Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection

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Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection Abstract Purpose: To evaluate pseudophakic cystoid macular edema (CME) by optical coherence tomography (OCT) and determine the efficacy of intravitreal triamcinolone acetonide injections. Methods: In this nonrandomized retrospective study, 10 eyes of 09 patients with persistent pseudophakic CME were treated with single triamcinolone acetonide injection and were followed up for 6 months . All patients underwent complete ophthalmologic examination including determination of best-corrected visual acuity, slit-lamp examination, tonometry, funduscopy and OCT recorded before and after 10, 20 days and 3 months the injection. Results: Visual acuity and value increased in all patients after intravitreal triamcinolone acetonide injections. OCT showed improvement of the retinal thickness in the macular area. There was no increase of intraocular pressure . Conclusion: Intravitreal triamcinolone acetonide injection is a promising therapeutic tool for chronic pseudophakic edema resistant other medical treatment. However, further study is needed to assess the treatment’s long-term efficacy, its safety, and the need for retreatment. There is no significant difference in the use of acrylic lenses and silicon lens in our results. Gonçalves CA..; Garcia, Marcos A..; Odloak CM. ;Campos, Paloma C.; Boro, Luiz Humberto T.; Miyamoto, Daniela A.; Going, Mayalu C. Retina Sector- Department of Ophthalmology Retina Sector- Department of Ophthalmology Ana Costa Hospital of Santos - HAC Ana Costa Hospital of Santos - HAC REFERENCES 1. Kraff MC, Sanders DR, Jampol LM, Lieberman HL. Factors affecting pseudophakic macular edema. Five randomized trials. Am Intraocular Implant Soc S J. 1999;11:380-5. 2. Wright PL, Wilkinson CP, Balyeat HD, Popham J, Reinke M. Angiographic cystoid macullar edema after posterior chamber lens implantation. Arch Ophthalmol. 1988;106(6):740- 4. 3. Irvine SR. Cystoid maculopathy. Surv Ophthalmol. 1976;21:1-17. 4. Martidis A, Duker JS, Puliafito CA. Intravitreal triamcinolone for refractory cystoid macular edema secondary to birdshot retinochoroidopathy. Arch Ophthalmol. 2001;119:1380-3. . n AGE EYE RACE SEX BCVA BEFORE BCVA AFTER DISEASE S LIO TREATMENT TREATMENT 1 `78 OD WHITE MALE 20/80 20/20 DM ACRYLI C 2 65 OE WHITE FEMALE 20/100 20/30 NONE SILICO N 3 69 AO WHITE FEMALE 20/60 - 20/60 20/25 - 20/20 DM ACRYLI C 4 72 OE WHITE MALE 20/80 20/20 NONE ACRYLI C 5 81 OE WHITE MALE 20/70 20/25 DM ACRYLI C 6 70 OD WHITE MALE 20/60 20/25 NONE SILICO N 7 69 OE WHITE FEMALE 20/70 20/30 NONE SILICO N 8 80 OD WHITE MALE 20/80 20/20 NONE SILICO N 9 50 OD WHITE MALE 20/60 20/20 NONE ACRYLI C

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. Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection. Gonçalves CA ..; Garcia, Marcos A..; Odloak CM. ; Campos, Paloma C.; Boro , Luiz Humberto T.; Miyamoto, Daniela A.; Going, Mayalu C. Retina Sector- Department of Ophthalmology - PowerPoint PPT Presentation

Transcript of Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection

Page 1: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection

Abstract

Purpose: To evaluate pseudophakic cystoid macular edema (CME) by optical coherence tomography (OCT) and determine the efficacy of intravitreal triamcinolone acetonide injections.

Methods: In this nonrandomized retrospective study, 10 eyes of 09 patients with persistent pseudophakic CME were treated with single triamcinolone acetonide injection and were followed up for 6 months . All patients underwent complete ophthalmologic examination including determination of best-corrected visual acuity, slit-lamp examination, tonometry, funduscopy and OCT recorded before and after 10, 20 days and 3 months the injection.

Results: Visual acuity and value increased in all patients after intravitreal triamcinolone acetonide injections. OCT showed improvement of the retinal thickness in the macular area. There was no increase of intraocular pressure .

Conclusion: Intravitreal triamcinolone acetonide injection is a promising therapeutic tool for chronic pseudophakic edema resistant to other medical treatment. However, further study is needed to assess the treatment’s long-term efficacy, its safety, and the need for retreatment. There is no significant difference in the use of acrylic lenses and silicon lens in our results.

Gonçalves CA..; Garcia, Marcos A..; Odloak CM. ;Campos, Paloma C.; Boro, Luiz Humberto T.; Miyamoto, Daniela A.; Going, Mayalu C.

Retina Sector- Department of OphthalmologyRetina Sector- Department of Ophthalmology Ana Costa Hospital of Santos - HACAna Costa Hospital of Santos - HAC

REFERENCES 1. Kraff MC, Sanders DR, Jampol LM, Lieberman HL. Factors affecting pseudophakic macular edema. Five randomized trials. Am Intraocular Implant Soc S J. 1999;11:380-5.2. Wright PL, Wilkinson CP, Balyeat HD, Popham J, Reinke M. Angiographic cystoid macullar edema after posterior chamber lens implantation. Arch Ophthalmol. 1988;106(6):740-4.3. Irvine SR. Cystoid maculopathy. Surv Ophthalmol. 1976;21:1-17. 4. Martidis A, Duker JS, Puliafito CA. Intravitreal triamcinolone for refractory cystoid macular edema secondary to birdshot retinochoroidopathy. Arch Ophthalmol. 2001;119:1380-3.

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n AGE EYE RACE SEX BCVA BEFORE BCVA AFTER DISEASES LIO

TREATMENT TREATMENT

1 `78 OD WHITE MALE 20/80 20/20 DM ACRYLIC

2 65 OE WHITE FEMALE 20/100 20/30 NONE SILICON

3 69 AO WHITE FEMALE 20/60 - 20/60 20/25 - 20/20 DM ACRYLIC

4 72 OE WHITE MALE 20/80 20/20 NONE ACRYLIC

5 81 OE WHITE MALE 20/70 20/25 DM ACRYLIC

6 70 OD WHITE MALE 20/60 20/25 NONE SILICON

7 69 OE WHITE FEMALE 20/70 20/30 NONE SILICON

8 80 OD WHITE MALE 20/80 20/20 NONE SILICON

9 50 OD WHITE MALE 20/60 20/20 NONE ACRYLIC

Page 2: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Gonçalves CA.; Garcia,MA.; Odloak CM. ; Campos, PC.; Boro, LHT.; Miyamoto, DA.; Going, MC.

Retina Sector- Department of OphthalmologyRetina Sector- Department of Ophthalmology Ana Costa Ana Costa Hospital of Santos – HACHospital of Santos – HAC

There is no financial interest by the author and There is no financial interest by the author and coauthor’s in this poster issue.coauthor’s in this poster issue.

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 3: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Purpose: To evaluate pseudophakic cystoid macular edema (CME) by optical coherence tomography (OCT) and determine the efficacy of intravitreal triamcinolone acetonide injections.

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 4: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Methods: In this nonrandomized retrospective study, 10 eyes of 09 patients with persistent pseudophakic CME were treated with single triamcinolone acetonide injection and were followed up for 6 months . All patients underwent complete ophthalmologic examination including determination of best-corrected visual acuity, slit-lamp examination, tonometry, funduscopy and OCT recorded before and after 10, 20 days and 3 months the injection.

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 5: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Results: Visual acuity and value increased in all patients after intravitreal triamcinolone acetonide injections. OCT showed improvement of the retinal thickness in the macular area. There was no increase of intraocular pressure. There is no significant difference in the use of acrylic lenses and silicon lens in our result

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 6: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Conclusion: Intravitreal triamcinolone acetonide injection is a promising therapeutic tool for chronic pseudophakic edema resistant to other medical treatment. However, further study is needed to assess the treatment’s long-term efficacy, its safety, and the need for retreatment.

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 7: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 8: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone

Acetonide Injection

Page 9: Treatment of  Pseudophakic  CME with a Single  Intravitreal Triamcinolone Acetonide  Injection

n AGE EYE RACE SEX BCVA BEFORE BCVA AFTER DISEASES LIO

TREATMENT TREATMENT

1 `78 OD WHITE MALE 20/80 20/20 DM ACRYLIC

2 65 OE WHITE FEMALE 20/100 20/30 NONE SILICON

3 69 AO WHITE FEMALE 20/60 - 20/60 20/25 - 20/20 DM ACRYLIC

4 72 OE WHITE MALE 20/80 20/20 NONE ACRYLIC

5 81 OE WHITE MALE 20/70 20/25 DM ACRYLIC

6 70 OD WHITE MALE 20/60 20/25 NONE SILICON

7 69 OE WHITE FEMALE 20/70 20/30 NONE SILICON

8 80 OD WHITE MALE 20/80 20/20 NONE SILICON

9 50 OD WHITE MALE 20/60 20/20 NONE ACRYLIC

Treatment of Pseudophakic CME with a Single Intravitreal Triamcinolone Acetonide Injection