TRAMATIC BRAIN INJURY 1 - University Of Maryland · TRAMATIC BRAIN INJURY 1 ... Nose and Throat...

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Session 1 Saturday, May 1 TRAMATIC BRAIN INJURY 1 9:00‐10:20 am Room: Kim Lecture Hall Room 1110 Session Co‐Chairs: Thomas McGrath Indian Head Division, NSWC – Naval Surface Warfare Center Balakumar Balachandran Dept. of Mechanical Engineering, University of Maryland 9:00‐9:20 am Traumatic Brain Injury in Rats Caused by Blast‐Induced Hyper‐acceleration G. Fiskum 1 , J. Hazelton 1 , R. Gullapalli 2 , and W.L. Fourney 3 1 University of Maryland School of Medicine, Dept. of Anesthesiology and the Shock, Trauma, and Anesthesiology Research Center (STAR) 2 University of Maryland School of Medicine Dept. of Diagnostic Radiology 3 University of Maryland School of Engineering, Dept. of Mechanical Engineering and the Center of Energetics Concepts Development 9:20‐9:40 am Early Metabolic and Structural Changes in the Rat Brain following Trauma In Vivo using MRI S. Xu 1,3 , J. Zhuo 1,3 , J. Racz 2 , S. Roys 1,3 , D. Shi 1,3 , G. Fiskum 2,3 , R. Gullapalli 1,3 1 Department of Diagnostic Radiology and Nuclear Medicine 2 Department of Anesthesiology and the Center for Shock Trauma and Anesthesiology Research (STAR) 3 Core for Translational Research in Imaging, Maryland University of Maryland School of Medicine, Baltimore, MD 21201, USA 9:40‐10:00 am Principal Components of Brain Deformation in Response to Skull Acceleration: The Roles of Sliding and Tethering Between the Brain and Skull Teresa M. Abney 1 , Y. Aaron Feng 1 , Robert Pless 2 , Ruth J. Okamoto 1 , Guy M. Genin 1 , and Philip V. Bayly 1,3 1 Dept of Mechanical, Aerospace and Structural Engineering, 2 Dept of Computer Science and Engineering, and 3 Dept of Biomedical Engineering, Washington University in St. Louis, Saint Louis, USA 10:00‐10:20 am Investigations into Wave Propagation in Soft Tissue M. F. Valdez and B. Balachandran Department of Mechanical Engineering, University of Maryland, College Park, MD 20742 *student paper underline denotes presenting author

Transcript of TRAMATIC BRAIN INJURY 1 - University Of Maryland · TRAMATIC BRAIN INJURY 1 ... Nose and Throat...

Session1 Saturday,May1 TRAMATICBRAININJURY1

9:00‐10:20am Room: KimLectureHallRoom1110

SessionCo‐Chairs: ThomasMcGrathIndianHeadDivision,NSWC–NavalSurfaceWarfareCenterBalakumarBalachandranDept.ofMechanicalEngineering,UniversityofMaryland

9:00‐9:20am TraumaticBrainInjuryinRatsCausedbyBlast‐InducedHyper‐accelerationG.Fiskum1,J.Hazelton1,R.Gullapalli2,andW.L.Fourney31UniversityofMarylandSchoolofMedicine,Dept.ofAnesthesiologyandtheShock,Trauma,andAnesthesiologyResearchCenter(STAR)2UniversityofMarylandSchoolofMedicineDept.ofDiagnosticRadiology3UniversityofMarylandSchoolofEngineering,Dept.ofMechanicalEngineeringandtheCenterofEnergeticsConceptsDevelopment

9:20‐9:40am EarlyMetabolicandStructuralChangesintheRatBrainfollowingTraumaInVivousingMRIS.Xu1,3,J.Zhuo1,3,J.Racz2,S.Roys1,3,D.Shi1,3,G.Fiskum2,3,R.Gullapalli1,31DepartmentofDiagnosticRadiologyandNuclearMedicine2DepartmentofAnesthesiologyandtheCenterforShockTraumaandAnesthesiologyResearch(STAR)3CoreforTranslationalResearchinImaging,MarylandUniversityofMarylandSchoolofMedicine,Baltimore,MD21201,USA

9:40‐10:00am PrincipalComponentsofBrainDeformationinResponsetoSkull Acceleration:TheRolesofSlidingandTetheringBetweentheBrainand Skull

TeresaM.Abney1,Y.AaronFeng1,RobertPless2,RuthJ.Okamoto1,GuyM.Genin1,andPhilipV.Bayly1,31Dept of Mechanical, Aerospace and Structural Engineering, 2Dept of Computer Science andEngineering, and 3Dept of Biomedical Engineering, Washington University in St. Louis, SaintLouis,USA

10:00‐10:20am InvestigationsintoWavePropagationinSoftTissue M.F.ValdezandB.Balachandran DepartmentofMechanicalEngineering,UniversityofMaryland,CollegePark,MD20742*studentpaper underlinedenotespresentingauthor

Session2 Saturday,May1 AuditoryScience

9:00‐10:20am Room: KayBoardKimRoom1111

SessionCo‐Chairs: DidierADepireux InstituteforSystemsResearch,UniversityofMaryland,CollegePark,MD

MonitaChatterjee Dept.ofHearingandSpeechSciences,UniversityofMaryland,CollegePark,MD

9:00‐9:20am HairCellRegenerationintheMammalianEar,isGeneTherapytheAnswer?

MatthewKelleySectiononDevelopmentalNeuroscience,NationalInstituteonDeafnessandotherCommunicationDisorders,NationalInstitutesofHealth,Bethesda,Maryland

9:20‐9:40am MagnetoencephalographyandAuditoryNeuralRepresentationsJ.Z.Simon1,2andN.Ding11Dept of Electrical & Computer Engineering, University of Maryland, College ParkMD 20815,USA2DeptofBiology,UniversityofMaryland,CollegeParkMD20815,USA

9:40‐10:00am VoicePitchProcessingwithCochlearImplantsMonitaChatterjee1,Shu‐ChenPeng2,LaurenWawroski3andCherishOberzut11CochlearImplantsandPsychophysicsLab,Dept.ofHearingandSpeechSciences,UniversityofMaryland,CollegePark,MD,USA2DivisionofOpthalmicandEar,NoseandThroatDevices,OfficeofDeviceEvaluation,CenterforDevicesandRadiologicHealth,USFoodandDraftAdministration,SilverSpring,MD,USA3Children’sNationalMedicalCenter,Washington,DC,USA

10:00‐10:20am TranscranialMagneticStimulationasaToolforInvestigatingandTreating Tinnitus

G.FWittenberg1,21VeteransAffairsMarylandHealthCareSystem/GeriatricsResearch,EducationandClinicalCare,Baltimore,Maryland,USA2Dept.ofNeurology,UniversityofMaryland,Baltimore,Maryland,USA

*studentpaper underlinedenotespresentingauthor

Session3 Saturday,May1 BIOENGINEERINGEDUCATION

9:00‐10:20am Room: KayBoardKimRoom1107

SessionCo‐Chairs: ArthurT.Johnson FischellDepartmentofBioengineering,Univ.ofMaryland

EileenHaaseDept.ofBiomedicalEngineering,JohnsHopkinsUniv.

9:00‐9:20am ACourseGuidelineforBiomedicalEngineeringModelingandDesignfor Freshmen

W.C.Wong1andE.B.Haase11DepartmentofBiomedicalEngineering,JohnsHopkinsUniversity,Baltimore,MD

9:20‐9:40am TheBasicsofBioengineeringEducationArthurT.JohnsonFischellDepartmentofBioengineering,CollegePark,MD20742

*9:40‐10:00am

HealthiManage:AnIndividualizedPredictionAlgorithmforType2DiabetesChronicDiseaseControlSalim Chemlal1, Sheri Colberg1, Marta Satin‐Smith2, Eric Gyuricsko2, Tom Hubbard2, Mark W.Scerbo1,FredericD.McKenzie11OldDominionUniversity,Norfolk,VA,USA2EasternVirginiaMedicalSchool,Norfolk,VA,USA

*studentpaper underlinedenotespresentingauthor

Session4 Saturday,May1 CELLULARENGINEERING1

9:00‐10:20am Room: PepcoSeminarKimRoom1105

SessionCo‐Chairs: DulcianaChanU.S.FoodandDrugAdministration

DeepaSritharanU.S.NationalInstituteofStandardsandTechnology

*9:00‐9:20am MyosinIIisanActiveStressSensorattheCoreofaCellDivisionControlSystemYeeSeirKee,RichardFirtel,PabloIglesias,DouglasRobinsonDepartmentofChemicalandBiomolecularEngineering,JohnsHopkinsUniversity

9:20‐9:40am Cooperative InteractionsbetweenMyosinIIandCortexillinIMediatedbyActinFilamentsduringCellularDeformationTianzhiLuo1andDouglasN.Robinson1,2,31SchoolofMedicine/DepartmentofCellBiology,JohnsHopkinsUniversity,Baltimore,USA2School of Medicine/Department of Pharmacology and Molecular Sciences, Johns HopkinsUniversity,Baltimore,USA3School of Engineering/Department of Chemical and Biomolecular Engineering, JohnsHopkinsUniversity,Baltimore,USA

*9:40‐10:00am ConductionPropertiesofCulturedNeonatalRatVentricularCardiac MyocytesinResponsetoUniaxialMechanicalStress

DulcianaChan,FelipeAguelUSFoodandDrugAdministration,WhiteOak,MD

*10:00‐10:20am AHigh‐Throughput,Non‐invasiveSensortoMeasureCellularOxygen ConsumptionRates DeepaSritharan,PeterThomas,JaneRomantseva,ZachEwart,SamuelForry USNationalInstituteofStandardsandTechnology

*studentpaper underlinedenotespresentingauthor

Session5 Saturday,May1 NANOTECHNOLOGY1

9:00‐10:20am Room: KimBuildingRoom2111

SessionCo‐Chairs: HomerNazeranBioMedEngConsulting,ElPaso,Texas,USA

A.J.McGoronBiomedicalEngineeringDept.,FloridaInternationalUniversity,Miami,FL

*9:00‐9:20am MeasuringInVivoEffectsofChemotherapyTreatmentonCardiac Permeability

A.Fernandez‐Fernandez1,D.A.Carvajal1andA.J.McGoron11BiomedicalEngineeringDept.,FloridaInternationalUniversity,Miami,FL

*9:20‐9:40am Nanoscale“DNAbaskets”fortheDeliveryofsiRNAA.C. Zirzow1, M. Skoblov2, A. Patanarut3, C. Smith4, A. Fisher4, V. Chandhoke1, and A.Baranova1,2,1Department of Molecular an Microbiology, College of Science, George Mason University,Fairfax,USA, 2ResearchCenter forMedicalGenetics, RAMS,Moskvorechie Str., 1,Moscow,RussianFederation,3DepartmentofChemistryandBiochemistry,CollegeofScience,GeorgeMasonUniversity,Fairfax,USA4U.S.ArmyEngineerResearchandDevelopmentCenter‐GeospatialResearchandEngineeringDivision,Alexandria,USA

9:40‐10:00am NanoscaleGlutathionePatchesImproveOrganFunctionHomerNazeran1andSherryBlake‐Greenberg21BioMedEngConsulting,ElPaso,Texas,USA2HealthIntegrationTherapy,PalosVerdesEstates,California,USA

10:00‐10:20am NanoscaleCarnosinePatchesImproveOrganFunctionHomerNazeran1andSherryBlake‐Greenberg21BioMedEngConsulting,ElPaso,Texas,USA2HealthIntegrationTherapy,PalosVerdesEstates,California,USA

*studentpaper underlinedenotespresentingauthor

Session6 Saturday,May2 TissueEngineering1

9:00‐10:20am Room: AnimalSci.Bldg.Room0408

SessionCo‐Chairs: WarrenGraysonDept.ofBiomedicalEngineering,JohnsHopkinsUniversity

KyobumKimFischellDept.ofBioengineering,Univ.ofMaryland

*9:00‐9:20am EngineeringVascularizedHumanBoneGraftsW.L.Grayson1,2,M.Park1,D.Kaplan3andG.Vunjak‐Novakovic11ColumbiaUniversity/BiomedicalEngineering,NewYork,USA2JohnsHopkinsUniversity/BiomedicalEngineering,Baltimore,USA3TuftsUniversity/BiomedicalEngineering,Medford,USA

9:20‐9:40am FunctionalSurfacestoControlVascularDifferentiationandAssemblyLaura Dickinson1, Matthew Moura1, Chia Chi Ho1, Geoffrey Wang1, Kathleen Stebe2, SharonGerecht11JohnsHopkinsUniversity/Chemical&BiomolecularEngineering,Baltimore,USA2UniversityofPennsylvania/Chemical&BiomolecularEngineering,Philadelphia,USA

9:40‐10:00am CellSheetEngineeringofSmall‐diameterBloodVesselfromAligned HumanMesenchymalStemCells FengZhao,KamW.Leong DukeUniversity,BiomedicalEngineering,Durham,USA

10:00–10:20amGumArabic‐chitosanCompositeBiopolymerScaffoldsforBoneTissue Engineering

R.A.Silva1,P.Mehl2,O.C.Wilson11Biomedical Engineering Department, BONE/CRAB Lab, The Catholic University of America,Washington,DC,USA.2Vitreous State Laboratory, Physics Department, The Catholic University of America,Washington,DC,USA.

*studentpaper underlinedenotespresentingauthor

Session7 Saturday,May1 DEVICES1

9:00‐10:20am Room: AnimalSci.Bldg.Room0412

SessionCo‐Chairs: SrilekhaSarkarDasOfficeoftheScienceandEngineeringLaboratories,FDA,USA

TamásHaidegger BudapestUniversityofTechnologyandEconomics,Hungary

*9:00‐9:20am Non‐invasiveEstimationofIntracranialPressurebyMeansofRetinal VenousPulsatility

S.MojtabaGolzan,StuartLGrahamandAlbertoAvolioAustralianSchoolofAdvancedMedicine,MacquarieUniversity,Sydney,Australia

9:20‐9:40am ApparatusforQuantitativeSlit‐LampOcularFluorometryJoséP.Domingues1,2,IsaBranco2andAntónioM.Morgado1,21IBILI–BiomedicalInstituteforResearchonLightandImaging,CoimbraPortugal2PhysicsDepartment,UniversityofCoimbra,Portugal

9:40‐10:00am ChangesinViscoelasticPropertiesofLatexCondomsDuetoPersonal Lubricants

Srilekha Sarkar Das1, Matthew Schwerin1, Donna Walsh1, Charles Tack2, D. ColemanRichardson11Office of the Science and Engineering Laboratories, Center for Devices and RadiologicalHealth,FoodandDrugAdministration,2BiomedicalEngineering,MarquetteUniversity

*10:00‐10:20am TowardstheObjectiveEvaluationofHandDisinfection

ÁkosLehotsky,MelindaNagyandTamásHaideggerBudapestUniversityofTechnologyandEconomics,Dept.ofControlEngineeringandInformationTechnology,Budapest,Hungary

*studentpaper underlinedenotespresentingauthor

Session8 Saturday,May1 NEURALSYSTEMSENGINEERING

10:40am‐12:00 Room: KimLectureHallRoom1110

SessionChair: N.Peixoto ElectricalandComputerEngineeringDept.,GeorgeMasonUniversity

*10:40‐11:00am InVitroModelsforMeasuringChargeStorageCapacityK.F.Zaidi3,Z.H.Benchekroun1,S.Minnikanti1,J.Pancrazio1,andN.Peixoto1,21ElectricalandComputerEngineeringDept.and2KrasnowInstituteforAdvancedStudy,GeorgeMasonUniversity,FairfaxVA,USA3A.JamesClarkSchoolofEngineering,UniversityofMaryland,CollegePark,MD

*11:00‐11:20am DiscoveryofLong‐latencySomatosensoryEvokedPotentialsasa MarkerofCardiacArrestInducedBrainInjury

DanWu,JaiMadhok,Young‐SeokChoi,XiaofengJia,NitishV.ThakorDepartmentofBiomedicalEngineering,JohnsHopkinsUniversity,Baltimore,MD21029

*11:20‐11:40am BrainElectricalStimulationEthicalandSafetyIssuesMulugetaSemeworkStateUniversityofNewYork,DownstateMedicalCenter,Brooklyn,USA

*11:40am‐12:00 InVivoCharacterizationofEpilepticTissuewithTime‐Dependent,DiffuseReflectanceSpectroscopyNitin Yadav1, Sanghoon Oh1,2, Sanjeev Bhatia2, John Ragheb2, Prasanna Jayakar2, MichaelDuchowny2,Wei‐ChiangLin1,21DepartmentofBiomedicalEngineering,FloridaInternationalUniversity,Miami,FL,USA2TheBrainInstitute,MiamiChildren’sHospital,Miami,FL,USA

*studentpaper underlinedenotespresentingauthor

Session9 Saturday,May1 SpecialTopics1

10:40am‐12:00 Room: KayBoardKimRoom1111

SessionCo‐Chairs: DidierADepireux InstituteforSystemsResearch,UofMaryland,CollegePark,MD21042

MonitaChatterjee Dept.ofHearingandSpeechSciences,UniversityofMaryland,CollegePark,MD

*10:40‐11:00am

ModelingfortheImpactofAnesthesiaonNeuralActivityintheAuditorySystemZ.B.Tan1,L.Y.Wang1,H.Wang2,X.G.Zhang3,andJ.S.Zhang3,41Dept.ofElectricalandComputerEngineering,WayneStateUniversity,Detroit,Michigan48202,USA2Dept.ofAnesthesiology,WayneStateUniversity,Detroit,Michigan48202,USA3Dept.ofOtolaryngology,SchoolofMedicine,WayneStateUniversity,Detroit,Michigan48201,USA4Dept.ofCommunicationSci.andDis,CollegeofLiberalArtsandSciences,WayneStateUniversity,Detroit,Michigan48202,USA

*11:00‐11:20am

CorticalExcitabilityChangesafterRepetitiveSelf‐Regulatedvs.TrackingMovementsoftheHandS.B.Godfrey1,P.S.Lum1,2,C.N.Schabowsky1,andM.L.Harris‐Love21TheCatholicUniversityofAmerica,Washington,D.C.,USA2NationalRehabilitationHospital,Washington,D.C.,USA

11:20‐11:40am

WhattheENTwantsintheOR:BioengineeringProspectsD.A.Depireux,Ph.D.1andD.J.Eisenman,M.D.21InstituteforSystemsResearch,UofMaryland,CollegePark,MD210422DepartmentofOtorhinolaryngology‐Head&NeckSurgery,UofMaryland,Baltimore,MD21201

*11:40am‐12:00

AnInVitroBiomechanicalComparisonofHumanDermistoaSiliconeBiosimulantMaterialI.D.Wing1,2,H.A.Conner1,P.J.Biermann1andS.M.Belkoff2,31JohnsHopkinsUniversity/AppliedPhysicsLaboratory,Laurel,MD,USA2JohnsHopkinsUniversity/Dept.ofMechanicalEngineering,Baltimore,MD,USA3JohnsHopkinsMedicalInstitutions/Dept.ofOrthopaedicSurgery,Baltimore,MD,USA

*studentpaper underlinedenotespresentingauthor

Session10 Saturday,May1 IMAGING1

10:40am‐12:00 Room: KayBoardKimRoom1107

SessionCo‐Chairs: YuChen

FischellDept.ofBioengineering,Univ.ofMaryland RajShekhar

Dept.ofDiagnosticRadiation,UniversityofMarylandatBaltimore

10:40‐11:00am TargetedDeliveryofMolecularProbesforInVivoElectronParamagneticResonanceImagingS.R.Burks1,2,E.D.Barth3,S.S.Martin2,4,G.M.Rosen1,5,H.J.Halpern3,andJ.P.Y.Kao1,21Center for Biomedical Engineering and Technology, University of Maryland, and MedicalBiotechnology Center, University of Maryland Biotechnology Institute, and Center for EPRImagingInVivoPhysiology,UniversityofMaryland,Baltimore,USA2DepartmentofPhysiology,UniversityofMaryland,Baltimore,USA3DepartmentofRadiationOncologyandCenterforEPRImagingInVivoPhysiology,UniversityofChicago,Chicago,USA4MarleneandStewartGreenebaumCancerCenter,UniversityofMaryland,Baltimore,USA5DepartmentofPharmaceuticalSciences,UniversityofMaryland,Baltimore,USA

11:00‐11:20am NewToolsforImage‐basedMeshGenerationof3DImagingDataP.G.Young1,D.Raymont1,V.BuiXuan2,R.T.Cotton21SchoolofEngineering,MathematicsandPhysicalSciences,UniversityofExeter,Exeter,UK2SoftwareDevelopment&TechnicalServices,Simpleware,Exeter,UK

11:20‐11:40am CharacterizationofSpeedandAccuracyofaNonrigidRegistration AcceleratoronPre‐andIntraproceduralImages

Raj Shekhar1, William Plishker1, Sheng Xu2, Jochen Kruecker2, Peng Lei1, AradhanaVenkatesan3,BradfordWood31Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland,Baltimore,Maryland,USA2PhilipsResearchNorthAmerica,BriarcliffManor,NewYork,USA3Center for Interventional Oncology, Clinical Center andNational Cancer Institute, NationalInstitutesofHealth,Bethesda,Maryland,USA

*11:40‐12:00am AssessmentofKidneyStructureandFunctionusingGRINLensBased LaparoscopewithOpticalCoherenceTomography

C.W.Chen1,J.Wierwille2,M.L.Onozato3,P.M.Andrews3,M.Phelan4,J.Borin4andY.Chen1,21DepartmentofElectricalandComputerEngineering2FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD20742USA3GeorgetownUniversitySchoolofMedicine,Washington,DC20007USA4Department of Surgery, University ofMaryland School ofMedicine, Baltimore, MD 21201USA

*studentpaper underlinedenotespresentingauthor

Session11 Saturday,May1 KINEMATICS

10:40am‐12:00 Room: PepcoSeminarKimRoom1105

SessionCo‐Chairs: ElizabethBrokawNationalRehabilitationHospital,Washington,D.C.

JamesBorrelliDeptofMechanicalEngineering,Univ.ofMaryland

*10:40‐11:00am TimeIndependentFunctionalTrainingofInter‐jointArmCoordinationUsingtheARMinIIIRobotE.B.Brokaw1,2,T.Nef1,2,T.M.Murray1,2,andP.S.Lum1,21Center for Applied Biomechanics and Rehabilitation Research, National RehabilitationHospital,Washington,D.C.,U.S.A.2BiomedicalEngineering,TheCatholicUniversityofAmerica,WashingtonD.C.,U.S.A.

*11:00‐11:20am KinematicAnalysisinRobotAssistedFemurFractureReduction:Fuzzy LogicApproach

WangSong1,ChenYonghua1,YERuihua1andYauWaiPan21DepartmentofMechanicalEngineering,TheUniversityofHongKong,HongKong,China2Department ofOrthopaedics and Traumatology, TheUniversity ofHong Kong,HongKong,China

*11:20‐11:40am CompensationforWeakHipAbductorsinGaitAssistedbyaNovelCrutch‐LikeDeviceJ.R.BorrelliandH.W.HaslachJr.UniversityofMaryland/DepartmentofMechanicalEngineering,CollegePark,USA

11:40‐12:00am ANewElectromechanicalDeviceforMinimizationoftheKneeShearJointLoadinLegExtensionEquipmentGiordanoFranceschini,FrancescoMastrandrea,VanessaCarnevali,AndreaBiscarini,PaoloBenvenutiIndustrialEngineeringDepartmentUniversityofPerugia,Italy

*studentpaper underlinedenotespresentingauthor

Session12 Saturday,May1 NANOTECHNOLOGY2

10:40am‐12:00 Room: KimBuildingRoom2111

SessionChair: KimihiroSusumuU.S.NavalResearchLaboratory

10:40‐11:00am MultipleLumiphore‐BoundNanoparticlesforInVivoQuantificationofLocalizedOxygenLevelsJ.L.VanDruff,W.Zhou,E.Asman,andJ.B.LeachUniversity of Maryland, Baltimore County, Department of Chemical and BiochemicalEngineering,1000HilltopCircle,Baltimore,MD,USA

11:00‐11:20am ModularCompactLigandsforBiocompatibleSemiconductorQuantumDotsandGoldNanoparticleswithExtendedpHandIonicStability

KimihiroSusumu,EunkeuOh,MichaelHStewart,KellyBoeneman,DuaneEPrasuhn,JamesBDelehanty,IgorLMedintz,AlanLHustonU.S.NavalResearchLaboratory

11:20‐11:40am Ion‐MobilityCharacterizationofFunctionalizedandAggregatedGold nanoparticlesforDrugDelivery

D‐H.Tsai1,2,L.F.PeaseIII2,3.R.A.Zangmeister2,S.Guha1,2,M.J.Tarlov2,andM.R.Zachariah1,21UniversityofMaryland,CollegePark,Maryland,U.S.2NationalInstituteofStandardsandTechnology,Gaithersburg,Maryland,U.S.3UniversityofUtah,SaltLakeCity,Utah,U.S.

*11:40am‐12:00 CellSpecificTargetingofLipid‐basedNanoparticlesforEnhanced DeliveryofTherapeuticAgents

BrandonSmith,KristinLoomis,AmichaiYavlovich,AlexHaber,DanielleNeedle,IlyaLyakhov,JacekCapala,YangFeng,XiaodongXiao,DimiterDimitrov,RobertBlumenthal,AnuPuriNCI‐Frederick,NIH

*studentpaper underlinedenotespresentingauthor

Session13 Saturday,May1 BIOMATERIALS2

10:40am‐12:00 Room: AnimalSci.Bldg.Room0408

SessionCo‐Chairs: OttoC.Wilson,Jr.CatholicUniversityofAmerica,Washington,DC

10:40‐11:00am MechanismandDirectVisualizationofElectrodepositionofthe PolysaccharideChitosan

YiCheng1,XiaolongLuo2,JordanBetz1,3,OmarBekdash1,3,andGaryW.Rubloff1,41InstituteforSystemsResearch(ISR),UniversityofMaryland,CollegePark,MD2CenterforBiosystemsResearch,Univ.ofMarylandBiotechnologyInstitute,CollegePark,3FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD4DepartmentofMaterialsScienceandEngineering,UniversityofMaryland,CollegePark,MD

*11:00‐11:20am Chito‐Cotton:ChitosanCoatedCotton‐BasedScaffoldO.Agubuzo1,P.Mehl2,O.C.Wilson1andR.Silva11DepartmentofBiomedicalEngineering,CatholicUniversityofAmerica,Washington,DC2DepartmentofPhysics,CatholicUniversityofAmerica,Washington,DC

*11:20‐11:40am EffectsofTemperatureonthePerformanceofFootwearFoams: ReviewofDevelopments

M.R.Shariatmadari,R.EnglishandG.RothwellLiverpoolJohnMooresUniversity,SchoolofEngineering,Liverpool,UK

11:40am‐12:00 ATissueEquivalentPhantomoftheHumanTorsoforInVivo BiocompatibleCommunications

David M. Peterson1, 2, Walker Turner1, Kevin Pham1, Hong Yu1, Rizwan Bashirullah1, NeilEuliano2andJefferyR.Fitzsimmons11UniversityofFlorida,Gainesville,FL,USA2ConvergentEngineering,GainesvilleFL,USA

*studentpaper underlinedenotespresentingauthor

Session14 Saturday,May1 IMPLANTS

10:40am‐12:00 Room: AnimalSci.Bldg.Room0412

SessionCo‐Chairs: SubrataSahaSUNYDownstateMedicalCenter,Brooklyn,NewYork

GerielEttienne‐Modeste UniversityofMaryland–BaltimoreCounty

10:40‐11:00am Nano‐Wear‐ParticulatesElicitaSizeandDoseDependentResponseby RAW264.7MurineMonocyte/MacrophageCells

MrinalK.Musib,SubrataSahaDepartment of Orthopedic Surgery and RehabilitationMedicine, SUNY Downstate MedicalCenter,Brooklyn,NewYork11203

*11:00‐11:20am Viscous Behavior of Different Concentrations of Bovine Calf SerumBeforeandafterWearTesting

GerielEttienne‐Modeste UniversityofMaryland–BaltimoreCounty

*11:20‐11:40am Progressive Wear Damage Analysis on Retrieved UHMWPE TibialImplants

N.Camacho,S.W.Stafford,andL.TruebaJr. Univ.ofTexasatElPaso/MetallurgicalandMaterialsEngineeringDepartment,ElPaso,TX

*studentpaper underlinedenotespresentingauthor

Session16 Saturday,May1 TRAMATICBRAININJURY2

1:30‐3:30pm Room: KimLectureHallRoom1110

SessionCo‐Chairs: ThomasMcGrathIndianHeadDivision,NSWC–NavalSurfaceWarfareCenterAndrewMerkleJohnsHopkinsUniversityAPL

1:30‐1:50pm CorrelatingTissueResponsewithAnatomicalLocationofmTBIusingaHumanHeadFiniteElementModelunderSimulatedBlastConditionsT.P.Harrigan1,J.C.Roberts1,2,E.E.Ward1,andA.C.Merkle11TheJohnsHopkinsUniversityAppliedPhysicsLaboratory,Laurel,Maryland,USA2TheJohnsHopkinsUniversityDepartmentofMechanicalEngineering,Baltimore,MD,USA

1:50‐2:10pm HumanSurrogateHeadResponsetoDynamicOverpressureLoadingin ProtectedandUnprotectedConditions

A.C.Merkle1,I.D.Wing1andJ.C.Roberts1,21TheJohnsHopkinsUniversityAppliedPhysicsLaboratory,Laurel,Maryland,USA2TheJohnsHopkinsUniversityDepartmentofMechanicalEngineering,Baltimore,MD,USA

*2:10‐2:30pm Blast‐inducedTraumaticBrainInjury:UsingaShockTubetoRecreateaBattlefieldInjuryintheLaboratoryJ.B. Long1, L. Tong1, R.A. Bauman1, J.L. Atkins1, A.J. Januszkiewicz1, C. Riccio1, R. Gharavi1, R.Shoge1,S.Parks2,D.V.Ritzel3,andT.B.Bentley11Division of Brain Dysfunction and Blast Injury, Walter Reed Army Institute of Research,2OperationsResearchandApplications,Fredericksburg,VA22408,USA3Dyn‐FXConsultingLtd.,Amherstburg,Ontario,N9V2T5Canada

2:30‐2:50pm WavePropagationintheHumanBrainandSkullImagedInVivobyMRElastographyE.H.Clayton1,G.M.Genin1andP.V.Bayly1,21Washington University in St. Louis/Department of Mechanical, Aerospace and StructuralEngineering,SaintLouis,USA2WashingtonUniversityinSt.Louis/DepartmentofBiomedicalEngineering,SaintLouis,USA

2:50‐3:10pm CavitationasaPossibleTraumaticBrainInjury(TBI)DamageMechanismAndrewWardlawandJackGoellerAdvancedTechnologyandResearchCorporation,Columbia,MD.,21046,USA

*studentpaper underlinedenotespresentingauthor

Session17 Saturday,May1 TISSUEENGINEERING2

1:30‐3:30 Room: KayBoardKimRoom1111

SessionCo‐Chairs: OttoWilson,Jr. CatholicUniversityofAmerica

SidneySit BiomedicalEngineeringProgram,LouisianaTechUniversity,Ruston,Louisiana

*1:30‐1:50 ModificationofHydrogelScaffoldsfortheModulationofCorneal EpithelialCellResponses

L.G.Reis,P.PattekariandP.S.Sit BiomedicalEngineeringProgram,LouisianaTechUniversity,Ruston,Louisiana71272,USA

*1:50‐2:10 MakingofFunctionalTissueEngineeredHeartValveS.S.PatelandY.S.Morsi

BiomechanicsandTissueEngineeringGroup,FacultyofEngineeringandIndustrialSciences,SwinburneUniversityofTechnology,Hawthorn,Australia

2:10‐2:30 QuantificationofAdenineusingChitosan‐mediatedSERSSubstrates XiaolongLuo,GaryRubloff,WilliamBentley FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD

*2:30‐2:50 TiesthatBind:EvaluationofCollagenIandα‐chitinTiffanyOmokanwayeandOttoWilson,Jr.CatholicUniversityofAmerica/BiomedicalEngineeringDepartment,Washington,D.C.,USA

*2:50‐3:10 Chitosan/Poly(ε‐caprolactone)CompositeHydrogelforTissue EngineeringApplications

XiaZhong1,ChengdongJi1,SergeiG.Kazarian2,AndrewRuys3,FaribaDehghani11SchoolofChemicalandBiomolecularEngineering,TheUniversityofSydney,Sydney,Australia2SchoolofChemicalEngineering,ImperialCollegeLondon,London,UK3SchoolofAerospace,Mechanical&MechatronicEngineering,TheUniversityofSydney,Sydney,Australia

*studentpaper underlinedenotespresentingauthor

Session18 Saturday,May1 DISEASEMODELING

1:30‐3:30pm Room: KayBoardKimRoom1107

SessionCo‐Chairs: BinhQ.TranTheCatholicUniversityofAmerica,Washington,DC

DoronLevy Dept.ofMathematics,UniversityofMaryland

*1:30‐1:50pm MathematicalModelingofEbolaVirusDynamicsasaSteptowards RationalVaccineDesign

SophiaBanton,ZviRothandMirjanaPavlovicFloridaAtlanticUniversity/ElectricalEngineering(Bioengineering),BocaRaton,USA

1:50‐2:10pm RespiratoryImpedanceValuesinAdultsareRelativelyInsensitivetoMeadModelLungComplianceandChestWallComplianceParametersBillDiong1,MichaelD.Goldman2andHomerNazeran21Engineering,TexasChristianUniversity,FortWorth,TX,TX,U.S.A.2ElectricalandComputerEngineering,UniversityofTexasatElPaso,ElPaso,TX,U.S.A.

*2:10‐2:30pm ASystemsBiologyModelofAlzheimer’sDiseaseincorporatingSpatial‐TemporalDistributionofBetaAmyloidCRKyrtsos1,2andJSBaras1,2,31FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD,US2InstituteforSystemsResearch,UniversityofMaryland,CollegePark,MD,US3DepartmentofElectricalEngineering,UniversityofMaryland,CollegePark,MD,US

*2:30‐2:50pm AMathematicalModelofthePrimaryTCellResponsewithContractionGovernedbyAdaptiveRegulatoryTCellsS.N.Wilson1,P.Lee2andD.Levy11Mathematics Department and Center for Scientific Computing and Mathematical Modeling(CSCAMM),UniversityofMaryland,CollegePark,MD,USA2DivisionofHematology,DepartmentofMedicine,StanfordUniversity,Stanford,CA,USA

*2:50‐3:10pm AMathematicalModelforMicroenvironmentalControlofTumorGrowthA.R.Galante,D.LevyandC.TomasettiDepartmentofMathematicsandCenterforScientificComputationandMathematicalModeling(CSCAMM),UniversityofMaryland,CollegePark,MD,USA

3:10‐3:30pm AssessingtheUsabilityofWeb‐basedPersonalHealthRecords PedroGonzales1,BinhQ.Tran2

1Department of Electrical Engineering & Computer Science, 2Department of BiomedicalEngineeringTheCatholicUniversityofAmerica,WashingtonDC,USA

*studentpaper underlinedenotespresentingauthor

Session19 Saturday,May1 DRUGDELIVERY

1:30‐3:30pm Room: PepcoSeminarKimRoom1105

SessionCo‐Chairs: AnthonyJ.McGoron FloridaInternationalUniversity,Miami,FL

SilviaMuroFischellDept.ofBioengineering,Univ.ofMaryland

*1:30‐1:50pmTargetedDeliveryofDoxorubicinbyPLGANanoparticlesIncreasesDrug UptakeinCancerCellLines

TingjunLei,SupriyaSrinivasan,YuanTang,RomilaManchanda,AliciaFernandez‐Fernandez,AnthonyJ.McgoronBiomedicalEngineeringDepartment,FloridaInternationalUniversity,Miami,FL,UnitedStates

1:50‐2:10pm CellularUptakeandCytotoxicityofaNovelICG‐DOX‐PLGADualAgent PolymerNanoparticleDeliverySystem

RomilaManchanda,TingjunLei,YuanTang,AliciaFernandez‐Fernandez,AnthonyJ.McGoronDepartmentofBiomedicalEngineering,FloridaInternationalUniversity,10555WestFlaglerStreet,MiamiFL33174USA

*2:10‐2:30pm Electrospray–DifferentialMobilityAnalysis(ES‐DMA)for CharacterizationofHeatInducedAntibodyAggregates

SuvajyotiGuha1,2,JoshuaWayment2,MichaelJ.Tarlov2,MichaelR.Zachariah1,21MechanicalEngineeringDepartment,UniversityofMaryland,CollegePark,Maryland,U.S.A2NationalInstituteofStandardsandTechnology(NIST),Gaithersburg,Maryland,U.S.A

*2:30‐2:50pm MechanismsofPoly(amidoamine)DendrimerTransepithelialTransportandTightJunctionModulationinCaco‐2CellsD.S.Goldberg1,P.W.Swaan1,2andH.Ghandehari1,31FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD,USA2Center for Nanomedicine and Cellular Delivery, Department of Pharmaceutical Sciences,UniversityofMaryland,Baltimore,MD,USA3DepartmentsofPharmaceuticsandPharmaceuticalChemistry&Bioengineering,CenterforNanomedicine,SaltLakeCity,UT,USA

2:50‐3:10pm AbsorbableCoatings:StructureandDrugElutionS.SarkarDas,M.K.McDermott,A.D.Lucas,T.E.Cargal,L.Patel,D.M.Saylor,D.V.PatwardhanFoodandDrugAdministration,CenterforDevicesandRadiologicalHealth,OfficeofScienceand

EngineeringLaboratories,SilverSpring,Maryland,USA

Session20 Saturday,May1 SPECIALTOPICS

1:30‐3:30pm Room: KimBuildingRoom2111

SessionChair: AdamHsieh

FischellDept.ofBioengineering,UniversityofMaryland

*1:30‐1:50pm TelemetricEpilepsyMonitoringandSeizuresAidK.Hameed,F.Azhar,I.Shahrukh,M.Muzammil,M.AamairandD.MujeebSir Syed University of Engineering and Technology Dept of Biomedical Engineering, Karachi,Pakistan

1:50‐2:10pm BiosensingwithSemiconductorQuantumDotsKellyBoeneman, JamesB.Delehanty,DuaneE.Prasuhn,KimihiroSusumu,MichaelH.Stewart,EunkeuOh,AlanL.Huston,IgorL.MedintzU.S.NavalResearchLaboratory

2:10‐2:30pm RelativeRiskofWhiplashinLow‐VelocityCollisionsDuetoDirectionof Impact

S.Kumar,R.Ferrari,andY.NarayanUNT‐HealthScienceCenter/PMI‐OMMDept.,Ft.Worth,Texas

*2:30‐2:50pm SpikeDetectionforIntegratedCircuits:ComparativeStudyA.SarjeandP.AbshireISR/Dept.ofE&C.E.,Univ.ofMaryland,CollegePark,USA

2:50‐3:10pm EffectofAmbientHumidityontheElectricalConductanceofa TitaniumOxideCoatingbeinginvestigatedforPotentialusein Biosensors

JorgeTorres,JamesSweeney,JoseBarretoDept.ofBioengineering,FloridaGulfCoastUniversity

*3:10‐3:30pm BrainComputerInterfaceinCerebellarAtaxiaG.I.Newman1,S.H.Ying2,3,Y.‐S.Choi1,H.‐N.Kim5,A.Presacco1,M.V.Kothare4,N.V.Thakor1,21DepartmentofBiomedicalEngineering,2DepartmentofNeurology,3Ophthalmology,TheJohnsHopkins University School of Medicine, USA, 4Chemical Engineering, Lehigh University, USA,5ElectronicsandElectricalEngineering,PusanNationalUniversity,Korea

*studentpaper underlinedenotespresentingauthor

Session21 Saturday,May1 IMAGING2

1:30‐3:30pm Room: AnimalSci.Bldg.Room0408

SessionCo‐Chairs: JerryWierwilleFishellDept.ofBioengineering,Univ.ofMaryland

IacovosKyprianouU.S.FoodandDrugAdministration

*1:30‐1:50pm ReliabilityofStructuralEquationModelingoftheMotorCortexinRestingStateFunctionalMRIT.Kavallappa1,S.Roys1,A.Roy2,J.Greenspan1,R.Gullapalli1,andA.McMillan11University of Maryland School of Medicine, Department of Diagnostic Radiology & NuclearMedicine,Baltimore,MD2University of Maryland, Baltimore County, Department of Mathematics and Statistics,Catonsville,MD

*1:50‐2:10pm QuantitativeCharacterizationofRadiofrequencyAblationLesionsin TissueUsingOpticalCoherenceTomography

J.Wierwille1,A.McMillan3,R.Gullapalli3,J.Desai2,andY.Chen11DepartmentofBioengineering,2DepartmentofMechanicalEngineering;UniversityofMaryland,CollegePark,USA3DepartmentofRadiology,UniversityofMaryland,Baltimore,USA

2:10‐2:30pm ClinicallyRelevantHandHeldTwoLeadEEGDeviceE.M.O’Brien1andR.L.Elliott21SchoolofEngineering,MercerUniversity,Macon,GA,U.S.A.2SchoolofMedicine,MercerUniversity,Macon,GA,U.S.A.

*2:30‐2:50pm ASimpleStructuralMagneticResonanceImaging(MRI)methodfor3DMappingbetweenHeadSkinTattoosandBrainLandmarksMulugetaSemeworkStateUniversityofNewYork,DownstateMedicalCenter,Brooklyn,USA

2:50‐3:10pm FramepotentialclassificationalgorithmforretinaldataJohnJ.Benedetto1,WojciechCzaja1,MartinEhler1,2

1NorbertWienerCenterforHarmonicAnalysisandApplicationsDepartmentofMathematics,UniversityofMaryland,CollegePark,MD207422NationalInstitutesofHealth,EuniceKennedyShriverNationalInstituteofChildHealthandHumanDevelopmentPPB/LIMB/SMB,Bethesda,MD,20892,USA

*studentpaper underlinedenotespresentingauthor

Session22 Saturday,May1 Biosensors

3:50‐5:50pm Room: KimLectureHallRoom1110

SessionCo‐Chairs: IanWhiteUniversityofMaryland,CollegePark,MD

YordanKostovUniversityofMaryland,BaltimoreCounty

*3:50‐4:10pm ElectrostaticPurificationofNucleicAcidsforMicroTotalAnalysisSystemsE.HoppmannandI.M.WhiteFischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD

*4:10‐4:30pm ApplicabilityofSurfaceEnhancedRamanSpectroscopyforDetermining theConcentrationofAdenineandS‐AdenosylHomocysteineina MicrofluidicSystem

OmarBekdash1,JordanBetz1,YiCheng2andGaryW.Rubloff2,31DepartmentofBioengineering,UniversityofMaryland,CollegePark,MD,USA2InstituteforSystemsResearch,UniversityofMaryland,CollegePark,MD,USA3DepartmentofMaterialsScienceandEngineering,UniversityofMaryland,CollegePark,MD,USA

*4:30‐4:50pm IntegrationofCapillaryRingResonatorBiosensorwithPDMSMicrofluidicsforLabel‐freeBiosensingFarnooshFarahiandIanWhiteUniversityofMaryland,FischellDepartmentofBioengineering

4:50‐5:10pm SurfacePlasmon‐coupledEmissionfromRhodamine‐6GAggregatesfor RatiometricDetectionofEthanolVapors

R.SaiSathish,Y.KostovandG.RaoUniversityofMarylandBaltimoreCounty/CenterforAdvancedSensorTechnologyandDepartmentofChemicalandBiochemicalEngineering,TechnologyResearchCenter,Baltimore,

USA

*5:10‐5:30pm FormationofDendriticSilverSubstratesbyGalvanicDisplacementforSurfaceEnhancedRamanSpectroscopyJordanBetz1,YiCheng2,OmarBekdash1,SusanBuckhout‐White3andGaryW.Rubloff2,31FischellDepartmentofBioengineering,UniversityofMaryland,CollegePark,MD,USA2InstituteforSystemsResearch,UniversityofMaryland,CollegePark,MD,USA3DeptofMaterialsScienceandEngineering,UniversityofMaryland,CollegePark,MD,USA

5:30‐5:50pm HighSpecificityBindingofLectinstoCarbohydrateFunctionalizedEtchedFiberBraggGratingOpticalSensorsGeunminRyu1,MarioDagenais1,MatthewT.Hurley2andPhilipDeShong21DeptofElectricalandComputerEngineering,UniversityofMaryland,CollegePark,MD207422DepartmentofChemistryandBiochemistry,UniversityofMaryland,CollegePark,MD20742

*studentpaper underlinedenotespresentingauthor

Session23 Saturday,May1 CANCER

3:50‐5:50pm Room: KayBoardKimRoom1111

SessionCo‐Chairs: AnuPuri

CenterforCancerResearch,NCI‐Frederick,MDKshitijGuptaCenterforCancerResearch,NCI‐Frederick,MD

*3:50‐4:10pm DrugResistanceAlwaysDependsontheTurnoverRateC.TomasettiandD.LevyDepartmentofMathematicsandCenterforScientificComputationandMathematicalModeling(CSCAMM),UniversityofMaryland,CollegePark,MD,USA

4:10‐4:30pm DesignandExVivoEvaluationofa3DHighIntensityFocusedUltrasoundSystemforTumorTreatmentwithTissueAblationK.Lweesy,L.Fraiwan,M.Al‐Shalabi,L.Mohammad,andR.Al‐OglahJordan University of Science and Technology, Faculty of Engineering, Biomedical EngineeringDepartment,Irbid22110,Jordan

4:30‐4:50pm NanoparticleMediatedTargetingofAlpha4Beta1IntegrinExpressingCellsforLymphomaTreatmentKshitijGupta,XueZhiZhao,JoshuaDThomas,AnuPuri,TerrenceRBurke,RobertBlumenthalMembraneStructureandFunctionSection,NanobiologyProgram,CenterforCancerResearch,NCI‐Frederick,Frederick,MD,USA

4:50‐5:10pm DesignandDevelopmentofaNovelClassofLight‐SensitiveLiposomesforSustainedandTriggered(Localized)DeliveryofCancerTherapeuticsAnuPuri,AmichaiYavlovich,AlokSingh,RobertBlumenthalMembraneStructureandFunctionSection,NanobiologyProgram,CenterforCancerResearch,NCI‐Frederick,Frederick,MD,USA

*studentpaper underlinedenotespresentingauthor

Session24 Saturday,May1 OXIMETRY

3:50‐5:50pm Room: KayBoardKimRoom1107

SessionCo‐Chairs: JessicaC.Ramella‐Roman TheCatholicUniversityofAmerica,WashingtonDC

GaneshSriramDept.ofChem.andBiomolecularEngineering,Univ.ofMaryland

*3:50‐4:10pm MonitoringandControllingOxygenLevelsinMicrofluidicDevicesPeterC.Thomas

1,2,SrinivasaR.Raghavan

3andSamuelP.Forry

1

1NationalInstituteofStandardandTechnology/BiochemicalScienceDivision,Gaithersburg,MD

2UniversityofMaryland/FischellDepartmentofBioengineering,CollegePark,MD

3UniversityofMaryland/DeptofChemicalandBiomolecularEngineering,CollegePark,MD

*4:10‐4:30pm AnImagingPulseOximeterBasedonaMulti‐ApertureCameraAliBasiri1,JessicaC.Ramella‐Roman11TheCatholicUniversityofAmerica,620MichiganAve.,N.E.,WashingtonDC,USA

*4:30‐4:50pm FluorescentMicroparticlesforSensingCellMicroenvironmentOxygenLevelswithin3DScaffoldsMiguelA.AcostaandJennieB.LeachUniversityofMarylandBaltimoreCounty,DepartmentofChemicalandBiochemicalEngineering;1000HilltopCircle,ECS#314,Baltimore,MD21250

*4:50‐5:10pm DeterminationofInVivoBloodOxygenSaturationandBloodVolumeFractionusingDiffuseReflectanceSpectroscopyP.ChenandW.LinDepartmentofBiomedicalEngineering,FloridaInternationalUniversity,Miami,USA

*studentpaper underlinedenotespresentingauthor

Session25 Saturday,May1 ImageAnalysis

3:50‐5:50pm Room: PepcoSeminarKimRoom1105

SessionCo‐Chairs: JohnJ.BenedettoNorbertWienerCenter,DepartmentofMathematics,UniversityofMarylandWojciechCzajaNorbertWienerCenter,DepartmentofMathematics,UniversityofMaryland

3:50‐4:10pm FredholmIntegralEquationsinBiophysicalDataAnalysisP.SchuckDynamicsofMacromolecularAssembly,LBPS,NIBIB,NIH,Bethesda,MDUSA

4:10‐4:30pm High‐ResolutionAutofluorescenceImagingforMapping MolecularProcesseswithintheHumanRetinaMartinEhler1,2,ZigurtsMajumdar1,EmilyKing1,2,JuliaDobrosotskaya2,EmilyChew3,WaiWong3,DeniseCunningham3,WojciechCzaja2,RobertF.Bonner11National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health andHumanDevelopment,PPB/LIMB/SMB,Bethesda,USA2UniversityofMaryland,MathematicsDepartment,CollegePark,USA3NationalInstitutesofHealth,NationalEyeInstitute,Bethesda,USA

4:30‐4:50pm LocalHistogramsforClassifyingH&EStainedTissuesM.L.Massar1,R.Bhagavatula2,M.Fickus1andJ.Kovačević2,31DeptofMathematicsandStatistics,AirForceInstofTech,WrightPattersonAirForceBase,USA2DeptofElectricalandComputerEngineering,CarnegieMellonUniversity,Pittsburgh,USA3DepartmentofBiomedicalEngineering,CarnegieMellonUniversity,Pittsburgh,USA

4:50‐5:10pm DetectingandClassifyingCancersfromImageDatausing OptimalTransportation

G.K.Rohde1,W.Wang1,D.Slepcev2,A.B.Lee3,C.Chen1,andJ.A.Ozolek4 1CenterforBioimageInformatics,BiomedicalEngineeringDepartment,CarnegieMellon University,Pittsburgh,USA 2DeptofMathematicalSciences,3DeptofStatistics,CarnegieMellonUniversity,Pittsburgh,USA 4DepartmentofPathology,Children'sHospitalofPittsburgh,Pittsburgh,USA

5:10‐5:30pm NanoscaleImagingofChemicalElementsinBiomedicine MariaA.Aronova1,YoungchanKim2,AliosckaA.Sousa1,GuofengZhang1,

RichardD.Leapman1

1NationalInstitutesofHealth,NIBIB,Bethesda,USA 2CenterforComputationalMaterialsScience,NavalResearchLaboratory,WashingtonDC,USA

5:30‐5:50pm SparseRepresentationandVariationalMethodsinRetinalImage Processing J.Dobrosotskaya1,M.Ehler1,2,E.King1,2,R.Bonner2,W.Czaja1

1NorbertWienerCenterforHarmonicAnalysisandApplicationsDepartmentofMathematics,UniversityofMaryland,CollegePark,USA

2NationalInstitutesofHealth,EuniceKennedyShriverNationalInstituteofChildHealth andHumanDevelopment,PPB/LIMB/SMB,Bethesda,USA*studentpaper underlinedenotespresentingauthor

Session26 Saturday,May2 Neuromechanics&Rehabilitation

3:50‐5:30pm Room: KimBuildingRoom2111

SessionCo‐Chairs: JaeKunShimDepartmentofKinesiology,UniversityofMarylandBrianBaumDepartmentofKinesiology,Univ.ofMaryland

*3:50‐4:10pm StabilizingEffectsofVisualFeedbackduringLocomotionJasonGreen,RussellRosenberg,HenryFleming,EricAnson,JohnJekaDepartmentofKinesiology,UniversityofMaryland,CollegePark,MD

*4:10‐4:30pm Posture‐LocomotorInteractionsarenotEquivalentintheAPandML Directions

EricAnson1,PeterAgada1,TimKiemel1,YuriIvanenko2,FrancescoLacquaniti2,JohnJeka11DepartmentofKinesiology,UniversityofMaryland,CollegePark,MD2LaboratoryofHumanPhysiology,FondazioneSantaLucia,Rome,Italy

*4:30‐4:50pm OptimizationandValidationofaBiomechanicalModelforAnalyzing Running‐SpecificProstheses

BrianS.Baum1,RoozbehBorjian1,You‐SinKim1,AlisonLinberg1,andJaeKunShim1,2,31DepartmentofKinesiology,UniversityofMaryland,CollegePark,MDUSA2DepartmentofBioengineering,UniversityofMaryland,CollegePark,MDUSA3NeuroscienceandCognitiveScience(NACS)GraduateProgram,UniversityofMaryland,College

Park,MDUSA

*4:50‐5:10pm Multi‐FingerSynergiesduringIsometricForceProductionTaskinIndex FingerAmputees

SohitKarol,JaeKunShimDepartmentofKinesiology,UniversityofMaryland,CollegePark,MD

*5:10‐5:30pm PrehensionSynergy:UseofMechanicalAdvantageduringMulti‐Finger TorqueProductiononMechanicallyFixed‐andFree‐Object

JaebumPark1,2,You‐SinKim2,BrianS.Baum2,YoonHyukKim5andJaeKunShim2,3,4,51DepartmentofKinesiology,ThePennsylvaniaStateUniversity,UniversityPark,USA2DepartmentofKinesiology,UniversityofMaryland,CollegePark,USA3DepartmentofBioengineering,UniversityofMaryland,CollegePark,MD207424NeuroscienceandCognitiveScience(NACS)GraduateProgram,UniversityofMaryland,CollegePark,MD207425DepartmentofMechanicalEngineering,KyungHeeUniversity,GlobalCampus,Korea130‐701

*studentpaper underlinedenotespresentingauthor

Session27 Saturday,May2 MODELING,OPTIMIZINGANDMONITORING

3:50‐5:30pm Room: AnimalSci.Bldg.Room0408

SessionChair: KuroshDarvish TempleUniversity,Philadelphia,PA

*3:50‐4:10pmModelingtheTraumaticAorticRupture MehdiShafieian,KuroshDarvish TempleUniversity,Philadelphia,PA

4:10‐4:30pm OscillatingPressureExperimentsonPorcineAortaVasilyRomanov,SoroushAssari,KuroshDarvishTempleUniversity,Philadelphia,PA

4:30‐4:50pm Quasi‐StaticAnalysisofElectricFieldDistributionsbyDiscElectrodesinaRabbitEyeModelS.Minnikanti1,E.Cohen2andN.Peixoto11ElectricalandComputerEngineering,GeorgeMasonUniversity,Fairfax,VA,USA2DivisionofPhysics,FoodandDrugAdministration,SilverSpring,MD,USA

*4:50‐5:10pm OptimizingtheGeometryofDeepBrainStimulatingElectrodes J.Y.ZhangandW.M.Grill

DepartmentofBiomedicalEngineering,DukeUniversity,Durham,NC,USA

*5:10‐5:30pm ExploratoryParcellationoffMRIDataBasedonFiniteMixtureModelsandSelf‐AnnealingExpectationMaximizationS.MalekiBalajoo1,G.A.Hossein‐Zadeh1andH.Soltanian‐Zadeh1,21ControlandIntelligentProcessingCenterofExcellence,SchoolofElectricalandComputerEngineering,UniversityofTehran,Tehran14395‐515,Iran.2ImageAnalysisLaboratory,RadiologyDepartment,HenryFordHealthSystem,Detroit,MI48202,USA.

*studentpaper underlinedenotespresentingauthor

Session28 Sunday,May2 BIOMATERIALS2

9:00‐11:00am Room: KayBoardRoom,KimRm1111

SessionCo‐Chairs: JoonilSeogFischellDept.ofBioengineering,Univ.ofMaryland

MarianaMeyerFischellDept.ofBioengineering,Univ.ofMaryland

*9:00‐9:20am IdentificationofBacteriaandSterilizationofCrustaceanExoskeletonusedasaBiomaterial

TiffanyOmokanwaye1,DonaeOwens2,andOttoWilson,Jr.1 1CatholicUniversityofAmerica/BiomedicalEngineeringDepartment,Washington,D.C.,USA 2BenjaminBannekerAcademicHighSchool,Washington,D.C.,USA

*9:20‐9:40am NeuralStemCellDifferentiationin2Dand3DMicroenvironmentsA.S.Ribeiro1,E.M.Powell2andJ.B.Leach11University of Maryland Baltimore County/Chemical & Biochemical Engineering, Baltimore,USA2UniversityofMarylandSchoolofMedicine/AnatomyandNeurobiology,Baltimore,USA

*9:40‐10:00am AMicrofluidicPlatformforOpticalMonitoringofBacterialBiofilms M.T.Meyer1,2,V.Roy1,3,W.E.Bentley1,andR.Ghodssi1,2,4

1Fischell Department of Bioengineering, 2Institute for Systems Research, 3Department ofMolecularandCellBiology,4DepartmentofElectricalandComputerEngineering,UniversityofMarylandCollegePark,CollegeParkMD,USA

10:00‐10:20am ConductionPropertiesofDecellularizedNerveBiomaterialsM.G. Urbanchek1, B.S. Shim2, Z. Baghmanli1, B. Wei1, K. Schroeder3, N.B. Langhals1, R.M.Miriani1,B.M.Egeland1,D.R.Kipke1,D.C.Martin2,P.S.Cederna11UniversityofMichigan/Surgery,PlasticSurgery,AnnArbor,USA2UniversityofDelaware/MaterialsScience&Engineering,Newark,USA3HopeCollege/Literature,Science,andtheArts,Holland,USA

10:20‐10:40am Radio‐opacificationofCalciumPhosphate(CaP)CementforSpinal Augmentation:CadavericandBiomechanicalStudy

Michael Gerling, Nasim Chowdhury, Neel Shah, David Ross, Alexandra Carrer, Nael Shanti,SabetHajeer,DanielLevin,SrinivasKolla,ScottLehto,EdwardChay,SubrataSahaSUNYDownstateMedicalCenter

10:40‐11:00am ReverseCholesterolTransport(RCT)ModelingwithIntegratedSoftwareConfiguratorS.Adhikari

SysoftCenterforSystemsBiologyandBioengineering,WhitehouseStation,NJ

*studentpaper underlinedenotespresentingauthor

Session29 Sunday,May2 BIOMECHANICS

9:00‐11:00am Room: KayBoardRoom,KimRm1107

SessionCo‐Chairs: KuroshDarvish TempleUniversity,Philadelphia,PA AliSadegh CityCollegeofNewYork,NewYork,NY

9:00‐9:20am EvaluatingBrainStrainandStressinLinearHeadImpact KavehLaksari,SoroushAssari,KuroshDarvish TempleUniversity

9:20‐9:40am MechanicsofCSFFlowthroughTrabecularArchitectureintheBrainParisaSaboori,CatherineGermanierandAliSadeghDeptofMechanicalEngineering,TheCityCollegeofTheCityUniversityofNewYork

9:40‐10:00am ImpactofMechanicalLoadingtoNormalandAneurysmalCerebral Arteries

M.Zoghi‐Moghadam,P.SabooriandA.SadeghDepartmentofMechanicalEngineering,CityCollegeofNewYork,NewYork,NY

10:00‐10:20am IdentificationofMaterialPropertiesofHumanBrainunderLargeShearDeformation:AnalyticalVersusFiniteElementApproachC.D.Untaroiu1,Q.Zhang1,A.M.Damon1,J.R.Crandall1,K.Darvish2,G.Paskoff3andB.S.Shender31CenterforAppliedBiomechanics/DepartmentofMechanical&AerospaceEngineering,UniversityofVirginia,Charlottesville,VA,USA2DepartmentofMechanicalEngineering,TempleUniversity,Philadelphia,PA,USA3NavalAirWarfareCenterAircraftDivision,PatuxentRiver,MD,USA

10:20‐10:40am MechanismsofTraumaticRuptureoftheAorta:RecentMultiscaleInvestigations

NicholasA.White1,ChiragS.Shah2,WarrenN.Hardy11VirginiaTech–WakeForestUniversity,CenterforInjuryBiomechanics,Blacksburg,USA2FirstTechnologySafetySystems,Inc.,CAE,Plymouth,USA

10:40‐11:00am HeadImpactResponse:PressureAnalysisSimulationR.T.Cotton1,P.G.Young2,C.W.Pearce2,L.Beldie3,B.Walker31TechnicalServices,Simpleware,Exeter,UK2SchoolofEngineering,MathematicsandPhysicalSciences,UniversityofExeter,Exeter,UK3VehicleDesign,ARUP,Solihull,UK

*studentpaper underlinedenotespresentingauthor

Session30 Sunday,May2 IMAGING3

9:00‐11:00am Room: PepcoSeminarRoom,KimRm1105

SessionCo‐Chairs: BruceYuFischellDept.ofBioengineering,UniversityofMaryland

A.J.Jin NationalInstituteofBiomedicalImagingandBioengineering,NIH,USA

9:00‐9:20am Raman‐AFMInstrumentationandCharacterizationofSERSSubstratesandCarbonNanotubesQ.Vu1,M.H.Zhao1,2,E.Wellner1,X.Truong1,P.D.Smith1,A.J.Jin1,*1LaboratoryofBioengineeringandPhysicalScience,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,MD20892,USA2Building & Fire Research Laboratory, National Institute of Standards and Technology,Gaithersburg,MD20899,USA

*9:20‐9:40am ANovelModelofSkinElectricalInjuryThuT.A.Nguyen1,AliBasiri1,J.W.Shupp2,A.R.Pavlovich2,M.H.Jordan2,Z.Sanford2,andJ.C.Ramella‐Roman11TheCatholicUniversityofAmerica,620MichiganAve.,N.E.,WashingtonDC,USA.2TheBurnCenter,WashingtonHospitalCenter,WashingtonDC,USA

9:40‐10:00am Design,Construction,andEvaluationofanElectricalImpedance Myographer

K.Lweesy,L.Fraiwan,D.Hadarees,A.Jamil,andE.RamadanJordanUniversityofScienceandTechnology,FacultyofEngineering,BiomedicalEngineeringDepartment,Irbid22110,Jordan

10:00‐10:20am 19FIT:AclassofImagingImagentsfor19FMRIZhong‐xingJiang,XinLiu,Eun‐KeeJeong,YihuaBruceYUPharmacySchool,UniversityofMarylandatBaltimore

*studentpaper underlinedenotespresentingauthor

Session31 Sunday,May2 HARDTISSUEANDPOSTURE

9:00‐11:00am Room: KimBuildingRoom2111

SessionCo‐Chairs: SubrataSaha SUNYDownstateMedicalCenter,Brooklyn,NewYork ShervinMajd ESRA,Olney,Maryland

9:00‐9:20am OptimizationofScrewPositioninginMandibleduringBilateralSagittal SplitOsteotomyUsingFiniteElementMethod

A.RaeisiNajafi1,A.Pashaei2,S.Majd3,I.ZoljanahiOskui4,B.Bohluli51Departmentof IndustrialandEnterpriseSystemsEngineering,Universityof IllinoisatUrbana‐Champaign,IL2CISTIB,DepartmentofTechnology,UniversityofPompeuFabra,Barcelona,Spain3EngineeringandScientificResearchAssociates,3616MartinsDairyCircle,20832,Olney,MD4DepartmentofBiomedicalEngineering,AmirkabirUniversityofTechnology,Tehran,Iran5DepartmentofOralandMaxillofacialSurgery,AzadSchoolofDentistry,Tehran,Iran

*9:20‐9:40am ExtractionandCharacterizationofaSolubleChickenBoneCollagenTiffanyOmokanwaye,OttoWilson,Jr.,HodaIravaniandPramodhKariyawasamCatholicUniversityofAmerica/BiomedicalEngineeringDepartment,Washington,D.C.,USA

*9:40‐10:00amEffectofDeformationRateontheFlexuralFractureBehaviorofHuman Ribs

SubrataSaha,GavrielFeuerDepartment of Orthopedic Surgery and Rehabilitation Medicine, SUNY Downstate MedicalCenter,Brooklyn,NewYork11203

10:00‐10:20am AModelforHumanPosturalRegulationYaoLiandWilliamS.LevineDepartmentofElectricalandComputerEngineering,UniversityofMaryland,CollegePark,USA

10:20‐10:40am DevelopmentofanAverageChestShapeforObjectiveEvaluationofthe AestheticOutcomeintheNussProcedurePlanningProcess

K.J.Rechowicz1,R.Kelly2,M.Goretsky2,F.Frantz2,S.Knisley3,D.Nuss2andF.D.McKenzie11DepartmentofModelingandSimulation,OldDominionUniversity,Norfolk,VA23529,USA2DepartmentofSurgery,EasternVirginiaMedicalSchool,Norfolk,VA23507,USA3DepartmentofMechanicalEngineering,OldDominionUniversity,Norfolk,VA23529,USA

*studentpaper underlinedenotespresentingauthor

Session32 Sunday,May2 SICKLECELLANDBLOODCELL

9:00‐11:00am Room: AnimalScienceBuilding,Rm.0408

SessionCo‐Chairs: LewisHsuPediatric Hematology, Children's National Medical Center, Washington DC Frank Ferrone Department of Physics, Drexel University, Philadelphia, PA

*9:00‐9:20am SickleHemoglobinFiberGrowthRatesRevealedbyOpticalPattern

GenerationZ.Liu,A.Aprelev,M.Zakharov,andF.A.FerroneDrexelUniversity,DepartmentofPhysics,Philadelphia,PA,USA

*9:20‐9:40am SickleCellOcclusioninMicrochannelsA.Aprelev1,W.Stephenson1,H.Noh2,M.Meier3,M.MacDermott3,N.Lerner3,andF.A.Ferrone11DrexelUniversity,DepartmentofPhysics,Philadelphia,PA,USA2DrexelUniversity,DepartmentofMechanicalEngineeringandMechanics,Philadelphia,PA,USA3Marian Anderson Sickle Cell Center, St. Christopher’s Hospital for Children, Philadelphia, PA,USA

*9:40‐10:00am EngineeringMicrofluidicsbasedTechnologiesforRapidSortingofWhiteBloodCells

VinayRaj1,KranthiKumarBhavanam2,VahidrezaParichehreh2andPalaniappanSethu2 1DuPontManualHighSchool,Louisville,KY40208,USA 2DepartmentofBioengineering,UniversityofLouisville,Louisville,KY40208,USA

10:00‐10:20am PeripheralArterialTonometryinassessingEndothelialDysfunctionin PediatricSickleCellDisease

K.M.Sivamurthy1,C.Dampier2,M.MacDermott1,M.Meier1,M.Cahill1,andL.L.Hsu31Hematology,St.Christopher’sHospitalforChildren,Philadelphia,PA,USA2EmoryUniversity,Atlanta,GA,USA.3Hematology,Children’sNationalMedicalCenter,Washington,DCUSA

10:20‐10:40am DynamicsofCapsulesandEruthrocytesinMicrofluidicChannelsand VascularMicrovessels

PanagiotisDimitrakopoulos,ShugiKuriakose,WalterR.DodsonIIIDept.ofChemicalandBiomoleculerEngineering,Univ.ofMaryland

10:40‐11:00am ComparisonofShearStress,ResidenceTimeandLagrangianEstimatesofHemolysisinDifferentVentricularAssistDevicesK.H.Fraser,M.E.Taskin,T.Zhang,B.P.GriffithandZ.J.WuArtificialOrgansLaboratory,Dept.ofSurgery,UniversityofMarylandMedicalSchool,Baltimore,USA

*studentpaper underlinedenotespresentingauthor

Session33 Sunday,May2

TheDr.JamesW.JacobsonSymposiumonTechnologiesforCancerDiagnostics

9:00‐12:45pm Room: KimLectureHall,KimBuildingRm.1110

SessionCo‐Chairs: JohnJessup NationalCancerInstitute,Rockville,MD

AvrahamRasooly NationalCancerInstitute,Rockville,MD

9:00‐9:30am ChallengesforcancerdiagnosticsJohnJessupNationalCancerInstitute,Rockville,MD

9:30‐9:50am ClinicalApplicationsofMultispectralImagingFlowCytometryH.Minderman1,T.C.George2,K.L.O’Loughlin1andP.K.Wallace11RoswellParkCancerInstitute,FlowandImageCytometryFacility,Buffalo,USA2AmnisCorporation,Seattle,USA

9:50‐10:10am MultispectralImaging,ImageAnalysis,andPathologyRichardM.LevensonBrightonConsultingGroup,Principal,Brighton,MA,USA

10:10‐10:30am SensitiveCharacterizationofCirculatingTumorCellsforImproving TherapySelection

H.BenHsieh1,GeorgeSomlo2,RobynBennis1,PaulFrankel2,RobertT.Krivacic1,SeanLau2,JaneyLy1,ErichSchwartz3,andRichardH.Bruce11PaloAltoResearchCenter/BiomedicalEngineering,PaloAlto,CA2CityofHopeCancerCenter/MedicalOncology,Duarte,CA3StanfordUniversity/DepartmentofMedicine,Stanford,CA

10:30‐10:45am CoffeeBreak

10:45‐11:05am ImmunoassaysontheBioCDforCancerBiomarkers:Sensitivityand Scalability DavidNolte PurdueUniversity,DepartmentofPhysics,WestLafayette,IN

11:05‐11:25am NanoholeArraySensorTechnology:MultiplexedLabel‐FreeProtein BindingAssays

J.Cuiffi1,R.Soong2,S.Manolakos1,S.Mohapatra3,andD.Larson21DraperLaboratory–BioengineeringCenteratUSF,Tampa2DraperLaboratory,Cambridge3UniversityofSouthFlorida,DepartmentofMolecularMedicine,Tampa

11:25‐11:45am MolecularProfilingofRareCirculatingTumorCellsinPeripheralBloodUsingMicrofluidicsStevenSoper

LouisianaStateUniversity,DepartmentofChemistry,BatonRouge,LA,

11:45am‐12:05 IntegratedBiochipSensorsforDetectionofCancer RashidBashir PurdueUniversity,BirckNanotechnologyCenter,WestLafayette,IN

12:05‐12:25 ClinicalMicrofluidicsforCTCanalysisMehmetTonerSurgicalServicesandBioMEMSResourceCenter,MassachusettsGeneralHospital,HarvardMedicalSchool,andShrinersHospitalforChildren,Boston,MA

12:25‐12:45 NCIfundingopportunitiesfortechnologydevelopmentAvrahamRasoolyNationalCancerInstitute,Rockville,MD