Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian...
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![Page 1: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/1.jpg)
Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be
scientifically examined and given a medical diagnosis
by Helen D. Donoghue, Oona Y.-C. Lee, David E. Minnikin, Gurdyal S. Besra, John H. Taylor, and Mark Spigelman
Proceedings BVolume 277(1678):51-56
January 7, 2010
©2010 by The Royal Society
![Page 2: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/2.jpg)
The original appearance of the Granville mummy.
Helen D. Donoghue et al. Proc. R. Soc. B 2010;277:51-56
©2010 by The Royal Society
![Page 3: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/3.jpg)
Demonstration of M. tuberculosis complex DNA in mummy lung sample.
Helen D. Donoghue et al. Proc. R. Soc. B 2010;277:51-56
©2010 by The Royal Society
![Page 4: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/4.jpg)
Detection of M. tuberculosis complex mycolic acid PBA–PFB derivatives by reverse-phase fluorescence HPLC, from the Granville mummy femur and lung samples, in comparison with a
known standard strain of M. tuberculosis.
Helen D. Donoghue et al. Proc. R. Soc. B 2010;277:51-56
©2010 by The Royal Society
![Page 5: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/5.jpg)
Normal-phase HPLC analyses of the collected total mycolates from the reverse-phase separation, from the Granville mummy femur and lung samples, in comparison with a known
standard strain of M. tuberculosis.
Helen D. Donoghue et al. Proc. R. Soc. B 2010;277:51-56
©2010 by The Royal Society
![Page 6: Tuberculosis in Dr Granville's mummy: a molecular re- examination of the earliest known Egyptian mummy to be scientifically examined and given a medical.](https://reader030.fdocuments.in/reader030/viewer/2022032804/56649e4b5503460f94b3f9c8/html5/thumbnails/6.jpg)
Reverse-phase HPLC analyses of the collected fractions from the normal-phase HPLC separation, from the Granville mummy femur and lung samples, in comparison with a known
standard strain of M. tuberculosis.
Helen D. Donoghue et al. Proc. R. Soc. B 2010;277:51-56
©2010 by The Royal Society