UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral...
-
Upload
duongkhuong -
Category
Documents
-
view
212 -
download
0
Transcript of UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral...
![Page 1: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/1.jpg)
UTU Research Faculty of Medicine
![Page 2: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/2.jpg)
Zhi Jane Chen
Lymphocytes and Inflammation
• Th17 and iTreg in inflammatory/autoimmune axis
• Th17 and iTreg differentiation
• Immune and hormonal responses
• Pathogenesis of immune-mediated diseases
BioCity Turku Centre for Lifespan Research
![Page 3: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/3.jpg)
Juha Grönroos
Minimally invasive surgery/Acute appendicitis
• GI surgery
• Pancreatobiliary diseases
• Colorectal cancer
• Endoscopic and laparoscopic biliary and pancreatic
surgery
• Treatment of acute appendicitis
![Page 4: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/4.jpg)
Ulvi Gursoy
Bacterial Signaling Molecules in
Immune Response Regulation and
Biofilm Eradication; Exploring the Role
of Nrf2/ARE Pathway in Periodontitis
• Bacterial messenger molecule analogs
• Biofilms and Biomarkers
• Molecular mechanisms of the Nrf2/ARE
pathway
![Page 5: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/5.jpg)
Merja Haaparanta-Solin
PET imaging of neuropathological changes
in animal models of Alzheimer's disease
• Alzheimer's disease
• endocannabinoid modulation
• brain energy metabolism
• neuroinflammation
• norepinephrine function
• beta-amyloid plaque and tau formation
BioCity Turku Translational Infectious Disease and Immunity Research Programme,
and Turku Brain and Mind Center
![Page 6: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/6.jpg)
Terho Heikkinen
Respiratory tract infections in children:
epidemiology, management, prevention,
and total impact on the society
• Pediatrics
• Respiratory infections
• Vaccinations
• Health economics
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 7: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/7.jpg)
Terhi Heino
The role of mesenchymal stem cells
in fracture healing
• Mesenchymal stem cells
• Bone formation and regeneration
• Signaling mechanisms in fracture healing
• Molecular and cellular interactions
BioCity Turku Centre for Lifespan Research
![Page 8: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/8.jpg)
Veijo Hukkanen
Herpesviruses as friends and enemies
• latency of HSV and its prevention
• delivery and targeting methods for HSV gene
therapy
• HSV diversity
• HSV diagnostics
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 9: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/9.jpg)
Risto Huupponen
Pharmacoepidemiology of statins and
oral anticoagulants
• the association of adherence to statins on
therapeutic outcomes and on the cost-
effectiveness of statin treatment
• drug interactions with warfarin at the
population level
![Page 10: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/10.jpg)
Jukka Hytönen
Lyme borreliosis: a comprehensive approach
• Prevalence of ticks and epidemiology of
borrelioses
• Susceptibility of humans to disseminated LB
• Pathogenesis of LB: adhesins, tissue tropism
• Molecular and cellular events in neuroborreliosis
• Diagnostics for borrelioses, biomarkers
• Development of PET/CT imaging of LB
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 11: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/11.jpg)
Pekka Hänninen
Laboratory of Biophysics
• instrumentation and methods for light microscopy,
correlative multimodal microscopy and bio-analysis
• New super-resolution techniques: 3D super
resolved tomography, nano-probes, in-vitro models
and photoacoustic microscopy methods (PAM)
• Chemical fingerprinting technique
BioCity Turku Diagnostic Technologies and Applications
![Page 12: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/12.jpg)
Erika Isolauri
Neonatal exposures, Adverse outcomes, Mucosal
immunology and Intestinal microbiota (NAMI)
• The impact of early microbial colonization patterns on
the growth of children/obesity risk - long-term follow-up.
• Characterizing foeto-maternal microbe contact.
• Defining a microbial marker as an indicator of the risk of
complicated pregnancy impacting on dysbiosis and
abnormal growth in the child.
BioCity Turku Centre for Lifespan Research
![Page 13: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/13.jpg)
Kaisa Ivaska
Bone and energy metabolism
• Diabetic bone disease
• Effects of energy metabolism on bone
cells and bone microenvironment
• Osteoblasts
• Osteocalcin
BioCity Turku Centre for Lifespan Research
![Page 14: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/14.jpg)
Panu Jaakkola
Oxygen sensing molecules in kidney cancer
• Renal clear cell carcinoma (ccRCC)
• hypoxia-inducible factor (HIF)
• prolyl hydroxylase enzymes (PHD) 1-3
• Hippel-Lindau tumor suppressor protein (pVHL)
BioCity Turku Receptor Programme
![Page 15: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/15.jpg)
Ilkka Julkunen
Mechanisms of activation of innate immunity in
viral infections
• viral infections, viral proteins (vaccines) and viral
genetic material in the activation of host immune
responses (DCs, macrophages)
• novel mechanisms to prevent the replication of viruses
and excessive inflammatory responses
• Seroepidemiological studies: Influenza and RSV
• Disease mechanisms in pandemic influenza vaccine
induced narcolepsy
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 16: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/16.jpg)
Hannu Järveläinen
Extracellular matrix macromolecules in health
and disease – with special reference to
cardiovascular diseases and cancer
• Extracellular matrix macromolecules - proteoglycans
and hyaluronan - in atherogenesis, excess
angiogenesis and tumorigenesis.
• Decorin and decorin-based gene therapy
• Angiogenesis
Associated to BioCity Turku Computational and Molecular Methodologies for Life Sciences
![Page 17: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/17.jpg)
Tuomas Kiviniemi
CAREFIB Consortium
• atrial fibrillation
• a retrospective epidemiological CAREAVR study
• a prospective CAREBANK biobank
• a prospective CARECLOSURE trial.
BioCity Turku Diagnostic technologies and applications
![Page 18: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/18.jpg)
Markku Koulu
Prenatal programming of energy
balance and metabolism
• Metformin-induced metabolic programming
and changes in gene expression
• Metabolic effects of prenatal metformin
exposure in different pre- and postnatal
conditions
![Page 19: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/19.jpg)
Veli-Matti Kähäri
Skin cancer and proteinase research group
• Molecular mechanisms in progression, invasion
and metastasis of cutaneous squamous cell
carcinoma (cSCC)
• new biomarkers for evaluating the risk of
progression and metastasis of cSCC and identify
novel therapeutic targets
• the role and regulation of proteinases MMPs in
tissue repair and fibrosis
BioCity Turku Receptor Programme
![Page 20: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/20.jpg)
Eija Könönen
Periodontal inflammation and infection-
induced inflammation
• periodontal infection and infection-induced
inflammation
• oral biofilm-host interaction
• impact of periodontal disease on systemic conditions
• salivary diagnostics in periodontology
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 21: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/21.jpg)
Riitta Lahesmaa
Molecular Systems Immunology
• Molecular markers in type 1 diabetes (T1D) –
integration of omics, autoantibody, genetics and
demographic data
• Holistic approach in characterization of the novel
genes and pathways in with primary human
CD4+ T helper (Th) cell differentiation
BioCity Turku Centre for Lifespan Research
![Page 22: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/22.jpg)
Tiina Laitala-Leinonen
RNA- or trauma -mediated gene regulation
• Short regulatory RNA physiology: siRNAs, shRNAs,
microRNAs
• Short regulatory RNA involvement in tissue healing
after trauma
• (BAAC) Biological Assessment of Acute Concussions
in athletes
• Entesophyte project: calcific spur formation at the
Achilles tendon
• EUROCLAST: extensive vesicular trafficking in bone-
resorbing osteoclasts
BioCity Turku Centre for Lifespan Research
![Page 23: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/23.jpg)
Liisa Lehtonen
Neonatal Research
• The PIPARI Study
• Close Collaboration with Parents - Evaluation of the
Intervention
• International Closeness Survey in the SCENE Group
• International Network for Evaluating Outcomes
(iNeo) of Neonates
BioCity Turku Centre for Lifespan Research
![Page 24: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/24.jpg)
Lund Riikka
Biomedical Epigenomics
• Regulation of stem cell state and transformation
• Epigenetic mechanisms of childhood leukemia
Epigenomics of childhood rhinovirus-induced
wheezing and asthma
• Epigenomic alterations in aging and Alzheimer’s
disease
BioCity Turku Computational and Molecular Methodologies for Life Sciences
![Page 25: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/25.jpg)
Pieta Mattila
Lymphocyte Cytoskeleton Group
• B cell activation
• Actin cytoskeleton
• Antigen receptor signaling and
remodeling of the cytoskeleton
• Advanced microscopic methods
BioCity Turku Receptor Programme
![Page 26: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/26.jpg)
Sari Mäkelä
Diet and cancer
• Dietary factors in hormone-dependent cancers (breast
and prostate cancer)
• Altered sex steroid action and obesity-related metabolic
dysregulation
• Plant-derived polyphenols (e.g. lignans, stilbenoids,
flavonoids)
• Preclinical in vivo models
BioCity Turku Center for Lifespan Research
![Page 27: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/27.jpg)
Jorma Määttä
Myeloid cells in regulation of chronic
inflammation, autoimmunity and tumor
microenvironment
• Myeloid cells in immune response
• Tumor associated macrophages and tumor
microenvironment
• Exosomal miRNA communication
• Treatments based on bisphosphonate metabolites
BioCity Turku Centre for Lifespan Research
![Page 28: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/28.jpg)
Matej Orešič
Systems Medicine
• Metabolomics
• Integrative bioinformatics
• Personalized medicine
• MZmine open source project = software for
metabolomics data processing
BioCity Turku Centre for Lifespan Research
![Page 29: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/29.jpg)
Ville Peltola
Detecting viral infections and targeting
antibiotic use in children with MxA protein
and other biomarkers
• Viral and bacterial respiratory tract infections in
children
• Detecting viral infections and targeting antibiotic
use in children with MxA protein and other
biomarkers
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 30: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/30.jpg)
Juha Peltonen
Cancer syndrome / Rasopathy NF1:
pathoetiology and epidemiology
• Neurofibromatosis (NF1)
• NF1 mutation
• Hyperactivation of Ras pathway
• Altered drug metabolism
BioCity Turku Centre for Lifespan Research
![Page 31: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/31.jpg)
Sirkku Peltonen
Neurofibromatosis and Cell-cell Interaction Group
• Epidermal tight junctions in skin diseases
• Cell-cell interactions of and gene expression of Schwann
cells
• Gene expression profiling of cultured keratinocytes
• Basic science aspects, translational studies and clinical
research of neurofibromatosis 1.
BioCity Turku Centre for Lifespan Research
![Page 32: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/32.jpg)
Matti Poutanen
Mechanisms of Steroid Hormone Action
• Intracrinology
• The role of HSD17B enzymes in regulating the amount
and type of ligand for nuclear receptor action
• The role of local sex steroid synthesis in the
etiopathogenesis of breast and prostate cancer
• The role of intra tissue sex steroid synthesis and steroid
hormone action in endometrium and the role of the
enzymes in etiopathogenesis of endometriosis
BioCity Centre for Lifespan Research
![Page 33: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/33.jpg)
Arto Pulliainen
Cellular microbiology – how bacteria
manipulate host cell signaling
• Bacterial pathogenesis and new human
bacterial pathogens
• Identification and function of bacterial
toxins/effector proteins
• Development of new antimicrobials
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 34: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/34.jpg)
Pia Rantakari
Endothelium and embryonic leukocyte
migration
• Leukocyte migration during fetal ontogeny
• Embryonic origin of cells in adults
• Tissue development and adult pathophysiology
![Page 35: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/35.jpg)
Jaana Rautava
Oral mucosal diseases and oral cancer
• Human papillomavirus (HPV) infection in the
mouth and the interaction between HPV and
bacterial microbiome
• Potentially malignant lesions/conditions of oral
mucosa
• Crohn’s disease and oral diseases
• Medication related osteonecrosis of the jaws
![Page 36: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/36.jpg)
Päivi Rautava
• The Finnish Family Competence Study 1985-
• Reproductive and Sexual Life Span of Women 2010-
• The Development of Maternity and Child Health Care
Services 2010-
• The development of health care service structure by
using the information resources of the electronic
patient records and other registries 2011-
BioCity Turku Centre for Lifespan Research
![Page 37: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/37.jpg)
Samuli Rautava
Early microbial contact and child health
• Modulating early microbial contact infants at risk of
aberrant compositional development of gut
microbiota
• Early antibiotic exposure, gut microbiota and risk of
disease
• Gut microbiota and preterm birth - from prediction to
prevention
BioCity Turku Centre for Lifespan Research
![Page 38: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/38.jpg)
Teijo Saari
Precision Medicine in Anesthesiology:
Individualization of Pain Therapy and Perioperative
Care with Pharmacometric and Omics Studies
• Pharmacokinetics and –dynamics (PK-PD)
• PK-PD models for drugs
• Pharmacometric model development
• Individualized therapy
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 39: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/39.jpg)
Sanna Salanterä
Digital Nursing Turku
• Knowledge-Based Management in the Acute Care Setting
and Perioperative Nursing
• IoT for Basic Nursing Care
• Basic Nursing Care (The Step)
• Tailored Information for Patient’s and Professionals (Tailor)
• Research Group on Health Games (TEPE)
![Page 40: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/40.jpg)
Paulina Salminen
Acute appendicitis and bariatric surgery studies
• Clinical surgical studies and translational research
• Pathophysiological mechanisms of surgically treated
diseases
• Bariatric surgery and obesity
• Acute appendicitis
• Gut microbiota
• Inflammatory biomarkers
![Page 41: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/41.jpg)
Eriika Savontaus
Neuroendocrine mechanisms in pathogenesis
and therapeutics of cardiometabolic diseases
• Neuropeptides NPY and POMC (melanocortins)
• Obesity, body weight and composition
• Tissue-specific mechanisms of NPY and
melanocortin action
• Drug development for metabolic and cardiovascular
diseases
BioCity Turku Centre for Lifespan Research
![Page 42: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/42.jpg)
Harry Scheinin
Anesthesia Mechanisms
• Exploration of neural correlates of human
consciousness.
• New tools for distinguishing consciousness,
connectedness and responsiveness.
• Development of EEG-based methods to
measure consciousness and the depth of
general anesthesia.
Turku Brain and Mind Center
![Page 43: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/43.jpg)
Johanna Schleutker
Genetic predisposition to cancer
• Prostate and breast cancer genetics
• Identification of predisposing genes
• Diagnosis and treatment
• Prognostic biomarkers
BioCity Turku Receptor Programme
![Page 44: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/44.jpg)
Sari Stenholm
Life-long determinants of healthy aging
• Healthy aging at work and at retirement -
Finnish Retirement and Aging Study (FIREA)
• Integrated Datasets across Europe for Ageing
Research (IDEAR) network
• Psychosocial work environment and healthy
ageing
![Page 45: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/45.jpg)
Riitta Suhonen
Older Individuals' Health, Nursing and
Services
• Health, health determinants and promotion of health
• Complex service systems
• Nursing care
![Page 46: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/46.jpg)
Petri Susi
Molecular determinants of picornaviral
disease
• Diagnostics: development of detection assays
• Viral tropism in model systems
• Virus evolution: natural sequence variation and
its consequences in infectivity
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 47: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/47.jpg)
Pekka Taimen
Nuclear Lamins and Human Disease
• Nuclear lamina proteins
• Laminopathies
• Cancer progression
• Lamin mutations
https://fi.linkedin.com/in/pekka-taimen-52636366
![Page 48: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/48.jpg)
Olli Tenovuo
Traumatic brain injury research group
• Mechanisms of TBI
• Individual diagnostics of TBI
• Detection and characterization of injury
types and mechanisms
Turku Brain and Mind Center
![Page 49: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/49.jpg)
Mika Teräs
Medical physics research
• Instrumentation in nuclear medicine
imaging
• Dual gating in cardiac PET
• Perfusion in cardiac imaging
• Optimization in radiation dosimetry
![Page 50: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/50.jpg)
Arzu Tezvergil-Mutluay
Adhesive Dentistry Research Group
• Tooth-restorative materials
• Tissue engineering
• Nanoscale biomimetic materials and
biomimetic remineralization
• Metalloproteinase regulation
BioCity Turku Biomaterial and Medical Device Research Programme
![Page 51: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/51.jpg)
Jorma Toppari
Developmental determinants of
reproductive health and type 1 diabetes
• Reproductive health
• Reproductive hormones
• Environment and endocrine disruptors
• Cohort studies
BioCity Turku Centre for Lifespan Research
![Page 52: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/52.jpg)
Johanna Tuomela
Innate immunity receptor (TLR9) in cancer
• Breast and prostate cancer
• Toll-like receptor-9 (TLR9)
• Molecular pathways in cancer cells
• Biomarkers and drug targets
BioCity Turku Centre for Lifespan Research
![Page 53: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/53.jpg)
Waris, Matti
Host response and molecular variation in
respiratory and enteric virus infections
• Respiratory and enteric viruses
• Molecular diagnostics tools: microarray
techniques with phosphor reporters
• treatment and prevention of respiratory virus
infections.
• Associated projects:• Innate immunity in rhinovirus infections
• Application of MxA assay in clinical diagnotics
• Epidemiology of respiratory virus infections
• AIRBORNE: Assessing hospital-aquired infection risks
to healthcare workers from patients infected with
aerosol-transmitted pathogens
BioCity Turku Translational Infectious Disease and Immunity Research Programme
![Page 54: UTU Research Faculty of Medicine · 2018-06-05 · Pharmacoepidemiology of statins and oral anticoagulants • the association of adherence to statins on therapeutic outcomes and](https://reader036.fdocuments.in/reader036/viewer/2022070612/5b890e5e7f8b9abe1e8cb6f4/html5/thumbnails/54.jpg)
Jukka Westermarck
Cancer Cell Signaling
• Human cancers
• Phosphorylation
• Protein phosphatase 2A (PP2A)
• CIP2A (PP2A inhibitor protein)
BioCity Turku Receptor Programme