Aquamedical contractresearch facility

Technical descripTionVESO Vikan is a state-of-the-art non-recirculation trialunit lab with advanced registration and surveillancesystems. e research facility consists of a wet lab with separate isolates and holding tanks from 8 to 7500 liters. e tank design can be customized toaccommodate research needs, including individual lightregimes, salinity and temperature. Tank numbers in

use varies from 200 to 1000, depending on the natureof the trials. e research facility has two fresh watersources and sea water is drawn from 60 meters depthoutside the facility. Incoming water is filtered and UV-treated prior to admittance to the test area. esalinity of the ord water is ~33 ‰. Effluent water isdisinfected with chlorine and ozone.

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is an aquatic research facility for contract challenge trials forthe pharmaceutical-, feed- and breeding industries, research institutionsand government bodies. VESO Vikan offers standardized challengemodels for Atlantic salmon, rainbow trout, seabass and Atlantic cod. Pathogens include viruses, bacteria and parasites. VESO Vikan offerslong-term vaccine studies (duration of protection) and field trialsconducted under commercial farming conditions. We also focus on safetyaspects of veterinary medical products.

As a contract research facility, VESO Vikan represents an independentpartner, ensuring full confidentiality and customer dedication. VESO Vikan focuses on trial quality systems and strives to maintain the highest ethical profile in all our activities. Our aim is to make the VESO trademark synonymous with uncompromising quality and reliability in fish health research.

V I K A N

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challenge FaciliTychallenge experiments are designed to evaluate theefficacy of vaccines, effects of feeding or genetic resistance profiles against infectious agents. VESOVikan’s R&D focus is to develop and maintain reliableand clinically relevant challenge models for pathogensaffecting global aquaculture, especially Salmonids. VESOVikan’s highly qualified and experienced staff works in

close collaboration with research institutions and theaquaculture industry. We subcontract expertise andservices on behalf of our customers when necessary to ensure full width documentation of test products and compliance with formal test requirements. We are happyto develop new models and standards in collaborationwith our clients.

FISh InFEcTIOUS agEnT DISEaSE

atlantic Aeromonas salmonicida Furunculosissalmon Vibrio anguillarum o1/o2a Vibriosis

Vibrio ordalii VibriosisMoritella viscosa Winter ulcersPiscirickettsia salmonis salmon rickettsial syndrome (srs)piscine reovirus (prV) heart and skeletal muscle inflammation (hsMi)piscine myocarditis virus (pMcV) cardiomyopathy syndrome (cMs)infectious pancreatic necrosis virus (ipnV) infectious pancreatic necrosis (ipn)infectious salmon anemia virus (isaV) infectious salmon anemia (isa)salmon pancreas disease virus (spdV) pancreas disease (pd)Lepeophtheirus salmonis sea lice infection

rainbow Aeromonas salmonicida Furunculosistrout Vibrio anguillarum o1/o2a Vibriosis

infectious pancreatic necrosis virus (ipnV) infectious pancreatic necrosis (ipn)

atlantic Vibrio anguillarum o1/o2a/o2b Vibriosiscod Francisella sp. Francisellosis

sea bass Vibrio anguillarum VibriosisPhotobacterium damselae pasteurellosis

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FirsT Floor

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haTcherySalmon for experimental trials in the laboratory and field are produced at VESO Vikan’s hatchery. Production of ourown salmon ensures quality in every stepfrom egg to seaworthy smolts.

e hatchery produces atlantic salmon(15–30 grams) all year round, includingsalmon genetically bred for high or lowresistance against disease. Our fish arescreened and certified pathogen free before being used in trials.

Field TrialsVESO Vikan holds two salmon farminglicenses for R&D. e licenses enable trial conduct under commercial farmingconditions throughout the salmon lifecycle from hatching to harvest. Fish thatare included in field trials are produced at VESO Vikan hatchery. e key application for this composite trial system is to enable evaluation of efficacyand side effects of vaccines in a real-lifeenvironment and to facilitate clinicalvalidation of our laboratory challengemodels. VESO Vikan has considerableexperience in administering field trials and provides administrativeand scientific services for full-scale testing of vaccines andpharmaceuticals. Trials are routinely conductedaccording to gcP(good clinicalPractice).

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sTaFFe scientific staff at

VESO Vikan comprisesfish health biologists,

veterinarians and universitygraduates (Msc or PhD). e

technical staff is educated inaquaculture. all employees aretrained to conduct trials accordingto the principles of gLP. good Laboratory Practice.

QualiTy assuranceVESO Vikan is certified accordingto gLP (good Laboratory Practice)by e norwegian accreditationagency and holds a manufacturinglicense for medicinal products granted by the norwegian Medicines agencyaccording to gMP (good ManufacturingPractice) requirements.

Trials in the laboratory and field can be performed according to gcP (good clinicalPractice). gcP ensures international qualitystandards for clinical trials under the principles of the International cooperation onharmonization of Technical Requirements for Registration of Veterinary Medicinal Products (VIch).VESO Vikan also offers monitoring services for trials runaccording to gcP at independent trial locations where we useour experience and dedication to vouch for valid trial conduct.

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The Veso organisaTionVESO Vikan is part of the VESO Organisation;Veterinærmedisinsk Oppdragssenter aS (VESO), centreof Veterinary contract Research and commercialServices Ltd., Oslo. VESO was established in 1988 andhas over 20 years of experience with veterinary vaccines.VESO consists of VESO Vikan and VESO Pharmacy.

Veso pharMacyVESO Pharmacy was established in 2008 and is co-situated with VESO’s head office at adamstua in Oslo. e pharmacy distributes approved vaccines for animals in norway, in addition to pharmaceuticals anddisinfectants. VESO Pharmacy represents a neutral linkbetween vaccine producers and veterinary practitioners,aiming to provide the best possible service to bothparties.

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aVs chile (noFiMa, Veso and sinTeF)aVS chile was established in august 2007 as a collaboration between akvaforsk (nofima), VESO andSInTEF Fisheries and aquaculture. e main objectiveof aVS chile is to develop and make accessible scientificand technological knowledge for the completeaquaculture value chain in chile. aVS chile covers a widerange of scientific competences in feed and nutrition,genetics and reproduction, health management and

vaccination, animal welfare,farming technology andengineering and final productprocessing and quality. aVSchile aims to create knowledge for a profitable, healthyand sustainable aquaculture industry, as well as to promote the interchange of knowledge in aquaculturebetween chile and norway. www.avs-chile.cl

www.veso.no

VESO VikanVikan, N-7800 NamsosTelephone: +47 74 21 77 70Telefax: +47 74 21 77 71www.veso.no/veso-vikan

VESO Pharmacy & Head OfficeUllevålsveien 68, PO Box 300 Sentrum, N-0103 OsloTelephone: +47 22 96 11 00Telefax: +47 22 96 11 11www.veso.no

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