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___________________________________________________________________________ 24 rue du champ de l’Alouette - 75013 Paris - France - RCS PARIS B 418 126 710 5 98B04764

Tel: +33.1.53.62.24.00. Fax:+33.1.53.62.00.10.

Venus Explorer Processing Technical specifications

Venus Explorer Processing Server software

Web base application sever; tomcat Apache technology.

Include Dicom server and MySQL database management.

Venus Explorer Processing Server

Venus Explorer Processing software Venus Explorer Processing is a null client installation and a navigator is used to access to the

applications.

Venus Explorer Processing Client licences are floating (concurrent); allow the software to be loaded

on multiple PC’s for concurrent user login.

Some third party options (i.e. Cedars) are either fixed (node-locked) or floating (concurrent).

Fixed Client licence is node-locked to a certain IP address on the network.

Floating Client licence provides access from any Windows PC on the network (with

compatible graphic board & memory) and concurrent access is only limited by the number of

Venus Explorer Processing Client licences purchased.

Venus Explorer Processing™ - run on any hardware (PC, MAC,…); the process is done an

application server; client access through a web navigator.

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Venus Processing™

NUCLEAR MEDICINE, PET/SPECT/CT/MR

MULTIMODALITY IMAGING SOLUTIONS

CONSISTENCY

Uniform reading and processing environment for all your SPECT and PET cameras.

With Venus Explorer Processing, you are no longer bound to a particular camera workstation.

Venus Explorer Processing gives you complete functionality to process or review all NM scans

regardless of camera vendor, using a suitable PC with secure access to the department server.

CLINICALLY SUPERIOR

Delivers the full spectrum of clinical NM and multi-modality applications

Dedicated to deliver advance co-registration fusion, multimodality viewing and quantification

specialized tools.

Delivers a unique PET/SPECT/CT/MR multi-modality viewer completely operator configurable with

advanced “Tumor tracking” feature.

nicesoft endless continues its cooperation with leading worldwide medical institutions in order to

provide you with the most complete, state of the art, while innovative multimodality clinical software

library able to meet your needs.

CUSTOMIZABLE, FLEXIBLE & SECURE

Easy to used interactivity: Venus Explorer Processing scales its functionality to the expert level of

the user based on logon credentials.

Venus Explorer Processing provides the full flexibility to expert users and limits the available

functionality to the occasional user, keeping the system simple enough for those users and avoiding

misinterpretations due to the operator error.

Use processing and display scripts and supply a powerful user preference mechanism to control them.

Venus Explorer Processing uses processing and display scripts and supply a user preference mechanism

to control them; permits a customization of display pages through a of lay-out editor which permits to

change, resize, delete or create display objects.

Easy to develop and maintain through modularization.

Incorporate mechanism to create graphic layout.

Highly display-centric; enhance 3-D displays, cine and curves.

Numerous user interactions to display.

Message and dialogue displays.

Multiple monitor configuration: possible use of multi-screens , each screen being able to display a

different page.

Multiple resolutions for the monitors handled

Unique use of screen - all formats.

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Monitors

Venus Explorer Processing workstations can be configured with different size monitors, accepting any

screen resolution, in particular 16x9 formats, and multiple screen configurations; can come with single,

dual, triple, quad or other multi-monitor configurations (up to 8 monitors) in order to best fit with your

needs. Venus Explorer Processing software library comes with multi-monitor synchronization for easy

review of multiple modalities or serial studies.

Facilitates port to other vendors’ environnent.

Venus Explorer Processing

Offers the possibility of Floating Client software licenses.

Venus Explorer Processing Client license allows access on the Venus Explorer Processing server &

Venus Explorer Processing applications.

Venus Explorer Processing Client licences are floating (concurrent).

Some third party options (i.e. Cedars) are either fixed (node-locked) or floating (concurrent).

SPECIALIZED

Venus Explorer Processing specializes in customized, turnkey Nuclear Medicine,

SPECT/PET/CT/MR and multimodality imaging solutions including seamless connectivity, uniform

processing platform, multi-format archiving & remote reading distribution.

CUSTOMER FOCUSED

All Venus Explorer Processing software can be tailored to meet specific Nuclear Medicine and

SPECT/PET/CT/

MR department needs. NICESOFT features personalized onsite and remote customer support to assist

& support you quickly & efficiently.

EFFICIENT ARCHITECTURE

The Venus Explorer Processing Client/Server architecture provides an efficient infrastructure for

data and application management.

Allows remote-access

The Venus Explorer Processing data architecture is very much like a PACS system as it deploys a

redundant central database for all NM data.

Venus Explorer Processing is fully DICOM compliant and integrates non-DICOM compliant sources

through an optional system.

Use sophisticated DICOM library; include Cardio (EKG, etc.)

Expandable: Venus Explorer Processing is the first system of its kind that provides you completely

expendable application delivery architecture no matter what the future may hold.

COST EFFECTIVE

Client runs on standard PC hardware.

Applications reside on the server side and are very fast downloaded to the client when needed.

Processing is performed on the client.

Each clinical application can be licensed separately which means you only pay for the software you

really need.

Also, it allows you to start with Venus Explorer Processing with a minimum investment and add more

users and capabilities over time.

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PACS COMPATIBLE

Designed as the NM complement of modern PACS systems with integration support for legacy cameras

and data formats.

OPEN

Allows for tight integration of common third party applications (e-g: cardiology - Cedars / Emory /

4DMSPECT Michigan).

BLAZINGLY FAST

The Venus Explorer Processing display engine capitalizes on the extreme processing power

available in modern graphics cards: the utilization of GPU for display and computations maximizes

performance while reducing CPU loads (processing on client stations).

Venus Explorer Processing architecture utilizes the available power of OpenGL to the fullest extend.

The result is immediately obvious as the display interactions on large datasets and 3D renderings are

blazingly fast.

Offers an instant access to data loaded from PACS & server.

NON OBSOLESCENCE

Fully protected against future changes in instrumentation.

VENDOR NEUTRAL

Venus Explorer Processing is a vendor-neutral multimodality processing & multimodality platform

for Nuclear Medicine which maintains data integrity across all vendor platforms, providing you with all

freedom of choice for new cameras & PET/CT scanners purchases.

QUALITY DRIVEN

All Venus Explorer Processing software library is CE Mark (Europe).

Venus Explorer Processing complies with HIPAA, EU privacy laws.

NICESOFT is ISO & CMRD certified.

VALIDATED

Venus Explorer Processing software library & applications are validated & tested and have been used clinically

for part of the software library since 1998.

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Venus Processing Functional specifications

General Clinical Applications

General NM Viewer Generic viewer for NM images in static, dynamic, wholebody, or planar gated format and secondary

captures from all modalities.

Features include:

Display functions: window leveling, color scale selection, zoom, pan, magnify, colorize

Measurement tool

Independent or synchronized window leveling

SPECT-CT (multimodality viewing)

Clinical application for review and analysis of SPECT/CT studies.

Features include:

Standardized orthogonal slice displays

Display functions: triangulation, window leveling, color scale selection, slice alignment, cine

controls, zoom, pan, magnify, colorize

Measurement tool

User definable CT window presets

Distance weighted maximum intensity projections (MIP)

Fusion display mode based on variable alpha blending and/or variable thresholding

Manual registration adjustment (translations, rotations)

3D region analysis based on iso-contouring

Study comparison (follow-up)

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User definable hotkeys for commonly used functions

Dedicated Lesion, Linking, and Registration Managers

User specific preferences based on logon credentials

Compatible with all SPECT and hybrid SPECT/CT scanner models

Customized layouts through display scripts

Volume rendering option

Volume rendering generation.

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PET-CT-Onco (multimodality viewing)

Clinical application for review and analysis of PET/CT studies.

Features include:

Standardized orthogonal slice displays

Display functions: triangulation, window leveling, color scale selection, slice alignment, cine

controls, zoom, pan, magnify, colorize

Measurement tool

Automatic window saturation function for PET

User definable CT window presets

SUV computation

Distance weighted maximum intensity projections (MIP)

Fusion display mode based on variable alpha blending and/or variable thresholding

Manual registration adjustment (translations, rotations)

Tumor-tracking analysis using auto 3D lesion contouring

Study comparison (follow-up) with automatic rigid CT/CT registration

User definable hotkeys for commonly used functions

Dedicated Lesion, Linking, and Registration Managers

Export of to RT systems

User specific preferences based on logon credentials

Compatible with all PET and hybrid PET/CT scanner models

Customized layouts through display scripts

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Bones

Clinical application for review and analysis of bone scintigraphy studies.

Features include:

Combined display of Static, Dynamic, WB, and SPECT images

Display functions: triangulation, window leveling, color scale selection, slice alignment, cine

controls, zoom, pan, magnify, colorize

Measurement tool

Bladder masking tool

Region of interest analysis (ROI)

3-phase bone analysis

Distance weighted maximum intensity projections (MIP)

User definable hotkeys for commonly used functions

User specific preferences based on logon credentials

Customized layouts through display scripts

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Gastric Reflux

Clinical application for review and analysis of gastric reflux stimulation studies.

Features include:

Manual ROI definition

Time activity curve analysis

Compatible with dynamically acquired datasets

User specific preferences based on logon credentials

Customized layouts through display scripts

Gastric Emptying

Clinical application for review and analysis of gastric emptying studies.

Features include:

Analysis of stomach function

Separate analysis of solid and liquid phase

Compatible with dynamic or multiple static data

Analysis of dynamic esophageal function

Customized layouts through display scripts

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Sentinel Node

Display of two static images with a specialized gray scale optimized for the high maximum counts

typical in sentinel node imaging.

Thyroid and Parathyroid

Clinical application for review and analysis of thyroid uptake, thyroid and parathyroid studies.

Features include:

Uptake calculation based on pre/post injection dose image

Relative R/L lobe uptake

Either technetium or iodine studies

Fusion of marker and anterior thyroid images

Subtraction analysis of dual isotope (Tc, Tl) parathyroid studies

Dual phase (Sestamibi) parathyroid studies

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Renal

Clinical applications for review and analysis of renography studies.

Features include:

Analysis of kidney function

Auto region of interest with manual override

Time activity curve analysis

Split function

Measurement tool

Compatible with Tc-99m-DTPA, Tc99m-MAG3

Multi-phase analysis

Separate applications for handling of Anterior, Transplant and Single Kidney

scenarios.

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VenusCardiac

Clinical application for reconstruction, processing and display of gated and ungated tomographic

cardiac data.

Access to optional Cedars MoCo motion correction module for the automatic and manual

correction of SPECT acquisition motion artifacts. Pattern matching and segmentation

algorithms are used in conjunction to minimize motion error metrics over the set of acquired

projections; the resulting motion corrected projections are then presented to the operator for

validation or modification.

Reorientation, zooming and masking of reconstructed data.

Slice review displays

Direct access to quantification with third party applications such as Cedars Sinai QGS-QPS

etc.

MUGA

Clinical application for review and analysis of planar gated blood pool studies.

Features include:

Automatic segmentation of left ventricle (ED, ES, and background ROI, with manual

override)

Unique Fourier based filtering technique for improved visualization of wall motion

Display functions: window leveling, color scale selection, slice alignment, cine controls,

zoom, pan, magnify

Amplitude/Phase analysis

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Pseudo3D cine display (topographic dynamic mapping of counts)

Multi-study comparison (multiple exercise levels, or follow-up)

Right ventricle processing options (RVEF, RV volumes)

Compatible with most acquisition protocols (matrix size, #frames/cycle)

Customized layouts through display scripts

Planar Lung Analysis Clinical application for review and analysis of planar lung studies. Features include:

Analysis of Ventilation, Perfusion, or Ventilation + Perfusion

Static image display of all acquired orientations

Display functions: window leveling, color scale selection, zoom, pan, magnify, colorize

Measurement tool

Automatic 2-segmental quantification of anterior and posterior images ;

Generation of geometric mean images

User definable hotkeys for commonly used functions

User specific preferences based on logon credentials

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LungSPECT-CT An application for reconstruction, display and linked triangulation of ventilation and perfusion SPECT

studies.

Includes creation of reprojection images and MIRegistration of perfusion and ventilation series.

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Utilities

MIRegister A clinical application that provides direct access to the Mutual Image Information Registration

utilities.

Automatic process & manual adjustments