V Measure particles within your process! · The design of multiphase reactors usually requires...
4
Measure particles within your process! SOPAT-VI-System The SOPAT-VI Probe is an inline process particle measurement technique that analyses particle sizes and distributions in real-time. The technology is based on high quality photo-optical image acquisition, integrated with an innovative image analysis soft- ware. Particles like drops, bubbles, grains and cells are rapidly and reliably analysed even when present in high concentrations. Measure and characterize droplets, grain, bubbles or any kind of particles
Transcript of V Measure particles within your process! · The design of multiphase reactors usually requires...
Measure particleswithin your process!
SOPAT-VI-System
The SOPAT-VI Probe is an inline process particle measurement technique that analyses
particle sizes and distributions in real-time. The technology is based on high quality
photo-optical image acquisition, integrated with an innovative image analysis soft-
ware. Particles like drops, bubbles, grains and cells are rapidly and reliably analysed
even when present in high concentrations.
Measure and characterize droplets, grain, bubbles or any kind of particles
SOPAT GmbHBoyenstr. 41, 10115 Berlin, Germany
Contact us at:
tel: +49-30-398-2020-00 mail: [email protected]: +49-30-398-2020-49 web: www.sopat.eu
SOPAT-V
I / IV
SOPAT-M
M
SOPAT-I
nView
MM-Li
SOPAT-MM
MM-Ho Ma Pl Sc Pa Kr -
InViewSOPAT-VR / VI
0.9 – 90
0.295
270
24.5
1.4571
7 4
CE, IP65, CIP/SIP
Aluminum, 1.4404
1.4401, 1.4571, 2.4602 (Hastelloy C22)
-0.5 – 10
-10 – 250
-10 – 45
-0.5 – 40 -0.5 – 3
0 – 50
1.4404
CE, IP65
320 – 2000
12
-0.5 – 150
-50 – 450
-10 – 65
0.1 – 20 Hz
0.385
1 – 170 1.5 – 280
0.64
3 – 350
0.8
9 – 1200
2.7
19.5 – 2600
5.85
70 – 9300
21
320
20
260 – 26000
60
215
130
Product category
Product model
Measuring range [microns]
Field of View [mm]
Probe length [mm]
Probe diameter [mm]
Pressure range [bar]
Temperature range [° C]
Back-end temp. [° C]
Probe window material
Probe tube material
Probe housing material
Weight (without cable) [kg]
Focusing
Frame rate
Certifications
Manual ManualAutomatic
Sapphire/BK7 Sapphire Quartz glass
The SOPAT-VI probe and system will be
adjusted to meet your specific process
requirements. The probe is easily installed
using standard valves, flanges or muffs.
Configuration for existing and new plants
and equipment is straightforward and will
be done for you by SOPAT.
Performance –direct analysis sets new standards
Application examplesGas-liquid
The design of multiphase reactors usually requires expensive experimental investiga-
tions. For an exact prediction of heat and mass transfer and reaction or growth rates
during fermentation in a stirred vessel or bubble column, exact knowledge of the inter-
facial area is required. SOPAT delivers this information.
Liquid-liquid
Homogeneous catalytic liquid-liquid reactions are cornerstones for “green chemistry”.
Applied surfactants make the drop size distributions in these multiphase systems com-
plex. For process development, knowledge of the condition of dispersion and particle
size distribution is essential. SOPAT delivers this information.
Solid-liquid
The real-time quantification of particle size distributions dependent on time and loca-
tion is essential for optimizing the process design and a vital component in fully-auto-
mated production techniques. Documentation and knowledge of in-process parameters
aid in achieving an increased process transparency according to GMP regulations.
SOPAT delivers this information.
Measurement principle
To get statistically reliable Particle Size Distribution, data sets with a large number of particles have to be measured. The SOPAT
process starts with the acquisition of a significant amount of raw image data, followed by the particle recognition, which consists of
three main steps:
1. Pattern recognition by correlation of pre-filtered images with search patterns
2. Pre-selection of plausible circle coordinates
3. Classification of each of these by an exact edge examination.
The computation time is proportional to the quantity of pixels being processed and is up to five hundred times faster than manual
counting.
Particles are part of a great variety of processes and products. Characterizing and understanding them is, therefore, relevant not
only for the laboratory, but also for production lines. Exactly that, however, is complex and challenging.
Our technology measures particle size distributions in-situ and in real-time. Our systems operate efficiently and accurately even in
high concentrations. The SOPAT-VI system accelerates experimental lab work, ensures reproducibility of results and opens up new
opportunities for real-time process monitoring and control.
Our comprehensive software package resides on a high performance workstation and is accessible via a graphical user interface
which is clearly arranged and easy to use. The results, including number density distribution (q0), cumulative number distribution
(Q0), volume distribution (Q3) and different mean diameters (d10, d32, d50, d90 a.s.o.) can be displayed. These output parameters form
the basis for real-time process control.
The SOPAT-VI is an inline microscope containing a smart image analysis software to deliver robust and accurate real-time particle
detection and characterization. The results include real-time particle size quantification of the system within a size range of 1 to
10,000 μm. This approach allows full automation and process control, which leads to the following process optimization benefits:
• Instant error detection
• Waste reduction and output growth
• Product quality improvement
• Increased process transparency and safety
Technology –precision by means of image analysis
SOPAT-Image Analysis
1. Image Acquisition 2. Pre-filtering, Norming 3. Object Classification
SearchAlgorithm Definition
ParticleDetection
ParticleSize
Distribution
Performance –direct analysis sets new standards
Application examplesGas-liquid
The design of multiphase reactors usually requires expensive experimental investiga-
tions. For an exact prediction of heat and mass transfer and reaction or growth rates
during fermentation in a stirred vessel or bubble column, exact knowledge of the inter-
facial area is required. SOPAT delivers this information.
Liquid-liquid
Homogeneous catalytic liquid-liquid reactions are cornerstones for “green chemistry”.
Applied surfactants make the drop size distributions in these multiphase systems com-
plex. For process development, knowledge of the condition of dispersion and particle
size distribution is essential. SOPAT delivers this information.
Solid-liquid
The real-time quantification of particle size distributions dependent on time and loca-
tion is essential for optimizing the process design and a vital component in fully-auto-
mated production techniques. Documentation and knowledge of in-process parameters
aid in achieving an increased process transparency according to GMP regulations.
SOPAT delivers this information.
Measurement principle
To get statistically reliable Particle Size Distribution, data sets with a large number of particles have to be measured. The SOPAT
process starts with the acquisition of a significant amount of raw image data, followed by the particle recognition, which consists of
three main steps:
1. Pattern recognition by correlation of pre-filtered images with search patterns
2. Pre-selection of plausible circle coordinates
3. Classification of each of these by an exact edge examination.
The computation time is proportional to the quantity of pixels being processed and is up to five hundred times faster than manual
counting.
Particles are part of a great variety of processes and products. Characterizing and understanding them is, therefore, relevant not
only for the laboratory, but also for production lines. Exactly that, however, is complex and challenging.
Our technology measures particle size distributions in-situ and in real-time. Our systems operate efficiently and accurately even in
high concentrations. The SOPAT-VI system accelerates experimental lab work, ensures reproducibility of results and opens up new
opportunities for real-time process monitoring and control.
Our comprehensive software package resides on a high performance workstation and is accessible via a graphical user interface
which is clearly arranged and easy to use. The results, including number density distribution (q0), cumulative number distribution
(Q0), volume distribution (Q3) and different mean diameters (d10, d32, d50, d90 a.s.o.) can be displayed. These output parameters form
the basis for real-time process control.
The SOPAT-VI is an inline microscope containing a smart image analysis software to deliver robust and accurate real-time particle
detection and characterization. The results include real-time particle size quantification of the system within a size range of 1 to
10,000 μm. This approach allows full automation and process control, which leads to the following process optimization benefits:
• Instant error detection
• Waste reduction and output growth
• Product quality improvement
• Increased process transparency and safety
Technology –precision by means of image analysis
SOPAT-Image Analysis
1. Image Acquisition 2. Pre-filtering, Norming 3. Object Classification
SearchAlgorithm Definition
ParticleDetection
ParticleSize
Distribution
Measure particleswithin your process!
SOPAT-VI-System
The SOPAT-VI Probe is an inline process particle measurement technique that analyses
particle sizes and distributions in real-time. The technology is based on high quality
photo-optical image acquisition, integrated with an innovative image analysis soft-
ware. Particles like drops, bubbles, grains and cells are rapidly and reliably analysed
even when present in high concentrations.
Measure and characterize droplets, grain, bubbles or any kind of particles
SOPAT GmbHBoyenstr. 41, 10115 Berlin, Germany
Contact us at:
tel: +49-30-398-2020-00 mail: [email protected]: +49-30-398-2020-49 web: www.sopat.eu
SOPAT-V
I / IV
SOPAT-M
M
SOPAT-I
nViewMM-Li
SOPAT-MM
MM-Ho Ma Pl Sc Pa Kr -
InViewSOPAT-VR / VI
0.9 – 90
0.295
270
24.5
1.4571
7 4
CE, IP65, CIP/SIP
Aluminum, 1.4404
1.4401, 1.4571, 2.4602 (Hastelloy C22)
-0.5 – 10
-10 – 250
-10 – 45
-0.5 – 40 -0.5 – 3
0 – 50
1.4404
CE, IP65
320 – 2000
12
-0.5 – 150
-50 – 450
-10 – 65
0.1 – 20 Hz
0.385
1 – 170 1.5 – 280
0.64
3 – 350
0.8
9 – 1200
2.7
19.5 – 2600
5.85
70 – 9300
21
320
20
260 – 26000
60
215
130
Product category
Product model
Measuring range [microns]
Field of View [mm]
Probe length [mm]
Probe diameter [mm]
Pressure range [bar]
Temperature range [° C]
Back-end temp. [° C]
Probe window material
Probe tube material
Probe housing material
Weight (without cable) [kg]
Focusing
Frame rate
Certifications
Manual ManualAutomatic
Sapphire/BK7 Sapphire Quartz glass
The SOPAT-VI probe and system will be
adjusted to meet your specific process
requirements. The probe is easily installed
using standard valves, flanges or muffs.
Configuration for existing and new plants
and equipment is straightforward and will
be done for you by SOPAT.
