Urinary and Lymphatic Systems. Functions of Lymphatic System Filters lymph fluid Returns leaked...

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Urinary and Lymphatic Systems

Transcript of Urinary and Lymphatic Systems. Functions of Lymphatic System Filters lymph fluid Returns leaked...

Urinary and Lymphatic Systems

Functions of Lymphatic System

Filters lymph fluid

Returns leaked fluid to circulatory system

Produces and modifies cells of immune system to fight infection

Major Organs of the Lymphatic System

Lymph Fluid

Lymph Capillaries

Lymph Vessels

Lymph Nodes (nonsecreting "glands“)

Thymus

Spleen

Tonsils

Major Organs of the Lymphatic System

Lymph Fluid: The clear fluid found outside the cells which bathes the tissues. It is collected, filtered, and transported by the lymphatic system from around the tissues to the blood of the circulatory system.

Major Organs of the Lymphatic System

Lymph Capillaries – collect lymph fluid from the tissues of the body

Lymph Capillary Animation: http://www.lymphnotes.com/article.php/id/151/

Lymph Capillaries

Thin walled - pick up and recycle extra tissue fluid

During inflammation, lymph capillaries can absorb:– Cell debris– Pathogens– Cancer cells

Lymph circulation due to ?

Major Organs of the Lymphatic System

Lymph Vessels transport lymph fluid to the circulatory system.

Damaged valves or blockedlymph vessels ???

Lymphatic vessels

comparable in structure to veins

Lymph Transport

• The lymphatic system lacks a pumping organ

• To propel lymph, vessels rely on: – Pulsations of nearby

arteries– Movement of muscles

throughout the body– Contractions of smooth

muscle in the walls of the lymphatic vessels

Lymphoid Organs – aid in the production of lymphocytes (WBC)

• Lymph Nodes

• Spleen

• Thymus

• Tonsils

Lymphocytes • Lymphocytes are the

main cells involved in the immune response

• Two main varieties:– T cells– B cells

Lymphocytes

T cells and B cells protect the body against antigens

1. Antigen – anything the body perceives as foreign– Bacteria and their

toxins; viruses– Mismatched RBCs

or cancer cells

Lymphocytes

2. T cells – Manage the immune

response– Attack and destroy

foreign cells

3. B cells – Produce plasma

cells, which secrete antibodies

– Antibodies immobilize antigens

Bone Marrow: Lymphopoiesis

Lymphocytes are later also produced in thymus, spleen and tonsils

Fig 23.7

Lymph Nodes - • Primary lymphatic organs

of the body• Found within connective

tissue and along lymphatic vessels

• 2 basic functions:– Filtration –remove

microorganisms, dead cells, and debris

– Immune system activation – monitor and attack antigens

Spleen

• Largest lymphatic organ

• Functions:– Site of lymphocyte

production – Immune surveillance

and response– Cleanses the blood by

removing dead red blood cells

ThymusOnly lymphoid organ that does NOT

fight antigens, it functions as “T-cell academy” – modifies T-cells

Tonsils & Adenoids

• Simplest lymphatic organs

• Trap bacteria and other antigens which work their way into the follicles where they are destroyed

Disorders of the Lymphatic System

• Edema Accumulation of lymph fluid caused by blockages in the lymphatic vessels

Disorders of the Lymphatic System

• Severe combined immunodeficiency (SCID) syndrome – genetic disorder in which a person is born missing T cells (white blood cells that identify and attack perceived “invaders”) and affect the function of the B cells (white blood cells that produce antibodies against infection)

Disorders of the Lymphatic System

– An autoimmune disorder is a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue. There are more than 80 different types of autoimmune disorders.

• Rhuematoid Arthritis• Type I Diabetes• Psoriasis • Vitiligo

The Urinary System

Functions of Urinary System

● Regulate fluid balance (fluid volume) of the body

● Excrete waste products from the blood

Stabilize blood pH

Regulate ion concentrations in the blood

Kidney LocationKidney Location

Major Organs of the Urinary System

– Kidneys– main organs of the urinary system; have specialized cells called Nephrons that filter harmful poisons like urea from the blood

Major Organs of the Urinary System

– Kidneys– main organs of the urinary system; have specialized cells called Nephrons that filter harmful poisons like urea from the blood

Major Organs of the Urinary System

– Bladder –stores urine

Major Organs of the Urinary System

– Bladder –stores urine

Major Organs of the Urinary System

– Ureters– tubes that connect kidneys to bladder

Major Organs of the Urinary System

– Ureters– tubes that connect kidneys to bladder

Major Organs of the Urinary System

– Urethra– tube thru which urine exits the body

Major Organs of the Urinary System

– Urethra– tube thru which urine exits the body

Major Organs of the Urinary System

– Kidneys– main organs of the urinary system; have specialized cells called Nephrons that filter harmful poisons like urea from the blood

– Bladder –stores urine – Ureters– tubes that

connect kidneys to bladder

– Urethra– tube thru which urine exits the body

2 Categories of Waste Removed By the Kidneys

(produced by cellular respiration)

Excretion and other body systems

Cross section

Kidney Stones

Renal failure

• Acute (sudden) kidney failure is the sudden loss of the ability of the kidneys to remove waste and concentrate urine.– Can be caused by: Dehydration, Hemorrhage,

Injury, Septic shock, Serious illness, Surgery