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TNFORMATI PERSONALE

UNILA C. Aura-Midilina

Aura-Midilina VINTILA

Bd. Aviatorilor 34 -36, Sectoll , cod postal 01 1863, Bucuregti

021 317 2A 41:int288

madalina.vintila@yahoo.com

Sexul:Feminin

Data nagterii:30/1 0/1 983

Nationa litatea: Rom6ni

lnstitutul National de Endocrinologie "Cl Parhon" Bucuresti, Secfia EndocrinologiePediatricS- din Aprilie 2016

Medic specialist endocrinolog

Medic specialist endocrinologCompetenli ecografi e endocrini

Medic rezident endocrinolog

lnstitutul Na[ional de Endocrinologie,,Cl Parhon", Bd. Aviatorilor Nr. 34-36, Sector1, Bucuregti, www.parhon.roExaminarea pacientilor, completarea fisei de observatie, stabilirea investigatiilor (biologice,imagistice), stabilirea tratamentului medicamentos primit de pacienti, supraveghereapacientilor - sub indrumarea medicului coordonator.Stagii de pregitire clinici in spitale universitare din Bucuregti in medicini internS,cardiologie, nefrologie, neurologie, psihiatrie, terapie intensivS, genticd medicali, diabet gi

endocrinologie

2011 - prezentDoctorand - teza: ,,Rolul vasopresineiin fiziopatologia sindromului metabolic"Universitatea de Medicind si Farmacie,,Carol Davila" Bucuregti, DisciplinaEndocrinologie

2002 - 2008Doctor - MedicLucrare licenld: ,,Conduita obstetricali in prezentatia pelvianS" sus(inutd inSeptembrie 2008Universitatea de Medicind gi Farmacie,,Carol Davila" Bucuresti, Facultatea deMedicina GeneraldMedia 9.7/10, clasati pe pozitia 9/558 absolvenli1998 - 2002

Colegiul National,,Mihai Viteazul" Bucuregti

LOCUL DE MUNCA /DOMENIUL OCUPATIONAL

EXPERIENTAPROFESIONALA

01 lanuarie 2014

2009 - 2013

Loc de munca

Principalele activititi gi

responsabilitdti

EDUCATTE 9TFORMARE

PerioadaCalificarea

Numele gi tipul institu{iei

PerioadaCalificarea

Numele gi tipul institu[iei

PerioadaNumele 9i tipul institu{iei

J':1\ UNTTLA C. Aura-Midilina

2014,27-30 Noiembrie14tn ESE Postgraduate Course in Clinical Endocrinology, Cluj Napoca, RomAnia

2014, 12lunieTraining Good Clinical Practice, Accelsiors CRO

2013,24-25 lunieIOF-ISCD lnternationalCourse: Osteoporosis Essentials- Densitometry, Diagnosisand Management. Bucuregti, Rom6nia

2012,20-21 NoiembrieTraining Course in Bioinformatics:Data management and analysis for GWAS andlocus refining using Next Generation Sequencing (NGS) for MEDIGENE partners,Barcelona, Spania

2011,22-24 Septembrie11th ESE Postgraduate Course in Clinical Endocrinology, Belgrad, Serbia

CURSURI DEPERFECTIONARE

PerioadaCurs

PerioadaCurs

PerioadaCurs

PerioadaCurs

PerioadaCurs

Perioada 2007, AugustCurs Basic si Advanced Life Support - SMURD Tirgu-Mures, Rom6nia

BURSE,STAGII DE PREGATIRE iN

STRAINATATE

Perioada

Perioada

Perioada

ACTIVITATE DECERCETARE

Proiecte

2013, Noiembrie - 2014, MartieStagiu de pregdtire in tehnici de geneticdin Laboratorul de EndocrinologieMoleculari - lnstitut Universitaire de Recherche Clinique, UMR-204 Nutripass,Montpellier, Franla, sub coordonarea Prof. Florin Grigorescu, MD, PhD. Pregitirein tehnici de genotipare, introducere in tehnica next-generation sequencing,pregdtire in bioinformaticd si analizi statisticS2012, 9 lunieBursa ,,Grigore Coculescu" pentru Neuroendocrinologie, Poiana Brasov, Rominia- bursa pentru vizilEt (2 siptdm6ni) la lnstitut Universitaire de Recherche Clinique,UMR-204 Nutripass, Montpellier, Franfa, sub coordonarea Prof. Florin Grigorescu,MD, PhD, in vederea pregitirii cercetirii in cadrul doctoratulul2007 (Februarie - lulie)Bursa de studii Erasmus - Facultatea de Medicini Montpellier-Nimes,Universitatea Montpellier l, Montpellier, Franla. Stagii: Endocrinologie, Nefrologie,Urologie, Reumatologie, Ortopedie (medii 17 -19120)

2012- 2016Proiect de cercetare FP7 - MEDIGENE: Factorii genetici si de mediu aisindromului de rezistenta la insulina si complicatiile pe termen lung in populatiileemigrante ale Mediteranei (membru in echipa de cercetare)Autoritatea contractanti: Comisia Europeand (Research & lnnovation - Health)Contractor: UMF "Carol Davila" Bucuresti - partener intr-un consortiu internationalformat din 17 centre, prin grupul roman de cercetare coordonat de Prof. Dr. MihaiCoculescu

VINTLA C. Aura-Midilina

2014- 2016Subinvestigator in: Studiu multicentric CP-4-005, in faza a lll-a, pentru evaluareaeficacititii 9i siguran{ei produsului hGH cu acliune indelungat5 (MOD-4023) la

subiec(ii adutli cu deficienli a hormonului de crestere

Endocrine Society din 2016Societatea RomAnd de Endocrinologie din 2016British Society for Endocrinology din 20'12

European Society of Endocrinology din 2011

Societatea RomAnd de Psihoneurendocrinologie din 2009

StudiiClinice

AFILIERI

COMPETENTEPERSONALE

Limba maternd RomAna

Alte limbi strdine cunoscute

Englezd

FranceziSpaniolS

Competente de comunicare

Competen{e informatlce

Permis de conducere

inremorRE

Ascultare Citire

VORBIT SCRIS

Participare la

conversalie8282

B1

Niveluri: 41/2: Utilizatorelemenlar-c_l12: Utilizatorindependent-C1/2: Utilizatorexperimentat

Cadrul european comun de referinld pentru limbi strdine

Bune competenle de comunicare si spirit de echipS, capacitate de adaptare la mediu

intercultural.

Microsoft OfiicerM, StatView Haploview

Categoria B

Discurs oral

82B2

B1

82B2

B1

a2B2

B1

8282B1

INFORMATIISUPLIMENTARE

Publicatii 1.

.ri

Vintili M, Gheorghiu ML, CaragheorgheopolA, Baculescu N, Lichiardopol C, Badiu

C, Coculescu M, Grigorescu F, Poiand C. lncreased copeptin levels in metabolic

syndrome from a Romanian population. Journal of Medicine and Life, Vol 9, lssue 4,

Oct-Dec 2016, 353-357.

Vintili M, Coculescu M, Grigorescu F, Poiana C. The Vasopressin System in

Metabolic Syndrome and lnsulin Resistance - a Mini-Review. Modern Medicine 2016,

Vol. 23, No. 3, 232-238Gheorghiu ML, Gdloiu S, Vintili M, Purice M, Hortopan D, Dumitragcu A, Coculescu

M, Poiand C. Beneficial effect of dose escalation and surgical debulking in patients

with acromegaly treated with somatostatin analogs in a Romanian teftiary care

center. Hormones (Athens). 2016Apr; 15(2):224-34- doi: 10.14310|horm2402.1675.

CostacheOutas M, Vintila M, Caragheorgheopol A, Dumitrescu C, Costache CR,

Procopiuc C. Management of Growth Promoting Therapy Using Height Velocity

Prediction Models in Turner Syndrome. Cunent Health Sciences Journal, 2015, Vol

41, Suppl. 5, 143 - 146.Mntila M, Costache-Outas M, Caragheorgheopol A, Dumitrascu A, Procopiuc C.

Long Time Follow-Up ls Mandatory ln Successfully Surgically Cured Pediatric

2.

3.

4.

5.

l ll ir'rlr"l.:i, ii i r '.,r:llil:l MNflLA C. Aura-Midilina

Cushing's Disease - Case Reports. Cunent Health Sciences Journal, 2015, Vol 41,Suppl. 5, 139 - 142,

6. Attaoua R, Boeckler N, Radian S, Ait El Mkadem S, Poucheret P, Lataoie VGheorghiu M, Fica S, Mntili M, Normand C, Coculescu M, Grigorescu F. Densemapping of the region of insulin gene VNTR in polycystic ovary syndrome in apopulation of women from Central Europe. Endokrynol Pol. 2015; 66(3):198-206. doi:10.5603/EP.2015.0026

7. Mntili M. Diabetology in ClinicalResearch. Acta Endo (Buc) 2015 11: 132-133 doi:1 0,41 831 aeb.20 1 5.'l 32

8. Ben salem A, Attaoua R, Mtiraoui N, Belkahla $, Fzzidi l, Ajina M, Souissi M,Poucheret P, Vintili M, Grigorescu F, Mahjoub T. Common polymorphisms ofcalpain-10 and the risk of polycystic ovary syndrome in Tunisian population: a case.control study.Mol Biol Rep. 2014 Od;41(10):6569-74.

9. Vintili M. Actualities in Medicine. Thyroid Management in Pregnancy and News inFrequent Diseases. Acta Endo (Buc) 2013 9: 331-336 doi: 10.4183/aeb.2013.331

10. Vintili M. Actualities in Medicine. Acta Endo (Buc) 2012 8: 511-515 doi:10.41831aeb.2012.511

Comuniciri orale 1. A. Cirla, C. Dumitrescu, I Gherlan, A. Brehar, A. Caragheorgheopol, S Vladoiu, M.Vintili, O. Popa, C. Procopiuc. Congenital adrenal hyperplasia - a S-yearretrospective study in a tertiary center of paediatric endocrinology. 11th Congress ofRomanian Association of Clinical Endocrinology, 21-24 September 2016, Craiova,Romania

2. C. Procopiuc, M- Vintild, C. Dumitrescu, A. Dumitrascu, L Gherlan. ProgressiveOsseous Heteroplasia in a Child with Pseudohypoparathyroidism type IA. CommonCongress of the Romanian Society of Endocrinology and RomanianPsychoneuroendocrine Society, 23-25 June 2016, Brasov Romania

3. Monica Gheorghiu, Midilina Vintili, Florin Grigorescu Metabolic syndrome inRomania: specificities on hyperandrogenic women. Final MEDIGENE Meeting, 3-5June 2016, Montpellier, France

4. Sara Haydar, Redha Attaoua, Jean Frederic Brun, Nicoleta Baculescu, MidilinaVintili, Stephanie Badiou, Mihai Coculescu, Jean Paul Cristol, Florin Grigorescu.Mapping of genes involved in BCAA metabolism indicates association with insulinresistance in French and Romanian populations. 4th Annual meeting ofM EDIGEN E, 26-28November, 20 1 5, Zagreb, Croatia

5. Nicoleta Baculescu, Florin Grigorescu, Midilina Vintili, Mihai Coculescu. Forensicmarkers for premature male baldness (PMB) tested in women population areassociated with PCOS. 4th Annual meeting of MEDIGENE,26-28 November 2015,Zagreb, Croatia

6. Midilina Vintili, Diana Paun, Carmen Georgescu, Monica Gheorghiu, MihaiCoculescu, Redha Attaoua, Florin Grigorescu and MEDIGENE consortium. Geneticmarkers identified inmetabolic syndrome in Romanian population. 4th Annual meetingof MEDIGEN E, 2F28 November 20 1 5, Zagreb, Croatia

7. Sara Haydar, Redha Attaoua, Mihai Coculescu, Mddilina Vintili, ChristopheNormand, Nicoleta Baculescu, Florin Grigorescu. PPMIK (protein phosphatase,Mg2+/Mn2+dependent, 1K) Gene Association in Polycystic Ovary Syndrome forBetter Understanding ofthe Role of Branched-Chain Aminoacids Variation inMetabolic Disorders. CBS2 Day, IGH Genopolys, Campus Arnauld de Villeneuve,27th May, Montpellier, France

8. Midilina VintilS, Redha Attaoua, Nicoleta Baculescu, Monica Gheorghiu, FlorinGrigorescu, Mihai Coculescu & MEDIGENE Consortium. Pre-Screening of MetabolicSyndrome Genes in PCOS Population in Romania. MEDIGENE Annual Meeting,27h February - 1st March 2014, Casablanca, Morocco

L Midilina Vintili, Mihail Coculescu, Florin Grigorescu. Genetic variation of AVPIareceptor in Romanian women with PCOS and metabolic syndrome. RomanianCongres of Psychoneuroendocrinology, 30 May - 1 June, 2013, Sibiu, Romania

10. Midilina Vintili, Nicoleta Baculescu, Redha Attaoua, Florin Grigorescu, MihaiCoculescu. lntroducing next generation sequencing in WP3: candidate loci (genes)

VINTILA C. Aura-Middlina

for PCOS and/or MetS (preliminary results). MEDIGENE Annual Meeting, 19-20 April

2013, Poiana Brasov, Romania11. M Vintil, M Coculescu, F Grigorescu. Genetic variations ofarginine vasopressin -

AVPIa receptor complex in metabolic syndrome. MEDTGENE Bucharest Meeting,Hotel Novotel, 15h December 2012, Bucharest, Romania.

12. Gheorghiu ML, Vintili M, Purice M, Hortopan D, Dumitrascu A, Poiana C, CoculescuM. Efficacy of somatostatin analogs as first-line versus postoperative treatment in

acromegaly. The 20m National Congress of Endocrinology with lnternational

Speakers, 27-29 September 2012, Sinaia, Romania (abstract p. 1 3)

13. Gheorghiu ML, Vintili M, Baciu l, Radlan S, Poiana C, Badiu C, Coculescu M.

Hype(ension in incidentally discovered oligosymptomatic phaeochromoc$omas.

ENSAT Symposium - Adrenal Tumors and Hypertension, 7-8 June 2012, Poiana

Brasov, Romania (abstract p. 63)

14. Gheorghiu ML, Ciubotaru V, Anghel R, Ciurea AV Vintili M, Banaru A, Niculae A,

Purice M, Dumitrascu A, Hortopan D, Poiana C, Badiu C, Coculescu M. Treatmentefiicacy in acromegaly - a 2}-year experience of a tertiary care neuroendocrinologycenter. The 19tn National Congress of Endocrinology with lntemational Speakers, 6 -8

October 2011, Bucharest, Romania (abstract p. 20)

15. Badiu C, Caragheorgheopol A, VintilS M, Silvestro L. Advantages of mass

spectroscopy a"-.rys -for

steroid hormones in clinical practice. Tfre XVtth National

Congress of Endocrinology with lntemational Participation, 29-31 October 2009,

Sinaia, Romania (abstract P. 86)

Prezentiiriposter 1. F Grigorescu, N Baculescu, M Mntila, M Gheorghiu, M Coculescu. Locus refining ofAndrogen Receptor (AR) gene using MEDISCOPE Gene Chip indicates strong

association to polycystic ovary syndrome (PCOS) in Romanian and Meditenaneanpopulations. ENDO2016, 1-4 April 2016, Boston, USA doi: 10.1210/endo-

meetings.201 6.RE.5.SUN-1 39 P2. Mariana-Cristina Costache.Outas, Camelia Procopiuc, Oana Popa, Madalina-Aura

Vintili, Cosmina-Raluca Costache, Danai Stambouli.A rare form genetic abnormality

in Tumer syndrome. Society for Endocrinology BES Meeting, 2-4 November 2015,Edinburgh, United Kingdom

3. S. Haydar, R. Attaoua, N. Baculescu, M Coculescu, M Vintild, A, Ben Salem, C.

Normand, F Grigorescu. Association du gene IVD avec des

alterations m6taboliques dans lesyndrome des ovaries polykystiquespermet une meilleur conpr6hension du role des aminoacides

branches dans l'insulino-r6sistance. Annual Congress of SFE,7-10October, 2015, Angers, France

4. Redha Attaoua, Sarah Haydar, Doaa Fakih, Lykke Andreasen, Midilina VintilS,Assila Bensalem, Nicoleta Baculescu, Christophe Normand, Patrick Poucheret, Mihai

Coculescu, Florin Grigorescu. Genes previously associated with polycystic ovary

syndrome (PCOS) in the Asian population: variability in a population with PCOS from

Central Europe. Annual Meeting of EASD, 14-18 September, 2015, Stockholm,

Sweden5. Haidar S, Attaoua R, Coculescu M, Mntili M, Ben Salem A, Baculescu N, Poucheret

P, Grigorescu F. Haplotype mapping of GCKR gene indicates the association with

PCOS andreveals the role of BCAA metabolism. Annual Meeting of EASD, 14-18

Septembet 2015, Stockholm, Sweden6. Attaoua R, Coculescu M, Normand C, Haydar S, Fakih D, Vintila M, Muraru S,

Baculescu N, Cazaledes D, Poucheret f Grigorescu F. Locus Refining of the FTO

Gene at Density of1000 Genome Project and Haplotyping Allow a Better

Understanding of the Gene Associationin Complex Disorders. 75th Scientifc session

ofADA, 5-9 June 2015, Boston, USA7. Coculescu M, Vintili M. Two treatment patterns of thyrotropinomas with over 3-year

follow-up. 17th European Congress of Endocrinology, 16 - 20 May 2015, Dublin,

lreland.8. Coculescu M, Vintili M, Attaoua R, Baculescu N, Gheorghiu M, Grigorescu F.

lnteraction Between C-Reactive Protein snd Fat Mass and Obesity Genes Better

Explains lnsulin Resistance in Polycystic Ovary Syndrome in Romanian Population.

i.ll rli lr":ilil ;li:'r'!'t Ii:t,r UNILA C. Aura-Midilina

16th lnternational Congress of Endocrinology, 21-24 June 2014, Chicago, USA.

doil A I 21 0 I endo-meetings.20'1 4. RE. 1 3. MON-00709. Grigorescu F, Attaoua R, Vintila M, Baculescu N, Gheorghiu M, Radian S,

Normand C, Poucheret fl Coculescu M. Haplotype Mapping Reinforces the StrongInfluential Role of DUSP9 Gene in Metabolic Complications of Polycystic OvarySyndrome. American Diabetes Association Meeting, 13-17 June 2014, SanFrancisco, USA.

10. Vintili M, Attaoua R, Grigorescu E Coculescu M. Genetic variant of AVPR1Ageneassociated with metabolic syndrome elements in Romanian women with polycystic

ovary syndrome. Annual Congress of the Romanian Medical Association, 10-12 April2014, Bucharest, Romania.

11. Grigorescu F, Attaoua R, Fakih D, Poucheret P, Mntili M, Baculescu N, Renard E,

Coculescu M. Strong association of DUSP9 gene among 16 candidates withmetabolic syndrome in hyperandrogenic women. lntemational Symposium of lnsulinReceptor and lnsulin Action, November 201 3, Barcelona, Spain

12. ML Gheorghiu, M. Mntili, M.Purice, C. Poiana, M. Coculescu. Short-term (3 months)compared to long-term response to somatostatin analogues in acromegaly. Societyfor Endocrinology BES Meeting, 18 - 21 March 201 3, Hanogate, United Kingdom

13. Gheorghiu ML, Vintili M, Ciubotaru V Ciurea AV Purice M, Dumitriu E, DumitrascuA, Hortopan D, Badiu C, Poiana C, Coculescu M. Cure rate of acromegaly aftertranssphenoidal pituitary surgery* the 20 years experience of the Department ofNeuroendocrinology of ,,C.1. Parhon" lnstitute. The 19"' National Congress ofEndocrinology with lnternational Speakers, 6 - 8 October 2011, Bucharest, Romania(abstract p. 52)

14. JercilSu S, Mntili M, Stinescu B, Badiu C. Subacute onset of Riedelthyroiditis andhypoparathyroidism. The XVllh National Symposium of Psychoneuroendocrinology,26-28 May 2011, Bucharest, Romania

15. Badiu C, JercilSu S, Mntili M, Gdvan V Dobrescu R, Tomulescu V Beuran M,

Stefdnescu AM. lmpact of surgery upon metabolic profile in a case series ofpheochromocytomas. The XVllm National Symposium of Psychoneuroendocrinology,26-28 May 201'1, Bucharest, Romania

16. Vezea S, Vintild M, Badiu C. Limits of therapy in agressive GH secreting tumors in

adolescents. The XVllth National Congress of Endocrinology with lntemationalParticipation, 29-31 October 2009, Sinaia, Romania (abstract p. 115)

'17. Vintild M, Vezea S, Badiu C. Management in a case series of gastroentero-pancreatic NET. The XVllth National Congress of Endocrinology with lnternationalParticipation, 29-31 October 2009, Sinaia, Romania (abstract p. 113)

18. Mntili M, Vladdreanu AM, Miron R, Badiu C. Antiphospholipid syndrome in Gravesdisease. The lVth National Congress of Neuroendocrinology wtth lnternationalParticipation, 2*28May 2009, Bucharest, Romania (abstract p. 102)

19. Vintild M, \fizireanu A, Miron R, Badiu C. Beyond hypothalamic mass - casepresentation. The lVe National Congress of Neuroendocrinology with lntemationalPartrcipation, 2*28 May 2009, Bucharest, Romania (abstract p. 76)

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