Transgenic Animals - ftp. · PDF fileKnock out of pig genes -1.3 galactosyltransferase avoid...
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Transgenic Animals
Transcript of Transgenic Animals - ftp. · PDF fileKnock out of pig genes -1.3 galactosyltransferase avoid...
Transgenic Animals
Transgenic Animals
Transgenic Animals
Transgenic Animals
Transgenic Animals
“Cloning”
Transgenic Animals
Transgenic Animals
Tissue specific Expression
CFTR: Cystic Fibrosis Transmembrane Conductance Regulator
Transgenic Animals
Tissue specific Expression
Transgenic animals as organ supplier
Immunological Barriers
Hyperacute rejectionAcute vascular rejectionCellular rejectionChronic rejection
Porcine endogenous retroviruses
Humanizing the pig:
Introduction of Human Genes
Knock out of pig genes -1.3 galactosyltransferase avoid immunogenic reaction