Uworld Notes
description
Transcript of Uworld Notes
Question Id
Main Division
Sub Division Notes
2157 Internal Medicine Cardiology Murmur radiating to axils with soft s1 -> MR
2161 Internal Medicine Dermatology impressive cellulitis -> anceph (cefazolin) which is IV vs. cellulitis + pus or in area of high MRSA ->
add Vanco
2164 Internal Medicine Cardiology loop diuretics -> hypo-k and -mg -> Vtach -> get electrolytes and check digoxin level
2165 Internal Medicine Endocrinology
hyper-ca with unsuppressed pth and no urinary increase in calcium excretion -> receptor sensing problem in parathyroid and kidney -> familial hypocalciuric hypercalcemia vs. hyper-ca with unsupressed pth and increased urinary excretion -> primary hyperparathyroidism
2176 Internal Medicine Endocrinology Very high calcium, low PTH -> malignancy vs. High calcium, high PTH -> primary
hyperparathyroidism
2178 Internal Medicine Endocrinology sore throat and fever on PTU? -> check WBC for agranulocytosis!!
2180 Internal Medicine Endocrinology dilute blood + concentrated urine -> EUVOLEMIC hyponatremia 2/2 SIADH (NSAIDS potentiate
ADH) vs. renal failure/ kidney problem -> HYPERVOLEMIC hyponatremia
2184 Internal Medicine Endocrinology DKA diagnosis: blood glucose >250, blood ketones, acidosis (decreased pH or bicarb)
2190 Internal Medicine Endocrinology diabetic nephropathy -> control your BP to maintain GFR !!! 140/90 OK. Ace-i best (when starting,
monitor decline in GFR and hyper-K)
2191 Internal Medicine Endocrinology hormone OD, iodine OD, subacute painless lymophocytic, post-delivery -> thyrotoxicosis
(inflammed follicles leak thyroid hormones) -> decreased radioactive iodine uptake
2203 Internal Medicine GIT PRESSURE during vomiting -> ruptures submucosal ARTERIES in distal eso -> MALLORY WEISS
TEARS vs. eso varices-> submucosal VEINS from portal hypertension
2221 Internal Medicine Genitourinary left sided scrotal varicocele + blood in urine + polycythemia -> RCC???? -> CT that.
2228 Internal Medicine Genitourinary kidney stone? -> probs Calcium oxalate!! especially if fat malabsorption problem
2229 Internal Medicine Genitourinary Blood in UA but no cells -> rhabdo?
2236 Internal Medicine Genitourinary culture negative urethritis -> chlamydia (is cloaked!!)
2256 Internal Medicine Hem&Onc + VDRL -> confirm with ABs. lots of false postivies with SLE antiphospholipid AB syndrome
2269 Internal Medicine ID ALL SORTS OF THINGS can give you diarrhea in HIV-> send your stool for analysis before
picking an antibx...
2270 Internal Medicine ID CMV = Can't See Me on Monospot test. Also, usually no sore throat/lymphadenopathy.
2282 Internal Medicine Neurology LEWY body dementia -> see LIONS. FLUCTUATING cognitive impairment, parkinsonism motor
sx..
2287 Internal Medicine Neurology tremor that increases in intensity while reaching for object -> ESSENTIAL TREMOR, AD ->
Propranolol
2292 Internal Medicine Respiratory
gram negative -> CIPRO vs. anaerobe -> CLINDA (anaerobes above the diaphragm). CAP -> z-pack vs. levo (less healthy pt) vs. HCAP-> vanc (+) + zosyn (broad, pseudo) + cipro(-, pseudo) vs. ICU -> add gentamicin or imipenem?
2295 Internal Medicine Respiratory very sick alcoholic coughing -> aspiration pneumonia -> right lower lobe (can be upper if lying
down)
2305 Internal Medicine Rheumatology air or cartilage erosion -> crepitus. *osteoarthritis -> tylenol!
2582 Internal Medicine Hem&Onc UC -> surveillance colonoscopy every year after 8th year!!
2589 Internal Medicine Hem&Onc testicular cancer -> KILL FIRST AND INVESTIGATE LATER (surgery + chemo)-> high cure rate!!
:) **(NO BIOPSY OR NEEDLE ASPIRATION OR CANCER CELLS/SPERM WILL SPILL OUT)
2599 Internal Medicine Hem&Onc
if calcium >12 -> BAD hypercalcemia -> calcitonin, bisphosphonates, NS. *cancer -> parathyroid hormone related protein -> makes your bones break down -> hypercalcemia CALCIUM BREAKS YOUR BONES.
2602 Internal Medicine Respiratory ptosis -> eyelid droop (myasthenia, horner's) vs. proptosis/exopthalmous-> eye props out (grave's)
2608 Internal Medicine Hem&Onc Do you TRUST HER??? TRASTuzumab for HER2+ breast cancer. *cardiotoxic so echo before
starting. chemo/radiation after surgery = adjuvant.
2613 Internal Medicine Hem&Onc ONLY If positive for BRCA -> screen for Ovarian cancer with U/S +/- CA125
2615 Internal Medicine Hem&Onc most common type of lung cancer- > ADENOcarcinoma (solitary and in periphery), & remarkable
has NO ASSOCIATION WITH SMOKING!!
2616 Internal Medicine Hem&Onc febrile neutropenia -> PIPTAZ empirically after blood culture to get pseudo, or meropenem or
cefepime
2630 Internal Medicine Hem&Onc kidney stones + ulcers -> AD MEN 1 (hyperparathyroidism, pancreatic tumor/gastrinoma/
zollinger-ellison syndrome, pit tumor)
2632 Internal Medicine Hem&Onc constipation + thirsty -> HYPERcalcemia -> PTHrP???
2641 Internal Medicine Hem&Onc PO43- binds Ca2+, so tumor lysis syndrome -> increased everything except calcium.
2645 Internal Medicine Hem&Onc DM + DERMATITIS (NECROLYTIC MIGRATORY ERYTHEMA) + DIARRHEA -> GLUCAGONOMA
(PANCREATIC NEUROENDOCRINE TUMOR)
2645 Internal Medicine Hem&Onc mild DM + nec rash/diarrhea/anemia/weight loss -> glucagonoma!
2646 Internal Medicine Hem&Onc Progesterone before Pot for anorexia....does the pill make you fat?!?!
2649 Internal Medicine GIT tumor with diarrhea in small intest -> carcinoid syndrome vs. tumor with diarrhea in pancreas ->
VIPoma
2659 Internal Medicine Cardiology GET MAD (MAG) FOR TORSADES. if unstable-> defrilltate instead.
2662 Internal Medicine Poisoning dry as a bone, full as a flask, blind as a bat, mad as a hatter -> anticholineric tox -> give
physostigmine (cholinesterase inhibitor)
2663 Internal Medicine Cardiology brady + wheezing + hypotension -> BB overdose -> 1. atropine + fluids 2. glucagon 3. epinephrine
2695 Internal Medicine Cardiology systolic mumur radiation going to axilla + S3 + palpitations -> most likely Afib from MR from MVP
2731 Internal Medicine Cardiology month after MI -> LV aneurysm or pericarditis
2737 Internal Medicine Cardiology Troponin T Takes TEN days to return to normal. so use CK-MB (returns to normal within 1-2 days)
for recurrent heart attack.
2741 Internal Medicine Cardiology CHF in young person -> myocarditis 2/2 coxsackie B virus???
2745 Internal Medicine Cardiology STEMI: PTCA (door to ballon time < 90 min) better outcomes than fibrinolytics (door to needle
time <30 min).
2745 Internal Medicine Cardiology door to balloon time < 90 minutes (Percut transluminal coronary angioplasty PTCA)
2747 Internal Medicine Dermatology URI then herald patch-> xmas tree pattern -> pityriasis rosea
2760 Internal Medicine Dermatology elaine's painful stye from local process -> Hordeolum -> Hot compresses, I&Dvs. painless
granuloma rxn from obstructed gland-> chalazion -> if recurrent, biopsy to R/O gland cancer
2775 Internal Medicine Dermatology IgG against desmoglein in epidermis -> flacci blistering bullae -> pemphigus VULGARIS vs. IgG
and C3 at dermal epidermal junction (DEEPER) -> HARD blisters -> bullous pemphiGOLD
2775 Internal Medicine Dermatology Dig deeper for gold ( igG in dermal-epidermal layer for tense bulbous pemphigoid) Vs. Vulgaris
(vulgar, flaccid, superficial)
2786 Internal Medicine Electrolytes pneumonia -> hypoxia -> tachypnea, respiratory alkalosis -> renal compensation by decreasing
bicarb
2790 Internal Medicine Electrolytes pneumonia -> respiratory acidosis ( if COPD exacerbation) & metabolic acidosis (production of
lactate). are the lungs compensating for a metabolic acidosis? arterial pCo2= 1.5xbicarb +8
2796 Internal Medicine Electrolytes Winter's formula for respiratory compensation for DKA or metabolic acidosis: PaCO2 = 1.5xbicarb
+8
2812 Internal Medicine Electrolytes hypotension from septic shock (acidosis, low urine output, fever, tachypnea): 1. NS bolus 2.
Pressors only if NS fails
2813 Internal Medicine Electrolytes
vomiting: 1. lose gastric juice (HCl, NaCl)-> pancreas doesn't release bicarb -> bicarb increases in blood. 2. lose blood volume -> kidneys sense decreased Q -> aldosterone -> lose H+ and K+. -> hypokalemic, hypochloremic metabolic alkalosis
2817 Internal Medicine Electrolytes NON-AG metabolic acidosis with hyperkalemia and hyponatremia -> aldosterone deficiency->
addison's disease -> autoimmune vs. TB vs. hemorrhage vs. met cancer?
2821 Internal Medicine Electrolytes seizure -> chem panel 2 hours after. has lactic acidosis resolved?????
2821 Internal Medicine Electrolytes seizures -> muscles release lactic acid -> Anion Gap METABOLIC ACIDOSIS -> repeat labs in 2
hours
2837 Internal Medicine ID MYYYY AMINOGLYCOSIDE (GENTAMICIN, TOBRAMYCIN..........) -> MY EAR HAIR CELLS
A-DYING
2842 Internal Medicine ENT AERD (aspirin exacerbated respiratory disease) after NSAIDS is associated with nasal polyps.
2858 Internal Medicine Ophthalmology chalazion just chills there. vs. hordeolum hurts. vs. dacryocystitis (infected lacrimal sac) needs
antibiotics.
2877 Internal Medicine Hem&Onc iINCREASED TIBC microcytic anemia -> IRON DEF
2880 Internal Medicine Hem&Onc cirrhosis, bronze diabetes, dilated heart failure -> AR hemochromatosis -> genetic testing dx;
serial phelbotomy trx
2885 Internal Medicine Hem&Onc low leukocyte alkaline phosphatase (cells fucked up and not making enzyme)-> CML vs. high w/
PV or leukemoid reaction/ infection
2888 Internal Medicine Hem&Onc Smudge the CLLs
2889 Internal Medicine Hem&Onc back pain with anemia-> multiple myeloma?!?!?
2895 Internal Medicine Hepatology President Wilson on the copper penny-> dx liver biopsy + ceruloplasmin levels in blood; trx:
chelators, zinc, transplant
2901 Internal Medicine GIT
Antibiotics before LP vs. Antibiotics after paracentesis!!! ** high SAAC (serum albumin- ascites albumin) > 1.1 -> portal htn/ liver problem/ sbp. -> probs just need antibx if bacterial peritonitis is SECONDARY (from ruptured appendicitis for example) -> you'd see MULTIPLE types of bacteria, sUPER LOW GLUCOSE, SUPER HIGH LDH & PRTN -> get IMAGING and CONSULT SURGERY
2920 Internal Medicine GIT PBC is in WOMEN. vs. PSC associated with UC. (dx: cholangiogram and liver biopsy)
2924 Internal Medicine Hepatology Bodgan the Jew has Dubin-Johnson syndrome. Asymptomatic but shockingly black. Conjugated
hyperbilirubinemia. Rotor similiar but normal color.
2924 Internal Medicine Hepatology CONJUGATED hyperbili -> DJ Rotor!!! (Dubin-J - guiness colored liver), (Rotor-lacks color) vs.
UNconjugated hyperbili -> Gilbert (gentle) or Crigler-Najjar (this is the EVIL one, need transplant)
2934 Internal Medicine GIT ACUTE PANCREATITIS DIAGNOSIS: (2/3) -PAIN RADIATING TO BACK -ENZYMES 3X
-IMAGING (CT CONTRAST OR U/S) SHOWING ENLARGED PANCREAS
2936 Internal Medicine GIT PT (11-15) - teens PTT (25-40) - middle aged
2938 Internal Medicine Hepatology neuropsych sx and basal ganglia -> slit lamp that shit and get ceruloplasmin levels for WILSON'S
DISEASE
2950 Internal Medicine Hepatology "only people who wear lipstick get PBC. how did you get it??"
2953 Internal Medicine Hepatology hypokalemia/diuretic use -> ammonium (NH4+ -> NH3 which crosses BBB) ->hepatic
encephalopathy -> replace potassium + albumin
2961 Internal Medicine Hepatology hep B trx (even if decompensated cirrhosis)-> entecavir or tenofovir
2968 Internal Medicine Hepatology cutie amoeba protozoas! -> bloody diarrhea but only get 1 liver cyst and trx is metronidazole.
2977 Internal Medicine GIT dark urine/ + urine bili -> conjugated -> rotor's syndrome -> no trx
2986 Internal Medicine Hepatology HEP B is NBD. 90% recover some -> chronic. somse -> fulminant (encephalopathy within 8weeks
of acute liver failure) -> need transplant!!!
2995 Internal Medicine ID hilar nodes-> sarcoidosis, histoplasmosis (histo in ohio)
2995 Internal Medicine ID ANY TIME THEY GIVE YOU A LOCATION -> PAY SOME FUCKING ATTENTION TO ENDEMIC
DISEASES. TB looks like histo and blasto and sarcoidosis!
3011 Internal Medicine ID human or dog bites-> amoxi-clav (d-augmentin)
3012 Internal Medicine ID acute infective endocarditis -> 3 blood cultures, then empiric antibx. vs. subacute -3 blood cultures
spaced further apart + tailored antibx once cultures back
3014 Internal Medicine ID healthcare associated endocarditis -> staph vs. community-acquired -> strep
3021 Internal Medicine Respiratory pleural plaques if b/l -> likely due to asbestosis vs. if unilateral -> mesothelioma
3024 Internal Medicine Respiratory asthma presenting in adulthood or after lying down -> GERD
3029 Internal Medicine Respiratory Pneumonia in same location -> bronchogenic CA?? -> CT +/- bx
3042 Internal Medicine Respiratory pulse ox (O2 sat) < 88%, abg Pa02<55%, hematocrit >55% -> start OXYGEN trx
3062 Internal Medicine Hem&Onc
ankyrin scaffolding protein on RBC fucked up -> AD hereditary spherocytosis -> increased osmotic fragiliility on acidified glyceorl lysis test and abnormal binding test. coombs test negative-> folate, transfusions, splenectomy or else pigment gallstones + aplastic crises
3069 Internal Medicine Cardiology arthymmia from WPW -> IV procainamide or cardioversion (AV nodal blockers like BB, CCB,
adenosine, digoxin will send them into VFib!!!!)
3083 Internal Medicine Endocrinology constipation -> hyper-ca?? -> hyper- vitamin D???
3083 Internal Medicine Endocrinology FAD DIET -> VIT D TOX -> HYPERCALCEMIA
3085 Internal Medicine Electrolytes orthostatic hypotension with loss of Na+ and K+ in urine -> DIURETIC ABUSE????!?!?!?
3086 Internal Medicine GIT 4 mos -> folate def 4yrs -> b12 def
3090 Internal Medicine Cardiology Young ppl with chest pain -> AS from bicuspid aortic valve?!?!?!??! vs. HCM
3096 Internal Medicine Cardiology atrial tach (from increased ectopy) + AV block (increased vagal tone) -> digitalis TOXICITY
3099 Internal Medicine Endocrinology Hyperventilation -> resp alkalosis-> hypocalcemia (more bound to albumin, less free) ->
paresthesias, spasm
3105 Internal Medicine ID ALL TRANSPLANT pts need TMP-SMX to prevent PCP (pneumocystis pneumonia).
3131 Internal Medicine ID EBV -> Monospot dx (My one spot Bar). ABs against EBV can attack RBCs and plts-> coombs test
positive hemolytic anemia
3149 Internal Medicine Rheumatology synovial fluid analysis to distinguish: septic arthritis vs. gout vs. pseudogout.
3150 Internal Medicine Rheumatology gout PREVENTION-> allopurinol and probenecid
3150 Internal Medicine Rheumatology Prevent gout with probenecid & alloPurinol
3153 Internal Medicine Rheumatology suspicious joint fluid -> inflammatory vs. outrageous joing fluid -> septic. (purulent arthritis in
person having sex -> GONORREA until proven otherwise)
3157 Internal Medicine Rheumatology exertion -> exacerbates vascular claudication vs. posture (extension)-> exacerbates neurogenic
claudication
3161 Internal Medicine Poisoning METHANOL (anti-freeze) MESSES WIth YOUR VISION. vs. ETHYLENE (sweet radiator fluid)
EFFS UP YOUR KIDNEYS. *trx- fomepizole or ethanol. B1, B6, Folate
3161 Internal Medicine Poisoning IF THEY GIVE YOU A CHEM PANEL -> DO YOU THINK YOU NEED TO CALCULATE AN ANION
GAP?!?!?!?!?
3168 Internal Medicine Rheumatology diagnose rotator cuff tendinitis -> improvement with lidocaine!!
3173 Internal Medicine Rheumatology Hydroxychloroquine cleans out your (retina)-screen
3203 Internal Medicine Rheumatology different pathophysiologies for CTS.
3208 Internal Medicine Rheumatology dermatomyositis -> cancer????
3211 Internal Medicine Rheumatology pain with flexion, SLR (also flexing)-> pressure on anterior herniation -> HERNIATED DISK. vs.
pain with extension -> spinal facet problem -> SPINAL STENOSIS.
3230 Internal Medicine Endocrinology young person w/ HTN and diuretic-induced hypo-k -> PRIMARY HYPERALDOSTERONISM????
-> morning aldosterone: renin >20, and plasma aldos >15
3231 Internal Medicine Endocrinology aldosterone:renin over 20 -> 1* HYPERALDOSTERONISM -> CT and cut adrenal tumor out or
aldosterone antags
3245 Internal Medicine ID immunocompromised or old -> vanc + amp + cephalosporin for bacterial meningitis (amp gets
listeria)
3246 Internal Medicine ID tb prophylaxis -> 9 months isoniazid + B6 +liver fx tests vs. active, sx tb treatment -> combo drug
regimen
3248 Internal Medicine ID bloody diarrhea -> EHEC, Shigella, or Campylobacter
3256 Internal Medicine ID PCN allergic pt with syphilis -> doxy unless pregnant
3261 Internal Medicine ID Dirty (maculopapular rash) hands and soles -> syphilis
3263 Internal Medicine ID erysipelas -> group A strep
3266 Internal Medicine ID rubella (rapidly spreading) + joint problems or postinfectious encephalitis vs. measles (migrates
over days)
3267 Internal Medicine ID eosinophils <1% normally
3267 Internal Medicine ID Eosinophils < 3%
3317 Internal Medicine Rheumatology Osteoarthritis morning stiffness is ONLY 30 min or less. Vs. rheumatoid/inflammatory is really long.
3449 Internal Medicine ENT ENDOlymph in INNER ear -> menIERE's
3462 Internal Medicine Neurology transient arm weakness -> ACS? MS?
3483 Internal Medicine Endocrinology hypercholesterol/TG -> make sure no hypothyroidism before prescribing statins!
3484 Internal Medicine Endocrinology
you DONT need to FNA everyone with a fucking thyroid nodule!! only those with cancer risk factors or suspicious U/S findings or normal/high TSH. Low TSH -> scan -> if hot nodule most likely benign so just treat for hyperthyroidism; if cold nodule -> FNA that shit too.
3489 Internal Medicine Endocrinology vit D deficiency -> decreased calcium + phosphate absorbtion -> PTH -> bone resorption and
lower phosphate-> bone pain and osteomalacia
3490 Internal Medicine Endocrinology vit D deficiency -> decreased Ca and Phos absorption -> osteomalacia, secondary
hyperparathyroidism
3492 Internal Medicine Endocrinology bromocriptine, cabergoline -> DA AGONISTS for prolactinomas before surgery.
3493 Internal Medicine Endocrinology functioning pituitary adenoma -> prolactin >200 vs. nonfunctionig -> inert substantces +
compression effects (decreased TSH) *hypothyroidism ddx
3496 Internal Medicine Endocrinology anti-TPO ABs -> high risk Hashimoto's
3498 Internal Medicine Endocrinology Papillary thyroid cancer is most Popular. Radiation, family hx risk factors. Best prognosis.
3498 Internal Medicine Endocrinology Carcinoma-> lymphatics (except HCC, rcc, follicular, choriocarcinoma) Vs. Sarcoma -> blood
(connective tissue)
3499 Internal Medicine Endocrinology if i had to choose a thyroid cancer it would be PAPILLARY with PSAMMOMA bodies.
unencapsulated but FUCKING FANTASTIC prognosis even with mets!! :)
3499 Internal Medicine Endocrinology You want to see psamomma bodies -> papillary thyroid cancer good prognosis :]
3502 Internal Medicine GIT air in thorax -> eso perf -> gastrographin (barium inflammatory) vs. blood in thorax -> aortic
dissection
3506 Internal Medicine Cardiology restrictive lung disease -> NO AMIODARONE vs. obstructive lung disease -> NO BETA BLOCKERS
3518 Internal Medicine Endocrinology increased alk phos + mixed lytic/blastic lesions + hat size + secondary aosteoarthritis -> paget's
disease -> bone scan + bisphosphates if sx
3520 Internal Medicine Endocrinology MEN 1 -> 3Ps (pit, pancreas, PTH) vs. MEN 2a -> PTH, medullary thryoid cancer, adrenal pheo
vs. MEN 2b -> marfanoid and mucosal stuff, medullary thyroid cancer, adrenal pheo
3526 Internal Medicine Cardiology warmth/swelling/tenderness -> venous thrombosis (HIT) vs. lose pulses -> arterial clot (LV
thrombus after MI, LA thrombus from AFib, aortic atherosclerosis)
3561 Internal Medicine ID ANaerobic gram+ branching in face with sulfure granules and draining sinuses -> actinomyces ->
PCN vs. aerobic gram+ branching -> nocardia -> Bactrim
3585 Internal Medicine GIT Pain or anorexia w/ jaundice -> obstruction -> U/S for biliary obstruction/dilation vs. without
jaundice -> CT w/ contrast
3619 Internal Medicine Neurology migraine headache -> COMPAZINE(prochlorperazine) +/- ketoralac *metoclopramide 2nd line
*sumatriptan only good for prophylaxis
3635 Internal Medicine Cardiology pericaridial scarring (kussmaul's sign, sharp x and y descents-imparied relaxation, pericardial
knock, diastolic dysfunction)-> 2/2 viruses/radiation/surgery in US vs. TB in developing countries
3637 Internal Medicine Neurology pseudotumor -> bridging therapy (LP, steroids) + then ACETAZOLAMIDE (decreases actual CSF
production)
3648 Internal Medicine Genitourinary acute renal failure -> hyperkalemia, brady -> IV calcium gluconate to protect heart membranes
3680 Internal Medicine Hem&Onc back pain worse lying down -> cord compression vs. improved with recumbency ->msk
3693 Internal Medicine Genitourinary nitrites in urine (just like in smoked meats you eat) -> enterobacteria vs. LEUK esterase -> pyuria
(bacterial infection)
3698 Internal Medicine Cardiology
no QRS -> VF -> first debibrillator (CPR if unwitnessed or >5 min) -> then epinephrine/Q3min while CPR ongoing -> debrillator again-> antiarrhythmics (amiodarone, lidocaine, magnesium) if warranted.
3717 Internal Medicine Respiratory high suspicion PE in unstable pt-> IV heparin, don't wait for CTA
3729 Internal Medicine Endocrinology polyuria w/: -high glucose -> DM. -concentrated urine -> DI (central ro renal resistance). -dilute
urine -> polydipsia
3738 Internal Medicine Neurology dominant (L) frontal lobe -> broca's aphasia, contralateral weakness, look to lesion
3778 Internal Medicine Rheumatology DIURETICS MAKE GOUT WORSE!!!!!!!!! diuretics -> hypovolemia -> increased uric acid levels
3829 Internal Medicine Cardiology PVCs: -> nothing if asymptomatic -> BB -> amiodarone
3863 Internal Medicine
Preventive Medicine
50-74 women -> 2 boobs Q2 years until you're too fucking old. 21-65 women -> 3 hole area check Q3 years. 65+ -> DEXA
3873 Internal Medicine ID MMR ok in AIDs if CD4+ >200
3874 Internal Medicine Respiratory hoarse voice/persistent cough with afib and elevated left main bronchus-> left atrial
enlargement?? -> MS from rheumatic fever???
3890 Internal Medicine GIT bronze diabetes-> hemochromatosis!!!! (high ferritin and high transferrin saturation)
3892 Internal Medicine ID when you're 65 years old -> PCV13, then PPSV23 or just PPSV23 if you're comorbidy
3895 Internal Medicine Genitourinary eating protein bars BAD -> increased Ca2+ kidney stones.
3918 Internal Medicine GIT types of polyps: hyperplastic-nbd. vs. hamartomatous-nbd. vs. adenoma-small risk premalignant
(increased if sessile (structurally) or villous (histologically)). **Villous Villian Adenoma!!!!!**
3930 Internal Medicine Hem&Onc alcoholics can get folate deficiency in four weeks!
3936 Internal Medicine GIT NSAIDs -> GI bleeding -> iron def anemia
3945 Internal Medicine Cardiology nitrates -> dilate veins -> decrease preload -> decrease O2 requirement of heart
3951 Internal Medicine Genitourinary
nosebleeds, bruising, all sorts of bleeding during chronic renal failure -> due to platelet dysfunction (BT prolonged, but everything else normal) -> give DESMOPRESSIN (increases vWF release). DESMOPRESSIN FOR DAT FUCKING PLATELET DYSFUNCTION.
3958 Internal Medicine Cardiology dehydrated?? -> what's the BUN/Cr ?????? (>20 is very SENSITIVE but not specific for
hypovolemia)
3958 Internal Medicine Cardiology drop in 20/10 from supine to standing-> orthostatic hypotension 2/2 volume depletion (BUN/Cr
>20) OR baroreceptor sensitivity problem
3976 Internal Medicine Endocrinology Bb -> unoppposed alpha -> increases bp in cocaine tox and pheo
3977 Internal Medicine Cardiology severe HTN -> hypertensive urgency vs. severe HTN + papilledema/retinal bleed-> malignant htn
vs. severe HTN + cerebral edema/neuro sx -> hypertensive encephalopathy
3979 Internal Medicine Cardiology uremia ( increased BUN) -> pericarditis without EKG changes.
3987 Internal Medicine Genitourinary acyclovir -> not very soluble in urine -> crystal induced acute kidiney injury!!! -> give lots of FLUIDS
3994 Internal Medicine Cardiology old people -> lose elasticity -> increased systolic bp -> widened pulse pressure -> give anti-htn
med
4001 Internal Medicine Biostatistics RANDOMIZE to control for CONFOUNDING.
4003 Internal Medicine Cardiology wide pulse pressure-> decreased elasticity, AVM, AR vs. narrow pulse pressure -> AS,
tamponade, blood loss
4007 Internal Medicine Genitourinary chronic analgesic abuse -> papillary necrosis + tubuloinsterstitial nephritis (polyuria, sterile
pyuria/WBCs)
4024 Internal Medicine Respiratory pneumonia trx; outpt healthy-azithro vs. outpt unhealthy-levo vs. inpt/ICU- levo OR vanc+ zosyn +
levo OR CTX + azithro.
4027 Internal Medicine Genitourinary
stones invisible to X-ray: uric acid, xanthine, or super small calcium stones (<3mm). or maybe there's a blood clot or tumor!! Uric acid stone -> alkalinize urine w/ k-citrate (Urocit-K), low purine diet vs. calcium stones -> HCTZ (loops lose calcium) vs. xanthine stone (genetic)-> low purine diet vs. cysteine (genetic) or struvite (urease infection) stones -> staghorn -> surgery
4037 Internal Medicine Hem&Onc isoniazid -> B6 def -> sideroblastic anemia (microcytic/hypochromic anemia with increased iron,
decreased TIBC)
4040 Internal Medicine Respiratory Only intubate if face-mask fails (unstable, pH <7.1, )
4048 Internal Medicine Respiratory any sort of problem or change in health status-> theophylline toxicity?!?!?!??!?!?
4053 Internal Medicine Respiratory MORE PROTEIN AND LDH IN PLEURAL FLUID THAN SERUM + ACIDIC PH-> EXUDATE
(INFECTION, MALIGNANCY, INFLAMMATION, PE)
4054 Internal Medicine Cardiology coronary steal- tax cuts for the rich
4057 Internal Medicine ID cat scratch gram negative bartonella -> Z-pack
4061 Internal Medicine Cardiology
heart problems after virus (coxsackievirus)-> DILATED CARDIOMYOPATHY -> systolic dysfunction. vs. sudden cardiac death -> asymmetric septal hypertrophy vs. chronic pressure overload (HTN, AS)-> concentric hypertrophy vs. chronic volume overload (valvular regurg) -> eccentric hypertrophy
4068 Internal Medicine Cardiology amiodarone, lidocaine for vtach
4073 Internal Medicine Respiratory effusion with a low pH -> probs an empyema -> put in a chest tube (thoracostomy)
4078 Internal Medicine Rheumatology positive straight leg test & radiating pain -> HERNIATED DISK
4082 Internal Medicine Endocrinology
Low Calcium? 1. Check albumin-> For every decrease in albumin by 1, calcium falls 0.8. 2. Check mag (alc-> low mag-> PTH resistance -> low Ca) 3. Check PTH (if low -> hypoparathyroidism vs. if high -> resistance, vit D def, inflammation)
4083 Internal Medicine Rheumatology
radicular pain + SLT -> herniated disk vs. pain worse with extension + better with shopping cart flexion -> stpinal stenosis vs. point tenderness after injury + normal neuro + osteooporosis hx -> vertebral compression fracture
4091 Internal Medicine Dermatology cone acne -> topical retinoids vs. any other type of acne -> 1.topical antibx 2. oral antibx 3. oral
retinoids
4099 Internal Medicine Ophthalmology Herpes (HSV) HURTS. even in the eye. CMV doesn't.
4120 Internal Medicine ID recent UTI/infection + FOCAL back pain -> osteomyelitis? -> esr/crp, X-rays -> if X-ray normal, get
MRI then biopsy
4123 Internal Medicine Rheumatology smoking hx -> cancer -> paraneoplastic syndromes -> MG, Lambert eaten, dermatomyositis
(gottron's papules, heliotrope rash..confirm with muscle bx)
4127 Internal Medicine Cardiology chronic angina -> BB. (+/-CCB) vs. acute angina -> nitrates.
4133 Internal Medicine Cardiology hepatojugular/abdominaojugular reflux -> rise in jvp w/ compression of abdomen -> means you/re
RV is failing
4139 Internal Medicine Neurology seizure in someone with fever and acting strangely -> HSV-1 encephalitis?!?! -> LP and PCR the
CSF
4147 Internal Medicine Hem&Onc Folate supplementation for phenytoin, tmp, methotrexate!
4150 Internal Medicine GIT inflammation, infection -> INCREASE in platelets (want to stick up/contain disease)
4161 Internal Medicine Endocrinology fractured penis -> venous ED (PENIS IS VENOUS) vs. fractured pelvis -> neurogenic ED
4163 Internal Medicine ID endocarditis in IV druggie -> R sided vs. endocarditis in heart mumur hx pt (mitral valve
problem)-> L sided
4206 Internal Medicine Neurology hemi-neglect syndrome -> right (non-dominant) parietal lobe
4216 Internal Medicine Electrolytes TRANSFUSIONS during surgery -> citrate binding -> HYPOCALCEMIA -> muscle cramps,
hyperactive DTR.. *hypomagnesemia -> PTH resistance -> mimics hypocalcemia
4228 Internal Medicine Endocrinology parasympa lets you pee (detrusor contracts, internal sphincter relaxes), so a neurogenic bladder
-> overflow incontinence (high post-void volume, dribbling, poor stream)
4233 Internal Medicine Respiratory hotels, cruise ships -> Legionella gram negative rod -> hyponatremia, brady with fever, hepatitis,
confusion, GI problems, pneumonia -> urine antigen testing, macrolide or fluoroquinolone
4236 Internal Medicine Electrolytes vomit = HCl + KCl -> hypochloremic hypokalemia with elevated bicarb
4257 Internal Medicine ID nail puncture in tennis shoes (mike burnim) -> PSEUDOMONAS
4266 Internal Medicine Genitourinary FACE OR ANKLE EDEMA -> LIKE YUJ!!! ..NEPHROTIC SYNDROME? -> HYPERCOAGULABLE
STATE. BEWARE RENAL VEIN THROMBOSIS.
4268 Internal Medicine Neurology
contralat sensory/motor deficit, conjugate eye deviation, homonymous hemianopia, aphasia/hemineglect (cortical signs) -> MCA occlusion vs. pure M or pure S or lacunar syndrome -> infarct in BG or subcortical white matter
4278 Internal Medicine Hepatology normal liver (<12cm) less than a dozen everything reversible (steatosis, alcoholic hepatitis, early
fibrosis) ..except cirrhosis! Respect SIR-cirrhosis.
4282 Internal Medicine ENT cipro gets pseudo!! (as does piptaz, aminoglycosides, penams, aztreonam)
4282 Internal Medicine ENT pseudo -> cipro, zosyn (pip-taz), AGs, pens CTX (3) none but CefTazidime(3) and cefepime(4) do
4297 Internal Medicine Respiratory 25% COPD pts -> Cor pulmonale -> edema, hepatomegaly/ascites, exertional sx, distant heart
sounds, increased jvp, tricuspid regurg. *MR, TR, VSD, AS -> all holo-systolic mumur
4303 Internal Medicine GIT Upper GI
4304 Internal Medicine Endocrinology hyperCa + hyperPTH ->primary hyperparathyroidism. vs. hyperCa + hypoPTH-> badness (cancer,
sarcoid, vit D tox)
4307 Internal Medicine Endocrinology hyperthyroid -> bone loss + afib complications
4309 Internal Medicine Endocrinology
sitting for long periods of time -> BONES GET RESORBED!!!!! -> hypercalceima. especially if young, paget's disease, or chronic renal insuff ****give bisphosphonates and hydrate **albumin = 4, calcium =10; LOW ALBUMIN -> LOW CALCIUM; for every 1 decrease in albumin, -.8 for calcium
4309 Internal Medicine Endocrinology 4 weeks not moving -> clasts absorb bone (don't use it, you lose it). *prevent with H20 and
bisphosphonates.
4316 Internal Medicine Hem&Onc decreased plts? -> HIT 2 ?!?!?!?!?!!?!??!?!?!
4331 Internal Medicine Hem&Onc no G6PD -> hb denatures into Heinz bodies- > bite cells
4338 Internal Medicine Hem&Onc PLATELETS PAYS THE DINNER BILL 150-400K. *LOW PLATELETS + ANEMIA + INCREASED
BILI -> TTP? -> PERIPHERAL BLOOD SMEAR FOR SCHISTOCYTES
4339 Internal Medicine Hem&Onc fragmented RBCs + low platelets (MAHA), bloody diarrhea, HTN, neuro findings, abdominal pain->
idiopathic TTP-HUS??? -> Plasmapheresis or pt will DIE (monitor plts and LDH)
4339 Internal Medicine Hem&Onc Random MAHA -> idiopathic ttp-hus -> plasmapheresis to take out auto-AB or DiE
4351 Internal Medicine Hem&Onc nodes <1cm -> nbd, just watch it.
4370 Internal Medicine Rheumatology
LOWER BACK PAIN: msk- spinal stenosis-shopping cart sign, slipped disk-radiating pain, fracture, mechanical- strain/spasm/degen. vs. inflamm- worse with rest, gradual, hla-b vs. malig- old, weight loss vs. infectious-fever, focal, IVDU, recent infection
4371 Internal Medicine Rheumatology chronic inflammation/stress -> increased platelets (reactive thrombocytosis) to help stick germs to
wbcs
4385 Internal Medicine GIT
just fibrinogen, VWF, or F8 deficiency -> Cryo vs. clotting factor def, DIC, or overdose warfarin -> FFP (ALL clotting facotrs) vs. platelets <50,000 in bleeding pt -> platelets vs. hg<9 in sx pt or hg<7 -> packed RBC
4387 Internal Medicine Respiratory
decreased breath sounds -> pleural effusion(dullness to percussion, egophony) or pneumothorax(hyperresonnant to percussion) or emphysema (hyperresonant, vesicular breathsounds) vs. bronchial breath sounds (louder, esp expiratory), dullness to percussion, egophony, crackles -> consolidation vs. vesicular breath sounds/crackles at end inspiration -> interstitial lung disease vs. no breath sounds -> COLLAPSED airway
4393 Internal Medicine Neurology GI loss, anorexia, hyperaldosteronism, diuretics-> hypokalemia -> flattened T waves, U waves, ST
depression, premature ventricular beats
4396 Internal Medicine Cardiology pleuritic chest pain -> PE????? vs. pericarditis????
4401 Internal Medicine Neurology Ach -> excitatory in skeletal muscle but inhibitory in heart muscle! so... anticholinergic -> dilated
vessels/flushing but tachy (loss of inhibition!)
4419 Internal Medicine Electrolytes steriods -> hypokalemia
4422 Internal Medicine Electrolytes it's easier to sweep potassium under the rug than get rid of it! (insulin + glucose works in 15
minutes!) fast but transient effect.
4425 Internal Medicine Electrolytes hypernatremia -> DIABETES INSIPIDUS ??? (central or peripheral)
4428 Internal Medicine Electrolytes For paralytic, SUCC SUCKS. ROC ROCKS. Succ-> hyperkalemia, brady, increased IOP. quick
recovery (10min) vs. Roc-> nothing too bad. just slower recovery but reversible.
4440 Internal Medicine Hem&Onc thalassemia -> hemoglobin chain weird but normal # RBCs and normal RDW (range of
size)...unlike iron deficieny
4445 Internal Medicine Cardiology
2nd heart sounds: ASD -> fixed split. ASD IS FIXED PROBLEM. vs. Right heart prb (PS, RBBB) -> Wide split. RIGHT IS WIDE. vs. Left heart prb (AS, LBBB) -> Paradoxical split. LEFT IS LOONY. ************ low bp, muffled sounds, distended vv -> Beck's triad -> TAMPONADE ************ tenneSEE -> S3 -> CHF vs. KEN-tucky -> stiff ventricles/ AS/HCM -> S4
4449 Internal Medicine Rheumatology 1/2 PV pts -> increased uric acid turnover -> gout
4450 Internal Medicine Cardiology SVT -> try some vagal stuff ( valsalva, carotid sinus massage, ice-water) or adenosine ->
decreaes conduction through AV node; break out of reentry
4459 Internal Medicine Cardiology increased pulse pressure -> decreased elasticity b/c you old vs. AV fistula???
4466 Internal Medicine Hem&Onc CRAB + paraprotein gap -> Multiple Myeloma
4469 Internal Medicine Cardiology LONE AF PEOPLE (CHADS VASC 0, < 65 YEARS, MALE, AND NO RISK FACTORS)-> NO
WARFARIN OR ORAL ANTICOAGULANTS NEEDED
4470 Internal Medicine ID + TB test if: >5mm induration for immunosuppressed people. >10mm induration for me. >15mm
for normal people.
4473 Internal Medicine Cardiology acetaminophens + NSAIDS -> BLEEDY
4474 Internal Medicine Genitourinary RIGHT kidney in ADPKD easier to palpate b/c LOWER.
4475 Internal Medicine ID
pneumo vaccine 13 for those more at risk: kids, elderly, and immunocompromised. vs. pneumo vaccine 23 for smoking/alc/less than healthy adults (smokers, DM, lung/liver/heart prb). vs. Sequential 13 + 23 for VERY HIGH RISK/DYING adults.
4477 Internal Medicine
Preventive Medicine Td booster every 10 years + Tdap every pregnancy.
4482 Internal Medicine Neurology deep lacunar strokes usually THROMBOTIC (embolism usually proximal; too big to make it
deeper), and may not see on CT b/c so fucking small.
4484 Internal Medicine Cardiology pulsus parvus et tardus -> AS vs. diastolic mumur -> AR
4487 Internal Medicine Poisoning anticholinergic effects + seizures + long QRS -> TCA OD -> Bicarb to treat hypotension
4487 Internal Medicine Poisoning tCA od -> biCArb
4489 Internal Medicine Respiratory Bicarb ~25 C02 ~35
4490 Internal Medicine Genitourinary Cr > 1.5 -> renal insufficiency -> non-ionic contrast CT
4513 Internal Medicine Neurology brain abscess from sinus infection -> STREP viridans or anaerobes/bacteroides vs. abscess from
surgery/trauma -> STAPH
4514 Internal Medicine Endocrinology DKA-> osmotic diuresis causes K+ loss, but redistribution from acidemia creates appearance of
hyperkalemia.
4516 Internal Medicine Ophthalmology infection/stress -> increased cortisol/cats -> insulin fucked up -> hyperglycemia -> osmotic
diuresis, ams, blurry vision (nonketotic hyperglycemia in DM2)
4522 Internal Medicine Poisoning neuroleptic malignant syndrome -> Dantrolene + Dopamine agonists (bromocriptine, amantadine)
4524 Internal Medicine Cardiology
radiation, TB, virus/idiopathic -> scarred pericardial sac-> CONSTRICTIVE PERICARDITIS, RHF -> hepatojug reflex, kussmaul's sign (JVP doesn't change with breath), pulsus paradoxus,pericardial knock (mid-diastolic), pericardial thickening/calcification
4524 Internal Medicine Cardiology Kussmaul- Inhaul -> paradox rise in neck veins (where you kiss) 2/2 right heart filling prb
4535 Internal Medicine Electrolytes Increased BUN -> GI BLEED?????????? (blood proteins get broken down to urea)
4536 Internal Medicine Respiratory If ABG shows pO2 really high: 1. Slowly decrease FiO2 to non-toxic levels (<60%). 21% is normal
sea level. 2. Increarse PEEP to maintain oxygenation GOAL : ABG pO2> 60
4564 Internal Medicine Rheumatology short-lived morning stiffness -> OA vs. lingering morning stiffness -> inflammatory
4566 Internal Medicine Respiratory
coughing up a little blood with no fever/concern for pneumonia -> probably ACUTE BRONCHITIS 2/2 virus, NBD. been there, done that. yellowish sputum can be from epithelial sloughing too, not neccessarily an infection.
4568 Internal Medicine Respiratory untreated pneumonia -> pus in pleural cavity (EMPYEMA) -> drainage and antibx
4572 Internal Medicine Rheumatology morning stiffness >1hr + systemic symptoms ->RA-> inflammation + RA treatment (steroids) ->
osteoporosis -> give bisphosphonates to kill osteoclasts!
4575 Internal Medicine Respiratory ESR SHOULD BE <20!!!! <20. <20. <20.
4585 Internal Medicine Rheumatology Chronic Inflammation -> secondary amyloidosis
4586 Internal Medicine Rheumatology knee pain with crepitus, coolness, calm mornings (resolves within 30 min) and can be
monoarticular-> OA and not something inflammatory
4593 Internal Medicine Cardiology COPD, diseases of lung -> pulm HTN -> right heart failure -> hepatic congestion + peripheral
edema
4611 Internal Medicine ID bactrim in HIV pts for prevention of toxo reactivation and PCP
4616 Internal Medicine Cardiology THROMBOSIS ON HEPARIN -> HIT (nonimmune vs. immune)
4620 Internal Medicine Neurology early gait problems -> hydrocephalus vs. late gait problems -> alzheimer's
4627 Internal Medicine Endocrinology elevated alk phos but normal everything else -> PAGET disease of bone.
4631 Internal Medicine Respiratory any one of lights criteria met -> EXUDATIVE effusion -> pneumonia? cancer? inflammation?
4639 Internal Medicine Cardiology erectile dysfunction + skin problems + joint problems + liver problems + DM + dilated CM->
hemochromatosis!!
4651 Internal Medicine Neurology WET, WOBBLY, WACKY -> NPH
4671 Internal Medicine Hem&Onc ABO mismatch -> within ONE HOUR: DIC, renal failure, fever (acute hemolytic transfusion rxn)
4679 Internal Medicine Cardiology S3 in older people-> too much blood or filling too rapidly with blood -> heart failure, restritive
cardiomyopathy vs. S4 in younger people -> stiff ventricles, acute MI
4686 Internal Medicine Biostatistics cohort-pick group based on RISK FACTOR. estimate incidence (# new cases of disease), allows
calculation of Relative RISK.
4700 Internal Medicine Neurology ams -> thiamine before dextrose
4700 Internal Medicine Neurology eyes, lies, capsize -> wernicke encephalopathy -> thiamine B1 def
4703 Internal Medicine Neurology temp over 105 and AMS (w/ tachy, coagulopathic bleeding, renal failure, ARDS..) in workers in
humid weather -> EXERTIONAL heat stroke.
4707 Internal Medicine Cardiology HTN -> elevated LV diastolic pressure -> LA dilates-> AFib. anemia, hyperthroidism, beriberi,
paget's, av fistulas -> ventricles work harder but can't compensate -> high-output heart failure.
4714 Internal Medicine ID splenic abscess (fever, wbc, LUQ pain) -> infective endocarditis??
4718 Internal Medicine Respiratory O2 saturation goal in COPD exacerbation -> 90-94% !!!!! (if higher, risk hypercapnia/Co2 narcosis
from V/Q mismatch)
4725 Internal Medicine Cardiology (No pulse????) PEA or Asystole -> ACLS (CPR/2min, IV acess + pressors/4min!!!!) vs. Vfib or VT
with no pulse -> defibrillate vs. unstable Afib w/ RVR or symptomatic VT-> cardiovert
4742 Internal Medicine Cardiology
ASA or BB -> bronchoconstriction. *I'm depressed when I'm ischemic!! (ST depression -> ANGINA/ischemia) * acute dyspnea-> arrhythmia, broncoconstriction, CHF/hypervolemia, infection, aspiration, pleural effusion, PE, anxiety
4753 Internal Medicine Respiratory if increased protein OR LDH in pleural fluid -> EXUDATE.
4771 Internal Medicine Cardiology INCREASED PRESSURE IN PERICARDIAC SAC ( tamponade, copd, severe asthma) -> pulsus
paradoxus: deep breath-> more Q to RH-> less to LH -> exaggerated systolic bp drop.
4859 Internal Medicine Hem&Onc clot -> trx w/ heparin -> HIT 2?!?!?!? -> more clots!!!. how ironic.
4866 Internal Medicine Electrolytes metabolic alkalosis: -saline responsive/vomiting or volume depletion (retaining chloride) vs. -saline
resistant/mineracorticoid problem (peeing lots of chloride out)
4902 Internal Medicine ENT rinne: + if you can feel ringing on mastoid but can 't hear it when next to ear. * confirm with weber.
fork in forehead-> noise louder in ear with conductive prb/wax
4920 Internal Medicine Cardiology Skinny QRS -> SVT -> vagal manuevers/ IV adenoSine vs. Wide QRS -> VTach -> amiodaTone,
lidocaine
8823 Internal Medicine Psychiatry no circadian rhythm -> shift work sleep disorder (my life) vs. takes forever to fall asleep. night owl
schedule-> delayed sleep phase syndrome -> light/behavioral therapy
8876 Internal Medicine Endocrinology Calcium should be 8-10. Low calcium -> 1. Check mag. 2. Check PTH.
8901 Internal Medicine Endocrinology GI disease-> vit D def -> hypo-calcemia and hypo-phos -> increased PTH
8905 Internal Medicine Respiratory fev1 decreases in both obstructive and restrictive lung disease, but fev1/fvc < 70% -> Obstructive
8926 Internal Medicine Ophthalmology fixed, dilated pupil + hazy cornea -> acute angle-closure glaucoma vs. inflammed iris -> anterior
uveitis
8933 Internal Medicine Rheumatology yellow lighting bolts -> GOUT
10146 Internal Medicine Poisoning smoke inhalation -> hydroxocobalamin antidote for HCN poisoning
10287 Internal Medicine Electrolytes blood and protein and casts in urine -> GLOMERULEAR cause.
10301 Internal Medicine ID
SCREENING for HIV -> AG and AB combo test for early detection (before ABs made). if + -> CONFIRM w/ AB differentiation assay... if negative blood tests but you still think person high-risk -> plasma RNA testing
10767 Internal Medicine Cardiology malignant htn + scleroderma -> scleroderma renal cris ( schistocytes and thrombocytopenia on
smear)
10780 Internal Medicine Neurology Dystonia Akathisia Parkinsonism Tardive dyskinesia
10958 Internal Medicine Endocrinology HTN + tachy + fever + lid-lag -> THYROID STORM???!?!?
11067 Internal Medicine GIT PPIs -> C-diff!!! Shafik watch out!!
2344 Obstetrics & Gynecology OBGYN S. Aureus -> dicloxacillni, cephalexin vs. MRSA-> Bactrim, Clinda, Vanc
2388 Obstetrics & Gynecology OBGYN
no boobs = no estrogen. like i've got no estrogen. don't even need to measure my estrogen levels. say i've never gotten a period. 1. U/S -> if no uterues, get karyotype & testosterone vs. if uterus, get FSH (if increased-> peri prb get karyotype vs. if decreased-> central problem get MRI)
2398 Obstetrics & Gynecology OBGYN urethral hypermobilitly (weakened pelvic floor muscles)-> over 30* swab test angle -> stress
incontinence-> kegel then urethropexy
2405 Obstetrics & Gynecology OBGYN meredith would totally get an amniotic fluid embolism.
2407 Obstetrics & Gynecology OBGYN placenta rips off a little (placenta abruption) -> pain, increased uterine tone, increased freq
2411 Obstetrics & Gynecology OBGYN ectopic with bHCG 1500-6500 1. transVAGINAL U/S 2. if negative, serial bHCGs
2412 Obstetrics & Gynecology OBGYN turn try to turn baby until 37th week (3 week notice to self-fix)
2419 Obstetrics & Gynecology OBGYN PMS -> SSRIs
2523 Obstetrics & Gynecology OBGYN PAINLESS PREVIEW (bleeding). placenta previa.
2533 Obstetrics & Gynecology OBGYN placenta previa->> painless bleeding vs. vasa previa->> painless bleeding + fetus deteriorates/dies
2536 Obstetrics & Gynecology OBGYN dilated OS -> incomplete or inevitable abortion
2563 Obstetrics & Gynecology OBGYN RBC CASTS -> TRUE NEPHRITIS. not just protein loss from HTN/preeclampsia.
2567 Obstetrics & Gynecology OBGYN
increased AFP -> NT or abdominal wall defect or multiple gestation (increased levels of protein/protein spilling out of structural deformity!!!) vs. decreased AFP-> aneuploidies (your actual baby is fucked up chromosomally).
2568 Obstetrics & Gynecology OBGYN 2nd trimester quad screen/ 4 things: Hcg Inhibin AFP Estriol in down syndrome, high HI, low AE
2925 Obstetrics & Gynecology Hepatology PUPPP spares Palms (& soles & face) vs. intrahepatic cholestasis of pregnancy (dx of exclusion)
(itchy palms & soles, worse at night)
3110 Obstetrics & Gynecology OBGYN decreased fetal movements or high risk pregnancy -> NST (fetal heart rate: at least 2 accels of at
least 15 above baseline lasting at least 15 seconds?) -> if not, NOISE stimulation.
3116 Obstetrics & Gynecology OBGYN arrest of labor: >6 cm dilated with ruptured membranes but no change over 4 hours despite good
effort/contractions vs. no change over 6 hours despite weaker/inadequate contractions
3120 Obstetrics & Gynecology OBGYN
menorrhagia ddx: -bulky, boggy, globular, tender uterus -> adenomyosis vs. -pain with sex, infertility -> endometriosis vs. -postmenopausal or obese or nulliparity -> endometrial hyperplasia/cancer
3269 Obstetrics & Gynecology OBGYN for preterm labor: >34 weeks -> just floor it and deliver vs. 23-33 weeks -> steroids for lungs, mag
sulfate for neuro, +/- tocolytics vs. <23 weeks -> not viable
3273 Obstetrics & Gynecology OBGYN if fetus' kidneys fucked up-> gotta let it die
3337 Obstetrics & Gynecology OBGYN lochia: bloody, serous/pale, alba/white. foul-smelling-> endometritis, otherwise low-grade fever ok
3370 Obstetrics & Gynecology OBGYN during ovulatory phase, mucus CLEAR + THIN (stretches to 6 cm), more basic, ferns, vs. any
other time, mucus inhospitable (scant, thick, opaque)
3679 Obstetrics & Gynecology OBGYN pH >4.5 is increased for vagina -> BV or trich....(or both)
3745 Obstetrics & Gynecology OBGYN POSTERIOR vagina wall is where the penis goes (hpv 16,18, scc)
3868 Obstetrics & Gynecology OBGYN puberty before 8 years old -> precocious. advanced bone age. Central (high FSH,LH) vs.
peripheral-gonads/adrenal (low FSH, LH)
3869 Obstetrics & Gynecology OBGYN low amnioic fluid level, nuchal cord, cord proloapse -> cord compression -> variable decels -> if
RECURRENT, improve oxygenation, change mom's position, amnioinfusion
4124 Obstetrics & Gynecology Endocrinology pregnant -> INCREASED total, binding, AND free T3,4 -> negative feedback -> DECREASED TSH
4136 Obstetrics & Gynecology OBGYN menopausal or hyperthyroid? -High FSH vs. low TSH.
4148 Obstetrics & Gynecology OBGYN pregnant women- elevated alk phos. increased renal Q and gfr-> decreased serum BUN,
creatinine
4220 Obstetrics & Gynecology Endocrinology if i didn't get my period for 3 cycles..-> b-hCG for preg, prolactin for brain tumor, TSH for
hypothyroidism, FSH for premature ovarian failure
4221 Obstetrics & Gynecology OBGYN prolactin is inhibited by dopamine and stimulated by serotonoin and TRH.
4221 Obstetrics & Gynecology OBGYN Hypothyroid -> increased trh, tsh -> stimulates prolactin -> inhibits gnrh -> amenorrhea with
galactorrhea
4472 Obstetrics & Gynecology ID bacteria in urine in preggers -> not acceptable -> no bactrim, no cipro, nitrofurantoin, augmentin,
or cephalexin OK
4530 Obstetrics & Gynecology
Preventive Medicine All preggers need HIV, syphilis, and hep B screens for baby
4757 Obstetrics & Gynecology OBGYN 1st gen cephalosporins: cefazolin = ancef -> (Ancef Only IV) vs. cephalexin = keflex -> Eat keflex
on a kleenex. (oral available)
4758 Obstetrics & Gynecology OBGYN HGSIL on pap smear-> colposcopy to rule out invasive cervical cancer -> if negative, repeat 6 wks
after delivery
4759 Obstetrics & Gynecology OBGYN bHCG should DOUBLE/48 hrs if VIABLE. Slower rate if ectopic or nonviable. transvaginal U/S
1,500-2,000 -> you can see something
4767 Obstetrics & Gynecology OBGYN estrogen-> builds endometrium. withdrawal of progesterone from corpus luteum after ovulation ->
menses. if no ovulation, no progesterone, no real menses, just breakthrough bleeding.
4775 Obstetrics & Gynecology OBGYN <20 weeks -> spontaneous abortion vs >20 weeks -> intrauterine fetal demise -> autopsy to
prevent in future pregnancies
4779 Obstetrics & Gynecology OBGYN
new-onset htn (140/90) + proteinuria OR other end-organ damage AFTER 20 WEEKS -> pre-eclampsia!! risk factors: multiple gestation, nulliparity, DM, being old, CKD, previous SEVERE if >160/110, decreased plts, creatitine >1.1 or increasing, tarnsaminitis, pulm edema, new neuro sx
4779 Obstetrics & Gynecology OBGYN acute infection -> inhibits plts severe preelampsia -> " vs. chronic inflammation -> increase plts.
4781 Obstetrics & Gynecology OBGYN HELP ME REMEMBER HELLP SYNDROME!! severe preeclampsia: hemolysis, elevated liver
zymes, low plts
4782 Obstetrics & Gynecology OBGYN preeclampsia -> arteries spazz out -> increased afterload -> pulmonary edema -> diuretics,
oxygen, fluid restriction
4791 Obstetrics & Gynecology OBGYN Silent Syphilis (ulcer doesn't hurt) vs. chancroid - purulent ulcers with painful lymphadenopathy vs.
herpes -burning/itching then vesicles
4796 Obstetrics & Gynecology OBGYN VERTEX is NORMAL. head down dumbass.
4802 Obstetrics & Gynecology OBGYN spontaneous abortion (<20wks) with CLOSED CERVIX -> Missed or Threatened. Missed or
Threatened. Missed or Threatened.
8917 Obstetrics & Gynecology OBGYN Yimu may well clear her infection. 50% sexually active women get HPV within 3 years; 50% clear
within 2 years.
8962 Obstetrics & Gynecology OBGYN VEAL CHOP variable decel-cord compression/prolapse early decel-head compression accel- OK
late decel- placental insuff
10441 Obstetrics & Gynecology OBGYN chromosomal screening at 10-12 weeks -> cell-free fetal DNA, then confirm with CVS. vs. at 15-20
weeks -> amniocentesis2439 Pediatrics Pediatrics T wave inversion -> MI, myocarditis, myocardial contusion, digoxin tox
2445 Pediatrics Endocrinology Shitty AR Developmental Diseases w/ cherry-red macula: Niemann Pick- (spingomyelinase def) )areflexia, hepatosplenomegaly vs. Tay-Sachs- (B-hexs def) hyperreflexia
2450 Pediatrics Pediatrics lupus dx-> anti-SMITH and dsDNA. Check Ms. Smith's DNA for SLE.
2465 Pediatrics GIT
bilious vomiting -> NPO, NG decompression, IVF, & XRAY: -if free air or unstable - > SURGERY. -if dilated loops bowel -> CONTRAST ENEMA to differentiate MECONIUM ILEUS vs. HIRSCHSPRUNG. -if double bubble -> DUODENAL ATRESIA. -if NG tube misplaced -> UPPER GI SERIES for malrotation/volvulus.
2468 Pediatrics Pediatrics Edward the vampire (Trisomy 18) has a hole in his heart (VSD).2485 Pediatrics Pediatrics babies heal their clavicles in 1 week!!! amazing.
2513 Pediatrics Genitourinary don't get depressed with your toddler's potty-training -> try desmopressin!!! (risk hyponatremic seizures though..)
2758 Pediatrics Dermatology Eczema = atopic dermatitis
2867 Pediatrics Hem&Onc MOST leukemias in kids are ALL. lymphoblastic (increased immature forms of B and T cells) which are PAS, TdT+
3192 Pediatrics Pediatrics von gierke's: G6P -X> glucose. glycogen accumulates in liver, kidney....hypoglycemic seizures, doll-face
3196 Pediatrics Pediatrics X-linked agammaglobulinemia: most eXtreme (decreased B cells and decreased Ig) vs. Common variable: B cells fine, all common Ig decreased
3284 Pediatrics Hem&OncpainLESS lymph nodes -> lymphoma?!?!?!?!?!?!??! widened mediastinum on cxr may be lymphadenopathy!! decreased plts-> petechiae. decreased RBC -> pallow. >25% blasts on bone marrow bx diagnostic.
3284 Pediatrics Hem&Onc leukEMIA??? -> blood + BONE MARROW BIOPSY (>25% blasts) -> lymph node bx if bone marrow negative or if worried about lymphOMA.
3289 Pediatrics Respiratoryinspiratory stridor + dysphagia + drooling + tripoding + high fever + thumbprint sign on x-ray -> epliglottis from Hib or other bacteria -> trach them vs. inspiratory stridor + barky cough + steeple sign of x-ray-> croup -> nebulized epinephrine
3404 Pediatrics Pediatrics insidious hip pain in 6 yr old boy -> Legg calve perthes vs. 13 yr old boy-> scfe3442 Pediatrics Pediatrics meningitis + rash -> ADRENAL HEMORRHAGE.3459 Pediatrics Respiratory pO2 >75 (75 to pass the exam)
3543 Pediatrics Cardiology turner syndrome girls have grade-A problems (bicuspid Aortic valve, coarct of Aorta, Aortic root dilatation)
3546 Pediatrics Cardiology
standing (blood to LE), valsalva (blood to pelvis)-> decreased VR -> everything less except MVP and HCM (decreased heart mumur -> INNOCENT/PHYSIOLOGICAL MUMUR :) vs. leg raise/squats (exercise)-> blood to heart -> increased preload -> everything stronger except MVP, HCM
3550 Pediatrics Neurology NF1- 1 cafe au lait pour moi vs. NF2-Bilateral acoustic neuromas
3554 Pediatrics Pediatricsscrotal/abdominal pain + palpable purpura + joint pain + kidney prbs after URI = VASCULITIS?????? SAY IgA-mediated HENOCH-SCHONLEIN PURPURA ?!?!?! -> supportive, steroids
3577 Pediatrics ID septic arthritis -> tap joint, then give IV VANC -> then adjust antibiotics3640 Pediatrics ID sickle cell??-> you basically don't have a spleen -> PCN until at least age 5
3658 Pediatrics Pediatrics most common cancer in kid: LEUKEMIA (ALL) vs. most common SOLID cancer in kid: BRAIN TUMOR (astrocytoma-benign so not gbm, infratentorial)
3669 Pediatrics Pediatrics Don't want Duchenne's. GOLD STANDARD is GENETIC STUDIES.3688 Pediatrics Genitourinary babies with AN UTI -? U/S vs. babies wtih RECURRENT UTIs -> voiding cystourethrogram3713 Pediatrics Hem&Onc acute infection-> inhibits/decreases plt production vs. chronic inflammation-> increased plts3755 Pediatrics Pediatrics nontender blue patches in ethnic baby -> mongolian spot (congenital dermal melanocytosis)
3758 Pediatrics Pediatrics chlaymida in your baby's eye -> ORAL erythromycin (to get it out of their throat too) vs. gonorrehea in your baby's eye -> IV or IM CTX
3867 Pediatrics Endocrinology secondary sex characteristics are different!! adrenals make androgen-> (hair and body odor, incr DHEA> test) vs. ovaries make estrogen-> (big boobs)
3875 Pediatrics Endocrinology advanced bone age? -> someting is FUCKED up => check LH -> if High, central prb, if low (inhibited), peri prb.
3875 Pediatrics Endocrinology if bone age is advanced -> there is a peri or central PROBLEM. not idiopathic. look at LH-> if high central prb, if low (even with GnRH stimulaion) peri prb.
3924 Pediatrics Pediatrics headaches + weak legs -> COARCT, collaterals, rib notching 3924 Pediatrics Pediatrics Murmur everywhere over chest -> collaterals -> coarctation
3926 Pediatrics Pediatrics -fat in stool -> pancreatic enzyme deficiency -> CYSTIC FIBROSIS??? -not growing +recurrent URIs -> CYSTIC FIBROSIS????
3991 Pediatrics Cardiology Left axis deviation in newborn -> tricuspid valve atresia (wimpy right heart)
4038 Pediatrics Pediatrics high fever and acute onset bone pain -> osteomyelitis! vs. gradual pain with no fever -> avascular necrosis!!
4064 Pediatrics Pediatrics anterior slip/ step off-> spondylolis(SLIP)thesis
4183 Pediatrics GIT thickened (ion channel dysfx) meconium obstructing ileum -> meconium ileus -> CF? vs. normal meconium obstructing colon -> hirschsprung disease -> DOWN SYNDROME?
4260 Pediatrics Cardiology most common cyanotic heart prb in newborns-> TRANSPOSITION (single S2) -> PGE4271 Pediatrics Neurology VC + RV = TLC (capacity = sum) (VC= TV + IRV +ERV)4290 Pediatrics GIT gastroschisis- naked bowel. usually isolated defect plastic wrap that shit and surgery immediately.4302 Pediatrics Pediatrics angular cheilitis, normocytic anemia, seborrheic dermatitis -> riboflavin B2 def4317 Pediatrics ID Cats dogs humans bite -> daugmentin4823 Pediatrics Pediatrics obj permanence at 6 months. ...which leads to -> sep anxiety around 1 year
4845 Pediatrics ID ptosis-> heavy lids (horner's syndrome, mg) vs. prOPTosis/EX-ophtalmos -> eye bulging OUT (graves, cellulitis)
4847 Pediatrics Hem&Onc decreased plts + recurrent infections + eczema => WAS8772 Pediatrics Hem&Onc Onion-skin Ewing Vs. Sunburst osteoSarc2482 Psychiatry Psychiatry Conduct disorder for Kids. vs. Antisocial for Adults.2508 Psychiatry Psychiatry brief psychotic disorder (1 day-1 month) schizophreniform (1-6 months) schizophrenia (>6 months)
2510 Psychiatry PsychiatryMANIC episodes w/ or w/out depressive episode -> bipolar 1 vs. hypomanic episodes (not hospitalized, not impairing fx, no psychosis) + depressive episode -> bipolar 2 vs. hypomanic + depressive symptoms for at least 2 years -> cyclothymic disorder
2518 Psychiatry Psychiatry EPS -> usually from typical antipsychotics + risperidone. can change to clozapine but last resort due to agranulocytosis risk
2521 Psychiatry Psychiatry illness anxiety disorder/hypochondriac = fear of getting disease but NO SX vs. somatic symptom disorder = anxiety w/ physical SX > 6 months
3147 Psychiatry Psychiatry schizoid andrea. avoidant swetha.3147 Psychiatry Psychiatry avoidant swetha. schizoid andrea. AS. SA.3185 Psychiatry Psychiatry rich and single and genetics-> increased risk bipolar.3375 Psychiatry Psychiatry tourettes act psychotic -> trx antipsychotics3470 Psychiatry Psychiatry Cataplexy -> modafinil stimulant3792 Psychiatry Psychiatry TELL ME MORE ABOUt thAT.4815 Psychiatry Psychiatry Chelsea has ocpd. Personality disorder. Ego-syntonic.2340 Surgery Surgery RBC scan less invasive than angiography. if colonoscopy neg for LGIB-> do RBC scan next.2476 Surgery GIT hernia-covered with skin vs. omphalocele- covered with peritoneum vs. gastroschisis-butt naked
3182 Surgery Surgery acute diverticulitis ->First ask, complicated vs. uncomplicated?? If complicated (abscess/perf/obstruction/fistula) -> then ask, <3cm (IV antibx) or >3cm (CT drain it)
3221 Surgery Surgery Blunt vs. penetrating trauma. If penetrating -> almost always exploratory lap
3223 Surgery Surgery CO. Colorless. Odorless. Cherry O lips. elevated carboxyhemoglobin level. pulse ox lies. give 100% O2.
3325 Surgery Surgery clean wound but uncertain vaccine status-> just give vaccine. dirty/severe wound -> give vaccine unless recent booster (5 years)
3435 Surgery Surgery crohn's disease: lose calcium bound to fat and can't absorb bile salts -> increased oxalate levels -> stones!
3572 Surgery Surgerylateral injury ("abduction injury")-> tear MCL -> dx valgus stress test vs. LCL doesn't really happen (medial force to knee??) vs. hyperextension/torsional injury-> ACL vs. dashboard injury-> PCL. *popping doesn't tell you anything. everything pops.
4293 Surgery Surgery femoral nerve4364 Surgery GIT SBO- usually caused ADHESIONS (congenital vs. iatrogenic vs. inflammation)
4501 Surgery Surgery back/flank pain after cardiac cath -> retroperitoneal hematoma!! -> dx non-con abd CT; trx supportive, prx don't lift heavy things after cath, and radial arter approach better
4527 Surgery Cardiology large left sided hemothorax after blunt trauma -> AORTIC INJURY (contained or else you'd be dead already)
4527 Surgery Cardiology left-sided hemothorax -> AORTIC INJURY. vs. pneumothorax that does not resolve with chest tube placement -> BRONCHIAL RUPTURE. vs. esophageal rupture-> don't really get with trauma.
4538 Surgery RespiratoryTAKE CARE OF PNEUMOTHORAX BEFORE INTUBATION. distended neck vv-> PT or cardiac tamponade. -> needle decompression and then chest tube placement (also treats hemothorax); if still unstable, FAST for pericardial tamponade
4541 Surgery Cardiology Increased pcwp -> Left heart failure
4552 Surgery Neurology Epidural hematoma -> uncal herniation -> ipsilateral oculomotor and contralateral cerebral peduncle
4554 Surgery Surgery Meniscal tears minimal sx: gradual swelling b/c indirecty perfused, Mcmurray's sign (snap with terminal extension) vs. lightning ligamentous tears: rapid swelling from blood in joint
4698 Surgery Neurology syrinomyelia kind of like central cord syndrome (UE motor and sensory deficits)