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Rank Brand name (Generic name)* Most common use(s) Therapeutical Class  

1 Lipitor (Atorvastatin) High cholesterol treatment HMG-CoA reductase inhibitor

2Lorcet, Lortab, Norco,Vicodin (Hydrocodone and Acetaminophen) Pain treatment Narcotic analgesic

3 Toprol-XL (Metoprolol-XL)

High blood pressure, heart failure, or chest

pain treatment Beta-blocker

4 Norvasc (Amlodipine) High blood pressure treatment Calcium channel blocker (CCB)

5 Amoxil, Trimox (Amoxicillin) Bacterial infection treatment Penicillin

6

Lorcet, Lortab, Norco,

Vicodin (Hydrocodone and Acetaminophen) Pain treatment Narcotic analgesic

7 Synthroid (Levothyroxine Sodium) Thyroid hormone deficiency treatment Thyroid hormone replacement

8 Nexium (Esomeprazole) Ulcers or reflux (GERD) treatment Proton pump inhibitor

9 Lexapro (Escitalopram) Depression or anxiety treatment Selective serotonin reuptake inhibitor

10 Proventil (Albuterol) Asthma treatment Beta2-agonist

11 Singulair (Montelukast) Asthma and/or allergies treatment/ prevention Leukotriene receptor antagonist

12 Synthroid, Levoxyl (Levothyroxine Sodium) Thyroid hormone deficiency treatment Thyroid hormone replacement

13 Prinivil, Zestril (Lisinopril) High blood pressure or heart failure treatment ACE-Inhibitor (ACE-I)

14 Ambien (Zolpidem) Insomnia treatment Hypnotic15 Zyrtec (Cetirizine) Allergy treatment/ prevention Antihistamine

16 Prevacid (Lansoprazole) Ulcers or reflux (GERD) treatment Proton pump inhibitor

17 Zoloft (Sertraline) Depression or anxiety treatment Selective serotonin reuptake inhibitor

18 Coumadin (Warfarin Sodium) Blood clot prevention Anticoagulant

19 Advair Diskus (Fluticasone and Salmeterol) Asthma treatment/prevention

Combination oral corticosteroid and

long-acting beta2-agonist

20 Lasix (Furosemide) Edema or hypertension treatment Loop diuretic

21 Fosamax (Alendronate) Osteoporosis treatment and prevention Bisphosphonate

22 Protonix (Pantoprazole) Ulcers or reflux (GERD) treatment Proton pump inhibitor23 Zithromax (Azithromycin) Bacterial infection treatment Macrolide

24 Effexor XR (Venlafaxine) Depression or anxiety treatment

Serotonin/Norephinephrine reuptake

inhibitor

25 Zocor (Simvastatin) High cholesterol treatment HMG-CoA reductase inhibitor

26 Plavix (Clopidogrel) Blood clot prevention Antiplatelet agent

27 Synthroid, Levoxyl (Levothyroxine Sodium) Thyroid hormone deficiency treatment Thyroid hormone replacement

28

Percocet, Tylox,

Roxicet, Endocet (Oxycodone and Acetaminophen) Pain treatment Narcotic analgesic

Top 200 drugs by prescription count, 2006 (Sorted by RANK)

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29 Vytorin (Simvastatin and ezetimibe) High cholesterol treatment

Combination HMG-CoA reductase

inhibitor and 2-azetidinone

30 Keflex (Cephalexin) Bacterial infection treatment Cephalosporin (1st generation)

31 Diovan (Valsartan) High blood pressure or heart failure treatment Angiotensin receptor blocker (ARB)

32 Prinivil, Zestril (Lisinopril) High blood pressure or heart failure treatment ACE-Inhibitor (ACE-I)

33 Glucophage (Metformin HCl) Glycemic control improvement Biguanide

34 Tenormin (Atenolol) High blood pressure or chest pain treatment Beta-blocker

35 Prednisone (Prednisone)

Treat variety of diseases including, but not

limited to: acute allergy, inflammation,

asthma, organ transplantation. Oral corticosteroid36 Levaquin (Levofloxacin) Bacterial infection treatment Quinolone

37 Lotrel (Benazepril and Amlodipine) High blood pressure treatment Combination ACE-I and CCB

38 Tenormin (Atenolol) High blood pressure or chest pain treatment Beta-blocker

39 Lopressor (Metoprolol Tart) High blood pressure treatment Beta-blocker

40 Zetia (Ezetimibe) High cholesterol treatment 2-Azetidinone

41 Seroquel (Quetiapine) Schizophrenia treatment Antipsychotic (Atypical)

42 Wellbutrin XL (Bupropion) Depression treatment Dopamine-reuptake inhibitor

43 Celebrex (Celecoxib) Pain treatment COX-2 inhibitor44 Avandia (Rosiglitazone) Glycemic control improvement Thiazolidinedione

45 Microzide (Hydrochlorothiazide) High blood pressure treatment Diuretic

46 Actos (Pioglitazone) Glycemic control improvement Thiazolidinedione

47 Diovan HCT (Valsartan and Hydrochlorothiazide) High blood pressure treatment Combination ARB and diuretic

48 Premarin (Conjugated estrogens) Menopausal symptom treatment Estrogen derivative

49 Altace (Ramipril) High blood pressure or heart failure treatment ACE-Inhibitor (ACE-I)

50 Crestor (Rosuvastatin) High cholesterol treatment HMG-CoA reductase inhibitor

51 Zithromax (Azithromycin) Bacterial infection treatment Macrolide

52 Coreg (Carvedilol) High blood pressure or heart failure treatment Beta-blocker

53 Flomax (Tamsulosin) Prostate / urinary disorder treatment Alpha1-blocker

54 Actonel (Risedronate) Osteoporosis treatment and prevention Bisphosphonate

55 Levoxyl (Levothyroxine Sodium) Thyroid hormone deficiency treatment Thyroid hormone replacement

56 Nasonex (Mometasone) Allergy treatment/ prevention Corticosteroid

57 Microzide (Hydrochlorothiazide) High blood pressure treatment Thiazide diuretic

58 Risperdal (Risperidone) Schizophrenia treatment Antipsychotic (Atypical)59 Yasmin (Drospirenone and Ethinyl Estradiol) Pregnancy prevention Oral contraceptive

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60 Lantus (Insulin Glargine) Glycemic control improvement Insulin

61 Amoxil, Trimox (Amoxicillin) Bacterial infection treatment Penicillin

62 Viagra (Sildenafil) Erectile dysfunction treatment Phosphodiesterase-5 inhibitor

63 Tricor (Fenofibrate) High cholesterol treatment Cholesterol lowering agent

64 Xanax (Alprazolam) Anxiety treatment Benzodiazepine65 Xanax (Alprazolam) Anxiety treatment Benzodiazepine

66 Cozaar (Losartan) High blood pressure or heart failure treatment Angiotensin receptor blocker (ARB)

67 Digitek (Digoxin) Heart failure or irregular heartbeat treatment Cardiac glycoside

68 Xanax (Alprazolam) Anxiety treatment Benzodiazepine

69 Lasix (Furosemide) Edema or hypertension treatment Loop diuretic

70 Motrin (Ibuprofen Rx) Pain treatment NSAID71 Desyrel (Trazodone HCl) Depression treatment Serotonin reuptake inhibitor

72 Cymbalta (Duloxetine)

Depression or diabetic neuropathic pain

treatment

Serotonin/Norephinephrine reuptake

inhibitor

73 Tylenol with Codeine (Acetaminophen and Codeine) Pain treatment Narcotic analgesic

74 Dyazide, Maxzide (Triamterene and Hydrochlorothiazide) High blood pressure treatment

Combination thiazide and potassium-

sparing diuretic

75 Paxil (Paroxetine HCl) Depression or anxiety treatment Selective serotonin receptor inhibitor

76 Microzide (Hydrochlorothiazide) High blood pressure treatment Thiazide diuretic

77 Adderall XR (Amphetamine and Dextroamphetamine)Attention deficit hyperactivity disorder(ADHD) control Stimulant

78 Klonopin (Clonazepam) Anxiety treatment Benzodiazepine

79 Omnicef (Cefdinir) Bacterial infection treatment Cephalosporin (3rd generation)

80 Aricept (Donepezil) Alzheimers-type dementia treatment Acetylcholinesterase inhibitor

81 Prozac (Fluoxetine HCl) Depression or anxiety treatment Selective serotonin receptor inhibitor

82 Darvocet (Propoxyphene and Acetaminophen) Pain treatment Narcotic analgesic

83 Neurotin (Gabapentin) Seizure control Anticonvulsant

84 Allegra (Fexofenadine HCl) Allergy treatment/ prevention Antihistamine

85 Zocor (Simvastatin) High cholesterol treatment HMG-CoA reductase inhibitor

86 Valtrex (Valaciclovir) Viral infection treatment Antiviral

87 Motrin (Ibuprofen Rx) Pain treatment NSAID

88 Lasix (Furosemide) Edema or hypertension treatment Loop diuretic

89 Amoxil, Trimox (Amoxicillin) Bacterial infection treatment Penicillin

90

Lorcet, Lortab, Norco,

Vicodin (Hydrocodone and Acetaminophen) Pain treatment Narcotic analgesic

91 Concerta (Methylphenidate)

Attention deficit hyperactivity disorder

(ADHD) control Stimulant92 Ortho-Tri-Cyclen Lo (Norgestimate and Ethinyl Estradiol) Pregnancy prevention Oral contraceptive

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193 Nasacort AQ (Triamcinolone) Allergy treatment/ prevention Nasal corticosteroid

194 Neurotin (Gabapentin)

Seizures control, postherpetic neuralgia

management Anticonvulsant

195 Tenormin (Atenolol) High blood pressure or chest pain treatment Beta-blocker196 Imdur (Isosorbide Mononitrate) Chest pain prevention Vasodilator

197 Lopressor (Metoprolol Tart) High blood pressure treatment Beta-blocker

198 Phenergan (Promethazine) Nausea control Antiemetic

199 Paxil (Paroxetine HCl) Depression or anxiety treatment Selective serotonin receptor inhibitor

200 Ultram (Tramadol) Pain treatment Non-narcotic analgesic

* Note: Products offered by multiple manufacturers may appear on the list more than once.

http://pharmacytimes.com/Article.cfm?Menu=1&ID=4629

Acknowledgement: Prepared by Justin Lusk and Brandon Williams 

SOURCE: Pharmacy Times , Top 200 Prescription Drugs of 2006