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Top 200 Section 2

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NT chemical messengers Examples: dopamine norepinephrine GABA serotonin melatonin

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Symptoms of clinical depression change in sleep habits loss of interest irritability, tension, sadness lack of energy http://www.depression.com/depression_animation.html ?content=understanding& http://www.depression.com/depression_animation.html ?content=understanding& Associated conditions anxiety, panic attacks bipolar disorder OCD

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Brand NameGeneric Name Celexa*citalopram Lexaproescitalopram Paxil*paroxetine Prozac*fluoxetine Zoloft*sertraline *available as generics

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Time to take effect Common side effects nausea insomnia loss of appetite sexual dysfunction Serotonin Syndrome

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Brand NameGeneric Name Cymbaltaduloxetine Effexor*venlafaxine Effexor XRvenlafaxine, extended release Pristiqdesvenlafaxine *venlafaxine tablets are available in both regular release & extended release

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Time to take effect Side effect profile similar to SSRIs Serotonin Syndrome

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Brand NameGeneric Name Elavilamitriptyline Pamelornortriptyline Tofranilimipramine

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Common Side Effects Drowsiness/Dizziness Dry mouth Constipation Sexual dysfunction

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Brand NameGeneric Name Buspar*buspirone Desyrel*trazodone Remeron *mirtazapine Stratteraatomoxetine Wellbutrin*, bupropion Wellbutrin XL*,bupropion, ext release (qd) Wellbutrin SR*bupropion, sust. release (bid)

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buspirone augments serotonin levels trazodone sleep atomoxetine norepinephrine reuptake inhibitor bupropion No sexual side effects Lowers seizure threshold Various forms available (regular release tabs, extended release tabs, sustained release tabs)

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Black Box Warning Abrupt Discontinuation Syndrome Interaction with MAOIs

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Brand NameGeneric Name Ativanlorazepam Klonopinclonazepam Restoriltemazepam Valiumdiazepam Xanaxalprazolam

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Drowsiness Impair judgement Respiratory depression Increased risk of falls in the elderly Controlled substances = highly addictive

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Brand NameGeneric Name Ambien, Ambien Crzolpidem Lunestaeszopiclone