18th INTERNATIONAL SYMPOSIUM ON ADULT CONGENITAL HEART DISEASE

CONGENITAL HEART DISEASE & BEYOND 2008

TORONTO – June 4 – 7, 2008

THE FOUR SEASONS HOTEL, YORKVILLE

TABLE OF CONTENTS Course Information, Course Objectives, Conference Facility, Accreditation, Cancellation & Refund Policy ……………………………………………… Section 1 Program ……………………………………………………………………... Section 2 Setting the Scene ……………………………………………………………. Section 3 Arrhythmias: A burden in ACHD Simultaneous Break out Sessions (afternoon) The Dilating Aorta: What Really Matters Pregnancy ……………………………………………………………………. Section 4 Simultaneous Break Out Sessions (morning) Simultaneous Break Out Sessions (afternoon) Original Oral Poster Presentation (#2,3) The Failing Heart Pulmonary Hypertension in ACHD …………………………………………. Section 5 Simultaneous Break Out Sessions (morning) Timing and Strategies for Interventions Challenges of the Fontan Circulation: Any Solution? Original Oral Poster Presentation in ACHD (#1) Challenges in the Care of Adults with CHD …………………………………. Section 6 Dr. Bill Williams Lecture Debates Faculty Members ……………………………………………………………... Section 7 Registration Form …………………………………………………………….. Section 8 Sponsors ……………………………………………………………………… Section 9 Endorsements ………………………………………………………………… Section 10 General Course Evaluation ……………………………………………………Section 11

Course Information This Symposium is a unique forum where medical professionals can meet their colleagues from around the world, and exchange ideas and information in the field of Adult Congenital Heart Disease.

International faculty and attendees have gathered annually to educate, learn and receive updates about the latest innovations in diagnosis and management for Adult Congenital Heart Disease. This symposium features a highly dedicated academic international faculty team which includes speakers from the Oregon Health Sciences University, University of Pennsylvania School of Medicine and the University of Toronto.

I expect the Symposium to provide the best of science and education in this area of practice. The Program is designed for all healthcare professionals working with Adult Congenital Heart Disease (ACHD) and should familiarize participants with the latest clinical information on the diagnosis and management for ACHD. Nursing will also have a major organizational and educational role within this Program.

Course Objectives

At the completion of the symposium, participants will be able to:

• Integrate basic knowledge on the anatomy and physiology of adult congenital heart disease; • Understand the long-term complications and outcomes in adults with congenital heart disease; • Recognize congenital heart disease as a chronic disease from childhood into adulthood; • Formulate a rational approach to the diagnosis and treatment of adults with congenital heart disease; • Utilize up-to-date treatment strategies; • Be able to do a risk stratification for pregnancies in women with congenital heart disease; • Recognize the importance of a systematic, multidisciplinary team approach to provide excellent care

for adults with congenital heart disease; • Appreciate participation in a network of centers with expertise in congenital heart disease; • Appreciate the important role of advanced nurses in providing comprehensive care for adults with

congenital heart disease; • Recognize the increasing need in human resources and infrastructure to cope with the increasing

population of adults with congenital heart disease

Conference Facility

Participants are responsible for making their own reservations. We have reserved room blocks with reduced rates at Four Seasons Hotel. To secure your room at Four Season Hotel, please call at +1 416-964-0411 and ask to be transferred to the reservation department. Please indicate that you are a participant of The 18th International Symposium on Adult Congenital Heart Disease to get you discount rates. Special rates are available before April 25, 2008.

In the chic heart of Yorkville, steps from designer shops and minutes from theatres, museums and concert halls, the Four Seasons treats visitors to award-winning service and luxurious comfort. The 380 elegant guest rooms, including 150 suites, have a luxurious residential feeling, rendered in custom fabrics and furnishings.

Four Seasons Hotel 21 Avenue Rd, Toronto ON, M5R2G1 Phone: 416 964 0411 Fax. 416 964 2301 www.fourseasons.com/toronto/

Room Rates:

The group rate is $ 285.00.Canadian for single/double per night. A 5% Provincial Sales tax, a 3% Destination Marketing Fee and a 5% Goods and Services tax (GST) will be applied to these rates. A $50.00 charge will apply for each additional adult; there will be no additional charge for children under the age of 18 in parents room. The hotel room block will be held until April 25, 2008, but it may be sold out before this date. After April 25, 2008, reservations will be accepted according to space and rate availability. Therefore, we advise you to register for the program and reserve your hotel room as soon as possible. When you make your reservations, please be sure to ask about any early departure fees or cancellation penalties.

You are free to make your reservation at any other hotel in Downtown Toronto.

June is a popular month for conventions and travelers to Toronto, so we encourage you to take advantage of the special prices offered for the reserved rooms as soon as possible. Room availability after the cut-off date is on a first-come, first-served basis.

Accreditation Statement This event is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada. (Maximum hours to be claimed is 27) This program has been reviewed and approved by the:

"An application for contact hours has been submitted to the Pennsylvania State Nurses Association. " Cancellation and Refund Policy

The Organizing Committee reserves the right to cancel or postpone this Symposium due to any unforeseen circumstances. In the event of cancellation or postponement, the Organization Committee will refund any registration fees, but it is not responsible for any related costs, charges or expenses to participants, including cancellation charges assessed by airlines/travel agencies. Requests for refunds for cancellations by the registrants must be sent in written form before May 1, 2008 in order to get 50% of the registration fees refunded. Cancellations after this date are not refundable. However, registration may be transferred to another person, at no extra charge. Please inform if you plan to send a deputy.

Wednesday June 4th 2008 7:00 am – 7:45 am Registration and Continental Breakfast 8:00 am – 5:30 pm Posters on Display – (room TBA) 7:45 am – 8:00 am Welcome – Opening Comments

Peter Liu, MD Erwin Oechslin, MD 8:00 am to 10:00 am Setting the Scene Chairperson: Erwin Oechslin, MD

• From a patient’s perspective: A lifetime of memories and lessons John MacEachern, President CCHA

• Adult congenital surgeon’s lessons

William Williams, MD

• ACHD in North America: transcending borders Gary Webb, MD

• The ACHD tsunami: implications for the future of the health care system Ariane Marelli, MD

10:00 am – 10:30 am (Break) 10:30 am – 12:30 pm Arrhythmias: A burden in ACHD Chairperson: Louise Harris, MB ChB

• Role of anti-arrhythmics in the era of ablation and devices Joachim Hebe, MD

• Ablation in ACHD

Vijay Chauhan, MD

• Risk stratification for SCD in ACHD Louise Harris, MB ChB

• Devices: PPM, ICD in ACHD

Paul Khairy, MD 12:30 pm – 1:30 pm (Lunch)

Register

online at

www.uhn.ca/ACHDConference2008.asp

1:30 pm – 3:00 pm (Simultaneous Break Out Sessions) Session I: Meet the Expert Session Session II: Meet the Expert Session Why do I? Quality of Life & Palliative Care/End of Life Moderator: Lee Benson, MD Moderator: Adrienne Kovacs, PhD Close an ASD in a 65 year old patient? “When is enough, enough? Ethical issues in adult Gruschen Veldtman, MD congenital heart patients Linda Wright, RN Dilate/stent pulmonary artery stenosis? Felix Berger, MD Palliative does not necessarily mean “terminal” Jeanine Harrison, RN Dilate/stent aortic coarctation? Eric Horlick, MD End of life care: medical management and beyond Christine Newman, MD Why do I celebrate my favorite/tough case? Contribution from the Audience Session III: How To Session Session IV: Meet the Expert Session Noninvasive Diagnostic Tools – Tips & Tricks Diagnostic Advances – Do They Matter in CHD? Moderator: Annie Dore, MD Moderator: Narinder Paul, MD ECG Echocardiography (3-D-echo) Ariane Marelli, MD David Sahn, MD Chest X-ray Cardiac MRI Joseph Perloff, MD Rachel Wald, MD Segmental approach by echocardiography Cardiac CT Erwin Oechslin, MD Yves Provost, MD Nuclear Cardiology Mark Iwanochko, MD 3:00 pm – 3:30 pm (Break) 3:30 pm – 5:30 pm The Dilating Aorta: What Really Matters Chairperson: Anji Yetman, MD

• Is it Marfan Syndrome? Timothy Bradley, MD

• Is it dilating too fast?

Barbara Mulder, MD

• Whom are you going to treat: mouse or man? Anji Yetman, MD

• Surgical treatment of aortic root aneurysm in patients with Marfan syndrome

Tirone David, MD 5:30 pm (Adjourn)

Thursday June 5th 2008 7:00 am – 8:00 am Continental Breakfast 8:00 am – 5:30 pm Posters on Display (room TBA) 8:00 am – 10:00 am Pregnancy Chairperson: Helmut Baumgartner, MD

• How to risk stratify Samuel Siu, MD

• Be proactive and not reactive!

Matthew Sermer, MD

• Anesthesia – does it matter? Eric Goldszmidt, MD

• Risk Stratification and Management

• Fontan - Carole Warnes, MD • Mustard – Jolien Roos-Hesselink, MD • Aortic valvular stenosis – Candice Silversides, MD

10:00 am – 10:30 am (Break) 10:30 am – 12:00 pm (Simultaneous Breakout Sessions)

Session I: How To Session Session II: Meet the Expert Session Pregnancy: Some Tough Questions Cyanotic CHD – A Multi-System Disorder Moderator: Samuel Siu, MD Moderator: Judith Therrien, MD How do you counsel a woman who needs/has a prosthetic The iron story valve? Craig Broberg, MD Jack Colman, MD

Preventive measures How do you choose an anticoagulant and monitor Erwin Oechslin, MD anticoagulation during pregnancy? Carole Warnes, MD To anticoagulate or not to anticoagulate? Craig Broberg, MD How do you counsel a woman with a dilated aorta? Jolien Roos-Hesselink, MD The extra and intra pulmonary arteries – distinctive radiologic features How do you select contraception? Joseph Perloff, MD Candice Silversides, MD Session III: Meet the Expert Session Session IV: Nursing Break Out Session: Clinical Arrhythmias: Device Therapy Moderator: Desiree Fleck, RN Moderator: Robert Hamilton, MD Repaired Tetralogy of Fallot-long term problems and Pre procedural considerations management solutions Maully Shah, MBBS Marion McRae, RN How to evaluate the ACHD patient for CRT Achieving optimal practice standards in ACHD Luc Mertens, MD nursing care: present and future challenges Darlene Rebeyka, RN How to manage the ACHD patient with IART Joachim Hebe, MD Which patients should receive an ICD? Paul Khairy, MD

12:00 pm - 1:00 pm (Lunch) 1:00 pm - 2:30 pm (Simultaneous Breakout Sessions) Session I: How To Session Session II: How to Session How to Improve Patient Safety Psychosocial Challenges of the Medical Team Moderator: Craig Broberg, MD Moderator: Jeanine Harrison, RN Transition: the pediatric priorities in action Delivering difficult news Geraldine Cullen-Dean, RN Adrienne Kovacs, PhD C Psych

Transition: the adult priorities Addressing non-compliance Amy Verstappen, President/CEO ACHA William Davidson, MD Communication of clinical plan Sex, Drugs and Rock & Roll: Reducing the harms Jack Colman, MD associated with risky behavior John Westland, MSW RSW Setting limits within the context of patient-directed care Judith Therrien, MD & Michelle Nickolaus, RN Session III: Meet the Expert Session IV: Meet the Expert Session Evolving Interventions Molecular Approach to CHD: It is all in the Genes Moderator: Gruschen Veldtman, MD Moderator: Seema Mital, MD Setting the scene: current status and future aspects Practical guidelines for referral to genetics in ACHD in ACHD intervention? clinics Felix Berger, MD Chantal Morel, MD

Percutaneous valves in 2008 & beyond 22q11.2 Deletion Syndrome: impact on outcomes in Eric Horlick, MD adulthood Anne Bassett, MD Hybrid procedures – are two heads better than one? Lee Benson, MD / Christopher Caldarone, MD Cardiovascular proteomics: developing new

biomarkers for heart disease The most important intervention I have ever done Maral Ouzounian, MD Contribution from the Audience Personalized medicine: the pharmacogenomic approach to patient care Seema Mital, MD 2:30 pm – 3:00 pm (Break) 3:00 pm – 3:30 pm Original Oral Poster Presentations in ACHD Chairperson: Jolien Roos-Hesselink, MD Abstract Winner #3 Abstract Winner #2

3:30 pm – 5:30 pm The Failing Heart Chairperson: Paul Kantor, MD

• Medical management: How does the ACHD patient differ? Annie Dore, MD

• Is there any role for resynchronization therapy? Seshadri Balaji, MBBS

• Ventricular assist device: bridge to transplant? Vivek Rao, MD

• When should we consider cardiac transplant?

Eduardo Azevedo, MD

• Tissue engineering: Creating a new heart Richard Weisel, MD

5:30 pm Adjourn

Friday June 6th 2008 7:00 am - 8:00 am Continental Breakfast 8:00 am – 5:45 pm Posters on Display (room TBA) 800 am – 10:00 am Pulmonary Hypertension in ACHD Chairperson: Michael Landzberg, MD

• Vascular biology of PAH Duncan Stewart, MD

• PHT: a biventricular disease

Andrew Redington, MD

• Natural or “modified” history of PHT Michael Gatzoulis, MD

• Medical therapies

John Granton, MD

• Surgical therapies Marc De Perrot, MD

10:00 am– 10:30 am (Break) 10:30 am – 12:00 pm (Simultaneous Break Out Sessions) Session I: How To Session Session II: Meet the Expert Session Assessment of RV Function Pulmonary Hypertension in ACHD Moderator: Luc Mertens, MD Moderator: John Granton, MD Pressure-volume loops in congenital heart disease: tool or toy? Should every PHT patient get a vasodilator? Or even Andrew Redington, MD two?

Michael Landzberg, MD Which parameters should be measured by echo in daily practice? Judith Therrien, MD ASD and PHT – to close or not to close? Michael Gatzoulis, MD What do new sophisticated echocardiographic tools add? David Sahn, MD Caregiver burden: Family member experiences Mary McCarthy, RN What can cardiac MRI / CT add? Rachel Wald, MD The transplant window: when to refer and when to list? Cecilia Chaparro, MD Put it all together Luc Mertens, MD Session III: Meet the Expert Session Session IV: Nursing Break Out Session: Research My Toughest Case Moderator: Michelle Nickolaus, RN Moderator: Candice Silversides, MD Developing multi-site research in congenital cardiac Panel: Gary Webb, Carole Warnes, Louise Harris, nursing Seshadri Balaji, Glen Van Arsdell, Gruschen Veldtman, Nancy Pike, RN Paul Kantor (cases will be selected from Philadelphia, Portland and Cardiac Key: evaluating the communication of patient Toronto) information

Fontan >Mustard Jeanine Harrison, RN CcTGA >Ebstein Setting up a PhD Desiree Fleck, RN

12:00 pm – 1:00 pm (Lunch) 1:00 pm – 3:00 pm Timing and Strategies for Interventions Chairperson: David Sahn, MD

• Severe PR in TOF

Gary Webb, MD • Ebstein anomaly

Thomas Spray, MD

• Severe TR and failure of the subaortic RV Andrew Redington, MD

• Congenital coronary anomalies

Christopher Caldarone, MD

• Discrete subaortic stenosis Helmut Baumgartner, MD

3:00 pm – 3:30 pm (Break) 3:30 pm –5:30 pm Challenges of the Fontan Circulation: Any Solution? Chairperson: Christopher Caldarone, MD

• Profile of the Adult Fontan Survivor Nancy Pike ,RN

• Arrhythmias: what to offer from the menu?

Maully Shah, MBBS • The failing Fontan: do we convert too late?

Thomas Spray, MD

• PLE – transplantation the only option? Gruschen Veldtman, MD

• Is 1 ½ ventricle repair better than one ventricle repair?

Glen Van Arsdell, MD 5:30 pm – 5:45 pm Original Oral Poster Presentation in ACHD Chairpersons: Erwin Oechslin, MD & David Sahn, MD Abstract Winner #1 (outstanding) 5:45 pm Adjourn 6:30 pm Bus Departure for Dock – Shuttle from Hotel 7:00 pm Boarding for boat cruise

Saturday June 7th 2008 7:00 am – 7:45 am Continental Breakfast 7:45 am – 9:45 am Challenges in the Care of Adults with CHD Chairperson: Adrienne Kovacs, PhD

• Neurocognitive challenges

Gil Wernovsky, MD

• The dedicated congenital heart surgeon: Does she really make a difference? Tara Karamlou, MD

• Medical and paramedical challenges for the anesthetist Jane Heggie, MD

• Finding the lost ones: strategies to pursue them Amy Verstappen, President/CEO ACHA

9:45 am – 10:15 am (Break)

10:15 am – 11:00 am – Dr. William G. Williams Lecture Chairperson: Glen Van Arsdell, MD

• The long road to better ACHD care Gary Webb, MD

11:00 am – 12:30 pm (Debates) Chairperson: Peter Liu, MD Patients with aortic coarctation need routine screening for intra cranial aneurysm

• Pro: Barbara Mulder, MD • Con: Helmut Baumgartner, MD

The interventionalist is the surgeon’s competitor

• Pro: Thomas Spray, MD • Con: Eric Horlick, MD

PVR must be performed sooner rather than later when percutaneous techniques are available

• Pro: Michael Landzberg, MD • Con: Gary Webb, MD

12: 30 pm Closing Remarks Erwin Oechslin, MD David Sahn, MD Gary Webb, MD

Faculty Members

Course Directors: Erwin Oechslin, MD FRCPC FESC Associate Professor of Medicine University of Toronto Director Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario

Peter Liu, MD PhD Heart & Stroke/Polo Professor Scientific Director, Institute of Circulatory & Respiratory Health Canadian Institute of Health Research Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario

Jeanine Harrison, RN BSc MN APN University of Toronto Faculty of Nursing Advanced Practice Nurse Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Marion McRae, RN MScN ACNP-BC Clinical Associate, Bloomberg Faculty of Nursing University of Toronto Advanced Practice Nurse, Cardiac Surgery Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Course Co-Directors David Sahn, MD FACC Professor of Pediatrics, Diagnostic Radiology, Obstetrics, Gynecology and Biomedical Engineering Oregon Health & Science University Portland, Oregon

Gary Webb, MD FACC Professor of Medicine University of Pennsylvania School of Medicine Director, Philadelphia Adult Congenital Heart Center Philadelphia, PA Desiree Fleck, RN MSN CRNP CCRN Philadelphia Adult Congenital Heart Center The Children’s Hospital of Philadelphia Hospital of the University of Pennsylvania Philadelphia, PA Abstract Co-ordinator: Gil Wernovsky, MD FAAP FACC Professor of Pediatrics University of Pennsylvania School of Medicine Director of Program Development The Children’s Hospital of Philadelphia Philadelphia, PA

Eduardo Azevedo, MD FRCPC FACC Assistant Professor of Medicine University of Toronto Cardiology, Heart Failure, Transplant Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Mount Sinai Hospital Toronto, Ontario Seshadri Balaji, MBBS MRCP(UK) PhD Associate Professor of Pediatrics (Cardiology) Director, Pediatric Arrhythmias, Pacing and Electrophysiology Oregon Health and Science University Portland, Oregon Anne Bassett, MD FRCPC Professor of Psychiatry, University of Toronto Canada Research Chair in Schizophrenia Genetics Director, Clinical Genetics Research Program Centre for Addiction & Mental Health Toronto Congenital Cardiac Centre for Adults Toronto General Hospital Toronto, Ontario Helmut Baumgartner, MD FESC FACC Professor of Adult Congenital Heart Disease University of Muenster Director, Adult Congenital Heart Disease and Valvular Heart Disease Center University Hospital Muenster Muenster, Germany Lee Benson, MD FRCPC FACC FSCAI Professor of Pediatrics (Cardiology) University of Toronto Interventional Cardiology Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Felix Berger, MD Professor of Medicine Director Clinic for Heart Disease and Pediatric CardiologyBerlin, Germany Timothy Bradley, MB ChB FRACP Assistant Professor of Pediatrics University of Toronto Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Craig Broberg, MD FACC Assistant Professor of Medicine Director, Adult Congenital Heart Disease Program Oregon Health and Science University Portland, Oregon Christopher Caldarone, MD FRCSC Associate Professor of Surgery University of Toronto Toronto Congenital Cardiac Centre for Adults The Labatt Family Cardiac Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario

Cecilia Chaparro, MD FRCPC Assistant Professor of Medicine University of Toronto Toronto Lung Transplant Program Cystic Fibrosis Adult Program St. Michael’s Hospital Toronto General Hospital Toronto, Ontario Vijay Chauhan, MD FRCPC Director, Interventional Electrophysiology University of Toronto Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Dr. Jack M. Colman, MD FRCPC FACC Associate Professor of Medicine (Cardiology) University of Toronto Co-Director, Pregnancy & Heart Disease Program Cardiologist Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital and Mount Sinai Hospital Toronto, Ontario Geraldine Cullen-Dean, RN MN Clinical Nurse Specialist Good 2 Go Transition Program Co ordinator Hospital for Sick Children Toronto, Ontario Tirone David, MD FRCSC Professor of Surgery, University of Toronto Division Head, Division of Cardiovascular SurgeryPeter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario William Davidson Jr, MD FACC Professor of Medicine Penn State Heart & Vascular Institute MS Hershey Medical Center Penn State College of Medicine Hershey, PA

Marc de Perrot, MD MSc FRCSC Assistant Professor of Surgery University of Toronto Toronto General Hospital Toronto, Ontario Annie Dore, MD FRCPC Montreal Heart Institute Montreal, Quebec

Michael Gatzoulis, MD PhD FACC FESC Professor of Cardiology Head, Adult Congenital Heart Centre and Centre for Pulmonary Hypertension Royal Brompton Hospital and the National Heart & Lung Institute, Imperial College London, United Kingdom Eric Goldszmidt, MD FRCPC Assistant Professor of Medicine University of Toronto Anesthesiology Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Mount Sinai Hospital Toronto, Ontario

John Granton, MD FRCPC Associate Professor of Medicine University of Toronto Pulmonary Hypertension & Critical Care Medicine Toronto Congenital Cardiac Centre for Adults Toronto General Hospital Toronto, Ontario Robert Hamilton, MD FRCPC Professor of Pediatrics University of Toronto The Labatt Family Heart Centre Hospital for Sick Children Toronto, Ontario Louise Harris, MB ChB FRCP(C) FACC Associate Professor of Medicine University of Toronto Electrophysiologist Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Joachim Hebe, MD Center f. Electrophysiology Am Klinikum Links der Weser Bremen, Germany Jane Heggie, MD FRCPC Assistant Professor of Medicine University of Toronto Cardiac Anesthesia, Cardiovascular Intensive Care, Peri Operative Transesophageal Echocardiography Toronto Congenital Cardiac Centre for Adults Toronto General Hospital Toronto, Ontario

Eric Horlick, MD CM FRCPC Assistant Professor of Medicine University of Toronto Medical Director, Percutaneous Valve Program Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Mark Iwanochko, MD FRCPC FACC Assistant Professor of Medicine University of Toronto Medical Director, Robert J. Burns Nuclear Cardiology Laboratory Peter Munk Cardiac Centre Toronto Western Hospital Toronto, Ontario Paul Kantor, MBB Ch DCH FRCPC Associate Professor of Pediatrics University of Toronto Clinical Head, Heart Failure Service The Labatt Family Heart Centre Hospital for Sick Children Toronto, Ontario Tara Karamlou, MD Department of Surgery Oregon Health & Science University Portland, Oregon Paul Khairy, MD PhD FRCPC Canada Research Chair Electrophysiology & Adult Congenital Heart Disease Montreal Heart Institute Montreal, Quebec

Dr. Adrienne H. Kovacs, PhD C Psych Assistant Professor of Medicine, University of Toronto Clinical Psychologist Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Michael Landzberg, MD Director Boston Adult Congenital Heart and Pulmonary Hypertension Group Brigham and Women’s Hospital Children’s Hospital Boston Harvard University Boston, Mass John MacEachern, BSc Cornwall University President Canadian Congenital Heart Alliance Toronto, Ontario Ariane Marelli, MD FRCPC FACC Associate Professor of Medicine McGill University Director, MAUDE Unit McGill Adult Unit for Congenital Heart Disease Montreal, Quebec Mary McCarthy, RN MA Co-ordinator Pulmonary Hypertension Program Toronto General Hospital Toronto, Ontario

Luc Mertens, MD PhD Associate Professor of Pediatrics University of Toronto Section Head Echocardiography The Labatt Family Heart Centre Hospital for Sick Children Toronto, Ontario Seema Mital, MD FACC Associate Professor of Pediatrics University of Toronto The Labatt Family Heart Centre Hospital for Sick Children Toronto, Ontario Chantal Morel, MD FRCPC FCCMG Assistant Professor of Medicine University of Toronto Clinical and Metabolic Geneticist Fred A. Litwin Family Centre for Genetic Medicine Toronto Congenital Cardiac Centre for Adults Mount Sinai Hospital Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Barbara Mulder, MD PhD FESC Professor of Cardiology Academic Medical Center Amsterdam Amsterdam, The Netherlands Christine Newman, MD FRCPC Assistant Professor of Pediatrics University of Toronto Division of Clinical Pharmacology & ToxicologyThe Max and Beatrice Wolfe Centre for Children’s Grief and Palliative Care Hospital for Sick Children Mount Sinai Hospital Toronto, Ontario

Michelle J. Nickolaus, MSN CRNP Acute Care Nurse Practitioner Instructor of Medicine Program for Adults with Congenital Heart DiseasePenn State Hershey Heart & Vascular Institute Hershey, PA Maral Ouzounian, MD Research Fellow Division of Cardiology Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Narinder Paul, MD FRCPC Assistant Professor of Medicine University of Toronto Chief of Cardiothoracic Imaging Toronto Congenital Cardiac Centre for Adults Toronto General Hospital Toronto, Ontario Joseph Perloff, MD FACC Streisand/American Heart Association Professor Of Medicine and Pediatrics Emeritus Founding Director, Ahmanson/UCLA Adult Congenital Heart Disease Center UCLA School of Medicine Los Angeles, CA Nancy Pike, RN PhD FNP FAHA Nurse Practitioner / Researcher Department of Cardiothoracic Surgery Children’s Hospital of Los Angeles Los Angeles, CA Yves Provost, MD FRCPC Assistant Professor of Medicine University of Toronto Medical Imaging Toronto Congenital Cardiac Centre for Adults Toronto General Hospital Toronto, Ontario Vivek Rao, MD PhD FRCSC FAHA Associate Professor of Surgery University of Toronto Alfred & Teresa DeGasperis Chair in Heart Failure Surgery Surgical Director, Cardiac Transplant and Mechanical Assist Peter Munk Cardiac Centre Toronto General hospital Toronto, Ontario Darlene Rebeyka, RN, MSN, ACNP, CNN(C) Nurse Practitioner, Adult Cardiac Surgery University of Alberta Hospital Edmonton, Alberta Andrew Redington, MD FRCPC Professor of Pediatrics University of Toronto Division Head, Cardiology Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario

Jolien Roos-Hessenlink, MD PhD Cardiologist Congenital Heart Disease Unit Thoraxcenter Erasmus MC Rotterdam, The Netherlands

Matthew Sermer, MD FRCSC Professor of Obstetrics & Gynecology University of Toronto Professor of Medicine, University of Toronto Obstetrics, Gynecology, Maternal-Fetal Medicine Mount Sinai Hospital Toronto, Ontario Maully Shah, MBBS FACC Assistant Professor of Pediatrics University of Pennsylvania School of Medicine Director of International Electrophysiology The Children’s Hospital of Philadelphia Philadelphia, PA Candice Silversides, MD FRCPC Assistant Professor of Medicine University of Toronto Research Director Toronto Congenital Cardiac Centre for Adults Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Samuel Siu, MD SM FRCPC FACC FASE Gunton Professor of Medicine & Chair of Cardiology University of Western Ontario City-Wide Chief of Cardiology London Health Sciences Centre St. Joseph’s Health Care London, Ontario Thomas Spray, MD Professor of Surgery University of Pennsylvania School of Medicine Chief, Division of Cardiothoracic Surgery Alice Langdon Warner Endowed Chair in Pediatric Cardiothoracic Surgery The Children’s Hospital of Philadelphia Philadelphia, PA Duncan Stewart, MD FRCPC CEO and Scientific Director Ottawa Health Research Institute Ottawa, Ontario Judith Therrien, MD Associate Professor of Medicine McGill University MAUDE Unit Jewish General Hospital Montreal, Quebec Glen Van Arsdell, MD FRCSC Professor of Surgery, University of Toronto Head, Cardiovascular Surgery CIT Chair in Cardiovascular Research Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Gruschen Veldtman, MB CHB MRCP Consultant in Pediatric and Adult Congenital Heart Disease Southampton General Hospital Southampton, UK

Amy Verstappen, BA MA Education CEO/President Adult Congenital Heart Association Philadelphia, PA

Rachel Wald, MD FRCPC University of Toronto Pediatric Cardiologist Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Carole Warnes, MD FRCP FACC Professor of Medicine Director, Adult Congenital Heart Disease Mayo Clinic Rochester, MN Richard Weisel, MD FRCSC FACC Professor and Chairman of Surgery University of Toronto Director, Toronto General Research Institute University Health Network Toronto, Ontario John Westland, MSW RSW Social Worker Adolescent Substance Abuse Outreach Program Hospital for Sick Children Toronto, Ontario Bill Williams, MD FRCSC Professor of Surgery University of Toronto Cardiologist Pediatric Congenital Cardiac Centre Toronto Congenital Cardiac Centre for Adults The Labatt Family Heart Centre Hospital for Sick Children Peter Munk Cardiac Centre Toronto General Hospital Toronto, Ontario Linda Wright, MSW MHSc RSW Senior Bioethicist Toronto General Hospital Toronto, Ontario Anji Yetman, MD FACC Professor of Medicine of Pediatrics University of Utah Director, Adult Congenital Cardiac Center Department of Pediatrics & Internal Medicine Divisions of Cardiology Primary Children’s Medical Center Salt Lake City, Utah

Registration Registration Deadline is: May 28th 2008

18th International Symposium on Adult Congenital Heart Disease Congenital Heart Disease in 2008 & Beyond Toronto, Ontario June 4 – 7, 2008 Last Name:_________________________________First Name: _________________________ Title/Degree: __________________________________________________________________ Hospital/Institute: ______________________________________________________________ Specialty: _____________________________________________________________________ Address: ______________________________________________________________________ City: __________________ Province/State: _________________ Postal Code: ______________ Phone: ________________ Fax: ________________ E-mail: _____________________________________

Faculty Dinner (Faculty Members Only) – Thursday June 5th 2008

Registration Fees Full Course (Wed-Sat) Until After April 30 April 30

Physicians…………………………………………………………………$700.00 $800.00 Fellows, Residents, Nurses and other Health Care Professionals……..$500.00 $600.00

Empress Boat Cruise & Dinner – Friday June 6th

# ____ of people @ $48.00/person………………………………………..$_________ Total ……………………………………………………………………………….$_________ Method of Payment

VISA Mastercard American Express

Name on Credit Card: _______________________________________ Credit Card# ______________________________________________ Exp. Date ____/____ Signature _________________________________________________ To register online with a credit card, go to www.uhn.ca/ACHDConference2008.asp If paying by cheque please make your cheque payable to: Please mail the completed registration form and payment to: ACHD International Conference Fund Dr. Erwin Oechslin Toronto General Hospital 585 University Avenue, 5N – 519 Toronto, Ontario, Canada, M5G 2N2 Telephone: 416-340-4871 Fax: 416-340-5014

Sponsorships

We recognize the Generous Support from:

Actelion Pharmaceuticals Canada Inc

AGA Medical Corporate

GE Healthcare

Kardia Health Systems

Endorsements

" Scientific Program endorsed by"

Canadian Adult Congenital Heart Network (CACH Network)

TAsian Pacific Society of Adult Congenital Heart DiseaseT