job for doctor to find transplant donors but stem cells are acting

    like magic tools for them. These days, HIV is a problem which can make any one its victim and

    being a global problem, scientists are toiling hard to find way outs and new treatment to cure

    HIV. But it is due to the sake of stem cells that new hopes are arising among doctors and patients

    for curing this hazardous disease.

    In today’s era, there are innumerable patients of diabetes. The disease is troubling a lot of people.

    Wouldn’t it be great if some miracle appears to reduce the effect of this disease? Stem cells have

    the potential to create that miracle!! Researchers have proclaimed that it may be possible to

    generate specialized cells capable of generating insulin. These cells will be transplanted into

    diabetics and remove the need of insulin injection.The achievements in the field of stem cell

    research do not end here. They have even been used to treat heart diseases. The research

    conducted laboratory animals like mice has shown that transplantation of stem cell from non

    heart tissues into a damaged heart, healthy heart muscle cells were able to grow.

    Although it is not possible to live forever or gain eternity but developments in stem cells have

    paved new paths to increase life expectancy and thereby benefitting the entire mankind.

  • When our nails grow long, we cut nails not fingers, similarly when misunderstanding grows up

    cut your ego not relationship. Page 1

  • A satisfied life is better than a successful life, because our success is measured by others but our

    satisfaction is measured by our own Mind Heart and Soul. Page 1

  • GOD is like oxygen, you can’t see him but you can’t live without him. Page 16

    PARENTS

    Vanisha Singhal

    2nd

    year ,B.Pharmacy

    You are both special in every way,

    Encouraging me more & more each passing day

    You both are the reason why I’m so strong

    With you two guides I know nothing can go wrong

    You have both helped me through many trials & tribulations

    You have made things better in every situation

    Thank you both, for always being there

    And showing me that you truly care

    Words could never explain how I feel about you

    But I hope you know that I truly respect you

    भाई-बहन

    बाई-फहनकेप्मायकाफॊधनहोताहैफड़ाअनूठा,

    चाहेराखभुसीफतेंआएॉ, मेरयश्ताकबीनटूटा,

    फहनभाॉकीतयहबाईऩयभभतारुटातीहै|

    बाईबीहयकष्टसहकयअऩनीफहनऩयजानरुटाताहै |

    कबीभीठीनोकझोंकहोतीहैदोनोंकेफीच,

    तोकबीदोनोंएक-दसूयेकीताकतफनजातेहैं|

    कबीछोटी-छोटीचीजोंकेलरएरड़तेथेजो,

    एक-दसूयेकेलरएफड़ी-फड़ीकुफााननमाॉदेजातेहैंवो,

    याखीऔयबाईदजूइसरयश्तेकोफपयसॊवायजातेहैं |

    ददरकीनजदीफकमोंकेआगेदरूयमोंकोलभटाजातेहैं |

    बाई-फहनदोनोंबफनकहेएक-दसूयेकीफातसभझजातेहैं|

    फहनकेहाथोंकेफनेऩकवान, हभेशाबाईकोरुबातेहैं|

    हयगुजयतेददनकेसाथइसरयश्तेकीअहलभमतफढ़तीजातीहै|

    फचऩनकीखट्टी-भीठीमादें, इसरयश्तेभेंऔयलभठासघोरजातीहै|

  • Successful persons carry two things at their face: “SMILE And SILENCE”. Page 17

  • Work hard in silence…..let success make the noise Page 18

  • Education is the most powerful weapon for changing the world. Page 20

    Sumanyu

    YatinNarang

    Yatin Bhatia

    1st year, B. Pharmacy

    1. Sun Pharma entered into an agreement to acquire InSite Vision: Sun pharmaceutical

    industries entered into a deal to acquire US-based InSight vision Inc. for about 300 crores.

    2. National Centre for R&D in Bulk Drugs to be set up in NIPER Hyderabad: union

    ministry in of chemicals and fertilizers decided on 14 July 2014 to set up National Centre

    for Research and Development in Bulk Drugs (NCRDBD).

    3. Sun Pharma announced to acquire Ranbaxy Laboratories for 3.2 billion dollars: Sun

    Pharma acquires Ranbaxy for 3.2 billion dollars.

    4. SC asked Centre to respond on the Drug Pricing Policy under NPP policy: SC agreed

    to examine the new national Pharmaceutical pricing policy framed by the government for

    fixing prices of essential medicines.

    5. Foreign Investment Promotion Board Approved 7 Pharma FDI proposals:Foreign

    Investment Promotion Board approved seven foreign direct investments (FDI) proposals

    for investment in Indian pharmaceutical companies.

    6. Sun Pharmaceuticals Industries got approval from USFDA for DepoTestosterone

    injection: Sun pharmaceuticals announced that got the final approval for USFDA for

    generic testosterone cypionate injection.

    7. Indian asked for more market access from Japan during the visit of Anand Sharma:

    Anand Sharma demanded for more market access for Indian exporters in sectors like

    agriculture, marine and pharmaceutical products during his visit in japan.

    8. 22 Foreign Direct Investment (FDI) proposals worth Rs. 586.137 crores approved by

    the government. Economy current affairs, Union Government approved 22 FDI

    proposals, amounting to Rs. 586.137 crores following recommendations made by the

    Foreign Investment Promotion Board (FIPB).

  • Education is the most powerful weapon for changing the world. Page 20

    9. Changes in the Foreign Direct Investment Regime for the pharmaceuticals sectors

    notified: Economy Current Affairs changes the FDI Regime for the pharmaceuticals

    sectors was notified by the department of industrial policy.

    10. Union Commerce and Industry Ministry announced a Rs.900 crore package for

    exporters:commerce and Industry Ministry announced a Rs. 900 crore package for

    exporters to support exporters against slowdown in US and Europe.

    11. Drug maker Lupin entered into license agreement with drug makerAbbott

    laboratories: Lupin entered into a license agreement with Abbott and industries SA on 8

    patients on cholesterol lowering drugs.

    12. Genpact acquires SMS:Genpact announced that they had acquired symphony marketing

    solutions with a view to expand its retail pharmaceutical growth across the world.

    13. Judgment in the favor of Sun Pharmaceuticals: Sun pharma got a favourable ruling

    from US district court of southern district of New York and can acquire Israeli drug Taro.

    14. Lupin completed the acquisition of GAVIS Pharma: both the companies will have the

    portfolio of 120 in-market products, 185 cumulative filings pending approvals and a deep

    pipeline of products under development for the US.

    15. CCEA approved two FIIs proposals in pharmaceutical companies Aurobindo and

    Glenmark: The foreign investments worth 4187 cro res will help the companies to

    expand their operation and research and developments facilities.

    16. Lupin to acquire additional 40% stake in SOUTH AFRICA’s Pharma dynamics:

    with this acquisition, lupin has 100% stake in the company pharma dynamics will become

    a wholly-owned subsidiary of lupin.

    17. RPG life lost the battle for domain name rpglife.com: RPG life sciences, a pharma

    company from India, lost the battle for domain name rpglife.com

    18. Only 5 out of 25 deaths caused by Clinical Trials compensated as per DCGI Records:

    Drug controller general of India (DCGI) records pointed out 25 people died in clinical

    trials carried out by nine pharmaceutical companies in India.

    19. Lupin settled dispute over: Drug firm Lupin settled ongoing litigation over lunesta

    tablets with Japan based Dainippon SumitomaPharma.

    20. Reorganization of Alembic: Pharma legends Albemic are believed to be reorganized till

    the end of this year in order to increase their global sales.