Limitations with Vision for Near, Distance, and Social Activities:

A Comparison Among Three Models of Presbyopia-Correcting

IOLs

Trevor Woodhams, MD

Financial Disclosure:Alcon sponsored the study and provided statistical and presentation support.

Purpose

To evaluate limitations with vision for near, distance, and social activities, as reported by patients with bilateral aspheric apodized diffractive multifocal IOLs (IQ ReSTOR +3.0 D IOLs, Alcon), bilateral aspheric accommodative IOLs (Crystalens AO; Bausch & Lomb), or bilateral spherical accommodative IOLs (Crystalens HD; Bausch & Lomb).

Methods A prospective, patient-masked,

multicenter study › patients with bilateral cataracts› <1.0 D of corneal astigmatism

Randomized to receive implantation of bilateral multifocal IOLs, bilateral AO IOLs, or bilateral HD IOLs

3-mo interim results

Demographics

IOLN-

Value

Mean Age (SD)

Years

Age Range

% Female

IQ ReSTOR +3.0 D IOL 47 63.4 (9.4) 41 to 81 59.6%

Crystalens HD IOL 44 64.0 (7.8) 50 to 79 56.8%

Crystalens AO IOL 41 65.3 (7.5) 50 to 81 63.4%

No significant between-group differences.

Endpoints Evaluated

Preoperatively and at 3 months postoperative, a validated questionnaire (Cataract TyPE) was distributed

Composites scores of questions about various activities were used to assess limitations with uncorrected:› near-vision function (5 questions) › distance-vision function (7 questions)› vision for social activities (5 questions)

Response options ranged from 0 (no limitation) to 4 (extreme limitation), or could be marked as not applicable

Limitations with Uncorrected Vision at Near Distance @ 3-month visit

+3.0 D IOL, N=44

HD IOL, N=37 AO IOL, N=400

1

2

3

4

0.43

1.051.25

Rati

ng

(0

to

4)

Less L

imit

ati

on

Least limitation in near vision activities with the IQ ReSTOR +3.0 D IOL, followed

by HD IOL, then AO IOL.

None

Extreme limitation

*P<.02; IQ ReSTOR +3.0 D IOL had least limitation among IOLs

*

Limitations with Uncorrected Vision at Far Distance @ 3-month visit

+3.0 D IOL, N=44

HD IOL, N=37 AO IOL, N=440

1

2

3

4

0.41

1.05

0.53

Rati

ng

(0

to

4)

Less L

imit

ati

on

None

Extreme limitation

Least limitation in distance vision activities with the IQ ReSTOR +3.0 D, followed by AO

IOL, then HD IOL.

*P=.01; IQ ReSTOR +3.0 D IOL had least limitation among the IOLs

*

Limitations with Uncorrected Vision during Social Activities @ 3-month visit

Going to movies

Visiting with friends

Going to a party

Going out to dinner

Going to a sporting

event

0

1

2

3

4+3.0 D IOL, N=42 HD IOL, N=37 AO IOL, N=42

Rati

ng

(0

to 4

)

Less L

imit

ati

on

None

Extreme limitation

Least limitations in social activities with the IQ ReSTOR +3.0 D IOL, followed by AO IOL,

then HD IOL.

* * *

*P<.05; between-group differences favoring IQ ReSTOR +3.0 D IOL

Conclusions Three months after bilateral implantation of

presbyopia-correcting IOLs, limitations with uncorrected vision for:› Near distance were least for the IQ ReSTOR +3.0 D IOL

group, followed by the HD IOL group, and greatest for the AO IOL group

› Far distance were least for the IQ ReSTOR +3.0 D IOL group, followed by the AO IOL group, and greatest for the HD IOL group

› Social activity were least for the IQ ReSTOR +3.0 D IOL group, followed by the AO IOL group, and greatest for the HD IOL group