Towards Translational Research Community

LIFETIME RISK OF DEVELOPING OR DYING FROM CANCER

US National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) Database

42.05

37.58

22.6219.13

Males Females Males Females

Risk of developing Risk of dying from

%

1/25

Credit: National Cancer Institute

wouldn’t

PRECISIONbe better?

chrom position ref Trairak type subtype gene rsids clinvardiseasename

chr1 45797759 T C snp ts MUTYH rs77542170 MYH-associatedpolyposis|Hereditarycancer-

chr2 242799 T C snp ts SH3YL1 rs10181051 -

chr3 239554 C CT indel ins CHL1 rs58240971 -

chr4 1090624 G A snp ts RNF212 rs4045481 -

chr5 256482 CTT C indel del SDHA rs112307877 -

chr6 7542147 C CA indel ins DSP rs17133512 Cardiomyopathy

chr7 128578300 G T snp tv IRF5 rs2004640 Systemiclupuserythematosus|Rheumatoidarthritis

chr8 19819723 C G snp tv LPL rs328 LIPOPROTEINLIPASEPOLYMORPHISM

chr9 18826260 GT G indel del ADAMTSL1 rs35525189 -

chr10 1142207 T C snp ts WDR37 rs10794716 -

chr11 6630027 TC T indel del ILK rs11314683 Cardiomyopathy

chr12 113357192 G A snp ts OAS1 rs10774671 Diabetesmellitus,type1,susceptibilityto

chr13 21729289 C

CAGTTTTCTTTGTTGCTGACATCTCGGATGTTCTGT

CCATGTTTAAGGAACCTTT indel ins SKA3 - -

chr14 20470851 CT C indel del OR4Q2 rs34315947 -

chr15 23609549 G T snp tv GOLGA8S rs140059935 -

chr16 138771 A AG indel ins NPRL3 rs397815833 -

chr17 3594275 TG T indel del P2RX5 rs3215407 -

chr18 690701 A AAGCTGTTTCCCCTGGAGAGTCC indel ins ENOSF1 rs145372402 -

chr19 1534041 T C snp ts PLK5 rs10853954 -

chr20 3026344 A AGCCCC indel ins GNRH2 rs16996832 -

chr21 10906993 CT C indel del TPTE - -

chr22 16350244 C A snp tv NF1P6 rs2905295 -

chrX 2833604 C T snp ts ARSD rs111939179 -

Systems Biology Institutes Around the World

http://en.wikipedia.org/wiki/List_of_systems_biology_research_groups