Unit 1: DNA and the Genome Key area 7: Evolution.

Unit 1: DNA and the Genome

Key area 7: Evolution

CFE Higher BiologyDNA and

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Evolution

Watch the stated clearly “Evolution” clip (9 min).

Evolution is the gradual change in the characteristics of a population of organisms over successive generations as a result of variation in the population’s genomes.


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Inheritance

Genetic material can be inherited by:1. Vertical transfer2. Horizontal transfer


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1. Vertical transfer of genetic material

Genes (sequences of protein coding DNA) are transferred from parents down to their offspring.

This can happen by:(a)Sexual reproduction(b)Asexual reproduction


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(a) Sexual reproductionThis involves two

parents who differ from one another genetically.

Offspring inherit different combinations of genes from each parent.

Brown wavy hair

Blue eyes

Dimples

Straight red hair

Brown eyes

No dimples


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(b) Asexual reproductionIs reproduction

from a single parent.

Produces offspring who are genetically identical to the parent.


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2. Horizontal transfer of genetic material (prokaryotes)

In prokaryotes (who reproduce using asexual reproduction) – genetic material can be transferred from one cell to another through horizontal gene transfer.


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Horizontal gene transfer can occur in three ways:

(a)Transformation – when cells are destroyed bits of their DNA float around and can be picked up by new cells.


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(b) Transduction – occasionally when viruses replicate some host DNA is packaged up with the virus. This then enters new cells with the virus.


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(c) Conjugation – A temporary connection called a conjugation tube forms between touching cells. Plasmid DNA is then copied from one cell to another.


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Rapid evolutionary changeIn early evolution of prokaryotes there was

a lot of horizontal gene transfer (HGT) because obtaining a gene from a neighbour is much faster than waiting for one to evolve.

This allowed rapid evolution of prokaryotes.However this is a risky strategy as there are

no guarantees the transferred genetic material will give an advantage.


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Spread of antibiotic resistance

A significant amount of HGT still occurs in modern day prokaryotes.

Resistance to antibiotics has occurred through the transfer of plasmids carrying antibiotic resistance genes from bacteria to bacteria.


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Horizontal transfer of genetic material (eukaryotes)

Although less common, horizontal gene transfer can occur in eukaryotes:

(a)From prokaryotesAgrobacterium tumefaciens, is a

bacterium, which infects plant cells with a plasmid that integrates into the genome of the plant.


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(b) From virusesSome viruses can integrate their DNA

into the host’s genome. Where they remain dormant (as a provirus) until they reproduce and destroy the cells.

e.g. Herpes virus HIV


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Selection and evolution

Use the information on the worksheet to produce a timeline for the evolution from the universal common ancestor to the last ice age.


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Natural selection

In 1858 Charles Darwin and Alfred Wallace presented a theory suggesting that the main driving force for evolutionary change is natural selection.


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Watch the Natural Selection video clip (10 min)


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Organisms produce more offspring than the environment can support

All members of a species show variation from each other

A struggle for existence occurs and many offspring die before they can reproduce

Only those who are better adapted to the environment (the fittest) will survive and bred and

pass those adaptations on to their offspring.

This process is repeated generation after generation causing gradual change in the characteristics of a

species.


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Natural selection is a non-random process that results in the increase in frequency among a population of individuals of those genetic sequences that confer an advantage on members of the population and aid their survival.


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Sexual selection

Sexual selection is a “special case” of natural selection – where selection is driven by the organism’s ability to get a mate.

Sexual selection is the process of selection for traits that increase reproductive success.


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It operates by the following mechanisms:1. Male to male competitionMales compete aggressively to defend

territories and get access to females.Larger, stronger males or males with better

“weapons” win mating rights and pass those alleles on.


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Watch the following clip about sexual selection


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2. Female choiceFemales select males which they consider

high quality depending on the traits they display.


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Selection of quantitative traits

Continuous variables, such as height, mass, skin colour, hair colour etc. are controlled by many genes and are described as being due to polygenic inheritance.


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When you graph data for continuous variable in a large population you should get a “bell shaped curve” or normal distribution.

Increasing value of inherited characteristic e.g. height (m)

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(a) Stabilising selection

Increasing value of inherited characteristic

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Selection pressure goes against extreme variants and favours the intermediate versions of a trait. Leads to a reduction in genetic diversity.

e.g. Human birth mass remains with in range of 3-4 kg. Babies with lower mass more susceptible to disease, higher mass have difficulties during birth.


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(b) Directional selection


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Common during period of environmental change. Selection favours a version which was initially less common causing a progressive shift in the mean value.

e.g. European black bears increased in mass during each ice age – as larger bodies lose relatively less heat than smaller ones.


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New Mean


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(c) Disruptive selection


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Selection pressure selects extreme versions of a trait at the expense of the intermediate versions. Can result in the population being split into two distinct groups. This is the driving force behind sympatric speciation (see later in topic).


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Genetic drift

The total of all the different genes in a population is called the gene pool.

If a species is under no selective pressure, frequencies of individual alleles will stay the same from generation to generation.


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Genetic drift is the random increase or decrease in frequency of genetic sequences.

This occurs due to:(a)Sampling error(b) Neutral mutations(c) Founder effects


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(a) Sampling error

In a small population, not all alleles are passed onto the next generation and some may be ‘lost’.


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(b) Neutral mutations

These change the nucleotide sequence of a gene, but do not change the amino acids coded for. They are not subject to natural selection, but are affected by genetic drift.


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(c) Founder effects

If a population becomes isolated and is not large enough to contain the entire gene pool, gene frequencies will be different in that population.

An example of the founder effect can be seen in the different blood group allele frequencies in different human populations.


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People % population with blood group

A B AB O

Chinese 31 28 7 34

Sioux native

americans

7 2 0 91

North America first populated by a small unrepresentative group of Asian people who migrated across the land bridge, now the Bering strait, and became separated.


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Speciation

Is the formation of a new biological species. It is brought about by evolutionary change.

There are two types of speciation:(1)Allopatric speciation(2)Sympatric speciation


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(1) Allopatric speciation

This occurs when gene flow between two (or more) populations is prevented by a geographical barrier.

e.g. rivers, mountain ranges, desert, sea


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In summary…

Large interbreeding population


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Isolation of populations

Population A Population B


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Large mutant

Small mutant

Separate populations mutate randomly –new variation


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Natural selection favours mutants

e.g. Large mutant may favour dry conditions

e.g. Small mutant may favour wet conditions


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Species A Species B

Over a long period of time natural selection increases frequency of new alleles


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Speciation has occurred. Species A and B cannot interbreed even if barrier is removed


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(2) Sympatric speciation

Two (or more) populations live in close proximity in the same environment but still become genetically isolated.

This happens due to a behavioural or ecological barrier or by the occurrence of polyploidy (in plants only).


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In summaryLarge interbreeding population sharing the same ecological niche.

(e.g. Fruit flies living on hawthorn bushes)


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Alternative ecological niche appears.

(e.g. new species of apple tree introduced by humans)

Some members of the population start to exploit the new niche


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The two populations now exploit different resources (e.g. food source) and no longer interbreed.

Behaviour has become an isolating barrier.


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Mutants better adapted to exploit the new resources appear and successfully breed.

(e.g. better camouflaged on apples)


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Natural selection favours the new mutants and eventually over a period of time two genetically distinct species are formed which can no longer interbreed.


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Hybrid zones

An environment may contain several sub-populations of a species which cannot all interbreed.

AB C

D

Hybrid zones


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Each sub-population can breed with its neighbour but may not be able to breed with more distant members of the species.

Hybrid zones exist where interbreeding is possible and as a result genes are able to flow between the sub-populations.

AB C

D

Hybrid zones


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If populations B or C become extinct, gene flow is disrupted and populations A and D cannot breed together and therefore become two separate species .

A B C D

Hybrid zones

A C D

Hybrid zones

Unit 1: DNA and the Genome

Key area 8: Genomic sequencing

DNA sequencing, phylogenetics, comparisons of sequences, personal genomic

sequencing


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Unit 1: DNA and the Genome Key area 7: Evolution.

Documents

Transcript of Unit 1: DNA and the Genome Key area 7: Evolution.