Funded by an NSF Science and Technology Center grant (CMMI):15-48571

Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA

Day 1 : SEPTEMBER 13 8:00 – 8:30 AM

Registration and Coffee/Continental Breakfast 3rd Floor, Singh Center

8:30 – 8:45 Welcome - Vijay Kumar, Dean, Penn Engineering - Vivek Shenoy, Director, CEMB

Moderator: Paul Janmey, University of Pennsylvania

8:45-9:15 AM Yu-li Wang, Carnegie Mellon University Contact Inhibition and Contact Following as Complementary Cell-Cell Interactions to Coordinate Collective Behavior and Promote Collective Migration

9:15-9:45 Ovijit Chaudhuri, Stanford University

Mechanical Regulation of Tumor Growth and Basement Membrane Invasion

9:45-10:00 Alexander Bennett, University of Pennsylvania Manipulating Magnetorheological Elastomers to Modify Cell Morphology

10:00-10:15 Emile Kraus, University of Pennsylvania

Rheology and Mechanobiology of Two Early Animals

10:15-10:45 AM Coffee Break 3rd Floor, Singh Center

Moderator: Elizabeth Haswell, Washington University in St. Louis

10:45-11:00 AM Richard Vincent, Jr, New Jersey Institute of Technology Fabrication of Natural and Synthetic Fibrous Matrices for Plant Cell Growth

11:00-11:30 Iris Meier, The Ohio State University

A Role for Plant LINC Complexes in Pollen Tubes, Guard Cells, and Nodulation

11:30-12:00 PM Gabriele Monshausen, Pennsylvania State University Cell Wall Integrity Sensing in Plants – A Role for the Receptor-Like Kinase FERONIA?

12:00-1:00 PM LUNCH and Poster set-up Galleria, 1st Floor, Singh Center

Funded by an NSF Science and Technology Center grant (CMMI):15-48571

Day 1: September 13, continued

Moderator: E. Michael Ostap, University of Pennsylvania

1:00-1:30 PM Margaret Gardel, University of Chicago Controlling Epithelial Cell Shape

1:30-2:00 Pakorn Tony Kanchanawong, National University of Singapore, Mechanobiology Institute

Probing the Actin Cortex in Embryonic Stem Cells by Super-resolution Microscopy

2:00-2:15 Farid Alisafaei, University of Pennsylvania A Chemo-Mechanical Model for Cytoskeletal Control of Nuclear Morphology

2:15-2:30 Delaram Shakiba, Washington University in St. Louis

Remodeling of Collagen by Fibroblasts in Three-Dimensional Culture

2:30-2:45 Devon Mason, University of Pennsylvania Persistent Motility Requires Transcriptional Feedback Control of Actomyosin Equilibrium by YAP/TAZ

2:45-3:15 PM Coffee Break

3rd Floor, Singh Center

Moderator: Richard Assoian, University of Pennsylvania

3:15-3:30 PM Erin Masucci, University of Pennsylvania Engineering Biomimetic Models to Investigate Organelle Transport Through Complex 3-Dimensional Cytoskeletal Geometries in Neuronal Dendrites

3:30-4:00 Roger Kamm, Massachusetts Institute of Technology

In Vitro Model of a Human Neuromuscular Junction

4:00-4:30 Valerie Weaver, University of California, San Francisco Forcing Tumor Risk and Progression

4:30- 4:45 Abigail Loneker, University of Pennsylvania Lipid Loading of Hepatocytes Leads to Nuclear Compression and Deformation

4:45-5:00 Matthew Davidson, University of Pennsylvania

Electrospun Fibrillar Biomaterial Platforms with Tunable Mechanics as Fibrosis Disease Models

5:00 – 7:00 PM Reception and Poster Session

Galleria, 1st Floor, Singh Center

Funded by an NSF Science and Technology Center grant (CMMI):15-48571

Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA

Day 2 : SEPTEMBER 14 8:30 – 9:00 AM

Registration and Coffee/Continental Breakfast 3rd Floor, Singh Center

Moderator: Guy Genin, Washington University in St. Louis

9:00-9:30 AM Alex Mogilner, New York University Force Transduction in Interconnected Contractile Networks

9:30-10:00 John Lowengrub, University of California at Irvine Mechanical Feedback and Stress Relaxation in Solid Tumors

10:00-10:15 Julie Heffler, University of Pennsylvania A Balance of Cytoskeletal Forces Maintains Nuclear Architecture in the Cardiomyocyte

10:15-10:45 AM Coffee Break

3rd Floor, Singh Center

Moderator: Robert Mauck, University of Pennsylvania

10:45-11:00 AM Yuntao Xia, University of Pennsylvania Nuclear Rupture at Sites of High Curvature Compromises Retention of DNA Repair Factors

11:00 – 11:15 Su Chin Heo, University of Pennsylvania

Nuclear Softening Expedites Interstitial Cell Migration in Fibrous Dense Connective Tissues

11:15-11:45 GV Shivashankar, National University of Singapore, Mechanobiology Institute Nuclear Reprogramming: A Leap Forward Through Mechanobiology

11:45-12:15 PM Doris Wagner, University of Pennsylvania

How to Make A Flower – Epigenetic, Transcriptional and Mechanical Inputs

12:15 – 12:30 PM

Closing Comments, Vivek Shenoy 3rd Floor, Singh Center

12:30 PM LUNCH Galleria, 1st Floor, Singh Center