TUBERCULOSIS IN ORTHOPAEDICS - Kamineni Institute … · 2015-12-03 · Tuberculosis can affect any...
Transcript of TUBERCULOSIS IN ORTHOPAEDICS - Kamineni Institute … · 2015-12-03 · Tuberculosis can affect any...
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TUBERCULOSIS IN
ORTHOPAEDICS
Dr.Rohit
Final year PG
Orthopaedics
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• TB HIP
• TB OF SPINE
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BONE & JOINT TUBERCULOSIS
• Tuberculosis can affect any bone in the body from cervical spine to foot bones.
• It can also affect the synovial sheath of the tendons (tenosynovitis)
• The incidence of skeletal tuberculosis is 1 – 4%.
• Skeletal tuberculosis is always secondary to a primary focus elsewhere in the body and occurs by heamatogenous spread or by direct extension.
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TB HIP
• 15% of skeletal tuberculosis.
• The initial focus may start in the;
1. Acetabular roof
2. Greater trochanter
3. Femoral epiphysis
4.Synovial membrane
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• In the hip joint, head and
neck are intracapsular so
a bony lesion invades
the joint early.
• May become so
extensive that
pathological dislocation
of joint may occur.
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Pathogenesis
Primary focus
heamatogenous spread / by direct extension
Joint
Synovial membrane
Tuberculous synovitis
Synovial effusion
Articular cartilage damage
Subchondral bone erosion
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STAGES OF TB HIP
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STAGE I
• Stage of synovitis.
• There is effusion into the joint
which demands the hip to be
in a position of maximum
capacity i.e. flexion, abduction
and external rotation.
• Stage of apparent lengthening.
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STAGE II
• Stage of arthitis.
• Articular cartilage is damaged.
• Leads to spasm of powerful muscles around the hip.
• Flexors and Adductors are the stronger muscles.
• Thus the hip goes into flexion, adduction and internal rotation.
• Stage of apparent shortening.
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STAGE III
• Stage of erosion.
• Cartilage gets destroyed.
• Head and acetabulum gets eroded.
• Pathological subluxation or dislocation occurs.
• Hip is in flexion, adduction and internal rotation.
• True shortening of the limb.
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Clinical picture
General features
• Common in first 3 decades of life.
• Fever
• Loss of apetite
• Loss of weight
• Mono articular involvement
Specific features
• Pain (insidious onset)
• Local raise of temperature
• Limitation of movements
• Night cries
• Muscle wasting
• Regional lymph node involvement
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X-RAY FINDINGS
• Soft tissue swelling
• Localised osteoporosis
• Haziness of articular margins
• Decreased joint space
• In advanced cases;
Collapse of the bone,
Sub luxation/dislocation of joint.
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MRI
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PROGNOSIS
• Depends upon the stage of the disease.
• Early disease (synovitis & early arthritis) may
heal leaving a normal / near normal hip.
• Advanced arthritis results in fibrous ankylosis.
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Treatment
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Rest
• Pts. are advised to sleep on a firm bed.
• In active stage of the disease, the joints are
given rest in the functional position.
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Traction
• To correct the
deformity.
• To maintain the limb in
the functional position.
• To hold the inflammed
joint surfaces apart.
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ATT
• ATT should be given for at least a minimum of 1 year and preferably 18 months in some cases.
• Intensive phase; 5-6 months
Isoniazid (5mg/kg)
Rifampicin (10mg/kg)
Flouroquinolones
• Continuation phase; 9-10 months
Isoniazid (5mg/kg)
Pyrazinamide (25mg/kg)
• Prophylactic phase; 3-4months
Isoniazid (5mg/kg)
Ethambutol (15mg/kg)
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OPERATIVE TREATMENT
• It depends upon the stage of the disease &
extent of joint damage.
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• In stage of Synovitis;
Synovectomy & Arthrotomy.
• Stage of Early arthritis;
Synovectomy & Debridement of
loose bodies and granulation tissue.
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In stage of Advanced arthritis
• Arthrodesis
• Girdle stone excission
• Arthroplasty usually done after 6 months after
the start of the ATT.
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Healing of disease
• It can be identified;
• Clinically by disappearance of local symptoms
like pain, warmth, spasm and constitutional
symptoms.
• Radiologically by remineralisation, restoration
of bony outlines and articular margins.
• ESR will come down.
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TB SPINE
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INTRODUCTION
• Most common form of skeletal TB.
• Accounts for 50% of all cases of skeletal TB.
• Neurological complications are the most crippling
complications of spinal TB.
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REGIONAL DISTRIBUTION
Cervical (12%)
Dorsal (42%)
Lumbar (26%)
Sacral (3%)
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Patterns of Vertebral Involvement
Four patterns :
• Paradiscal ( common)
• Central
• Anterior
• Appendical
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PATHOGENESIS
Para discal involvement
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Collapse of vertebrae & Cord compression
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Clinical features
• Back pain
• Stiff spine
• Deformity
• Cold abscess
• Neuro deficit
• Constitutional symptoms
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DEFORMITY
• Knuckle:
Prominence of one spinous process
• Angular Kyphus :
Prominence of two or more spinous processes due to destruction of two or more bodies.
• Gibbus:
Diffuse kyphosis due to involvement of more number of vertebrae.
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COLD ABSCESS
• Pus produced at the site of pathology may stay at the same vertebral level or
• May track down the paths of least resistance along the fascial planes of vessels or nerves and present as a cold abscess in different regions far away from the site of pathology.
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• Cervical and upper
dorsal abscess;
retropharyngeal abscess
posterior mediastinal mass
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• FROM D4 - D 10
LESIONS;
Present on either side of
vertebral body contained in a
thick walled sac leading to a
bird’s nest abscess
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• BELOW D 11 LESIONS
Tracks down along the
psoas sheath & even may
present as a groin
swelling.
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PLAIN RADIOGRAPH
Reduced disc space
Blurred paradiscal margins
Destruction of bodies
Increased Prevertebral soft tissue shadow
Decreased Lordosis
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TUBERCULOUS SPINE WITH
PARAPLEGIA
• Incidence : 10 – 30 %
• Dorsal spine most common
• Motor functions affected before / greater than sensory.
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PATHOLOGY OF TUBERCULOUS
PARAPLEGIA
• Inflammatory Edema :
Vascular stasis , Toxins.
• Extradural Mass :
Tuberculous osteitis of VB & Abscess.
• Bony disorders :
Sequestra , Internal Gibbus
• Infarction of Spinal Cord :
Endarteritis, Periarteritis or thrombosis
• Changes in Spinal Cord :
Thinning (Atrophy), Myelomalacia.
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“EDDON’“ CLA““IFICATION OF
TUBERCULOUS PARAPLEGIA
• GROUP A (EARLY ONSET PARAPLEGIA)
• GROUP B (LATE ONSET PARAPLEGIA)
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TREATMENT
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MIDDLE PATH REGIME
Rationale
All spi e TB ases do ot e ui e su ge y and only those who do not respond to
o se vative easu es should e ope ated
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MIDDLE PATH REGIME
Treatment is on non-operative lines with AKT, rest & spinal braces
1.Rest: in hard bed or plaster of Paris bed( in children)
2.Drugs :
INTENSIVE PHASE-
INH (5mg/Kg) +Rifampicin (10mg/Kg) +ETB (15mg/Kg) + PZA(25mg/Kg) for 6 months
CONTINUATION PHASE-
INH (5mg/Kg) +Rifampicin (10mg/Kg) for next 12 months.
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supportive therapy-
multivitamins,
hematinics if necessary &
high protein diet.
3.Radiographs & ESR: at 3-6 months interval
4.Gradual mobilisation:
with the help of spinal braces
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Indications of surgery :
1. No progressive recovery after a fair trial of
conservative t/t (3-4 wks)
2. Neurological complication develops during
conservative treatment
3. Worsening of Neuro-deficit during t/t
4. Pressure effects (deglutition/respiratory)
5. Advanced cases of neurological involvement
(sphincter disturbances, flaccid paralysis, or
severe flexor spasms)
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OPERATIVE PROCEDURES
• Anterior decompression
• Antero-Lateral decompression
• Posterior decompression
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THANK YOU