Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program.
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Transcript of Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program.
Traditional Medicine and HIV Clinical Pharmacology:
Implementation Research
Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program
Outline
Parirenyatwa Hospital OI clinic support group
Support group – Researcher model Herb-drug clinical study
Parirenyatwa Hospital OI clinic support group
People with common interests and experiences
Safe space to share common concerns, verbalize emotions
Positive reinforcement, emotional support, hope
Learning environment –coping skills, self-help projects, treatment information
Support group Researcher
model born out of the HIV-infected patients’ needs for comprehensive pharmacotherapy and the pharmacologists’ needs to explore pharmacotherapy issues in HIV-Infected patients
mutually beneficial collaboration between support group and researcher
Prevalence of Use of Traditional Medical Systems
Traditional Medicine
Preliminary in vivo studies in animal models typically serve as a basis for clinical trials
Effect of Moringa oleifera (Moringa, Drumstick, Horseradish tree) on the Pharmacokinetics of Efavirenz and Nevirapine in vivo.
Ethical Considerations
To compare the steady-state pharmacokinetics of nevirapine and efavirenz in HIV-positive patients before and after supplementation with Moringa oleifera leaf powder
5 challenging levels of ethical and regulatory approvals (JREC, HSIRB, BRTI- exemption) Medical Control Authority (MCAZ)and national ethics committee (MRCZ)
Acknowledgements
The program is sponsored by the UB-UZ AIDS International Training Research program funded by the Fogarty International Center.