TRANSCATHETER VALVE IN MAC - STS...•Low-profile aortic transcatheter valves (Sapien-3) (off-label...
Transcript of TRANSCATHETER VALVE IN MAC - STS...•Low-profile aortic transcatheter valves (Sapien-3) (off-label...
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TRANSCATHETER VALVE IN MACEnrico Ferrari, MD, PhD
Director minimally invasive valve surgery
Co-Director transcatheter heart valve program
Cariovascular Surgery Unit
Cardiocentro Ticino
Lugano, Switzerland
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Disclosure
• Consultant and proctor for Edwards Lifesciences
• Insitutional grant/research support from Edwards Lifesciences
• Insitutional grant/research support from Medtronic
STS/EACTS Latin America Cardiovascular Surgery Conference 20182
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• Low-profile aortic transcatheter valves (Sapien-3) (off-label use)
• Native mitral valve with severe Mitral Annular Calcifications (MAC)
• Old patients with high-risk profile and risk of annular rupture
• Accesses:
• percutaneous (femoral vein and trans-septal)
• Transapical (left mini-thoracotomy)
• direct transatrial (surgical mini-thoracotomy, with CPB, fibrillating heart)
Transcatheter valve in severe MAC
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Severe MAC
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Advantages of the surgical TAV in MAC
• Anterior leaflet ablation to prevent LVOT obstruction
• Direct annular measurement for valve sizing
• Direct visual implantation of the Sapien-3 valve (TA system)
• Valve fixation with surgical stitches to prevent valve displacement
• Use of “annular stabilisation technique” to prevent PVL
• Allows combined surgical procedures (TVR, CABG)
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Surgical TAV in MAC
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Results from the global registry
• Multicentric global registry (51 centers, 11 countries)
• Compassionate use of aortic transcatheter valves in MAC
• 116 patients (up to end 2017)
• Mean STS score: 15±11
• Data presented at EuroPCR by Dr Mayra Guerrero
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Results from the global registry
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Results from the global registry
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Results from the global registry
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Results from the global registry
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Results from the global registry
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Devices
SAPIEN-3Ferrari E, Dvir D, Guerrero M. Transatheter mitral valve replacement in degenerated calcified native mitral valves: is the currently available technology
suitable? Eur J Cardiothorac Surg. 2016;50:391-395
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PVL
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New «annulus stabilization technique» prevents PVLFerrari E, et al. Aortic annulus stabilization technique for rapid deployment aortic valve replacement. Innovations. 2015;10:360-362
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PVL prevention
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Ferrari E, et al. Aortic annulus stabilization technique for rapid deployment aortic valve replacement. Innovations. 2015;10:360-362
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LVOT
Surgical removal of the LAM prevents LVOT obstruction
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LVOT
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Surgical removal of the LAM prevents LVOT obstruction
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Conclusions
• Transcather valve in MAC in high-risk patients is still associated
with procedural complications and high mortality.
• Patients surviving 30-days have improved symptoms.
• The available technology was not developed for mitral valves.
• Surgical TAV in MAC guarantees AML removal, sizing, visual
implantation (repositioning if required), valve fixation, no PVL.
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THANK YOU