VITILIGO

Anatomy of skin

BACK TO TOPPhysiology of MelanocyteLocated at the epidermis of the skin specifically at stratum basalisAlso exists in the uvea, inner ear, meninges, bones and heartFuntion as pigmention of the skin colourUndergo process melanogenesis to produce melanin

BACK TO TOPEtiologyAutoimmuneGenetics/hereditaryNeural theoryDisturbance in oxidant-antioxidant system (release of free radicals)Cellular immune mechanismsBACK TO TOPSIGNS and symptomsMilky-white maculesWell bordered lesionsInitial lesion located at the face, arms, forearms and feetBACK TO TOPCLASSIFICATIONSLOCALIZED :FokalSegmentalMukosal

GEENRALISED : AkrofasialVulgarisCampuranBACK TO TOPDIFFERENTIAL DIAGNOSISPiebaldismSindrom WardenburgSindrom woolfTinea VesicolorPitiriasis AlbaNervus depigmentousus (Segmental)Lesi tunggal atau sedikitBACK TO TOPAutoimmune

Neural Theory

COMPLICATIONSSkin cancerHipoacusisUveitisBACK TO TOPPathophysiology Genetics