Topics in Dementia: Papers from the WFN-RGACD 2010...

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Behavioural Neurology 25 (2012) 1–2 1 DOI 10.3233/BEN-2012-0343 IOS Press Introduction Topics in Dementia: Papers from the WFN-RGACD 2010 Meeting Facundo Manes Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina Laboratory of Cognitive Neuroscience, Universidad Diego Portales, Santiago, Chile Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina E-mail: [email protected] On June 15–18, 2010, the World Federation of Neu- rology’s Research Group on Aphasia and Cognitive Disorders (WFN-RGACD) held its biannual meeting in Istanbul, Turkey. Research presented during the meet- ing covered a wide array of topics in the eld of behav- ioral neurology and represented a clear reection of cre- ativity and innovative research aimed at deepening our understanding of some of the most fundamental aspects of this eld. A large portion of the ongoing investiga- tions presented during the meeting focused on different types of dementia. This special issue of Behavioural Neurology surveys an interesting range of topics in the eld of dementia. As a whole, the collection of pa- pers included in this special issue represents some of the trends in dementia research which have been most fruitful in generating innovative ndings with direct implications for assessment, diagnosis, and treatment of different patient populations with dementia. Two articles included in this special issue demon- strate the relevance of incorporating some specic tools in the study of dementia. orsev Yener and collab- orators employed auditory delta evoked- and event- related oscillations obtained from EEG data to com- pare patients with Alzheimer disease with healthy con- trols. Their article demonstrates how electrophysio- logical data can be exploited to incorporate objective measures that may compliment behavioral and cogni- tive assessment of patients with dementia. Andreas Hinz applies mathematical modeling centered on graph theory to dissect and further analyze performance on tasks that have been extensively used in dementia: the tower tasks (e.g. Tower of London and Towe of Hanoi). The article provides detail on the mathematical reason- ing behind this application of math to cognitive assess- ment, and offers conclusions as to why graph theory can bring a better understanding neuropsychological performance and could thus help develop new puzzle tests for cognitive assessment. Four articles then explore particular aspects of cogni- tive functioning in different groups of dementia. Faye Corbette and collaborators offer a novel perspective on the semantic impairment of patients with Alzheimer disease. Their article explores the qualitative changes in semantic performance as disease severity progress- es through time. Julie Snowden and her collaborators examine the performance of patients with semantic de- mentia with predominantly right and predominantly left temporal lobe atrophy on famous face, famous name, and general semantic tasks. By doing so, they report ndings that challenge previously conceived semantic models which have been very inuential in the eld. Ezequiel Gleichgerrcht and collaborators have investi- gated the decision making prole of patients with pri- mary progressive aphasia, and compared their perfor- mance to that of patients with behavioral variant fron- totemporal dementia and healthy controls. Their nd- ings in the context of performance in language tasks of- fer insight into the decision making prole of a type of dementia whose behavioral disturbances are yet to be comprehensively characterized. Finally, Laurie Miller and collaborators provide evidence of differences in the cognitive mechanisms underlying facial emotion pro- ISSN 0953-4180/12/$27.50 2012 – IOS Press and the authors. All rights reserved

Transcript of Topics in Dementia: Papers from the WFN-RGACD 2010...

Page 1: Topics in Dementia: Papers from the WFN-RGACD 2010 Meetingdownloads.hindawi.com/journals/bn/2012/901791.pdf · Topics in Dementia: Papers from the WFN-RGACD 2010 Meeting FacundoManes

Behavioural Neurology 25 (2012) 1–2 1DOI 10.3233/BEN-2012-0343IOS Press

Introduction

Topics in Dementia: Papers from theWFN-RGACD 2010 Meeting

Facundo ManesInstitute of Cognitive Neurology (INECO), Buenos Aires, ArgentinaLaboratory of Cognitive Neuroscience, Universidad Diego Portales, Santiago, ChileInstitute of Neurosciences, Favaloro University, Buenos Aires, ArgentinaE-mail: [email protected]

On June 15–18, 2010, the World Federation of Neu-rology’s Research Group on Aphasia and CognitiveDisorders (WFN-RGACD) held its biannualmeeting inIstanbul, Turkey. Research presented during the meet-ing covered a wide array of topics in the field of behav-ioral neurology and represented a clear reflection of cre-ativity and innovative research aimed at deepening ourunderstandingof some of the most fundamental aspectsof this field. A large portion of the ongoing investiga-tions presented during the meeting focused on differenttypes of dementia. This special issue of BehaviouralNeurology surveys an interesting range of topics in thefield of dementia. As a whole, the collection of pa-pers included in this special issue represents some ofthe trends in dementia research which have been mostfruitful in generating innovative findings with directimplications for assessment, diagnosis, and treatmentof different patient populations with dementia.

Two articles included in this special issue demon-strate the relevance of incorporating some specific toolsin the study of dementia. Gorsev Yener and collab-orators employed auditory delta evoked- and event-related oscillations obtained from EEG data to com-pare patients with Alzheimer disease with healthy con-trols. Their article demonstrates how electrophysio-logical data can be exploited to incorporate objectivemeasures that may compliment behavioral and cogni-tive assessment of patients with dementia. AndreasHinz applies mathematical modeling centered on graphtheory to dissect and further analyze performance ontasks that have been extensively used in dementia: the

tower tasks (e.g. Tower of London and Towe of Hanoi).The article provides detail on the mathematical reason-ing behind this application of math to cognitive assess-ment, and offers conclusions as to why graph theorycan bring a better understanding neuropsychologicalperformance and could thus help develop new puzzletests for cognitive assessment.

Four articles then explore particular aspects of cogni-tive functioning in different groups of dementia. FayeCorbette and collaborators offer a novel perspective onthe semantic impairment of patients with Alzheimerdisease. Their article explores the qualitative changesin semantic performance as disease severity progress-es through time. Julie Snowden and her collaboratorsexamine the performance of patients with semantic de-mentiawith predominantly right and predominantly lefttemporal lobe atrophy on famous face, famous name,and general semantic tasks. By doing so, they reportfindings that challenge previously conceived semanticmodels which have been very influential in the field.Ezequiel Gleichgerrcht and collaborators have investi-gated the decision making profile of patients with pri-mary progressive aphasia, and compared their perfor-mance to that of patients with behavioral variant fron-totemporal dementia and healthy controls. Their find-ings in the context of performance in language tasks of-fer insight into the decision making profile of a type ofdementia whose behavioral disturbances are yet to becomprehensively characterized. Finally, Laurie Millerand collaborators provide evidence of differences in thecognitive mechanisms underlying facial emotion pro-

ISSN 0953-4180/12/$27.50 2012 – IOS Press and the authors. All rights reserved

Page 2: Topics in Dementia: Papers from the WFN-RGACD 2010 Meetingdownloads.hindawi.com/journals/bn/2012/901791.pdf · Topics in Dementia: Papers from the WFN-RGACD 2010 Meeting FacundoManes

2 F. Manes / Introduction

cessing impairment in different populations of patientswith dementia, including behavioral variant frontotem-poral dementia, semantic dementia, and Alzheimer dis-ease. Their assessment through three different facialemotion processing tasks furthers our understandingabout the multifactorial impairment of facial emotion

processing within each pathological group.The quality of research presented in this special issue

represents merely a portion of the creative and stimu-lating intellectual exchange of researchers from aroundthe world who participated in the 2010 meeting of theWFN-RGACD.

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