Unesco Intangible Cultural Heritage of Humanity: Mediterranean … · 2015-11-17 · Applied...

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1 Department of Drug Science and Technology, School of Pharmacy, University of Torino, Via Pietro Giuria 9, 10125 Torino, Italy 2 Directorate General of Food Safety and Nutrition, Ministry of Health , Via G. Ribotta, 5, 00144 Rome, Italy Abstract: Keywords: INTRODUCTION Capitulare de villis vel curtis imperii Caroli Magni Hortus simplicium Unesco Intangible Cultural Heritage of Humanity: Mediterranean diet and Ethnobotanic knowledge

Transcript of Unesco Intangible Cultural Heritage of Humanity: Mediterranean … · 2015-11-17 · Applied...

Page 1: Unesco Intangible Cultural Heritage of Humanity: Mediterranean … · 2015-11-17 · Applied ethnobotany: people, wild plant use and conservation Ethnobotany : a methods manual Ethnobotanique

1 Department of Drug Science and Technology, School of Pharmacy, University of Torino, Via Pietro Giuria 9, 10125 Torino, Italy

2 Directorate General of Food Safety and Nutriti on, Ministry of Health , Via G. Ribotta, 5, 00144 Rome, Italy

Abstract:

Keywords:

INTRODUCTION

Capitulare de villis vel curtis imperii Caroli Magni

Hortus simplicium

Unesco Intangible Cultural Heritage of Humanity: Mediterranean diet and Ethnobotanic knowledge

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Convention for Safeguarding Intangible Cultural Herit age

knowledge and practices concerning nature and the universe

ethnobiology traditional knowledge

Ethnobotany: History and Methods for a Quantitative Ethnobotany

Homo sapiens

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etc.

Interpretation and meaning of plant secondary metabolism

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Figure 1 Primary and secondary metabolism reactions

chlorophyll + CO2 + light

Carbohydrates

Pentose cycle

Shikimic Acid

Aromatic amino acids

Cinnamic acid

PHENYLPROPANOIDS

Phosphoenolpyruvic acid

Pyruvic acid

Acetil CoenzimaA

Tricarboxylic acidsAmino acids

ALKALOIDS

Malonyl -CoA

FLAVONOIDSPHENOLS

Mevalonic acid

TERPENOIDSCAROTENOIDSSTEROIDS

etc

etc.

etc

etc.

why can the secondary metabolites (plant chemicals) affect human life ?

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etc.

etc.

The reverse pharmacology: a new approach on the basis of ethnobotanical data

Digitalis purpurea

An Account of the Foxglove and some of its Medical Uses

Galanthus

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etc.

Functional aspect of conventional food: innovative interpretation

etc

etc

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Figure 2 Comparison between Medical and Nutritional Pharmacology (from Migrating principles of pharmacogenomics (PGx) to nutrigenomics (NGx) to enable the practice of preemptive nutrition. [from Gillies & Krul (83)]

etc

de novo

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CONCLUSIONS

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Figure 3 The step-by-step scientific basis of ethnobotany

Traditional usage of food and health plants = Ethnobotany 1

Thousand of Phychemicals inside a single plant 2

Criteria for selecting plants for investigation: selection basedon traditional usage 3

Experimental approach by means of Reverse Pharmacology Method 4

In a Nutritional Pharmacological point of view, the classic plant-based foodcontains Phytochemicals, able to maintain the homeostasis in human subjects. The Phytochemicals exert their physiological effects on the basis ofxenohormetic phenomenon. 5

Summary of the steps demonstrating the scientific basis of the ethnobotany, directly linked with the xenohormesis, a biological phenomenon described ashomeostasis promoting factor.

REFERENCES J. Ethnopharmacol 92

J. Pharm. Pharmacol 53

Methods in Plant Biochemistry

Curr Protoc

Pharmacol

Pharmacol Ther 123

J. Ethnobiol. Ethnomedicine 6

Mediterr J Nutr Metab.

Public Health Nutr 1A Nutr Metab 2 Clin Nutr 23

J.Clin. Epidemiol. 60

Nutr. Metab. Cardiovasc. Dis20

Eur. J. Clin. Nutr. 45,

Arch. Gen. Psychiatry , 66

FASEB J. 21,

JAMA Am J Cardiol. 105

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Circulation 116

Nutr. Metab. Cardiovasc. Dis. 21

Intern. J.Epidemiol 37

Safeguarding of the Intangible Cultural Heritage.

2005

1908 Botanical Gazette 21 Ethnobot. Res. Appl 5,

J Ethnopharmacol 32 Economic Botany 47,

Economic Botany 47

Selected guidelines for ethnobotanical research: a field manual

Ethnobotany: principles and applications

Applied ethnobotany: people, wild plant use and conservation

Ethnobotany : a methods manual

Ethnobotanique générale

Monografias del Jardin Botánico de Córdoba 3

J. Ethnopharmacol

J. Ethnopharmacol. 81

Economic Botany 50

Taxon 50 Adv. Nutr. 2,

Ethnobotany: Evolution of a discipline

Selection, preparation and pharmacological evaluation of plant material

Trease and Evans’ Pharmacognosy

Drug Discovery Today 3 Science 129 Hum. Exp. Toxicol

21 EMBO (European Molecular Biology

Organization) reports 10

Cell Stress and Chaperones , 15 Cell 133

Malaria J., 10

An account of the foxglove and some of its medical uses: with practical remarks on dropsy and other diseases

Phytochem. Lett 1 Ind. J. Exp. Biol.

48

Chem. Res. Toxicol 20

Science 285 PNAS, 103 Alternative therapies 14 Phytochem. Rev. 7

Pharmacol. Res 55

Phytochem. Rev 7

J. Biomed. Biotechnol. 5 Pharmacol. Res 55

Exp. Biol. Med. 227

J.Natl. Cancer Inst. 99

Am. J. Cardiol.101

Nutr. Metab 7

Nutriti on Reviews 64 Pharmacol. Res 55

Chocolate and Health

Pharmacol. Res J Cardiovasc

Pharmacol 54

J. Nutr. 137 Biodiversity