Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf ·...

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Vertebral and Paravertebral Diseases John R. Hesselink, M.D. Department of Radiology University of California San Diego

Transcript of Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf ·...

Page 1: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Vertebral and

Paravertebral Diseases

John R. Hesselink, M.D.

Department of Radiology

University of California

San Diego

Page 2: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Vertebral / Paravertebral Disease

Metastatic disease

Primary bone tumors

Bone marrow disease

Paraspinal tumors

Infection

(Extradural)

Page 3: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 72 y/o man with esophageal CA

Sag T1 Sag T2 T1-Gd-FS

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Breast Metastases

T1 FSE STIR T2 FSE

Page 5: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 28 y/o female with back

pain & urinary incontinence

569

Page 6: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

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Dx: Lymphoma

{Page 3}

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Dx: Diffuse Breast metastases

History: 64 y/o woman with back pain

547

Page 9: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Diffuse Prostate metastases

History: 62 y/o man with back pain

548

Page 10: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Vertebral Compression

Marrow signal intensity

Signal pattern on T1WIs

Pedicles & posterior elements

Paraspinal mass

Enhancement features

Diffusion properties

Benign vs. Malignant

Page 11: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Breast Metastases

T1 FSE STIR T2 FSE

Page 12: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 70 y/o woman with back pain

545

Page 13: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Renal cell CA

{Page 2}

Page 14: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Traumatic Vertebral Fracture

3 Weeks Ago

LE 1-2

Page 15: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Benign Vertebral Collapse

LE 3-5

Page 16: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

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Biopsy negative for tumor

{Page 3}

Page 18: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Chronic Benign Vertebral Collapse

Page 19: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Chronic Vertebral Collapse with a Subacute

Endplate Compression

Page 20: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Acute Vertebral Fracture

T2 FSE

T1 FSE STIR

Page 21: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Vertebral Body Fracture

T2 FSE

T1 FSE

STIR

Page 22: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Spinal Metastases

Post Radiation Therapy

TD 40

Page 23: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Vertebral Hemangioma 222

History: 62 y/o man with spasms

in the mid-back

Page 24: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 55 y/o man with progressive

leg weakness for 6 months

662 - 2176511

Page 25: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Vertebral hemangioma

{Page 2}

Page 26: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Primary Bone Tumors

Osteosarcoma

Chondrosarcoma

Osteoblastoma

Aneurysmal bone cyst

Giant cell tumor

Osteoid osteoma

Eosinophilic granuloma

Vascular tumors

Page 27: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 55 y.o. man

with leg weakness

31

Page 28: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Chondrosarcoma

Leg weakness

{Page 2}

Page 29: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Jerry Dwek, Rady Children’s Hospital of San Diego

Osteoblastoma

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History: 11 month male

Page 31: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Osteochondroma Marvin Nelson, Children’s Hospital of Los Angeles

{Page 2}

Page 32: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Jerry Dwek, Rady Children’s Hospital of San Diego

Aneurysmal Bone Cyst

Page 33: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Aneurysmal Bone Cyst

Mark Halsted & Elizabeth Ey, Cincinnati Children’s Hospital

Page 34: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

{Page 2}

Page 35: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Jerry Dwek, Rady Children’s Hospital of San Diego

Osteoid Osteoma

Page 36: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Langerhans Cell Histiocytosis

Jerry Dwek, Rady Children’s Hospital of San Diego

Page 37: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 67 y/o man with sacral pain

with sitting & kneeling

766 – VA7495

Page 38: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Sacral chordoma

{Page 2}

Page 39: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 41 y.o. female with low

back and buttock pain

67

Page 40: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Sacral metastasis -

Breast carcinoma

{Page 2}

Page 41: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Bone Marrow Disease

Metastatic disease

Tumors of blood cell origin

Blood dyscrasias / anemias

Radiation therapy

Page 42: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 65 y/o woman with back pain & progressive

leg weakness & gait problem for 2 months

656

Page 43: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Plasmacytoma

{Page 2}

Page 44: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 53 y/o woman with back pain &

bilateral foot numbness

692

Page 45: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Plasmacytoma &

Multiple myeloma

{Page 2}

Page 46: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Epidural lymphoma

History: 32 y/o man with back pain

557

Page 47: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Leukemia

Sag T1 Sag T2 FS T1-FS post contrast

Evelyne Fliszar, UC San Diego

Page 48: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 54 y/o woman with CLL & right foot numbess

773 - 19113240

Sag T2

Sag T1

T1-FS post contrast

Page 49: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Anemia of chronic disease

History: 54 y/o woman with chronic lymphocytic

leukemia, anemia, & s/p bone marrow transplant

714

Page 50: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 35 y/o man with chronic

leg ulcer for 4 months

517

Page 51: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Staph osteomyelitis

{Page 2}

Page 52: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 40 y/o man with worsening

back & abdominal pain for 3 weeks

653

Page 53: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: TB spine

{Page 2}

Page 54: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 50 y/o man with AIDS,

hepatitis B & back pain

578

Page 55: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Staph osteomyelitis

& psoas abscesses

{Page 2}

Page 56: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 30 y/o man with neck pain

371

Page 57: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: IVDA - Staph osteomyelitis

{Page 2}

Page 58: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Cocci Osteomyelitis

CC 1-2

Page 59: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

{Page 2}

Page 60: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 23 y/o male IVDA who had

an MVA following an overdose

162

Page 61: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Staph epidural abscess

{Page 2}

Page 62: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 46 y/o woman developed left arm

pain and difficulty swallowing 1 week post

anterior cervical diskectomy & fusion

595

Page 63: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Retropharyngeal abscess

{Page 2}

Page 64: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 40 y/o male with fever,

back pain, and a T6 sensory level

423

Page 65: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Epidural abscess

{Page 2}

Page 66: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

422

History: 73 y/o female with a urinary

tract infection and progressive lower

extremity weakness and hyperreflexia

Page 67: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Epidural abscess

{Page 2}

Page 68: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

217

History: 68 y/o woman developed leg

weakness following hip surgery

Page 69: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Epidural Hemorrhage

(Lab: INA = 3.0)

She also had an epidural catheter

for pain control & was on coumadin

for deep vein thrombosis

{Page 2}

Page 70: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 16 y/o male with back pain

since a fall 2 weeks ago

299

Page 71: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Subacute epidural

hematoma

Back pain

{Page 2}

Page 72: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 43 y/o man with chronic

progressive morning neck pain

386

Page 73: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: OPLL

{Page 2}

Page 74: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

History: 37 y/o man with bilateral leg pain

166

Page 75: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Neurofibromatosis, Type 1

{Page 2}

Page 76: Vertebral and Paravertebral Diseases - UCSDspinwarp.ucsd.edu/NeuroWeb/PPT/sp-vertebral-45.pdf · Vertebral / Paravertebral Disease Metastatic disease Primary bone tumors Bone marrow

Dx: Abdominal aortic aneurysm

History: 69 y/o woman with back pain

323