Typhus
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Transcript of Typhus
Typhus
Dr. Richin Koshy
Basic details
• 46 yr old female came wih complaints of high fever, joint pain and truncal rashes for 2 week.
• Consulted Rural PHC
• Analgesics taken as and when needed
• Not responding to medications
Chief Complaints
• Headache
• Fever
• Rash
DIFFRENTIAL DIAGNOSIS – Fever with a rash
• Measles
• Rubella h/o - Immunisation
• Lyme disease
• Leptospirosis
• Typhoid Fever
• Acute Retroviral Syndrome
• Roseola – HHV 6
• Louse-borne Typhus
• Murine Typhus
• Secondary Syphilis
• Meningococcemia
INVESTIGATION ADVISED
• CBC
• WIDAL
• ESR
• CRP
• HIV antibody and viral load
• Antibody Orientia tsutsu gamushi
Diagnosis
• Typhus
TREATMENT GIVEN
Treatment for all rickettsial diseases and vector-borne illness is doxycycline.
REPORT
• R. typhi is carried usually in rats and transmitted to humans from feces of fleas.
• R. prowazekii is transmitted from the feces of lice.
• Symptoms of typhus include an incubation of 6-15 days. After 1-3 weeks post bite an infected individual presents with sudden chills, high fever, and headache. 5-9 days after onset a maculopapularrash appears on the trunk and spreads to extremities, usually sparing the face, palms, and soles.
• Diagnosis can be made via serology using the indirect fluorescent antibody (IFA) test.
• Rickettsia are Weil-Felix positive
• THANK YOU.