Vascularization and Cortex of the Brain-2011

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    Central Nervous System

    Brain

    Spinal cord

    Peripheral Nervous System

    Cranial nerves

    Spinal nerves

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    Prosencephalon

    Telencephalon

    (Cerebrum)

    Diencephalon

    (Thalamus,

    Hypothalamus)

    Mesencephalon

    Rhombencephalon Metencephalon (Pons)

    Myelencephalon

    (Medulla Oblongata)

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    Planes of the brain

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    SAGITAL SECTION

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    LATERAL ASPECT

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    FRONTAL SECTION

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    GANGLIA BASALIS

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    Epidural space Meningea artery

    Subdural space

    Superficial cerebral vein andsinuses

    Subarachnoid space Filled by CNS

    Cerebral artery

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    Lateral ventricle (pair)

    Frontal, occipital and temporalhorn

    foramina of Monro third

    ventricle Third ventricle

    Aqueduct of Sylvii forth

    ventricle Forth ventricle

    Laterally foramen luschka

    subarachnoid space

    Medially foramen magendi

    subarachnoid space

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    Produced by choroid plexus in ventricles

    Secreted 0.5 ml/min 300 ml/day

    Circulation Occupies subarachnoid spaces of the brain and MS Vert Sacral II

    Reabsoption Return to the sinus venosus via arachnoid granulation

    due to the differences of pressure

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    Arachnoid granulation

    Sinus sagitalis

    superior

    CSF

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    Absorption of CSFreturn to the blood

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    Blood supply of the brain

    Vertebral-basilar a

    Internal carotid a

    BrainstemCerebellum

    Spinal cord

    Hemisphere Cerebri

    Diencephalon

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    VC IV : bifurcatio A.

    carotis communisA.carotis externa andinterna

    Perforate the skullcarotid canal of temporal

    bone caverosus sinus perforate duramater subarachnoid space

    Divided into A. cerebrianterior and A. cerebrimedia

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    A. vertebrobasilarisalis

    A. Subclvia

    A. Vertebralis

    For. transversalia VC 1-7

    foramen magnum

    A. Basilaris

    A. cerebri posterior

    CIRCULUS WILLISI

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    A. cerebri media Cortical branch lateral surface of hemisphere

    Central branch caudate nuclei, internal capsule

    A. cerebri anterior Cortical branchmedial surface of cortex

    Central branch caudate nuclei, internal capsule

    A. ophtalmica Supply frontal area, eye, frontal n ethmoid sinus, dorsum of nose

    A. communicans posterior Join posterior cerebral a circle of Willis

    A. choroidal anterior Ends in choroid plexus

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    Centralbranches A. striata

    lateralis

    Upper division A. prefrontal,

    A. precentral,

    A. central,

    A. postcentral,

    A. parietal

    Lower division A. middle temporal, A. temporal anterior, A.

    temporo-occipital, A. angular

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    A. pericallosal: Corpus callosum

    A. callosomarginal

    Paracentral lobe

    Gyrus frontalis superior

    A. Orbitofrontal: frontal lobe

    A. polar frontal: Frontal pole

    A. striae medialis : Capsula interna

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    Medial branches A. calcarine

    A. callosal

    A. parieto-occipital

    Lateral branches A. temporal anterior

    A. temporal posterior

    A. occipito temporal

    A. choroidal posterior Plexus choroideus of lateral

    ventricle

    Central branches A. Thalamoperforating

    A. Thalamogeniculate

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    Basilar a

    Posterior cerebral

    Posteriorcommunicating

    Internal carotid

    Anterior cerebralAnterior

    communicating

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    V d i

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    Venous drainage

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    Normal perfussion 50 ml/100 gr CNS/min Neurons stop the signal 20 ml/100 g

    CNS/min Neurons stop the signal after 5 min cardiac

    arrest

    Destructive necrosis 10 ml/100 gCNS/min

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    is a sheet ofneural tissue that is outermost to the

    cerebrum of the mammalian brain.

    It plays a key role in memory, attention, perceptualawareness, thought, language, and consciousness.

    It is constituted of up to six horizontal layers, in

    terms of neurons and connectivity.

    The human cerebral cortex is 24 mm (0.08

    0.16 inches) thick.

    50 billion neurons and 500 billion neuroglia cells

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    B d A

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    Brodmanns Area (47 AREA)

    MEDIAL ASPECT

    LATERAL ASPECT

    1,2,3,4,5,6,7,8,9,10,11,1217,18,19,20,23,24,25,28,

    31,32,34,36,37,38

    1,2,3,4,5,6,7,8,9,10,11,17,

    18,19,20,21,22,36,37,38,39,

    40,41,42,44,45,46,47

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    Motor Primary area 4

    Supplementary area 6

    Sensory 3,1,2 primary somatic sensory

    5 somatic sensory association

    40 secondary somatic sensory

    LESI PADA sensoric area: loss of vibration, poprioception, fine

    touch, crude touch pain, and

    thermoception

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    Primary somasthetic area (area 3,1,2)

    Secondary somasthetic area

    Somasthetic association area ( 5, 7)

    Occipital lobe

    Primary visual area (17)

    Secondary visual area (18, 19)

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    Primary auditory area (41, 42) Secondary auditory area (22)

    Sensory speech area of WERNICKE Active listening :21, 37, 39, 46

    Passive listening: 9, Listen to tones

    Precentral

    Posterior region (area 4)

    Primary motor area Anterior region

    Secondary motor area

    Reading:area 44, 45, 46

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    Brocas: speaking or use the

    wordsMotor speech

    function, 44, 45

    Lesi: Expressive aphasia

    Wernicke: understanding the

    spoken word Sensory

    speech function, area 22

    Lesion receptive aphasia

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    TIA (transient ischemic attack)

    Strokes

    Hemorrhagic Cerebral hemorrhage

    Ischemic Cerebral infarction

    Aneurysma

    Arteriovenosus malformation (AVM)

    Cerebrovascular accident HEAD INJURY

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    A stroke is an interruption of the blood supply toany part of the brain:

    Hemorrhagic strokes An incident of vascular bleeding into the brain

    Ischemic strokes (sudden vascular insufficiency) Trombus (a blood clot formed within a vessel)

    Embolus ( a blood clot is carried along in the blood stream)