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Peaceful Measures. Canada's Way Out of the 'Waron Drugs.' Brucc K. Alexander. University of TorontoPress, Buffalo, NY, 1990. xiv, 401 pp., illus. Paper,$19.95.

Pearls in Graph Theory. A Comprehensive Intro-duction. Nora Hartsfield and Gerhard Ringel. AcademicPress, San Diego, CA, 1990. x, 246 pp., illus. $29.95.

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Psychoanalytic Knowledge. Eugene B. Brody. In-ternational Universities Press, Madison, CT, 1990. vi,246 pp. $30.

Radiolabelled Cellular Blood Elements. HelmutSinzinger and Mathew L. Thakur, Eds. Wiley, NewYork, 1990. xxiv, 379 pp., illus. $98. Progress in Clinicaland Biological Research, vol. 355. From a symposium,Vienna, Sept. 1989.Realism with a Human Face. Hilary Putnam. James

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Representation Theory and Automorphic Func-tions. I. M. Gel'fand, M. I. Graev, and I. I. Pyatetskii-Shapiro. Academic Press, San Diego, CA, 1990. xviii,426 pp. Paper, $39.50. Generalized Functions, vol. 6.Translated from the Russian edition by K. A. Hirsch.Repint, 1968 ed.Reproductive Pathology of Domestic Mammals.

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Robotics in Science. Joseph F. Engelberger. MITPress, Cambridge, MA, 1989. 248 pp., iUus. $37.50.Rocky Mountain Spotted Fever.Uistory ofa Twen-

tieth-Century Disease. Victoria A. Harden. Johns Hop-kins University Press, Baltimore, MD, 1990. xvi, 375pp., illus. $39.50. Henry E. Sigerist Series in the Historyof Medicine.ScientMc Engineering Research Facilitles at Uni-

versities and Colieges. 1990. National Science Foun-dation, Washington, DC, 1990. xxii, variously paged,illus. Paper.

Sclentffic Visualization and Graphics Stimulation.Daniel Thalmann, Ed. Wiley, New York, 1990. x, 264pp., illus. $49.95. From a series of lectures, Lausanne,Switzerland.Seabirds of Hawaii. Natural History and Conserva-

tion. Craig S. Harrison. Comstock (Cornell UniversityPress), Ithaca, NY, 1990. x, 249 pp., illus., + plates.$36.50; paper, $15.95.Sea-Level Change. Geophysics Study Committee.

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Site Unseen. The Politics of Siting a Nudear WasteRepository. Gerald Jacob. University of PittsburghPress, Pittsburgh, PA, 1990. xxii, 234 pp., illus. $29.95.Pitt Series in Policy and Institutional Studies.Sixty-Two Years of Uncertainty. Historical, Philo-

sophical, and Physical Inquirics into the Foundations ofQuantum Mechanics. Arthur I. Miller, Ed. Plenum, NewYork, 1990. viii, 316 pp., illus. NATO Advanced ScicnceInstitutes Serics, vol. 226. From a course, Sicily, Italy,

lid State Microbatteries. James R. Akridge andMinko Balkanski, Eds. Plenum, New York, 1990. x, 439pp., illus. $95. NATO Advanced Sceicen Institutes Se-ries, vol. 217. From a course, Sicily, Italy, July 1988.Somatotyping. Development and Applications. J. E.

Lindsay Carter and Barbara Honeyman Heath. Cam-bridgc Univcrsity Press, Ncw York, 1990. xiv, 503 pp.,illus. $125. Cambridge Studies in Biological Anthropol-ogy) 5.

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York Acaderny of Sciences, Ncw York, 1990. xiv, 489pp., illus. Cloth or paper, $100. Annals ofthe New YorkAcademy of Sciences, vol. 595. From a symposium,Taormina, Italy, Mar. 1989.

StochastIc Flows and Sto c DferentlalEquations. Hiroshi Kunita. Cambridge UnivcrsityPress, Ncw York, 1990. xiv, 346 pp. $69.50. CambridgeStudics in Advanced Madtmatics, 24.

Stratlfiction of Tropical Forests as Seen In LeafStructure. Part 2. B. Rolkt, C. H. Hogermann, and I.

Roth. Kluwer, Boston, 1990. xvi, 246 pp., illus. $160.Tasks for Vcgetation Scicnce, 21.

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Frontiers in Basic Sciences That Relate toHeart, Lung, and Blood Diseases Symposium:

Molecular and Cellular Biology ofCystic Fibrosis:Basic Concepts and Strategies for New Therapies

February 21-22, 1991Masur AuditoriumNational Institutes of HealthBethesda, Maryland

Sponsored by TheNational Heart, Lung, andBlood Institute (NHLBI) andThe Cystic Fibrosis Foundation

The symposium is the sixteenth in the series of "Frontier in Basic Sciences ThatRelate to Heart, Lung, and Blood Diseases:' This series is conducted byNHLBIto capitalize on and transfer the progress achieved in basic science disciplines toclinical research progams. Through the pursuit ofnew knowledge concening thefundamental aspects of the life processes relating to heart, lung, and blooddiseases, it is hoped that better approaches to disease prevention and control willbe discovered. At this symposium, leading rsearchers and apertsin the field willpresent their views on the state of the science, the problems facing currentunderstanding, and anticipated future developments in the research of cystcfibrosis.

The symposium will be chaired by Dr. Ronald G. Crystal of the National Heart,Lung, and Blood Institute, Bethesda, Maryland, Dr. Arthur Beaudet of BaylorCollege of Medicine, Houston, bTas, and Dr. William B. Guggino ofThe JohnsHopkins University, Baltimore, Maryland. Presentations willbe structuredaround the following topics: the cystc fibrosis gene; the normal and cystic fibrosisphenotype; and strategies for new therapies. Presentations by noted experts will befollowed by open discussion.

The speakers are Arthur Beaudet, Richard C. Boucher, Francis S. Collins, RonaldG. Crystal, Raymond A. Frizzell, Alfred G. Gilman, William B. Guggino,Christopher Higgins, GeraldR Pier, John R. Riordan, Steven Shak, Alan E.Smith, Lap-Chee Tsui, Michael Welsh.

For further information and registmion materials, please contact:Ms. Gealdine Wolfe Office of Program Planning and Evaluation, NationalHeart, Lung, and Blood Institute, National Institutes of Health, Building 31,Room 5A06, Bethesda, Maryland 20892, (301) 496-9899.

30 NOVEMBER 1990

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DISPLAY PERSONNEL ADVERTISEMENTSFor rates, deadlines, and information about fractionaldisplay ads (1/6 page and larger) and all Marketplacolistings of available products and services, contact:

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RESPONSES TO EMPLOYMENT ADSApplicants should read Positions Open ads carefully inorder to submit all required material when responding,and should especially check for any stated deadline forreceipt of applications. SCIENCE encourages appli-cants for positions to investigate employment laws, non-discrimination pdicies, visa requirements, and culturaldifferences in the country advertising for employees.To reply to a blind box ad, address correspondence to:

Box (give number)SCIENCE ClasId AdvetsIng1333 H Stre, NW, Room 940

WashIngton, DC 20005

POSITIONS OPEN

Colby Coliege invites applications for a 1-year, sabbat-ical leave replacement position (1991-92) as ASSIST-ANT PROFESSOR OF BIOLOGY. Candidatesshould have a Ph.D., experience with and a strongcommitment to teaching undergraduates, broad trainingin the biological sciences, and special interests and train-ing in genetics, animal behavior, and animal biology.Familiarity with liberal arts colleges and/or postdoctoraltraining are desirable. Responsibilities will indude teach-.ing an upper-level course in genetics and one in animalbehavior, and a segment of our introductory biologycourse that deals with animal biology. Submit letter ofapplication, statement of teaching and research interests,curriculum vitae, reprints of publications, undergraduateand graduate transcripts, and three letters from individ-

ualsfamiliar with the applicants teaching and/or researchto: Professor Ahur L Champlin, Chair, Depart-ment of Biology, Colby College, Watervilie, ME04901. Applications should be complete by 17 Decem-ber 1990. Colby College is an Affirmative Action/EqualOpportunity Employer and strongly encourages applicationsfrom women and minoritis.

ENVIRONMENTAL BIOLOGIST/ECOLOGISTASSISTANT PROFESSOR. Tenure track. Respon-

sibilities include teaching general biology and upperdivision courses in hisher specialty. Ph.D. required,appropriate visa status ifapplicable, commitment to under-graduate teaching and research; teaching experience pre-d. Qualied minority candidates are encouraged to apply.

Send curriculum vitae, transcripts, and letters from threereferences to: Search Committee, Department of Bi-ology., Purdu University Calumet, Hammond, IN46323. Purdue Calumet is an Equal Opportunity/Affirma-tive Action Employer. Closing date: 18 January 1991.

UNIVERSITY OF OTTAWADEPARTMENT OF PHARMACOLOGY

A tenure-track ASSISTANT PROFESSOR POSI-TION is available for candidates with a background inpharmacology. The successful candidate will have aPh.D. or equivalent degree, at least 2 years of postdoc-tora experience, and a strong commitment to researchand teaching. Preference will be given to candidates witha molecularbiology approach to research. Major researchinterests of the department include neuropharmacology,immunopharmacology, cardiovascular pharmacology,endocrine pharmacology, and toxicology. The depart-ment has teaching responsibilities for medical, nursing,and undergraduate students as well as graduate studentsin the M.Sc. and Ph.D. programs. Knowledge of Frenchis an asset. Applications, which must include curriculumvitae, three letters ofrecommendation, a briefdescriptionof research and teaching experience, a statement ofcareerobjectives, and an outline of proo research, shouldbe sent to: Dr. J.-M. Trifaro, Chima Departmentof Pharmacology, Faculty of Medicine, University ofOttawa, 451 Smyth Road, Ottawa, Ontario, Canada,K1H 8M5. The closing date for applications is 31January 1991.

In accordance with Canadian immigration requirementspriority will be given to Canadian citize and permanentresidents ofCanada.

ASSISTANT PROFESSORNEUROPHARMACOLOGY

Applications are invited for a tenure-track positionavailable in 1991 at the assistant professor level in theDepartment ofPharmacology at the University ofRoch-ester. Because the candidate would be expected to inter-act with faculty in the departmental Experimental Ther-apeutics Unit, whose focus is neurodegenerative diseases,we seek applicants who address fundamental questions inneuropharmacology and who are interested in the phar-macology of neurodegenerative diseases. Applicantsmust have a Ph.D. or M.D. degree, or both, 2 years ofpostdoctoral experience, the potential to develop andmaintain an independent research program, and an inter-est in professional and graduate education. Applicantsshould send their curriculum vitae, the names of at leastthree references, and a description of their present andfuture research interests to: Experimental TherapeuticsSearch Committee, Department of Ph cologyUniversity of Rochester, 601 Elmwood Avenue,Rochester, NY 14642. Applications will be receiveduntil 31 December 1990 or until the position is filled.7he University ofRohester is an Affirmative Action/EqualOpportunity Employer. Women and minorities are encour-aged to apply.

POSITIONS OPEN

TENURE-TRACK ASSISTANT PROFESSORMARINE GEOLOGY AND GEOPHYSICS

The School ofOceanography invites applications for atenure-track position at the assistant professor level tocomplement our existing interdisciplinary program onmid-ocean ridge processes. Applicants should be highlyqualified in quantitative modeling of processes involvedin the creation and early development of oceanic litho-sphere and demonstrate an interest in the dynanics oftheupper mantle, the processes associated with the extrac-tion of melt from the mantle, the thermo-mechanicalp of the lithos here, and physical processes in

S mhcsystems. successtl candidate will beexpected to have a strong commitment to sea-goingresearch and to develop a strong research program thatintegrates a wide range ofobservational and experimentaldata. In addition, teaching at the undergraduate andgraduate levels, as well as supervision of graduate stu-dents, will be an integral responsibility. Closing date forapplications is 15 January 1991. Applicants should sendcurriculum vitae, a statement of research interest, a list ofpublications, recent reprints, and the names of fourreferences to: Prof*ssor A. R. M. Nowell, Director,School of Oceanography, WB-10, University ofWashigon, Scattle, WA 98195. The University ofWashington is an Equal Opportunity/Affirnative ActionEmployer.

CELL BIOLOGY

A tenure-track appointment at the ASSISTANTPROFESSOR levef is available as of September 1991.Qualifications include a Ph.D. and postdoctoral experi-ence. The successful candidate will be expected to teachundergraduate courses in cell biology, either develop-mental biology or genetics; teach general biology; devel-op graduate courses in his/her area of expertise; andparticipate in our genetic engineering option. Training ofgraduate students at the M.S. level and ability to developan externally fundable research program are ex d.Search will continue until position is filled. Please sendyour curriculum vitae, transcripts, reprints, statement ofteaching interests and experience, research plans, andthree letters of reference to: Southern Illinois Univer-sity at Edwardsville (SIUE), Biological Sciences De-partment, Box 1651, Edwardsville, IL 62026-1651.Attention: Search Committee. SIUE is an AffinnativeAction Employer.

THE UNIVERSITY OF CALIFORNIALOS ANGELES (UCLA)

BIOLOGICAL CHEMISTRYASSISTANT PROFESSOR

The Department ofBiological Chemistry in the SchoolofMedicine at the University of California, Los Angeles,has an opening for an assistant professor (tenure track) tobe filled ineither 1991 or 1992. Outstanding candidateswith resercrh interests in any area of molecular, cellular,or developmental biology; biochemistry; or genetics areencouraged to apply. Completed applications consistingof curriculum vitae, a one-eagc summary of researchplans, and the names and add of three referencesshould be sent to:

Thc Search CommitteeDepartment of Biological Chemistry

UCIA School of MedicineLos Angeles, CA 90024-1737

FAX: 213-206-5272The University of Caltfornia is an Equal Opportunity

Employer. Applicationsfiom women and members ofminor-ity groups are strongly encouraged.

BIOCHEMIST. Tenure-track ASSISTANT PRO-FESSORSHIP beginning September 1991 in A.C.S.-approved chemistry department at Randolph-MaconCollege, a small cocducational liberal-arts college 20miles north ofRichmond, Virgnia. Candidate must havePh.D. in biochemistry or related discipline and showevidence ofcommitment to undergraduate education andresearch. Responsibility for biochemistry courses and fordeveloping a course in molecular biology; ability to teachorganic chemistry highly desirable. Teaching load of 24contact hours per academic year. Randolph-Macon is anEqual Opportunity Employer. Letter of application, briefdescriptions of teaching philosophy and research plans,curriculum vitae, and three letters of recommnmust reach us by 31 December 1990. Send to: Dr. BrianW. Moores, Chair, Department of Chemistry, Ran-dolph-Macon College, Ashland, VA 23005.

PERSONNEL PLACEMENT 128930 NOVEMBER 1990

POSITIONS OPEN

ASSISTANT PROFESSOR, BIOLOGY. MountSaint Mary's College (MSMC). Applications invited for atenure-track faculty position startng August 1991, fromrecent Ph.D.'s dedicated to quality teaching at a Catholicliberal arts college. All areas considered. Duties mayinclude introductory biology, upper level courses, non-majors biology, and undergraduate research. Competi-tive academic year salary. Send cover letter, curriculumvitae, undergraduate and graduate transcripts, three let-ters of recommendation, and outlines of research inter-ests and instructional strategies to: Dr. Robert Rich-man, Department of Science, Mount Saint Mary'sColiege, Emmitsburg, MD 21727, by 14 January1991. MSMC does not discriminate on the basis ofsex, age,race, or national origin.

ASSISTANT PROFESSOR, PLANT DEVELOP-MENTAL BIOLOGY. We seek applications for atenure-track position in the area of pnt development.Applicants must have received traing in whole plantstructure and anatomy and must have an establishedresearch program focusing on plant development. Pref-erence will be given to applicants whose research caninterface with the research activities of current faculty.Teaching responsibilities will include a course coveringbasic and contemporary aspects of plant anatomy andparticipation in an undergraduate majors course in de-velopmental biology. Applicants are expected to have aPh.D. in botany or other appropriate fiefd ofbiology andmust have a strong commitment to excellence in research,graduate trainig, and teaching. Applicants should sub-mit the following before 15 January 1991: curriculumvitae; copies of recent publications, grant applications,and/or manuscripts; a statement of research interests,goals, and current research activities; a description ofteaching philosophy and experience; and at least threeletters of reference to: Dr. Craig Martin, Chair, SearchCommittee, Department of Botany, Haworth Hail,University of Kansas, Lawrence, KS 66045-2106.Telephone: 913.864-3645. The University ofKansas isan Equal Opportunity/Afrmative Action Employer.

ASSISTANT PROFESSORSHIPS, BOTANYApplications are invited for two entry-level, tenure-

track positions in botany: (i) plant ecology and (ii) plantmorpholoy. For each position a strong commitment toexcellence in teaching and the development of an activeexternally funded research program will be expected.Curriculum vitae, copies of relevant publications, officialgraduate and undergraduate transcripts, and at least three[etters of recommendation should be received by 15January 1991 by: Dr. David E. Lemke, Department ofBiology, Southwest Texas State University, San Mar-cos, TX 78666-4616. Equal Opportunity/AffirmativeAction Employer.

ASSISTANT PROFESSOR. A new position willbecome available in January 1991 for a qualified individ-ual who has demonstrated ability to conduct productivebasic research in one of the following areas of rumorimmunology: membrane structure and function, controlof gene expression, cytolytic mechanisms. Minimal qual-ification will include Ph.D. or M.D. degree with post-doctoral experience. Applications consisting of curricu-lum vitae, a summary of research accomplishments,reprints of three selected publications, and three letters ofr*efrence should be sent to: Dr. Eva Lotzovi, Chief,Section ofNatural Immunity, Department of GeneralSurgery, The University of Texas, M.D. AndersonCancer Center, 1515 Holcombe Boulevard, Box 18,Houston, TX 77030. We are an Equal OpportunitylAffirmative Action Employer.

MOLECULAR PLANT PHYSIOLOGIST, AS-SISTANT PROFESSOR. The Biology Department atHobart and William Smith Colleges invites applicationsfor a tenure-track position in molecular plant physiology,effective 1 July 1991. Teaching responsibilities includeplant physiology, molecular biology, and a course in thecandidate's specialty, as well as participation in thecolleges' general curriculum. Qualifications include aPh.D. and a desire to involve undergraduates in research.A new science facility is in development. Applicationsmust indude curriculum vitae, statements of teachingand scholarship goals, all transcripts, and three letters ofrecommendation. The closing date for applications is 11January 1991. Send to: Dr. Valerie M. Kish, BiologyDepartment, Hobart and Wdlliam Smith Colieges,Geneva, NY 14456. Equal Opportunity/AffirmativeActionEmployer.

POSITIONS OPEN

SYSTEMATIC MAMMALOGIST. Tenure-trackASSISTANT PROFESSOR beginning fall semester1991. Ph.D. (ABD considered); experienced teaching.To teach mammalogy, wildlife conservation, and intro-ductory courses. Send curriculum vitae, transcripts of allcollege work, and three recommendation letters to:David Castaner, Biology Department, Central Mis-souri Statc University, Warrensburg, MO 64093-5053. Considerations begin 26 December 1990 and willcontinue until a suitable candidate is selected. AffirmativeAction/Equal Opportunity Employer. Women and minoritiesencouraged to apply.

SYSTEMIC ZOOLOGIST, ASSISTANT PRO-FESSOR. Tenure-track, fall 1991. Ph.D. required. Pref-erence given to applicants with a combination of fieldand molecular ainig and interests. To teach introduc-tory organismal biology, an advanced course in specialty,participate in college-wide programs and develop re-search program involving students. Send curriculumvitae, transcripts, and three letters of reference by 31January 1991 to: Dr. David Jordan, Vice President forAcademic Affairs, Austin College, Sherman, TX75091-1177.

MIAMI UNIVERSITYThe Department of Zoology at Miami University

intends to make two tenure-track appointments at the

ASSISTANT PROFESSOR level on the Oxford Cam-pus effective August 1991. We are seeking a molecularbiologist with a Ph.D. whose training is in developmen-tal biology and/or genetics, and who is interested in bothteaching and research. Duties include teaching graduateand undergraduate courses in a new interdepartmentalprogram in molecular biology and biotechnology. Wealso are seeking a developmental biologist with a Ph.D.whose taining is at the cell or molecular level, and whois interested m both teaching and research. Teachingduties include on a rotational basis courses in develop-mental biology and in the introductory program. Thesuccessfil applicants are expected to develop an activeresearch program and to seek external funding for it.Application review will begin 15 January 1991. Specifythe position(s) in which you are interested, and send aresume, transcripts of all academic work, a description ofresearch and teaching interests, and three letters ofreference to: R. G. Sherman, Department of Zoology,Miami University, Oxford, OH 45056.

Minorities and wonen candidates are strongly encouraged toapply. Miami University is making every effort to create a

diverse, heterogeneousfaculty and staff.

OCEANOGRAPHER/LIMNOLOGIST/AQUATIC ECOLOGISTS

The Department of Biology and the Center for GreatLakes and Aquatic Sciences at the University ofMichiganinvite applications for two positions at the ASSISTANTPROFESSOR rank from individuals broadly skilled inthe aquatic sciences. Outstanding scientists working inany area of aquatic research will be considered, butcandidates must have the ability to conduct research thatintersects disciplinary fields. The candidates' ecologicinterests may span biogeochemistry, microbial ecology,plankton ecology, population enetics, or paleoecologyand focus on community, population, or ecosystem levelsof organization. The interfaces of biology with physics,mathematics, geochemistry, and molecular biology are ofparticular interest to our faculty. Candidates should havedemonstrated an ability to originate funded researchprojects, and will be expected to raise a significantportion of their own salary through research grants. Theopportunity exists for the candidates to interact with adiverse community of aquatic scientists at the universityand at nearby cooperative laboratories. Teaching respon-sibilities will include participation in undergraduatecourses in oceanography, introductory biology, and gen-eral ecology, as well as graduate courses in particularspecialties. Women and minorities are especially encouragedto apply. Applications should include curriculum vitae,representative reprints, and a statement offuture researchplans. Applicants should ask three referees to supplyletters of recommendation. The closing date for applica-tions is 31 January 1991. All materials should be sent to:

Chair, Aquatic Biology Search CommitteeDcpartment of Bioloy

Thc Univcrsity of MichiganAnn Arbor, MI 48109-1048

The University of Michigan is an Equal Opportunity!Affirmative Action Employer.

POSITIONS OPEN

IMMUNOLOGY/MICROBIOLOGYThe Department ofBiology, Umnversity ofSt. Thomas,

invites applications for a full-time, tenure-track positionin immunology/microbiology. The appointment will bemade at the ASSISTANT PROF3SSOR level, effectiveSeptember 1991. Responsibilities will indude teachingupper-division courses for majors in microbiology andimmunology, some laboratory teaching in general (non-majors) and/or introductory (majors) biology, and estab-lishing a vigorous research program involving under-graduate students. St. Thomas is a coeducational,Catholic liberal arts college committed to the total devel-opment of the individual student. The successfil candi-date will have a Ph.D. and a strong commitment toteaching at the undergraduate level and in a liberal-artscontext. Postdoctoral teaching and research experienceare preferred. Send letter of application, brief statementsof teaching philosophy and research plans, and curricu-lum vitae, and have three letters of recommendation sentdirectly, to: Ms. Penny M. Pease, Mail #4050, Uni-versity of St. Thomas, 2115 Summit Avenue, St.Paul, MN 55105-1096. All materials must be receivedby 4 January 1991. The University of St. Thomas is anEqual Opportunity/Affirmative Action Employer.

ORGANIC CHEMIST. Tenure-track faculty posi-tion at the ASSISTANT PROFESSOR level, begin-ning 26 August 1991. Ph.D. in organic chemistry withresearch experience. All specialties will be considered, butexperience in the areas of polymers or synthetic organicchemistry is desirable. Teadcing duties will indude or-ganic lectures and laboratories. The candidate must alsoestablish and maintain a vigorous research program.Collaboration with current faculty in the biomedical areais possible. The involvement of talented senior studentsin faculty-directed research is strongly encouraged. Sub-mit curriculum vitae, three letters of recommendation,and a briefstatement ofresearch interests and plans to: J.K. Cashion, Chairperson, Department of Chenistry,University of Wisconsin-Parkside (UWP), WoodRoad, Box 2000, Kenosha, WI 53141. Applicationsshould be received by 1 Februry 1991. UWP is an EqualOpportunity/AfllrmativeAction Employer. Racial and ethnicminorities, women, and handicappedpersons are encouraged toapply.

VIS1sIING ASSISTANT PROFESSORA position is avilable for up to 5 years (beginning

immediately) to participate or collaborate in the investi-gation of molecular mechanisms of transcriptional regu-lation in yeast and to teach an undergraduate fundamen-tal genetics laboratory course one semester each year.Our research currently focuses on factors that are sus-pected to interact with enhancer-like sequences. Thesuccessful applicant will be interested in pursuing thisproject or a related project of mutual interest, usingmolecular, biochemical, and genetic tools. Applicantsshould send a cover letter with a brief statement ofresearch interests and teaching experience, complete cur-riculum vitae, relevant reprints, and names and addressesof three references to: Genetics Search Committee, c/oDr. Jan Fassler, Department ofBiology, University ofIowa, Iowa City, IA 52242. The University ofIowa is anEqual Opportunity/Affirmative Action Employer. Womenand underrepresented minorities are especially encouraged toapply.

COMPUTATIONAL CHEMIST. The Departmentof Chemistry at Texas A&M University invites applica-tions for a tenure-track faculty position in computationalchemistry at the ASSISTANT PROFESSOR level, tobegin in September 1991. Consideration will also begiven to appointment at the associate professor or pro-fessor levels for more experienced candidates. The ap-pointee will be expected to establish and maintain avigorous research program involving the application oftheoretical and computational methods to problems inorganic and biological chemistry, and to teach at theundergraduate and graduate levels. Applicants must havea Ph.D. degree in chemistry or a related discipline and,preferably, 1 or 2 years of postdoctoral experience.Interested persons should send curriculum vitae and anoutline of research plans and arrange for three letters ofreference to be sent to: Professor Michael B. Hall,Head, Dqeament of Chemistry, Texas A&M Uni-versity, College Station, TX 77843. Applicationsshould be received no later than 15 January 101. TexasA&M University is an Equal Opportuanity/AffirmativeAction Employer.

1290 SCIENCE, VOL. 250

BIOCHEMIST/ENZYMOLOGISTMechanism Based Drug Discovery

The department of Biochemical Parasitology in the MerckSharp & Dohme Research Laboratories has an immediateopening for a Senior Research Biochemist interested in ex-ploring new metabolic pathways as potential chemothera-peutic targets for the treatment and prevention of parasiticdiseases.Primary responsibilities include isolation and characterizationof soluble and membrane associated enzymes and thedesign of screens for the discovery of novel antiparasiticagents. This position offers a unique opportunity to interactwith a team of scientists in various disciplines focused ondeveloping new chemotherapeutic agents.The position requires supervisory experience, a Ph.D. in Bio-chemistry, and at least 4 years of postdoctoral experience ina relevant field of biochemistry. Superior skills in enzymologyand protein purification are essential. The applicant's practicalskills should be complemented by a high level of initiative andsuperior communication skills.

Merck Sharp & Dohrme Research Laboratories is located inRahway, New Jersey approximately 25 miles from New YorkCity. Our facilities are state-of-the-art and our renownedresearch environment is excellent. For consideration, pleasesend your resume with the names of three references toHuman Resources Manager, Merck & Co., P.O. Box 2000,WBC-1 55, Dept. S-12, Rahway, NJ 07065.

An equal opportunity/affirmative action employer m/f/v/h

PENNUNI VERSITr of PE.Y:NS rL VANIA

Eldridge Reeves JohnsonProfessorship

The University of Pennsylvania School of Medicineinvites nominations and applications of outstandingscientists to fill a newly created professorship namedand supported by the Eldridge Reeves Johnson Foun-dation. The Foundation, established in 1929, has a dis-tinguished record of contributions to medical physicsand biophysical technology. The successful candidatewill be active in the area of Biomolecular Structureand Function. In addition to a faculty appointment inthe Department of Biochemistry and Biophysics, theindividual will have the opportunity to participate indeveloping a group of outstanding scientists and stu-dents in the area of molecular biophysics.The University is an equal opportunity affirmative

action employer. Women and minority candidates areencouraged to apply.

Please submit nominations or self-applications to:

Franz M. Matschinsky, M.D.Chairman, Johnson ProfesorshipSearch Committee

University of PennsylvaniaSchool of Medicine

414 Anatomy-Chemistry Building3600 Hamilton WalkPhiladelphia, PA 19104-6059

-.

Wayne State University

FACULTY POSITIONSThe Department of Biological Sciences is undertaking a major

development effort, including the occupation of a new BiologicalSciences Building in Spring, 1991 and the recruitment of a significantnumber of new faculty over the next 4 years. The establishment ofseveral new teaching and research initiatives for graduate and under-graduate students includes a graduate Molecular Biotechnology Pro-gram and a Howard Hughes Undergraduate Education Initiative in celland molecular biology. We invite applications for three tenure-trackfaculty positions at the Assistant or Associate Professor level, tobegin in August, 1991, in the following broad areas:

MICROBIOLOGY/MOLECULAR GENETICSMOLECULAR CELL BIOLOGY

NEUROBIOLOGYApplicants should have a doctoral degree and suitable postdoctoral

experience. Successful candidates will be expected to teach at theundergraduate and graduate levels and to establish extramurally-funded research programs. WOMEN AND MINORITY CANDIDATESARE ENCOURAGED TO APPLY. Review of candidates will beginJanuary 15, 1991 and continue until suitable candidates have beenidentified. Send curriculum vitae, including a one-page statement ofresearch interests, and the names of at least three references to:

Dr. P. Dennis Smith, ChairmanFaculty Search Committees

Department of Biological SciencesWayne State UniversityDetroit, Michigan 48202

Wayne State University is an Equal Opportunity/Affirinative Action Employer

-.U----

I IfiThe University of SydneyAUSTRALIA

LECTURESHIP(FIXED TERM)School of Physics

Reference No. 44/04The Chatterton Astronomy Department within the School of Physics isin the process of commissioning the new Sydney University StellarInterferometer (SUSI). SUSI is an optical interferometer ofunprecendented angular resolving power with baselines covering the

range 5-640 m and a limiting sensitivity of approximately 8th magnitude.It is capable of undertaking a wide range of programs in stellarastrophysics. An expenmental physicist/astrophysicist is required toparticipate in the stellar interferometer program.The appointee will be required to participate in the general teachingprogramme of the School of Physics at the undergraduate andpostgraduate levels, to participate in the operation and development ofthe stellar interferometer, and to carry out research in stellarastrophysics.Further information from Professor J. Davis, School of Physics612 692 3604.This appointment will be for a fixed term from January 1991 to 31December, 1993.Salary range: $A33,163-$A43,096 p.a.

Closing: 25 January, 1991.

Mthod AppIkatIon: Applications, quoting Reference No., andincluding curriculum vitae, list of publications and the names, addressesand fax. nos., of three referees (only three referees will be contacted inthe first instance and if more referees are nominated they should beranked in order of preference) to the Registrar, Staff Office, Universityof Sydney, NSW 2006, Australia, by the above closing date.

Equal employmentopportunity andno smoking in the workplace areUniversitypolicy.I

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i

;

60

Du Pont Merck Pharmaceuticalshas 2 challen g openings in the Molecu-lar Biology Department in its ReceptorBiology Group.

Molecular Biology ScientistCandidate must have expenence in a fullrange of recombinant DNA techniques toperform research on the cloning, expres-sion and structure-function relationshipsof cellular receptors. The successful can-didate should also possess anMS degreein Molecular Biology, Biology or Bio-chemistry with three or more years oflaboratory experience and a demonstratedability to conduct independent research.Experience with protem electrophoresis,immunochemical techniques and tissueculture is helpful. Exceptionally qualifiedcandidates with BS degrees will also beconsidered.

Postdoctoral Visiting ScientistCandidate will focus on purification, clon-ing, structure-function relationships andsignal transduction mechanisms of cellu-lar receptors. Applicants should have aPhD in Biochemistry, Immunology orMolecular Biology and publications deal-ing with receptor lsolation, cloning and/orfunctional analysis. The appointment isfor a period of one year, renewable for asecond year upon mutual agreement.

Consider an innovative company thathas strong concern for both its employeesand our environment. Consider Du Pont.

You'll find a stimulating environment atour Wlmington, Delaware location whichoffers a wice range of academic, culturaland recreational activities. Qualified can-didates for both positions should send acurriculum vitae and three letters ofrecommendation, indicating position ofinterest to: Du Pont Human Resources,Room 1'SS-0031, Wilmington, DE 19898.

An Equal Opportunity

~~~~Em ployer

C82~--VeterinauryPathologist

Takeacto#

drewlqmeiif

Asa $3+ billion health care leader, we createpharmaceuticals that enhance, improveand prolong life for both humans andanimals. Our dedication to discovery hasled to innovations that have won Schering-Plough top recognition around the world.As part of Schering-Plough's Safety Evalua-tion Center, you will have the responsibilityfor the drug safety program supporting allSchering-Plough Animal Health productregistrations. This will entail ensuring thetimely planning, execution, reporting andinterpretation of appropriate animal andenvironmental toxicology studies and in-tegration of study results with informationfrom other functions, such as drug metabo-lism and pharmacokinetics.Successful candidate will possess a DVMand Ph.D., along with ACVP-board certifi-cation and at least 3 years of relevant ex-perience in toxicologic pathology. Desir-able work experience includes investiga-tions involving livestock and/or companionanimal species, interaction with govern-mental regulatory authorities, especiallythe FDA Center for Veterinary Medicine,and project management responsibilities(sponsor's representative) for studies con-ducted at contract laboratories.We will reward your achievements with anexcellent salary and outstanding benefitspackage. For immediate consideration,please forward your resume with salary re-quirementsto: Mr. R. Blackburn,Schering-Plough Research, 60 OrangeStreet, Bloomfield, NJ 07003. We are anequal opportunity employer.WbaetyYo/h.veilnirnd, wepffirtoactiom

C/36Schering-Plough

-

I

M.

DOCTORAL PROGRAMIN

PHYSIOLOGYAND

NEUROBIOLOGY

Prospective Graduate Students and Post-doctoral Trainees are invited to applyto the Program in Physiology andNeurobiology jointly administered byRutgers University and The University ofMedicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.Scientists are located at the RobertWood Johnson Medical School, RutgersUniversity, and the new Center forAdvanced Biotechnology and Medicine.Facilities are located on the scientificBusch Campus in the New Brunswick/Piscataway area. Representativeresearch areas include molecular neuro-biology, developmental neurobiology, cel-lular neurobiology, systems biology, andthe relationship of biology to behaviorand mentation. Tuition remissions andstipend support will be offered to out-standing candidates for the graduate stu-dent positions.

For information and application formscontact:

Dr. Ira B. Black, ChairmanDepartment of Neuroscienceand Cell BiologyUMDNJ-Robert Wood JohnsonMedical School676 Hoes LanePiscataway, NJ 08854-5635(201) 463-5388

RU and UMDNJ are Affirmative Action/EqualEmployment Opportunity Employers, M/F/HN,and UMDNJ is a member of the Univer-sity Health System of New Jersey.

- E W I E RSE Y

THE INTERNATIONAL RICE RESEARCH INSTITUTE (IRRI)seeks three (3) Agricultural Scientists

for assignment to Egypt

The successful candidates (one of whom will be theteam leader) will work in collaboration with Egyptiannational scientists and officers of the Rice Research andTraining Center. All must have demonstrated ability towork as members of interdisciplinary teams and must befluent in English.Agronomist (Weed Science)Duties: Collaborate with Egyptian rice scientists in thedesign, implementation and analysis of on-station andon-farm research leading to the development of im-proved weed management techniques, particularly fordirect-seeded rice. Determine the distribution and impor-tance of weeds in different rice environments. Study theeffect of shifting from transplanting to direct seeding onweed species composition. Develop economically-viablemanagement practices for improved weed control inrice. Provide on-the-job training to Egyptian rice scien-tists in weed science research.Qualifications: Ph.D. in agronomy or related field and atleast 5 years experience in weed science research.Agronomist (Soil Fertility Improvement)Duties: Collaborate with Egyptian rice scientists in thedesign, implementation, and analysis of on-station andon-farm research leading to development of practices forsoil fertility improvement in rice-based farming systemswith emphasis on direct-seeded rice. Identify and re-solve soil fertility constraints to rice yields on saline/alkaline soils. Develop and evaluate fertilizer practices inassociation with improved water use efficiency. Provideon-the-job training to Egyptian rice scientists in agro-nomic research to improve soil fertility.Qualifications: Ph.D. in soil science or related field andat least 5 years experience in soil fertility research.Plant BreederDuties: Collaborate with Egyptian rice scientists in ricevarietal improvement research. To generate, evaluate,and select improved rice varieties with high yield poten-tial, resistance to insect pests and diseases, and toler-ance for soil salinity/alkalinity. Provide on-the-job train-ing to Egyptian rice breeders in the approaches andtechniques of rice varietal improvement.Qualifications: Ph.D. in plant breeding or related fieldand at least 5 years experience in varietal improvement.IRRI is an international, non-profit, donor-funded agricul-tural research institute that undertakes research andtraining at its headquarters in the Philippines and collab-orates with national agricultural systems worldwide.IRRI's goal is to develop more productive and sustain-able rice technology and to strengthen national researchcapability. Salary and benefits will be commensuratewith those of similar international institutions and pro-grams in agriculture.Application: Applications for the positions described willbe accepted until 31 December 1990. Please submitcurriculum vitae, date of availability, and the names ofthree referees to:

Dr. Klaus Lampe, Director GeneralIRRI, PO Box 933, 1099 Manila, Philippines

FAX: 63-2-817-8470. TELEX: 40890 RICE PM or22456 IRI PH

_. i

NPOSITIONS OPEN

ASSISTANT PROFESSOR IN BEHAVIORALNEUROSCIENCE. The Ncuroscience Program andthe Psychology Dcpartmcnt at Princeton University hasa position opcn for the fall of 1991. The positioninvolves tcaching and research and is open to any area ofneuroscience with an emphasis on behavior or function.Send curriculum vitae, a one-page research desption,and three letters of recommcndation to: Chair, N'euro-science Search Committee, Code NB, Department ofPsychology, Princeton University, Princeton, NJ08544-1 10. Applications preferred by 15 February1991. Princeton University is an Equal Opportunity/Affir-mative Action Employer.

VERTEBRATE ANATOMY/PHYSIOLOGYASSISTANT PROFESSOR. Tenure-track position

(pending funding). Doctorate required; teaching andpostdoctoral experience preferred. Primary teaching du-ties will bc human anatomy and physiology as well ascourses in candidate's specialty. Candidatc iS expected tocstablish a research program and to participate in thegraduate program. Candidates will be evaluated on theirability to complement the existing faculty specialties;neurobiologists, functional morphologists, or mammal-ogists are encoud to apply. Submit resume, tran-scnpts, statement of teaching philosophy, research plans,and threc references by 1 January 1991 to: Dr. BonnieSamsell, Chairman, Biology Department, State Uni-q College at Buffalo, 1300 ElImwood Avenue,Bulo,NY 14222. Buffalo State College is an Equal

Opportunity/Affrmantive Action Employer.

CALIFORNIA INSTITUE OF TECHNOLOGYThe Computation and Neural Systems (CNS) pro-

gram at Caltech is conducting a search for a tenure-trackASSISTANT PROFESSOR on the engineering side ofCNS, for which the term of initial appointment isnormally four years. CNS is an interdisciplinary Ph.D.program established in 1986 that brings together engi-neers and scientists who are applying ideas from neuro-biology to the development ofnew computational devic-es and systems and biologists who are investigating howcomputation is done in the nervous system. Areas ofinterest indude motor control, learning, speech, visionand artificial neural networks. The appomtee will beexpected to develop a strong research activity and toteach courses in his or her specialty. Applicants shouldsend a resume, induding list of publications; a briefstatement of research accomplishments and goals; andthe names of at least three references to: Professor Y.Abu-Mostafa, Caltech 116-81, Pasadena, CA 91125.Caltech is an Equal Opportunity Employer and it specificallyencourages women and minorities to apply.

ASSISTANT/ASSOCIATE PROFESSOROF ASTRONOMY

The Interdisciplnary General Arts and Sciences Pro-gram at Arizona State University West invites applica-tions for an assistant/associate professor of astronomy. APh.D. in astronomy, an excellent research record, andsuccessful teaching experience at the university level is

required. Appointment as associate with teaching, pub-lications, and record of continuing professional andscholarly achievement. Administrativc exprince at thedepartmental level or above and successful funding his-tory for research or curriculum development wouldbe anasset.

This individual will teach upper-division courses inastronomy and develop with other faculty a new inter-disciplinary program in arts and sciences. The person willbe exetdto develop and partiapate in team-teaching asenmnar which integrates ideas from the humanities andthe sciences. Because this ncw degree program is aimed atreurning adult learners, prior expenence working withthis population would be an additional asset.

Letter of application addressing teaching philosophy,scholarly development and area of research, and curricu-lum development ecperience; curriculum vitae; andnames and addresses of three references are due by 15December 1990. Send materials to:

Thomas V. McGovernDirector of Arts and SciencesArizona State University West4701 West Thunderbird RoadPhoenix, AZ 85069-7100

ASU West is an Equal Opportunity/Affirmative ActionEmployer.

1294

ASSISTANT PROFESSOR, BIOCHEMISTRY.The Department of Biochemistry at the University ofVermont seeks to fill a full-time (12-month appoint-ment), tenure-track faculty position at the level ofassist-ant professor. Applicants with a commitrnent to gradu-ate/medical student education, collaborativc researchinteractions with university faculty, and a vigorous inde-pendent research program are encouraged to apply.Individuals with postdoctoral research expenence and aninterest in one ofthe following three subject areas will begiven special consideration: (i) cellular receptors; (ii)gene re%ulation/development, emphasis on DNA:proteininteractions; or (iii) mammalian viroloVy. The depart-ment, located within the College ofMedicine, has stronginteractions with allied departrnents and is an activeparticipant in institutional teaching and rcsearch pro-grams in the areas of cancer biology, cell and molecularbiology, thrombosis and hemostasis, pulmonary biology,and biotechnology. The 425-acre main campus of theUniversity ofVermont is located beside Lake Champlain,between the New York Adirondack and Vermont GreenMountains, and resides within a community of about80,000 people. Interested individuals should send ar6sumr, a description of career goals and research inter-ests, and names of three references to: Dr. George L.Long, Department of Biochemistr, College of Med-icine,Uivty ofVermont, Burlgn, VT 05405.Women and people fitm diverse racial, thnic, and culturalbackgrounds are encouraged to apply. Applications will beaccepted until 1 March 1991. The Univenity of Vermontis an Affirmative Action/Equal Opportunity Employer.

UNIVERSITY OF MICHIGANPALEOBOTANIST

The Department of Biology and Museum of Paleon-tology invite applications for a joint tenure-track positionin paleobotany. We seek applicants with broad researchand teaching interests in paleobiology and expertise inthe systematics of fossil plants. Ph.D. is required. Weanticipate appointment will be made in 1991 at theASSISTANT PROFESSOR level. Successful candidatewill be expected to participate in undergraduate teachingprograms of the Department of Biology, train graduatestudents, and develop a vigorous extramurally supportedresearch program in the museum. This appointmentinvolves curatorial responsibility for a major paleobotan-ical research collection. Current faculty in paleontologyare D. C. Fisher, M. Foote, P. D. Gingerich, and G. R.Smith. University resources indude strong programs inorganismic and evolutionary biology and in sedimentarygeology. Send resume, brief statement of research inter-est, and names offive people we can contact for letters ofrecommendation to: Professor Philip D. Gingerich,Search Committee Chair, Museum of Paleontology,The University of Michigan, Ann Arbor, MI 48109-1079. Closing date for applications is 31 January 1991.The University ofMichigan is a nondiscriminatory, Affirna-tive Action Employer.

INSTRUCTOR OR ASSISTANT PROFESSORRADIATION ONCOLOGY

Facilities located in a new cancer hospital, occupying30,000 square feet, indudes three linacs, plus dedicatedintraoperative linac, hyperthermia, HD remote afterload-ing, dedicated CI scanner, two simulators, conventionaland two 3-D treatment planning workstations. Require-ments: Board-eligible with demonstrated interest in aca-demic medicine. Send resume to: Dr. Reinhard A.Gahbauer, Radiation Oncology, Arthur James Can-cer Hospital and Research Institute, The Ohio StateUniversiy, 300 West 10th Avenue, Columbus, OH43210.

CLINICAL MICROBIOLOGIST. LaboratoryMedicine Departnent, Yale University, recruiting an

ASSISTANTOR ASSOCIATE PROFESSOR in mi-

crobiology at Yale New Haven Hospital. Succcssfulcandidate must establish indepcndent research program,participate in managing laboratory, teach residents/med-ical students. Prefer applicants to be Board-certified orBoard-eligible in clinical pathology and/or medical mi-crobiology with M.D. and/or PE.D. Send curriculumvitae and three references to: Stephen Edberg, Ph.D.,Chairman, Search Committee, Yale UniversitySchool of Medicine, 333 Cedar Street, New Haven,CT 06510 before 15 January 1991. Yale is an EqualOpportunity/Affirmative Action Employer. Women and mi-nority applicants encouraged.

ASSISTANT/ASSOCIATE PROFESSOR. Biolo-tenure-track position. Available September 1991. The

oined Biology Department of Manhattan College/Col-lege ofMount Saint Vincent seeks a geneticist/molecularbiologist for teaching introductory genetics courses and agraduate level course in molecular biology. Ph.D. re-quired. Send curriculum vitae, statement of teachingphilosophy, and three letters of recommendation by tJanuary 1991 to: Dr. William A. Tramontano, Chair,Department of Biology, Manhattan College/CollegeofMount Saint Vimcent, Riverdale, NY 10471. Wom-en and minorities encouraged to apply. An Affirmative Ac-tion/Equal Opportunity Employer.

Arizona State University (ASU) West, a growingupper adicasio and gduate campus in the ASU system,seesppicaios orpositions at the ASSISTANIT

AND/<5tASSOCIATS LEVELS in ecology and evo-lutionary biology. Ph.D. required for associate professoralong with teaching and pub1hcation requirements at theassociate level. Teaching responsibilities will indude in-struction ofundergraduate majors, nonmajors, and grad-uates. A special interest in interdisciplinary undergradu-ate instruction is desired. Scholarly interests and researchshould address issues related to, or that connect naturallywith, south western systems. Teaching, salary, and start-up packages are competitive with other state researchuniversities. Though not required, some postdoctoraland/or advanced experience is desired for assistant-levelappointments. To facilitate both research and teaching, aCenter for South Western Ecology is being planned.* Vertebrate Physiological Ecology, with a focus

on, or interests that connect naturally with, south west-em systems. Research should have an evolutionary em-phasis and a strongly quantitative approach.* Ecological Genetics, with a focus on, and/or em-

pirical and theoretical interests that connect naturallywith, south western systems. Research should have anevolutionary emphasis, utilize current methodologies,and have a strongly quantitative approach.By4 January 1991, please send (i) letter ofapplication,

that addresses experience, interests, and goals, and thatspeifies the exact title of the position sought, (ii) curric-ulum vitae, (iii) no more than five representative publi-cations, and (iv) three letters of recommendation to:

CoordinatorLife Sciences Program

Arizona State University WestP.O. Box 37100

Phoenix, AZ 85069-7100Telephone: 602-543-6000

ASU West is an Equal Opportunity and AffirmativeAction Employer.

INFECTIOUS DISEASESFACULTY POSMONS

The University of California, Los Angeles (UCLA),Division of Infectious Diseases, Department of Medi-cine, at the UCLA Center for the Health Sciences inWestwood is recruig two tenure-track faculty mem-bers at the ASSISTANTOR ASSOCIATE PROFES-SOR leve. The positions indude independent laboratoryspace and equipment, start-up funds, and protected time.Applicants must be Board-certified in internal medicineand Board-eligible or -certified in infectious diseases.Applicants must be prepared to establish an independentresearch program in one of the following areas: (i)intracellular parasitism, host-bacterium interaction, orhost-parasite interaction; or (ii) retrovirology or basicAIDS research. Applicants must have a minimum of 3years of full-time experience in basic laboratory investi-gation, acquired state-of-the-art skills in cell biology,immunology, biochemistry, or molecular biology, andpublished at least one first-authored paper in a presti-gious peer-reviewed laboratory research-oriented jour-nal. Send curriculum vitae; three copies of all papers,abstracts, manuscripts in press, and manuscripts submit-ted (optional); statement offuture research interests; andthree letters of recommendation to: Infctious DiseasesSearch Committee I (Intracelluar Parasitism etc.) orfl (Retrovirology/AIDS), c/o Marcus A. Horwitz,M.D., Chief, Division of Infectious Diseases, Depart-ment ofMedicine, UCLA School ofMedicine, Centerfor the Health Sciences, 37-121, Los Angeles, CA90024-1688. All materials should be sent by 31 De-cember 1990 or as soon as possible thereafter. Th7eUCLA School ofMedicine is an Equal Opportunity/Affir-mative Action Employer.

SCIENCE, VOL. 250

POSITIONS OPEN POSITIONS OPEN

Bioprocess DevelopmentOpportunities At Te Forefront

Medical Research

The Medical Research Division ofAmerican Cyanamid Company is recog-nized intemationally as a leader in theresearch and development of therapeuticcompounds. Our products have been in-strumental in the treatment of infectiousdiseases, cancer, cardiovascular andcentral nervous system diseases. To buildupon our strengtis and create an environ-ment that will foster an even stronger andmore dynamic R&D or anization, we seekoutstanding scientis or our FermentationDevelopment Department.Group Leader-MicrcbiologyThe technical responsibilities of this posi-tion relate to the conception, developmentand improvement of microbially-basedprocesses for the producton of a variety ofhuman and animal health products such asantibiotics, recombinant DNA-derived pro-teins, enzymes and other compounds withunique biological or chemical activities.The individual we are seeking will have di-rect supervisory responsibility for a groupof 10-12 scientists and technicians work-ing in several project areas including mi-crobial physiology and biochemistry,genetics, molecular biology and biotrans-formation. The successfulcandidate mustbe able to work effectively within a multi-disciplinary project team environment withprotein, organic, and analytical chemistsand process engineers.To qualify for this highly visible position,

a Ph.D. in Microbiology, or aclosely related fiel is

_o frequired as is several years_ opostdoctoral expenence,preferably within industry.

Previous supervisory responsibility isnecessary. (Dept. DS)

Protein BiochemistsThe Biochemistry Group has two openingsfor Ph.D. scientists experienced in proteinisolation and characterization. These indi-viduals will have responsibility for the iso-lation and purification of recombinant andnaturally-produced proteins from biologi-cal processes and will provide technicalsupport to the Biochemical EngineeringDepartnent for large-scale downstreamprocessing. The development and imple-mentation of analytical assays for proteincharacterization are also required. A min-imum of two years postdoctoral training isnecessary. Additional industrial and large-scale processing experience is desirable.(Dept. VD)Bioanalytical ChemistThe Analycal Development Group has anopening for a Ph.D. scientist to establishprocedures and methods for the characteri-zation and quantification of antibiotics,proteins and other bioactive molecules.The application of bioanalytical technolo-gies to improve and optiize biologicalprocesses will also be required. A back-ground in microbiology and biochemistryIs desirable. Postdoctoral experience ispreferred. (Dept. FB)All positions offer competitive salares andexcellent benefits and are located at theLederle Laboratories Campus of AmericanCyanamid in Rockland County, justtwenty-five miles north of New York City.For immediate consideration, please sendyour resume/c.v. with salary requirementsindicating the departnent code for theposition of your choice to: ProfessionalEmployment Representative, Lederlelaboratories, 401 N. Middletown Road,Pearl River, New York 10965. An EqualOpportunity Employer m/f.

Dedicated People Dedicated To People Since 1906.

-1

POSITIONS OPEN

ASSISTANT/ASSOCIATE PROFESSORINFECTIOUS DISEASES

The ID Section at Hospital of the University ofPennsylvania has openings for assistant and associateprofessors who are Board-certified/Board-eligible in ID.Applicants must have excellent capabilities in basic sci-ence research. Qualified individuals with interests in allID-related areas of investigation are invited to apply.Particular emphasis in recruiting will be placed on indi-

viduals expenenced in herpesviruses, retrovirology, andbacterial pathogenesis. Clinical responsibilities includeconducting attending rounds in ID and Internal Medi-cine for a total of 2 to 3 months yearly. Send curriculumvitae to: Harvey Friedman, M.D., Chief InfectiousDiseases, 536 Johnson Pavilion, University of Penn-sylvania, Philadelphia, PA 19104-6073. Equal Oppor-tunity/Afirmnative Action Employer.

BIOLOGY. Two tenure-track positions to begin 1September 1991. (i) ASSISTANT OR ASSOCIATEPROFESSOR Vertebrate or invertebrate physiology orrelated area. (ii) ASSISTANT PROFESSOR. Mo ecu-lar or cellular biology. Ph.D. required. Teach upperdivision courses in specialty as well as introductorycourses. Teaching in interdisciplinary programs, collab-oration with medical and engineering faculties, researchinvolving undergraduates are all possibilities. Send cur-riculum vitae, a statement of teaching and researchinterests, and three letters of recommendation to: JohnD. Shepherd, Biology Department, Coliege ofLiberalArts, Mercer University, Macon, GA 31207. We areespecially interested in women and minority candidates. Af-firmative Action/Equal Opportunity Employer. Applicationdeadline: 4 January 1991.

NEUROBIOLOGY/CELL BIOLOGY

Applications are invited for two tenure-track or ten-ured positions at ASSISTANT TO FULL PROFES-SOR levels. Available 1 Scptember 1991. Candidatesshould have a Ph.D., M.D., or equivalent degrec, andhave demonstrated ability to conduct independent re-search and attract extramural funding. All areas of spe-cialization are encouraged to apply, although specialconsideration will be given to those mterested in cellulardevelopmental biology, membrane structure and func-tion, neural plasticity, and regeneration. The candidateswill be cxpected to participate in team teaching of tissuebiology or neuroanatomy to medical students. Appli-cants should submit curriculum vitae, a brief statement ofrescarch interests, representative reprints, and names ofthree references by 31 January 1991 to: Dr. George D.Pappas, Search Committee, Department of Anatomyand Cell Biology, University of Illinois, College ofMedicine at Cicago, P.O. Box 6998 (M/C 512),Chicago, IL 60680.The University of Illinois is an Equal Opportunity!

Affinmative Action Employer and encourages applicationsfrom women and minorities.

UNIVERSITY OF VICTORIAMYCOLOGY/PLANT PATHOLOGY

The Department of Biology, University of Victoria, isseeking as a tenure-track ASSISTANT/ASSOCIATEPROPESSOR, a person with expertise in mycologyand/or plant pathology, with preference given to a can-didate carrying out research in the area of molecular/cellular biology of fungi. The successful applicant will beexpected to teach mycology in our lower-level corebotany course and to provide more specialized instruc-tion related to the candidate's area of expertise in ourupper-level program. The deadline for applications is 31January 1991. Applicants must send their curriculumvitae, at least one copy each oftwo recent publications, adescription of research interests, and names of at leastthree referees who can be contacted to:

Dr. Louis A. Hobson, ChairDepartment of BiolosyUniversity of Victoria

P.O. Box 3045Victoria, BC, Canada V8W 2Y2

In accordance with Canadian Immigration requirements,priority will be given to Canadian citizens and permanentresidents. The University of Victoria is committed to an

employment equity program. Women are particularly encour-

aged to apply.

1296

POSITIONS OPEN

ASSISTANT/ASSOCIATE PROFESSORIMMUNOLOGIST

The Department of Pathology, Brigham and Women'sHospital and Harvard Medical School, invites applica-tions for a faculty position at the rank of assistant orassociate professor. Outstanding applicants with exper-tise in molecular immunology, transcnptional regulation,and lymphocyte differentiation and activation are encour-aged to apply. Applicants should have a Ph.D. and/orM.D. degree and have completed postdoctoral training.Send curriculum vitae, list of publications, description ofresearch interests, and names of three referees to: Dr. AK Abbas, Dcpartment of Pathology, Brigham andWomen's Hospital, 75 Francis Street, Boston, MA02115. The hospital is an Equal Opportunity Employer.

CHAIRPERSON, PHYSIOLOGY. The MedicalCollege of Pennsylvania invites applications and nomina-tions for the position of Chairperson, Departrnent ofPhysiology.The department has recently been formed and has been

targeted for significant expansion in personnel and space.This is an excellent opportunity for a leading scientist todevelop a nationally recognized research and trainingprogram. The medic college seeks a distinguished edu-cator with an established record of scientific productivityand ability to secure external funding, along with excel-lence as a teacher and leader. Cell or membrane physiol-ogy and molecular biology are areas ofparticular interest.A letter of interest or nomination, curriculum vitae, andthe names of at least three references should be sent to:Alan S. Bellack, Ph.D., Chair, Physiology SearchCommittee, Department of Psychiatry, The MedicalColee of Pennslvania, 3200 Henry Avenue, Phila-delphia, PA 19129. Equal Opportunity/Affirmative Ac-tion Employer.

CHAIRDEPARTMENT OF MICROBIOLOGY

AND IMMUNOLOGY

Morehouse School of Medicine (MSM) invites appli-cations and nominations for the position ofprofessor andchair, Department of Microbiology and Immunology,which will become vacant in 1991 due to the impendingretirement of the current chair. The department hasrecent funding indcuding that for AIDS research and ispart of a rapidly expanding, 4-year medical school dedi-cated to the training of minority physicians. Applicantsare expected to have a record of significant researchachievement, extramural funding, and substantial admin-istrative/teaching skills. Experience in immunology ispreferred. Applications/nominations should be submit-ted by 15 February 1991 to: Catherine S. Chew, Ph.D.,Chair, Microbiology/Immunology Search Commit-tee, Morehouse School of Medicine, 720 WestviewDrive, S.W., Atlanta, GA 30310-1495.MSM is an Equal Opportunity/Affirmative Action Em-

ployer.

POSITIONS OPEN

ENVIRONMENTAL HEALTH SCIENTIST/DEPARTMENT CHAIR, Department of Environ-mental Health, East Tennessee State University, academ-ic year, tenure-track, associate/full professor. Rank andsalary commensurate with qualifications and experience;fall 1991. Minimum qualfcations include a Ph.D. inenvironmental health science or closely related field withadministrative experience in higher education and eligi-bility for certification by a related professional board.Willingness to teach undergraduate and graduate stu-dents as necessary. Must be capable of integrating talentsof both environmental and public health scientists. Evi-dence ofstrong established scholarly research activity anda record of outstanding extramural grant support re-qurcd. Must lead and coordinate a department of seven

faculty, 160 undergraduates, and 60 graduate students,in a variety of areas of concentration.Send current curriculum vitae; names, addresses, and

telephone numbers of five references; and documenta-tion of current grant funding and research to: Dr. GuyR. Lanza, Dean, School of Public and Allied Health,East Tennessee State University, Box 21190-A,Johnson City, TN 37614. The deadline for receivingcompleted applications is 15 March 1991. An EqualOpportunity/Affirmative Action Employer.

MANAGER OFBIOLOGICAL DATABASE SYSTEMS

The Arnold Arboretum, the Harvard University Her-baria, and the Museum of Comparative Zoology ofHarvard University seek an individual who will workwith the scientific staffs of these institutions to developand manage databases and networking activities relatedto their collections. She/he will be responsible for long-range planning for and acquisition of hardware andsoftware, as well as for network connectivity for thebiological specimen data resources in organismic biolo-gy.The individual will develop proposals for externalfunding for development of database systems. As muchas one third time could be devoted to externally fundedresearch in systematics or information technology.Strong preference for a Ph.D. in biological systematics orrelated fields and experience with biological accessiondata. Experience with university computing operations,UNIX systems, and TCP/IP-based network communica-tions is essential. Send letter of interest, resume, andthree letters of reference to: Dr. Robert E. Cook,Director, Arnold Arboretum, 125 Arborway, Jamai-ca Plain, MA 021130.

CURATORSHIPARTHROPOD SYSTEMATICS

AMERICAN MUSEUMOF NATURAL HISTORY

The American Museum of Natural History invitesapplications for a tenure-track curatorial position in itsDepartment of Entomology. The primary responsibilityof the position is high productivity in original researchon the systematics of insects, arachnids, or myriapods.The area of research specialization is otherwise unrestrict-ed; salary and rank will be commensurate with experi-ence.Other responsibilities of the position include, but are

not limited to, (i) curation of part of the department'scollections of 16.7 million specimens, (ii) participation inthe department's joint graduate student training pro-grams with Comell University and the City ofUniversityof New York, (iii) participation in museum committeesand exhibition programs, (iv) supervision of departmen-tal support staff, and (v) future service, on a rotatingbasis, as departmental chairperson. The position will beavailable beginning July 1991. A Ph.D. (or equivalent)and demonstrated success in, or potential for, attractingexternal research funding are required.

Applicants should forward (i) a statement of researchinterests and goals, (ii) curriculum vitae with completebibliography and reprints, and (iii) names, addresses, andtelephone numbers of at least three evolutionary biolo-gists familiar with the applicant's qualifications and ac-complishments. Applications must be submitted by 31January 1991 to:

Dr. Norman I. Platnick, ChairmanDepartment of Entomology

American Museum of Natural HistoryCentral Park West at 79th Street

New York, NY 10024An Equal Opportunity Employer.

SCIENCE, VOL. 250

ENDOWED CHAIRIN HUMAN NUTRMTION

Applications are being accepted for the LillianFountain Smith Chair in Human Nutrition inthe Department of Food Science and HumanNutrition at Colorado State University (CSU).The individual should be a senior person withestablished credentials appropriate or appoint-ment as a fill professor. It is expected that thechair will develop strong research and teachingprograms related to human nutrition and havedemonstrated ability to obtain outside funding.Ph.D. or M.D. degree is required. Appointmentwith tenure will be on an academic year basiswith the expectation that the person will seeksummer funding.

Application deadline is 15 January 1991 withanticipated starting date of 20 August 1991.CSU is an Equal Opportunity Employer. Applica-tion letters including curriculum vitae and namesof four references should be submitted to: En-dowed Chair Search Committee, Departmentof Food Science and Human Nutrition, Col-orado State University, Fort Collins, CO80523.

I 11~~~~~~~~~~~~~~~~~. I

DIRECTORWESTERN HEMISPHERE COOPERATION PROJECT

Nation's leading general science and engineering association, basedin Washington, DC., seeks a Director for its Western HemisphereCooperation Project (WHC). Director will manage cooperative pro-grams with counterpart organizations in the Western Hemisphere;organize symposia on scientific topics of relevance to the region;monitor special issues in Latin American science; and raise funds tosupport WHC activities. Director will also serve as official liaison toInterciencia Association, a federation of 14 national scientific organiza-tions in the Americas.

Minimum qualifications include: Master's degree in a field ofscience or in Latin American studies; 3-5 years' experience inmanaging international cooperative programs, or a combination ofeducation and related work experience; excellent communicationskills; experience in working with grant-making organizations; and "in-country" experience in one or more countries of the WesternHemisphere. Candidate must be fluent in English and be able tocommunicate effectively in Spanish. A knowledge of Portuguese isdesirable. Please send letter expressing interest together with currentresume and salary requirement to:

Debra WrightOffice of Human Resources, Suite 854

American Association for the Advancement of Science1333 H Street, NW, Washington, DC 20005

Closing Date December 31, 1990

AAAS is an Equal Opportunity Employer.

IFaculty PositionIn

ANIMAL MOLECULAR VIROLOGYPurdue University

Department of Biological Sciences

We invite applications for a tenure-track posi-tion at the Assistant or Associate Professorlevel. The Department is particularly interested incandidates with research interests in, but notlimited to, virus assembly, virus-host interac-tions, virus neutralization by antibodies andanti-viral agents directed against the virion.Candidates must have a Ph.D. degree or equiva-lent, postdoctoral experience and demonstrateexceptional promise in research. The successfulapplicant is expected to develop a vigorous,extramurally-funded research program, to partic-ipate in teaching a course in a relevant discipline,and to participate in graduate training. The ap-pointment offers an excellent opportunity to joinan expanding program in molecular virology andto join eleven other faculty members in theMarkey Center for Structural Biology.

Applications, including a curriculum vitae,names and addresses of at least three references,a statement of current research activities and adescription of future plans should be sent to:

Professor John E. Johnson, ChairMarkey Faculty Search CommitteeDepartment of Biological Sciences

Purdue UniversityWest Lafayette, Indiana 47907 U.S.A.

Applications will be accepted until January 1,1991, or until a suitable candidate is identified.Equal Opportunity/Affirmative Action Employer.

PresidentScience Service Incorporated

Washington, DCScience Service, Inc., invites nominations and

applications for the position of President. Found-ed in 1921, Science Service is a not-for-profitorganization devoted to increasing public under-standing of science, informing society's leadersof new developments in science and encourag-ing precollege students to become involved inscientific research. Among its many activities,Science Service publishes Science News andadministers the Westinghouse Science TalentSearch.

Candidates must have demonstrated an un-derstanding of and commitment to science, aswell as outstanding management skills. Publish-ing experience in science also is desirable, as isthe capacity to develop proposals and obtainfunding for new projects and activities from bothgovernment and industry sources. In particular,the trustees are interested in broadening andstrengthening Science Service's programs foryouth and in exploring opportunities to make useof new media.

Applications and nominations are requestedby January 15, 1991. Inquiries, nominations orapplications with resumes should be directed tothe Chairman of the Search Committee:

Dr. H. GwYWord Steverc/o Carnegle Commission on Science & Technology

1616 P Street, NW, Suite 400Washington, DC 20036

Science Service is an Equal Opportunity Employer.Minorities and women are encouraged to apply.

ASSr./ASSOC.PROFESSOROF BIOLOGYTenure-track faculty position inBiology department available Fall,1991. Ph.D. in Biological Sciencesrequired, with commitment toundergraduate instruction and re-search. Research field open butpreference is for molecular bio-logist. Primary teaching respon-sibilities: laboratory course inintroductory microbiology andupper-level laboratory course invirology or immunology. Possi-bility exists of participating inintro freshman sequence and/orteaching classes for non-majors.Please send vitae, letter detailingteaching and research interests and3 reference letters by January 15,1991 to: Dr. Jonathan Yavelow,Department of Biology, RIDERCOLLEGE, 2083 LawrencevilleRoad, Lawrenceville, NJ 08648.AA/EOE.

For more than a century the employees of BurroughsWelicome Co. have applied their talents to the dscoveryand development of Important new medicines. Theirabilities and initiative have brought our companypreeminence in both thepharmaceutical Industryand thescienfific world.

GREAT PEOPLE MAKEAGREATCOMPANYBile Acid Biochemist

The Section of Blochemical Pharmacobgy in the DMsionof Pharmacokinetics and Drug Metabolism has anopportuntyavailablefora scientisttostudytheenzymokioqyand/or the transcriptIonal control of proteins involved incholesterol catabolism/bile acid synthesis. and their role inthe regulation of cholesterol homeostasis.

Candidates must havea Ph.D. degree In pharmacology,bIochemisty, medicinal biochemistry, or related science;plus one year of postdoctoral expeence or one year ofexperience in cholesterol catabolsm/bIle acid biosynthesisresearch. includng publicatIons.

As a valued professional at Burroughs Wellcome Co. youwill receive a salary commensurate with your experienceand be supported by the highest level of benefits in ourIndustry. If you are interested in working for us, submit yourresume, indicating position number in your cover letter. byJanuary 14, 1991, to: Burroughs Weolom- Co., ScientilcRecruiting and StaffIng, Pos. #62384-4, 3030 ComwallisRoad, Research Tdangl Park, NC 27709.

For information on otherjob opportunItIes with BurroughsWelcome Co.. cal our Jab Infofmaton Uneat (919)248-847.

^ | BURROUGHS WELLCOME CO.Welcome An Equal Opporlunity Employer

IL

ScientistAt Genentech, our success in thebiotechnology indust-y is a resultof superb personnel combinedwith a state-of-the-art environ-ment. To continue our achieve-ments, we are seeking a Scientistin our Medcinal and AnalyticalChemistry department.You will conduct research anddevelopment for the charcteriza-tion of recombinant DNA-derivedpolypeptides. This involves asignificant amount of problemsolving related to productcharacterization using bothchromatographic and spectro-scopic techniques.A Ph.D. in Biochemistry and atleast 2 years of postoctoral studywith a physical or analyticalemphasis is required. Experiencein the evaluation of proteinconfonnation is highly desirable.The ability to conduct independentresearch and good communica-tion skills are essential.Genentech offers an extensivebenefits packge which includeschild care facilities, free healthclub membership, an employeestock purchase plan and fuily paidmedical/denaVvision coverge.For immediate consideraton,please send your C.V. to NancySymonds, Genentech, Inc.,Human Resources Dept NS/ECD,460 Point San Bruno Blvd.,South San Francisco, CA 94080.We actively support and promoteaffinrative action and equalemployment oppotunity. Womenand minorities are encouragedto apply.

Genentech, Inc.Dnm

POSITIONS OPEN

CHAIRPERSONDEPARTMENT OF ANATOMY

AND CELL BIOLOGYNominations and applications are invited for the po-

sition of professor and chairperson of the Department ofAnatomy and Cell Biology at the East Carolina Univer-sity School of Medicine. The department consists of 14full-time faculty and is responsible for the education ofmedical, allied health, and graduate students. The pri-mary research interests are in endocrine physiology/cellbiology, and the neurosciences. The department is wellfunded and well equipped. We are seeking candidateswith an outstanding record of research achievement,proven administrative and leadership skills, and a historyof achievement, proven administrative and leadershipskills, and a history of quality teaching in any of theanatomical disciplines. Candidates should have a doctor-ate in anatomy or a related discipline, experience in anacademic medical center, and a record of scientific excel-lence. Salary and benefits are nationally competitive.Candidates should submit curriculum vitae and thenames and addresses of three references to:

Dr. Paul V. Phibbs, ChairmanAnatomy and Cell Biology Search CommitteeDepartment of Microbiology and ImmunologyEast Carolina University School of Medicine

Greenville, NC 27848-4354Screening for this position will begin on 1 January

1991. An Equal Opportunity/Affirmative Action Universi-ty. Federal Law requires proper documentation ofidentity andemployability at the time ofemployment. It is requested thatthis documentation be included with your application.

DIATOM SYSTEMATISTThe Academy ofNatural Sciences ofPhiladelphia seeks

an outstanding diatom systematist for the career-trackposition of ASSISTANT CURATOR Qualifications:(i) Ph.D. in biology, botany, or dosely related discipline;(ii) comprehensive knowledge of diatom taxonomy andnomencature; (iii) good understanding of ecology andcommunity dynamics as they relate to the taxonomy andsystematics of fieshwater diatoms; (iv) demonstratedexcellence at the postdoctoral level in phylogenetic sys-tematics; (v) ability to attract grant support or indepen-dent research program. Research capabilities that utilizeherbarium collection strengths and complement currentprograms in floristics, eco-taxonomy, and current cladis-tic approaches to centric diatom systematics prefcrred,along with hands-on experience in curation of a diatomherbarium. This position indudes opportunities for ad-junct appointment and graduate students at local univer-sities, especially The University of Pennsylvania. Sendcurriculum vitae, statement of research goals, and namesand addresses of three references by 15 December 1990to: Dr. Charles Reimer, Academy ofNatural Sciences,19th and the Parkway, Philadelphia, PA 19103. AnEqual Opportunity/Affirmative Action Employer.

DEAN OF ARTS AND SCIEENCESKANSAS STATE UNIVERSITY

The dean is an advocate and leader for the college, withresponsibility for programs, budgets, and personnel.Requirements indude a record justifying appointment asa full professor; significant experience in academic ad-minstration; effectiveness as an advocate for diversedisciplines; ability to work effectively with alumni; and aconcern for students, Affirmative Action, and facultyinvolvement in govenance. The position is open 1 July1991, and screening begins 15 January 1991.Send applications to: M. Duane Nellis, Chair, Search

Committee, Anderson Hall 108, Kansas State Uni-versity, Manhattan, KS 66506 with curriculum vitaeand a list of at least three academic references.An Equal Opportunity/Affirmnative Action Employer.

BIOLOGY FACULTYPOSMON; 1991, fall. Ge-netics, cell and molecular biology, tenure track. ASSIST-ANT PROFESSOR, beginning September 1991.Earned doctorate required as well as a strong commit-ment to teaching at the undergraduate level. Apply withrdsum6, graduate transcript, list of publications, descrip-tion of research interests and dtree letters of recommen-dation by 15 January 1991. Send application to: Dr. D.J. Scroede, Department Chair, Biology Depart-ment, College of St. Scholastica, 1200 KenwoodAvenue, Duluth, MN 55811. The College of St. Scho-lastica is a Benedictine liberal arts college, and an Affir-mative Action/Equal Opportunity Employer.

FACULTY POSMONIN BIOCHEMICAL PHARMACOLOGY

The Department of Pharmacology at the University ofAlabama at Birmingham invites applications for a pO-sition of RESEARCH ASSISTANT PROFESSORto complement faculty with research interests in cancer,AIDS, and AIDS-related opportunistic infection. Sendletter of application with curriculum vitae and names ofthree references to: Robert B. Diasio, M.D., Chair-man, Deartment of Pharmacology, Box 600, VolkerHall, Umversity ofAlabama at Birmingh Birming-ham, AL 3529 Equal Opportuniy/Amiative ActionEmployer.

UNIVERSITY OF GUAMBIOLOGYFACULTYPOSMON. ASSISTANT/

ASSOCIATE PROFESSOR to teach at least two ofthe following: genetics, cell physiology, biochemistry,developmental biology, plant diversity, and possibly toparticipate in principles of biology. An initial 3-yearcontract begins August 1991. Ph.D. required. Minimumstarting salary: $33,634 per academic year. Applicationdeadline: 16 January 1991. Submit letter of application,up-to-date resume, official graduate degree transcriptssent directly from awarding institution, unofficial copiesofundergraduate transcripts, three referees, and researchinterests to: University of Guam, Personnel Services,UOG Station, Mangilao, Guam 96923. AnAfllrmativeAction/Equal Opportunity Employer.

COGNITIVE NEUROSCIENCE. DartmouthMedical School is considering four SENIOR FACUL-TY APPOINTMENTS in the broad area of cognitiveneuroscience with particular interests centered on neuro-anatomy, sensory and motor neurophysiology, and neu-robehavior. The new positions will have shared appoint-ments in the Program in Cognitive Neuroscience and inrelevant basic science departments. Interested partiesshould send curriculum vitae to: Dr. M. S. Gazzaa,Department of Psychiatry, Dartmouth MedicalSchool, Hanover, NH 03756.

BIOLOGY. Ph.D. and teaching experience required.Responsibilities include teaching, ielpmg revise curricu-lum, advising students, and serving on university com-mittees. Preference is for a broadly trained person withspecialization toward animal/cellular fields. LeTourneauUniversity is an independent evangelical Christian uni-versity and seeks trained professionals who possess amaturing Christian faith and are committed to the mis-sion of an evangelical residential, Christian university.Send resume to:

Dr. H. Glenn SumrallVice-President for Academic Affairs

LeTourneau UniversityP.O. Box 7001

Longview, TX 75607-7001

TENUREE-TRACK FACULTY POSImTONSCENTER FOR CANCER RESEARCHAND DEPARTMENT OF BIOLOGYMASSACHUSETTS INSTITUTE OF

TECHNOLOGYCandidates are sought for two tenure-track positions,

at the level ofASSISTANT, ASSOCIATE, OR FULLPROFESSOR, in the fields of cell biology and immu-nology.

Candidates should have significant research accom-plishments and should be developing creative approachesto significant problems in contemporary cell biology andimmunology, including the biochemistry and molecularbiology of~~ce cycle control and proliferation, cytoplas-mic organization, antigen recognition, and intracellularsignaling. Faculty members in the cancer center conductactive research programs, and participate in the educa-tional activities of the biology department.

Interested applicants are asked to send curriculum vitaeand bibliography, a briefdescription ofresearch interests,and the names of at least three references to:

Dr. Frank SolomonProfessor of Biology

Cancer Center Search Committee ChairpersonBuilding E17-220

Massachusetts Institute of Technology (MUI)Cambridge, MA 02139

MIT is an Equal Opportunity/Arfirnative Action Em-ployer. Women and members of minority groups are encour-aged to apply.

SCIENCE, VOL. 250

POSITIONS OPEN

POSITIONS OPEN

FACULTYENVIRONMENTAL SCIENCE. The Department

of Urban and Regional Planning at the University ofIllinois at Urbana-Champaign seeks an ASSISTANTPROFESSOR/ASSOCIATE PROFESSOR possible,(tenure track) beginning August 1991. Education andexperience appropriate to the following areas are re-quired; salary negotiable. Joint appointments with relat-ed departments possible. Ecological systems pertinent tohuman settlements; aquatic ecology, hydrology, groundwater, or water quality preferable; research and teachinginterests must develop environmental science findings toplanning; prefer Ph.D. in cnvironmental science, orrelated field.For full consideration send by 7 January 1991 your

curriculum vitae, two examples of our work (papers,course syllabi, design projects), and names, addresses,and telephone numbers of three references to: SearchCommittee, Department of Urban and RegionalPlanning, University of Illinois at Urbana-ham-paign, 907½2 West Nevada, Urbana, IL 61801. Tele-phone: 217-244-5397.The University of Illinois is an Equal Opportunity!

Afllnnative Action Employer.BIOLOGIST. Ph.D. with teaching experience and

primary expertise in cell and molecular biology; to teach12- to 15-hour load, at least half in introductory coursesfor majors and nonmajors. Send letter of interest, curric-ulum vitae, and three letters of recommendation to: Dr.T. 0. Flickema, VPAA, Northern State University,Aberdeen, SD 57401.

FACULTY POSMON INCOMPUTATIONAL CHEMISTRY

The Medicinal Chemistry Department invites applica-tions for a tenure-track ASSISTANT PROFESSORposition. The working environment represents a uniqueopportunity to develop a research prog encompass-ing the application of molecular mod eng to medicinalchemical research and provides an excellent opportunityfor interaction with the Biomedical Engineering Center,the Supercomputer Institute, and with other culty atthe umuversity. Candidates will possess a doctoral degreeand at least 1 year of postdoctoral experience in achemically oriented discipline and have a strong back-ground in semi-empirical quantum mechanics and mo-lecular mechanics as applied to molecules of biologicalrelevance. Experience in 3-D molecular modeling ofsmall molecules and ligand-macromolecular recognitionis essential. The successful candidate will be expected toinitiate an active research program and teach at theundergraduate and graduate levels. Send applicationletter, resume, proposed research program, and the ad-dresses and telephone numbers of three references by 15February 1991 to: Professor Philip S. Porto.hse,Department of Medicinal Chemistry, Universit ofMinnesota, 308 Harvard Street S.E., MinneapoLisMN 55455. The University of Minnesota is an EqualOpportunity Educator and Employer, and specificaily invitesand encourages applicationsfrom women and minorities.

BIOLOGY DEPARTMENT at Hartwick Collegeseeks an ECOLOGIST for a full-time, tenure-trackposition beginning September 1991. Commitment toundergraduate teaching and Ph.D. is required. Respon-sibilities incude teaching ecology (upper-level course formajors), evolution, animal behavior, forest ecology, anda course in area of expertise, and to direct undergraduateresearch in ecology. A strong statistical background ispreferred. Send letter of appfcation, resume, and threeletters of reference by 4 January 1991 to: Dr. RobertR. Smith, Chair, Department of Biology, HartwickColiege, Oneonta, NY 13820. An Equal OpportunityEmployer.

More than150,000 eople

paito see your ad

in

SCIENCEClassified Advertising Department

Telephone: 202-326-6555FAX: 202-682-0816

30 NOVEMBER 1990

Scientists

M/l ebbakisn

Takeact,iON

ta.harmaceiitcaIrsearchand'diwoum1ewf-5-- -

The time is now to contribute towards our leadership in develop-ment of new pharmaceuticals. As a highly recognized division ofa $3+ billion health care company, Schering-Plough Researchis extending the limits of medical knowledge. Our search forhuman and veterinary pharmaceuticals that provide significanttherapeuticadvantagesfora wide range of diseasesisour primaryscientific objective. If you're a broadly experienced scientistwho shares our goals and vision, there's a challenge awaitingyouat our Bloomfield and Lafayette, NJ research facilities.Senior/Principal Scientists (*DS-90-17/18)Responsibilities will include supervising a small staff of scien-tific personnel. To qualify, the Senior Scientist must have 0-3years' post-doctoral experience and the Principal Scientist musthave 5 years! post-doctoral experience in Biochemistry,Chemistry (Organic, Analytical, Medicinal), Pharmacy orrelated disciplines. A strong background in research areas suchas biopharmaceutics, analytical methods development, in-strumentation, in-viw and 4n-vitro drug metabolism techniques,including metabolite isolation and identification, and the abilityto apply this expertise to independent projects are essential. Ex-cellent orpl and written communication skills required.Assistant Scientist (DS-9014)To qualify, you must have either a BS or MS inChemical/Biological Sciences and 0-4 years' relevant ex-perience. A strong background in modern analytical techniquesincluding GLC, HPLC, TLC is required.We offer an excellent salary and benefits package. For im-mediate consideration, please send your resume to: Mr. G.Czuba, Schering-Plough Research, 60 Orange Street, Bloom-field, NJ 07003. We are an equal opportunity employer.Whbatyobhaveinmin4,Vwepatk#foactfio

9i; Schering-Plough

I

//RESEARCHOPPORTUNITIES

IN MOLECULAR ANDCELLULAR BIOLOGY

Amgen, a recognized and innovative leader in thediscovery and development of human therapeuticproducts through applied biotechnology, is activelyseeking scientists at BS, MS and Ph.D. levels toconduct research within our Colon Biology pro-gram. The objectives of this program will bedefining, isolating, cloning and characterizingprotein factors involved in the growth and differenti-ation of the colonic epithelium.

RESEARCH SCIENTISTS Dept. #549Candidates for Research Scientist positionsmust have a Ph.D. in molecular or cellular biol-ogy and 2 to 5 years' relevant postdoctoralexperience. Candidates must have a strongpublication record reflective of their achieve-ments.Applicants for Molecular Biology positionsshould have a strong foundation inmolecular biology and related techniquesincluding the construction and screening ofcDNA libraries. Experience in expressioncloning is particularly valuable.Candidates for Cellular Biology positionsmust have experience in bioassay develop-ment and protein purification. This inves-tigator will be responsible for establishingappropriate bioassays for growth and/or dif-ferentiation factors and participating in theirisolation and characterization. Experiencein intestinal epithelium is particularlydesirable.POSTDOCTORAL SCIENTIST Dept. #550Candidates for postdoctoral positions musthave a Ph.D. in molecular biology or arelated discipline and be familiar withroutinely used methodologies in cDNAcloning.RESEARCH ASSOCIATES Dept. #551

Minimum qualifications for these positionsinclude a BS in an appropriate field with twoyears' research experience in molecularand cellular biology. Experience in basicrecombinant DNA methodologies and cellculture techniques is highly desirable.

Amgen offers a stimulating and challengingresearch environment on the leading edge ofbiotechnology. Our need for these positions reflectsan ever increasing commitment to the developmentof significant products for human health carethrough excellence in research.If you have the necessary skills and would like to bea part of an organization that places a high priorityon its human resources, please send a completeCV, in confidence, to:AMGEN, INC.Recruitment, Dept. # (please specify)Amgen CenterThousand OaksCA 91320-17897EqualOpportunity IErermwly

Wyeth-Ayerst is a recognized world leader in the produc-tion of a wide range of highly advanced pharmaceuticals.We currently have an opportunity for a PostdoctoralScientist to join our Microbiology and BiotechnologyDivision in Radnor, PA, an ideal location just outside ofPhiladelphia.Become an integral member of our research teaminvolved in vaccine and/or CNS research. We want to talkwith you if you have a Ph.D. in immunology, biochem-istry, or a related field with experience in immunologictechniques, protein purification and tissue culture.Wyeth-Ayerst offers an attractive salary and benefitswhich are immediately available for a one year appoint-ment, and can renewed for another year. Qualified candi-dates are invited to submit curriculum vitae to:Recruitment Manager, Wyeth-Ayerst, ResearchPersonnel, P.O. Box 8299, Philadelphia, PA 19101.Equal Opportunity Employer, M/FIH/V, responsesencouraged. Principals Only.

Faculty Positions In

Applications are invited for tenure track faculty positions atthe Assistant Professor level. Successful candidates willoccupy new laboratories on the neurobiology floor of theOhio State Biotechnology Center and hold an academicappointment in the College of Biological Sciences,Medicine or Pharmacy. Applicants should demonstrateexceptional potential to develop strong research programsthat apply recombinant DNA methodology to address sig-nificant problems in neurobiology. The Ohio StateUniversity has made a major commitment to establish anoutstanding interdisciplinary program in molecular neuro-biology that is reflected by the quality research facilitiesand highly competitive start-up funds and salary thataccompany these faculty positions. The Ohio StateUniversity is the flagship institution of the State higher edu-cation system. It is located in Columbus, the state capital, agrowing, yet highly affordable metropolitan area of about1.3 million people that was recently named by Newsweekmagazine as one of the country's top 10 cities.Applicants should submit a curriculum vitae, statementof research plan and names, addresses, and telephonenumbers of three references by January 15, 1991 to: Dr.

Anthony Young, Chairperson,Molecular Neurobiology

THE Search Committee, Ohio StateBiotechnology Center, 207OHIO Rightmire Hall, 1060 CarmackRd., Columbus, OH 43210. TheSTATE Ohio State University is an

UNIVERSITYwrDC sv Equal Opportunity/AffirmativevUNIVERSTYs Actio'n Employer.

Project LeadersScience and TechnologyThe New York Blood Center has excellent positionsavailable immediately in the following areas:

Project Leader/Hematology and Cell BiologyPh.D. in Cell Biology, Pathology or related areas with aminimum 2 years of post-doctoral experience. Tissueculture experience necessary. Publications.

Project Leader/Virology and Molecular BiologyPh.D. in Molecular Biology or Virology with a minimum2 years of post-doctoral experience. Publications.

This laboratory is dedicated to Research and Developmentof technologies applied to Transfusion Medicine. Thepositions entail project management, laboratory admin-istration, experimental work, publications.

There is extensive opportunity for interaction with theResearch Staff and Operations Staff of the New YorkBlood Center.

In addition to working within a stimulating environment,we offer the right individuals 5 weeks vacation, 100%tuition reimbursement, medical/dental coverage andexcellent pension plans. Qualified applicants are invitedto submit CV and references to: The New York BloodCenter, Research/Human Resources, 150 AmsterdamAve., NY, NY 10023. Equal opportunity employer M/F

ANewYork Blood CenterWhere concern for the communitY comes first.

AN EQUAL OPPORTUNITY EMPLOYER

DEPARTMENT OF THE ARMY JOB VACANCY

ELECTRONICS ENGINEERThe U.S. Army Research Office (ARO), located in Research Triangle Park,North Carolina, is seeking a highly qualified Electronics Engineer to serve asAssociate Director of the Electronics Division. This is a Civil Service positionat the GS-15 grade level with a salary range of $59,216-$76,982 per annum.

The incumbent will share with the Director the responsibility for directing abroad program of research in the field of electronics including monitoringprogress of Division activities towards program goals, proposing resourcedistribution, representing the Electronics Division at briefings and seminarsto insure the effective interchange of scientific knowledge, participating instudies and committees assessing technical areas of importance to ARO andintegrating knowledge into the formulation of program plans and objectives.Incumbent will also act as Program Manager for an external contract researchprogram in one or more electronics subfields: micro-electronics; physicalelectronics and opto-electronics; circuits and signal processing; and anten-nas and electromagnetic detection. The incumbent will identify new researchopportunities, communicate ARO interests to the scientific community,evaluate and select research proposals for funding, manage availableresources, and communicate research results to appropriate Army activities.

In addition to the basic requirement of a bachelor's degree in engineering,applicants must have one year of specialized experience in electronicsengineering equivalent to the next lower grade in the Federal Service and abackground in fundamental research. Applicants should possess (1) Abilityto plan, direct and guide a research program in electronics engineering;(2) Ability to evaluate research proposals for technical merit; (3) Advancedknowledge of one or more subfields of electronics engineering and evidencethat technical competence has been maintained; (4) Ability to interact effec-tively with other scientists, professional groups and management officials;and (5) Ability to review and evaluate program implementation and results.

Applicants should submit a Standard Form 171, Application for Federal Em-ployment (available at Federal Job Information Centers and Federal PersonnelOffices) and a supplemental statement which addresses each qualificationlisted above to: U.S. Army Research Office, ATTN: SLCIS-CP-AR, P.O. Box12211, Research Triangle Park, NC 27709-2211. For further information, call(919) 549-0641, extension 212. Applications must be received by December31. 1990.

Institute for Biomolecular ScienceUniversity of South Florida

GRADUATE FELLOWSHIPS(MULTIDEPARTMENTAL)

* MOLECULAR VIROLOGY AND IMMUNOLOGY* MICROBIOLOGY* BIOTECHNOLOGY* BIOCHEMISTRY & MOLECULAR BIOLOGY* CELL BIOLOGY

The UNIVERSITY OF SOUTH FLORIDA has recently estab-lished an INSTITUTE FOR BIOMOLECULAR SCIENCE withemphasis on research in the above areas. Fellowships in-clude $12,000 stipend PLUS tuition waiver PLUS travel toa national meeting. For further information contact:

Dr. Daniel V. LimInstitute for Biomolecular ScienceUniversity of South FloridaLIF 169Tampa, FL 33620-5150

U.S. CITIZENSHIP REOUIRED

NPOSITIONS OPEN

MATHEMATICAL STATISTICIAN

To develop design of finite element model of humanbrain and skull, and design algorithms for solving equiv-alent dipole models and conduct simulation studies.Candidate must have Ph.D. degree in mathematicalstatistics or related field and working knowlcdge ofUNIX. Experience with electromagnetic theory would behelpfil. Please send rvsumi to: Box 135, SCIENCE.

POSTDOCTORAL POSMONS. Available in theareas of molecular, cell, and developmental biology.Applicants should send curriculum vitae, references, anda brief description of research interests to: The Postdoc-toral Program, EC/Department of Molcular Biolo-gy, LewisThomas Laboratory, Princeton University,Princeton, NJ 08544. Princeton University is an EqualOpportunity/Aflirmative Action Employer.

POSTDOCTORAL POSMON. For 2 years inalcohol research available immcdiately. Studies includethe hormonal rcgulation of expression of genes involvedin ethanol metabolism, purification and molecular don-ing of factors controlling expression of the same genes.U.S. citizen or permanent resident. Send letter of applica-tion and curriculum vitae to: Esteban Mezey, M.D.,Professor of Medicine, The Johns Hopkins Universi-ty, Hunt. 415, 725 North Wolfc Steet, Baltimore,MD 21205.

POSTDOCTORAL ASSOCIATES. Two positionsare available to study fungal (1-3) P-glucan synthase.Research will involve purification of enzyme activity aswell as molecular donng of the relevant genes. Experi-ence with protein pu cation or molecular biology isessential. Please submit curriculum vitae with names ofreferences to: Dr. C. Selitrennikoff, Department ofCellular and Suctural Biology, University of Colo-rado Health Sciences Center (UCHSC), 4200 East9th Avenue, B-111, Dcnver, CO 80262. UCHSC isan Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL TRAINEESHIPTwo NIH/NRSA-funded postdoctoral positions are

available in the Molecular Medicine Program, LawrenceBerkeley Laboratory, to conduct lipoprotein and ather-osclerosis research. Project areas include gene expressionin transgenic mice, mechanisms of lipoprotein oxidation,and celf biology of reverse cholesterol transport. Re-quires a recent Ph.D. in molecular biology or cellularbiology as appropriate. Applicants must be U.S. citizens orpermanent residents. Send curriculum vitae and the namesand addresses of three references to: Dr. Ronald M.Krauss, Program Leader, Molecula Medicine Pro-gram, Lawrence Berkeley Laboratory, Donner Labo-ratory, 1 Cyclotron Road, Berkeley, CA 94720. Af-firmnative Action/Equal Opportunity Employer.

THREE POSTDOCTORAL POSMONS. Avail-able immediately on NIH Training Grants to studymolecular mechanisms of chemical and viral carcinogen-esis and molecular, cellular, and immunological aspectsof eukaryotic gene control. The program is situated inthe newly constructed Norris Cancer Center which con-tains state-of-the-art microchemical, microinjection, flowcytometry, pharmacoanalytical, cell culture, and comput-er core facilities. Training faculty are: Dan Broek (Reg-ulation ofoncogene function); Robert Deans (Mokcularbiology of B cell activation); Gunther Dennert (Molec-ular and cellular immunology); Yuen K. T. Fung (retin-oblastoma); Myron Goodman (biochemical mechanismsof fidelity and SOS repair); Peter A. Jones (tumor cellbiology; DNA methylation); Joseph R. Landolph (mo-lecular biology of chemical transformation); Amy Lee(molecular biology; control of mammalian gene expres-sion); Rob Maxson (Gene regulation during early devel-opment); Minnie McMillan (Role of MHC complex);Mark Moore (Molecular immunology); Chi Nguyen-Huu (Transgenic mice/homeobox); Suraiya Rasheed(retroviruses; AIDS-related lymphomas); Pradip Roy-Burman (retroviuses and oncogene alleles); Peter K.Vogt (Oncogenes). Candidates must be U.S. citizens orpermanent residents, Minority and women candidates arestrongly encouraged to apply. Send curriculum vitae, threeletters of recommendation, and preference of facultypreceptors to: Dr. Joseph R Landolph, Kennth Nor-ris Jr. Comprehensive Cancer Center/USC School ofMedicne, 1441 Eastake Avenue, Los Angeles, CA90033. Affirmative Action/Equal Opportunity Employer.

1302

POSIDOCTORAL POSMON. With research di-rected at the pathophysiology of uremic growth failureby using cellular and mo[ecular biology techniques.NIH-supported. Restricted to U.S. citizens and perma-nent residents. Candidates should send curriculum vitaeand three references to: James C. M. Chan, M.D.,Medical College ofVirginia, Station Box 498, Rich-mond, VA 23298-049S. Equal Opportunity/lAnmativeAction Employer.

POSTDOCTORAL POSMONAvailable immediately to study the role of carcinogen-

DNA interactions in carcinogenesis. Experience withanimals or cell cultures preferred. Candidates should behighly research motivated. Please send curriculum vitae,summary of research accomplishments, and names ofthree references to: Dr. Ramesh Gupta, PreventiveMedicine, 308 Funkhouser, University of Kentucky,Lexinon, KY 40406.

POSTDOCTORAL POSMIION. To study expres-sion and function of unique sulfated oligosaccharidesfound on pituitary glycoprotein hormones. Projects di-rected at cloning glycosyltransferascs responsible foroligosaccharide synthesis and defining their functionalsignificance for sorting to storage granules and hormonebioactivity. Experience in molecular biology and/or bio-chemistry is essential. Send curriculum vitae and refer-ences to: Dr. Jacques U. Baenziger, Washington Uni-versity Medical School, Department of Patholoan,660 South Euclid Avenuc, St. Louis, MO 631 -FAX: 314-362-8888.

POSTDOCTORAL POSMON. Available for in-vestigating the molecular/genetic basis of DNA strandbreak repair in mammalian cells using various repairdeficient mutants. One year of recent experience inmolecular biology and/or biochemistry prefrred. Weoffer a competive salary and benefits package. Sendstatement of research interest, curriculum vitac, and threereferences to: Dr. Ihomas D. Stamato, The LankenauMedical Research Center, Lancaster Avenue west ofCity Line, Philadelphia, PA 19151-0598, or call:215-645-8400. Equal Opportunity Employer. A memberof the Main Line Health family of hospitals.

POSTDOCTORAL POSMIION. Available imme-diately, for up to 4 years, to study stress-induced alter-ations in rat brain serotonergic function, to define neu-rotransmitter and stcroid mediators and the molecularbasis for the stress-induced biochemical changes withinserotonergic neurons. Project uses neurochemical, phar-macological, and stereotaxic approaches. Send curricu-lum vitae and names of three references to: Dr. M. C.Biber, Department of Physiology, Medical Coliege ofVirginia, Virgnia Commonwealth Universityv Rich-mond, VA 23298-0551. Equal Opportunity/AfllrativeAction Employer.

POSTDOCTORAL POSMONHOST DEFENSE/NEUTROPHIL BIOLOGYPosition is available to study mechanisms underlying

the synergistic action of IgM antibodies and the alterna-tive complement pathway in promoting bacterial phago-cytosis and killing by neutrophils U. Exp. Med. 164,777; Rev. Infect. Dis. 12, S161). There is opportunityfor promotion to junior faculty status. Training in phag-ocyte biology is desirable. Send curriculum vitae andnames of three references to: Dr. Ann Bjornson, Direc-tor, Division of Immunology, James N. Gamble In-stitute of Medical Resach, 2141 Auburn Aveue,Cinnati, OH 45219. An Equal Opportunity Employer.

The Basic Scicnce Departments (Cell Biology andNeurana, Biochemistry, Microbiology, PathologyPharmacology, Physiology), Medical School, Universityof Minnesta, periodically have openings for POST-DOCTORAL TRAINIG.For information about possible openings in dtese

programs, write, specifring department of interest, to:University of Minnesota Medical School

Box 293 UMHC420 Delaware Stret, S.E.Minneaolis, MN 55455

Attention: James C. NelsonThe University of Minnesota is an Equal Opportunity

Educator and Employer and specfically invites and encouragesapplicationsfrom women and minorities.

BEATRICE WATSON PARRENTPOSTDOCTORAL RESEARCH FELLOWSHIPThe Institute for Astronomy, University of Hawaii,

solicits applications for the 1991 award of the BeatriceWatson Parrent Fellowship in Astronom, which issupported by endowed funds. The successfl applicantwillbebased in Honolulu, and will be free to pursue theresearch area of her/his choice without functional dutiesor other obligations. Observational facilities indude theUH 2.2-m and 0.6-m telescopes, the 3.6-m Canada-France-Hawaii Telescope, the 3.8-m United KingdomInfrared Telescope, the 3-m NASA-IRFT, the 15-mJames Clerk Maxwell Telescope, the 10-m Caltech Sub-millimeter Telescope, the Mees Solar Observatory, andthe LURE lunar and satellite ranging observatory. Com-puting facilities at the Institute for Astronomy indude anetwork of Sun4 and Sun-3 class machines, plus accessto the San Diego Supercomputer Center.

Applications are sought from recent or imminentPh.D. recipients of high standing in any field of astron-omy or astrophysics. Appointment will be initially for a2-year period, beginning September 1991, with the

possibility ofrenewalfo third year. Annual stipend willbapproximately $33,500, with possibility of increasesubject to authorixation. A rescarch budget will beavailable to the appointee. Additional information maybe obtained from: Dr. David Jewitt, telephone: 808-956-6664. To apply, send a letter describing researchachievements and scientific goals, curriculum vitae, and abibliography to: Dr. Donald Hail, Director, Institutefor Astronomy, 2680 Woodlawn Drive, Honolulu,HI 96822. Three leters of recommendation should besent directly to the director. All applications must bereceived, complete, at the Institute for Astronomy by 31December 1990. Equal Opportunity/Affirmative ActionEmployer.

WllLS EYE HOSPITALTHE P. ROBB McDONALD, M.D.AND DAVID MEYER, M.D.

POSTDOCTIORAL RESEARCH FELLOWSHIPSAvailable immediately for studies in ocular inflamma-

tion and tumors. Research experience in molecular biol-ogy necessary. Send curriculum vitae and names of tworeferences to: Joyce D. Fuhrman, Wills Eye Hospital,Research, 9th and Walnut Streets, Philadelphia, PA19107.

POSTDOCTORAL FELLOWSHIPSCALIFORNIA PARKINSON'S FOUNDATIONThe California Parkinson's Foundation invites appli-

cants for postdoctoral fellowships for 1991. Researchprojects are aimed at elucidating the molecular basis ofneurodegenerative processes. Biochemical and toxicolog-ical studies applied in the field of neuroscience wilinvolvc analysis of the effects of drugs and potentialenvironmental toxicants in different model systems usingtechniques such as tissue cultures, GC/MS, HPLC, andPCR. Applicants with training in pharmacology, toxicol-ogy, or biochmistry are invited to send their curriculumvitae and names of three references to: Dr. J. WilliamLangsto, Califoia Parkinsn's Foundation, 2444Moorpark Avenue, Suite 316, San Jose, CA 95128.

The Day Neuromuscular Research Center at the Mas-sachusetts General Hospital (MGH) (Harvard MedicalSchool) in Boston, Massachusett, has an immediateopening for aPOSTDOCTORAL FELLOW and tech-mcian in investigations of defective human genes under-lying famiial forms of amyotrophic lateral sclerosis. Theproject entails a wide range of methodologies includinginkage analysis using anonymous DNA markers, prepa-ration and mapping of cosmids and new probes fromselected chromosomal regions, and PCR analysis ofhighly polymorphic regions of DNA in ALS pedigrees.The studies will encompass both conventional linkgedata analysis and nove linkage strategies such as ho-mozygosity mapping. The project is directed collabora-tively by Drs. R. Brown (Day Neuromuscular ResearchLaboratory, MGH), J. Gusella (Neurogenetics Unit,MGH), and R. Horvitz (Biology, Massachusetts Insti-tute of Technology). The laboratory is located in a newfacilit in the Neuroscience Center in Charlestown. Ex-cellent technical back-up is available. The MassachusettsGeneral Hospital is an Equal Opportunity Employer. Pleasecontact: Dr. Bob Brown; telephone: 617-726-5750.

SCIENCE, VOL. 250

POSITIONS OPEN POSITIONS OPEN

National Institutes of HealthResearch Scientist

and Postdoctoral Fellows

TASTE AND SMELLResearch Scientist (D.M.D., M.D., Ph.D., D.D.S.)sought to head a new research project on Taste andSmell. Areas of investigation will include the natureof the cell surface receptors, mechanisms of signaltransduction and membrane channels. Training inmolecular biology, protein chemistry and cell biologyis desirable. Positions for post-doctoral fellows alsoare available. Salary is commensurate withexperience. Send Curriculum Vitae and names ofreferences to:

Dr. Lois Salzman, Deputy DirectorIntramural Research ProgramNational Institute of Dental ResearchNational Institutes of Health9000 Rockville Pike 1*,Building 30, Room 121 I -

Bethesda, MD 20892

NIH is an Equal Opportunity Employer

Environmental MicrobiologistApplications are invited for a tenure-track position atthe Assistant Professor level in the Department ofBiology beginning fall 1991. The Department is seek-ing a person to develop an Environmental StudiesProgram and related courses such as aquatic biologyand toxicology and teach an introductory microbiolo-gy course. The candidate should have a Ph.D. inMicrobial Ecology/Environmental Microbiology or en-vironmentally related area, have a strong commit-ment to undergraduate teaching, and have a desire todevelop a research program with undergraduates.Grant writing experience is desirable but not neces-sary. Minorities and women are encouraged to apply.

To apply, submit letter of application, curriculumvitae, description of research interests, transcripts,and three current letters of reference by January 15,to Martha A. Farver-Apgar, Director of Personnel,Elizabethtown College, One Alpha Drive, Elizabeth-town, PA 17022.

AA/EO

UNIVERSITY OF VIRGINIAThe Markey Center

for Research on Cellular Signaling Procesm

Faculty Positions in:Structure of Cell Membranesand ReceptorsSignal Transmission and Processing,including second messengers

Signal-initiated Regulation ofGene ExpressionPertinent Macromolecular Structures

Research in these areas is supported by univer-sity-wide, multidisciplinary programs of the Mo-lecular Biology InstiMte, the Biodynamics Insti-tute, and the university's newly-organized andfunded Markey Center. Several new positionswill be filled in each of the coming three years.Emphasis is upon assistant Professorships, butsenior appointments are also planned.

Applications and nominations from qualified sci-entists are cordially invited. Applicants shouldprovide a full academic and research r6sum6and the names and addresses of three referees.Please write to:

Markey Center Search CommitteesCenter for Advanced StudiesUniversity of VirginiaCharlottesville, VA 22903-3196

The University of Viinia is an Afirmative Action,Equal Opportunity Employer.

B I O LO G YThe Department of Biology at the University of

Southwestem Louisiana (enrollment, 16,000) invitesapplications for three tenure-track positions in supportof the doctoral program in Environmental and Evolu-tionary Biology. Faculty are expectqd to develop anactive research program, participate in undergraduateand graduate education, and direct graduate research.The biology professorial faculty currently numbers 27with research interests ranging from molecular toecosystem studies. USL has an exceptionally well-equipped Electron Microscopy Center and a Center forAdvanced Computer Studies. Other resources includethe Primate Research Center, the Center for Crusta-cean Research, the Louisiana Universities MarineConsortium (LUMCON) marine laboratory and re-search vessels, and affiliation with the U.S. Fish andWildlife Service's National Wetlands Research Center.The department has recently been awarded top ratingsby an outside panel of nationally prominent reviewers.We are seeking qualified individuals in the following

areas:

CELLULAR or NEUROBIOLOGY - research interestsprimarily non-medical; ability to teach undergradu-ate immunobiology.

ENVIRONMENTAL and RESOURCES BIOLOGY - re-search interests may include, but are not limited to,remote sensing, landscape modelling and restora-tion, wildlife population dynamics and nutrition,and biodiversity, especially in coastal wetlands.

TOXICOLOGY - research interests in toxicology offreshwater or marine systems.

Send curriculum vitae, selected reprints, a concisestatement of research goals, and names, addressesand telephone numbers of three referees. Review ofapplications will begin 15 January 1991 and continueuntil positions are filled. Direct application to: FacultyDevelopment Search Committee, Department of Biolo-gy, University of Southwestem Louisiana, Lafayette,LA 70504-2451. AA/EOE.

RESEARCHSCIENTIST

Berwick Corporation, a rapidlygrowing biotechnology Com-pany has an excellent oppor-tunity available for a researchscientist at its Warminster, PAfacility in suburban Philadelphia.You will be involved in product

development and technicalmarketing support for the nucleicacid purification product line ofthe company's Life ScienceDivision. You will have a strongbackground in biochemistry,molecular biology or geneticsand experience in HPLC, gelelectrophoresis, and recom-binant DNA techniques.The successful candidate will

have a Ph.D in a life science, ex-cellent verbal, written and inter-personal communication skills.We offer a competitive salary andcomprehensive benefit program.For consideration, please forwardyour resume, with salary require-ments to: Berwick Corporation,Box 2548, Warminster, PA 18974.

SMITHSONIANPOSTDOCTORAL FELLOWSHIPSIN MOLECULAR EVOLUTIONAND PLANT PHYSIOLOGY

Postdoctoral fellowships in molecular evolution andplant physiology are available for rescarch to bc conduct-ed at onc or more of the following Smithsonian Institu-tion bureaus: National Muscum of Natural History(Washington, D.C.); National Zoological Park (Wash-ington, D.C.); Smithsonian Tropical lLesarch Institute(Panama). In addition, a portion of the rcseareh may beconducted at the Smithsonian Environmcntal RcsearchCenter (Maryland). Stipends are $24,000 annually, in-duding travel. Tcnures are from 12 to 24 months.Dcadlinc: 15 Fcbruary 1990. For information and appli-cations, write: Office of Fellowships and Grants, DeskMS, Smithsonian Institution, Washington, DC20560.

POSTDOCTORAL RESEARCH TRAININGFELLOWSHIPS in endocrinology, metabolism, diabe-tes for M.D. or Ph.D. graduates are available at EmoryUniversity School of Medicine utilizing eleven trainingfaculty in six basic and clinical departennts. Must be U.S.national orpervnanent resident. M.D. applicants must haveU.S. residency experience. Send curriculum vitae, state-ment of rescarch and career objectives, and two letters ofreference to: Lawrence S. Phillips, M.D., ProgramDirector, Emory Univerity School of Medicine, 69Buter Street, S.E., Atlanta, GA 30303. An EqualOpportunity Employer.

RESEARCH FELLOWSHIPSPositions available in basic research (ccll biology,

molecular biology, biochemistry, physiology). M.D.'s,M.D.-Ph.D.'s, and Ph.D.'s cligibl. Must be U.S. citizenor petnanent resident. Contact: William R. Brown,M.D., Gastroenterology Division, B-158, Universityof Colorado School of Maicine, 4200 East Ninth-Avenue, Denver, CO 80262; telephone: 303-399-8020, cxt. 3130; FAX: 303-320-0608. The Universityof Colorado is an Equal Opportunity/Affirmative ActionEmployer.

MOLECULAR TUMOR BIOLOGYPOSIDOCTORAL/RESEARCH ASSOCIATE

POSMTION. Availablc immediately for candidate withbackground in one or more of the following areas:molecular biology, genetc engineering, virology, immu-nology, biochemistry, or radiation biology. Candidatewill participate i research on the oncogenic mechanismsand growth control of radiation-resistant human cancers.Ongoing projects involve antisense-directed gene inhibi-tion strategy, signal transduction, and PCR-based evalu-ation of the oncogene function in normal versus tumorcells. Please send curriculum vitae to: Dr. U. Kasid,Associate Professor, Depart of Radiation Medi-cne, The Vincent T. Lom i Cancer ResearchCenter, Georeown University Medical Center,3800 Reservoir Road, N.W., Washington, DC20007. Equal Opportunity/Affirnative Action Employer.

RESEARCH ASSOCIATE. For university in north-eastern Ohio. To conduct advanced research on liquidcrystals using deuterium NMR specroscopy. The re-search encompasses the following three projects: to studythe effects of confinement (cylindrical and spherical cav-ities) on liquid crystal, surface-induced orientational or-der, and phase transition and self-diffusion of liquidcrystal; to study the elecoptical properties of poly-mer-dispersed liquid crystal, using laser light scattenngtechnique; and to do computer simulation of textures ofpolymer-dispersed liquid crstal droplets andNMR spec-trum of liquid crystal. Must have Ph.D. in physics andacademicprogram must have included one course each inquantum m&hanics, statistical physics, advanced theoret-ical physics, solid-state theory, advanced optics, andcondensed matter physics. Must have ability as evidencedby academic course work and/or publications and/oremployer testimonials to conduct research using deute-rium NMR spectroscopy and to do computer simula-tions of the behavior of polymer-dispersed liquid crystal.Forty hours per week, 8:30 a.m. to 5:30 p.m.; $22,500per year. No experience required. Must have proofoflegalauthority to wor1 permanendy in the United States. Sendresume and course transcript in duplicate (no calls) to: J.Davies, JO# 1242008, Ohio Bureau of EmploymentSerices, P.O. Box 1618, Columbus, OH 43216.

POSTDOCTORAL RESEARCH ASSOCIATEIN AQUATIC BIOLOGY. Available immediately tostudy toxic substances and microbial, fisheries, or zoo-plankton ccology. Experience in the flux of toxic sub-stances is particularlv desirable. The successful applicantwill participate in funded Great Lakes and watershedprograms and have the opportunity to develop indepen-dent research allied to these projects. Salary: $25,000. Toapply, please send rEsumI, sumnary of research experi-ence,publications, and names of three references to: Dr.Ronald Ward, Water Resources Institute, Grand Val-ley State University, Allendale, MI 49401. EqualOpportunity/Affirmative Action Employer.

The U.S. Department of Agriculture (USDA), Agri-cultural Research Service (ARS), Food and Feed SafetyResearch Unit, Southem Regional Research Center(SRRC), is seeking a POSTDOCTORAL RE-SEAARCH ASSOCIATE to work for 2 years with ateam developing techniques to alter populations of As-pergillusflavus m agricultural fields. The work may in-dude fundamental and applied aspects of the project.Some knowledge of serology and/or molecular biologywould be uscful. Scale: GS-11 ($29,891). For infomna-tion on the research program, contact: Dr. Peter J.Cotty, USDA-ARS, SRRC, P.O. 19687, Ncw Or-leans, LA 70179. Telephone: 504-2864391. Forprocedures/forms, contact: Judy Harrington, 301-344-1506. Mark responses S-0-010. USDA is an EqualOpportunity/Afirmative Action Employer.

POSTDOCITORAL RESEARCH ASSOCIATEA postdoctoral position is available 1 January 1991 to

study microtubule assembly dynamics in the vertebratebrain (at the University of Kansas) and the squid giantaxon (at the Marine Biological Laboratory, Woods Hole,Massachusetts). Projects involve biochemical, cellular,and video-enhanced optical approaches to identify andcharacterize endogenous inhibitors of microtubule as-sembly and/or regulators of dynamic instability. Candi-dates should have a Ph.D. and experience in relevanttechnologies. The salary range for this position is$22,000 to $26,000 depending upon experience. Pleasesend curiculun vitae, brief statement of research expe-rience and interests, and three letters of reference to: Dr.Kathy A. Suprenant, Department of Physiolo andCell Biology, 4010 Haworth Hall, Univcrsityof0Kan-sas, Lawrence, KS 66045. Equal Opportunity Employer.

POSIDOCTORAL RESEARCH POSMONS.Available to study the toxic effects of ethanol on biolog-ical systems. The focus is on molecular and biochemicalmechanisms of cellular toxicity using tissue culture cellsas a model. The well-funded, productive laboratory is

of a diverse interdisciplinary group including NIH-ded liver and alcohol centers investigating basic mech-

anisms of cellular injury. Strong background in cellularphysiology and practical experience in tissue culture isrquired. This iS an excellent opportunity for diversecollaborations and to develop experse in molecularbiology techniques. Competitive salry. Send curriculumvitae and names of three references to: Sharon Taylor,University of Colorado Health Sciences Center, He-patobiliary Center, Box B158, 4200 East 9th Avenue,Denver, CO 80262. Equal Opportunity/Affirmative Ac-tion Employer.

ASSOCIATE RESEARCH SCIENTISTNontenure-track research positions available in the

Department of Physiology and Cellular Biophysics. Can-didates mustposessM.D. or Ph.D. degree and at least 3years of postdoctoral experience. Areas of interest are (i)biochemical studies of endothelial biology, requiringexperience in hybridoma antibody production, proteinchemistry, and cell culture; (ii) studies of the earlyembryological development of the mammala centralnervous system, requring experience in embryologicaltechniques, molecular biology, immunohistochemistry,and protein biochemistry; and (iii) studies of molecularmechanisms of inflammation involving membrane bio-chemistry, cell, and molecular biology, requiring experi-ence in membrane biochemistry, cell, and molecularbiology. Send application with full curriculum vitae to:Dr. Samuel C. Siilverstin, Chairman, Department ofPhysiology and Cellular Biophysics, Columbia Uni-versity, 630 West 168th Street, Ncw Yorkc, NY10032. Columbia University is an Affirmative ActionlEqual Opportunity Employer.

Senior StaffFellowship

Senior Staff Fellowship in clinical psychiatryand molecular genetics, Clinical NeurogeneticsBranch, NIMH Intramural Program. Openingfor a psychiatrst or other behavioral scientistwith experience in molecular scanningmethods, particularly denaturing gradient gelelectrophoresis, and clinical psychiatricgenetics, including linkage studies, to pursueinvestigations on disease mutations andlinkage in medical disorders, includingpsychiatric disorders such as schizophrenia,manic-depressive illness, Alzheimers disease.

Requirements: M.D. and at least threeyears of psychiatnc residency, and at least oneresearch fellowship experience related to thisposition, or equivalent doctoral training, dinical,and research experience in another relateddiscipline. U.S. citizenship or permanentresidency.

Salary: depends on education andexperence. Federal salary range for SeniorStaff Fellowships is $32,000 to $54,727.

Contact: Elliot S. Gershon, M.D.,Chief, Clinical Neurogenetics Branch,National Institute of Mental Health,National Institutes of Health, Building10-3N218, 9000 Rockville Pike,Bethesda, Maryland 20892; Phone:(301) 496-3465

Position can begin July, 1991

Equal Opportunity/Affirmative Action Employer

We'll Help You BuildA New Lab

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Let the free Science product in-formation service put you in touchwith the vendors whose productsyou will need.

Simply write us a letter statingthe specifics about your proposedlab and the instruments andsupplies you need. We will do therest. Write to:SCIENCE MagazineNew Lab Service Department1515 BroadwayNew York, NY 10036

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MCIENCE II1304

POSITIONS OPEN

.

SCILENCEI, VOL. 250

POSITIONS OPEN

THE ROYAL SOCIETY

ROYAL SOCIETY UNIVERSITYRESEARCH FELLOWSHIPS

Applications are invited for about 30 Royal Society UniversityResearch Fellowships tenable in the first instance for five yearsfrom 1 October 1991 (or slightly later in the academic year 1991-92), with two possible further renewals for three and then two years.The Fellowships are available in any branch of science, includingagriculture, medicine, mathematics, engineering and technology.The primary criterion for selection will be scientific merit based onrecord so far and on future potential. Some account will also betaken of the facilities and intellectual environment being offered bythe prospective host department. Salaries will be on the nonclinicaluniversity scale, with London Allowance where appropriate. Annualresearch expenses (a sum of up to £10000 may be sought in 1991-92) will be available, together with return travel and a contribution tobaggage costs for successful applicants from overseas and theirfamilies.

Applicants should be Scientists normally with between 3 and 10years of post doctorial research experience. They must be BritishCitizens and propose to hold the fellowships in universities orpolytechnics in the United Kingdom. Those who already havesubstantive posts in these places will not normally be considered.Previously unsuccessful applicants are welcome to apply again ifstill eligible, but should make fresh applications and arrange forupdated referee's statements.

Application details are available (on written request only) from Mrs.U. M. A. Tokle, The Royal Society, 6 Carlton House Terrace,London, SW1Y 5AG (FAX: 071-930 2170). Closing date 15 Febru-ary 1991. Application forms will not be available after 1 Februaryand no application arriving after 4 p.m. on 15 February will beconsidered.

U .S. DEPARTMENT OF ENERGY

OSTGRADUATERESEARCH PROGRAMS

ToxicologyFossil EnergyHazardous WastesArtificial IntelligenceComputer Sciences

EngineeringPhysical SciencesEnvironmental SciencesLife SciencesRisk Analysis

* Research at national laboratories* Stipends $20,000 - $41,000 depending on degree,

program, research area* Recent graduate degree* U.S. citizens or PRAs eligible

Information and applications:

Postgraduate Research Programso Science/Engineering Education Division

Oak Ridge Associated Universities1AE\U P.O. Box 117

Oak Ridge, TN 37831-0117(615) 576-3190

POSITIONS OPEN

RESEARCH ASSOCIATE. For university in west-ern Oregon to conduct research: chemical synthesis andcharacterization of organic molecules as probes andreagents for biological and mcdical studies, synthesis andmodification of conducting polymers, development ofprocesses for chemical construction and fabrication ofmicroscale conducting wires fiom novel monomers andconducting polymers, and generation of submicron cir-cuits using electron beam lithography. Job requires aPh.D. cemisry and familiarity with organic synthesistechniques, HPLC, high ficld FT-NMR, FT-IR, UV,and MS techniques for characterization of new com-pounds, polymer synthesis and microlithographic tech-niques, and ChemDraw and Microsoft Word computerprograms. Forty hours per week, $18,492 per year. Musthave proof of lgal authority to work in the United States.Scnd rcsumc in duplicate to: Employment Division,JO# 5550055, 875 Union Street, N.E., Room 201,Salem, OR 97311.

RESEARCH ASSOCIATE. To conduct rescarch onrevcrsiblc immortalization of neural and muscl ccls,developing new approaches to the treatment ofmusculardystrophy and other degcncrative discases. Candidatesmust havc a B.S. in biochemistry with 3 years of researchezperience or M.S. The successful candidate must havcresearch experience in: (i) primary musde cell culture andneural ccll culturc; immortlization of neural and musclecells; (ii) antisense oligodeoxynucleotide constructionand manipulation; cxpression vector construcon forimmortalization; (iii) tumor suppressor gene cxpressionand regulation in neural and muscle clls; and (iv) cellanalysis by flow cytometry and the MIT method. Fortyhours per weck; $27,000 per year. Send this ad and yourresume in duplicate to: C. Wester, UCLA/Reed Ncu-rolog, 710 Westwood Plaza, Los Angeles, CA90024 1769. An Equal Opponunity Employer.

RESEARCH ASSOCIATE POSMTION. Availableto study (i) signal transduction mcchanisms involved inthe cardiac actions of EGF, (ii) transcriptional/transla-tional regulation of the ANF receptor/guanylatc cydasein rgnerating livers, and (iii) metabolic and growthmodulating actions of atrialnatriuretic factor. Applicantsmust possess an M.D. and/or Ph.D. degree in one of thebiomedical sciences with at least 2 years of training in thearea of biochemical pharmacology. The individual isezpected to analyze data, write manuscripts, compete forexramural grant support, and present seminars andjournal dubs reiated to his/her work. Annual salary:$23,004. Forward curnculum vitae and arrange for threektters ofrecommendation (by 31 December 1990) to bcsent to: Mrs. Edna Flynn, Tennessee Job Scrvice,1295 Poplar Avenue, Memphis, TN 38104 EqualOpportunity/Ajlrmative Action/Tide X/Section 504 Em-ployer. Minority candidates and women are especally encour-aged to apply.

RESEARCH ASSOCIATEApplications are invited for a nontenure-track faculty

position to study factors affecting proteolysis in bacteria.Specific points of intcrest include stabilization ofcukary-otic proteins synthesized in bacteria, enzymes responsiblefor protein breakdown, mutations that altcr proteimbreakdown, and changes in protein breakdown ted togrowth conditions. Requires Ph.D. plus laboratory e-ncnce in molecular biology and molecular cloning. An-nual starting salary: $27,804 plus full benefit package.

Interested candidates please forward your curriculumvitae and the names of three e nces to: Dr. LeeSimon, Waksmn Institte, Rutgers, The State Uni-versity ofNew Jersey, P.O. Box 759, Piscataway, NJ08855-0759. Sucesfil candidate to provide enpoymenteligUity verification-

Ajirtnative Action/Equal Opportunity Employer.

The Philadelphia Biomedical Research Institute offerspositions for SENIOR RESEARCH SCIENTISTSwho want to establish their own research lboratory tostudy cancer or AIDS. The institute docs not have iitialsalary, but will offer laboratory facilities and administa-tive assistance. The applicants should have their ownon-going grants, or be ready to submit research grantsfrom our institute. Collaboration with research groups inUniversity of Pennsylvania, Temple University, and oth-er schools in Philadelphia area is possible. Contact: Dr.S. T. Ohnishi, Ph.D., Director, 502 King of PrussiaRoad, Radnor, PA 19087. The Philadelphia BiomdicalResearch Insitute is a nonprofit institute and is an EqualOpportunity Employer.

INSTITUTE OF ECOSYSTEM STUDIESSOIL MICROBIAL ECOLOGIST

ASSISTANT OR ASSOCIATE SCIENTIST posi-tion available for ecologist with research interests in soilmicrobial ecology. Successful alicant will interact witha diverse group of terrcstial and aquatic ecologists withan ecosystem focus. Foundation grant available to sup-port a strong rcsearch program in soil microbial ecology.Ph.D. required; postdoctoral ezperience desirable.A letter of application, curriculum vitae, and names of

three references should be sent by 15 January 1991 to:

Dr. Gene E. Likens

Search C itte

Institute of Ecoystem StudiesThe New York Botanical Garden

Boz ABMilibrook, NY 12545

Equal Employm Opporunity.

Unique opportunity to participate in the expansion ofMcLaughlin Research Institutc, a small mammalian ge-netics center in Great Falls, Montana. Inunediate open-ings for ESTABLISHED INVESTIGATORS to workin a nonbureaucratic, interactive research environmentand to participate in the design of the new facility and inrecruitment and selection ofadditional scientists. Currentresearch prgrams are on the genencs ofsuscepibility tocancer and neurodegenerative diseases, but recruits willplay a major role in determining future research direc-tions. For more inforinaton, contact: George A. Carl-son, Scientific Director, McLaughlin Research Insti-tute, 1625 3rdAvnue North, Great Fas, MT 59401or any of the following members ofour Scientific Advis-ory Comuittee: Jcff Frelinger, Norm Reed, Lee Hood,Ncal Copeland, or Irv Wcissman.An Equal Opportunity/Affimative Action Employer.

ASSISTANT SCIEINTIST. Position in the SurgicalMctabolism and Nutrition Laboratories at the Univcrsityof Florida. Ph.D. degrce required with strong research

intcrest in molecular biology. Application deadline: 15Decenber 1990. Starting date: 1 January 1991. Salary:ncgotabk. Contact: WleyW. Souba, M.D, Box J-286,JHMHC, Univesity of Florida, Ganesvill, FL32610. Equal OpportunitylAflinnativeAcion Ensployer.

BIOLOGIST. Wc currendy havc a position availabkfor an cxperienced molecular biologist in our BasicRcsearch Division. You will conduct cperiments involv-ing doning, sequencng, PCR, gene ezpression, andregulation. Experience in mammalian ccll culture is pre-ferred; 2 to 5 ycars ofexperience as a molecular biologistis required.

Syntex offers outstanding research facilities in a beau-tiful campus-like setting. Our comprchensive benefitspackage includes an annual Bay Area cash bonus pro-gram, a day care facility, and an on-site health club. Forimmediate consideration, plase send your re'sume to:Syntex, Prolnssionl Sting Deptent SH, 3401Hillview Avenue, P.O. Box 10850, Pal Alto, CA94303. We are an Equal Opportunity Employer.

ASSISTANT STAFF SCIENTIST. Responsible forindependent resech in purification and recovery ofrecombinant proteins expressed in microbial and mam-malian cell hosts and design of separation processes forthe pilot manufacturing plant. Research techniques uti-lized indude laser light scattering and chromatgraphicseparation techniques, such as ion ecchange, affinity,metal cleating chromatography, size exclusion chroma-tograpy, and gel electrophoresis. Design responsibilitics

design of laser light scattering apparatus and ofseparation p for pilot plant. Requirements:Ph.D. in chemical enginring and 1 year of workexperence in scientific research.xpeperience must include(i) design and use of laser light scattring apparatus tostudy proteins, inclding computer analysis of data, and(ii) perfrmance of rescarch in proten measuremnttechnology including chromatographic separation tech-niques. Must have published at least three articles on

related topics in eed scientific joumals. Position

located in Seattle, Washington. Must have proofof lgalauthority to work in the United States. Working conditions:40 hours per weeck;8 a.m. to 5 p.m., Monday to Friday.Salary range: $32,000 to $34,000 per annum, DOE.Please sn by 31 Dmber 1990 to: Employ-ment Security De t, ES Division, Jo #

235516, Olympia WA 98504. Equal Opportunity Em-Plyr

Rhone Merieux, Inc., has openings for SCIEN-TISTS, ASSISTANT SCIENTISTS, and TECHNI-CLANS in research/development/manufacturing of vet-erinary vaccines and diagnostic products. Positionsrequire either B.S., M.S., Ph.D., D.V.M., or equivalenteducation/expenence. Industrial background in virologyand bacteriology higly beneficial.We offer competitive salary/benefits program with

opportunity for advancement. Please submit curriculumvitae, transcripts, and salary requirements in confidenceto: M. J. Holcomb, Rhone Merieux, Inc., 115 Trans-tech Drive, Athens, GA 30601.

MATERIALS SCIENTIST. For a university in south-western Ohio. Individual will plan, conduct, and superviseresearch on the morphology of rigid-rod polymerk mate-rials, molcular composites, carbon fibers, and nonlinearoptical polymers and establish relationship between miro-

and physical properties incuding compressive

strength, eectric conductivity, and nonlinear optical prop-erty. Will apply various morpholgical techniques includ-ing small and wide angle x-ray scattering and electronmicroscopy. Wi redesgn or modify the current tech-niques and use sy r sources as well as developnecessary computer programs. Will also study the micro-medunisms of deformation processes in rigid-rod poly-meric materials. Will supervise the research efforts ofoneresearch technician. Requires Ph.D. in matrials of poly-mer science. No experience required in above duties, butapplicants will qualify with a minimum of 2 years ofpostdoctoral expince in each of the following specificareas: (i) polymrk materials research; (ii) wide angle x-raydifactometer with pole figure device; (iii) small anglex-ray camera with double mirror focusing device andtwo-dimnsional position-sensitive detector system; (iv)transmission electron microscopy; (v) computer program-ming (Fortran lngua); (vi) mechanical testing istru-ments (Instron orMuli Testing System). Forty hours perweek, 7:45 a.m. to 4:30 p.m.; $42,000 per year. Must haveproof of lgal autdhty to work pennaendy in the UnitedStes. Send r6sum6 in duplicate (no calls) to: J. Davies,JO# 1266470, Ohio Bureau ofEmpoyment Srvices,P.O. Box 1618, Columbus, OH 43216.

COURSES AND TRAININGREACnON KINETICS SIMULATION COURSEUndrstnding Complcx Biological Systems by Com-

puter Simulation: hands-on tainiing using new PC soft-ware developed at Duke University by the National Bio-medical Simulatin Resource to simplify analysis ofbiochemical regulatory systems and pharmacokinetcs; In-trod y Course:18 to 22 March 1991; AdvancedCourse:14 to 16 May 1991. Brochure: Cook ColkgeOffice ofC inui P ional Educaion, RutrsUniversity, P.O. Box 231, Ncw Brunswkk, NJ 08903.Telphone: 908-932-9271; FAX-: 908-932-8726.

SITUATIONS WANTED

BIOCHEMIST, Ph.D. (1985). Experience in purifi-cation of protein, enzyme, cell culture, cDNA cloningand sequencing, antinuclear antibodies. Seeking resarch/industrial position. Box 134, SCIENCE.

MAKETPLACE

0sw.w a tor tne Kersn i eases, 7. toreach additional baie. No additional charges.

Research Genetics__

1306 SCIENCEI VOL. 250

POSITIONS OPEN POSITIONS OPEN

HOWARD HUGHES MEDICAL INSTITUTE

POSTDOCTORALRESEARCHFELLOWSHIPS FORPHYSICIANS

1991 Competition25 Fellowships will be awarded to physicians by the Howard Hughes Medical Institute for threeyears of training in fundamental biomedical research. Awards, based on an international competitioneach year, focus on research directed to an understanding of basic biological processes and diseasemechanisms. Fellowships may be held at any academic or research institution including but notlimited to Hughes laboratories.

* Fellowship Terms e Three years of support* Full-time fundamental research* $35,000-$50,000 annual stipend* $15,000 research allowance* $12,000 institutional allowance

* Eligibility . M.D., M.D./Ph.D., or D.O., with the M.D. or D.O. awarded no earlierthan 1982

* At the start of the fellowshipat least two years of postgraduate clinical training completedno more than two years of postdoctoral research training completed

* Applicants (and fellows) may not have faculty appointments* Fellows may not be enrolled in graduate degree programs* No citizenship requirements; U.S. citizens may study abroad, others

must study in the United States

* Schedule * Application deadline: March 1, 1991* Awards announced: September 1991* Fellowships start: January 1, 1992 - September 1, 1992

FOR 1991 PROGRAM ANNOUNCEMENTS AND APPLICATIONSHoward Hughes Medical InstituteOffice of Grants and Special ProgramsPostdoctoral Research Fellowships for PhysiciansDepartment NA916701 Rockledge DriveBethesda, MD 20817, United States of AmericaTelephone (301) 571-8412

The Howard Hughes Medical Institute, an Equal Opportunity Employer, welcomes applications from allqualified candidates and encourages women and members of minority groups to apply.

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