UAMS | Arkansas - Gurley Curriculum Vitae 2016 · 2017-07-25 · Research Center, Baton Rouge, LA....

CURRICULUM VITAE Bill J. Gurley, Ph.D. Professor of Pharmaceutical Sciences College of Pharmacy University of Arkansas for Medical Sciences 4301 West Markham, Slot 522-3 Little Rock, Arkansas 72205 Tel: 501/686-6279 E-mail: [email protected] PERSONAL INFORMATION Residence: 10 Christopher Cove Little Rock, Arkansas 72223 (501) 221-9440 Place of Birth: Memphis, Tennessee Birth date: December 31, 1959 Marital Status: Married, two children (Patrick and Rachel) EDUCATION Bachelor of Science Tennessee Technological University (Pre-Pharmacy/Chemistry) June 1980 Bachelor of Science University of Tennessee, Memphis (Pharmacy, with honors) June 1983 Doctor of Philosophy University of Tennessee, Memphis (Pharmaceutics) December 1989 Dissertation: "Influence of Hepatic Allograft Surgery on Cyclosporine Pharmacokinetics in the Canine" APPOINTMENTS Academic

Professor of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, February 2003 – present. Adjunct Professor, College of Arts and Sciences, Department of Biology, University of Arkansas at Little Rock, November 2001 – present.

Associate Professor of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, May 1995 – 2003

APPOINTMENTS (cont.)

Chairman (interim), Department of Pharmaceutics, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, October 1996 – October 1998

Assistant Professor of Pharmaceutics, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, July 1989 - 1994 Director, Clinical Pharmacokinetics Research Laboratory, University of Arkansas for Medical Sciences, Little Rock, Arkansas, July 1992 – present Graduate Teaching Assistant, College of Pharmacy, University of Tennessee, Memphis; Memphis, Tennessee, September 1984 – June 1989 Non-academic

Chief Science Officer, Balm Innovations, LLC., UAMS Bioventures incubator company. October 2005 – present. Advisory Board, American Botanical Council. October 2007 – present. Editorial Board, Clinical Pharmacology & Therapeutics. October 2009 — present. Chair, UAMS Institutional Animal Care and Use Committee. January 2010 — present. USP Expert Committee on Botanical Dietary Supplements. June 2010 — 2015. Editorial Board, Phytomedicine. January 2012 — present. USP Expert Committee on Non-botanical Dietary Supplements. June 2015 — present. USP Dietary Supplements Admission Evaluations Joint Standards Setting Subcommittee. April 2016 — present.

INSTRUCTION University of Arkansas for Medical Sciences, College of Pharmacy: 1989 to present

Instructor (2014-present) Pharmaceutics (PhSci 3414), a 4 credit hour didactic course. Instructor (2014-present) Pharmacology (PhSci 4134), a 4 credit hour didactic course. Instructor (2010-present) Pharmacology (PhSci 4124), a 4 credit hour didactic course. Instructor and Course Coordinator (2003-present) Drug Interactions (PhSci. 5122), a 2 credit hour didactic course.

INSTRUCTION (cont.)

Instructor and Course Coordinator (1991-present) Clinical Pharmacokinetics (PhSci. 4642), a 4 credit hour didactic course. Instructor and Course Coordinator (1994-present) Chromatographic Separations: Medical and Pharmaceutical Applications (PHSC. 5464), a 3 credit hour didactic graduate course.

Instructor (1993-present) Special Problems in Pharmaceutical Sciences (PHSC. 5262), a 3 credit hour didactic graduate course

Instructor (1994-present) Advanced Biopharmaceutics and Pharmacokinetics (PHSC. 517V), a 3 credit hour didactic graduate course. Instructor (1994-present) Pharmacokinetic Research Design and Data Analysis (PHSC. 5192), a 3 credit hour didactic graduate course.

Instructor (1994-present) Pharmaceutical Analysis (Biopharm. 3273), a 3 credit hour didactic course.

Instructor (1992-2000) Computer Applications in Pharmacokinetics and Biopharmaceutics, a 2 credit hour elective course.

Instructor and Course Coordinator (1992-2000) Pharmaceutical Calculations (Pharm. 3402), a 2 credit hour didactic course.

Instructor and Course Coordinator (1989-1990) Biopharmaceutics and Clinical Pharmacokinetics (Pharm. 4673), a 3 credit hour didactic course.

Instructor (1989-1991) Pharmaceutics II Lab: Parenteral Preparations (Pharm. 3433) 3 hours per week for a period of12 weeks.

University of Tennessee, Memphis: 1988

Instructor and Course Coordinator (1988) Basic Pharmacokinetics (Pharm. 416), a 3 credit hour didactic course.

AWARDS AND HONORS

2016—UAMS, Department of Pharmaceutical Sciences “Outstanding Professor”

Award. 2015—Selected to serve on the United States Pharmacopeia (USP) Expert

Committee on Non-botanical Dietary Supplements. 2012—Selected to serve on the Editorial Board for the journal Phytomedicine 2012—UAMS, Department of Pharmaceutical Sciences “Outstanding Professor”

Award.

AWARDS AND HONORS (cont.) 2010—Selected to serve on the United States Pharmacopeia (USP) Expert

Committee on Botanical Dietary Supplements. 2009—Selected to serve on the Editorial Board for the journal Clinical Pharmacology

& Therapeutics 2008—Selected to serve as an External Advisory Committee Member for the NIH-

sponsored Botanical Research Center at the Pennington Biomedical Research Center, Baton Rouge, LA.

2007—Selected to serve on the Advisory Board to the American Botanical Council 2004—UAMS, Department of Pharmaceutical Sciences “Most Outstanding Faculty

Award.” 2001—Elected to the Board of UAMS History of Medicine Associates.

2000—UAMS, Department of Pharmaceutical Sciences “Most Outstanding Faculty Award.”

1997—Lloyd R. Thompson Memorial Award for the "Most Outstanding Professor in the UAMS Department of Pharmaceutics." 1995—Lloyd R. Thompson Memorial Award for the "Most Outstanding Professor in the UAMS Department of Pharmaceutics." 1994—American Association of Colleges of Pharmacy New Investigator Award 1993—R. Clifton Brooks Medical Research Fellowship. 1992—Murphy Oil Corporation Medical Research Award. 1987—National Student Research Forum, University of Texas Medical Branch, Galveston, The Roche Laboratories' Award for Excellence of Research in Clinical Sciences (First Place). 1987—National Student Research Forum, University of Texas Medical Branch,

Galveston, The Gip A. Hudson Memorial Prize for the best presentation related to the liver and its diseases.

1987—University of Tennessee, Memphis, Sigma Xi Research Recognition Award

(First Place). 1986—University of Tennessee, Memphis, Student Government Association

Executive Council Meritorious Service Award. 1986—Sigma Xi, The Scientific Research Society 1983—University of Tennessee, Memphis, College of Pharmacy Merck

Pharmaceutical Undergraduate Research Award.

AWARDS AND HONORS (cont.) 1982—University of Tennessee, Memphis, Don L. Martinez/Hoffman La Roche

Undergraduate Pharmaceutical Research Award 1981—Rho Chi, Pharmacy Honor Society 1979—Phi Kappa Phi, National Honor Society

MEMBERSHIPS American Association of Pharmaceutical Scientists, 1986 – present American Association of Colleges of Pharmacy, 1991– present American Association for the Advancement of Science, 1990 – present American Society for Clinical Pharmacology and Therapeutics, 2002 – present JOURNALS REFEREED Pharmaceutical Research, 1996 – present International Journal of Pharmaceutical Compounding, 1998 – present Journal of Pharmaceutical Sciences, 1999 – present American Hospital Formulary Services (AHFS) Drug Information, 2000 – present American Journal of Health-Systems Pharmacy, 2001 – present Journal of Herbal Pharmacotherapy, 2001 – present AAPS PharmSci (electronic journal), 2001 – present Journal of Agricultural and Food Chemistry, 2001 – present Pharmacoepidemiology and Drug Safety, 2001 – present American Journal of Preventative Medicine, 2002 – present Clinical Pharmacology & Therapeutics, 2002 – present Drug Metabolism and Disposition, 2003 – present Canadian Journal of Physiology and Pharmacology, 2003 – present Pharmacogenetics, 2004 – present Mayo Clinic Proceedings, 2004 — present

JOURNALS REFEREED (cont.) Current Drug Metabolism, 2006 — present Planta Medica, 2006 — present Molecular Nutrition & Food Research, 2007 — present Biopharmaceutics & Drug Disposition, 2007 — present HerbalGram, 2007 — present Annals of Clinical Biochemistry, 2007 — present Journal of Pharmacy and Pharmacology, 2008 — present International Journal of Pharmaceutics, 2008 — present British Journal of Clinical Pharmacology, 2008— present Methods and Findings in Experimental and Clinical Pharmacology, 2008 — present Life Sciences, 2008 — present Clinica Chimica Acta, 2009 — present Drugs, 2009 — present Archives of Internal Medicine, 2010— present European Journal of Pharmaceutical Sciences, 2010— present Current Drug Discovery Technologies, 2010— present Expert Opinion on Drug Metabolism & Toxicology, 2010— present Phytomedicine, 2102 — present Clinical Therapeutics, 2012 — present Journal of Clinical Psychiatry, 2013 — present Clinical Pharmacokinetics, 2013 — present Current Neuropharmacology, 2015 — present British Medical Journal, 2015 — present

PUBLICATIONS (Scientific) 1. Buice RG, Sidhu P, Gurley BJ, and Hamilton C. Reversed-phase high performance

liquid chromatographic determination of methadone in human plasma. Research Communications in Substances of Abuse, 3: 97-108, 1982.

2. Buice RG, Sidhu P, Gurley BJ, Niell HB. Reversed-phase HPLC determination of

mitomycin-C in human serum. Therapeutic Drug Monitoring, 4: 293-296,1984. 3. Buice RG, Niell HB, Gurley BJ, and Sidhu P. Pharmacokinetics of mitomycin-C in

non-oat cell carcinoma of the lung. Cancer Chemotherapy and Pharmacology, 3:1-4,1984.

4. Buice RG, Veit BC, McAlpin SE, Gurley BJ, and Sidhu P. Effects of total body

irradiation followed by bone marrow transplantation on the disposition kinetics of mitomycin-C in the rat. Research Communications in Chemical Pathology and Pharmacology, 44: 401-410, 1984.

5. Buice RG, Veit BC, McAlpin SE, Gurley BJ, Sidhu P, and Thais A. Effects of total

body irradiation followed by bone marrow transplantation on the disposition kinetics of methotrexate in the rat. Research Communications in Chemical Pathology and Pharmacology, 47:123-132, 1985.

6. Gurley BJ, Buice RG, and Sidhu P. Reversed-phase high performance liquid

chromatographic determination of nifedipine in human plasma. Therapeutic Drug Monitoring, 7: 321-323,1985.

7. Buice RG, Gurley BJ, Stentz FB, Sidhu P, McClellan T, and Williams JW.

Cyclosporine disposition in the dog: Comparison of radioimmunoassay with high-performance liquid chromatographic assay and pharmacokinetics following intravenous administration. Transplantation , 40: 483-488, 1985.

8. Gurley BJ. Ozone: Pharmaceutical sterilant of the future? Journal of. Parenteral

Science and Technology., 39: 256-261,1985. 9. Buice RG, Gurley BJ, and Sidhu P. The plasma time-course of orally administered

cyclosporine in the dog. Research Communications in Chemical Pathology and Pharmacology, 50:143-146,1985.

10. Buice RG, Stentz TB, and Gurley BJ. Analytical methodologies for cyclosporine

pharmacokinetics. Journal of Liquid Chromatography,10: 421-438,1987. 11. Gurley BJ. Influence of Hepatic Allograft Surgery on Cyclosporine Pharmacokinetics

in the Canine, Doctoral Dissertation. University Microfilms Inc. Ann Arbor MI., No. 9033658, 1990.

12. Gurley BJ, VanVoorst SJ, Adamec T, Dean P, and Buice R. In situ hypothermic

asanguineous liver perfusion with whole blood reperfusion: A canine hepatic autotransplantation model. Transplantation Proceedings, 25:2969-2972,1993.

13. Olsen KM, Gurley BJ, Davis GA, and Christensen R. Stability of flumazenil with

selected drugs in 5% dextrose injection. American Journal of Hospital Pharmacy, 50:1907-1912,1993.

PUBLICATIONS (cont.) 14. Cone JB, Wallace BH, Gurley BJ, Olsen KM, Caldwell FT, and Bond PJ. The

pharmacokinetics of ibuprofen following burn injury. Journal of Burn Care and Rehabilitation, 14:666-669,1993.

15. Gurley BJ, Zermatten S, and Skelton D. Determination of antipyrine in human serum

by direct injection restricted access media liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis, 12: 1591-1595, 1994.

16. Olsen KM, Gurley BJ, Davis G.A., Ma FH, Archer S, and Ackerman BH. Comparison

of fluid volumes with whole bowel irrigation in a simulated ibuprofen overdose. Annals of Pharmacotherapy, 29: 246-250,1995.

17. Gurley BJ., Marx M., and Olsen K. Phenytoin free fraction determination: comparison

of an improved direct serum injection high performance liquid chromatographic method to ultrafiltration coupled with fluorescence polarization immunoassay. Journal of Chromatography B, 670: 358- 364,1995.

18. Gurley B.J. SPS determination of antipyrine in human serum. Regis RAM

Application Note #48, pp1-4, 1995. [RAM Notes is a peer-reviewed publication from Regis Technologies Inc., Morton Grove Illinois]

19. Gurley BJ, Barone G, Yamashita K, Polston S, Estes M, and Harden A. Extrahepatic

ischemia-reperfusion injury reduces hepatic oxidative drug metabolism as determined by serial antipyrine clearance. Pharmaceutical Research, 14: 67-72, 1997.

20. White LM, Gardner SF, Gurley BJ, Marx MA, Wang P, and Estes M.

Pharmacokinetics and cardiovascular effects of ma-huang (Ephedra sinica) in normotensive adults. Journal of Clinical Pharmacology 37: 116-122, 1997.

21. Gubbins P, Gurley BJ, and Bowman J. Rapid and sensitive high performance liquid

chromatographic method for the determination of itraconazole and its hydroxy-metabolite in human serum. Journal of Pharmaceutical and Biomedical Analysis 16: 1005-1012, 1998

22. Christiansen K, Gubbins P, Gurley BJ, and Bowman JL. Relative bioavailability of

itraconazole from an extemporaneouslly prepared suspension and from the marketed capsules. American Journal of Health-Systems Pharmacy 55: 261-265, 1998.

23. Nyamweya NN, Gurley BJ, Breen P, and Light KE. Pharmacokinetics of cocaine and

metabolites following intragastric administration to ten day old rat pups. Pharmaceutical Research 15: 488-491, 1998.

24. Gurley BJ, Gardner SF, White LM, and Wang P. Ephedrine pharmacokinetics

following the ingestion of Ephedra sinica (ma-huang) products. Therapeutic Drug Monitoring 20: 439-445, 1998.

25. Gurley BJ, Wang P, and Gardner SF. Ephedrine-type alkaloid content of nutritional

supplements containing Ephedra sinica (ma-huang) as determined by high performance liquid chromatography. Journal of Pharmaceutical Sciences 87:1547-1553, 1998.

PUBLICATIONS (cont.) 26. Penzak S, Gubbins P, Gurley BJ, Wang P, and Saccente M. Grapefruit juice

decreases the systemic availability of itraconazole capsules in healthy volunteers. Therapeutic Drug Monitoring 21:304-309, 1999.

27. Gurley BJ , Gardner SF, and Hubbard MA. Content versus label claims in ephedra-

containing dietary supplements. American Journal of Health-Systems Pharmacy 57:963-969, 2000.

28. Gurley BJ. Extract versus herb: Effect of formulation on the absorption rate of

botanical ephedrine from dietary supplements containing Ephedra (ma huang) Therapeutic Drug Monitoring 22:497, 2000.

29. Barone GW, Gurley BJ , Ketel BL, Lightfoot ML, Abul-Ezz SR. Drug interaction

between St. John’s Wort and cylosporine. Annals of Pharmacotherapy 34:1013-1016, 2000.

30. Abul-Ezz S, Barone GW, Gurley BJ, et al. St John's Wort Linked to Kidney Rejection.

Nephrology News & Issues 66:2000. 31. Barone GW, Ketel BL, Gurley BJ and King KE. The tolerability of newer

immunosuppressives in a patient with acute intermittent porphyria. Journal of Clinical Pharmacology 41:113-115, 2001.

32. Barone GW, Gurley BJ, Ketel BL, Lightfoot ML, and Abul-Ezz. Comment: drug-herb

interaction. Annals of Pharmacotherapy 35:124-125, 2001. 33. Barone GW, Gurley BJ, Ketel BL, and Abul-Ezz SR. Herbal dietary supplements: a

source for drug interactions in transplant recipients. Transplantation 71:239-241, 2001.

34. Kommuru TR, Gurley B, Khan MA, and Reddy IK. Self-emulsifying drug delivery

systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. International Journal of Pharmaceutics 212:233-246, 2001.

35. Turton-Weeks SM, Barone GW, Gurley BJ, Ketel BL, Lightfoot ML, and Abul-Ezz SR.

St. John's Wort: A hidden risk for transplant patients. Progress in Transplantation 11:116-120, 2001.

36. Penzak SR, Jann MW, Cold JA, Hon YY, Desai HD, and Gurley BJ. Seville (sour)

orange juice: synephrine content and cardiovascular effects in normotensive adults. Journal of Clinical Pharmacology 41:1-5, 2001.

37. Turton-Weeks SM, Barone GW, Gurley BJ, Ketel B, Lightfoot ML, Abul-Ezz SR, and

Anderson KE. The pretransplant evaluation of a patient with acute intermittent porphyria. Progress in Transplantation 11:214-216, 2001.

38. Zaghloul A, Gurley B, Kahn M, Bhagavan H, Chopra R, and Reddy I. Bioavailability

assessment of oral coenzyme Q10 formulations in dogs. Drug Development and Industrial Pharmacy 28:1195-1200, 2002.

PUBLICATIONS (cont.) 39. Gurley BJ, Gardner SF, Hubbard M, Gentry W, Williams D, Ang C, and Cui YY.

Cytochrome P-450 phenotypic ratios for predicting herb-drug interactions in humans. Clinical Pharmacology & Therapeutics 72: 276-287, 2002.

40. Cui YY, Gurley B, Ang CYW, Leakey J. Determination of hyperforin in human plasma

using solid-phase extraction and high-performance liquid chromatography with ultraviolet detection. Journal of Chromatography B 780: 129-135, 2002

41. Gubbins PO, Melchert RB, Gurley BJ, McConnell SA, Franks A. Effect of interleukin-

6 on the hepatic metabolism of itraconazole and its metabolite hydroxyitraconazole using primary human hepatocytes. Pharmacology 2003; 67:195-201.

42. Hendrickson HP, Gurley BJ, Wessinger WD. Determination of dextromethorphan

and its metabolites in rat serum by liquid-liquid extraction and liquid chromatography with fluorescence detection. Journal of Chromatography B 2003;788:261-268.

43. McCabe BJ, Gurley BJ. Transdermal selegiline and dietary tyramine: is there a

problem? Journal of the American Dietetic Association. 2003; 103 (Suppl. 9) 39-40.

44. Gardner SF, Franks AM, Gurley BJ, Haller CA, Singh Bk, Mehta JL. Effect of a multi-

component, ephedra-containing dietary supplement (Metabolife 356®) on holter monitoring and hemostatic parameters in healthy volunteers. American Journal of Cardiology. 2003; 91:1510-1513.

45. Barone GW, Gurley BJ, Abul-Ezz S, Gokden N. Sirolimus-induced thrombotic

microangiopathy in a renal transplant recipient. American Journal of Kidney Diseases. 2003; 42: 1-5.

46. Gubbins PO, McConnell SA, Gurley BJ, Fincher TK, Franks AM, Williams DK,

Penzak, Saccente M. Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers. Pharmacotherapy 2004; 24: 460-467.

47. Luer MS, Neill KK, Gurley BJ, Shannon ML, Killian AD, Rodvold KA. Fluctuations in

vancomycin CNS tissue concentrations following intermittent and continuous infusions in the rat. Neurological Research 2004; 26:312-315.

48. Gurley BJ, Gardner SF, Hubbard MA, Williams K, Gentry WB, Carrier J, Edwards D,

Khan I, Shah A. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clinical Pharmacology & Therapeutics 2004;76:428-440.

49. Kroll DJ,…Gurley Bill J…et al. American Society of Health-System Pharmacists

statement on the use of dietary supplements. American Journal of Health-System Pharmacy. 2004;61:1707-1711

50. Gurley BJ, Gardner SF, Hubbard MA, Gentry WB, Williams DK, Khan I, Shah A. In

vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes. Clinical Pharmacology & Therapeutics 2005;77:415-426.

PUBLICATIONS (cont.) 51. Gurley BJ, Gardner SF, Hubbard MA, Gentry WB, Williams DK, Cui Y-Y, Ang CYW.

Clinical Assessment of botanical supplementation on cytochrome P450 phenotypes in the elderly: St. John’s wort, garlic oil, Panax ginseng, and Ginkgo biloba. Drugs & Aging 2005;22:525-539. [PMC1858666]

52. Grippo AA, Hamilton B, Hannigan R, Gurley BJ. Metal content of ephedra-containing

dietary supplements and other select botanicals. American Journal of Health-Systems Pharmacy 2006;63:635-644.

53. Gurley BJ, Barone GW, Williams DK, Carrier J, Breen P, Yates CR, Song P, Hubbard

MA, Tong Y, Cheboyina S. Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans. Drug Metabolism & Disposition 2006;34:69-74. [PMC1868501]

54. Gurley BJ, Hubbard MA, Williams DK, Thaden J, Tong Y, Gentry WB, Breen P,

Carrier DJ, Cheboyina S. Assessing the clinical significance of botanical supplementation on human cytochrome P450 activity: Comparison of milk thistle and black cohosh to rifampin and clarithromycin. The Journal of Clinical Pharmacology 2006;46:201-213. [PMC1865122]

55. Gurley BJ, Swain A, Barone GW, Williams DK, Breen P, Yates CR, Hubbard MA,

Tong Y, Cheboyina S. Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans. Drug Metabolism & Disposition 2007;35:240-245. [PMC1865121]

56. Grippo AA, Capps K, Rougeau B, Gurley BJ. Analysis of flavonoids in botanical and

ephedra-containing dietary supplements. Annals of Pharmacotherapy 2007; 41:1375-1382.

57. Gurley BJ, Swain A, Hubbard MA, Hartsfield F, Williams DK, Thaden J, Gentry WB,

Tong Y. Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo. Clinical Pharmacology & Therapeutics, 2008; 83:61-69.

58. Gubbins PO, McConnell SA, Gurley BJ, Penzak SR, Williams DK, Franks AM,

Saccente M. Examining sex-related differences in enteric itraconazole metabolism with grapefruit juice. European Journal of Clinical Pharmacology, 2008; 64:293-301.

59. Gurley BJ, Swain A, Williams DK, Barone G, Battu S. Gauging the clinical

significance of P-glycoprotein-mediated herb-drug interactions: Comparative effects of St. John’s wort, echinacea, clarithromycin and rifampin on digoxin pharmacokinetics. Molecular Nutrition & Food Research, 2008; 52:772-779. [PMC2562898]

60. Gurley BJ, Swain A, Hubbard MA, Williams DK, Barone G, Hartsfield F, Tong Y,

Carrier DJ., Cheboyina S, Battu SK. Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: Effects of milk thistle, goldenseal, black cohosh, kava kava, St. John’s wort and echinacea. Molecular Nutrition & Food Research, 2008;52:755-763. [PMC2562884]

PUBLICATIONS (cont.) 61. Gupta P, Gurley BJ, Hubbard MA, Hendrickson H. Validation of a liquid

chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum. Journal of Pharmaceutical & Biomedical Analysis, 2009;49:1021-1026.

62. Gurley BJ. Clinical pharmacology and dietary supplements: an evolving relationship.

Clinical Pharmacology & Therapeutics, 2010;87:235-238. 63. Gurley BJ. Response to ‘Dietary supplements and the risk of Wernicke’s

encephalopathy.’ Clinical Pharmacology & Therapeutics, 2010;88:164-165. 64. Glisson JK, Minor DS, Walker LA, Gurley BJ. Dietary supplements: safety issues

and quality control. Archives of Internal Medicine, 2011;171:476. 65. Gurley BJ. Emerging technologies for improving phytochemical bioavailability:

benefits and risks. Clinical Pharmacology & Therapeutics, 2011;89:915-919. 66. Gurley BJ. Cranberries as antibiotics? Archives of Internal Medicine,

2011;171:1279-1280. 67. Gurley BJ. Pharmacokinetic herb-drug interactions (Part 1): origins, mechanisms,

and the impact of botanical dietary supplements. Planta Medica, 2012;78:1478-1489.

68. Gurley BJ, Fifer KE, Gardner Z. Pharmacokinetic herb-drug interactions (Part 2): drug

interactions involving popular botanical dietary supplements and their clinical relevance. Planta Medica, 2012;78:1490-1514.

69. Brown CE, Trauth SE, Grippo RS, Gurley BJ, Grippo AA. Combined effects of

ephedrine-containing dietary supplements, caffeine, and nicotine on morphology and ultrastructure of rat hearts. Journal of Caffeine Research, 2012;2:123-132.

70. Foster L, Allan MC, Khan A, Moore P, Williams DK, Hubbard M, Dixon L, Gurley BJ.

Multiple dosing of Ephedra-free dietary supplements: hemodynamic, electrocardiographic, and bacterial contamination effects. Clinical Pharmacology & Therapeutics, 2013;93:267-274.

71. Gurley, B. Dietary Supplement. Encyclopedia Britannica Online. Encyclopedia

Britannica Inc., 2014. Web. August 20, 2014. (http://www.britannica.com/EBchecked /topic /162791/dietary-supplement/%20supplement.)

72. Gurley BJ, Steelman S, Thomas S. Multi-ingredient, caffeine-containing dietary

supplements: history, safety, and efficacy. Clinical Therapeutics. 2015;37:275-301. 73. Gupta PK, Barone G, Gurley BJ, Fifer K, Hendrickson HP. Hydrastine

pharmacokinetics and metabolism after oral administration of goldenseal (Hydrastis canadensis) to humans. Drug Metabolism & Disposition. 2015;43:534-552.

74. Wang X, Zhu H-J, Munoz J, Gurley BJ, Markowitz JS. An ex vivo approach to

botanical-drug interactions: A proof of concept study. Journal of Ethnopharmacology. 2015;163:149-156.

PUBLICATIONS (cont.) 75. Hammond D, Thano E, Bohnenberger K, McAllister M, Wannenburg T, Hsu S, Gurley

B, Kim R. Ventricular tachycardia precipitated by the use of diet supplement Hydroxycut Gummies™. Hospital Pharmacy. 2015;50:615-618.

76. Fasinu PS, Gurley BJ, Walker LA. Clinically relevant pharmacokinetic herb-drug

interactions in antiretroviral therapy. Current Drug Metabolism. 2016;17:52-64. 77. Roe AL, Paine MF, Gurley BJ, Brouwer K, Jordan S, Griffiths J. Assessing natural

product-drug interactions: an end-to-end safety framework. Regulatory Toxicology & Pharmacology. 2016;76:1-6.

78. Chen SM, Atchley DH, Murphy MA, Gurley BJ, Kamdem LK. Impact of UGT2B17

gene deletion on the pharmacokinetics of 17-hydroexemestane in healthy volunteers. Journal of Clinical Pharmacology. 2016;56:875-884.

79. Oketch HA, Giancaspro GI, Gurley BJ, Roe AL, Griffiths JC. Importance of quality

specifications in safety assessments of amino acids—the cases of L-tryptophan and L-citrulline. Journal of Nutrition. 2016;146(Suppl):2643S-2651S.

80. Gurley BJ, Markowitz JS, Williams DK, Barone GW. Practical considerations when

designing and conducting clinical herb-drug interaction studies. International Journal of Pharmacokinetics. (in press, 2016).

PUBLICATION ACKNOWLEDGEMENTS 1. Nicotine absorption after pulmonary instillation. Journal of Pharmaceutical Sciences 81:1055, 1992. 2. The effect of ephedrine prodrugs on locomotor activity in rats. General

Pharmacology 27: 109-111, 1996. 3. Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement

use. Clinical Pharmacology & Therapeutics 2002; 71:421-432. 4. Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements.

Journal of Analytical Toxicology 2004; 28:145-151. 5. Assessing potential herb-drug interactions in the use of herbal dietary supplements:

need for a common framework approach. HerbalGram 2015; 107:40-43.

ABSTRACTS 1. Buice RG, Sidhu P, Gurley BJ, Hamilton C. HPLC determination of estramustine

phosphate metabolites in human serum. 33rd National Meeting of the Academy of Pharmaceutical Sciences, San Diego, California, November 5, 1982.

2. Buice RG, Niell HB, Gurley BJ, Sidhu P. Pharmacokinetics of intravenously

administered mitomycin-C in non-oat cell carcinoma of the lung. 74th Annual Meeting of the American Association for Cancer Research, San Diego, California, May 25, 1983.

3. Buice RG, Veit BC, Gurley BJ, Sidhu P. Effects of total body irradiation on the pharmacokinetics of methotrexate in the rat. 35th National Meeting of the Academy of Pharmaceutical Sciences, Miami, Florida, November 14, 1983.

4. Gurley BJ, Buice RG. Cyclosporine disposition in the dog: Comparison of RIA with

HPLC analytical methodology and pharmacokinetics following intravenous administration. 17th Annual Pharmaceutics Graduate Research Meeting, University of Kentucky, Lexington, Kentucky, June 20, 1985.

5. Buice RG, Gurley BJ, VanVoorst S. Effects of hepatic allograft surgery on cyclosporine disposition in the dog. 1st National Meeting of the American Association of Pharmaceutical Scientists, Washington, D.C., November 5, 1986.

6. Gurley BJ, Buice RG, Van Voorst S. Cyclosporine pharmacokinetics following canine

orthotopic hepatic allografts. 28th Annual National Student Research Forum, University of Texas Medical Branch, Galveston, Texas, April 22, 1987.

7. Olsen KM, Ma FH, Gurley BJ, Archer S, Ackerman BH. Comparison of fluid volumes

with whole bowel irrigation in a simulated overdose. Pharmacotherapy 1990; 10:256.

8. Gurley BJ, Buice RG, Van Voorst S. Influence of hepatic allograft surgery on

cyclosporine pharmacokinetics in the canine. Pharmaceutical Research 1990; 7 (suppl.): 222.

9. Olsen KM, Haas FD, Pablo CS, Ackerman BH, Gurley BJ, Brian E. Effect of liquid H2 antagonists on gastric volume and pH during anesthesia. Winter Practice and Research Forum, American College of Clinical Pharmacy, Fort Lauderdale, Florida, February 10, 1991.

10. Davis GA, Gurley BJ, Olsen KM, Monaghan M. Stability of flumazenil in the

presence of medications given by continuous infusion. American Society of Hospital Pharmacists, Orlando, Florida, December 9, 1992.

11. Cone JB, Wallace BH, Caldwell FT, Gurley BJ, Olsen KM. Burn injury alters the

pharmacokinetics of enteral ibuprofen. American Burn Association, Cincinnati, OH, March 25, 1993.

12. Gurley BJ, Zermatten S. Rapid and sensitive determination of antipyrine in human serum via restricted access media HPLC. Pharmaceutical Research 1994; 11 (suppl.): 24.

ABSTRACTS (cont.) 13. Gurley BJ, Marx M, Olsen KM. Comparison of ultrafiltration and direct injection

chromatography in determining phenytoin free fraction. Pharmaceutical Research 1994; 11 (suppl.): 24.

14. Gubbins PO, Gurley BJ, Arnold E, Tricot G, Vesole D, Bradsher RW, McDonnell R,

Zermatten S. A study to determine the pharmacokinetics of itraconazole and its metabolite, hydroxyitraconazole in allogeneic bone marrow transplant recipients. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California, September 17-20, 1995.

15. Harden A, Gurley BJ. Effect of renal and intestinal ischemia-reperfusion injury on

antipyrine free fraction. Second Annual McNair Scholars Research Symposium, University of Arkansas at Little Rock, Little Rock, AR, September 26, 1995.

16. Pitcock CD, Gurley BJ. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon in the Trans-Mississippi Theatre. American Osler Society, San Francisco, California , April 26, 1996.

17. White LM, Gardner SF, Gurley BJ, and Marx MA. Pharmacodynamics and pharmacokinetics of ma-huang (Ephedra) in normotensive subjects. Eleventh Annual Scientific Meeting of The American Society of Hypertension, New York, New York, May15- 18, 1996.

18. Marx MA, Gurley BJ, Plumlee H, and Golper TA. Iohexol clearance during

hemodialysis. Pharmacotherapy 1996; 16: 504. 19. Gurley BJ, Barone G, Polston S, Estes M and Yamashita K. Extrahepatic ischemia-

reperfusion injury alters hepatic oxidative drug metabolism. Pharmaceutical Research, 1996; 13 (suppl.): 431.

20. Gubbins PO, Gurley BJ, and Bowman J. Rapid and sensitive HPLC determination of

itraconazole (ITZ) and its hydroxy-metabolite (OH-ITZ) in human serum. Pharmaceutical Research, 1996; 13 (suppl.): 38.

21. Walker RB, Dholakia V. , Reed JR, Love LB, Ewing D, Bakhtiar R., and Gurley BJ.

Binding studies of an ephedrine prodrug with cyclodextrin analogs. Pharmaceutical Research, 1996; 13 (suppl.): 151.

22. Marx MA, Gurley BJ, Tattersall J., and Golper TA. Post-hemodialysis iohexol

rebound necessitates prolonged sampling strategy for use as dialysis quantitation. J. Am. Soc. Nephrol. 1996; 7 (9): 1520-1521

23. Christensen KJ, Gubbins PO, Gurley BJ and Bowman JL. Bioavailability of an

extemporaneous preparation of itraconazole. 31st American Society of Health System Pharmacists Midyear Clinical Meeting, New Orleans, Louisiana, December 8-12, 1996.

24. Watterson K, Gubbins PO and Gurley BJ. A pharmacokinetic (PK) study of itraconazole and its metabolite, hydroxyitraconazole (OHITZ), in allogeneic bone marrow transplant (BMT) recipients. Arkansas Cancer Research Center Partners in Research, Student Scientific Symposium, Little Rock, Arkansas, July 30, 1996.

ABSTRACTS (cont.) 25. Leveritt S, McIntyre W, and Gurley BJ. Do standardized dosage regimens of

ganciclovir provide adequate target concentrations to eliminate thymidine kinase transduced donor lymphocytes? Arkansas Cancer Research Center Partners in Research, Student Scientific Symposium, Little Rock, Arkansas, July 30, 1996.

26. White L., Gardner S., and Gurley BJ. Pharmacokinetics of ephedrine in three commercially available herbal (ma-huang) products. Spring Practice and Research Forum of the American College of Clinical Pharmacy, Panama City, Florida, April 6-9, 1997.

27. Gurley BJ, Gardner S., White L., and Wang P. Pharmacokinetics of ephedrine

following the ingestion of commercially available preparations of Ephedra sinica (ma-huang). Pharmaceutical Research, 1997; 14 (suppl.): S-519.

28. Gurley BJ, Gardner S., and Wang P. Ephedrine alkaloid content of five commerically

available herbal products containing Ephedra sinica (ma-huang). Pharmaceutical Research, 1997; 14 (suppl.): S-82.

29. McIntyre WJ, Gurley BJ, Munchi N, McClelland A, Estes M, and Leveritt S. Do

standardized regimens of ganciclovir provide adequate target concentrations to eliminate thymidine kinase transduced donor lymphocytes? Pharmacotherapy, 1997; 17 (5): 1131.

30. Compadre CM, Grady AR, and Gurley BJ. Introduction to patient monitoring:

example of integrated instruction. American Association of Colleges of Pharmacy Annual Meeting 1997; 95 (July):94.

31. Gurley BJ, Wang P, and Gardner SF. Ephedrine-type alkaloid content of nutritional

supplements containing Ephedra sinica (ma-huang). AAPS Southern Regional Discussion Group, Oxford, MS, May 28-29, 1998.

32. Luer MS, Shannon M, and Gurley BJ. Anticonvulsant activity of system-L inhibition. AAPS Southern Regional Discussion Group, Oxford, MS, May 28-29, 1998.

33. Penzak S, Gubbins PO, Gurley BJ, Wang P, and Saccente M. Effect of grapefruit juice on the systemic availability of itraconazole (ITZ) capsules. AAPS Southern Regional Discussion Group, Oxford, MS, May 28-29, 1998.

34. Penzak S, Gubbins PO, Gurley BJ, Wang P, and Saccente M. Effect of grapefruit

juice on the systemic availability of itraconazole capsules. 38th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA, September 24-27, 1998.

35. Gubbins PO, Gurley BJ, Fifer EK, Lay JO, and F. Caldwell. A lesson in HPLC column efficiency: characterization of the hydroxy-metabolites of itraconazole by HPLC, LC/MS, and NMR. PharmSci Supplement, 1998; 1: S-501.

ABSTRACTS (cont.)

36. Watterson KS, Gubbins PO, Gurley BJ, and Fifer EK. Characterization of the

hydroxy-metabolites of itraconazole by HPLC, LC/MS, and NMR. Proceedings of the Fifth Annual Undergraduate Research Conference. (Henderson State University)137-141, 1998

37. Luer MS, Gurley BJ, and Shannon ML. Anticonvulsant activity of system-L inhibition. Epilepsia ,1998; 39 (supplement 6) : 40.

38. Luer MS, Shannon ML, and Gurley BJ. Competitive inhibition of gabapentin brain uptake. Second Annual AAPS Southern Regional Discussion Group, Monroe, LA May 20-21, 1999.

39. Luer MS, Neill K, Shannon ML, and Gurley BJ. Acute phase response and blood-brain barrier P-glycoprotein function: Preliminary report. Second Annual AAPS Sourthern Regional Discussion Group, Monroe, LA May 20-21, 1999.

40. Gurley BJ and Wang P. “Caveat emptor:” ephedrine alkaloid content of herbal

dietary supplements containing Ephedra sinica (ma-huang). Second Annual AAPS Southern Regional Discussion Group, Monroe, LA, May 20-21, 1999.

41. Gurley BJ and Wang P. “Caveat emptor:” ephedrine alkaloid content of herbal

dietary supplements containing Ephedra sinica (ma-huang). American Association of Pharmaceutical Scientists (14th Annual Meeting), New Orleans, LA, November 14-18, 1999.

42. McConnell SA, Penzak SR, Fincher TK, Gurley BJ, Franks A, Saccente M, and

Gubbins PO. Sex-related differences in oral clearance observed for itraconazole when itraconazole oral solution is administered with water but not grapefruit juice. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy. Toronto, Canada, September 18, 2000.

43. Abul-Ezz SR, Barone GW, Gurley BJ, Barri YM, and Ketel BL. Effect of herbal

supplements on cyclosporine blood levels and associated acute rejection. The American Society of Nephrology (33rd Annual Scientific Meeting). Toronto, Canada, October 13, 2000.

44. Barone GW, Ketel BL, Gurley BJ, Anderson KE, Weeks SM, and Abul-Ezz SR.

Renal transplantation and acute intermittent porphyria. The American Society of Nephrology (33rd Annual Scientific Meeting). Toronto, Canada, October 13, 2000.

45. Gurley BJ, and Barone GW. Herb-drug interaction involving St. John’s wort and

cyclosporine. American Association of Pharmaceutical Scientists (15th Annual Meeting), Indianapolis, IN, October 29-November 2, 2000.

46. Gurley BJ, Gardner SF, and Hubbard MA. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. American Association of Pharmaceutical Scientists (15th Annual Meeting), Indianapolis, IN, October 29-November 2, 2000.

ABSTRACTS (cont.)

47. Kommuru TR, Gurley B, Khan MA, and Reddy IK. Formulation development and

bioavailability evaluation of self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10 American Association of Pharmaceutical Scientists (15th Annual Meeting), Indianapolis, IN, October 29-November 2, 2000.

48. Gubbins PO, Melchert RB, McConnell SA, Franks AH, Penzak SR, Gurley BJ. The

effect of interleukin-6 on the hepatic metabolism of itraconazole and its metabolite hydroxyitraconazole [Abstract 208]. Pharmacotherapy 2000

49. McConnell SA, Penzak SR, Fincher TK, Gurley BJ, Franks AH, Saccente M, Gubbins

PO. Sex-related differences in oral clearance observed for itraconazole when oral solution is administered with water and grapefruit Juice. [Abstract 862] 40th Interscience Conference of Antimicrobial Agents and Chemotherapy, September 17-20, 2000, Toronto, Canada.

50. Turton-Weeks SM, Barone GW, Gurley BJ, et al. The pretransplant evaluation of a

patient with acute intermittent porhyria. National Association of Transplant Coordinators, Orlando, FL August 6-8, 2000.

51. Turton-Weeks SM, Barone GW, Gurley BJ, et al. Herbal supplements: A hidden risk.

National Association of Transplant Coordinators, Orlando, FL August 6-8, 2000. (Awarded the Top Clinical Study)

52. Abul-Ezz S, Barone GW, Gurley BJ, et al. Effect of herbal supplements on

cyclosporine blood levels and associated acute rejection. The 33rd Annual Scientific Meeting of the American Society of Nephrology, Toronto, Ontario, Canada October 13, 2000.

53. Barone GW, Gurley B, Ketel B, et al. Renal transplantation and acute intermittent porphyria. The 33rd Annual Scientific Meeting of the American Society of Nephrology, Toronto, Ontario, Canada October 13, 2000.

54. Gurley B, Ali S. Toxicity of multi-component ephedra-containing dietary supplements.

American Association of Pharmaceutical Scientists (16th Annual Meeting), Denver, CO, October 21-25, 2001.

55. Zaghloul A, Gurley B, Kahn M, Bhagavan H, Chopra R, Reddy I. Bioavailability

assessment of oral coenzyme Q10 formulations in dogs. American Association of Pharmaceutical Scientists (16th Annual Meeting), Denver, CO, October 21-25, 2001.

56. Penzak SR, Jann MW, Cold JA, Hon YY, Desai HD, Gurley BJ. Seville orange juice:

synephrine content and effect on blood pressure in healthy subjects. American Association of Clinical Pharmacology, Tampa, FL, October 21-24, 2001.

57. Neill K, Luer M, Shannon ML, Gurley BJ. Age-related changes in blood-brain-barrier

P-glycoprotein function. Pharmacotherapy. 21:1287, 2001.

58. Gurley B , Ali S, Melchert R, McNew B, Lamps L. Toxicity of multi-component ephedra-containing dietary supplements. PharmForum 2002 (Southern Regional Discussion Group of AAPS, Little Rock, AR. May 31, 2002.

ABSTRACTS (cont.)

59. Luer MS, Neill KK, Shannon ML, Gurley BJ. Blood-Brain Barrier P-glycoprotein

Function is Reduced in Aged Rats. FASEB Journal 2002;16(5):A940. 60. Gentry WB, Gardner SF, Gurley BJ. St. John’s wort induces CYP2E1 in humans.

Anesthesiology 2002; 96:A441 61. Capps K, Grippo A, Gurley BJ. Bioflavonoids in herbal supplements. Arkansas

Biosciences Initiative, Little Rock, AR October 23, 2002.

62. Franks AM, Gardner SF, Gurley BJ, Singh BK, Mehta JL. Effect of a combination ephedra-containing supplement on cardiac rhythm. [Abstract 231]. American College of Clinical Pharmacology Spring Practice and Research Forum, Palm Springs, CA., April 29, 2003.

63. Hubbard MA, Gurley B, Gardner SF, Gentry WB, Williams DK, Carrier J. Clinical assessment of citrus aurantium, milk thistle, saw palmetto, and Echinacea on cytochrome P450 phenotypes. AAPS-Southern Regional Discussion Group meeting, Little Rock, AR, May 30, 2003.

64. McCabe BJ, Gurley BJ. Transdermal selegiline and dietary tyramine: is there a

problem? Journal of the American Dietetic Association. 2003; 103 (Suppl. 1) A25.

65. Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry B, Carrier J, Edwards D, Khan I. Assessment of botanical supplementation on human cytochrome P450 phenotype: citrus aurantium, Echinacea, milk thistle, saw palmetto. Clinical Pharmacology & Therapeutics. 2004; 75:P35.

66. Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry B. Effect of botanical

supplementation on cytochrome P450 phenotypes in the elderly. Clinical Pharmacology & Therapeutics. 2005; 77:P16

67. Gurley BJ, Gardner SF, Williams DK, Gentry WB, Hubbard MA, Khan IA, Shah A.

Effect of goldenseal, black cohosh, kava kava, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes. Clinical Pharmacology & Therapeutics. 2005; 77:P36.

68. Gurley BJ, Hubbard MA, Barone G, Tong Y, Williams DK, Carrier J, Khan IA.

Assessment of milk thistle and black cohosh supplementation on digoxin pharmacokinetics. Clinical Pharmacology & Therapeutics. 2005; 77:P49.

69. Gurley BJ, Gardner SF, Williams DK, Grippo A. Hemodynamic and electrocardiographic effects of an “Ephedra-free” dietary supplement (Metabolife Ultra™). Clinical Pharmacology & Therapeutics. 2006; 79(2):P2.

70. Pitcock CD, Gurley BJ. A young doctor’s military casebook, 1860-1865. 40th International Congress on the History of Medicine. Budapest, Hungary, August 26-30, 2006 (pg 87).

ABSTRACTS (cont.)

71. Bryant L, Gurley B, Allan C, Harris M, Hakkak R., Hemodynamic and

electrocardiographic effects of ephedra-free dietary supplements. Society of Experimental Biology, Washington, DC, April 28-May 2, 2007 (FASEB Journal. 2007;21:A1087).

72. Pitcock CD, Gurley BJ. A young doctor’s military casebook, 1860-1865. 37th Annual

Meeting of the American Osler Society, Montreal, Quebec, April 30-May 3, 2007 (pg. 32).

73. Gurley BJ, Bryant L, Allan C, Williams DK. Does “Ephedra-free mean trouble-free”? Clinical Pharmacology & Therapeutics, 2008; 83 (Suppl 1):S44.

74. Compadre C, Wang K, Darsey J, Melchert RB, Arnason JT, Gurley B. Development of predictive models of the inhibition of CYP3A4 by plant components. American Chemical Society, Southwest Regional Meeting, Little Rock, AR, October 2, 2008.

75. Gupta P, Hubbard M, Gurley BJ, Hendrickson H. Validation of a liquid

chromatography-tandem mass spectrometric assay for the determination of hydrastine and berberine in human serum. The AAPS Journal, 2008; 10 (Suppl. 2): abstract #2909.

76. Gupta PK, Barone G, Gurley BJ, Hendrickson HP. Clinical pharmacokinetics and

metabolism of berberine and hydrastine following an oral dose of goldenseal supplement. The AAPS Journal, 2009; 11 (Suppl. 2): abstract #3976.

77. Lahti TK, Gurley BJ, Hendrickson HP. Dissolution of hydrastine and berberine from

six commercial sources of goldenseal supplement. The AAPS Journal, 2009; 11 (Suppl. 2): abstract #4034.

78. Gurley BJ. Dosage form performance: An overlooked determinant of phytochemical

efficacy and safety. Planta Medica, 2010; 76, 504 (abstract #8). 79. Gupta PK, Gurley BJ, Barone G, Hendrickson HP. Clinical pharmacokinetics and

metabolism of berberine and hydrastine following an oral dose of goldenseal supplement. Planta Medica, 2010; 76, 546 (abstract #P110).

80. Khan AA, Tallent S, Akiyama T, Gurley B, Summage-West C. Rapid isolation and

indentification of toxin producing Bacillus cereus from dietary supplements. Food Program Science and Research Conference, Food and Drug Administration, Washington, DC, August 1-2, 2012.

81. Khan AA, Tallent S, Akiyama T, Gurley B, Summage-West C. Rapid isolation and

indentification of toxin producing Bacillus cereus from dietary supplements. American Society for Microbiology, Denver, CO, May 18-21, 2013.

82. Chen SM, Atchley DH, Murphy MA, Gurley BJ, Kamdem LK. Impact of UGT2B17

genetic polymorphisms on the disposition of exemestane in healthy volunteers. Clinical Pharmacology & Therapeutics, 2013;93(Suppl 1):S25.

ABSTRACTS (cont.)

83. Gurley BJ. Phytochemical modulators of human drug metabolism: an introduction to

clinically relevant herb-drug interactions. Planta Medica, 2014;80:755 (abstract IL27).

84. Hammond D, Thano E, Bohnenberger K, McAllister M, Wannenburg T, Hsu S, Gurley

B, Kim R. Ventricular tachycardia precipitated by the use of diet supplement Hydroxycut Gummies™ American College of Clinical Pharmacy, Global Conference on Clinical Pharmacology. San Francisco, CA, October 17-21, 2015. (abstract #35386.)

85. Wang X, Zhu H-J, Munoz J, Gurley BJ, Markowitz JS. An ex vivo approach to

botanical-drug interactions: A proof of concept study. 18thAnnual Meeting of the College of Psychiatric and Neurologic Pharmacists (CPNP) April 19th- 22nd 2015, Tampa, FL 86. Olivetto A, Gurley B. “Impact of CYP2D6 phenotype on response to

methamphetamine in healthy volunteers.” College on Problems of Drug Dependency, Phoenix, AZ, June 16, 2015. (abstract # 2174472)

87. Gurley BJ. Multi-ingredient, caffeine-containing dietary supplements: history, efficacy,

and safety. Planta Medica, 2016;82,DOI:10.1055/s-0036-1578599 (abstract #OA29).

BOOKS & BOOK CHAPTERS

1. Gurley B. and Hagan D. “Herb-drug Interactions” in Handbook of Food and Drug

Interactions, B. McCabe, E. Frankel, and J. Wolfe, eds., CRC Press, Boca Raton, 2003, pp. 259-293.

2. Gurley B. “Alternative Medicines for Golfers: Safety, Efficacy, and Herb-drug

Interactions” in Golf Forever, T. Glenn Pait, ed., Stephens Media, 2003. 3. Herb-Drug Interaction Handbook. 3rd Edition. Sharon M. Herr (Veronica S.L. Young.

Edzard Ernst, and Bill J. Gurley, eds.) Church Street Books, Castleton, NY. 2005. 4. Gurley BJ, Fifer EK, Gardner Z. “Phytochemical Modulators of Human Drug

Metabolism: Drug Interactions with Fruits, Vegetables and Botanical Dietary Supplements” in Encyclopedia of Drug Metabolism and Interactions, L. Wienkers, ed., John Wiley & Sons, Inc. Hoboken, NJ (published online May15, 2012).

5. Turfus SC, Delgoda R, Picking D, Gurley BJ. "Pharmacokinetics" in Pharmacognosy,

J. McCreath ed., Elsevier, Inc. (in press, 2017). 6. Gurley BJ, Kingston R, Thomas SL. "Caffeine-containing Energy Drinks/Shots:

Safety, Efficacy, and Controversy" in Sustained Energy for Enhanced Human Functions and Activity, D. Bagchi ed., Elsevier/Academic Press (in press, 2017)

BOOK FOREWARDS

1. Gurley BJ. Villainous Compounds: Chemical Weapons and the American Civil War,

by Guy Hasegawa. Southern Illinois Press, Carbondale, 2015. BOOK REVIEWS 1. Gurley BJ. Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and

Their Components (Mahendra Rai and Kateryna Kon eds.) Academic Press, 2013. Review published in HerbalGram. 2014;101:76-77.

INVITED PRESENTATIONS AND LECTURES 1. "Influence of Organ Transplantation on Cyclosporine Pharmacokinetics", Department

of Chemistry, Memphis State University, April 6, 1990. 2. "Influence of Organ Transplantation on Cyclosporine Pharmacokinetics", Department

of Chemistry, University of Arkansas at Pine Bluff, February 5, 1991. 3. "Effect of Hepatic Reperfusion Injury on Lipoprotein Metabolism and Cyclosporine

Pharmacokinetics", Departments of Surgery and Endocrinology, University of Tennessee, Memphis, April 6, 1991.

4. "Effects of Ionizing Radiation on Drug Disposition", NASA Johnson Space Center,

Houston, TX, February 19, 1992. 5. "Basic Clinical Pharmacokinetics" Veterans Administration Short Course in Clinical

Pharmacokinetics, Fort Roots V.A. Hospital, North Little Rock, AR, July 7-9, 1992. 6. "Basic Clinical Pharmacokinetics" Veterans Administration Short Course in Clinical

Pharmacokinetics, Fort Roots V.A. Hospital, North Little Rock, AR, August 3-11, 1997.

7. “The Impact of Ischemia-reperfusion Injury on Hepatic Drug Clearance,” G. D. Searle

Co., Skokie, IL, October 21, 1997. 8. “Influence of Ischemia-reperfusion Injury on Hepatic Drug Clearance,” UAMS

Pharmaceutical Sciences Seminar Course, Little Rock, AR, January 30, 1998. 9. “Influence of Ischemia-reperfusion Injury on Hepatic Drug Clearance,” Northeast

Louisiana University, College of Pharmacy, Spring Seminar Series, Monroe, LA , April 17, 1998.

10. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” National

Center for Toxicological Research, Jefferson, AR, February 9, 1999. 11. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” Central

Arkansas Chapter of Sigma Xi (“The Sigma Xi Seminar Series”), University of Arkansas at Little Rock, Little Rock, AR, September 28, 1999.

INVITED PRESENTATIONS AND LECTURES (cont.)

12. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” Jackson-

Madison County General Hospital (“Medical Rounds”), Jackson, TN, October 19, 1999.

13. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” UAMS,

College of Nursing, Little Rock, AR, March 23, 2000. 14. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” Mid-South

College of Clinical Pharmacy, Little Rock, AR, April 25, 2000. 15. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” Nutrition

and Aging XV: Alternative Nutrition Therapies for the Elderly, Little Rock, AR, September 13, 2000.

16. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” University

of Tennessee College of Pharmacy, Department of Pharmaceutical Sciences Fall Seminar Series, Memphis, TN, October 2, 2000.

17. “Herbal Dietary Supplements: Pharmacokinetic and Pharmacodynamic Herb/Drug

Interactions,” Prevention Strategies for Better Patient Outcomes, The Ritz-Carlton, Dearborn, MI, February 23, 2001.


Interactions,” Complementary and Alternative Medicine Course, UAMS Center on Aging, Little Rock, AR, March 7, 2001.


Interactions,” Arkansas Society for Parenteral and Enteral Nutrution, University of Arkansas for Medical Sciences, Little Rock, AR, April 19, 2001.

20. “Clinical Impact of Drug-Nutraceutical Interactions,” 4th Annual International

Conference on Drug Metabolism/Applied Pharmacokinetics, Devil’s Head Resort, Merrimac, Wisconsin, September 11-14, 2001.

21. “Herbal Dietary Supplements and Transplant Medications,” National Institute of

Digestive Diseases and Kidney, National Institutes of Health, Bethesda, MD, September 28, 2001.

22. “Herbal Dietary Supplements and Transplant Medications,” 13th Annual Advances in

Transplantation, Washington, DC, September 29, 2001. 23. “Toxicity of multi-component ephedra-containing dietary supplements.” 16th Annual

American Association of Pharmaceutical Scientists meeting. Denver, CO, October 21-25, 2001.

24. “Clinical Impact of Drug-Nutraceutical Interactions,” Chaldean American Association

of Health Care Professionals, Southfield, MI, February 1, 2002. 25. “Clinical Impact of Drug-Nutraceutical Interactions,” Arkansas Nutrition and

Environmental Studies Alliance (ANESA), Little Rock, AR, February 13, 2002. INVITED PRESENTATIONS AND LECTURES (cont.)

26. “Clinical Impact of Drug-Nutraceutical Interactions,” Detroit Medical Center, Grand

Rounds, Detroit, MI, April 10, 2001. 27. “Herb-drug interactions,” Part of a regional teleconference entitled “Drug Use &

Misuse in the Elderly.” Sponsored by the Arkansas Geriatric Education Center. Little Rock, AR, April 29, 2002.

28. “Herb-drug interactions,” University of Arkansas Cooperative Extension Service,

Ferndale, AR, May 2, 2002. 29. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” A public

lecture in conjunction with the Medical Education at the Old State House exhibit. The Old State House Museum, Little Rock, AR, May 14, 2002.

30. “Herbal Dietary Supplements: A Pharmaceutical Scientist’s Perspective,” Keynote

speaker for the Lawrence M. Fetterman Lecture Series, The Providence Foundation, Mobile, AL, May 21, 2002.

31. “Clinical Impact of Drug-Nutraceutical Interactions,” Providence Hospital, Grand

Rounds, Mobile, AL, May 22, 2002. 32. “What You Need to Know About Dietary Supplements,” part of an interactive

statewide television broadcast entitled Well Connected to Health in Your Hometown and produced by the University of Arkansas for Medical Sciences, September 17, 2002.

33. “Grapefruit Juice and Botanical Supplements: Common Dietary Sources of Drug

Interactions,” 85th Annual Meeting of the American Dietetic Association, Food & Nutrition Conference & Exhibition, Philadelphia, PA, October 20, 2002.

34. “Toxicity of multi-component ephedra-containing dietary supplements.” Toxicology

Study Section and Review Committee (TSSRC) Meeting, National Center for Toxicological Research, Jefferson, AR, October 29, 2002.

35. “Botanical Supplements: A Source of Drug Interactions in the Elderly” 22nd Annual

Arkansas Aging Conference. Hot Springs, AR, November 8, 2002. 36. “Dietary Supplements: A Pharmaceutical Scientist’s Perspective” UAMS Preventative

Nutrition Project Seminar Series, Little Rock, AR, December 12, 2002. 37. “The Effects of Herbal Medication on Patient Care” North Arkansas Regional Medical

Center, Harrison, AR, January 23, 2003. 38. “The Truth About Over-The-Counter Weight-Loss Products” UAMS Weight Loss

Seminar Series, UAMS College of Medicine, Little Rock, AR, February 1, 2003. 39. “The Effects of Herbal Medication on Patient Care” St. Vincent’s Hospital, Little Rock,

AR, March 20, 2003. 40. “Interactions of Prescription Drugs and Herbs” 2003 Arkansas Extension

Homemakers Council (AEHC) Convention, Hot Springs, AR, June 11, 2003. INVITED PRESENTATIONS AND LECTURES (cont.)

41. “Herb-drug Interactions” American Dietetic Association, April 16, 2003, Philadelphia,

PA. 42. “Botanical Supplement Approaches to Treating Alzheimer’s Disease.” Second Annual

Alzheimer’s Disease Center Professional Education Day. D. W. Reynolds Center on Aging, Little Rock, AR, September 12, 2003.

43. “Dietary Supplements: A Pharmaceutical Scientist’s Perspective” Department of

Chemistry Seminar Series, Arkansas State University, Jonesboro, AR, October 1, 2003.

44. “The Truth About Over-The-Counter Weight-Loss Products: A Focus on Dietary

Supplements” Arkansas Rural Hospital CME Program, UAMS College of Medicine, Little Rock, AR, January 13, 2004.

45. “The Effects of Herbal Medication on Patient Care: A Focus on Herb-Drug

Interactions.” UAMS, Graduate School of Nursing, Little Rock, AR, January 21, 2004. 46. “Drugs Disguised as Supplements: The Ephedra Controversy. American Academy of

Forensic Sciences, Dallas, TX, February 17, 2004. 47. “Drugs Disguised as Supplements: Seven Years of Research into Herb/Drug

Interactions and Ephedra Supplements. Dean’s Council, UAMS College of Pharmacy, Little Rock, AR, April 27, 2004.

48. “Dietary Supplements: A Focus on Herb-Drug Interactions. Chancellor’s Circle

Lecture, Donald W, Reynolds Center on Aging, Little Rock, AR, June 9, 2004. 49. “Dietary Supplements: A Focus on Herb-Drug Interactions in the Elderly. UAMS

Center on Aging Journal Club, Donald W, Reynolds Center on Aging, Little Rock, AR, June 17, 2004.

50. “Dietary Supplements: A Focus on Herb-Drug Interactions. UAMS Pharmacy

Continuing Education lecture, Phillips Community College, Helena, AR, August 1, 2004.

51. “Can I take this with my Ambien?: A Primer on Herb-Drug Interactions.”. UAMS,

Dept. of Anesthesiology “Grand Rounds.” Little Rock, AR, September 20, 2004. 52. “Herb-drug Interactions: Clinical Relevance.” UAMS Complementary and Alternative

Medicine Journal Club. Little Rock, AR, September 23, 2004. 53. “Herb-Drug Interactions: an update for practitioners. Southeastern Michigan Society

of Health-Systems Pharmacy, Detroit, MI, October 13, 2004. 54. “Herb-Drug Interactions: an update for practitioners.” “Grand Rounds” Arkansas

Children’s Hospital, Little Rock, AR, January 18, 2005. 55. “Drugs Disguised as Supplements: A Focus on Herb-Drug Interactions.” Dean’s

Council, UAMS College of Pharmacy, Little Rock, AR, April 25, 2005. INVITED PRESENTATIONS AND LECTURES (cont.)

56. “Herb-Drug Interactions: an update for practitioners.” Oklahoma/Arkansas Bi-state

Regional Clinical Laboratory Science Meeting, Little Rock, AR, May 9, 2005. 57. “Can I take this with my Prozac? A Primer on Herb-Drug Interactions.” “Grand

Rounds” UAMS, Dept. of Psychiatry, Little Rock, AR, June 29, 2005. 58. “Herb-Drug Interactions: An update for practitioners.” UAMS Pharmacy Continuing

Education lecture, UAMS College of Public Health, Little Rock, AR, July17, 2005. 59. “Drugs Disguised as Supplements: A Focus on Herb-Drug Interactions.” International

Conference on Quality and Safety Issues Related to Botanicals, University of Mississippi, Oxford, MS, August 17, 2005.

60. “Herb-Drug Interactions: An update for practicing dietitians.” Northwest Arkansas

District Dietetics Association, Springdale, AR, September 16, 2005. 61. “Can my child take this with his Ritalin? A Primer on Herb-Drug Interactions.” “Grand

Rounds” Children’s Mercy Hospital, Kansas City, MO. November 4, 2005. 62. “Dietary Supplements: A Focus on Herb-Drug Interactions in the Elderly.” 4th Annual

Symposium: Caring for Older Adults, Texarkana Regional Center on Aging, Texarkana, AR, January 28, 2006.

63. “Hemodynamic and electrocardiographic effects of an ‘Ephedra-free’ dietary

supplement (Metabolife Ultra™).” 2006 Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics. Baltimore, MD, March 9, 2006.

64. “Clinically Relevant Herb-Drug Interactions.” Symposium on Critical Care and

Emergency Medicine, Arlington Resort Hotel, Hot Springs, AR, March 30, 2006. 65. “Can I take this with my Prozac? A Primer on Herb-Drug Interactions.” Rural Hospital

Program (Statewide presentation via teleconference). Little Rock, AR, July 8, 2006. 66. “Dietary Supplements and Drug Interactions.” UAMS College of Medicine, Medicinal

Pharmacology Course, Little Rock, AR, December 12, 2006 67. “Herb-Drug Interactions: An Update for Practitioners.” UAMS, College of Medicine,

Complementary & Alternative Medicine Course, Little Rock, February, 27, 2007. 68. “Interactions Between Supplements and Drugs.” Current Issues and Recent

Developments in Dietary Supplement Research: An Intensive Practicum. Office of Dietary Supplements, National Institutes of Health, Bethesda, MD, May 22, 2007.

69. “Can I take this with my Prozac? An Introduction to Herb-Drug Interactions.”

Pennington Biomedical Research Center, Baton Rouge, LA, September 6, 2007. 70. “Can I take this with my Prozac? An Introduction to Herb-Drug Interactions for

Dietitians.” UAMS, Dept. of Nutrition & Dietetics, Little Rock, AR, January 10, 2008. INVITED PRESENTATIONS AND LECTURES (cont.)

71. “Botanicals and Prescription Medications: Think Twice Before Mixing.” Part of a free

community educational event entitled “Food as Medicine…plants and your health.” Pennington Biomedical Research Center, Baton Rouge, LA, January 31, 2008.

72. “Can I take this with my Prozac? An Introduction to Herb-Drug Interactions for

Dietitians.” Adult Care Acute Care Practitioners, UAMS College of Nursing, Little Rock, AR, February 6, 2008.

73. “Yankee Bullets, Rebel Blood: A glimpse into Confederate medical care in Arkansas

during the Civil War.” UAMS College of Pharmacy, Pharmaceutical Sciences Seminar Series, Little Rock, AR, April 25, 2008.

74. “Yankee Bullets, Rebel Blood: A glimpse into Confederate medical care in Arkansas

during the Civil War.” UAMS College of Medicine, Dept. of Internal Medicine Seminar Series, Little Rock, AR, May 30, 2008.

75. “Interactions Between Supplements and Drugs.” Dietary Supplements Practicum.

Office of Dietary Supplements, National Institutes of Health, Bethesda, MD, June 10, 2008.

76. “Will this interact with my child’s Adderal? An Introduction to Herb-Drug Interactions

for Pediatricians.” Arkansas Children’s Hospital Research Institute, Little Rock, AR, June 12, 2008.

77. “Assessing the clinical significance of herb-drug interactions: in vitro, in vivo, in silico,

and sometimes infuriating.” Amgen, Pharmacokinetics & Drug Metabolism Group, Seattle, WA, August 29, 2008.

78. “…And are you taking any herbal dietary supplements? An Introduction to Herb-Drug

Interactions for Anesthesiologists.” UAMS, Dept. of Anesthesiology, Little Rock, AR, September 2, 2008.

79. “Can I take this with my Prozac? An Introduction to Herb-Drug Interactions for Nurse

Practitioners.” National Conference of Gerontological Nurse Practitioners, St. Louis, MO, September 25, 2008.

80. “Can I take this with my Prozac? An Introduction to Herb-Drug Interactions” American

Chemical Society, Southwestern Regional Meeting, Little Rock, AR, October 2, 2008. 81. “Civil War Treasures in the UAMS History of Medicine Collection,” UAMS History of

Medicine Associates, Little Rock, AR, October 2, 2008. 82. “Herbal Dietary Supplements: The Good, the Bad, and the Ugly.” UAMS, College of

Nursing, Little Rock, AR, March 9, 2009. 83. “Introduction to Dietary Supplements and Herb-Drug Interactions.” Arkansas

Academy of Physicians Assistants, Fayetteville, AR, April 17, 2009. 84. “Dietary Supplements and Diabetes: Sweet or Sour?” 16th Annual Diabetes Update

2009, UAMS College of Medicine, Little Rock, AR, April 18, 2009. INVITED PRESENTATIONS AND LECTURES (cont.)

85. “Alternative Medicine and Autism: Efficacy & Safety”, National Association of

Pediatric Nurse Practitioners (Spring Conference), Arkansas Children’s Hospital, Little Rock, AR, April 25, 2009.



87. “Dietary Supplement Use and Herb-Drug Interactions in Older Adults.” Regional

Elder Abuse, Advocacy & Caregiver Training (REACT) Conference, Texarkana, AR, June 5, 2009.

88. “Confessions of a P&T Chair.” UAMS, College of Pharmacy, Faculty Retreat, Little

Rock, AR, August 6, 2009. 89. “An Introduction to Dietary Supplement Safety and Efficacy.” Arkansas Agricultural

Extension Service, Little Rock, AR, December 3, 2009. 90. “Herbal Dietary Supplements: The Good, the Bad, and the Ugly.” Arkansas

Gerontological Society, Little Rock, AR, April 1, 2010. 91. “Dosage Form Performance: An Overlooked Determinant of Phytochemical Efficacy

and Safety.” 9th Annual Oxford International Conference on the Science of Botanicals, Oxford, MS, April 13, 2010.



93. “Interactions Between Supplements and Drugs.” UAMS Rural Hospitals Program,

Little Rock, AR, June 22, 2010. 94. “Interactions Between Botanical Dietary Supplements and Prescription Medications.”

11th Annual Geriatrics & Long Term Care Update, DW Reynolds Institute on Aging, Little Rock, AR, September 19, 2010.

95. “Herbal Medicines and Drug Interactions,” 9th Annual Florence C. Zook Oncology

Symposium, Winthrop P. Rockefeller Cancer Center, Little Rock, AR, October 22, 2010

96. “An Introduction to Botanical/Drug Interactions,” UAMS Department of Family and

Preventative Medicine Grand Rounds, Little Rock, AR, March 15, 2011. 97. “Interactions Between Supplements and Drugs.” Mary Ann Picciano Memorial Dietary

Supplements Practicum. Office of Dietary Supplements, National Institutes of Health, Bethesda, MD, June 7, 2011.

98. “Herbal Supplements and Common Drug Interactions in Older Adults.” National

Gerontological Nursing Association, Little Rock, AR, October 7, 2011. INVITED PRESENTATIONS AND LECTURES (cont.)

99. “Botanical Dietary Supplements: The Good, the Bad and the Ugly.” American

Chemical Society, Harding University, Searcy, AR, November 15, 2011. 100. “Phytochemical Modulators of Human Drug Metabolism: Herb-drug Interactions and

their Clinical Relevance.” Department of Biology, University of Arkansas at Little Rock, November 21, 2011.

101. “An Introduction to Clinically Important Herb-Drug Interactions.” PedsPlace: a

Continuing Medical Education Forum, Arkansas Children’s Hospital, Little Rock, AR, March 22, 2012.

102. “Evaluating the Clinical Relevance of Human Dietary Supplement-Drug Interaction

Study Designs.” Dietary Supplement-Drug Interactions Workshop. National Institutes of Health, Bethesda, MD, March 27, 2012.

103. “Phytochemical Modulators of Human Drug Metabolism: An Introduction to Herb-Drug

Interactions.” American Council for Medicinally Active Plants, 3rd Annual Conference, Arkansas State University, Jonesboro, AR, May 23, 2012.

104. “Interactions Between Supplements and Drugs.” Mary Ann Picciano Memorial Dietary


105. “Significance of Dissolution Testing for Botanical Dosage Forms.” Challenges in

Dissolution Workshop, United States Pharmacopeia, Rockville, MD, June 12, 2012. 106. “Botanical Dietary Supplements: The Good, the Bad, and the Ugly.” Department of

Dietetics and Nutrition Seminar. University of Arkansas for Medical Sciences, November 8, 2012.

107. “Emerging Technologies for Improving Phytochemical Bioavailability: Benefits and

Risks.” Botanicals and Translational Medicine (an NIH-sponsored symposium). Pennington Biomedical Research Center, Baton Rouge, LA, February 7, 2013.

108. “Introduction to Botanical Dietary Supplements: Safety and Efficacy.” Arkansas

Society of Geronotological Nurses. University of Arkansas for Medical Sciences, Little Rock, AR, February 13, 2013.

109. “Criteria for advancing in vitro herb-drug interaction data to clinical study.” Dietary

Supplement Drug Interaction Expert Panel Meeting. National Center for Complementary and Alternative Medicine, Rockville, MD, April 1, 2013.



111. “Clinical Utility of Dietary Supplement Case Reports: A Pharmaceutical Scientist’s

Perspective.” The Toxicology Forum, Aspen, CO, July 8, 2013. INVITED PRESENTATIONS AND LECTURES (cont.)

112. “Herbal Dietary Supplements: The Good, the Bad, and the Ugly.” American Academy

of Professional Coders, Little Rock Central Arkansas Chapter, Little Rock, AR, July 19, 2013.

113. “Dietary Supplements and the Adolescent Athlete.” PedsPlace (grand rounds)—

Arkansas Children’s Hospital. Little Rock, AR, August 1, 2013. 114. “How the IACUC Evaluates Pain and Distress.” Division of Laboratory Animal

Medicine Workshop for New Investigators. UAMS, Division of Laboratory Animal Medicine, Little Rock, AR, September 25, 2013.

115. “Dietary Supplements and the Adolescent Athlete: Safety and Efficacy.” UAMS Dept.

of Nutrition and Dietetics Seminar, Little Rock, AR, October 4, 2013. 116. “’Can I take this with my Prozac®’: An Introduction to Clinically Relevant Herb-Drug

Interactions.” Department of Medicinal Chemistry Seminar, University of Minnesota College of Pharmacy, Minneapolis, MN, October 29, 2013.

117. “Dietary Supplements and the Adolescent Athlete: Safety and Efficacy.” Natural

Products and Dietary Supplements Course (guest lecture), University of Minnesota College of Pharmacy, Minneapolis, MN, October 31, 2013.

118. “History Repeats Itself: Botanical Dietary Supplements and the American Civil War.”

Natural Products and Dietary Supplements Course (guest lecture), University of Minnesota College of Pharmacy, Minneapolis, MN, October 31, 2013.

119. “Dietary Supplements and the Adolescent Athlete: Safety and Efficacy.” Department

of Pharmacotherapy and Translational Research Seminar, University of Florida College of Pharmacy, Gainesville, FL, November 14, 2013.


Perspective.” Health Canada Seminar Series, Health Canada, Ottawa, Canada, November 21, 2013.

121. “Herbal Dietary Supplements: The Good, the Bad, and the Ugly.” UAMS College of

Pharmacy Continuing Education Series. University of Arkansas for Medical Sciences, Little Rock, AR, December 1, 2013.

122. “Herbal Dietary Supplements: Efficacy and Safety.” UAMS College of Nursing,

Gerontological Nursing Seminar, University of Arkansas for Medical Sciences, Little Rock, AR, February 12, 2014.

123. “Clinically Relevant Herb-Drug Interactions: Past, Present & Future.” National Center

for Complementary and Alternative Medicine, Integrative Medicine Research Lecture. National Institutes of Health, Bethesda, MD, March 10, 2014.


Perspective.” Society of Toxicology, 53rd Annual Meeting, Phoenix, AZ, March 24, 2014.


125. “Clinically Relevant Herb-Drug Interactions.” 36th Annual Family Medicine Intensive

Review Course. University of Arkansas for Medical Sciences, Little Rock, AR, May 16, 2014.



127. “Phytochemical Modulators of Human Drug Metabolism: An Introduction to Clinically

Relevant Herb-drug Interactions.” American Society of Pharmacognosy, 55th Annual Meeting, Oxford, MS, August 5, 2014.

128. “Clinically Relevant Herb-Drug Interactions: Past, Present & Future.” North American

Congress of Clinical Toxicology. New Orleans, LA, October 19, 2014. 129. “Emerging Technologies for Improving Phytochemcial Bioavailability: Benefits and

Risks.” International Conference on the Science of Botanicals, 15th Annual Meeting, Oxford, MS, April 14, 2015.

130. "Cinnamomum cassia: Safety and Efficacy Review." United States Pharmacopoeia's

Expert Panel on Dietary Supplements, Rockville, MD, May 7, 2015. 131. "Dietary Supplement Dosage Form Performance: An Overlooked Parameter in

Assessing Clinical Efficacy and Safety of Natural Products." The Toxicology Forum, 41st Annual Summer Meeting, Colorado Springs, CO, July 15, 2015.

132. "Botanical Dietary Supplements: the Good, the Bad and the Ugly." South Central

Chapter of the Medical Librarians Association, Little Rock, AR, October 4, 2015. 133. "Clinically Relevant Herb-Drug Interactions: Past, Present, and Future." Dietetics and

Nutrition Seminar, UAMS College of Health Related Professions, Little Rock, AR, October 8, 2015.

134. "'We're From the IACUC and We're Here to Help:' A Brief Summary of IACUC-related

Issues Commonly Found in Animal Use Protocols Requiring Revisions" UAMS IACUC Seminar Series, Little Rock, AR, October 13, 2015.

135. “Phytochemical Modulators of Human Drug Metabolism: An Introduction to Herb-Drug

Interactions.” Advanced Practice Registered Nurse Seminar, Arkansas Children's Hospital, Little Rock, AR, December 10, 2015.

136. "Clinically Relevant Herb-Drug Interactions: Past, Present, and Future." Graduate

Nursing Seminar, UAMS College of Nursing, Little Rock, AR, February 24, 2016. 137. "Multi-ingredient, Caffeine-containing Dietary Supplements: History, Safety, Efficacy."

16th Annual International Conference on the Science of Botanicals, Oxford, MS, April 12, 2016.


138. "Practical Considerations when Designing Clinical Pharmacokinetic Herb-drug

Interaction Studies." National Toxicology Program workshop: "Addressing Challenges in the Assessment of Botanical Dietary Supplement Safety," National Institutes of Health, Bethesda, MD, April 26, 2016.

139. "From Benchtop to Walmart: The 30-year Odyssey of Omnibalm®," Health Science

Entrepreneurship Bootcamp sponsored by NIGMS Systems Pharmacology and Toxicology T32 Training Program, UAMS Translational Research Institute, and UAMS Bioventures, Little Rock, AR, August 10, 2016.

140. "Multi-ingredient, Caffeine-containing Dietary Supplements: History, Safety, Efficacy."

UAMS Department of Dietetics and Nutrition Seminar Series, Little Rock, AR September 8, 2016.

141. "'Can I take this with my Prozac?": An introduction to clinically relevant herb-drug

interactions. University of Minnesota, College of Pharmacy, Minneapolis, MN, October 6, 2016.

142. "Before They Were Dietary Supplements: Botanical Medicine and the American Civil

War." University of Minnesota, College of Pharmacy, Minneapolis, MN, October 6, 2016.

GRANTS AND CONTRACTS (funded) (National Institutes of Health) 1. Aging and CYP-mediated herb-drug interactions. Bill Gurley, principal investigator;

$73,000; National Institute on Aging. (Grant Number 1-RO3-AG17733-01) 1999. 2. Age-related changes in blood brain barrier P-glycoprotein function. Mark Luer,

principal investigator; Bill Gurley, co-investigator; $72,927; National Institute on Aging. (Grant Number 1-RO3-AG16435-01) 2000.

3. Pharmacological and Pharmacokinetic Evaluation of Oxazolidines as Potential

Sympathomimetic Prodrugs. Richard Walker, principal investigator, BJ Gurley, consultant; $103,600; National Institutes of General Medical Sciences (Grant Number 1-RO3-GM56382-01A2) 2000-2002

4. Clinical assessment of herb-drug interactions. Bill Gurley, principal investigator.

$899,646 National Institute for General Medical Sciences (Grant Number 1-RO1-GM71322-01A2) 2003–2007.

5. Impact of CYP2D6 phenotype on response to methamphetamine in humans. Alison

Oliveto, prinicipal investigator, BJ Gurley, co-investigator. $405,000 National Institute for Drug Abuse (Grant Number 1-R21-DA031837) 2012-2104.

GRANTS AND CONTRACTS (funded) 1. Radiation Protection and Radiation Recovery Activities of Essential Metalloelement

Complexes. JRJ Sorenson, LW Chang, BJ Gurley, and LSF Soderberg, principal investigators; $10,000; Arkansas Space Grant Consortium

GRANTS AND CONTRACTS (funded) cont.

2. The Effect of Renal Ischemia-reperfusion Injury on Hepatic Drug Clearance. BJ

Gurley, principal investigator; $7,828; UAMS Medical Research Foundation and the Murphy Oil Corporation

3. A Randomized, Multicenter, Three Month, Double-blind, Pharmacokinetic, Safety and

Tolerability Study of Sandimmune Neoral Soft Gelatin Capsules in Postoperative Primary Renal Transplant Patients. G Barone, principal investigator, and BJ Gurley, co-investigator; $269,000; Sandoz Pharmaceutical Corp.

4. The Effect of Intestinal Ischemia-Reperfusion Injury on Hepatic Oxidative Drug

Metabolism. BJ Gurley, principal investigator; $12,000; R. Clifton Brooks Medical Research Fellowship (USCV)

5. The Effect of Extrahepatic Ischemia-reperfusion Injury on Hepatic Oxidative Drug

Metabolism. BJ Gurley, principal investigator; $7,500; American Association of Colleges of Pharmacy New Investigator Grant

6. Do Standard Dosage Regimens of Ganciclovir Eliminate HSV-tk Transduced

Lymphocytes? WJ McIntyre, principal investigator, and BJ Gurley, co-investigator; $10,017; American College of Clinical Pharmacy

7. A Study of the Steady State Pharmacokinetics of Itraconazole and

Hydroxyitraconazole in Pediatric Patients; Paul Gubbins, principal investigator, and Bill Gurley, co-investigator; $7,550; UAMS Medical Research Foundation

8. Identification of a new itraconazole metabolite in human serum. Bill Gurley and Paul

Gubbins (faculty co-sponsors); $3,483; SILO Advisory Council Undergraduate Research Fellowship

9. Competetive inhibition of gabapentin brain uptake in the rat. Mark Luer, principal

investigator; Bill Gurley, co-investigator; $9,900; American College of Clinical Pharmacy

10. The effect of interleukin-6 on hepatic metabolism of the triazole itraconazole. Paul

Gubbins, principal investigator; Bill Gurley co-investigator; $20,000; Society of Infectious Disease Pharmacists

11. The steady state pharmacokinetics of itraconazole solution in autologous bone

marrow transplant recipients. Paul Gubbins, principal investigator; Bill Gurley,co-investigator; $12,500; American Association of Colleges of Pharmacy

12. Methylphenidate transdermal device for the treatment of attention deficit hyperactivity

disorder (ADHD) in children. Ken Miller, principal investigator; Bill Gurley, co-investigator; $8,000; UAMS Medical Research Foundation

13. Effect of grapefruit juice on the systemic availability of itraconazole capsules. Paul

Gubbins, principal investigator; Bill Gurley, co-investigator; $10,000; American College of Clinical Pharmacy


14. Age-related changes in blood brain barrier P-glycoprotein function. Mark Luer,

principal investigator Bill Gurley, co-investigator; $12,500; American Association of Colleges of Pharmacy

15. Acute phase response and blood brain barrier P-glycoprotein function. Mark Luer,

principal investigator; Bill Gurley, co-investigator; $14,998; UAMS Medical Research Foundation, 1998.

16. Age-related changes in blood brain barrier P-glycoprotein function. Bill Gurley, faculty

sponsor; $5,000; Pharmaceutical Research and Manufacturers of America Foundation, Undergraduate Research Fellowship in Pharmaceutics, 1998.

17. Assessment of potential interactions between herbal dietary supplements and

conventional medications. Bill Gurley, principal investigator; $52,516; Gustavus and Louise Pfeiffer Research Foundation, 1999.

18. Comparative assessment of Co-enzyme Q10 formulations. Bill Gurley and Indra

Reddy , co-principal investigators. $26,000; Tishcon Corp, 2000. 19. Determining the influence of intestinal CYP3A4 and P-glycoprotein on the oral

bioavailability of itraconazole capsules. Paul Gubbins; principal investigator; Bill Gurley, co-investigator; $29,287; Society of Infectious Disease Pharmacists, 2000.


conventional medications II (renewal). Bill Gurley, principal investigator; $53,733; Gustavus and Louise Pfeiffer Research Foundation, 2001.


conventional medications III (renewal). Bill Gurley, principal investigator; $62,818; Gustavus and Louise Pfeiffer Research Foundation, 2002.

22. Bioflavonoids in herbal supplements. Anne Grippo and Bill Gurley, co-principal

investigators; $17,367; Biomedical Research Infrastructure Network (BRIN) Grant, 2002.

23. Nicotine and ephedrine interactions: Effects on the cardiovascular system. Anne

Grippo, Bill Gurley, and Stephanie Gardner co-principal investigators. $219,320; Arkansas Biosciences Institute, 2003.

24. Nictoine and ephedrine interactions: Identification of cardiovascular active agent(s)

and sites of cellular toxicity. Anne Grippo, Bill Gurley, and Stephanie Gardner co-principal investigators. $147,490; Arkansas Biosciences Institute, 2004.

25. Cardiovascular effects of “Ephedra-free” dietary supplements. Bill Gurley (faculty

sponsor). $5,000, American Foundation for Pharmaceutical Education. April 15, 2004.

26. Hemodynamic and electrocardiographic effects of ephedra-free dietary supplements.

Bill Gurley, principal investigator. $75,000; Gustavus and Louise Pfeiffer Research Foundation, 2006.


27. Omnibalm® as wound therapy for lower extremity ulcers in diabetics. Bill Gurley,

consultant. $50,000; UAMS Translational Research Institute, 2012. 28. “Northern Bullets, Southern Blood”: The illustrated medical casebook of Dr. Henry M.

Dye, Confederate surgeon in the Trans-Mississippi Department. Bill Gurley, principal investigator. $1,500; The Society for the History of Medicine and the Health Professions, UAMS Library Research Grant, 2014.

29. Analysis of hepatotoxicity of the dietary supplement OxyELITE Pro in a mouse

model. $301,000; Bill Gurley and Igor Koturbash, co-principal investigators; Department of Justice contract, 2016.

GRADUATE STUDENTS DIRECTED 1. Nasser N. Nyamweya, “Cocaine pharmacokinetics in neonatal rats,” Masters thesis

committee member (1993-1996). 2. Haijuan Yang, “Comparative pharmacokinetics of methadone in neonatal rats

following intragastric intubation using various nutrient vehicles,” Masters thesis committee member (1993-1996).

3. Maisaa Khalil, “The patterns of dietary supplement use among breast cancer patients

in the Arkansas Cancer Research Center.” Masters thesis committee member (1999-2000).

4. Martha Hubbard, “Modulatory effects of eight popular dietary supplements on human

cytochrome P450 phenotype.” Masters thesis advisor (2001-2003). 5. Kristina DeMarco, “Effect of Echinacea and Citrus aurantium on human cytochrome

P450 phenotypic ratios: Assessment of potential herb-drug interactions.” Masters thesis advisor (2001-2003).

6. Faith Hartsfield, “Clinical assessment of goldenseal and kava kava on human

cytochrome P450 activity: Comparison to clarithromycin and rifampin.” Masters thesis advisor (2004-2006).

7. Lyndsey Bryant, “Hemodynamic and electrocardiographic effects of ‘Ephedra-free’

dietary supplements in healthy volunteers.” Masters thesis advisor (2005-2007). 8. Michael Hambuchen, “Combination immunotherapy for early and continuous

protection from methamphetamine pharmacological effects.” Doctoral dissertation committee member (2010-2013).

9. Andrea Bell, "The effects of a high- versus low-daidzein diet on body weight,

kilocalorie intake, liver steatosis and serum adipokines in obese female Zucker rats." Masters thesis committee member (2014-2016).

SERVICE

A. UAMS, College of Pharmacy 1. Undergraduate Admissions Committee (1994 - 2000, 2006-present) 2. Student/Faculty Affairs Committee (1991- 2002) 3. Scholastic Standing Committee (1995 - 2002) 4. Graduate Committee (1995 - present) 5. Promotion and Tenure Committee (1995-2000, 2002-2004, Chair 2005-2011) 6. Executive Committee (1996 – 1998, 2014 – present) 7. Joint Pharm. D./Ph.D. Study Committee (1996 - present) 8. Pharmaceutical Sciences Seminar Course Committee (1996 - present) 9. Chairman (interim), Department of Pharmaceutics (9/1/1996 - 12/1/1998) 10. Assessment Committee (2002 - 2004, 2010 - 2015) 11. Curriculum Committee (2002 - 2004) B. University of Arkansas for Medical Sciences 1. Academic Senate Library Advisory Committee (1989 - present) 2. Academic Senate Honors Committee (1989 - 1995) 3. Institutional Animal Care and Use Committee (1992 - present, Chair 2010 -

present) 4. Committee on Assessment, UAMS Graduate School (1995 - 1998) 5. Tenure Task Force Committee (1997 - 2000) 6. Copyright Review Committee (1998 - 2004) 7. General Clinical Research Center (GCRC) Advisory Committee (2000 – 2007) 8. History of Medicine Associates (Board Member) (2001 – 2004) 9. Conflict of Interest Committee (2013 – present) C. State of Arkansas 1. UAMS representative to the Arkansas Science & Technology Authority (2011 —

2013) D. National 1. American Association of Pharmaceutical Scientists, Pharmacokinetics

Pharmacodynamics & Drug Metabolism Publicity Committee (1993 – 1994) 2. Chairman, Awards Committee, AAPS Southern Regional Discussion Group

(1998). 3. Chairman, AAPS Southern Regional Discussion Group (2002-2005, 2008, 2013) 4. Reviewer, NIH Study Section, Special Emphasis Panel (National Center for

Complementary and Alternative Medicine) July 12-14, 2000. 5. Invited participant for special FDA meeting (Ephedra: Establishing the Research

Plan), Washington, DC, March 4, 2003. 6. Selected to serve on the Scientific Program Committee for the American Society

of Clinical Pharmacology and Therapeutics. (2003-2004) 7. Invited to testify before the U.S. House of Representatives Committee on Energy

and Commerce (Subcommittee on Oversight and Investigations) on “Issues Relating to Ephedra-containing Dietary Supplements.” July 14, 2003.

8. Reviewer, NIH Study Section, Special Emphasis Panel (National Center for Complementary and Alternative Medicine) June 26-27, 2006.



SERVICE (cont.)

11. Editorial Board member for Clinical Pharmacology & Therapeutics (June 2009 - present).

12. United States Pharmacopeia Expert Committee for Botanical Dietary Supplements (June 2010 – 2015).

13. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) March 31-April 1, 2011

14. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) July 21- 22, 2011

15. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) July 9-10, 2012

16. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) January 16-18, 2013

17. Member, Dietary Supplement Drug Interaction Expert Panel (National Center for Complementary and Alternative Medicine) March 2012-present.

18. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) September 13, 2013.

19. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) November 19, 2013.

20. Reviewer, NIH Study Section (National Center for Complementary and Alternative Medicine) June 27, 2014.

21. United States Pharmacopeia Expert Committee for Non-botanical Dietary Supplements (June 2015 – present).

22. Reviewer, NIH Study Section (National Center for Complementary and Integrative Health) November 4, 2015.

23. United States Pharmacopoeia Dietary Supplement Admission Evaluations Joint Subcommittee (April 2016 – present).

E. International 1. Editorial Board member for Phytomedicine (July 2012 – present) F. Miscellaneous 1. Scientific Advisor to Global Partner Ventures and the Defense Enterprise Fund

(United States Department of State): Participated in the evaluation of former Soviet biological weapons facilities in St. Petersburg, Moscow, and Novosibirsk as part of a defense conversion effort to produce pharmaceutical agents instead of microbiological weapons packages. (1998 - 2000).

2. Chief Science Officer, Balm Innovations, LLC (a UAMS Bioventures company and maker of Omnibalm™, an OTC skin care product) (2005 - present).

3. Advisory Board Member to the American Botanical Council (2007 - present). 4. External Advisory Committee Member for NIH-sponsored Botanical Research

Center at the Pennington Biomedical Research Center in Baton Rouge, LA. (2008 - present).

5. Guest curator, Old State House Museum Civil War Sesquicentennial Exhibits, Little Rock, AR (2010 - present) “An Enduring Union” (Exhibit for 2011-2012), “Wall of Fire” (Exhibit for 2012-2013).

EXPERT WITNESS TESTIMONY

1. United States vs. Jim Cameron and The Chemmins Company—trial in Federal District Court,

Denver, CO. (ephedra): jury verdict for plaintiff (Colorado,1999) 2. Todd Weger vs. Next Nutrition, Inc.—deposition (Ultimate Orange, ephedra): hemorrhagic

stroke, case settled (Texas,1999) Plaintiff’s counsel: Mark Hefter Shields & Rusk 910 Lavaca Austin, TX 78701 3. Michael Van Howe vs. Twin Laboratories, Inc.—deposition (Ripped Fuel, ephedra): case

settled (Florida,1999) Plaintiff’s counsel: Stan Buky 515 N. Flagler Drive, Suite 300P West Palm Beach, FL 33401 4. Rosalie Talbert vs. E’Ola Inc.—deposition & trial in Anchorage, AK (Amp II Pro drops,

ephedra): ischemic stroke, jury verdict in favor of plaintiff (Alaska, 2000) Plaintiff’s counsel: Rick Vollertsen Atkinson, Conway & Gagnon 420 L Street, Suite 500 Anchorage, AK 99501-1989 5. Michael Ramsey vs. Smart Health Inc.—deposition (Herbal V Ultra, yohimbe): priapism, case

settled (California, 2000) Plaintiff’s counsel: Tim Ryan Tim Ryan & Associates 8072 Warner Ave. Huntington Beach, CA 29647 6. Travis Stephens vs. Twin Laboratories, Inc.—3 depositions & 1 Frye hearing in Tampa, FL

(Ripped Fuel, ephedra): seizures, case settled (Florida, 2001-2002) Plaintiff’s counsel: Greg Eiesland Johnson, Eiesland, Huffman & Clayborne 2201 Jackson Blvd, Suite 200 PO Box 6900 Rapid City, SD 57709-6900 7. Charles & Cora Scurlock vs. Twin Laboratories, Inc.—deposition & trial in Bastrop, TX

(Ripped Fuel, ephedra): heat stroke, jury verdict in favor of plaintiff (Texas, 2002) Plaintiff’s counsel: Mike Grimes Mike Grimes, PC. 2000 S. Mays St., Suite 302 Round Rock, TX 78664-7577 8. John Leseman vs. Muscle Tech—deposition (Hydroxycut, ephedra,) sudden cardiac death,

case settled. (Pennsylvania, 2003) Plaintiff’s counsel: Len Fodera Monheit, Silverman & Fodera 1835 Market St., Suite 2600 Philadephia, PA 19103-2968 EXPERT WITNESS TESTIMONY (cont.)

9. Sayonara Bhattacharya vs. Twin Laboratories, Inc.—deposition, (Ripped Fuel, ischemic

stroke) case settled. (New Jersey, 2003) Plaintiff’s counsel: David Mazie Nagel Rice & Mazie, LLP 103 Eisenhower Parkway Roseland, New Jersey 07068 10. Cheryl Knight vs. Metabolife Inc.—deposition (Metabolife, arrhythmia), case settled

(California, 2004). Plaintiff’s counsel: John Thornton Andrews & Thornton

820 N. Parton, 2nd Fl Santa Ana, CA 92701

11. Marlena Barnett vs. SK Laboratories—expert report (Fastrak, seizure), case settled

(Arkansas, 2004) Plaintiff’s counsel: David Mitchell

Winrock Place Building 2222 Cottondale Lane, Suite 105

Little Rock, AR 72202 12. Wade Daigle vs. Advocare—expert report (Thermo E, hemorrhagic stroke), case settled

(Texas, 2004) Plaintiff’s counsel: Mark Hefter Shields & Rusk 910 Lavaca Austin, TX 78701 13. Maria Figueroa vs. Cytodyne Technologies—expert report and deposition (Xenadrine RFA-1,

ischemic stroke) case settled (New Jersey, 2005) Plaintiff’s counsel: David Mazie Nagel Rice & Mazie, LLP 103 Eisenhower Parkway Roseland, New Jersey 07068 14. Jamie Sloop vs. Cytodyne Technologies—expert report (Xenadrine RFA-1, coronary

dissection), case settled (Missouri, 2005) Plaintiff’s counsel: Jonathan Keiffer Wagstaff and Cartmell LLP 4740 Grand Avenue, Suite 300 Kansas City, MO 64112

15. Douglas Matheny vs. MiniNatural—expert report (MiniNatural, exertional heat stroke), case

settled (Pennsylvania, 2006) Plaintiff’s counsel: Megan Faust Specter, Specter, Evans & Manogue, P.C. 436 7th Ave 26th Fl, Koopers Building Pittsburgh, PA 15219 EXPERT WITNESS TESTIMONY (cont.)

16. Rashidii Wheeler vs. Next Nutrition—deposition (Ultimate Punch, cardiac arrhythmia) case settled (Illinois, 2014) Plaintiff’s counsel: Eric Quandt Scharf, Banks, Marmor, LLC 333 West Wacker Drive, Suite 450 Chicago, IL 60606 17. Jeremy Falcone vs. Union Pacific Railroad—deposition (OxyECA, seizure) case dismissed (Arkansas, 2015) Defense counsel: Scott Tucker Friday, Eldredge & Clark LLP 400 W. Capitol Ave, Suite 2000 Little Rock, AR 72201 BOOKS & BOOK CHAPTERS (Nonscientific) 1. "I Acted from Principle:" The Civil War Diary of William McPheeters, Confederate

Surgeon in the Trans-Mississippi. BJ Gurley and CD Pitcock, eds. (423 pgs) University of Arkansas Press, 2002. (Awarded the 2003 Basil W. Duke Award by the Military Order of the Stars and Bars for best autobiography/biography related to the Civil War).

2. Gurley, Bill J. “The Civil War Journal of Dr. Henry M. Dye: Texas Surgeon in the

District of Arkansas.” In The Earth Reeled and Trees Trembled: Civil War Arkansas, 1863-1864. Mark Christ, ed., The Old Statehouse Museum, 2007.

3. Gurley BJ and Pitcock CD. "I Acted from Principle:" The Civil War Diary of William

McPheeters, Confederate Surgeon in the Trans-Mississippi in A Rough Business: Fighting the Civil War in Missouri (William G. Piston ed.) The State Historical Society of Missouri Press (Columbia, MO) 2012.

4. Gurley, Bill J. “Mosby M. Parsons: Missouri’s Forgotten Brigadier.” In Confederate

Generals in the Trans-Mississippi. Lawrence Hewitt, ed., University of Tennessee Press (Knoxville, TN) 2013.

5. Gurley Bill J. “Mosby M. Parsons: Major General, Murder Victim.” In Confederate

Generals in the Trans-Mississippi. Lawrence Hewitt, ed., University of Tennessee Press (Knoxville, TN) 2015.

6. Gurley Bill J. Foreward to Villainous Compounds: Chemical Weapons and the

American Civil War by Guy Hasegawa. Southern Illinois Press (Carbondale, IL) 2015. PUBLICATIONS (Nonscientific) 1. Gurley BJ. “A Season of Redemption.” North South Trader’s Civil War. 1991; 15

(4):28-33. 2. Pitcock CD and Gurley BJ. "I Acted from Principle": William Marcellus McPheeters,

Confederate Surgeon. Missouri Historical Review 89: 384-405,1995. PUBLICATIONS (Nonscientific) cont.

3. Gurley BJ. “Hart Attack: An Unlisted Trans-Mississippi Artillery Projectile.” North

South Trader’s Civil War. 1997; 25 (2):60-61. 4. Brainard M and Gurley BJ. “War in the West Yields Rare Bullets II.” North South

Trader’s Civil War. 2013; 37 (4):26-30. 5. Gurley BJ. "Chasing Missourians in Arkansas." North South Trader’s Civil War. 2016;

40 (1):40-49. INVITED PRESENTATIONS AND LECTURES (Nonscientific) 1. The Civil War in Arkansas. Given as part of the UAMS Division of Medical Humanities

enrichment elective series entitled "The American Civil War: Crusade or Revolution", University of Arkansas for Medical Sciences, September 23, 1993.

2. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon.

37th Missouri Conference on History, Jefferson City, Missouri, April 13, 1995. 3. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon in

the Trans-Mississippi Theatre. American Osler Society, San Francisco, California, April 26, 1996.

4. Missouri’s Confederate Infantry Brigades in the Trans-Mississippi Department. Pine

Bluff Civil War Round Table, Pine Bluff, Arkansas, October 30, 1996. 5. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon in

the Trans-Mississippi Theatre. History of Medicine Associates, Little Rock, Arkansas , September 17, 1998.

6. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon in

the Trans-Mississippi Theatre. National Museum of Civil War Medicine ( 7th Annual Meeting), Pickwick Landing, TN, August 8, 1999.

7. "I acted from principle:" William Marcellus McPheeters, M.D., Confederate Surgeon in

the Trans-Mississippi Theatre. “War West of the River: A Seminar on the Civil War in the Trans-Mississippi Theater,” Wilson’s Creek National Battlefield, Springfield, MO, April 1, 2000.

8. “Gunpowder, lard, and kerosene;” Civil War Medicine in the Trans-Mississippi. Invited

talk at a special Civil War symposium entitled “As Much as Humanity can Stand:” The 140th Anniversary of the Little Rock Campaign, Old Statehouse Museum, Little Rock, AR, August 23, 2003.

9. Keynote address for reinterrment ceremony of the “Fagan Six”—reburial of the remains

of six Confederate soldiers discovered in November 2002 who had been killed at the Battle of Helena, AR (July 4, 1863). Helena, AR., March 20, 2004.

10. Yankee Bullets, Rebel Blood: The remarkable journal of Dr. Henry M. Dye, Texas

surgeon in the Civil War. UAMS College of Medicine, History of Medicine Lecture, Little Rock, AR, February 22, 2006.

INVITED PRESENTATIONS AND LECTURES (Nonscientific) cont.

11. Yankee Bullets, Rebel Blood: The remarkable journal of Dr. Henry M. Dye, Texas

surgeon in the Civil War. 13th Annual Meeting of the Society of Civil War Surgeons, Chattanooga, TN, March 25, 2006.

12. “I Acted From Principle”: The Civil War saga of Dr. William McPheeters, Confederate

surgeon in the Trans-Mississippi. 14th Annual Meeting of the Society of Civil War Surgeons, St. Louis, MO, March 24, 2007.


surgeon in the Trans-Mississippi. Pulaski County Historical Society, Little Rock, AR, September 9, 2007.

14. “I Really ‘Dig’ History:” Excavated artifacts of the Civil War in Arkansas and an

introduction to Confederate flags. Christ the King Middle School, 8th grade history classes. Little Rock, AR, October 31, 2007


surgeon in the Trans-Mississippi. St. Louis Civil War Roundtable, St. Louis, MO, March 26, 2008.

16. Yankee Bullets, Rebel Blood: A glimpse at Confederate medical care in the Trans-

Mississippi through the illustrated casebook of Dr. Henry M. Dye. Civil War Roundtable of the Ozarks Seminar, “Beyond Campaigns and Commanders,” Springfield, MO, October 10, 2009.

17. Confederate Grizzly: General Mosby M. Parsons and his Missouri Division. Red River

Civil War Roundtable, Pineville, LA, March 4, 2010. 18. Confederate Grizzly: General Mosby M. Parsons and his Missouri Division. Civil War

Roundtable of Arkansas, Little Rock, AR, August 24, 2010. 19. Civil War Sesquicentennial Exhibits at the Old State House Museum. Arkansas

Museums Association, Little Rock, AR, March 30, 2011 20. Confederate Grizzly: General Mosby M. Parsons and his Missouri Division. White

County Civil War Roundtable, Searcy, AR, November 3, 2011. 21. How and why we have commemorated the Civil War in the past: an emphasis on

Arkansas. Old State House Museum’s Annual Civil War Seminar (Why Commemorate the Civil War?), Little Rock, January 28, 2012.


surgeon in the Trans-Mississippi. Red River Heritage Symposium, Washington, AR, July 28, 2012.

23. Yankee Bullets, Rebel Blood: A glimpse at Confederate medical care in the Trans-

Mississippi through the illustrated casebook of Dr. Henry M. Dye. Arkansas History Commission Symposium, “Health Care in Arkansas History,” Little Rock, AR, June 22, 2013.

INVITED PRESENTATIONS AND LECTURES (Nonscientific) cont.

24. Northern Bullets, Southern Blood: The remarkable medical casebook of Dr. Henry M.

Dye, Confederate surgeon in the Trans-Mississippi. Red River Heritage Symposium, Washington, AR, July 26, 2014.


surgeon in the Trans-Mississippi. Civil War Roundtable of the Delta, Helena, AR, August 11, 2014.

26. Northern Bullets, Southern Blood: The remarkable medical casebook of Dr. Henry M.

Dye, Confederate surgeon in the Trans-Mississippi. Grand Prairie Civil War Roundtable, Lonoke, AR, August 11, 2015.

27. Confederate Grizzlies: General Mosby M. Parsons and his Missouri Division. John T.

Coffee SCV Camp #1934, Osceola, MO, August 20, 2016. 28. Confederate Grizzlies: General Mosby M. Parsons and his Missouri Division. Mosby M.

Parsons SCV Camp #718, Jefferson City, MO, December 8, 2016. MEDIA QUOTES & APPEARANCES 1. Appearance on WCBV TV Boston, MA, November 1997 regarding Ephedra dietary

supplements. 2. Appearance on CNN, (national television broadcast). August 4, 1999 regarding

Ephedra dietary supplements. 3. Quoted in Newsweek (Special Edition) Spring/Summer 1999, “Making Calories Count.” 4. Quoted in New York Times June 17, 1999, “Weight loss the herbal way: no natural

silver bullet.” 5. Quoted in New York Times, October 12, 1999, “Side Effects Raise Flag on Dangers

of Ephedra” 6. Quoted in Shape Magazine, January 2000, “Weight Loss for Sale,” regarding Ephedra

dietary supplements. 7. Quoted in Natural Foods Merchandiser, March 2000, “Ephedra: questions, answers

and alternatives.” 8. Quoted in San Francisco Chronicle, March 6, 2000, “Diet energy pill is sometimes

deadly.” 9. Quoted and study cited in Washington Post, March 25, 2000, “Natural Medicines.” 10. Quoted in SELF Magazine, April 2000, “Herbal Enemy #1: The Dangerous

Supplement You May Already be Taking.” 11. Study cited by Associated Press news service, April 17,2000. “Concerns raised about

ephedra.” 12. Study cited on Excite website April 17, 2000. “Concerns raised about ephedra.” 13. Study cited on USAToday website April 17, 2000. “Ephedra’s risks not clearly

defined.” 14. Quoted and study cited on MSNBC website, April 17, 2000. “Herbal supplement under

attack: Study finds ephedra’s doses, ingredients post health risks.” 15. Study cited on Associated Press website (www.associatedpress.com) April 17, 2000.

“Concerns raised about ephedra.” 16. Study cited on YahooNews website April 17, 2000. “Ephedra’s risks not clearly

defined.” MEDIA QUOTES & APPEARANCES (cont.)

17. Appearance on Dateline NBC (national television broadcast). April 18, 2000, “How safe is ephedra.”

18. Quoted and study cited on MSNBC website,April 18, 2000, “How safe is ephedrine.” 19. Quoted on ABC News website, April 18, 2000. “Figuring out ephedra.” 20. Study cited on MSNBC News (national broadcast) April 18, 2000. “Herbal supplement

under attack.” 21. Study cited on Intelihealth website, April 18, 2000. “Concerns raised about ephedra.” 22. Appearance on KCSN radio (88.5 FM Northridge, CA) on April 18, 2000 regarding

ephedra dietary supplements and the results of a forthcoming study in published in AJHSP.

23. Study cited on CNN News website, April 18, 2000. “Concerns about ephedra–but for whom.”

24. Quoted and study cited on HealthScout website (www.healthscout.com) April 18, 2000, “Naturally confusing.”

25. Quoted and study cited in Food Labeling News (Vol. 8, No. 28, pg 10), April 19, 2000. “Study finds label discrepancies among ephedra-containing supplement products.”

26. Quoted in Washington Post, April 20, 2000. “Woman using herbal aid has stroke.” 27. Appearance on Fox News Channel (national television broadcast). April 20, 2000

regarding quality control of herbal dietary supplements. 28. Quoted and study cited on FoxNews website, April 20, 2000. “Ephedra labels often

misleading.” 29. Quoted on Reuters Health website in a feature entitled “Ephedra labels often

misleading.” April 20, 2000. 30. Quoted on WebMD website, April 20, 2000. “Diet supplement labels don’t match

ephedra amounts.” 31. Quoted on website. April 20, 2000. “Ephedra labels often misleading.” 32. Quoted in St. Paul/Minneapolis Pioneer Press. April 22, 2000. “Dietary danger.” 33. Quoted on LA Times website, April 24, 2000. “Some types of ephedra can be

dangerous.” 34. Study cited in Food Chemical News (Vol. 42, No. 10, pg. 27) April 24, 2000. “ A study

that tested 20 dietary supplements containing ephedra.” 35. Quoted and study cited in the Chicago Tribune, April 27, 2000. “Ephedra product

labels often inaccurate study says.” 36. Quoted on Health Scout website. April 27, 2000. “Quality: Is it job 1 for ephedra

manufacturers?” and “Concern heightens over caffeine content in ephedra.” 37. Appearance on Fox News Channel affiliate in Greensboro, NC concerning ephedra

dietary supplements (regional broadcast), April 28, 2000. 38. Study cited in Nutraceuticals International, May 1, 2000. “Quality problems with

ephedra products contribute to safety concerns.” 39. Quoted in Washington Post. May 2, 2000. “Findings of fact: A reality check on product

claims.” 40. Study cited in New York Times. May 2, 2000. “Standards; when the label doesn’t

measure up.” 41. Study cited in U.S. News & World Report. May 5, 2000. “Herbs and prescriptions can

make a risky mixture.” 42. Quoted in Business Week. May 8, 2000. “Dangerous cocktail: herbals and drugs.” 43. Study cited in The Tan Sheet, May 8, 2000. “Ephedra study.” 44. Quoted and study cited in the St. Petersbug Times, May 15, 2000. “Parents ask if

herb is a killer.” 45. Quoted and study cited in The Houston Chronicle, May 21, 2000. “FDA links death to

herbal stimulant.” MEDIA QUOTES & APPEARANCES (cont.)

46. Quoted and study cited in The Cleveland Plain Dealer, May 22, 2000. “Herbal diet product suspected in death.”

47. Quoted in Washington Post. May 23, 2000. “Ephedra: The adventure continues.” 48. Quoted and study cited on CBS News Healthwatch website. “Herb/drug interactions:

sometimes dangerous.” May 2000. 49. Quoted and study cited in San Francisco Chronicle. June 2, 2000. “Herb Remedies:

Panacea or Problem?” 50. Quoted and study cited in Salon Magazine. June 6, 2000. “Swallowing ephedra.” 51. Quoted and study cited on CBS News Healthwatch website. “Supplement labels, they

are a-changing.” June 2000. 52. Quoted and study cited on CBS News Healthwatch website. “Herbal fraud: let the

buyer beware.” June 2000. 53. Study cited in Washington Post.June 18, 2000 “Diet Supplement Marketers Target

Kids.” 54. Appearance on MSNBC Homepage (national television broadcast). June 29, 2000,

regarding adverse effects of Ephedra-containing dietary supplements. 55. Quoted in Retail Pharmacy News. June 2000 issue “What’s in a (Ephedra) Label?” 56. Quoted in Retail Pharmacy News. July, 2000 issue. “Controversial study reignites

concerns about dietary supplements and ephedra.” 57. Quoted in Memphis Commercial Appeal, July 3, 2000 “Fat-burners under fire: dietary

supplements may melt the pounds away but weigh you down with other health concerns.”

58. Quoted on MyLifePath website, July 8, 2000, “Bad Business, Part II: Ephedra Supplements.”

59. Study cited in Washington Post, July 23, 2000, “A ‘neutral’ comment, a company’s tough reaction.”

60. Study cited in Investor’s Business Daily, August 1, 2000. “Herbal supplements: Don’t trust all labels.”

61. Quoted and study cited in Fitness Magazine, September 2000 (pg. 86.) “Savvy shopper: another strike against ephedra.”

62. Quoted in Women’s Wisdom, Rodale Press, 2000. Sharon Faelten (ed.), “Natural weight loss pills to avoid.” pp204-205.

63. Quoted and study cited in Reader’s Digest, October 2000, “Herbal Enemy No. 1.” pp 126-131.

64. Appearance on KTHV Channel 11 (statewide broadcast in Arkansas). September 27, 2000.

65. Quoted in The Orlando Sentinel, October 23, 2000, “Ephedra exposed.” 66. Appearance on KSPR Channel 33(statewide broadcast in Missouri). Scheduled for

November , 2000. 67. Quoted on HealthScout website (www.healthscout.com) November 2, 2000, “St.

John’s wort may interfere with medicines.” 68. Appearance on CNN, (national television broadcast). November 6, 2000 regarding

Ephedra dietary supplements. 69. Quoted in The Philadelphia Inquirer, November 13, 2000, “What’s behind latest drug

warnings.” 70. Quoted and study cited in the Arkansas Democrat-Gazette; December 4, 2000,

“Worrisome worts.” 71. Quoted in Good Housekeeping, January 2001, “What’s your doctor selling?” pp 53-64. 72. Quoted and study cited in cover story for U.S. News & World Report, “The Risks of

Natural Cures,” February 12, 2001. 73. Quoted in feature article for Consumer Reports magazine, June 2001, “Sports-

supplement dangers,” pp. 40-42. MEDIA QUOTES & APPEARANCES (cont.)

74. Quoted and study cited in Health magazine, July/August, 2001, “The Scoop on Ephedra,” pp. 66-72.

75. Quoted and study cited in New York Daily News, July 15, 2001, “Supplements, Part I: Bitter Pills Swallow Sports.”

76. Quoted and study cited in New York Daily News, July 16, 2001, “Supplements, Part II: Speed Demons, Ephedra striking users fast and furiously.”

77. Quoted in Los Angeles Times, August 11, 2001, “Player Wheeler Used Supplement.” 78. Quoted in Los Angeles Times, August 11, 2001, “Substances are Easily Obtained:

Ephedra, common in over-the-counter dietary supplements, has been linked to 80 deaths.”

79. Quoted in New York Times, August 13, 2001, “Breast enlargement ads mostly rejected.”

80. Appearance on CBS radio (New York), August 13, 2001. 81. Appearance on CBS radio (Los Angeles), August 13, 2001 82. Quoted on WebMDHealth website, August 14, 2001, “Energy Drinks: Boost or Bust.” 83. Quoted in Chicago Tribune, August 20, 2001, “Supplements lure athletes, skirt FDA.” 84. Quoted in Los Angeles Times, August 27, 2001, “Risks of ephedra usage in spotlight.” 85. Featured in Arkansas Times, October 5, 2001, “Rooting out the dangers of herbal

medicines.” 86. Appearance on ABC’s Good Morning America, November 22, 2001. 87. Appearance on WCCO radio (Minneapolis, MN), November 26, 2001. Program

devoted to ephedra supplements. 88. Quoted in U.S. News & World Report, January 21, 2002, “Danger at the gym.” 89. Appearance on “Here’s To Your Health”, KUAR FM 89, Little Rock, AR, Februaury 4,

2002. 90. Appearance on National Public Radio (NPR), “Herbal dietary supplements and drug

interactions.” Week of February 4, 2002. 91. Quoted in Arkansas Democrat Gazette, March 11, 2002, “The Perfect-Pill Pitch.” 92. Quoted in Mobile Register, May 23, 2002, “Expert warns of dangers tied to herbal

supplements.” 93. Appearance on WMPI Channel 15 (television broadcast in Mobile, AL and Pensacola,

FL), May 30, 2002. 94. Quoted in Men’s Journal, July 2002 issue, “This is Todd Weger’s Brain on Ephedra.” 95. Quoted in People Magazine, July 1, 2002, “A Deadly Diet Aid.” 96. Quoted in San Francisco Chronicle, July 21, 2002, “New diet pill – new health risks.” 97. Appearance on KTHV Channel 11 (statewide television broadcast in Arkansas),

August 2, 2002. Ephedra-containing dietary supplements and risk of hyperthermia. 98. Appearance on KARK Channel 4 (statewide television broadcast in Arkansas), August

15, 2002. Ephedra-containing dietary supplements and risk of hyperthermia. 99. Quoted in The Chicago Tribune, August 16, 2002, “U.S. Targets Ephedra Seller.” 100. Appearance on KTHV Channel 11 (statewide television broadcast in Arkansas),

August 16, 2002, Risks associated with the ephedra-containing dietary supplement, Metabolife.

101. Appearance on KTHV Channel 11 (statewide television broadcast in Arkansas), August 26, 2002, “Medical Monday: Dangers of Ephedra-containing Dietary Supplements.”

102. Quoted and study cited in Los Angeles Times, September 2, 2002, “A Tug of War in a Larger Battle.”

103. Quoted and study cited in Woman’s Day magazine, September 17, 2002 issue, “Are herbal remedies safe?”

MEDIA QUOTES & APPEARANCES (cont.) 104. Appearance on KARK Channel 4 (statewide television broadcast in Arkansas)

September 17, 2002, segment entitled “Arkansas’ Own” devoted to the book “I Acted From Principle:” The Civil War Diary of Dr. William M. McPheeters, Confederate Surgeon in the Trans-Mississippi.

105. Appearance on KATV Channel 7 (statewide television broadcast in Arkansas) October 8, 2002. “Dangers of Yellow Jackets: an ephedra-containing dietary supplement.”

106. Quoted and study cited in Body & Soul magazine, Winter 2002 issue, “The Diet-Pill Dielmma.”

107. Quoted in the Los Angeles Times, December 9, 2002, “Trouble with Ephedra.” 108. Appearance on KARN Radio (920 AM), Little Rock, AR, January 9, 2003, “The Truth

About Over-The-Counter Weight Loss Products.” 109. Quoted in Glamour magazine, February 2003 issue, “Are these diet pills deadly.” 110. Appearance on MSNBC “The Nachman Report” (nation-wide television broadcast),

February 18, 2003. Discussion of Ephedra supplements and heat-related illness. 111. Appearance on ESPN radio (national broadcast), February 18, 2003. Discussion of

ephedra supplements and their possible link to the death of Baltimore Orioles’s pitcher, Steve Bechler.

112. Appearance on WCCO Radio, Minneapolis, MN, February 19, 2003. Discussion of ephedra-containing supplements and heat-related illness.

113. Appearance of KHTB Channel 29(television broadcast in Northwest Arkansas). Ephedra supplements and their contribution to heat related illness.

114. Quoted in the Chicago Sun-Times, February 20,2003. “Supplementing the truth.” 115. Quoted in The Washington Times, February 20, 2003. “Is ephedrine on way out?” 116. Quoted in The New York Daily News, February 20, 2003. “More ‘Orange’ juice.” 117. Appearance on WCCO Radio, Minneapolis, MN, February 25, 2003. Safety and

efficacy issues regarding dietary supplements. 118. Quoted and study cited on US News.com (website for U.S. News & World Report

Magazine) March 6, 2003. “Ephedra danger at the gym.” 119. Quoted in the New York Times, March 8, 2003, “F.D.A. to put new rules on dietary

supplements.” 120. Quoted in the Los Angeles Times, March 19, 2003, “U.S. sales of products with

ephedra slipping amid rising concern.” 121. Quoted in the Mother Jones magazine, May/June, 2003, “Teen Herbicide: Dietary

supplements can be deadly. So why are they being marketed to kids.” 122. Appearance on KARK Channel 4 (statewide television broadcast in Arkansas) April

24, 2003, segment discussing the dangers of the ephedra supplement Xenadrine RFA-1.

123. Quoted in Minneapolis-St. Paul Star Tribune, April 29, 2003, “Ephedra-free products loaded with new herbs of concern.”

124. Appearance on B98.5 (local FM radio station), May 14, 2003, Interview discussing the dangers of ephedra-containing weight-loss supplements.

125. Appearance on KTHV Channel 11 (statewide television broadcast in Arkansas), May 21, 2003, Story focusing on the ban of ephedra-containing supplements in Illinois.

126. Quoted in The Wall Street Journal, June 4, 2003, “As ephedra fades, consumers snap up alternatives.”

127. Quoted in and article cited in Science News, June 7, 2003 (Vol. 163, pp.359-361) “Herbal Lottery.”

128. Appearance on Good Morning Arkansas, June 9, 2003 (KATV Channel 7, statewide television broadcast). Discussion of ephedra and ephedra-free supplements.

129. Quoted and study cited in SELF magazine, July 2003 issue, “The new diet danger.” 130. Appearance on ABC radio program, “The Satellite Sisters” discussing dietary

supplements (nationwide broadcast). August 2, 2003.

MEDIA QUOTES & APPEARANCES (cont.) 131. Quoted in The Arizona Republic, August 7, 2003, “Stimulants given to migrants may

play role in death.” 132. Quoted in the Chicago Tribune, September 28, 2003, “We spy a gimmick for drinkers.” 133. Appearance on WCCO radio (The Pat Miles Show), Minneapolis, MN, October 13,

2003. Discussion on the effectiveness of alternative weight loss products. 134. Quoted in Arkansas Democrat Gazette, December 31, 2003 “Ephedra-laced

supplements face ban.” 135. Interviewed for Newsweek Magazine, December 30, 2003 136. Quoted in Prevention magazine, January 2004, “Beware ephedra substitutes.” 137. Quoted in Consumer Reports, January 2004, “Ephedra-free, but is it safe.” 138. Appearance on KTHV Channel 11, (Arkansas statewide television broadcast)

December 30, 2003. regarding the FDA ban on ephedra supplements. 139. Appearance on KARK Channel 4 (Arkansas statewide television broadcast) January

3, 2004, segment discussing the FDA ban on ephedra-containing dietary supplements and the safety and efficacy of ephedra-free supplements.

140. Study quoted in USA Today, January 5, 2004, “Law lets risky stimulants take ephedra’s place.

141. Quoted in Business Week, January 13, 2004, “Commentary: Ephedra: One down, one more to go.”

142. Appearance on KRTR radio, January 19, 2004, Portland OR, discussing the dangers of ephedra supplements.

143. Quoted in USA Today, February 17, 2004, “Grief for son fills Bechlers’ days, nights. 144. Quoted in the Arkansas Democrat Gazette, March 12, 2004,” Dangers of sports

supplements.” 145. Quoted in the Pocahontas Star Herald, March 25, 2004. “Reburial service held for six

Confederate soldiers killed at Battle of Helena.” 146. Appearance on KARN radio, Little Rock, AR, April 1, 2004, Discussion of Ephedra

supplements. 147. Appearance on NPR radio, April 8, 2004, Discussion of Ephedra and wephedra-free

dietary supplements. 148. Appearance on KARN radio, Little Rock, AR, April 8, 2004, Discussion of Ephedra and

ephedra-free dietary supplements. 149. Quoted in The Oprah Magazine, “Another bitter (diet) pill.” April, 2004. 150. Appearance on KTHV Channel 11, (Arkansas statewide television broadcast) April 12,

2004, regarding the FDA ban on ephedra supplements. 151. Appearance on KARK Channel 4, (Arkansas statewide television broadcast) April 12,

2004, regarding the FDA ban on ephedra supplements. 152. Appearance on KATV Channel 7, Arkansas (statewide television broadcast) April 12,

2004, regarding the FDA ban on ephedra supplements. 153. Appearance on KLRT Channel 16, Arkansas television broadcast) April 12, 2004,

regarding the FDA ban on ephedra supplements 154. Quoted in LA Times, April 12, 2004, “A question of fitness: Gov. Schwarzeneggers’s

ties to bodybuilding magazines raise issues of appropriateness. Other say he’s promoting exercise.”

155. Quoted in Consumer Reports, May 2004, “Dangerous Supplements Still at Large.” 156. Study cited in The Wall Street Journal, June 22, 2004 “The risks of mixing drugs and

herbs.” 157. Quoted in the Los Angeles Times, July 19, 2004, “Ephedra-free weight-loss

supplements scrutinized.” 158. Appearance on KATV Channel 7, Arkansas television broadcast) August27, 2004,

“Arkansas’ Bright Ideas” (segment on OmniBalm cream). MEDIA QUOTES & APPEARANCES (cont.)

159. Appearance on KATV Channel 7,, Arkansas television broadcast) “Good Morning Arkansas,” September 9, 2004. (segment discussed safety and efficacy of “ephedra-free” dietary supplements.)

160. Appearance on KWGN Channel 2, (Colorado television broadcast) February 25, 2005. Feature discussing the safety and efficacy of weight loss products containing bitter orange.

161. Quoted in The Mercury News, March 31, 2005, “Governor denies endorsing disputed diet supplements.”

162. Appearance on KLRT Channel 16, (Arkansas television broadcast) November 21, 2005. Feature discussing the efficacy and safety of “Ephedra-free” weight-loss supplements.

163. Quoted in New York Daily News, December 25, 2005, “Beating the Heat. Thanks to ’94 law, supplements still poppin.’”

164. Appearance on KLRT Channel 16, (Arkansas television broadcast), Feature discussing the fraudulent nature of many dietary supplements, February 29, 2006.

165. Appearance on KLRT Channel 16, (Arkansas television broadcast), Feature discussing the dangers of certain botanical supplements purchased over the internet, March 1, 2006.

166. Quoted in Science News, May 13, 2006. “Sleight of Herb: Black cohosh mislabeled in medicinal products.”

167. Appearance on KARN 102.9 FM Little Rock radio broadcast discussing the health concerns of caffeine-containing “Energy drinks.” November 6, 2006.

168. Appearance on KTHV Channel 11 (Akansas televsion broadcast) Feature discussing education, technology, and high-tech job opportunities in Arkansas. December 5, 2006.

169. Quoted in the Fort Worth Star-Telegram newspaper, “Grand Prairie charity was paid to funnel funds,” December 23, 2006.

170. Appearance on KARK Channel 4 (Arkansas television broadcast) Feature discussing the dangers of combining stressful exercise and caffeine-containing “energy drinks” in very hot weather. August 29, 2007.

171. Appearance on KTHV Channel 11 (Arkansas television broadcast) Feature discussing the availability and validity of anabolic steroids purchased over the internet. October 18, 2007.

172. Appearance on KTHV Channel 11 (Arkansas television broadcast) Feature discussing caffeine-containing “energy drinks”, their uses and abuses by teens and young adults. February 19, 2008.

173. Quoted in Consumer Reports on Health, September 2008. “Herbs that change drug effects.”

174. Appearance on KARK Channel 4 (Arkansas television broadcast) Feature discussing an FDA warning of weight-loss supplements available on the internet adulterated with various conventional medications. December 23, 2008.

175. Quoted in Military Officer, April 2009, “The right alternative?” 176. Appearance on KARK Channel 4 (Arkansas television broadcast) Feature discussing

the safety and efficacy of “anti-energy drinks.” September 30, 2009. 177. Quoted in New York Daily News, December 2, 2009. “United States Anti-Doping

Agency teams up with NFL, MLB to curb steroid-spiked supplements.” 178. Quoted in Medical News of Arkansas, December 2009. “Ark Lab Leads World in

Supplement-Rx Research.” 179. Podcast for the American Society of Clinical Pharmacology and Therapeutics on the

subject of dietary research, safety and efficacy. January 14, 2010. 180. Quoted in Consumer Reports, March 2010, “Legal Ephedra?” 181. Appearance on KATV Channel 7, February 16, 2011. Feature discussing the safety of

“energy drinks” in children.

MEDIA QUOTES & APPEARANCES (cont.) 182. Appearance on KATV Channel 7, May 8, 2011. Feature discussing Old State House

Museum’s Civil War Sesquicentennial Exhibit, “An Enduring Union.” 183. Quoted in Arkansas Democrat Gazette, May 15, 2011. Feature article on the one

hundredth anniversary of the 1911 United Confederate Veterans reunion held in Little Rock.

184. Quoted on website MedPage Today (http://www.medpagetoday.com) July 25, 2011. Antibiotics trump cranberries for bladder infections.

185. Quoted on website MedicalNewsToday (http://medicalnewstoday.com) July 25, 2011. Antibiotic beats cranberry capsules in preventing recurrent urinary tract infections - antibiotic resistance a concern.

186. Quoted on website FirstScience.com (http://firstscience.com) July 25, 2011. Antibiotic appears more effective than cranberry capsules for preventing urinary tract infections.

186. Quoted on website ScienceDaily (http://sciencedaily.com) July 26, 2011. Antibiotic appears more effective than cranberry capsules for preventing urinary tract infections.

187. Quoted on website MedicalResearch.com (http://medicalresearch.com) July 26, 2011. Antibiotic appears more effective than cranberry capsules for preventing urinary tract infections.

188. Appearance on KATV Channel 7, February 16, 2012. Feature discussing the safety of “energy drinks” in children, teenagers, and adults.

189. Appearance on KKSP Radio, November 1, 2012. Live interview regarding the safety of energy drinks in adolescents and young athletes.

190. Appearance on KATV Channel 7, December 20, 2012. Feature discussing the safety of “energy drinks” in children.

191. Quoted in NUTRA ingredients-usa.com newsletter. July 12, 2013. Article entitled “Unknowns related to bioavailability enhancers troubles pharmacy researcher.”

192. Appearance on KARN 102.9 radio, November 27, 2013. Live interview discussing Omnibalm™–a new diabetic foot care product invented in Arkansas.”

193. Appearance on KTHV Channel 11, December 3, 2013. Feature discussing UAMS-development of Omnibalm™ Daily Foot Therapy and its use in diabetic foot care.

194. Quoted in American Botanical Council press release, January 8, 2014. Kava may help prevent lung cancer in smokers say university researcher: preliminary study in mice suggests possible lung cancer preventative effect of South Pacific herb.

195. Featured in NIH Record. “NCCAM lecturer explains herb-drug interactions.” Vol. LXVI. No. 8, April 11, 2014. 196. Appearance on KATV Channel 7, March 30, 2015. Feature discussing results of a clinical study of Omnibalm™ Daily Foot Therapy conducted in Arkansas and the product’s use in preventing recurrent diabetic foot ulcers.

UAMS | Arkansas - Gurley Curriculum Vitae 2016 · 2017-07-25 · Research Center, Baton Rouge, LA....

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