Unilife Corp ($UNIS) - Innovative Drug Delivery Device Solutions

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Innovative Drug Delivery Device Solutions Ramin Mojdeh, Ph.D. Executive Vice President and Chief Operating Officer UBS Specialty Pharma Conference May 2011

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Ramin Mojdeh, Ph.D. Executive Vice President and Chief Operating Officer UBS Specialty Pharma Conference May 2011

Transcript of Unilife Corp ($UNIS) - Innovative Drug Delivery Device Solutions

Page 1: Unilife Corp ($UNIS) - Innovative Drug Delivery Device Solutions

Innovative Drug

Delivery Device

Solutions

Ramin Mojdeh, Ph.D.

Executive Vice President and

Chief Operating Officer

UBS Specialty Pharma Conference

May 2011

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Cautionary Note Regarding Forward-Looking Statements

This presentation contains forward looking statements under the safe harbor provisions of the US securities laws. These forward-looking statements are based on management’s beliefs and assumptions and on information currently available to our management. Our management believes that these forward-looking statements are reasonable as and when made. However you should not place undue reliance on any such forward looking statements as these are subject to risks and uncertainties.  Please refer to our press release and our SEC filings for more information regarding the use of forward looking statements.

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Page 3: Unilife Corp ($UNIS) - Innovative Drug Delivery Device Solutions

Emerging global leader in innovative drug delivery device solutions

Enable and enhance delivery of drugs by pharmaceutical customers

Rapidly expanding pipeline being driven by customer needs

Unifill – world’s only prefilled platform with integrated safety

NASDAQ listed (UNIS) with state-of-the-art facility in York, PA

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Introducing Unilife

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$30B Injectable drug delivery device market in 2015, 12.3% CAGR

Large macromolecule composition of pharmaceutical pipeline

Safety legislation and sharps management

Devices drive patient acceptance, preference and adherence

Emerging healthcare needs of aging global population

Rising global healthcare standards creating strong market potential

Improved outcomes and economics with use of unit-dose and ready to administer formats

Trend to patients self-administration of injectable drugs

Patent cliff - 30 biologics with $51B sales expire by 2015

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Attractive Market Trends and Opportunity

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Innovative device solutions for commercial drugs/biosimilars

Integrated proprietary primary drug delivery devices with value-add features

Target and address emerging unmet needs for pipeline drugs

Pharmaceutical collaborations – specialized devices for novel drugs

Target high-end of market for differentiated devices, high margins

Strategic sourcing of components

In-house manufacturing and final assembly

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Strategic Focus

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Technology pipeline developed in partnership with customers

Directly responding to emerging customer needs including: Integrated primary drug delivery devices with value-add features and

customization

Advanced syringe systems with integrated safety and transfer mechanisms

Dry drug reconstitution and delivery technologies

Large-volume viscous drugs delivery technologies

Targeted organ delivery devices

Multi-chamber proprietary primary containers and delivery systems

Reusable and disposable self administration device technologies

Technology portfolio can be leveraged to develop customized device concepts according to specific customer needs

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Customer-Driven Technology Pipeline

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World’s first and only prefilled syringes with integrated safety

Now in production

Controlled retraction into barrel

Needle locked after use for convenient, compact disposal

Unifill – The Leading Edge of Our Portfolio

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Primary drug delivery device with integrated safety

Direct substitute for current prefill and safety prefill syringes

Powerful brand differentiation

Streamlines fill-finish and packaging process

Optimal protection

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Unifill as a Game Changer

+Ancillary safety needle

Standard Prefill

Syringe

Current Safety

Syringe

+Ancillary safety Device

Standard Prefill

Syringe

Current Safety

Syringe

Direct Substitute

Unifill Platform

2.5B Units Annually

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Technology solves a technical challenge most thought impossible

Sanofi invested $40MM for access rights to Unifill

Ready for initial shipment in July – well ahead of original schedule

Current capacity of 60MM units, planned 150MM unit line extension

Success in the Face of a Big Challenge

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Patient requirements

Drug industrialization

requirements

Customized delivery device

Clinical Development (phase I, II, III) Approval

Devices customized to specific requirements of drugs and target patients

Collaboration with drug companies from clinical development through commercial sales

Unique devices increasingly used to differentiate brands, optimize product lifecycles and enhance patient care

Sales

New Paradigm in Drug-Device Development

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Summary

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Unilife - emerging global leader in innovative drug delivery devices

Injectable drug delivery device market is attractive and growing fast

Innovative, differentiated devices for pipeline drugs and biosimilars

Developing rich portfolio of technologies driven by customer need

Unifill: the 1st and only prefill syringe system with integrated safety

The new drug-device paradigm is to target pipeline drugs to develop total system solutions for the pharmaceutical partner

Launch with Unifill, then drive growth with successive introductions

of innovative, differentiated devices