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Publication Title Authors GrantNumber(s)

Journal (Pub date) PubMedLink

PubYear

Blood DNA methylation biomarkers of cumulativelead exposure in adults.

Colicino, Elena; Just,Allan;Kioumourtzoglou,Marianthi-Anna;Vokonas, Pantel;Cardenas, Andre ...

P30ES000002,P30ES009089,P30ES023515,R01ES025225,R01ES027747,R01ES028805

J Expo Sci EnvironEpidemiol (2021 Feb)

31636367

2021

Genetically Increased Telomere Length andAging-Related Traits in the U.K. Biobank.

Demanelis, Kathryn;Tong, Lin; Pierce,Brandon L

R35ES028379 J Gerontol A Biol Sci MedSci (2021 Jan 01)

31603979

2021

Gestational perfluoroalkyl substance exposure andbody mass index trajectories over the first 12 yea ...

Braun, Joseph M; Eliot,Melissa; Papandonatos,George D; Buckley,Jessie P; Cecil, Kim M;Kalkw ...

R01ES025214,R01ES027224,R01ES030078,R01ES030078,R01ES030078,R01ES030078

Int J Obes (Lond) (2021Jan)

33208860

2021

Investigation of Break-Induced Replication in Yeast. Osia, Beth; Elango,Rajula; Kramara, Juraj;Roberts, Steven A;Malkova, Anna

R21ES030307 Methods Mol Biol (2021) 32840789

2021

Noninvasive Assessment of Epidermal GenomicMarkers of UV Exposure in Skin.

Muradova, Elnara;Patel, Nishit; Sell,Brittney; Bittencourt,Bruna B; Ojeda, SandraS; Adelman ...

R01ES030562 J Invest Dermatol (2021Jan)

32553564

2021

PCB126 Exposure Revealed Alterations in m6A RNAModifications in Transcripts Associated With AHRAct ...

Aluru, Neelakanteswar;Karchner, Sibel I

P01ES028938,R01ES024915,R01ES024915

Toxicol Sci (2021 Jan 06) 33064826

2021

Per- and polyfluoroalkyl substance mixtures andgestational weight gain among mothers in the Health ...

Romano, Megan E;Gallagher, Lisa G;Eliot, Melissa N;Calafat, Antonia M;Chen, Aimin; Yolton, ...

P30ES013508,R01ES025214

Int J Hyg Environ Health(2021 Jan)

33181449

2021

Production and Analysis of Human Primordial GermCell-Like Cells.

Mitsunaga, Shino;Shioda, Keiko; Hanna,Jacob H; Isselbacher,Kurt J; Shioda, Toshi

R01ES023316,R01ES023316

Methods Mol Biol (2021) 32852762

2021

Transcriptomic and Epigenetic Preservation of GeneticSex Identity in Estrogen-feminized Male Chicke ...

Shioda, Keiko;Odajima, Junko;Kobayashi, Misato;Kobayashi, Mutsumi;Cordazzo, Bianca;Isselba ...

R01ES020454,R01ES020454,R01ES023316,R01ES023316

Endocrinology (2021 Jan01)

33170207

2021

A map of cis-regulatory elements and 3D genomestructures in zebrafish.

Yang, Hongbo; Luan,Yu; Liu, Tingting; Lee,Hyung Joo; Fang, Li;Wang, Yanli; Wang,Xiaotao; ...

U24ES026699 Nature (2020 Dec) 33239788

2020

A naturally-occurring 22-bp coding deletion inUgt86Dd reduces nicotine resistance in Drosophilamel ...

Macdonald, Stuart J;Highfill, Chad A

R01ES029922 BMC Res Notes (2020 Mar30)

32228671

2020

A Positive Feedback Loop Between c-MycUpregulation, Glycolytic Shift, and HistoneAcetylation Enhan ...

Clementino, Marco;Xie, Jie; Yang, Ping; Li,Yunfei; Lin, Hsuan-Pei;Fenske, William K;Tao, ...

R01ES026151,R01ES029942

Toxicol Sci (2020 09 01) 32525551

2020

A precision medicine approach to defining the impactof doxorubicin on the bioenergetic-metabolite i ...

Smith, Matthew Ryan;Chacko, Balu K;Johnson, Michelle S;Benavides, Gloria A;Uppal, Karan; Go ...

P30ES019776,R01ES023485,U2CES026560

Redox Biol (2020 01) 31546171

2020

A Robust Method Uncovers SignificantContext-Specific Heritability in Diverse ComplexTraits.

Dahl, Andy; Nguyen,Khiem; Cai, Na;Gandal, Michael J;Flint, Jonathan; Zaitlen,Noah

R01ES029929 Am J Hum Genet (2020 0102)

31901249

2020

A special issue dedicated to Dr. Bruce N. Ames:Introduction.

Walker, Graham C R35ES028303 Mutat Res (2020 01) 32087846

2020

A stapled POL κ peptide targets REV1 to inhibitmutagenic translesion synthesis.

Chatterjee, Nimrat;D'Souza, Sanjay;Shabab, Mohammad;Harris, Cynthia A;Hilinski, Gerard J; V ...

P30ES002109,R35ES028303

Environ Mol Mutagen(2020 10)

32573829

2020

A vision for exposome epidemiology: The pregnancyexposome in relation to breast cancer in the Child ...

Jones, Dean P; Cohn,Barbara A

P30ES019776,R01ES023485,U2CES026560,U2CES030163

Reprod Toxicol (2020 03) 32197999

2020

Accelerated epigenetic aging as a risk factor forchronic obstructive pulmonary disease and decrease ...

Breen, Miyuki;Nwanaji-Enwerem,Jamaji C; Karrasch,Stefan; Flexeder,Claudia; Schulz,Holger; ...

R01ES025225,R01ES027747

Aging (Albany NY) (202008 03)

32747609

2020

Activation of β-Catenin Signaling and its CrosstalkWith Estrogen and Histone Deacetylases in Human ...

Ali, Mohamed; Shahin,Sara Mahmoud; Sabri,Nagwa Ali; Al-Hendy,Ayman; Yang, Qiwei

R01ES028615 J Clin Endocrinol Metab(2020 04 01)

31761932

2020

Activity profiling and crystal structures ofinhibitor-bound SARS-CoV-2 papain-like protease: Afram ...

Rut, Wioletta; Lv,Zongyang; Zmudzinski,Mikolaj; Patchett,Stephanie; Nayak,Digant; Snipas, ...

R01ES025166 Sci Adv (2020 10) 33067239

2020

Adipose tissue-liver crosstalk during pathologicchanges caused by vinyl chloride metabolites in mic ...

Kaelin, Brenna R;McKenzie, Collin M;Hempel, Karl W; Lang,Anna L; Arteel, GavinE; Beier, Ju ...

R21ES031531 Toxicol Appl Pharmacol(2020 07 15)

32445754

2020

Agrochemicals and obesity. Ren, Xiao-Min; Kuo,Yun; Blumberg, Bruce

R01ES023316,R01ES023316

Mol Cell Endocrinol (202009 15)

32619583

2020

Alcohol Consumption and Risk of Uterine Fibroids. Takala, Hajra; Yang,Qiwei; El Razek,Ahmed M Abd; Ali,Mohamed; Al-Hendy,Ayman

R01ES028615 Curr Mol Med (2020) 31612831

2020

An Evolutionary Insertion in the Mxra8Receptor-Binding Site Confers Resistance toAlphavirus Infect ...

Kim, Arthur S;Zimmerman, Ofer; Fox,Julie M; Nelson,Christopher A; Basore,Katherine; Zhang, ...

U24ES026699 Cell Host Microbe (202003 11)

32075743

2020

An introduction for the special issue on environmentalhealth and genome integrity.

Yan, Shan; Vaziri,Cyrus

R01ES029079 Environ Mol Mutagen(2020 08)

32683747

2020

Analysis of Telomere Length and Aberrations byQuantitative FISH.

Fouquerel, Elise;Opresko, Patricia


2020

AP-endonuclease 1 sculpts DNA through an anchoringtyrosine residue on the DNA intercalating loop.

Hoitsma, Nicole M;Whitaker, Amy M;Beckwitt, Emily C;Jang, Sunbok; Agarwal,Pratul K; Van Hou ...

R01ES029203 Nucleic Acids Res (202007 27)

32542366

2020

Arsenic and benzo[a]pyrene co-exposure actssynergistically in inducing cancer stem cell-like proper...

Wang, Zhishan; Yang,Ping; Xie, Jie; Lin,Hsuan-Pei; Kumagai,Kazuyoshi; Harkema,Jack; Yang, ...

P30ES026529,R01ES028256

Environ Int (2020 04) 32062438

2020

Arsenic Exposure and Compromised Protein QualityControl.

Tam, Lok Ming; Wang,Yinsheng

R35ES031707 Chem Res Toxicol (2020Jul 20)

32410444

2020

Arsenic-induced changes in miRNA expression incancer and other diseases.

Ferragut Cardoso, AnaP; Udoh, Karen T;States, J Christopher

P30ES030283,R01ES027778

Toxicol Appl Pharmacol(2020 12 15)

33127375

2020

Arsenite Binds to ZNF598 to PerturbRibosome-Associated Protein Quality Control.

Tam, Lok Ming; Jiang,Ji; Wang, Pengcheng;Wang, Yinsheng

R35ES031707 Chem Res Toxicol (2020Jul 20)

32324387

2020

Arsenite Exposure Displaces Zinc from ZRANB2Leading to Altered Splicing.

Banerjee, Mayukh;Ferragut Cardoso, AnaP; Lykoudi, Angeliki;Wilkey, Daniel W; Pan,Jianmin; W ...

R01ES027778 Chem Res Toxicol (2020Jun 15)

32274925

2020

Asbestos induces mesothelial cell transformation viaHMGB1-driven autophagy.

Xue, Jiaming;Patergnani, Simone;Giorgi, Carlotta;Suarez, Joelle; Goto,Keisuke; Bononi, Ang...

R01ES030948 Proc Natl Acad Sci U S A(2020 10 13)

32999071

2020

Assessing the impact of arsenic metabolism efficiencyon DNA methylation using Mendelian randomizati ...

DiGiovanni, Anthony;Demanelis, Kathryn;Tong, Lin; Argos,Maria; Shinkle, Justin;Jasmine, Fa ...

R35ES028379 Environ Epidemiol (2020Apr)

32337471

2020

Association of Neutrophil to Lymphocyte Ratio WithPulmonary Function in a 30-Year Longitudinal Stud ...

Gao, Xu; Coull, Brent;Lin, Xihong; Vokonas,Pantel; Sparrow, David;Hou, Lifang; DeMeo,Dawn ...

P30ES009089,R01ES025225,R01ES027747

JAMA Netw Open (202007 01)

32658288

2020

Associations between attention deficit hyperactivitydisorder symptoms and eating behaviors in early ...

Fuemmeler, Bernard F;Sheng, Yaou;Schechter, Julia C; Do,Elizabeth; Zucker,Nancy; Majors, A ...

R24ES028531 Pediatr Obes (2020 07) 32119190

2020

Associations between maternal obesity, gestationalcytokine levels and child obesity in the NEST coh ...

Maguire, Rachel L;House, John S; Lloyd,Dillon T; Skinner,Harlyn G; Allen,Terrence K; Raffi, ...

P30ES025128,R24ES028531

Pediatr Obes (2020 Dec30)

33381912

2020

Associations of annual ambient PM2.5 componentswith DNAm PhenoAge acceleration in elderly men:The ...

Wang, Cuicui;Koutrakis, Petros; Gao,Xu; Baccarelli, Andrea;Schwartz, Joel

P30ES009089,R01ES025225,R01ES027747

Environ Pollut (2020 Mar) 31818625

2020

Associations of smoking and air pollution withperipheral blood RNA N6-methyladenosine in theBeijin ...

Kupsco, Allison;Gonzalez, Gwendolyn;Baker, Brennan H;Knox, Julia M; Zheng,Yinan; Wang, She ...

P30ES009089,R01ES025121,R01ES025225,R01ES027845,T32ES007322

Environ Int (2020 11) 32791345

2020

Asymmetric repair of UV damage in nucleosomesimposes a DNA strand polarity on somatic mutationsin ...

Mao, Peng; Smerdon,Michael J; Roberts,Steven A; Wyrick, JohnJ

R01ES028698 Genome Res (2020 01) 31871068

2020

Atypical UV Photoproducts Induce Non-canonicalMutation Classes Associated with Driver Mutations in...

Laughery, Marian F;Brown, Alexander J;Bohm, Kaitlynne A;Sivapragasam, Smitha;Morris, Haley ...

R01ES028698,R21ES029655

Cell Rep (2020 Nov 17) 33207206

2020

Biomarkers of aging and lung function in thenormative aging study.

Wang, Cuicui; Just,Allan; Heiss, Jonathan;Coull, Brent A; Hou,Lifang; Zheng, Yinan;Sparrow ...

P30ES000002,P30ES009089,R01ES025225,R01ES027747


32561690

2020

Cancer Risks Associated With Germline PALB2Pathogenic Variants: An International Study of 524Famil ...

Yang, Xin; Leslie,Goska; Doroszuk,Alicja; Schneider,Sandra; Allen, Jamie;Decker, Brennan; ...

R01ES027121 J Clin Oncol (2020 03 01) 31841383

2020

Catalytic mechanism of the mismatch-specific DNAglycosylase methyl-CpG-binding domain 4.

Ouzon-Shubeita, Hala;Jung, Hunmin; Lee,Michelle H; Koag,Myong-Chul; Lee,Seongmin

R01ES026676 Biochem J (2020 05 15) 32297632

2020

Cell Types in Environmental Epigenetic Studies:Biological and Epidemiological Frameworks.

Campbell, Kyle A;Colacino, Justin A;Park, Sung Kyun;Bakulski, Kelly M

P30ES017885,P42ES017198,R01ES025531,R01ES025574,R01ES028802,R01ES028802,R01ES028802,R01ES028802,U01ES026697

Curr Environ Health Rep(2020 09)

32794033

2020

Cell-type-specific 3D epigenomes in the developinghuman cortex.

Song, Michael;Pebworth, Mark-Phillip;Yang, Xiaoyu; Abnousi,Armen; Fan, Changxu;Wen, Jia; R ...

U24ES026699 Nature (2020 Nov) 33057195

2020

Cellular diversity of the regenerating caudal fin. Hou, Yiran; Lee, HyungJoo; Chen, Yujie; Ge,Jiaxin; Osman, FujrOsman Ibrahim;McAdow, Anthon ...

U24ES026699 Sci Adv (2020 Aug) 32851162

2020

Certain ortho-hydroxylated brominated ethers arepromiscuous kinase inhibitors that impair neuronal ...

Poston, Robert G;Murphy, Lillian;Rejepova, Ayna;Ghaninejad-Esfahani,Mina; Segales, Joshua;...

R01ES028738 J Biol Chem (2020 05 01) 32229587

2020

Characterization of long G4-rich enhancer-associatedgenomic regions engaging in a novel loop:loop ' ...

Williams, Jonathan D;Houserova, Dominika;Johnson, Bradley R;Dyniewski, Brad;Berroyer, Alexa ...

R01ES030084,R01ES030084

Nucleic Acids Res (202006 19)

32383760

2020

Chemical mixtures and neurobehavior: a review ofepidemiologic findings and future directions.

Vuong, Ann M; Yolton,Kimberly; Braun,Joseph M; Lanphear,Bruce P; Chen, Aimin

P30ES013508,R01ES025214

Rev Environ Health (2020Sep 25)

32598325

2020

Chromatin remodeling and mismatch repair: Accessand excision.

Goellner, Eva M R00ES026653 DNA Repair (Amst) (202001)

31698199

2020

Chromosomal alterations among age-relatedhaematopoietic clones in Japan.

Terao, Chikashi;Suzuki, Akari;Momozawa, Yukihide;Akiyama, Masato;Ishigaki, Kazuyoshi;Yamam ...

DP2ES030554 Nature (2020 08) 32581364

2020

Chronic and acute arsenic exposure enhance EGFRexpression via distinct molecular mechanisms.

Kim, Christine; States,J Christopher; Ceresa,Brian P

R01ES027778,T32ES011564

Toxicol In Vitro (2020Sep)

32599262

2020

Chronic exposure to cadmium induces a malignanttransformation of benign prostate epithelial cells.

Chandrasekaran, Balaji;Dahiya, Nisha R; Tyagi,Ashish; Kolluru,Venkatesh; Saran,Uttara; Baby ...

R01ES027778,R01ES028102,R01ES030019

Oncogenesis (2020 Feb 17) 32066655

2020

Co-opted transposons help perpetuate conservedhigher-order chromosomal structures.

Choudhary, MayankNk; Friedman, Ryan Z;Wang, Julia T; Jang,Hyo Sik; Zhuo, Xiaoyu;Wang, Ting

U24ES026699 Genome Biol (2020 01 24) 31973766

2020

CofActor: A light- and stress-gated optogeneticclustering tool to study disease-associated cytoskel ...

Salem, Fatema B;Bunner, Wyatt P;Prabhu, Vishwanath V;Kuyateh, Abu-Bakarr;O'Bryant, Collin T ...

R15ES029673,R15ES029673,R15ES029673,R15ES029673

J Biol Chem (2020 08 07) 32424038

2020

Collision-Induced Dissociation Studies of ProtonatedIons of Alkylated Thymidine and 2'-Deoxyguanosi ...

Cui, Yuxiang; Yuan,Jun; Wang, Pengcheng;Wu, Jun; Yu, Yang;Wang, Yinsheng

R01ES029749 J Am Soc Mass Spectrom(2020 Apr 01)

32134268

2020

Comparison of differential accessibility analysisstrategies for ATAC-seq data.

Gontarz, Paul; Fu,Shuhua; Xing,Xiaoyun; Liu,Shaopeng; Miao,Benpeng; Bazylianska,Viktoriia ...

U24ES026699 Sci Rep (2020 06 23) 32576878

2020

Comparison of the Base Excision and Direct ReversalRepair Pathways for Correcting 1,N6-Ethenoadenin ...

Caffrey, Paul J; Kher,Raadhika; Bian, Ke; Li,Deyu; Delaney, Sarah

R01ES028865,R01ES028865

Chem Res Toxicol (2020Jul 20)

32293880

2020

Comprehensive Molecular Characterization IdentifiesDistinct Genomic and Immune Hallmarks of Renal M...

Msaouel, Pavlos;Malouf, Gabriel G; Su,Xiaoping; Yao, Hui;Tripathi, Durga N;Soeung, Melinda ...

R01ES029680 Cancer Cell (2020 05 11) 32359397

2020

Comprehensive structure-function characterization ofDNMT3B and DNMT3A reveals distinctive de novoD ...

Gao, Linfeng; Emperle,Max; Guo, Yiran;Grimm, Sara A; Ren,Wendan; Adam,Sabrina; Uryu, Hide ...

R35ES031707 Nat Commun (2020 07 03) 32620778

2020

Concentration-response evaluation of ToxCastcompounds for multivariate activity patterns of neural...

Kosnik, Marissa B;Strickland, Jenna D;Marvel, Skylar W;Wallis, Dylan J;Wallace, Kathleen; R ...

P30ES025128,R56ES030007

Arch Toxicol (2020 02) 31822930

2020

Concentrations and loadings of organophosphate andreplacement brominated flame retardants in house ...

Percy, Zana; LaGuardia, Mark J; Xu,Yingying; Hale, RobertC; Dietrich, Kim N;Lanphear, Bruc ...

P30ES006096,R01ES025214,R01ES027224

Chemosphere (2020 Jan) 31499316

2020

Content and Performance of the MiniMUGAGenotyping Array: A New Tool To Improve Rigor andReproducib ...

Sigmon, JohnSebastian; Blanchard,Matthew W; Baric,Ralph S; Bell, TimothyA; Brennan, Jennife ...

P42ES031007,R01ES029925

Genetics (2020 Dec) 33067325

2020

Copper associates with differential methylation inplacentae from two US birth cohorts.

Kennedy, Elizabeth;Everson, Todd M;Punshon, Tracy;Jackson, Brian P; Hao,Ke; Lambertini, Lu ...

P30ES019776,R01ES025145,R01ES025145,R24ES028507

Epigenetics (2020 03) 31462129

2020

Cross-linking of the DNA repair proteinO6-alkylguanine DNA alkyltransferase to DNA in thepresence ...

Ming, Xun;Michaelson-Richie,Erin D; Groehler 4th,Arnold S; Villalta, PeterW; Campbell, Coli ...

R01ES023350 DNA Repair (Amst) (202005)

32283495

2020

DeepH&M: Estimating single-CpGhydroxymethylation and methylation levels fromenrichment and restric ...

He, Yu; Jang, Hyo Sik;Xing, Xiaoyun; Li,Daofeng; Vasek,Michael J; Dougherty,Joseph D; Wang ...

U24ES026699 Sci Adv (2020 Jul) 32937429

2020

Defective postreplication repair of UV photoproductsin melanoma: a mutator phenotype.

Brash, Douglas E;Seidman, Michael M

R01ES030562 Mol Oncol (2020 01) 31821728

2020

Derivation of stable embryonic stem cell-like, buttranscriptionally heterogenous, induced pluripote ...

Garbutt, Tiffany A;Konganti, Kranti;Konneker, Thomas;Hillhouse, Andrew;Phelps, Drake; Jones ...

U01ES026717 Mamm Genome (2020 12) 33015751

2020

Derivation of trophoblast stem cells from naïve humanpluripotent stem cells.

Dong, Chen; Beltcheva,Mariana; Gontarz, Paul;Zhang, Bo; Popli,Pooja; Fischer, Laura A;Khan ...

U24ES026699 Elife (2020 Feb 12) 32048992

2020

Detection and Discrimination of DNA AdductsDiffering in Size, Regiochemistry, and FunctionalGroup ...

Nookaew, Intawat;Jenjaroenpun, Piroon;Du, Hua; Wang,Pengcheng; Wu, Jun;Wongsurawat, Thidat ...

R01ES029749 Chem Res Toxicol (2020Dec 21)

32799528

2020

Determinants of telomere length across human tissues.

Demanelis, Kathryn;Jasmine, Farzana; Chen,Lin S; Chernoff,Meytal; Tong, Lin;Delgado, Dayan ...

P30ES027792,R35ES028379

Science (2020 09 11) 32913074

2020

Deubiquitinase USP7-mediated MCL-1 up-regulationenhances Arsenic and Benzo(a)pyrene co-exposure-ind...

Yang, Ping; Xie, Jie; Li,Yunfei; Lin, Hsuan-Pei;Fenske, William;Clementino, Marco;Jiang, ...

R01ES028256 Theranostics (2020) 32802178

2020

Development of a DNA Adductome Mass SpectralDatabase.

Guo, Jingshu; Turesky,Robert J; Tarifa,Anamary; DeCaprio,Anthony P; Cooke,Marcus S; Walmsle ...

R01ES019564,R03ES031188

Chem Res Toxicol (202004 20)

32223224

2020

Developmental Exposure to PCB153(2,2',4,4',5,5'-Hexachlorobiphenyl) Alters CircadianRhythms and th ...

Aluru, Neelakanteswar;Krick, Keegan S;McDonald, Adriane M;Karchner, Sibel I

R01ES024915,R01ES024915

Toxicol Sci (2020 01 01) 31621872

2020

Developmental origins of transgenerational spermhistone retention following ancestral exposures.

Ben Maamar, Millissia;Beck, Daniel; Nilsson,Eric; McCarrey, JohnR; Skinner, Michael K

R01ES012974,R01ES012974

Dev Biol (2020 Sep 01) 32628935

2020

Differential contribution of bone marrow-derivedinfiltrating monocytes and resident macrophages to ...

Gangwar, RoopeshSingh; Vinayachandran,Vinesh; Rengasamy,Palanivel; Chan, Ricky;Park, Bongso ...

R01ES019616,U01ES026721

Sci Rep (2020 09 01) 32873817

2020

DNA polymerase δ proofreads errors made by DNApolymerase ε.

Bulock, Chelsea R;Xing, Xuanxuan;Shcherbakova, Polina V


32123096

2020

DNA-protein crosslinks are repaired via homologousrecombination in mammalian mitochondria.

Chesner, Lisa N;Essawy, Maram;Warner, Cecilia;Campbell, Colin

R01ES023350 DNA Repair (Amst) (2020Nov 25)

33316746

2020

Dual genome-wide CRISPR knockout and CRISPRactivation screens identify mechanisms that regulatethe ...

Schleicher, Emily M;Dhoonmoon, Ashna;Jackson, Lindsey M;Clements, Kristen E;Stump, Coryn L; ...

R01ES026184 PLoS Genet (2020 11) 33137164

2020

Dynamic action of DNA repair proteins as revealed bysingle molecule techniques: Seeing is believing ...

Kong, Muwen;Beckwitt, Emily C; VanHouten, Bennett


33087275

2020

Dynamic single-cell intracellular pH sensing using aSERS-active nanopipette.

Guo, Jing; SesenaRubfiaro, Alberto; Lai,Yanhao; Moscoso,Joseph; Chen, Feng;Liu, Yuan; Wang ...

R01ES023569 Analyst (2020 Jul 21) 32542257

2020

Dysregulations of Functional RNA Modifications inCancer, Cancer Stemness and Cancer Therapeutics.

Uddin, MohammadBurhan; Wang,Zhishan; Yang,Chengfeng

R01ES026151,R01ES028256,R01ES029496,R01ES029942

Theranostics (2020) 32194861

2020

Efficient Estimation and Applications ofCross-Validated Genetic Predictions to Polygenic RiskScore ...

Mefford, Joel; Park,Danny; Zheng, Zhili;Ko, Arthur;Ala-Korpela, Mika;Laakso, Markku; Pajuk...

R01ES029929 J Comput Biol (2020 04) 32077750

2020

Elagolix Treatment for Up to 12 Months in WomenWith Heavy Menstrual Bleeding and UterineLeiomyomas ...

Simon, James A;Al-Hendy, Ayman;Archer, David F;Barnhart, Kurt T;Bradley, Linda D; Carr,Br ...

R01ES028615 Obstet Gynecol (2020 06) 32459423

2020

Electron microscopic characterization of exhaustparticles containing lead dibromide beads expelled ...

Griffith, Jack D R01ES031635 Atmos Pollut Res (2020Sep)

33100835

2020

Endogenous itaconate is not required for particulatematter-induced NRF2 expression or inflammatory ...

Sun, Kaitlyn A; Li,Yan; Meliton, AngeloY; Woods, Parker S;Kimmig, Lucas M;Cetin-Atalay, Re ...

P30ES027792,R01ES015024,U01ES026718

Elife (2020 Apr 07) 32255424

2020

Engineered unnatural ubiquitin for optimal detectionof deubiquitinating enzymes.

Rut, Wioletta;Zmudzinski, Mikolaj;Snipas, Scott J; Bekes,Miklos; Huang, Tony T;Drag, Marci ...

R01ES025166 Chem Sci (2020 Jun 21) 32953009

2020

Environmental determinants of cardiovascular disease:lessons learned from air pollution.

Al-Kindi, Sadeer G;Brook, Robert D;Biswal, Shyam;Rajagopalan, Sanjay

R01ES019616,U01ES026721

Nat Rev Cardiol (2020 10) 32382149

2020

Environmental Obesogens and Their Impact onSusceptibility to Obesity: New Mechanisms andChemicals.

Egusquiza, RiannJenay; Blumberg, Bruce

R01ES023316,R01ES023316

Endocrinology (2020 0301)

32067051

2020

Environmental Pollution and the DevelopmentalOrigins of Childhood Liver Disease.

Cave, Matthew C P30ES030283,P42ES023716,R21ES031510,R35ES028373,R35ES028373

Hepatology (2020 Nov) 32910501

2020

Epigenetic transgenerational inheritance ofparent-of-origin allelic transmission of outcross pathol...

Ben Maamar, Millissia;King, Stephanie E;Nilsson, Eric; Beck,Daniel; Skinner,Michael K

R01ES012974,R01ES012974

Dev Biol (2020 02 01) 31682807

2020

Epigenome environment interactions accelerateepigenomic aging and unlock metabolically restricted e...

Treviño, Lindsey S;Dong, Jianrong;Kaushal, Ahkilesh;Katz, Tiffany A; Jangid,Rahul Kumar; Ro ...

P30ES030285,U01ES026719

Nat Commun (2020 05 08) 32385268

2020

Epigenome-wide association study fortransgenerational disease sperm epimutationbiomarkers followin ...

Ben Maamar, Millissia;Nilsson, Eric; Thorson,Jennifer L M; Beck,Daniel; Skinner,Michael K

R01ES012974,R01ES012974

Reprod Toxicol (2020Dec)

32905848

2020

Epigenomics and genotype-phenotype associationanalyses reveal conserved genetic architecture of com...

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Reference Standardization for Quantification andHarmonization of Large-Scale Metabolomics.

Liu, Ken H; Nellis,Mary; Uppal, Karan;Ma, Chunyu; Tran,ViLinh; Liang,Yongliang; Walker, D...

P30ES019776,R01ES023485,U2CES030163

Anal Chem (2020 07 07) 32490663

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Regenerating zebrafish fin epigenome is characterizedby stable lineage-specific DNA methylation and ...

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U24ES026699 Genome Biol (2020 02 27) 32106888

2020

Regulation and pharmacological targeting of RAD51in cancer.

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R01ES030335 NAR Cancer (2020 Sep) 33015624

2020

Remarkable Enhancement of Nucleotide ExcisionRepair of a Bulky Guanine Lesion in a CovalentlyClose ...

Kolbanovskiy, Marina;Aharonoff, Abraham;Sales, Ana Helena;Geacintov, Nicholas E;Shafirovich, ...

R01ES027059 Biochemistry (2020 Aug11)

32786887

2020

Requisite Chromatin Remodeling for Myeloid andErythroid Lineage Differentiation fromErythromyeloid ...

Wu, Jun; Krchma,Karen; Lee, Hyung Joo;Prabhakar, Sairam;Wang, Xiaoli; Zhao,Haiyong; Xing, ...

U24ES026699 Cell Rep (2020 Nov 17) 33207205

2020

Research Participants' Attitudes towards ReceivingInformation on Genetic Susceptibility to Arsenic ...

Tamayo, Lizeth I; Lin,Hannah; Ahmed,Alauddin; Shahriar,Hasan; Hasan, Rabiul;Sarwar, Golam; ...

P30ES027792,P42ES010349,R24ES028532,R35ES028379

Public Health Genomics(2020)

32069464

2020

REV1 inhibitor JH-RE-06 enhances tumor cellresponse to chemotherapy by triggering senescencehallma ...

Chatterjee, Nimrat;Whitman, Matthew A;Harris, Cynthia A; Min,Sophia M; Jonas,Oliver; Lien, ...

P30ES002109,R35ES028303


33168727

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Rev7 loss alters cisplatin response and increases drugefficacy in chemotherapy-resistant lung cance ...

Vassel, Faye-Marie;Bian, Ke; Walker,Graham C; Hemann,Michael T

P30ES002109,R35ES028303,T32ES007020


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Ribonucleotide incorporation in yeast genomic DNAshows preference for cytosine and guanosine preced ...

Balachander, Sathya;Gombolay, Alli L;Yang, Taehwan; Xu,Penghao; Newnam,Gary; Keskin, Havva ...

R01ES026243 Nat Commun (2020 05 15) 32415081

2020

Robust principal component analysis for accurateoutlier sample detection in RNA-Seq data.

Chen, Xiaoying; Zhang,Bo; Wang, Ting; Bonni,Azad; Zhao, Guoyan

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Role of Isocitrate Dehydrogenase 2 on DNAHydroxymethylation in Human Airway SmoothMuscle Cells.

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R01ES024784 Am J Respir Cell Mol Biol(2020 07)

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Role of Nucleotide Excision Repair in CisplatinResistance.

Duan, Mingrui;Ulibarri, Jenna; Liu, KeJian; Mao, Peng

R01ES030993,R21ES029302

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Roles for MDC1 in cancer development and treatment.

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Seasonally variant gene expression in full-term humanplacenta.

Clarkson-Townsend,Danielle A; Kennedy,Elizabeth; Everson,Todd M; Deyssenroth,Maya A; Burt, ...

P30ES019776,R01ES025145,R01ES025145,R24ES028507,T32ES012870

FASEB J (2020 Aug) 32574425

2020

Semisynthesis of the Organoarsenical AntibioticArsinothricin.

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R01ES023779 J Nat Prod (2020 09 25) 32830503

2020

Sex-dependent effects of preconception exposure toarsenite on gene transcription in parental germ c ...

Venkatratnam,Abhishek; Douillet,Christelle; Topping,Brent C; Shi, Qing;Addo, Kezia A; Idera ...

P42ES031007,R01ES028721,R01ES028721,R01ES029925

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Single-molecule live-cell imaging revealsRecB-dependent function of DNA polymerase IVin double str ...

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Structural basis for STAT2 suppression by flavivirusNS5.

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Structural biology of DNA abasic site protection bySRAP proteins.

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Structural insights into the promutagenic bypass of themajor cisplatin-induced DNA lesion.

Ouzon-Shubeita, Hala;Vilas, Caroline K; Lee,Seongmin

R01ES026676 Biochem J (2020 03 13) 32039434

2020

TCDD-induced multi- and transgenerational changes inthe methylome of male zebrafish gonads.

Akemann, Camille;Meyer, Danielle N;Gurdziel, Katherine;Baker, Tracie R

F31ES030278,F31ES030278,P30ES020957,R01ES030722,R01ES030722

Environ Epigenet (2020) 33214906

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Tethering-facilitated DNA 'opening' andcomplementary roles of β-hairpin motifs in theRad4/XPC DNA ...

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TGF-β Promotes Metabolic Reprogramming in LungFibroblasts via mTORC1-dependent ATF4 Activation.

O'Leary, Erin M; Tian,Yufeng; Nigdelioglu,Recep; Witt, Leah J;Cetin-Atalay, Rengul;Meliton, ...

U01ES026718 Am J Respir Cell Mol Biol(2020 11)

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The antitumorigenic roles of BRCA1-BARD1 in DNArepair and replication.

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R01ES007061 Nat Rev Mol Cell Biol(2020 05)

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The association between neuraxial anesthesia and thedevelopment of childhood asthma - a secondary a ...

Huang, Yueyang;Tzeng, Jung-Ying;Maguire, Rachel; Hoyo,Cathrine; Allen,Terrence

P30ES025128,R24ES028531

Curr Med Res Opin (202006)

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The cadmium-responsive gene, cdr-6, does notinfluence Caenorhabditis elegans responses toexogenous ...

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The conserved DNMT1-dependent methylationregions in human cells are vulnerable to neurotoxicantrot ...

Freeman, Dana M; Lou,Dan; Li, Yanqiang;Martos, Suzanne N;Wang, Zhibin

R01ES025761,R01ES025761,U01ES026721

Epigenetics Chromatin(2020 03 16)

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The DNA-binding activity of USP1-associated factor 1is required for efficient RAD51-mediated homolo ...

Liang, Fengshan;Miller, Adam S; Tang,Caroline; Maranon,David; Williamson,Elizabeth A; Hroma ...

R01ES007061 J Biol Chem (2020 06 12) 32350107

2020

The Evolution of Variance Control. Bruijning, Marjolein;Metcalf, C Jessica E;Jongejans, Eelke;Ayroles, Julien F

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The Gene scb-1 Underlies Variation in Caenorhabditiselegans Chemotherapeutic Responses.

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R01ES029930 G3 (Bethesda) (2020 0707)

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The Great Oxidation Event expanded the geneticrepertoire of arsenic metabolism and cycling.

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The involvement of nucleotide excision repair proteinsin the removal of oxidative DNA damage.

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The ligation of pol β mismatch insertion productsgoverns the formation of promutagenic base excisio ...

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The multifaceted role of PARP1 in RNA biogenesis. Eleazer, Rebekah;Fondufe-Mittendorf,Yvonne N

R01ES024478 Wiley Interdiscip RevRNA (2020 Jul 12)

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The Pseudomonas putida NfnB nitroreductase confersresistance to roxarsone.

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2020

The qBED track: a novel genome browservisualization for point processes.

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The role of endocrine-disrupting chemicals in uterinefibroid pathogenesis.

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R01ES028615 Curr Opin EndocrinolDiabetes Obes (2020 12)

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The role of environmental exposures and theepigenome in health and disease.

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P30ES017885,T32ES007062,U01ES026697


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The Role of Hedgehog Pathway in Female Cancers. Garcia, Natalia; Ulin,Mara; Al-Hendy,Ayman; Yang, Qiwei

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The roles of polymerases ν and θ in replicative bypassof O6- and N2-alkyl-2'-deoxyguanosine lesions ...

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R01ES029749 J Biol Chem (2020 04 03) 32098870

2020

The Selective Progesterone Receptor ModulatorUlipristal Acetate Inhibits the Activity of the Glucoc ...

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Tissue-Resident Alveolar Macrophages Do Not Relyon Glycolysis for LPS-induced Inflammation.

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P30ES027792,R01ES015024,U01ES026718

Am J Respir Cell Mol Biol(2020 02)

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Tissue-specific usage of transposable element-derivedpromoters in mouse development.

Miao, Benpeng; Fu,Shuhua; Lyu, Cheng;Gontarz, Paul; Wang,Ting; Zhang, Bo

U24ES026699 Genome Biol (2020 09 28) 32988383

2020

TM3'seq: A Tagmentation-Mediated 3' SequencingApproach for Improving Scalability of RNAseqExperime ...

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ToxPoint: Dissecting Functional RNA Modificationsin Responses to Environmental Exposure-Mechanistic...

Yang, Chengfeng R01ES026151,R01ES029942

Toxicol Sci (2020 03 01) 32101319

2020

Translesion synthesis of 6-nitrochrysene-derived2'-deoxyadenosine adduct in human cells.

Powell, Brent V;Bacurio, Jan Henric T;Basu, Ashis K


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Translesion synthesis of the major nitrogenmustard-induced DNA lesion by human DNApolymerase η.

Jung, Hunmin; Rayala,Naveen Kumar; Lee,Seongmin

R01ES026676 Biochem J (2020 12 11) 33175093

2020

Trinucleotide repeat instability via DNA base excisionrepair.

Lai, Yanhao; Beaver,Jill M; Laverde,Eduardo; Liu, Yuan


33087278

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Tumor-Targeted, Cytoplasmic Delivery of Large,Polar Molecules Using a pH-Low Insertion Peptide.

Svoronos, Alexander A;Bahal, Raman; Pereira,Mohan C; Barrera,Francisco N; Deacon,John C; Bo ...

R01ES005775 Mol Pharm (2020 02 03) 31855437

2020

Twenty years of t-loops: A case study for theimportance of collaboration in molecular biology.

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R01ES031635 DNA Repair (Amst) (2020Oct)

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2020

Ubiquitinated-PCNA protects replication forks fromDNA2-mediated degradation by regulating Okazaki f...

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R01ES026184 Nat Commun (2020 05 01) 32358495

2020

Unhooking of an interstrand cross-link at DNA forkstructures by the DNA glycosylase NEIL3.

Imani Nejad, Maryam;Housh, Kurt;Rodriguez, Alyssa A;Haldar, Tuhin; Kathe,Scott; Wallace, S ...


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Using Genetic and Species Diversity to Tackle KidneyDisease.

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R01ES029916 Trends Genet (2020 07) 32362446

2020

USP7-mediated deubiquitination differentiallyregulates CSB but not UVSSA upon UVradiation-induced ...

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R01ES012991 Cell Cycle (2020 01) 31775559

2020

Uterine fibroids in menopause and perimenopause. Ulin, Mara; Ali,Mohamed; Chaudhry,Zunir Tayyeb;Al-Hendy, Ayman;Yang, Qiwei

R01ES028615 Menopause (2020 02) 31834160

2020

Variable impact of conformationally distinct DNAlesions on nucleosome structure and dynamics: Impli...

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Vinyl Chloride and High-Fat Diet as a Model ofEnvironment and Obesity Interaction.

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R21ES031531 J Vis Exp (2020 01 12) 31984951

2020

Vitamin D and uterine fibroids: preclinical evidence isin; time for an overdue clinical study!

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R01ES028615 Fertil Steril (2020 01) 32033736

2020

What Is Lost in the Weismann Barrier? Bline, Abigail P; LeGoff, Anne; Allard,Patrick

R01ES027487,R01ES027487

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2020

YTHDF2 Binds to 5-Methylcytosine in RNA andModulates the Maturation of Ribosomal RNA.

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R01ES025121,T32ES018827

Anal Chem (2020 01 07) 31815440

2020

YY1 interacts with guanine quadruplexes to regulateDNA looping and gene expression.

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R35ES031707,T32ES018827

Nat Chem Biol (2020 Nov16)

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1,25 Dihydroxyvitamin D3 Enhances the AntifibroidEffects of Ulipristal Acetate in Human Uterine Fib ...


R01ES028615 Reprod Sci (2019 06) 30514160

2019

1HN, 13C, and 15N backbone resonance assignmentsof the human DNA ligase 3 DNA-binding domain(resid ...

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1HN, 13C, and 15N resonance assignments of humancalmodulin bound to a peptide derived from the STRA...

Varney, Kristen M;Wilder, Paul T;Godoy-Ruiz, Raquel;Mancia, Filippo; Weber,David J

R01ES012512 Biomol NMR Assign(2019 10)

30875027

2019

5',8-Cyclopurine Lesions in DNA Damage: Chemical,Analytical, Biological, and Diagnostic Significanc ...

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R01ES023569,R01ES027059

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5-Formylcytosine-induced DNA-peptide cross-linksreduce transcription efficiency, but do not cause t ...

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R01ES023350,R01ES025987

J Biol Chem (2019 11 29) 31597704

2019

A missense variant in FTCD is associated with arsenicmetabolism and toxicity phenotypes in Banglade ...

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P30ES009089,P30ES027792,P42ES010349,R24ES028532,R35ES028379

PLoS Genet (2019 03) 30893314

2019

A non-randomized procedure for large-scaleheterogeneous multiple discrete testing based onrandomiz ...

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2019

A Novel Gene Underlies Bleomycin-ResponseVariation in Caenorhabditis elegans.

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2019

A parametric meta-analysis. Yu, Chang; Zelterman,Daniel

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2019

A Preliminary Study: Human Fibroid Stro-1+/CD44+Stem Cells Isolated From Uterine Fibroids Demonstra...

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R01ES028615 Reprod Sci (2019 05) 29954254

2019

A recurrent cancer-associated substitution in DNApolymerase ε produces a hyperactive enzyme.

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2019

A Small Molecule Targeting Mutagenic TranslesionSynthesis Improves Chemotherapy.

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R01ES028865,R01ES028865,R35ES028303

Cell (2019 06 27) 31178121

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A two-stage phase II clinical trial design with nestedcriteria for early stopping and efficacy.

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Pharm Stat (2019 11) 31507079

2019

A White-Box Machine Learning Approach forRevealing Antibiotic Mechanisms of Action.

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R35ES028303 Cell (2019 05 30) 31080069

2019

Aberrant Activation of β-Catenin Signaling DrivesGlioma Tumorigenesis via USP1-Mediated Stabilizati...

Ma, Li; Lin, Kangyu;Chang, Guoqiang;Chen, Yiwen; Yue,Chen; Guo, Qing;Zhang, Sicong; Jia, ...

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2019

Accelerating cancer without mutations. Brash, Douglas E R01ES030562 Elife (2019 03 21) 30895924

2019 Accurate ethnicity prediction from placental DNAmethylation data.

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R01ES025145,R01ES025145,R24ES028507


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Acute effects of air pollution on mortality: A 17-yearanalysis in Kuwait.

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R00ES027511 Environ Int (2019 05) 30844583

2019

Addendum: Ribose-seq: global mapping ofribonucleotides embedded in genomic DNA.

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R01ES026243 Nat Methods (2019 08) 31324896

2019

Aflatoxin-Guanine DNA Adducts and OxidativelyInduced DNA Damage in Aflatoxin-Treated Mice inVivo a ...

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Aging-like Spontaneous Epigenetic SilencingFacilitates Wnt Activation, Stemness, andBrafV600E-Indu ...

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R01ES011858 Cancer Cell (2019 02 11) 30753828

2019

AID-RNA polymerase II transcription-dependentdeamination of IgV DNA.

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Air Pollution, Asthma, and Sleep Apnea: NewEpidemiological Links?

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P30ES027792,R01ES015024,U01ES026718

Ann Am Thorac Soc (2019Mar)

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Air pollution-derived particulate matter dysregulateshepatic Krebs cycle, glucose and lipid metabol ...

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P30ES026529,U01ES026721

Sci Rep (2019 11 22) 31757983

2019

Arsinothricin, an arsenic-containing non-proteinogenicamino acid analog of glutamate, is a broad-sp ...

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2019

Arsinothricin, an arsenic-containing non-proteinogenicamino acid analog of glutamate, is a broad-sp ...

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2019

Association between gestational urinary bisphenol aconcentrations and adiposity in young children: ...

Braun, Joseph M; Li,Nan; Arbuckle, Tye E;Dodds, Linda;Massarelli, Isabelle;Fraser, William ...

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2019

Association of a Pathway-Specific Genetic Risk ScoreWith Risk of Radiation-Associated Contralateral ...

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Association of Arsenic Exposure with Whole BloodDNA Methylation: An Epigenome-Wide Study ofBanglad ...

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P30ES009089,P30ES027792,P42ES010349,R24ES028532,R35ES028379

Environ Health Perspect(2019 05)

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Associations of Benzo(ghi)perylene andHeptachlorodibenzo-p-dioxin in Serum of ServicePersonnel Dep ...

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P30ES019776,R01ES023485,U2CES030163

J Occup Environ Med(2019 12)

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Associations of cord blood leptin and adiponectin withchildren's cognitive abilities.

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R01ES025214 Psychoneuroendocrinology(2019 01)

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Associations of serum perfluoroalkyl substance andvitamin D biomarker concentrations in NHANES, 200...

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Benzo[a]pyrene Perturbs Mitochondrial and AminoAcid Metabolism in Lung Epithelial Cells and Has Sim...

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P30ES019776,R01ES023485


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2019

Bioactivation of the tobacco carcinogens4-aminobiphenyl (4-ABP) and2-amino-9H-pyrido[2,3-b]indole ...

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Biological Evaluation of DNA Biomarkers in aChemically Defined and Site-Specific Manner.

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2019

Blood Leukocyte DNA Methylation Predicts Risk ofFuture Myocardial Infarction and Coronary Heart Dis...

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Circulation (2019 08 20) 31424985

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BPA interferes with StAR-mediated mitochondrialcholesterol transport to induce germline dysfunction ...

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Burden of Uterine Fibroids: An African Perspective, ACall for Action and Opportunity for Interventi ...

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Bypass of the Major Alkylative DNA Lesion byHuman DNA Polymerase η.

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2019

Cadmium and High-Fat Diet Disrupt Renal, Cardiacand Hepatic Essential Metals.

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Defining UHRF1 Domains that Support Maintenanceof Human Colon Cancer DNA Methylation andOncogenic ...

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N-Acetylcysteine: Antioxidant, Aldehyde Scavenger,and More.

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31046246

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Natural variation in C. elegans arsenic toxicity isexplained by differences in branched chain amino ...

Zdraljevic, Stefan; Fox,Bennett William;Strand, Christine;Panda, Oishika; Tenjo,Francisco J ...

R01ES029930 Elife (2019 04 08) 30958264

2019

Neonatal Adipocytokines and Longitudinal Patterns ofChildhood Growth.

Buck, Catherine O;Eliot, Melissa N;Kelsey, Karl T; Chen,Aimin; Kalkwarf,Heidi; Lanphear, B ...

R01ES025214 Obesity (Silver Spring)(2019 08)

31199076

2019

Nickel-induced transcriptional changes persist postexposure through epigenetic reprogramming.

Jose, Cynthia C; Wang,Zhenjia; Tanwar, VinaySingh; Zhang, Xiaoru;Zang, Chongzhi;Cuddapah, ...

P30ES000260,R01ES024727


31856895

2019

NuA4 acetyltransferase is required for efficientnucleotide excision repair in yeast.

Hodges, Amelia J;Plummer, Dalton A;Wyrick, John J


30473425

2019

Nucleotide Excision Repair and Impact ofSite-Specific 5',8-Cyclopurine and Bulky DNALesions on the ...

Shafirovich, Vladimir;Kolbanovskiy, Marina;Kropachev, Konstantin;Liu, Zhi; Cai, Yuquin;Terz ...


2019

Nucleotide excision repair capacity increases duringdifferentiation of human embryonic carcinoma ce ...

Li, Wentao; Liu,Wenjie; Kakoki,Ayano; Wang, Rujin;Adebali, Ogun; Jiang,Yuchao; Sancar, Az ...

P30ES010126,R01ES027255

J Biol Chem (2019 04 12) 30808711

2019

Organization of DNA damage, excision repair, andmutagenesis in chromatin: A genomic perspective.

Mao, Peng; Wyrick,John J

R01ES028698,R21ES029302,R21ES029655


31307926

2019

Overall gestational weight gain mediates therelationship between maternal and child obesity.

Josey, Michele J;McCullough, Lauren E;Hoyo, Cathrine;Williams-DeVane,ClarLynda

R24ES028531 BMC Public Health (2019Aug 07)

31391077

2019

Overexpression of hsa-miR-186 induces chromosomalinstability in arsenic-exposed human keratinocytes ...

Wu, Jiguo; FerragutCardoso, Ana P; States,Vanessa A R;Al-Eryani, Laila; Doll,Mark; Wise, S ...


31176655

2019

p53 activation by Cr(VI): a transcriptionally limitedresponse induced by ATR kinase in S-phase.

Luczak, Michal W;Krawic, Casey;Zhitkovich, Anatoly

R01ES008786,R01ES028072

Toxicol Sci (2019 Aug 06) 31388677

2019

Pach-ing It in: The Peculiar Organization ofMammalian Pachytene Chromosomes.

Jung, Yoon Hee;Corces, Victor G

R01ES027859,R01ES027859

Mol Cell (2019 02 07) 30735652

2019

PARP1 is a versatile factor in the regulation of mRNAstability and decay.

Matveeva, Elena A;Mathbout, Lein F;Fondufe-Mittendorf,Yvonne N

R01ES024478 Sci Rep (2019 03 06) 30842529

2019

Pathways of arsenic uptake and efflux. Garbinski, Luis D;Rosen, Barry P; Chen,Jian

R01ES023779 Environ Int (2019 05) 30852446

2019

Phytochelatin database: a resource for phytochelatincomplexes of nutritional and environmental meta ...

Dennis, Kristine K;Uppal, Karan; Liu, KenH; Ma, Chunyu; Liang,Bill; Go, Young-Mi;Jones, D ...

P30ES019776,R01ES023485,U2CES030163

Database (Oxford) (201901 01)

31267134

2019

POLE proofreading defects: Contributions tomutagenesis and cancer.

Park, Vivian S; Pursell,Zachary F


30818169

2019

Population-Based Analysis of DNA Damage andEpigenetic Effects of 1,3-Butadiene in the Mouse.

Lewis, Lauren;Borowa-Mazgaj,Barbara; de Conti,Aline; Chappell, GraceA; Luo, Yu-Syuan;Bodna ...


30990016

2019

Prenatal and childhood exposure to poly- andperfluoroalkyl substances (PFAS) and cognitivedevelopm ...

Vuong, Ann M; Yolton,Kimberly; Xie,Changchun; Dietrich,Kim N; Braun, JosephM; Webster, Gle ...

P30ES006096,R01ES025214,T32ES010957

Environ Res (2019 05) 30818233

2019

Prenatal Bisphenol A Exposure in Mice InducesMultitissue Multiomics Disruptions Linking toCardiome ...

Shu, Le; Meng,Qingying; Diamante,Graciel; Tsai, Brandon;Chen, Yen-Wei;Mikhail, Andrew; Luk...

R01ES027487,R01ES027487


30566610

2019

Probing the Effect of Bulky Lesion-InducedReplication Fork Conformational Heterogeneity Using4-Ami ...

Cai, Ang; Bian, Ke;Chen, Fangyi; Tang, Qi;Carley, Rachel; Li,Deyu; Cho, Bongsup P

R01ES028865,R01ES028865

Molecules (2019 Apr 20) 31009995

2019

Processing of N5-substituted formamidopyrimidineDNA adducts by DNA glycosylases NEIL1 andNEIL3.

Minko, Irina G;Christov, Plamen P; Li,Liang; Stone, MichaelP; McCullough,Amanda K; Lloyd, ...


30448017

2019

Promutagenicity of 8-Chloroguanine, A MajorInflammation-Induced Halogenated DNA Lesion.

Kou, Yi; Koag,Myong-Chul; Lee,Seongmin

R01ES026676 Molecules (2019 Sep 27) 31569643

2019

Protection of abasic sites during DNA replication by astable thiazolidine protein-DNA cross-link.

Thompson, Petria S;Amidon, Katherine M;Mohni, Kareem N;Cortez, David;Eichman, Brandt F


31235915

2019

Quantification of DNA Lesions Induced by4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol inMammalian ...

Guo, Su; Leng, Jiapeng;Tan, Ying; Price,Nathan E; Wang,Yinsheng

R01ES025121,T32ES018827


30714728

2019

R-loop formation by dCas9 is mutagenic inSaccharomyces cerevisiae.

Laughery, Marian F;Mayes, Hannah C;Pedroza, Ivan K;Wyrick, John J


30590793

2019

Rad52 Restrains Resection at DNA Double-StrandBreak Ends in Yeast.

Yan, Zhenxin; Xue,Chaoyou; Kumar,Sandeep; Crickard, JBrooks; Yu, Yang;Wang, Weibin; Pham,...

R01ES007061 Mol Cell (2019 12 05) 31542296

2019

Random Walk Enzymes: Information Theory,Quantum Isomorphism, and Entropy Dispersion.

Mak, Chi H; Pham,Phuong; Goodman,Myron F

R35ES028343 J Phys Chem A (2019 Apr04)

30848911

2019

Recurrent Noncoding Mutations in Skin Cancers: UVDamage Susceptibility or Repair Inhibition as Prim ...

Roberts, Steven A;Brown, Alexander J;Wyrick, John J

R01ES028698,R21ES029302

Bioessays (2019 03) 30801747

2019

Redox Systems Biology of Nutrition and OxidativeStress.

Dennis, Kristine K; Go,Young-Mi; Jones, DeanP

P30ES019776,R01ES023485

J Nutr (2019 04 01) 30949678

2019

Regulatory control of Sgs1 and Dna2 duringeukaryotic DNA end resection.

Xue, Chaoyou; Wang,Weibin; Crickard, JBrooks; Moevus,Corentin J; Kwon,Youngho; Sung, Patri ...


30850524

2019

Repair and translesion synthesis of O6-alkylguanineDNA lesions in human cells.

Du, Hua; Wang,Pengcheng; Li, Lin;Wang, Yinsheng

R01ES025121 J Biol Chem (2019 07 19) 31167778

2019

Replication Stress and Consequential Instability of theGenome and Epigenome.

Tsegay, Pawlos S; Lai,Yanhao; Liu, Yuan

R01ES023569 Molecules (2019 Oct 27) 31717862

2019

Replication-Coupled DNA Repair. Cortez, David R01ES030575 Mol Cell (2019 06 06) 31173722

2019 Ribose-Map: a bioinformatics toolkit to mapribonucleotides embedded in genomic DNA.

Gombolay, Alli L;Vannberg, Fredrik O;Storici, Francesca


30272244

2019

Ribosomal DNA and the Nucleolus as Keystones ofNuclear Architecture, Organization, and Function.

Cerqueira, Amanda V;Lemos, Bernardo

R01ES027981 Trends Genet (2019 10) 31447250

2019

Ribosomal DNA harbors an evolutionarily conservedclock of biological aging.

Wang, Meng; Lemos,Bernardo

P30ES000002,R01ES027981

Genome Res (2019 03) 30765617

2019

Role of CTCF in DNA damage response. Tanwar, Vinay Singh;Jose, Cynthia C;Cuddapah, Suresh

P30ES000260,R01ES024727

Mutat Res (2019 Apr -Jun)

31395350

2019

Role of RNase H enzymes in maintaining genomestability in Escherichia coli expressing a steric-gate ...

Walsh, Erin; Henrikus,Sarah S; Vaisman,Alexandra;Makiela-Dzbenska,Karolina; Armstrong,Thom ...


31543434

2019

Role of Y-family translesion DNA polymerases inreplication stress: Implications for new cancer ther ...

Tonzi, Peter; Huang,Tony T


30954011

2019

Rotational and translational positions determine thestructural and dynamic impact of a single ribon ...

Fu, Iwen; Smith,Duncan J; Broyde, Suse


30522887

2019

Sense and sensibility: ATM oxygen stress signalingmanages brain cell energetics.

Schlacher, Katharina R01ES029680 J Cell Biol (2019 03 04) 30782782

2019

Sex-specific differences in genotoxic and epigeneticeffects of 1,3-butadiene among mouse tissues.

Lewis, Lauren;Chappell, Grace A;Kobets, Tetyana;O'Brian, Bridget E;Sangaraju, Dewakar;Kosy ...

P30ES029067,R01ES029911

Arch Toxicol (2019 03) 30552462

2019

Short-term ambient particle radioactivity level andrenal function in older men: Insight from the No ...

Gao, Xu; Koutrakis,Petros; Blomberg,Annelise J; Coull,Brent; Vokonas, Pantel;Schwartz, Joe ...

P30ES009089,R01ES025225,R01ES027747

Environ Int (2019 10) 31336254

2019

Simple CRISPR-Cas9 Genome Editing inSaccharomyces cerevisiae.

Laughery, Marian F;Wyrick, John J

R01ES028698,R21ES029302,R21ES029655

Curr Protoc Mol Biol(2019 12)

31763795

2019

Single-molecule visualization of human BLM helicaseas it acts upon double- and single-stranded DNA ...

Xue, Chaoyou; Daley,James M; Xue, Xiaoyu;Steinfeld, Justin; Kwon,Youngho; Sung,Patrick; Gr ...


31544923

2019

Single-nucleotide resolution analysis of nucleotideexcision repair of ribosomal DNA in humans and m ...

Yang, Yanyan; Hu,Jinchuan; Selby,Christopher P; Li,Wentao; Yimit, Askar;Jiang, Yuchao; San ...

P30ES010126,R01ES027255

J Biol Chem (2019 01 04) 30413533

2019

SLIRP Interacts with Helicases to Facilitate2'-O-Methylation of rRNA and to Promote Translation.

Li, Lin; Miao, Weili;Williams, Preston; Guo,Cheng; Wang,Yinsheng

R01ES025121 J Am Chem Soc (2019 0717)

31260285

2019

Snacking frequency and dietary intake in toddlers andpreschool children.

Xue, Hong; Maguire,Rachel L; Liu, Jin;Kollins, Scott H;Murphy, Susan K;Hoyo, Cathrine; Fue ...

P30ES025128,R24ES028531

Appetite (2019 11 01) 31302102

2019

Sperm epimutation biomarkers of obesity andpathologies following DDT induced epigenetictransgenera ...

King, Stephanie E;McBirney, Margaux;Beck, Daniel;Sadler-Riggleman,Ingrid; Nilsson, Eric;Sk ...

R01ES012974,R01ES012974

Environ Epigenet (2019Apr)

31186947

2019

Statistical Approaches for Investigating Periods ofSusceptibility in Children's Environmental Healt ...

Buckley, Jessie P;Hamra, Ghassan B;Braun, Joseph M

R01ES025214,R01ES027408


30684243

2019

Structural basis for the bypass of the majoroxaliplatin-DNA adducts by human DNA polymeraseη.

Ouzon-Shubeita, Hala;Baker, Meghan; Koag,Myong-Chul; Lee,Seongmin

R01ES026676 Biochem J (2019 02 28) 30709915

2019

Structural consequence of the most frequentlyrecurring cancer-associated substitution in DNApolyme ...

Parkash, Vimal;Kulkarni, Yashraj; TerBeek, Josy;Shcherbakova, PolinaV; Kamerlin, ShinaCaro ...

R01ES015869 Nat Commun (2019 01 22) 30670696

2019

Structure and mechanism of pyrimidine-pyrimidone(6-4) photoproduct recognition by the Rad4/XPC nucl...

Paul, Debamita; Mu,Hong; Zhao, Hong;Ouerfelli, Ouathek;Jeffrey, Philip D;Broyde, Suse; Min ...


31106376

2019

SUMOning the base excision repair machinery fordifferentiation.

Wiest, Nathaniel E;Tomkinson, Alan E

R01ES012512 EMBO J (2019 01 03) 30545824

2019

Synthesis and Characterization of Site-Specific O6-Alkylguanine DNA-Alkyl Transferase-Oligonucleoti...

Ghodke, Pratibha P;Albertolle, Matthew E;Johnson, Kevin M;Guengerich, F Peter

R01ES010546,R01ES026955,T32ES007028

Curr Protoc Nucleic AcidChem (2019 03)

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2019

Targeted and Persistent 8-Oxoguanine Base Damage atTelomeres Promotes Telomere Loss and Crisis.

Fouquerel, Elise;Barnes, Ryan P; Uttam,Shikhar; Watkins,Simon C; Bruchez,Marcel P; Opresko, ...

R00ES027028,R33ES025606

Mol Cell (2019 07 11) 31101499

2019

Targeted Quantitative Proteomic Approach forHigh-Throughput Quantitative Profiling of SmallGTPases ...

Huang, Ming; Darvas,Martin; Keene, C Dirk;Wang, Yinsheng

R01ES025121,T32ES018827

Anal Chem (2019 10 01) 31460748

2019

Targeted Quantitative Proteomics RevealedArsenite-induced Proteasomal Degradation of RhoB inFibrob ...

Tam, Lok Ming; Huang,Ming; Wang, Yinsheng

R01ES025121,T32ES018827


31140275

2019

Targeting phosphatases in cancer: suppression of manyversus the ablation of one.

D'Arcy, Brandon M;Prakash, Aishwarya;Honkanen, Richard E

R01ES030084,R01ES030084

Oncotarget (2019 Nov 12) 31762936

2019

The antibiotic action of methylarsenite is an emergentproperty of microbial communities.

Chen, Jian; Yoshinaga,Masafumi; Rosen,Barry P

R01ES023779 Mol Microbiol (2019 02) 30520200

2019

The BRCA Tumor Suppressor Network inChromosome Damage Repair by HomologousRecombination.

Zhao, Weixing; Wiese,Claudia; Kwon,Youngho; Hromas,Robert; Sung, Patrick

R01ES007061 Annu Rev Biochem (201906 20)

30917004

2019

The contribution of parent-to-offspring transmission oftelomeres to the heritability of telomere le ...

Delgado, Dayana A;Zhang, Chenan;Gleason, Kevin;Demanelis, Kathryn;Chen, Lin S; Gao,Jianju ...

P30ES027792,P42ES010349,R24ES028532,R35ES028379

Hum Genet (2019 Jan) 30536049

2019

The effect of age on DNA methylation in whole bloodamong Bangladeshi men and women.

Jansen, Rick J; Tong,Lin; Argos, Maria;Jasmine, Farzana;Rakibuz-Zaman,Muhammad; Sarwar,Go ...

P30ES027792,P42ES010349,R24ES028532,R35ES028379

BMC Genomics (2019 Sep10)

31506065

2019

The epigenomic landscape of transposable elementsacross normal human development and anatomy.

Pehrsson, Erica C;Choudhary, Mayank NK; Sundaram, Vasavi;Wang, Ting

U24ES026699 Nat Commun (2019 12 10) 31822674

2019

The Impact of Minor-GrooveN2-Alkyl-2'-deoxyguanosine Lesions on DNAReplication in Human Cells.

Wu, Jun; Du, Hua; Li,Lin; Price, Nathan E;Liu, Xiaochuan; Wang,Yinsheng

R01ES025121,T32ES018827

ACS Chem Biol (2019 0816)

31347832

2019

The Rad51 paralogs facilitate a novel DNA strandspecific damage tolerance pathway.

Rosenbaum, Joel C;Bonilla, Braulio;Hengel, Sarah R; Mertz,Tony M; Herken,Benjamin W; Kazemi ...

R01ES007061 Nat Commun (2019 08 05) 31383866

2019

The RecQ helicase Sgs1 drives ATP-dependentdisruption of Rad51 filaments.

Crickard, J Brooks;Xue, Chaoyou; Wang,Weibin; Kwon,Youngho; Sung,Patrick; Greene, Eric C


30916344

2019

The Role of Dynamic m6 A RNA Methylation inPhotobiology.

Robinson, Myles; Shah,Palak; Cui, Yan-Hong;He, Yu-Ying

P30ES027792,R01ES024373,R01ES030576

Photochem Photobiol(2019 01)

29729018

2019

Tightly linked antagonistic-effect loci underliepolygenic phenotypic variation in C. elegans.

Bernstein, Max R;Zdraljevic, Stefan;Andersen, Erik C;Rockman, Matthew V

R01ES029930 Evol Lett (2019 Oct) 31636939

2019

Transcription shapes DNA replication initiation andtermination in human cells.

Chen, Yu-Hung;Keegan, Sarah; Kahli,Malik; Tonzi, Peter;Fenyö, David; Huang,Tony T; Smith, ...


30598550

2019

Transcriptional Bypass of DNA-Protein andDNA-Peptide Conjugates by T7 RNA Polymerase.

Ji, Shaofei; Thomforde,Jenna; Rogers, Colette;Fu, Iwen; Broyde, Suse;Tretyakova, Natalia Y

R01ES023350,R01ES025987


31573793

2019

Transcriptome Analysis Reveals Distinct Responses toPhysiologic versus Toxic Manganese Exposure in ...

Fernandes, Jolyn;Chandler, Joshua D;Lili, Loukia N; Uppal,Karan; Hu, Xin; Hao,Li; Go, You ...

P30ES019776,R01ES023485

Front Genet (2019) 31396262

2019

Transgenerational effects of obesogens. Lee, Michelle Kira;Blumberg, Bruce

R01ES023316,R01ES023316

Basic Clin PharmacolToxicol (2019 Aug)

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2019

Transgenerational Self-Reconstruction of DisruptedChromatin Organization After Exposure To An Envir...

Diaz-Castillo, Carlos;Chamorro-Garcia,Raquel; Shioda, Toshi;Blumberg, Bruce

P30ES007048,R01ES023316,R01ES023316

Sci Rep (2019 09 10) 31506492

2019

Transgenerational sperm DNA methylationepimutation developmental origins following ancestralvinclo ...

Skinner, Michael K;Nilsson, Eric;Sadler-Riggleman,Ingrid; Beck, Daniel;Ben Maamar, Millissi ...

R01ES012974,R01ES012974

Epigenetics (2019 07) 31079544

2019

Transposable elements drive widespread expression ofoncogenes in human cancers.

Jang, Hyo Sik; Shah,Nakul M; Du, Alan Y;Dailey, Zea Z;Pehrsson, Erica C;Godoy, Paula M; Zh ...

U24ES026699 Nat Genet (2019 04) 30926969

2019

Unlike the Escherichia coli counterpart, archaealRNase HII cannot process ribose monophosphate abas...

Malfatti, MatildeClarissa; Henneke,Ghislaine; Balachander,Sathya; Koh, KyungDuk; Newnam, Ga ...

R01ES026243 J Biol Chem (2019 08 30) 31300556

2019

Using Collaborative Cross Mouse Population to FillData Gaps in Risk Assessment: A Case Study of Pop...

Luo, Yu-Syuan;Cichocki, Joseph A;Hsieh, Nan-Hung;Lewis, Lauren; Wright,Fred A; Threadgill, ...

P30ES029067,P42ES027704,R01ES029911


31246107

2019

Using phenome-wide association studies to examinethe effect of environmental exposures on human hea ...

Braun, Joseph M;Kalloo, Geetika;Kingsley, Samantha L;Li, Nan

R01ES025214,R01ES027408

Environ Int (2019 09) 31200158

2019

Virtual Pharmacophore Screening IdentifiesSmall-Molecule Inhibitors of the Rev1-CT/RIRProtein-Prot ...

Dash, Radha C; Ozen,Zuleyha; McCarthy,Kaitlyn R; Chatterjee,Nimrat; Harris, CynthiaA; Rizzo ...

P30ES002109,R35ES028303

ChemMedChem (2019 0904)

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2019

Vitamin C as a Modulator of the Response to CancerTherapy.

Blaszczak, Wiktoria;Barczak, Wojciech;Masternak, Julia;Kopczyński,Przemysław;Zhitkovich, A ...

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2019

Vitamin C increases DNA breaks and suppresses DNAdamage-independent activation of ATM by bleomycin.

Rubis, Blazej; Luczak,Michal W; Krawic,Casey; Zhitkovich,Anatoly

R01ES008786,R01ES028072


30926564

2019

WashU Epigenome Browser update 2019. Li, Daofeng; Hsu, Silas;Purushotham, Deepak;Sears, Renee L; Wang,Ting

U24ES026699 Nucleic Acids Res (201907 02)

31165883

2019

Widespread epigenetic changes to the enhancerlandscape of mouse liver induced by a specificxenobio ...

Rampersaud, Andy;Lodato, Nicholas J;Shin, Aram; Waxman,David J

R01ES024421 Toxicol Sci (2019 Jun 24) 31236583

2019

5-Formylcytosine mediated DNA-protein cross-linksblock DNA replication and induce mutations in huma...

Ji, Shaofei; Fu, Iwen;Naldiga, Spandana;Shao, Hongzhao; Basu,Ashis K; Broyde, Suse;Tretyak ...

R01ES023350,R01ES025987


29905846

2018

A DNA nick at Ku-blocked double-strand break endsserves as an entry site for exonuclease 1 (Exo1) o ...

Wang, Weibin; Daley,James M; Kwon,Youngho; Xue, Xiaoyu;Krasner, Danielle S;Miller, Adam S; ...

R01ES007061 J Biol Chem (2018 11 02) 30224356

2018

A high-fat diet alters genome-wide DNA methylationand gene expression in SM/J mice.

Keleher, MadelineRose; Zaidi, Rabab;Hicks, Lauren; Shah,Shyam; Xing, Xiaoyun;Li, Daofeng; ...

U24ES026699 BMC Genomics (2018 Dec07)

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2018

A new mitotic activity comes into focus. Saldivar, Joshua C;Cimprich, Karlene A

R01ES016486 Science (2018 01 05) 29302000

2018

A novel pooled-sample multiplex luminex assay forhigh-throughput measurement of relative telomere l ...

Jasmine, Farzana;Shinkle, Justin;Sabarinathan, Mekala;Ahsan, Habibul; Pierce,Brandon L; Kib ...

R35ES028379 Am J Hum Biol (2018 07) 29527774

2018

A quantitative PCR-based assay reveals thatnucleotide excision repair plays a predominant role in t...

Chesner, Lisa N;Campbell, Colin


29413806

2018

A study of telomere length, arsenic exposure, andarsenic toxicity in a Bangladeshi cohort.

Zhang, Chenan;Kibriya, Muhammad G;Jasmine, Farzana; Roy,Shantanu; Gao, Jianjun;Sabarinathan ...

P30ES027792,P42ES010349,R24ES028532,R35ES028379

Environ Res (2018 07) 29567420

2018

Accelerated DNA methylation age and the use ofantihypertensive medication among older adults.

Gao, Xu; Colicino,Elena; Shen, Jincheng;Just, Allan C;Nwanaji-Enwerem,Jamaji C; Wang, Cuic...

P30ES009089,P30ES023515,R01ES025225,R01ES027747


30414594

2018

Alterations in sperm DNA methylation, non-codingRNA and histone retention associate with DDT-induce...

Skinner, Michael K;Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;Nilsson, Eri ...

R01ES012974,R01ES012974


29482626

2018

Alterations in sperm DNA methylation, non-codingRNA expression, and histone retention mediate vincl ...

Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;McBirney, Margaux;Nilsson, Eric ...

R01ES012974,R01ES012974


29732173

2018

An intrinsic S/G2 checkpoint enforced by ATR. Saldivar, Joshua C;Hamperl, Stephan;Bocek, Michael J;Chung, Mingyu; Bass,Thomas E; Cisneros ...

R01ES016486 Science (2018 08 24) 30139873

2018

An oxidized abasic lesion inhibits base excision repairleading to DNA strand breaks in a trinucleot ...

Beaver, Jill M; Lai,Yanhao; Rolle, ShantellJ; Weng, Liwei;Greenberg, Marc M;Liu, Yuan

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2018

Animal models of endocrine disruption. Patisaul, Heather B;Fenton, Suzanne E;Aylor, David

P30ES025128,U01ES026717

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Arsenic exposure and risk of nonalcoholic fatty liverdisease (NAFLD) among U.S. adolescents and adu ...

Frediani, Jennifer K;Naioti, Eric A; Vos,Miriam B; Figueroa,Janet; Marsit, Carmen J;Welsh, ...

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Environ Health (2018 0115)

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Arsenic exposure during embryonic developmentalters the expression of the long noncoding RNAgrowth ...

Caldwell, Kevin K;Hafez, Alexander;Solomon, Elizabeth;Cunningham, Matthew;Allan, Andrea M

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Arsenic-Induced Carcinogenesis: The Impact ofmiRNA Dysregulation.

Cardoso, Ana PFerragut; Al-Eryani,Laila; States, JChristopher

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2018

Arsenite Targets the RING Finger Domain of Rbx1 E3Ubiquitin Ligase to Inhibit Proteasome-Mediated D ...

Jiang, Ji; Tam, LokMing; Wang,Pengcheng; Wang,Yinsheng


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Biochemical Studies and Molecular DynamicSimulations Reveal the Molecular Basis ofConformational C ...

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Caenorhabditis elegans as an emerging model systemin environmental epigenetics.

Weinhouse, Caren;Truong, Lisa; Meyer,Joel N; Allard, Patrick

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Characterization of a Mouse Model ofBörjeson-Forssman-Lehmann Syndrome.

Cheng, Cheng; Deng,Pan-Yue; Ikeuchi,Yoshiho; Yuede, Carla;Li, Daofeng; Rensing,Nicholas; H ...

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2018

Cisplatin-DNA adduct repair of transcribed genes iscontrolled by two circadian programs in mouse ti ...

Yang, Yanyan; Adebali,Ogun; Wu, Gang;Selby, Christopher P;Chiou, Yi-Ying;Rashid, Naim; Hu, ...

P30ES010126,R01ES027255


29735688

2018

Co-occurring expression and methylation QTLs allowdetection of common causal variants and shared bi ...

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P30ES027792,P42ES010349,R35ES028379

Nat Commun (2018 02 23) 29476079

2018

Cohort Profile: Pregnancy And Childhood Epigenetics(PACE) Consortium.

Felix, Janine F; Joubert,Bonnie R; Baccarelli,Andrea A; Sharp,Gemma C; Almqvist,Catarina; A ...

P01ES022832,P30ES007048,P30ES017885,P30ES025128,R00ES024116,R01ES025145,R01ES025145,R24ES028507

Int J Epidemiol (2018 0201)

29025028

2018

Comparative properties and functions of type 2 andtype 4 pigeon cryptochromes.

Wang, Xuefeng; Jing,Chengyu; Selby,Christopher P; Chiou,Yi-Ying; Yang,Yanyan; Wu, Wenjian;...

R01ES027255 Cell Mol Life Sci (2018Dec)

30264181

2018

Comprehensive Whole DNA Methylome Analysis byIntegrating MeDIP-seq and MRE-seq.

Xing, Xiaoyun; Zhang,Bo; Li, Daofeng; Wang,Ting

U24ES026699 Methods Mol Biol (2018) 29224147

2018

Computational prediction of CTCF/cohesin-basedintra-TAD loops that insulate chromatin contacts and...

Matthews, Bryan J;Waxman, David J

R01ES024421 Elife (2018 05 14) 29757144

2018

Configurational and Conformational Equilibria ofN6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3...

Bamberger, StephanieN; Malik, Chanchal K;Voehler, Markus W;Brown, Summer K;Pan, Hope; Johns ...

R01ES029357,T32ES007028


30169026

2018

Corrigendum: 5-Formylcytosine mediatedDNA-protein cross-links block DNA replication andinduce muta ...

Ji, Shaofei; Fu, Iwen;Naldiga, Spandana;Shao, Hongzhao; Basu,Ashis K; Broyde, Suse;Tretyak ...


30184121

2018

Crosstalk of Genetic Variants, Allele-Specific DNAMethylation, and Environmental Factors for Comple ...

Wang, Huishan; Lou,Dan; Wang, Zhibin

R01ES025761,R01ES025761,U01ES026721

Front Genet (2018) 30687383

2018

Cytotoxic and mutagenic properties of alkylphosphotriester lesions in Escherichia coli cells.

Wu, Jiabin; Wang,Pengcheng; Wang,Yinsheng


29514270

2018

Cytotoxic and mutagenic properties of minor-grooveO2-alkylthymidine lesions in human cells.

Wu, Jun; Wang,Pengcheng; Li, Lin;You, Changjun; Wang,Yinsheng

R01ES025121 J Biol Chem (2018 06 01) 29685891

2018

Cytotoxic and mutagenic properties ofO6-alkyl-2'-deoxyguanosine lesions in Escherichia colicells.

Wang, Pengcheng;Wang, Yinsheng

R01ES025121 J Biol Chem (2018 09 28) 30068548

2018

Determination of thiocyanate in exhaled breathcondensate.

Chandler, Joshua D;Horati, Hamed; Walker,Douglas I; Pagliano,Enea; Tirouvanziam,Rabindra; V ...

P30ES019776,R01ES023485,U2CES026560

Free Radic Biol Med (201810)

30144632

2018

Disulfiram combats cancer via cripplingvalosin-containing protein/p97 segregase adaptorNPL4.

Ding, Nan; Zhu,Qianzheng

R01ES012991 Transl Cancer Res (2018Apr)

30112292

2018

DNA Damage, Mutagenesis and Cancer. Basu, Ashis K R01ES023350 Int J Mol Sci (2018 Mar23)

29570697

2018

DNA polymerase beta participates in DNAEnd-joining.

Ray, Sreerupa; Breuer,Gregory; DeVeaux,Michelle; Zelterman,Daniel; Bindra, Ranjit;Sweasy, ...


29161447

2018

Early life Triclosan exposure and child adiposity at8 Years of age: a prospective cohort study.

Kalloo, Geetika;Calafat, Antonia M;Chen, Aimin; Yolton,Kimberly; Lanphear,Bruce P; Braun, ...

R01ES025214 Environ Health (2018 0305)

29506550

2018

Effect of frozen/thawed embryo transfer onbirthweight, macrosomia, and low birthweight ratesin US ...

Litzky, Julia F; Boulet,Sheree L; Esfandiari,Navid; Zhang, Yujia;Kissin, Dmitry M;Theiler, ...

P01ES022832,P30ES019776,R01ES025145,R01ES025145,R24ES028507

Am J Obstet Gynecol(2018 04)

29291410

2018

Effects of Cadmium Exposure on DNA Methylation atImprinting Control Regions and Genome-Wide inMoth ...

Cowley, Michael;Skaar, David A; Jima,Dereje D; Maguire,Rachel L; Hudson,Kathleen M; Park, ...

K22ES027510,P30ES025128

Environ Health Perspect(2018 03 08)

29529597

2018

Effects of Perinatal Exposure to Dibutyltin Chloride onFat and Glucose Metabolism in Mice, and Mole ...

Chamorro-García,Raquel; Shoucri,Bassem M; Willner,Sigal; Käch, Heidi;Janesick, Amanda;Blum ...

R01ES023316,R01ES023316


29787037

2018

Electron-Mediated Aminyl and Iminyl Radicals fromC5 Azido-Modified Pyrimidine Nucleosides AugmentR ...

Wen, Zhiwei; Peng,Jufang; Tuttle, PalomaR; Ren, Yaou; Garcia,Carol; Debnath, Dipra;Rishi, ...

R01ES005775,R01ES023569

Org Lett (2018 12 07) 30457873

2018

Endocrine disruptor exposure during developmentincreases incidence of uterine fibroids by altering ...

Prusinski Fernung,Lauren E; Yang, Qiwei;Sakamuro, Daitoku;Kumari, Alpana; Mas,Aymara; Al-He ...

R01ES028615 Biol Reprod (2018 10 01) 29688260

2018

Endocrine Disruptors and Developmental Origins ofNonalcoholic Fatty Liver Disease.

Treviño, Lindsey S;Katz, Tiffany A

U01ES026719 Endocrinology (2018 0101)

29126168

2018

Enhanced spontaneous DNA twisting/bendingfluctuations unveiled by fluorescence lifetimedistributio ...

Chakraborty, Sagnik;Steinbach, Peter J; Paul,Debamita; Mu, Hong;Broyde, Suse; Min,Jung-Hyu ...


29267981

2018

Environmentally Induced Epigenetic Plasticity inDevelopment: Epigenetic Toxicity and Epigenetic Ada...

Tian, Fu-Ying; Marsit,Carmen J


Curr Epidemiol Rep (2018Dec)

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2018

Environmentally induced epigenetic transgenerationalinheritance of disease.

Nilsson, Eric E;Sadler-Riggleman,Ingrid; Skinner,Michael K

R01ES012974,R01ES012974


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2018

Epigenetic mechanisms in the placenta related to infantneurodevelopment.

Lester, Barry M;Marsit, Carmen J

P01ES022832,R01ES025145,R01ES025145,R24ES028507

Epigenomics (2018 03 01) 29381081

2018

Epigenetic Transgenerational Inheritance of AlteredSperm Histone Retention Sites.

Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;Skinner, Michael K

R01ES012974,R01ES012974

Sci Rep (2018 03 28) 29593303

2018

Evidence that microplastics aggravate the toxicity oforganophosphorus flame retardants in mice (Mus ...

Deng, Yongfeng;Zhang, Yan; Qiao,Ruxia; Bonilla, MelvinM; Yang, Xiaoliang;Ren, Hongqiang; L ...

R01ES027981 J Hazard Mater (2018 0905)

29908513

2018

Expanding upon the Human Myometrial Stem CellHypothesis and the Role of Race, Hormones, Age, andPa ...

Prusinski Fernung,Lauren E; Jones,Kimya; Mas, Aymara;Kleven, Daniel; Waller,Jennifer L; Al- ...

R01ES028615 Am J Pathol (2018 10) 30075150

2018

Explosive mutation accumulation triggered byheterozygous human Pol ε proofreading-deficiency isdri ...

Hodel, Karl P; de Borja,Richard; Henninger,Erin E; Campbell,Brittany B; Ungerleider,Nathan; ...

R01ES028271 Elife (2018 02 28) 29488881

2018

Extracellular vesicle-enriched microRNAs interact inthe association between long-term particulate m ...

Rodosthenous,Rodosthenis S; Kloog,Itai; Colicino, Elena;Zhong, Jia; Herrera,Luis A; Vokonas ...

P30ES009089,P30ES023515,R01ES027747

Environ Res (2018 11) 30216846

2018

Functional Analysis of Cancer-Associated DNAPolymerase ε Variants in Saccharomyces cerevisiae.

Barbari, Stephanie R;Kane, Daniel P; Moore,Elizabeth A;Shcherbakova, Polina V

R01ES015869 G3 (Bethesda) (2018 0302)

29352080

2018

Genetic control of predominantly error-free replicationthrough an acrolein-derived minor-groove DNA ...

Yoon, Jung-Hoon;Hodge, Richard P;Hackfeld, Linda C;Park, Jeseong; RoyChoudhury, Jayati; Pra...

R01ES022948 J Biol Chem (2018 02 23) 29330301

2018

Genome-wide association study identifies a novellocus for cannabis dependence.

Agrawal, A; Chou, Y-L;Carey, C E; Baranger, DA A; Zhang, B; Sherva,R; Wetherill, L; Kapoor...

U24ES026699 Mol Psychiatry (2018 05) 29112194

2018

Genome-wide association study of telomere lengthamong South Asians identifies a second RTEL1 associ...

Delgado, Dayana A;Zhang, Chenan; Chen,Lin S; Gao, Jianjun;Roy, Shantanu; Shinkle,Justin; S ...

P30ES027792,P42ES010349,R35ES028379

J Med Genet (2018 01) 29151059

2018

Genome-wide DNA methylation profiling of primarycolorectal laterally spreading tumors identifies di ...

Zhu, Liangliang; Yan,Feihu; Wang, Zhen;Dong, Haiyan; Bian,Chengling; Wang, Ting;Yu, Enda; ...

U24ES026699 Int J Cancer (2018 11 15) 30183087

2018

Genome-wide excision repair in Arabidopsis iscoupled to transcription and reflects circadian gene e ...

Oztas, Onur; Selby,Christopher P; Sancar,Aziz; Adebali, Ogun

P30ES010126,R01ES027255

Nat Commun (2018 04 17) 29666379

2018

High-throughput inference of pairwise coalescencetimes identifies signals of selection and enriched ...

Palamara, PierFrancesco; Terhorst,Jonathan; Song, Yun S;Price, Alkes L

R03ES027902 Nat Genet (2018 09) 30104759

2018

Histone Modifications: Epigenetic Mediators ofEnvironmental Exposure Memory.

Camacho, Jessica;Allard, Patrick

R01ES027487,R01ES027487

Epigenet Insights (2018) 30443644

2018

Histone tails decrease N7-methyl-2'-deoxyguanosinedepurination and yield DNA-protein cross-links in ...

Yang, Kun; Park,Daeyoon; Tretyakova,Natalia Y; Greenberg,Marc M


30429328

2018

Hypoxia Promotes Resistance to EGFR Inhibition inNSCLC Cells via the Histone Demethylases, LSD1and ...

Lu, Yuhong; Liu,Yanfeng; Oeck,Sebastian; Glazer, PeterM

R01ES005775 Mol Cancer Res (2018 10) 29934325

2018

Identification of ATIC as a Novel Target forChemoradiosensitization.

Liu, Xiangfei; Paila,Uma Devi; Teraoka,Sharon N; Wright,Jocyndra A; Huang,Xin; Quinlan, Aa ...

R01ES027121 Int J Radiat Oncol BiolPhys (2018 01 01)

29029884

2018

Identification of YTH Domain-Containing Proteins asthe Readers for N1-Methyladenosine in RNA.

Dai, Xiaoxia; Wang,Tianlu; Gonzalez,Gwendolyn; Wang,Yinsheng

R01ES025121,T32ES018827

Anal Chem (2018 06 05) 29791134

2018

Impact of CAR Agonist Ligand TCPOBOP on MouseLiver Chromatin Accessibility.

Lodato, Nicholas J;Rampersaud, Andy;Waxman, David J

R01ES024421 Toxicol Sci (2018 07 01) 29617930

2018

Impact of Early-Life Weight Status on CognitiveAbilities in Children.

Li, Nan; Yolton,Kimberly; Lanphear,Bruce P; Chen, Aimin;Kalkwarf, Heidi J;Braun, Joseph M

R01ES025214 Obesity (Silver Spring)(2018 06)

29797555

2018

Impact of prenatal arsenic exposure on chronic adultdiseases.

Young, Jamie L; Cai,Lu; States, JChristopher

R01ES027778,T32ES011564

Syst Biol Reprod Med(2018 Dec)

29873257

2018

Impact of tobacco-specific nitrosamine-derived DNAadducts on the efficiency and fidelity of DNA rep ...

Du, Hua; Leng, Jiapeng;Wang, Pengcheng; Li,Lin; Wang, Yinsheng

R01ES025121 J Biol Chem (2018 07 13) 29789427

2018

Importance of homo-dimerization ofFanconi-associated nuclease 1 in DNA flap cleavage.

Rao, Timsi; Longerich,Simonne; Zhao,Weixing; Aihara,Hideki; Sung, Patrick;Xiong, Yong


29518739

2018

In a Class of Its Own: A New Family ofDeubiquitinases Promotes Genome Stability.

Coleman, Kate E;Huang, Tony T

R01ES025166 Mol Cell (2018 04 05) 29625031

2018

Incomplete base excision repair contributes to celldeath from antibiotics and other stresses.

Gruber, Charley C;Walker, Graham C


30181041

2018

Inhalational exposure to particulate matter air pollutionalters the composition of the gut microbio ...

Mutlu, Ece A; Comba,Işın Y; Cho, Takugo;Engen, Phillip A;Yazıcı, Cemal;Soberanes, Saul; Ha ...

R01ES015024,U01ES026718

Environ Pollut (2018 Sep) 29783199

2018

Insights into the effect of minor groove interactionsand metal cofactors on mutagenic replication b ...

Koag, Myong-Chul;Lee, Seongmin

R01ES026676 Biochem J (2018 02 09) 29301983

2018

Integrating -Omics Approaches into HumanPopulation-Based Studies of Prenatal and Early-LifeExposur ...

Everson, Todd M;Marsit, Carmen J



30054820

2018

Intrauterine multi-metal exposure is associated withreduced fetal growth through modulation of the ...

Deyssenroth, Maya A;Gennings, Chris; Liu,Shelley H; Peng,Shouneng; Hao, Ke;Lambertini, Luc ...

P01ES022832,P30ES023515,P42ES007373,R01ES025145,R01ES025145,R24ES028507

Environ Int (2018 11) 30125854

2018

Introduction to the Thematic Minireview Series: DNAdouble-strand break repair and pathway choice.

Sung, Patrick R01ES007061 J Biol Chem (2018 07 06) 29853635

2018

Krebs-cycle-deficient hereditary cancer syndromes aredefined by defects in homologous-recombination ...

Sulkowski, Parker L;Sundaram, Ranjini K;Oeck, Sebastian; Corso,Christopher D; Liu,Yanfeng; ...

R01ES005775 Nat Genet (2018 08) 30013182

2018

Lesion Sensing during Initial Binding by YeastXPC/Rad4: Toward Predicting Resistance toNucleotide ...

Mu, Hong; Zhang,Yingkai; Geacintov,Nicholas E; Broyde,Suse


30284444

2018

Long repeating (TTAGGG) n single-stranded DNAself-condenses i ...

Kar, Anirban; Jones,Nathan; Arat, N Özlem;Fishel, Richard;Griffith, Jack D

R56ES013773 J Biol Chem (2018 06 15) 29674319

2018

Long-Term In Vitro Expansion of Epithelial StemCells Enabled by Pharmacological Inhibition ofPAK1- ...

Zhang, Chengkang;Lee, Hyung Joo;Shrivastava, Anura;Wang, Ruipeng;McQuiston, Travis J;Chall ...

U24ES026699 Cell Rep (2018 10 16) 30332641

2018

Loss of E2F7 confers resistance to poly-ADP-ribosepolymerase (PARP) inhibitors in BRCA2-deficient c...

Clements, Kristen E;Thakar, Tanay; Nicolae,Claudia M; Liang,Xinwen; Wang,Hong-Gang; Moldova...


30032296

2018

Mapping-free variant calling using haplotypereconstruction from k-mer frequencies.

Audano, Peter A;Ravishankar,Shashidhar; Vannberg,Fredrik O

R01ES026243 Bioinformatics (2018 0515)

29186321

2018

Meiosis-specific recombinase Dmc1 is a potentinhibitor of the Srs2 antirecombinase.

Crickard, J Brooks;Kaniecki, Kyle; Kwon,Youngho; Sung,Patrick; Greene, Eric C


30301803

2018

miRNA expression profiles of premalignant andmalignant arsenic-induced skin lesions.

Al-Eryani, Laila;Jenkins, Samantha F;States, Vanessa A; Pan,Jianmin; Malone, JanineC; Rai, ...

R01ES027778,T35ES014559

PLoS One (2018) 30114287

2018

Mitochondrial network responses in oxidativephysiology and disease.

Go, Young-Mi;Fernandes, Jolyn; Hu,Xin; Uppal, Karan;Jones, Dean P

P30ES019776,R01ES023485


29317273

2018

Modification of Wnt signaling pathway onparaquat-induced inhibition of neural progenitor cellproli ...

Zhao, Lina; Yan,Mengling; Wang,Xinjin; Xiong, Guiya;Wu, Chunhua; Wang,Zhibin; Zhou, Zhiju ...

R01ES025761,R01ES025761,U01ES026721

Food Chem Toxicol (2018Nov)

30171970

2018

Molecular basis for damage recognition andverification by XPC-RAD23B and TFIIH in nucleotideexcisi ...

Mu, Hong; Geacintov,Nicholas E; Broyde,Suse; Yeo, Jung-Eun;Schärer, Orlando D


30174301

2018

Monoubiquitinated γ-H2AX: Abundant product andspecific biomarker for non-apoptotic DNAdouble-stran ...

Luczak, Michal W;Zhitkovich, Anatoly

R01ES008786,R01ES028072


30006243

2018

Mutant FUS causes DNA ligation defects to inhibitoxidative damage repair in Amyotrophic Lateral Scl ...

Wang, Haibo; Guo,Wenting; Mitra, Joy;Hegde, Pavana M;Vandoorne, Tijs;Eckelmann, Bradley J;...

R01ES012512 Nat Commun (2018 09 11) 30206235

2018

Mutation of hop-1 and pink-1 attenuates vulnerabilityof neurotoxicity in C. elegans: the role of mi ...

Wu, Siyu; Lei, Lili;Song, Yang; Liu,Mengting; Lu, Shibo;Lou, Dan; Shi,Yonghong; Wang, Zh ...

R01ES025761,R01ES025761,U01ES026721

Exp Neurol (2018 11) 30076829

2018

Myeloperoxidase oxidation of methionine associateswith early cystic fibrosis lung disease.

Chandler, Joshua D;Margaroli, Camilla;Horati, Hamed; Kilgore,Matthew B; Veltman,Mieke; Liu, ...

P30ES019776,R01ES023485

Eur Respir J (2018 10) 30190273

2018

Nickel exposure induces persistent mesenchymalphenotype in human lung epithelial cells through epig...

Jose, Cynthia C;Jagannathan,Lakshmanan; Tanwar,Vinay S; Zhang,Xiaoru; Zang,Chongzhi; Cudda ...

P30ES000260,R01ES024727

Mol Carcinog (2018 06) 29528143

2018

Normalized Retention Time for Targeted Analysis ofthe DNA Adductome.

Cui, Yuxiang; Wang,Pengcheng; Yu, Yang;Yuan, Jun; Wang,Yinsheng

R01ES029749 Anal Chem (2018 12 18) 30500177

2018

Not just heads and tails: The complexity of the spermepigenome.

Gold, Hannah B; Jung,Yoon Hee; Corces,Victor G

R01ES027859,R01ES027859

J Biol Chem (2018 09 07) 29507096

2018

Nucleosome positions establish an extended mutationsignature in melanoma.

Brown, Alexander J;Mao, Peng; Smerdon,Michael J; Wyrick, JohnJ; Roberts, Steven A

R01ES028698 PLoS Genet (2018 11) 30485262

2018

Oxidative stress predicts cognitive decline with agingin healthy adults: an observational study.

Hajjar, Ihab; Hayek,Salim S; Goldstein,Felicia C; Martin, Greg;Jones, Dean P;Quyyumi, Arsh ...

P30ES019776,R01ES023485

J Neuroinflammation(2018 Jan 16)

29338747

2018

PARP10 promotes cellular proliferation andtumorigenesis by alleviating replication stress.

Schleicher, Emily M;Galvan, Adri M;Imamura-Kawasawa,Yuka; Moldovan,George-Lucian;Nicolae, ...


30032250

2018

Particulate Matter Air Pollution: Effects on theCardiovascular System.

Hamanaka, Robert B;Mutlu, Gökhan M

P30ES027792,R01ES015024,U01ES026718

Front Endocrinol(Lausanne) (2018)

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2018

Patterns of early life body mass index and childhoodoverweight and obesity status at eight years of ...

Braun, Joseph M;Kalkwarf, Heidi J;Papandonatos, GeorgeD; Chen, Aimin;Lanphear, Bruce P

R01ES025214 BMC Pediatr (2018 05 11) 29751833

2018

Permissiveness to form pluripotent stem cells may bean evolutionarily derived characteristic in Mus ...

Garbutt, Tiffany A;Konneker, Thomas I;Konganti, Kranti;Hillhouse, Andrew E;Swift-Haire, Fra ...

P42ES027704,U01ES026717

Sci Rep (2018 10 02) 30279419

2018

Population-based dose-response analysis of livertranscriptional response to trichloroethylene in mo ...

Venkatratnam,Abhishek; House, JohnS; Konganti, Kranti;McKenney, Connor;Threadgill, David W; ...

P30ES025128,P42ES027704,U01ES026717

Mamm Genome (2018Feb)

29353386

2018

Preconception cold-induced epigenetic inheritance. Skinner, Michael K R01ES012974,R01ES012974

Nat Med (2018 09) 30194411

2018

Prenatal Exposure to Bisphenol A Disrupts NaturallyOccurring Bimodal DNA Methylation at Proximal Pr...

Taylor, Julia A; Shioda,Keiko; Mitsunaga,Shino; Yawata, Shiomi;Angle, Brittany M;Nagel, Su ...

R01ES023316,R01ES023316


29220483

2018

Prenatal exposure to perfluoroalkyl substances andadipocytokines: the HOME Study.

Buck, Catherine O;Eliot, Melissa N;Kelsey, Karl T; Calafat,Antonia M; Chen,Aimin; Ehrlich, ...

R01ES025214 Pediatr Res (2018 12) 30250302

2018

Prenatal Exposure to Perfluoroalkyl Substances: InfantBirth Weight and Early Life Growth.

Shoaff, Jessica;Papandonatos, GeorgeD; Calafat, Antonia M;Chen, Aimin; Lanphear,Bruce P; Eh ...

R01ES025214 Environ Epidemiol (2018Jun)

30272047

2018

Prenatal influences on temperament development: Therole of environmental epigenetics.

Gartstein, Maria A;Skinner, Michael K

R01ES012974,R01ES012974

Dev Psychopathol (201810)

29229018

2018

PTEN Regulates Nonhomologous End Joining ByEpigenetic Induction of NHEJ1/XLF.

Sulkowski, Parker L;Scanlon, Susan E; Oeck,Sebastian; Glazer, PeterM


2018

Putrescine as indicator of manganese neurotoxicity:Dose-response study in human SH-SY5Y cells.

Fernandes, Jolyn;Chandler, Joshua D;Liu, Ken H; Uppal,Karan; Go, Young-Mi;Jones, Dean P

P30ES019776,R01ES023485

Food Chem Toxicol (2018Jun)

29684492

2018

Pyrimidine Nucleosides with a Reactive(β-Chlorovinyl)sulfone or (β-Keto)sulfone Group atthe C5 Pos ...

Suzol, Sazzad H;Howlader, A Hasan;Wen, Zhiwei; Ren,Yaou; Laverde,Eduardo E; Garcia,Carol; ...

R01ES023569 ACS Omega (2018 Apr 30) 29732453

2018

Rapid onset of multiple concurrent squamous cellcarcinomas associated with the use of an arsenic-co ...

Siefring, Mark Louis;Lu, Doanh; States, JChristopher; VanHoang, Minh

R01ES027778 BMJ Case Rep (2018 Mar30)

29602886

2018

RE: "INVITED COMMENTARY: EXPOSUREBIOMARKERS INDICATE MORE THAN JUSTEXPOSURE".

Braun, Joseph M R01ES025214 Am J Epidemiol (2018 0401)

29351641

2018

Redox Equivalents and Mitochondrial Bioenergetics. Roede, James R; Go,Young-Mi; Jones, DeanP

R01ES023485,T32ES012870


2018

Regulation of Hed1 and Rad54 binding duringmaturation of the meiosis-specific presynapticcomplex.

Crickard, J Brooks;Kaniecki, Kyle; Kwon,YoungHo; Sung,Patrick; Lisby, Michael;Greene, Eric ...

R01ES007061 EMBO J (2018 04 03) 29444896

2018

Reorientation of the Methyl Group in MAs(III) is theRate-Limiting Step in the ArsM As(III) S-Adenos ...

Packianathan, Charles;Li, Jiaojiao; Kandavelu,Palani; Sankaran,Banumathi; Rosen,Barry P

R01ES023779 ACS Omega (2018 Mar) 29600290

2018

Repair of DNA double-strand breaks by mammalianalternative end-joining pathways.

Sallmyr, Annahita;Tomkinson, Alan E

R01ES012512 J Biol Chem (2018 07 06) 29530982

2018

Retinoid X Receptor Activation During Adipogenesisof Female Mesenchymal Stem Cells Programs a Dysfu...

Shoucri, Bassem M;Hung, Victor T;Chamorro-García,Raquel; Shioda, Toshi;Blumberg, Bruce

R01ES023316,R01ES023316


29860300

2018

Rev7 dimerization is important for assembly andfunction of the Rev1/Polζ translesion synthesis comp ...

Rizzo, Alessandro A;Vassel, Faye-Marie;Chatterjee, Nimrat;D'Souza, Sanjay; Li,Yunfeng; Hao, ...

P30ES002109,R35ES028303


30111544

2018

RNA polymerase II is released from the DNA templateduring transcription-coupled repair in mammalian ...

Chiou, Yi-Ying; Hu,Jinchuan; Sancar, Aziz;Selby, Christopher P

R01ES027255 J Biol Chem (2018 02 16) 29282293

2018

Roadmap for investigating epigenome deregulationand environmental origins of cancer.

Herceg, Zdenko;Ghantous, Akram;Wild, Christopher P;Sklias, Athena; Casati,Lavinia; Duthie, ...

P30ES010126,R01ES025145,R01ES025145,R24ES028507

Int J Cancer (2018 03 01) 28836271

2018

Role of DNA methylation in altered gene expressionpatterns in adult zebrafish (Danio rerio) exposed ...

Aluru, Neelakanteswar;Karchner, Sibel I;Krick, Keegan S; Zhu,Wei; Liu, Jiang

R01ES024915,R01ES024915

Environ Epigenet (2018Jan)

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2018

S-Nitrosoglutathione Reductase Is Essential forProtecting the Female Heart FromIschemia-Reperfusio ...

Casin, Kevin M;Fallica, Jonathan;Mackowski, Nathan;Veenema, Ryne J; Chan,Ashley; St Paul, ...

T32ES007141,U01ES026721

Circ Res (2018 11 09) 30571462

2018

Screening for gene-environment (G×E) interactionusing omics data from exposed individuals: an appli ...

Argos, Maria; Tong,Lin; Roy, Shantanu;Sabarinathan, Mekala;Ahmed, Alauddin;Islam, Md Tariq ...

P30ES009089,P30ES027792,P42ES010349,R35ES028379

Mamm Genome (2018 02) 29453499

2018

Selective inhibition of CTCF binding by iAs directsTET-mediated reprogramming of 5-hydroxymethylati...

Rea, Matthew;Gripshover, Tyler;Fondufe-Mittendorf,Yvonne

R01ES024478,R25ES027684


29175454

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Selenium at the redox interface of the genome,metabolome and exposome.

Fernandes, Jolyn; Hu,Xin; Ryan Smith, M;Go, Young-Mi; Jones,Dean P

R01ES023485 Free Radic Biol Med (201811 01)

29883789

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Selenium Supplementation Alters Hepatic Energy andFatty Acid Metabolism in Mice.

Hu, Xin; Chandler,Joshua D; Orr, MichaelL; Hao, Li; Liu, Ken;Uppal, Karan; Go,Young-Mi; J ...

P30ES019776,R01ES023485

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Selenium supplementation prevents metabolic andtranscriptomic responses to cadmium in mouse lung.

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Sex-Dependent Effects of the Histone DeacetylaseInhibitor, Sodium Valproate, on Reversal Learning A...

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2018

Single-nucleotide resolution dynamic repair maps ofUV damage in Saccharomyces cerevisiae genome.

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Site-specific cross-linking of proteins to DNA via anew bioorthogonal approach employing oxime liga ...

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Smoking gun for a rare mutation mechanism. Goodman, Myron F R35ES028343 Nature (2018 02 08) 29420502

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Soluble inflammatory mediators induce transcriptionalre-organization that is independent of dna met ...

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Spontaneous self-segregation of Rad51 and Dmc1DNA recombinases within mixed recombinasefilaments.

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2018

Stochastic Endogenous Replication Stress CausesATR-Triggered Fluctuations in CDK2 Activity thatDyn ...

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2018

Structural and Kinetic Studies of the Effect of GuanineN7 Alkylation and Metal Cofactors on DNA Rep ...

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Successes and failures of uterine leiomyoma drugdiscovery.

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Suppression of homology-dependent DNAdouble-strand break repair induces PARP inhibitorsensitivity ...

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2018

Synergistic effects of H3 and H4 nucleosome tails onstructure and dynamics of a lesion-containing D ...

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Technical adequacy of bisulfite sequencing andpyrosequencing for detection of mitochondrial DNAmet ...

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PLoS One (2018) 29420656

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The 3D Genome Browser: a web-based browser forvisualizing 3D genome organization and long-rangechr ...

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U24ES026699 Genome Biol (2018 10 04) 30286773

2018

The association of traffic-related air and noisepollution with maternal blood pressure and hyperten ...

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The COP9 signalosome inhibits Cullin-RING E3ubiquitin ligases independently of its deneddylase acti...

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The deoxyribose phosphate lyase of DNA polymeraseβ suppresses a processive DNA synthesis to prevent ...

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The Emerging Role of p27 in Development ofDiseases.

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The emerging spectrum of early life exposure-relatedinflammation and epigenetic therapy.

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The hypoxic tumor microenvironment in vivo selectsthe cancer stem cell fate of breast cancer cells.

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The Memory of Environmental Chemical Exposure inC. elegans Is Dependent on the Jumonji Demethylases...

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Cell Rep (2018 05 22) 29791850

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The NIEHS TaRGET II Consortium andenvironmental epigenomics.

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The ontogeny of myometrial stem cells in OCT4-GFPtransgenic mouse model.

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The Structure of an As(III) S-AdenosylmethionineMethyltransferase with 3-Coordinately Bound As(III)...

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Thiolation in arsenic metabolism: a chemicalperspective.

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Toxicological Antagonism among Welding FumeMetals: Inactivation of Soluble Cr(VI) by Iron.

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Translesion polymerase kappa-dependent DNAsynthesis underlies replication fork recovery.

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Transposable Element Mediated Innovation in GeneRegulatory Landscapes of Cells: Re-Visiting the "Ge ...

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2018

Upregulation of histone-lysine methyltransferasesplays a causal role in hexavalent chromium-induced ...

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Variability and predictors of serum perfluoroalkylsubstance concentrations during pregnancy and ear ...

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R01ES025214 Environ Res (2018 08) 29734025

2018

What is the potential of nanolock- andnanocross-nanopore technology in cancer diagnosis?

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xMWAS: a data-driven integration and differentialnetwork analysis tool.

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2-Hydroxyglutarate produced by neomorphic IDHmutations suppresses homologous recombination andindu ...

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A comparison of nucleosome organization inDrosophila cell lines.

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A METHYLATION-TO-EXPRESSION FEATUREMODEL FOR GENERATING ACCURATEPROGNOSTIC RISK SCORES AND IDENTIF ...

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A novel role of the Dna2 translocase function in DNAbreak resection.

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2017

A parametric model to estimate the proportion fromtrue null using a distribution for p-values.

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A role for the base excision repair enzyme NEIL3 inreplication-dependent repair of interstrand DNA ...

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Abasic and oxidized ribonucleotides embedded inDNA are processed by human APE1 and not by RNaseH2.

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Acetylation Enhances TET2 Function in Protectingagainst Abnormal DNA Methylation during OxidativeS ...

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Airborne Particulate Matter Induces NonallergicEosinophilic Sinonasal Inflammation in Mice.

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Ancestral perinatal obesogen exposure results in atransgenerational thrifty phenotype in mice.

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Anti-tumor Activity of miniPEG-γ-Modified PNAs toInhibit MicroRNA-210 for Cancer Therapy.

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ATM, radiation, and the risk of second primary breastcancer.

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2017

Atrazine induced epigenetic transgenerationalinheritance of disease, lean phenotype and spermepimu ...

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PLoS One (2017) 28931070

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Bacterial resistance to arsenic protects against protistkilling.

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R01ES023779 Biometals (2017 04) 28210928

2017

Bisphenol A in eggs causes development-specific livermolecular reprogramming in two generations of ...

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BRCA1-BARD1 promotes RAD51-mediatedhomologous DNA pairing.

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2017

Brevetoxin-2, is a unique inhibitor of the C-terminalredox center of mammalian thioredoxin reductas ...

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Cadmium stimulates myofibroblast differentiation andmouse lung fibrosis.

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R01ES023485 Toxicology (2017 05 15) 28341147

2017

Cellular Repair of DNA-DNA Cross-Links Induced by1,2,3,4-Diepoxybutane.

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CHD4 Has Oncogenic Functions in Initiating andMaintaining Epigenetic Suppression of MultipleTumor ...

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2017

Chemical Biology of N5-SubstitutedFormamidopyrimidine DNA Adducts.

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Chronic Cigarette Smoke-Induced EpigenomicChanges Precede Sensitization of Bronchial EpithelialCel ...

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2017

Comprehensive Analysis of Hypermutation in HumanCancer.

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2017

Controlling the Graphene-Bio Interface: Dispersions inAnimal Sera for Enhanced Stability and Reduce ...

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2017

Copper-mediated DNA damage by theneurotransmitter dopamine and L-DOPA: Apro-oxidant mechanism.

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Correction to: Parma consensus statement onmetabolic disruptors.

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Critical threshold levels of DNA methyltransferase 1are required to maintain DNA methylation across ...

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2017

Cryo-EM structures of human RAD51 recombinasefilaments during catalysis of DNA-strand exchange.

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Cytotoxic and Mutagenic Properties of C3'-EpimericLesions of 2'-Deoxyribonucleosides in Escherichia ...

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R01ES025121,T32ES018827

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2017

Detection of the Excised, Damage-containingOligonucleotide Products of Nucleotide ExcisionRepair i ...

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Differential DNA Methylation Regions in AdultHuman Sperm following Adolescent Chemotherapy:Potenti ...

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PLoS One (2017) 28146567

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Dissociation of Rad51 Presynaptic Complexes andHeteroduplex DNA Joints by Tandem Assemblies ofSrs2 ...

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2017

DNA methyltransferase 3b regulates articular cartilagehomeostasis by altering metabolism.

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2017

DNA Polymerase Beta Germline Variant ConfersCellular Response to Cisplatin Therapy.

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2017

DNA repair and systemic lupus erythematosus. Meas, Rithy; Burak,Matthew J; Sweasy,Joann B


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DNMT and HDAC inhibitors induce cryptictranscription start sites encoded in long terminalrepeats.

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2017

Dynamic maps of UV damage formation and repair forthe human genome.

Hu, Jinchuan; Adebali,Ogun; Adar, Sheera;Sancar, Aziz

P30ES010126,R01ES027255


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Dynamics of p53: A Master Decider of Cell Fate. Luo, Qingyin; Beaver,Jill M; Liu, Yuan;Zhang, Zunzhen

R01ES023569 Genes (Basel) (2017 Feb09)

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Early Life Exposure to Low Levels of AHR AgonistPCB126 (3,3',4,4',5-Pentachlorobiphenyl) Reprograms...

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Early-life exposure to EDCs: role in childhood obesityand neurodevelopment.

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Early-Life Phthalate Exposure and Adiposity at 8Years of Age.

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Endocrine Disruptors and Health Effects in Africa: ACall for Action.

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Endocrine-disrupting chemicals and fatty liver disease.

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Enhancement of BLM-DNA2-Mediated Long-RangeDNA End Resection by CtIP.

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EpiCompare: an online tool to define and exploregenomic regions with tissue or cell type-specific e ...

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Epigenetic effects of environmental chemicals:insights from zebrafish.

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Epigenetic variation between urban and ruralpopulations of Darwin's finches.

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Epigenetics and adaptive phenotypic variation betweenhabitats in an asexual snail.

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Sci Rep (2017 10 26) 29074962

2017

Epigenomic annotation of noncoding mutationsidentifies mutated pathways in primary liver cancer.

Lowdon, Rebecca F;Wang, Ting

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Epigenomic reprogramming in inorganicarsenic-mediated gene expression patterns duringcarcinogenesi ...

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ETV2/ER71 regulates hematopoietic regeneration bypromoting hematopoietic stem cell proliferation.

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2017

Expression quantitative trait loci (eQTLs) in humanplacentas suggest developmental origins of compl ...

Peng, Shouneng;Deyssenroth, Maya A;Di Narzo, Antonio F;Lambertini, Luca;Marsit, Carmen J; C ...

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Fathers Matter: Why It's Time to Consider the Impactof Paternal Environmental Exposures on Children ...

Braun, Joseph M;Messerlian, Carmen;Hauser, Russ

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Forging Ahead through Darkness: PCNA, Still thePrincipal Conductor at the Replication Fork.

Choe, Katherine N;Moldovan,George-Lucian

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From the Cover: Manganese Stimulates MitochondrialH2O2 Production in SH-SY5Y Human NeuroblastomaCe ...

Fernandes, Jolyn; Hao,Li; Bijli, Kaiser M;Chandler, Joshua D;Orr, Michael; Hu, Xin;Jones, ...

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Toxicol Sci (2017 01) 27701121

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Functional cis-regulatory modules encoded bymouse-specific endogenous retrovirus.

Sundaram, Vasavi;Choudhary, Mayank NK; Pehrsson, Erica;Xing, Xiaoyun; Fiore,Christopher; Pa ...

U24ES026699 Nat Commun (2017 03 28) 28348391

2017

Generational comparisons (F1 versus F3) ofvinclozolin induced epigenetic transgenerationalinherita ...

Beck, Daniel;Sadler-Riggleman,Ingrid; Skinner,Michael K

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Genome-wide DNA methylation reprogramming inresponse to inorganic arsenic links inhibition of CTCF...

Rea, Matthew; Eckstein,Meredith; Eleazer,Rebekah; Smith,Caroline;Fondufe-Mittendorf,Yvonne ...

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2017

Genome-wide transcription-coupled repair inEscherichia coli is mediated by the Mfd translocase.

Adebali, Ogun; Chiou,Yi-Ying; Hu, Jinchuan;Sancar, Aziz; Selby,Christopher P


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Gestational exposure to endocrine disruptingchemicals in relation to infant birth weight: a Bayesia...

Woods, Meghan M;Lanphear, Bruce P;Braun, Joseph M;McCandless, LawrenceC

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Human CRL4DDB2 ubiquitin ligase preferentiallyregulates post-repair chromatin restoration of H3K56A...

Zhu, Qianzheng; Wei,Shengcai; Sharma,Nidhi; Wani, Gulzar;He, Jinshan; Wani,Altaf A

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2017

Human DNA polymerase η accommodates RNA forstrand extension.

Su, Yan; Egli, Martin;Guengerich, F Peter

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J Biol Chem (2017 11 03) 28972162

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Human genome-wide repair map of DNA damagecaused by the cigarette smoke carcinogenbenzo[a]pyrene.

Li, Wentao; Hu,Jinchuan; Adebali,Ogun; Adar, Sheera;Yang, Yanyan; Chiou,Yi-Ying; Sancar, ...

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Human RAD52 interactions with replication protein Aand the RAD51 presynaptic complex.

Ma, Chu Jian; Kwon,Youngho; Sung,Patrick; Greene, Eric C

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Identification of a unique gene expression signature inmercury and 2,3,7,8-tetrachlorodibenzo-p-dio ...

Jagannathan,Lakshmanan; Jose,Cynthia C; Tanwar,Vinay Singh;Bhattacharya, Sudin;Cuddapah, S ...

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Identification of critical base pairs required for CTCFbinding in motif M1 and M2.

Li, Wufeng; Shang,Liping; Huang,Kaimeng; Li, Jiao;Wang, Zhibin; Yao,Hongjie

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Incorporation of Biological Knowledge Into the Studyof Gene-Environment Interactions.

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Interstrand cross-links arising from strand breaks attrue abasic sites in duplex DNA.

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Is it time to reassess current safety standards forglyphosate-based herbicides?

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Lessons Learned From Past Gene-EnvironmentInteraction Successes.

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2017

Linking Genes to Microbial Biogeochemical Cycling:Lessons from Arsenic.

Zhu, Yong-Guan; Xue,Xi-Mei; Kappler,Andreas; Rosen, BarryP; Meharg, Andrew A

R01ES023779 Environ Sci Technol (2017Jul 05)

28602082

2017

Liquid Chromatography-Tandem Mass Spectrometryfor the Quantification of Tobacco-Specific Nitrosamin...

Leng, Jiapeng; Wang,Yinsheng

R01ES025121 Anal Chem (2017 09 05) 28749651

2017

Machine learning for epigenetics and future medicalapplications.

Holder, Lawrence B;Haque, M Muksitul;Skinner, Michael K

R01ES012974,R01ES012974

Epigenetics (2017 07 03) 28524769

2017

Mass Spectrometry Based Proteomics Study ofCisplatin-Induced DNA-Protein Cross-Linking inHuman Fib ...

Ming, Xun; Groehler4th, Arnold;Michaelson-Richie,Erin D; Villalta, PeterW; Campbell, Colin; ...


28282121

2017

Mass Spectrometry-Based Tools to CharacterizeDNA-Protein Cross-Linking by Bis-Electrophiles.

Groehler 4th, Arnold;Degner, Amanda;Tretyakova, Natalia Y

R01ES023350 Basic Clin PharmacolToxicol (2017 Sep)

28032943

2017

Maternal serum PFOA concentration and DNAmethylation in cord blood: A pilot study.

Kingsley, Samantha L;Kelsey, Karl T; Butler,Rondi; Chen, Aimin;Eliot, Melissa N;Romano, Me ...

R01ES025214 Environ Res (2017 10) 28645023

2017

Mechanism of DNA alkylation-induced transcriptionalstalling, lesion bypass, and mutagenesis.

Xu, Liang; Wang, Wei;Wu, Jiabin; Shin, JiHyun; Wang,Pengcheng; Unarta,Ilona Christy; Chong ...


28784758

2017

Mercury-induced epigenetic transgenerationalinheritance of abnormal neurobehavior is correlatedwit ...

Carvan 3rd, Michael J;Kalluvila, Thomas A;Klingler, Rebekah H;Larson, Jeremy K;Pickens, Mat ...

R01ES012974,R01ES012974

PLoS One (2017) 28464002

2017

Metabolism disrupting chemicals and metabolicdisorders.

Heindel, Jerrold J;Blumberg, Bruce; Cave,Mathew; Machtinger,Ronit; Mantovani,Alberto; Mende ...

R01ES023316,R01ES023316

Reprod Toxicol (2017 03) 27760374

2017

Methodology to Identify Poly-ADP-RibosePolymerase 1 (PARP1)-mRNA Targets by PAR-CLiP.

Melikishvili, Manana;Matveeva, Elena;Fondufe-Mittendorf,Yvonne


2017

Mfd Protein and Transcription-Repair Coupling inEscherichia coli.

Selby, Christopher P R01ES027255 Photochem Photobiol(2017 01)

27864884

2017

Mfd translocase is necessary and sufficient fortranscription-coupled repair in Escherichia coli.

Adebali, Ogun; Sancar,Aziz; Selby,Christopher P

R01ES027255 J Biol Chem (2017 11 10) 28986449

2017

Microarray dataset of transient and permanent DNAmethylation changes in HeLa cells undergoing inorg ...

Eckstein, Meredith;Rea, Matthew;Fondufe-Mittendorf,Yvonne N

R01ES024478 Data Brief (2017 Aug) 28589171

2017

MicroRNAs Induce a Permissive ChromatinEnvironment that Enables Neuronal Subtype-SpecificReprogram ...

Abernathy, Daniel G;Kim, Woo Kyung;McCoy, Matthew J;Lake, Allison M;Ouwenga, Rebecca;Lee, ...

U24ES026699 Cell Stem Cell (2017 0907)

28886366

2017

miR-155 mediates arsenic trioxide resistance byactivating Nrf2 and suppressing apoptosis in lung ca ...

Gu, Shiyan; Lai,Yanhao; Chen, Hongyu;Liu, Yuan; Zhang,Zunzhen

R01ES023569 Sci Rep (2017 09 22) 28939896

2017

Modulation of trinucleotide repeat instability by DNApolymerase β polymorphic variant R137Q.

Ren, Yaou; Lai,Yanhao; Laverde,Eduardo E; Lei,Ruipeng; Rein, HayleyL; Liu, Yuan

R01ES023569 PLoS One (2017) 28475635

2017

Molecular mechanisms and genomic maps of DNAexcision repair in Escherichia coli and humans.

Hu, Jinchuan; Selby,Christopher P; Adar,Sheera; Adebali, Ogun;Sancar, Aziz

P30ES010126,R01ES027255

J Biol Chem (2017 09 22) 28798238

2017

Multivariate Bayesian variable selection exploitingdependence structure among outcomes: Application ...

Lee, Kyu Ha; Tadesse,Mahlet G; Baccarelli,Andrea A; Schwartz,Joel; Coull, Brent A

P30ES000002,P30ES009089,R01ES027747

Biometrics (2017 03) 27377873

2017

Mutagenicity of a Model DNA-Peptide Cross-Link inHuman Cells: Roles of Translesion Synthesis DNA Po...

Pande, Paritosh; Ji,Shaofei; Mukherjee,Shivam; Schärer,Orlando D; Tretyakova,Natalia Y; Bas ...

R01ES023350 Chem Res Toxicol (2017Feb 20)

27951635

2017

Nanoarmoring: strategies for preparation ofmulti-catalytic enzyme polymer conjugates andenhancemen ...

Zore, Omkar V; Pande,Paritosh; Okifo,Oghenenyerovwo;Basu, Ashis K; Kasi,Rajeswari M; Kumar, ...

R01ES023350 RSC Adv (2017) 29403641

2017

Nickel induces transcriptional down-regulation ofDNA repair pathways in tumorigenic and non-tumorig...

Scanlon, Susan E;Scanlon, Christine D;Hegan, Denise C;Sulkowski, Parker L;Glazer, Peter M

R01ES005775 Carcinogenesis (2017 0601)

28472268

2017

Nickel-induced HIF-1α promotes growth arrest andsenescence in normal human cells but lacks toxic ef ...



28552779

2017

Nonsynonymous Polymorphisms in the HumanAS3MT Arsenic Methylation Gene: Implications forArsenic To ...

Li, Jiaojiao;Packianathan, Charles;Rossman, Toby G;Rosen, Barry P


28537708

2017

Nrf2 regulates gene-environment interactions in ananimal model of intrauterine inflammation: Implic ...

Sussan, Thomas E;Sudini, Kuladeep;Talbot Jr, C Conover;Wang, Xiaobin;Wills-Karp, Marsha; Bu...

U01ES026721 Sci Rep (2017 01 10) 28071748

2017

Nucleosome Histone Tail Conformation andDynamics: Impacts of Lysine Acetylation and aNearby Minor ...

Fu, Iwen; Cai, Yuqin;Geacintov, Nicholas E;Zhang, Yingkai;Broyde, Suse


2017

Nucleosome-like, Single-stranded DNA(ssDNA)-Histone Octamer Complexes and theImplication for DNA D ...

Adkins, Nicholas L;Swygert, Sarah G; Kaur,Parminder; Niu,Hengyao; Grigoryev,Sergei A; Sung, ...

P30ES025128,R01ES007061

J Biol Chem (2017 Mar31)

28202543

2017

Nucleotide Excision Repair Lesion-RecognitionProtein Rad4 Captures a Pre-Flipped Partner Base in a...

Mu, Hong; Geacintov,Nicholas E; Min,Jung-Hyun; Zhang,Yingkai; Broyde, Suse


28460163

2017

Nucleotide Excision Repair: Finely Tuned MolecularOrchestra of Early Pre-incision Events.

Zhu, Qianzheng; Wani,Altaf A


27696486

2017

Nucleotide selectivity defect and mutator phenotypeconferred by a colon cancer-associated DNA polym ...

Mertz, T M;Baranovskiy, A G;Wang, J; Tahirov, T H;Shcherbakova, P V

R01ES015869 Oncogene (2017 Aug) 28368425

2017

PARPi focus the spotlight on replication forkprotection in cancer.

Schlacher, Katharina R01ES029680 Nat Cell Biol (2017 Oct31)

29087384

2017

Plasticity of the Mre11-Rad50-Xrs2-Sae2 nucleaseensemble in the processing of DNA-bound obstacles.

Wang, Weibin; Daley,James M; Kwon,Youngho; Krasner,Danielle S; Sung,Patrick

R01ES007061 Genes Dev (2017 12 01) 29321177

2017

PostExcision Events in Human Nucleotide ExcisionRepair.

Kemp, Michael G; Hu,Jinchuan


27645806

2017

Prenatal arsenic exposure alters REST/NRSF andmicroRNA regulators of embryonic neural stem cellfat ...

Tyler, Christina R;Labrecque, Matthew T;Solomon, Elizabeth R;Guo, Xun; Allan,Andrea M

R01ES019583 Neurotoxicol Teratol (2017Jan - Feb)

27751817

2017

Protection of Nrf2 against arsenite-induced oxidativedamage is regulated by the cyclic guanosine mo ...

Chen, Chengzhi; Jiang,Xuejun; Gu, Shiyan;Lai, Yanhao; Liu, Yuan;Zhang, Zunzhen

R01ES023569 Environ Toxicol (2017Aug)

27774770

2017

Rapid Recall Ability of Memory T cells is Encoded intheir Epigenome.

Barski, Artem;Cuddapah, Suresh;Kartashov, Andrey V;Liu, Chong; Imamichi,Hiromi; Yang, Wenj ...

R01ES024727 Sci Rep (2017 01 05) 28054639

2017

Recurrent horizontal transfer of arsenitemethyltransferase genes facilitated adaptation of life to...

Chen, Song-Can; Sun,Guo-Xin; Rosen, BarryP; Zhang, Si-Yu; Deng,Ye; Zhu, Bo-Kai;Rensing, C ...

R01ES023779 Sci Rep (2017 08 10) 28798375

2017

Redox dynamics of manganese as a mitochondriallife-death switch.

Smith, Matthew Ryan;Fernandes, Jolyn; Go,Young-Mi; Jones, DeanP

R01ES023485 Biochem Biophys ResCommun (2017 01 15)

28212723

2017

Redox theory of aging: implications for health anddisease.

Go, Young-Mi; Jones,Dean P

P30ES019776,R01ES023485

Clin Sci (Lond) (2017 Jul15)

28667066

2017

Regulation of drug metabolism and toxicity bymultiple factors of genetics, epigenetics, lncRNAs, gu...

Yu, Ai-Ming;Ingelman-Sundberg,Magnus; Cherrington,Nathan J; Aleksunes,Lauren M; Zanger, Ulr...

P30ES005022,P30ES006694,P30ES010126,R01ES024421

Acta Pharm Sin B (201703)

28388695

2017

Relevance of iPSC-derived human PGC-like cells atthe surface of embryoid bodies to prechemotaxis mi ...

Mitsunaga, Shino;Odajima, Junko;Yawata, Shiomi;Shioda, Keiko; Owa,Chie; Isselbacher, Kurt...

R01ES023316,R01ES023316


29087313

2017

Removal of oxidatively generated DNA damage byoverlapping repair pathways.

Shafirovich, Vladimir;Geacintov, Nicholas E

R01ES027059 Free Radic Biol Med (201706)

27818219

2017

Repair-Resistant DNA Lesions. Geacintov, Nicholas E;Broyde, Suse


28750166

2017

Replication and repair of a reduced2΄-deoxyguanosine-abasic site interstrand cross-link inhuman ce ...

Price, Nathan E; Li, Lin;Gates, Kent S; Wang,Yinsheng

R01ES021007,T32ES018827

Nucleic Acids Res (2017Jun 20)

28431012

2017

Replicative DNA polymerase defects in humancancers: Consequences, mechanisms, and implicationsfor ...

Barbari, Stephanie R;Shcherbakova, Polina V


28687338

2017

Reply to "Comment on 'On the Utility of ToxCast™and ToxPi as Methods for Identifying New Obesogens'...

Janesick, Amanda S;Dimastrogiovanni,Giorgio;Chamorro-Garcia,Raquel; Blumberg,Bruce

R01ES023316,R01ES023316


28055946

2017

Retinoid X Receptor Activation Alters the ChromatinLandscape To Commit Mesenchymal Stem Cells to th...

Shoucri, Bassem M;Martinez, Eric S;Abreo, Timothy J;Hung, Victor T;Moosova, Zdena;Shioda, ...

R01ES023316,R01ES023316


28977589

2017

Reversible DNA-Protein Cross-Linking at EpigeneticDNA Marks.

Ji, Shaofei; Shao,Hongzhao; Han,Qiyuan; Seiler,Christopher L;Tretyakova, Natalia Y

R01ES023350 Angew Chem Int Ed Engl(2017 11 06)

28898504

2017

Role of DNA polymerase β oxidized nucleotideinsertion in DNA ligation failure.

Çaglayan, Melike;Wilson, Samuel H

R00ES026191 J Radiat Res (2017 Sep 01) 28992331

2017

Role of the Pif1-PCNA Complex in Pol δ-DependentStrand Displacement DNA Synthesis andBreak-Induced ...

Buzovetsky, Olga;Kwon, Youngho; Pham,Nhung Tuyet; Kim,Claire; Ira, Grzegorz;Sung, Patrick; ...

R01ES007061 Cell Rep (2017 Nov 14) 29141206

2017

Selective Nrf2 Gene Deletion in the RostralVentrolateral Medulla Evokes Hypertension andSympathoex ...

Gao, Lie; Zimmerman,Matthew C; Biswal,Shyam; Zucker, IrvingH

U01ES026721 Hypertension (2017 06) 28461605

2017

SENP8 limits aberrant neddylation of NEDD8pathway components to promote cullin-RINGubiquitin ligas ...

Coleman, Kate E;Békés, Miklós;Chapman, Jessica R;Crist, Sarah B; Jones,Mathew Jk; Ueberheid...

R01ES025166 Elife (2017 05 05) 28475037

2017

Sequence imperfections and base triplet recognition bythe Rad51/RecA family of recombinases.

Lee, Ja Yil; Steinfeld,Justin B; Qi, Zhi;Kwon, YoungHo; Sung,Patrick; Greene, Eric C

R01ES007061 J Biol Chem (2017 06 30) 28476890

2017

Sequence-Specific Covalent Capture Coupled withHigh-Contrast Nanopore Detection of aDisease-Derive ...

Nejad, Maryam Imani;Shi, Ruicheng; Zhang,Xinyue; Gu, Li-Qun;Gates, Kent S

R01ES021007 Chembiochem (2017 0718)

28422400

2017

Sex-Differential Responses of TumorPromotion-Associated Genes and Dysregulation ofNovel Long Nonco ...

Lodato, Nicholas J;Melia, Tisha;Rampersaud, Andy;Waxman, David J

R01ES024421 Toxicol Sci (2017 09 01) 28903501

2017

Sexually Dimorphic Effects of Early-Life Exposuresto Endocrine Disruptors: Sex-Specific Epigenetic ...

McCabe, Carolyn;Anderson, Olivia S;Montrose, Luke; Neier,Kari; Dolinoy, Dana C

P30ES017885,T32ES007062,U01ES026697


28980159

2017

Structure-activity relationships among DNA ligaseinhibitors: Characterization of a selective uncomp ...

Howes, Timothy R L;Sallmyr, Annahita;Brooks, Rhys; Greco,George E; Jones, DarinE; Matsumoto ...


29078112

2017

TALEN-Mediated FLAG-Tagging of EndogenousHistone Methyltransferase DOT1L.

An, Cheng; Zhu,Guangjing; Martos,Suzanne N; Feng, Xue;Zhang, Haimou; Jia,Yankai; Wang, Zh ...

R01ES025761,R01ES025761

Adv Biosci Biotechnol(2017 Sep)

29796335

2017

The association between telomere length and mortalityin Bangladesh.

Dean, Samantha G;Zhang, Chenan; Gao,Jianjun; Roy, Shantanu;Shinkle, Justin;Sabarinathan, M ...

P42ES010349,R35ES028379

Aging (Albany NY) (2017Jun 15)

28630379

2017

The Cartography of UV-induced DNA DamageFormation and DNA Repair.

Hu, Jinchuan; Adar,Sheera


27861959

2017

The essential kinase ATR: ensuring faithfulduplication of a challenging genome.

Saldivar, Joshua C;Cortez, David;Cimprich, Karlene A


28811666

2017

The Human Ligase IIIα-XRCC1 Protein ComplexPerforms DNA Nick Repair after TransientUnwrapping of N ...

Cannan, Wendy J;Rashid, Ishtiaque;Tomkinson, Alan E;Wallace, Susan S;Pederson, David S

R01ES012512 J Biol Chem (2017 Mar31)

28184006

2017

The Nonbulky DNA Lesions Spiroiminodihydantoinand 5-Guanidinohydantoin Significantly Block HumanRN ...

Kolbanovskiy, Marina;Chowdhury, MoinuddinA; Nadkarni, Aditi;Broyde, Suse;Geacintov, Nichola ...

R01ES025987,R01ES027059

Biochemistry (2017 06 20) 28514164

2017

The unexpected teratogenicity of RXR antagonistUVI3003 via activation of PPARγ in Xenopus tropicali...

Zhu, Jingmin; Janesick,Amanda; Wu, Lijiao;Hu, Lingling; Tang,Weiyi; Blumberg,Bruce; Shi, ...

R01ES023316,R01ES023316

Toxicol Appl Pharmacol(2017 Jan 01)

27894914

2017

Tissue-specific DNA methylation is conserved acrosshuman, mouse, and rat, and driven by primary seq ...

Zhou, Jia; Sears, ReneeL; Xing, Xiaoyun;Zhang, Bo; Li, Daofeng;Rockweiler, Nicole B;Jang, ...

U24ES026699 BMC Genomics (2017 Sep12)

28899353

2017

Transient and permanent changes in DNA methylationpatterns in inorganic arsenic-mediated epithelial ...

Eckstein, Meredith;Rea, Matthew;Fondufe-Mittendorf,Yvonne N


28336213

2017

Translesion synthesis DNA polymerases promoteerror-free replication through the minor-groove DNAad ...

Yoon, Jung-Hoon; RoyChoudhury, Jayati;Park, Jeseong; Prakash,Satya; Prakash, Louise

R01ES022948 J Biol Chem (2017 11 10) 28939775

2017

Translesion Synthesis of 2'-Deoxyguanosine Lesionsby Eukaryotic DNA Polymerases.

Basu, Ashis K; Pande,Paritosh; Bose,Arindam

R01ES021762,R01ES023350


27760288

2017

Two approaches reveal a new paradigm of 'switchableor genetics-influenced allele-specific DNA methy ...

Martos, Suzanne N; Li,Teng; Ramos, RamonBossardi; Lou, Dan;Dai, Hongzheng; Xu,Jin-Chong; G ...

R01ES025761,R01ES025761,T32ES007141

Cell Discov (2017) 29387450

2017

Ultrathin Graphene-Protein Supercapacitors forMiniaturized Bioelectronics.

Mosa, Islam M;Pattammattel, Ajith;Kadimisetty, Karteek;Pande, Paritosh;El-Kady, Maher F; Bi...

R01ES023350 Adv Energy Mater (2017Sep 06)

29104523

2017

Uncovering the transcriptomic and epigenomiclandscape of nicotinic receptor genes in non-neuronal t...

Zhang, Bo; Madden,Pamela; Gu, Junchen;Xing, Xiaoyun; Sankar,Savita; Flynn, Jennifer;Kroll, ...

U24ES026699 BMC Genomics (2017 0605)

28583088

2017

UV radiation-induced SUMOylation of DDB2regulates nucleotide excision repair.

Han, Chunhua; Zhao,Ran; Kroger, John; He,Jinshan; Wani, Gulzar;Wang, Qi-En; Wani,Altaf A

R01ES012991 Carcinogenesis (2017 1001)

28981631

2017

UV-induced proteolysis of RNA polymerase II ismediated by VCP/p97 segregase and timelyorchestratio ...

He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Wani, Altaf A

R01ES012991 Oncotarget (2017 Feb 14) 28036256

2017

Variation in Extracellular Detoxification Is a Link toDifferent Carcinogenicity among Chromates in ...

Krawic, Casey; Luczak,Michal W; Zhitkovich,Anatoly


28759204

2017

Whole-Genome DNA Methylation Profiling IdentifiesEpigenetic Signatures of Uterine Carcinosarcoma.

Li, Jing; Xing,Xiaoyun; Li, Daofeng;Zhang, Bo; Mutch,David G; Hagemann,Ian S; Wang, Ting

U24ES026699 Neoplasia (2017 02) 28088687

2017

Whole-transcriptome analysis delineates the humanplacenta gene network and its associations with fe ...

Deyssenroth, Maya A;Peng, Shouneng; Hao,Ke; Lambertini, Luca;Marsit, Carmen J; Chen,Jia

P30ES023515,R01ES025145,R01ES025145,R24ES028507

BMC Genomics (2017 0710)

28693416

2017

xMSannotator: An R Package for Network-BasedAnnotation of High-Resolution Metabolomics Data.

Uppal, Karan; Walker,Douglas I; Jones, DeanP

P30ES019776,R01ES023485

Anal Chem (2017 01 17) 27977166

2017

Yale school of public health symposium on lifetimeexposures and human health: the exposome; summary...

Johnson, Caroline H;Athersuch, Toby J;Collman, Gwen W;Dhungana, Suraj; Grant,David F; Jones ...

P30ES019776,R01ES023485,U2CES026560

Hum Genomics (2017 Dec08)

29221465

2017

Yeast DNA polymerase ζ maintains consistent activityand mutagenicity across a wide range of physiol ...

Kochenova, Olga V;Bezalel-Buch, Rachel;Tran, Phong; Makarova,Alena V; Chabes,Andrei; Burger ...


28180291

2017

Yeast Srs2 Helicase Promotes Redistribution ofSingle-Stranded DNA-Bound RPA and Rad52 inHomologous ...

De Tullio, Luisina;Kaniecki, Kyle; Kwon,Youngho; Crickard, JBrooks; Sung, Patrick;Greene, ...

R01ES007061 Cell Rep (2017 Oct 17) 29045827

2017

Aberrant DNA Methylation of Phosphodiesterase[corrected] 4D Alters Airway Smooth Muscle CellPhenot ...

Lin, Amanda H Y;Shang, Yan; Mitzner,Wayne; Sham, James SK; Tang, Wan-yee

R01ES024784 Am J Respir Cell Mol Biol(2016 Feb)

26181301

2016

An essential role for UTX in resolution and activationof bivalent promoters.

Dhar, Shilpa S; Lee,Sung-Hun; Chen, Kaifu;Zhu, Guangjing; Oh,WonKyung; Allton,Kendra; Gafn ...

R01ES025761,R01ES025761


26762983

2016

Ancestral vinclozolin exposure alters the epigenetictransgenerational inheritance of sperm small no ...

Schuster, Andrew;Skinner, Michael K;Yan, Wei

R01ES012974,R01ES012974


2016

AP endonuclease 1 prevents the extension of a T/Gmismatch by DNA polymerase β to prevent mutations...

Lai, Yanhao; Jiang,Zhongliang; Zhou, Jing;Osemota, Emmanuel;Liu, Yuan


27183823

2016

Arsenic Directly Binds to and Activates the YeastAP-1-Like Transcription Factor Yap8.

Kumar, Nallani Vijay;Yang, Jianbo; Pillai,Jitesh K; Rawat, Swati;Solano, Carlos; Kumar,Abh ...

R01ES023779 Mol Cell Biol (2016 Mar) 26711267

2016

ATR- and ATM-Mediated DNA Damage Response IsDependent on Excision Repair Assembly during G1but Not ...

Ray, Alo; Blevins,Chessica; Wani, Gulzar;Wani, Altaf A

R01ES012991 PLoS One (2016) 27442013

2016

Bypass of DNA-Protein Cross-links Conjugated to the7-Deazaguanine Position of DNA by Translesion Sy ...

Wickramaratne, Susith;Ji, Shaofei; Mukherjee,Shivam; Su, Yan;Pence, Matthew G;Lior-Hoffmann ...

R01ES010546,R01ES023350,R01ES025987

J Biol Chem (2016 Nov04)

27621316

2016

Chemical and Hormonal Effects onSTAT5b-Dependent Sexual Dimorphism of the LiverTranscriptome.

Oshida, Keiyu;Waxman, David J;Corton, J Christopher

R01ES024421 PLoS One (2016) 26959237

2016

Cisplatin DNA damage and repair maps of the humangenome at single-nucleotide resolution.

Hu, Jinchuan; Lieb,Jason D; Sancar, Aziz;Adar, Sheera

P30ES010126,R01ES027255


27688757

2016

Comparative analysis of linker histone H1, MeCP2,and HMGD1 on nucleosome stability and target site ...

Riedmann, Caitlyn;Fondufe-Mittendorf,Yvonne N

R01ES024478 Sci Rep (2016 09 14) 27624769

2016

Comparative Error-Free and Error-Prone TranslesionSynthesis of N(2)-2'-Deoxyguanosine Adducts Forme...

Bose, Arindam;Surugihalli, Chaitra;Pande, Paritosh;Champeil, Elise; Basu,Ashis K


27082015

2016

Computational Metabolomics: A Framework for theMillion Metabolome.

Uppal, Karan; Walker,Douglas I; Liu, Ken; Li,Shuzhao; Go,Young-Mi; Jones, DeanP

P30ES019776,R01ES023485,T32ES012870,U2CES026560


27629808

2016

Concerns over use of glyphosate-based herbicides andrisks associated with exposures: a consensus st ...

Myers, John Peterson;Antoniou, Michael N;Blumberg, Bruce;Carroll, Lynn; Colborn,Theo; Evere ...

R01ES023316,R01ES023316

Environ Health (2016 Feb17)

26883814

2016

Covalent DNA-Protein Cross-Linking byPhosphoramide Mustard and Nornitrogen Mustard inHuman Cells.

Groehler 4th, Arnold;Villalta, Peter W;Campbell, Colin;Tretyakova, Natalia

R01ES023350 Chem Res Toxicol (2016Feb 15)

26692166

2016

Crosstalk between MSH2-MSH3 and polβ promotestrinucleotide repeat expansion during base excision re...

Lai, Yanhao; Budworth,Helen; Beaver, Jill M;Chan, Nelson L S;Zhang, Zunzhen;McMurray, Cynt ...

R01ES023569 Nat Commun (2016 08 22) 27546332

2016

Deployment-Associated Exposure Surveillance WithHigh-Resolution Metabolomics.

Walker, Douglas I;Mallon, Col TimothyM; Hopke, Philip K;Uppal, Karan; Go,Young-Mi; Rohrbeck ...

P30ES019776,R01ES023485,T32ES012870


27501099

2016

Developmental origins of epigenetic transgenerationalinheritance.

Hanson, Mark A;Skinner, Michael K

R01ES012974,R01ES012974


2016

Different ATM Signaling in Response toChromium(VI) Metabolism via Ascorbate andNonascorbate Reduct ...

Luczak, Michal W;Green, Samantha E;Zhitkovich, Anatoly

R01ES008786 Environ Health Perspect(2016 Jan)

25977998

2016

Differential DNA lesion formation and repair inheterochromatin and euchromatin.

Han, Chunhua;Srivastava, AmitKumar; Cui, Tiantian;Wang, Qi-En; Wani,Altaf A

R01ES012991 Carcinogenesis (2016 Feb) 26717995

2016

Differential DNA methylation analysis optimallyrequires purified cell populations.

Skinner, Michael K R01ES012974,R01ES012974

Fertil Steril (2016 09 01) 27349925

2016

Directed evolution using dCas9-targeted somatichypermutation in mammalian cells.

Hess, Gaelen T;Frésard, Laure; Han,Kyuho; Lee, CameronH; Li, Amy; Cimprich,Karlene A; Mont ...

R01ES016486 Nat Methods (2016 Dec) 27798611

2016

Effective molarity in a nucleic acid-controlled reaction.

Catalano, Michael J;Price, Nathan E; Gates,Kent S

R01ES021007 Bioorg Med Chem Lett(2016 06 01)

27117430

2016

Endocrine disruptors in 2015: Epigenetictransgenerational inheritance.


Nat Rev Endocrinol (2016Feb)

26585656

2016

Enrichment of Cdk1-cyclins at DNA double-strandbreaks stimulates Fun30 phosphorylation and DNAend ...

Chen, Xuefeng; Niu,Hengyao; Yu, Yang;Wang, Jingjing; Zhu,Shuangyi; Zhou, Jianjie;Papusha, ...

R01ES007061 Nucleic Acids Res (2016Apr 07)

26801641

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Epigenetic programming alterations in alligators fromenvironmentally contaminated lakes.

Guillette Jr, Louis J;Parrott, Benjamin B;Nilsson, Eric; Haque, MM; Skinner, Michael K

R01ES012974,R01ES012974

Gen Comp Endocrinol(2016 11 01)

27080547

2016

Epigenetic Therapeutics: A New Weapon in the WarAgainst Cancer.

Ahuja, Nita; Sharma,Anup R; Baylin,Stephen B

R01ES011858 Annu Rev Med (2016) 26768237

2016

Erasure of DNA methylation, genomic imprints, andepimutations in a primordial germ-cell model deriv ...

Miyoshi, Norikatsu;Stel, Jente M; Shioda,Keiko; Qu, Na;Odajima, Junko;Mitsunaga, Shino; Zh ...

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27486249

2016

Estrogen Drives Cellular Transformation andMutagenesis in Cells Expressing the BreastCancer-Associ ...

Nemec, Antonia A;Bush, Korie B;Towle-Weicksel, JamieB; Taylor, B Frazier;Schulz, Vincent; W ...


2016

Evolution of Telomeres in Schizosaccharomycespombe and Its Possible Relationship to the Diversifica...

Sepsiova, Regina;Necasova, Ivona;Willcox, Smaranda;Prochazkova, Katarina;Gorilak, Peter; No ...

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2016

Exposure Memory and Lung Regeneration. Go, Young-Mi; Jones,Dean P

R01ES023485 Ann Am Thorac Soc (201612)

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Expression of arsenic resistance genes in the obligateanaerobe Bacteroides vulgatus ATCC 8482, a gu ...

Li, Jiaojiao; Mandal,Goutam; Rosen, BarryP

R01ES023779 Anaerobe (2016 Jun) 27040269

2016

Genomic Clustering of differential DNA methylatedregions (epimutations) associated with the epigene ...

Haque, M Muksitul;Nilsson, Eric E; Holder,Lawrence B; Skinner,Michael K

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BMC Genomics (2016 0601)

27245821

2016

How SUMOylation Fine-Tunes the Fanconi AnemiaDNA Repair Pathway.


R01ES025166 Front Genet (2016) 27148358

2016

HUWE1 comes to the rescue at stalled replicationforks.


R01ES025166 EMBO Rep (2016 06) 27146074

2016

HUWE1 interacts with PCNA to alleviate replicationstress.

Choe, Katherine N;Nicolae, Claudia M;Constantin, Daniel;Imamura Kawasawa,Yuka; Delgado-Diaz, ...

R01ES026184 EMBO Rep (2016 06) 27146073

2016

Hydrogen peroxide and central redox theory foraerobic life: A tribute to Helmut Sies: Scout, trailb ...

Jones, Dean P P30ES019776,R01ES023485,U2CES026560

Arch Biochem Biophys(2016 Apr 01)

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2016

In Vitro Lesion Bypass Studies ofO(4)-Alkylthymidines with Human DNA Polymeraseη.

Williams, Nicole L;Wang, Pengcheng; Wu,Jiabin; Wang, Yinsheng

R01ES025121 Chem Res Toxicol (2016Apr 18)

27002924

2016

Inhibiting Mitochondrial DNA Ligase IIIα ActivatesCaspase 1-Dependent Apoptosis in Cancer Cells.

Sallmyr, Annahita;Matsumoto, Yoshihiro;Roginskaya, Vera; VanHouten, Bennett;Tomkinson, Alan ...

R01ES012512 Cancer Res (2016 09 15) 27503931

2016

Inhibition of DNA Methyltransferases Blocks MutantHuntingtin-Induced Neurotoxicity.

Pan, Yanchun; Daito,Takuji; Sasaki, Yo;Chung, Yong Hee;Xing, Xiaoyun;Pondugula, Santhi; Sw...

U24ES026699 Sci Rep (2016 08 12) 27516062

2016

Inhibition of ileal bile acid uptake protects againstnonalcoholic fatty liver disease in high-fat d ...

Rao, Anuradha;Kosters, Astrid; Mells,Jamie E; Zhang,Wujuan; Setchell,Kenneth D R; Amanso,...

P30ES019776,R01ES023485

Sci Transl Med (2016 0921)

27655848

2016

Involvement of PARP1 in the regulation of alternativesplicing.

Matveeva, Elena;Maiorano, John; Zhang,Qingyang; Eteleeb,Abdallah M;Convertini, Paolo;Chen, ...

R01ES024478 Cell Discov (2016) 27462443

2016

Low-dose oral cadmium increases airway reactivityand lung neuronal gene expression in mice.

Chandler, Joshua D;Wongtrakool, Cherry;Banton, Sophia A; Li,Shuzhao; Orr, MichaelL; Barr, ...

R01ES023485,T32ES012870

Physiol Rep (2016 Jul) 27401458

2016

Mass Spectrometry-Based Quantitative Strategies forAssessing the Biological Consequences and Repair ...

You, Changjun; Wang,Yinsheng

R01ES025121 Acc Chem Res (2016 Feb16)

26758048

2016

Maternal serum perfluoroalkyl substances duringpregnancy and duration of breastfeeding.

Romano, Megan E; Xu,Yingying; Calafat,Antonia M; Yolton,Kimberly; Chen, Aimin;Webster, Gle ...

P30ES006096,R01ES025214

Environ Res (2016 08) 27179585

2016

Mek1 Down Regulates Rad51 Activity during YeastMeiosis by Phosphorylation of Hed1.

Callender, Tracy L;Laureau, Raphaelle;Wan, Lihong; Chen,Xiangyu; Sandhu,Rima; Laljee, Saif ...

R01ES007061 PLoS Genet (2016 Aug) 27483004

2016

Metabolic Pathways and Networks Associated WithTobacco Use in Military Personnel.

Jones, Dean P; Walker,Douglas I; Uppal,Karan; Rohrbeck,Patricia; Mallon, ColTimothy M; Go, ...

P30ES019776,R01ES023485,T32ES012870


27501098

2016

Metabolic pathways of lung inflammation revealed byhigh-resolution metabolomics (HRM) of H1N1 influ ...

Chandler, Joshua D; Hu,Xin; Ko, Eun-Ju; Park,Soojin; Lee,Young-Tae; Orr,Michael; Fernandes ...

R01ES023485 Am J Physiol Regul IntegrComp Physiol (2016 11 01)

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2016

Metabolomics and Mycobacterial Disease: Don'tForget the Bioinformatics.

Collins, Jeffrey M;Kempker, Russell R;Ziegler, Thomas R;Blumberg, Henry M;Jones, Dean P

P30ES019776,R01ES023485,T32ES012870

Ann Am Thorac Soc (2016Jan)

26730872

2016

miR-155 Overexpression Promotes GenomicInstability by Reducing High-fidelity PolymeraseDelta Expre ...

Czochor, Jennifer R;Sulkowski, Parker;Glazer, Peter M

R01ES005775 Mol Cancer Res (2016Apr)

26850462

2016

Mismatch repair proteins recruit DNAmethyltransferase 1 to sites of oxidative DNA damage.

Ding, Ning; Bonham,Emily M; Hannon,Brooke E; Amick,Thomas R; Baylin,Stephen B; O'Hagan,He ...

R01ES011858 J Mol Cell Biol (2016 06) 26186941

2016

New mechanisms of bacterial arsenic resistance. Yang, Hung-Chi;Rosen, Barry P

R01ES023779 Biomed J (2016 Feb) 27105594

2016

Nuclear Factor κB1/RelA Mediates Inflammation inHuman Lung Epithelial Cells at Atmospheric OxygenL ...

Jagannathan,Lakshmanan; Jose,Cynthia C; Arita,Adriana; Kluz, Thomas;Sun, Hong; Zhang,Xiao ...

P30ES000260,R01ES024727

J Cell Physiol (2016 Jul) 26588041

2016

Nuclear Thioredoxin-1 Overexpression AttenuatesAlcohol-Mediated Nrf2 Signaling and Lung Fibrosis.

Sueblinvong, Viranuj;Mills, Stephen T;Neujahr, David C; Go,Young-Mi; Jones, DeanP; Guidot, ...

R01ES023485 Alcohol Clin Exp Res(2016 09)

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2016

Obesogens: an emerging threat to public health. Janesick, Amanda S;Blumberg, Bruce

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On the Utility of ToxCast™ and ToxPi as Methods forIdentifying New Obesogens.

Janesick, AmandaShaine;Dimastrogiovanni,Giorgio; Vanek, Lenka;Boulos, Christy;Chamorro-Garc ...

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2016

Oxidative stress under ambient and physiologicaloxygen tension in tissue culture.

Jagannathan,Lakshmanan;Cuddapah, Suresh;Costa, Max

P30ES000260,R01ES024727

Curr Pharmacol Rep (2016Apr)

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PARP10 deficiency manifests by severedevelopmental delay and DNA repair defect.

Shahrour, Maher Awni;Nicolae, Claudia M;Edvardson, Simon;Ashhab, Motee; Galvan,Adri M; Cons ...

R01ES026184 Neurogenetics (2016 10) 27624574

2016

Patterns of growth and tract formation during the earlydevelopment of secondary lineages in the Dro ...

Lovick, Jennifer K;Kong, Angel; Omoto,Jaison J; Ngo, Kathy T;Younossi-Hartenstein,Amelia; H ...

R01ES029357 Dev Neurobiol (2016 Apr) 26178322

2016

Placental Epigenetics in Children's EnvironmentalHealth.

Marsit, Carmen J P01ES022832,R01ES025145,R01ES025145

Semin Reprod Med (2016Jan)

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Proliferating cell nuclear antigen preventstrinucleotide repeat expansions by promoting repeatdele ...

Beaver, Jill M; Lai,Yanhao; Rolle, ShantellJ; Liu, Yuan


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Promotion of RAD51-Mediated Homologous DNAPairing by the RAD51AP1-UAF1 Complex.

Liang, Fengshan;Longerich, Simonne;Miller, Adam S; Tang,Caroline; Buzovetsky,Olga; Xiong, ...

R01ES007061 Cell Rep (2016 06 07) 27239033

2016

Quantitative Mass Spectrometry Reveals Changes inHistone H2B Variants as Cells Undergo Inorganic Ar...

Rea, Matthew; Jiang,Tingting; Eleazer,Rebekah; Eckstein,Meredith; Marshall,Alan G; Fondufe- ...

R01ES024478 Mol Cell Proteomics (201607)

27169413

2016

Recognition of Lys48-Linked Di-ubiquitin andDeubiquitinating Activities of the SARS CoronavirusPap ...

Békés, Miklós; van derHeden van Noort,Gerbrand J; Ekkebus,Reggy; Ovaa, Huib;Huang, Tony T; ...

R01ES025166 Mol Cell (2016 05 19) 27203180

2016

Replicative Bypass of O2-Alkylthymidine Lesions inVitro.

Williams, Nicole L;Wang, Pengcheng;Wang, Yinsheng


27611246

2016

Reply. Janesick, Amanda S;Blumberg, Bruce

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2016

Reprogramming of the Epigenome by MLL1 LinksEarly-Life Environmental Exposures to ProstateCancer R ...

Wang, Quan; Trevino,Lindsey S; Wong,Rebecca Lee Yean;Medvedovic, Mario;Chen, Jing; Ho, Shu ...

P30ES006096,U01ES026719

Mol Endocrinol (2016Aug)

27219490

2016

Roles of Aag, Alkbh2, and Alkbh3 in the Repair ofCarboxymethylated and Ethylated Thymidine Lesions.

You, Changjun; Wang,Pengcheng; Nay,Stephanie L; Wang,Jianshuang; Dai,Xiaoxia; O'Connor, Ti...

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26930515

2016

SCR7 is neither a selective nor a potent inhibitor ofhuman DNA ligase IV.

Greco, George E;Matsumoto, Yoshihiro;Brooks, Rhys C; Lu,Zhengfei; Lieber,Michael R; Tomkins ...


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2016

Sequencing the exposome: A call to action. Jones, Dean P P30ES019776,R01ES023485,T32ES012870

Toxicol Rep (2016) 26722641

2016

Simple, High-Yield Syntheses of DNA DuplexesContaining Interstrand DNA-DNA Cross-LinksBetween an N ...

Gamboa Varela,Jacqueline; Gates, KentS

R01ES021007 Curr Protoc Nucleic AcidChem (2016 06 01)

27248783

2016

Small Molecule Inhibitor of NRF2 SelectivelyIntervenes Therapeutic Resistance inKEAP1-Deficient NS ...

Singh, Anju;Venkannagari,Sreedhar; Oh, Kyu H;Zhang, Ya-Qin; Rohde,Jason M; Liu, Li;Nimmag ...

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27552339

2016

Statistical Approaches for Assessing Health Effects ofEnvironmental Chemical Mixtures in Epidemiolo ...

Taylor, Kyla W;Joubert, Bonnie R;Braun, Joe M; Dilworth,Caroline; Gennings,Chris; Hauser, ...

P30ES023515,R01ES025214


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2016

Tel1 and Rif2 Regulate MRX Functions inEnd-Tethering and Repair of DNA Double-StrandBreaks.

Cassani, Corinne;Gobbini, Elisa; Wang,Weibin; Niu, Hengyao;Clerici, Michela; Sung,Patrick; ...

R01ES007061 PLoS Biol (2016 Feb) 26901759

2016

Tertiary Epimutations - A Novel Aspect of EpigeneticTransgenerational Inheritance Promoting Genome ...

McCarrey, John R;Lehle, Jake D; Raju,Seetha S; Wang,Yufeng; Nilsson, EricE; Skinner, Micha ...

R01ES012974,R01ES012974

PLoS One (2016) 27992467

2016

The Metacaspase (Mca1p) Restricts O-glycosylationDuring Farnesol-induced Apoptosis in Candida albic...

Léger, Thibaut; Garcia,Camille; Camadro,Jean-Michel

R01ES024478 Mol Cell Proteomics (201607)

27125826

2016

The organoarsenical biocycle and the primordialantibiotic methylarsenite.

Li, Jiaojiao; Pawitwar,Shashank S; Rosen,Barry P

R01ES023779 Metallomics (2016 10 01) 27730229

2016

Translesion synthesis of O4-alkylthymidine lesions inhuman cells.

Wu, Jun; Li, Lin; Wang,Pengcheng; You,Changjun; Williams,Nicole L; Wang,Yinsheng


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2016

Uppsala Consensus Statement on EnvironmentalContaminants and the Global Obesity Epidemic.

Lind, Lars; Lind, PMonica; Lejonklou,Margareta H; Dunder,Linda; Bergman, Åke;Guerrero-Bosag ...

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2016

Valosin-containing Protein (VCP)/p97 SegregaseMediates Proteolytic Processing of CockayneSyndrome ...

He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Sharma, Nidhi;Wani, Altaf A

R01ES012991 J Biol Chem (2016 Apr 01) 26826127

2016

Yeast DNA polymerase ζ maintains consistent activityand mutagenicity across a wide range of physiol ...

Kochenova, Olga V;Bezalel-Buch, Rachel;Tran, Phong; Makarova,Alena V; Chabes,Andrei; Burger ...


27903904

2016

ZMYND8 Reads the Dual Histone MarkH3K4me1-H3K14ac to Antagonize the Expression ofMetastasis-Linked ...

Li, Na; Li, Yuanyuan;Lv, Jie; Zheng,Xiangdong; Wen,Hong; Shen, Hongjie;Zhu, Guangjing; Ch ...

R01ES025761,R01ES025761

Mol Cell (2016 08 04) 27477906

2016

A rolling circle replication mechanism producesmultimeric lariats of mitochondrial DNA in Caenorhab...

Lewis, Samantha C;Joers, Priit; Willcox,Smaranda; Griffith,Jack D; Jacobs, HowardT; Hyman, ...

R56ES013773 PLoS Genet (2015 Feb) 25693201

2015

A simple, high-yield synthesis of DNA duplexescontaining a covalent, thermally cleavable interstran ...

Gamboa Varela,Jacqueline; Gates, KentS

R01ES021007 Angew Chem Int Ed Engl(2015 Jun 22)

25967397

2015

Anticancer therapeutic potential of Mnporphyrin/ascorbate system.

Tovmasyan, Artak;Sampaio, Romulo S;Boss, Mary-Keara;Bueno-Janice,Jacqueline C; Bader,Bader ...

R01ES023485 Free Radic Biol Med (2015Dec)

26496207

2015

AP endonuclease 1 prevents trinucleotide repeatexpansion via a novel mechanism during base excision...

Beaver, Jill M; Lai,Yanhao; Xu, Meng;Casin, Astrid H;Laverde, Eduardo E;Liu, Yuan

R01ES023569 Nucleic Acids Res (2015Jul 13)

25990721

2015

Bypass of a 5',8-cyclopurine-2'-deoxynucleoside byDNA polymerase β during DNA replication and base...

Jiang, Zhongliang; Xu,Meng; Lai, Yanhao;Laverde, Eduardo E;Terzidis, Michael A;Masi, Annal ...

R01ES023569 DNA Repair (Amst) (2015Sep)

26123757

2015

Cdt2-mediated XPG degradation promotes gap-fillingDNA synthesis in nucleotide excision repair.

Han, Chunhua; Wani,Gulzar; Zhao, Ran;Qian, Jiang; Sharma,Nidhi; He, Jinshan;Zhu, Qianzhen ...

R01ES012991 Cell Cycle (2015) 25483071

2015

Characterization of Interstrand DNA-DNACross-Links Derived from Abasic Sites UsingBacteriophage ϕ2 ...

Yang, Zhiyu; Price,Nathan E; Johnson,Kevin M; Gates, Kent S

R01ES021007 Biochemistry (2015 Jul 14) 26103998

2015

Characterization of Interstrand DNA-DNACross-Links Using the α-Hemolysin Protein Nanopore.

Zhang, Xinyue; Price,Nathan E; Fang, Xi;Yang, Zhiyu; Gu,Li-Qun; Gates, Kent S

R01ES021007 ACS Nano (2015 Dec 22) 26563913

2015

Chemical and structural characterization of interstrandcross-links formed between abasic sites and ...

Price, Nathan E;Catalano, Michael J;Liu, Shuo; Wang,Yinsheng; Gates, KentS


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2015

Chemical structure and properties of interstrandcross-links formed by reaction of guanine residues ...

Catalano, Michael J;Liu, Shuo; Andersen,Nisana; Yang, Zhiyu;Johnson, Kevin M;Price, Nathan ...

R01ES021007 J Am Chem Soc (2015Mar 25)

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2015

ChIP-Seq analysis of the adult male mouse brain afterdevelopmental exposure to arsenic.

Tyler, Christina R;Weber, Jessica A;Labrecque, Matthew;Hessinger, Justin M;Edwards, Jeremy ...

R01ES019583 Data Brief (2015 Dec) 26543888

2015

Colon cancer-associated mutator DNA polymerase δvariant causes expansion of dNTP pools increasing i ...

Mertz, Tony M;Sharma, Sushma;Chabes, Andrei;Shcherbakova, Polina V

R01ES015869 Proc Natl Acad Sci U S A(2015 May 12)

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2015

Cytotoxic and mutagenic properties ofO4-alkylthymidine lesions in Escherichia coli cells.

Wang, Pengcheng;Amato, Nicholas J;Zhai, Qianqian; Wang,Yinsheng

R01ES025121 Nucleic Acids Res (2015Dec 15)

26400162

2015

Damaged DNA-binding protein down-regulatesepigenetic mark H3K56Ac through histone deacetylase1 and ...

Zhu, Qianzheng; Battu,Aruna; Ray, Alo; Wani,Gulzar; Qian, Jiang; He,Jinshan; Wang, Qi-en;...

R01ES012991 Mutat Res (2015 Jun) 26255936

2015

Developmental exposure to 50 parts-per-billion arsenicinfluences histone modifications and associat ...

Tyler, Christina R;Hafez, Alexander K;Solomon, Elizabeth R;Allan, Andrea M

R01ES019583 Toxicol Appl Pharmacol(2015 Oct 01)

26193056

2015

Distinct actions of ancestral vinclozolin and juvenilestress on neural gene expression in the male ...

Gillette, Ross;Miller-Crews, Isaac;Skinner, Michael K;Crews, David

R01ES012974,R01ES012974

Front Genet (2015) 25784924

2015

Disturbed flow induces systemic changes inmetabolites in mouse plasma: a metabolomics studyusing A ...

Go, Young-Mi; Kim,Chan Woo; Walker,Douglas I; Kang, DongWon; Kumar, Sandeep;Orr, Michael; ...

R01ES023485 Am J Physiol Regul IntegrComp Physiol (2015 Jan01)

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2015

DNA double-strand breaks by Cr(VI) are targeted toeuchromatin and cause ATR-dependent phosphorylati...

DeLoughery, Zachary;Luczak, Michal W;Ortega-Atienza, Sara;Zhitkovich, Anatoly

R01ES008786 Toxicol Sci (2015 Jan) 25288669

2015

DNA polymerase ζ-dependent lesion bypass inSaccharomyces cerevisiae is accompanied byerror-prone c ...

Kochenova, Olga V;Daee, Danielle L;Mertz, Tony M;Shcherbakova, Polina V

R01ES015869 PLoS Genet (2015 Mar) 25826305

2015

DNA replication stress underlies renal phenotypes inCEP290-associated Joubert syndrome.

Slaats, Gisela G;Saldivar, Joshua C;Bacal, Julien; Zeman,Michelle K; Kile,Andrew C; Hynes, ...

R01ES016486 J Clin Invest (2015 Sep) 26301811

2015

DNA sequence alignment by microhomology samplingduring homologous recombination.

Qi, Zhi; Redding, Sy;Lee, Ja Yil; Gibb,Bryan; Kwon,YoungHo; Niu,Hengyao; Gaines,William ...

R01ES007061 Cell (2015 Feb 26) 25684365

2015

DNA-Protein Cross-Links: Formation, StructuralIdentities, and Biological Outcomes.

Tretyakova, Natalia Y;Groehler 4th, Arnold;Ji, Shaofei

R01ES023350 Acc Chem Res (2015 Jun16)

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2015

Early programing of uterine tissue by bisphenol A:Critical evaluation of evidence from animal expos ...

Suvorov, Alexander;Waxman, David J

R01ES024421 Reprod Toxicol (2015Nov)

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2015

Environmental Epigenetics and a Unified Theory ofthe Molecular Aspects of Evolution: A Neo-Lamarcki...


Genome Biol Evol (2015May)

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2015

Environmentally Induced EpigeneticTransgenerational Inheritance of Altered SRYGenomic Binding Duri ...

Skinner, Michael K;Bhandari, Ramji K;Haque, M Muksitul;Nilsson, Eric E

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Environ Epigenet (2015Dec)

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Environmentally induced epigenetic transgenerationalinheritance of disease susceptibility.

Nilsson, Eric E;Skinner, Michael K

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Transl Res (2015 Jan) 24657180

2015

Environmentally Induced EpigeneticTransgenerational Inheritance of ReproductiveDisease.


R01ES012974,R01ES012974

Biol Reprod (2015 Dec) 26510870

2015

Environmentally induced epigenetic transgenerationalinheritance of sperm epimutations promote genet ...

Skinner, Michael K;Guerrero-Bosagna,Carlos; Haque, MMuksitul

R01ES012974,R01ES012974

Epigenetics (2015) 26237076

2015

Error-prone translesion synthesis past DNA-peptidecross-links conjugated to the major groove of DNA ...

Wickramaratne, Susith;Boldry, Emily J;Buehler, Charles;Wang, Yen-Chih;Distefano, Mark D; Tr...

R01ES023350 J Biol Chem (2015 Jan 9) 25391658

2015

Functions and regulation of the multitasking FANCMfamily of DNA motor proteins.

Xue, Xiaoyu; Sung,Patrick; Zhao, Xiaolan

R01ES007061 Genes Dev (2015 Sep 01) 26341555

2015

Genome-Wide Locations of Potential EpimutationsAssociated with Environmentally Induced EpigeneticT ...

Haque, M Muksitul;Holder, Lawrence B;Skinner, Michael K

R01ES012974,R01ES012974

PLoS One (2015) 26571271

2015

Genome-Wide Profiling of PARP1 Reveals anInterplay with Gene Regulatory Regions and DNAMethylation ...

Nalabothula,Narasimharao;Al-jumaily, Taha;Eteleeb, Abdallah M;Flight, Robert M;Xiaorong, S ...

R01ES024478 PLoS One (2015) 26305327

2015

Heterozygosity for a hypomorphic Polβ mutationreduces the expansion frequency in a mouse model of t...

Lokanga, Rachel Adihe;Senejani, AlirezaGhodsi; Sweasy, JoannBalazs; Usdin, Karen

R01ES019179 PLoS Genet (2015 Apr) 25886163

2015

High-throughput screening-compatible assays ofAs(III) S-adenosylmethionine methyltransferase activi...

Dong, Hui; Xu,Wenzhong; Pillai,Jitesh K; Packianathan,Charles; Rosen, Barry P

R01ES023779 Anal Biochem (2015 Jul01)

25866076

2015

HLTF's Ancient HIRAN Domain Binds 3' DNA Endsto Drive Replication Fork Reversal.

Kile, Andrew C;Chavez, Diana A;Bacal, Julien; Eldirany,Sherif; Korzhnev,Dmitry M; Bezsonova...

R01ES016486 Mol Cell (2015 Jun 18) 26051180

2015

Human DNA ligase III bridges two DNA ends topromote specific intermolecular DNA end joining.

Kukshal, Vandna; Kim,In-Kwon; Hura,Gregory L; Tomkinson,Alan E; Tainer, John A;Ellenberger, ...

R01ES012512 Nucleic Acids Res (2015Aug 18)

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2015

Identification of Small Molecule Inhibitors of HumanAs(III) S-Adenosylmethionine Methyltransferase ...

Dong, Hui;Madegowda, Mahendra;Nefzi, Adel; Houghten,Richard A; Giulianotti,Marc A; Rosen, ...


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Inorganic Arsenic-induced cellular transformation iscoupled with genome wide changes in chromatin s ...

Riedmann, Caitlyn; Ma,Ye; Melikishvili,Manana; Godfrey,Steven Grason; Zhang,Zhou; Chen, Ku ...

R01ES024478 BMC Genomics (2015) 25879800

2015

Linker histone H1 and H3K56 acetylation areantagonistic regulators of nucleosome dynamics.

Bernier, Morgan; Luo,Yi; Nwokelo, KingsleyC; Goodwin, Michelle;Dreher, Sarah J; Zhang,Pei; ...

R01ES024478 Nat Commun (2015) 26648124

2015

LKB1 preserves genome integrity by stimulatingBRCA1 expression.

Gupta, Romi; Liu, AlexY; Glazer, Peter M;Wajapeyee, Narendra

R01ES005775 Nucleic Acids Res (2015Jan)

25488815

2015

Low-Dose Cadmium Causes Metabolic and GeneticDysregulation Associated With Fatty Liver Disease inM ...

Go, Young-Mi; Sutliff,Roy L; Chandler,Joshua D; Khalidur,Rahman; Kang,Bum-Yong; Anania, Fr...

P30ES019776,R01ES023485,T32ES012870

Toxicol Sci (2015 Oct) 26187450

2015

Markov counting models for correlated binaryresponses.

Crawford, Forrest W;Zelterman, Daniel

R01ES005775 Biostatistics (2015 Jul) 25792624

2015

Mass spectrometry for the assessment of theoccurrence and biological consequences of DNAadducts.

Liu, Shuo; Wang,Yinsheng

R01ES021007 Chem Soc Rev (2015 Nov7)

26204249

2015

Mechanism of action studies of lomaiviticin A and themonomeric lomaiviticin aglycon. Selective and ...

Colis, Laureen C;Hegan, Denise C;Kaneko, Miho; Glazer,Peter M; Herzon, SethB

R01ES005775 J Am Chem Soc (2015May 6)

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2015

Metabolic Characterization of the Common Marmoset(Callithrix jacchus).

Go, Young-Mi; Liang,Yongliang; Uppal,Karan; Soltow, QuinlynA; Promislow, Daniel EL; Wachtma ...

P30ES019776,R01ES023485,T32ES012870

PLoS One (2015) 26581102

2015

Metabolome-wide association study of phenylalaninein plasma of common marmosets.

Go, Young-Mi; Walker,Douglas I; Soltow,Quinlyn A; Uppal,Karan; Wachtman,Lynn M; Strobel, F ...

P30ES019776,R01ES023485,T32ES012870

Amino Acids (2015 Mar) 25526869

2015

Metabolome-Wide Association Study of Primary OpenAngle Glaucoma.

Burgess, L Goodwin;Uppal, Karan; Walker,Douglas I; Roberson,Rachel M; Tran,ViLinh; Parks, ...

P30ES019776,R01ES023485,T32ES012870

Invest Ophthalmol Vis Sci(2015 Jul)

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2015

MicroRNA silencing for cancer therapy targeted to thetumour microenvironment.

Cheng, Christopher J;Bahal, Raman; Babar,Imran A; Pincus,Zachary; Barrera,Francisco; Liu, ...

R01ES005775 Nature (2015 Feb 5) 25409146

2015

Mimicking Ribosomal Unfolding of RNA Pseudoknotin a Protein Channel.

Zhang, Xinyue; Xu,Xiaojun; Yang, Zhiyu;Burcke, Andrew J;Gates, Kent S; Chen,Shi-Jie; Gu, ...

R01ES021007 J Am Chem Soc (2015Dec 23)

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Mitochondrial Single-stranded DNA-binding ProteinsStimulate the Activity of DNA Polymerase γ by Org ...

Ciesielski, Grzegorz L;Bermek, Oya;Rosado-Ruiz, FernandoA; Hovde, Stacy L;Neitzke, Orrin J; ...

R56ES013773 J Biol Chem (2015 Nov27)

26446790

2015

Multifaceted control of DNA repair pathways by thehypoxic tumor microenvironment.

Scanlon, Susan E;Glazer, Peter M

R01ES005775 DNA Repair (Amst) (2015Aug)

25956861

2015

Obesity, diabetes, and associated costs of exposure toendocrine-disrupting chemicals in the Europea ...

Legler, Juliette;Fletcher, Tony;Govarts, Eva; Porta,Miquel; Blumberg,Bruce; Heindel, Jerro ...

R01ES023316,R01ES023316

J Clin Endocrinol Metab(2015 Apr)

25742518

2015

Origin and development of neuropil glia of theDrosophila larval and adult brain: Two distinct glial ...

Omoto, Jaison Jiro;Yogi, Puja; Hartenstein,Volker

R01ES029357 Dev Biol (2015 Aug 15) 25779704

2015

Parma consensus statement on metabolic disruptors. Heindel, Jerrold J; VomSaal, Frederick S;Blumberg, Bruce;Bovolin, Patrizia;Calamandrei, Gem ...

R01ES023316,R01ES023316


26092037

2015

Prenatal arsenic exposure alters the programming ofthe glucocorticoid signaling system during embry ...

Caldwell, Katharine E;Labrecque, Matthew T;Solomon, Benjamin R;Ali, Abdulmehdi; Allan,Andre ...

R01ES019583 Neurotoxicol Teratol (2015Jan-Feb)

25459689

2015

Promotion of BRCA2-Dependent HomologousRecombination by DSS1 via RPA Targeting and DNAMimicry.

Zhao, Weixing;Vaithiyalingam,Sivaraja; San Filippo,Joseph; Maranon, DavidG; Jimenez-Sainz, ...

R01ES007061 Mol Cell (2015 Jul 16) 26145171

2015

Promotion of presynaptic filament assembly by theensemble of S. cerevisiae Rad51 paralogues with Ra ...

Gaines, William A;Godin, Stephen K;Kabbinavar, Faiz F;Rao, Timsi;VanDemark, Andrew P;Sung, ...

R01ES007061 Nat Commun (2015) 26215801

2015

Quantitative measurement of transcriptional inhibitionand mutagenesis induced by site-specifically ...

You, Changjun; Wang,Yinsheng

R01ES025121 Nat Protoc (2015 Sep) 26292071

2015

Redox theory of aging. Jones, Dean P P30ES019776,R01ES023485,T32ES012870

Redox Biol (2015 Aug) 25863726

2015

Reference Standardization for Mass Spectrometry andHigh-resolution Metabolomics Applications to Exp ...

Go, Young-Mi; Walker,Douglas I; Liang,Yongliang; Uppal,Karan; Soltow, QuinlynA; Tran, ViLi ...

P30ES019776,R01ES023485,T32ES012870

Toxicol Sci (2015 Dec) 26358001

2015

Resveratrol protects against arsenic trioxide-inducedoxidative damage through maintenance of glutat ...

Chen, Chengzhi; Jiang,Xuejun; Lai, Yanhao;Liu, Yuan; Zhang,Zunzhen

R01ES023569 Environ Mol Mutagen(2015 Apr)

25339131

2015

Rev1 promotes replication through UV lesions inconjunction with DNA polymerases η, ι, and κ but not...

Yoon, Jung-Hoon; Park,Jeseong; Conde, Juan;Wakamiya, Maki;Prakash, Louise;Prakash, Satya

R01ES022948 Genes Dev (2015 Dec 15) 26680302

2015

Role of mismatch repair proteins in the processing ofcisplatin interstrand cross-links.

Sawant, Akshada;Kothandapani,Anbarasi; Zhitkovich,Anatoly; Sobol, RobertW; Patrick, Steve M

R01ES008786 DNA Repair (Amst) (2015Nov)

26519826

2015

Selective modulation of the functions of a conservedDNA motor by a histone fold complex.

Xue, Xiaoyu; Choi,Koyi; Bonner, Jaclyn N;Szakal, Barnabas; Chen,Yu-Hung; Papusha,Alma; Sar ...

R01ES007061 Genes Dev (2015 May 15) 25956905

2015

Sex-Dependent effects of developmental arsenicexposure on methylation capacity and methylation regu...

Allan, Andrea M;Hafez, Alexander K;Labrecque, Matthew T;Solomon, Elizabeth R;Shaikh, M Nabi ...

R01ES019583 Toxicol Rep (2015 Oct) 26855884

2015

Significance of ligand interactions involvingHop2-Mnd1 and the RAD51 and DMC1 recombinasesin homol ...

Zhao, Weixing; Sung,Patrick


25820426

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Synthesis of DNA Oligodeoxynucleotides ContainingSite-Specific 1,3-Butadiene-Deoxyadenosine Lesions...

Wickramaratne, Susith;Seiler, Christopher L;Tretyakova, Natalia Y

R01ES023350 Curr Protoc Nucleic AcidChem (2015 Jun 03)

26344227

2015

Synthetic viability genomic screening defines Sae2function in DNA repair.

Puddu, Fabio;Oelschlaegel, Tobias;Guerini, Ilaria; Geisler,Nicola J; Niu, Hengyao;Herzog, ...

R01ES007061 EMBO J (2015 Jun 03) 25899817

2015

The cysteine proteome. Go, Young-Mi;Chandler, Joshua D;Jones, Dean P

P30ES019776,R01ES023485,T32ES012870

Free Radic Biol Med (2015Jul)

25843657

2015

The Redox Code. Jones, Dean P; Sies,Helmut

P30ES019776,R01ES023485,T32ES012870

Antioxid Redox Signal(2015 Sep 20)

25891126

2015

Tumor suppressor p53 stole the AKT in hypoxia. Yun, Zhong; Glazer,Peter M

R01ES005775 J Clin Invest (2015 Jun) 25961449

2015

USP7 deubiquitinase promotes ubiquitin-dependentDNA damage signaling by stabilizing RNF168.

Zhu, Qianzheng;Sharma, Nidhi; He,Jinshan; Wani, Gulzar;Wani, Altaf A

R01ES012991 Cell Cycle (2015) 25894431

2015

USP7 modulates UV-induced PCNAmonoubiquitination by regulating DNA polymeraseeta stability.

Qian, J; Pentz, K; Zhu,Q; Wang, Q; He, J;Srivastava, A K; Wani,A A

R01ES012991 Oncogene (2015 Sep 03) 25435364

2015

A 5', 8-cyclo-2'-deoxypurine lesion inducestrinucleotide repeat deletion via a unique lesion bypass...

Xu, Meng; Lai, Yanhao;Jiang, Zhongliang;Terzidis, Michael A;Masi, Annalisa;Chatgilialoglu, ...


25428354

2014

A common cancer-associated DNA polymerase εmutation causes an exceptionally strong mutatorphenotyp ...

Kane, Daniel P;Shcherbakova, Polina V

R01ES015869 Cancer Res (2014 Apr 1) 24525744

2014

A new kind of inheritance. Skinner, Michael K R01ES012974,R01ES012974

Sci Am (2014 Aug) 25095468

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A recombinant reporter system for monitoringreactivation of an endogenously DNAhypermethylated gen ...

Cui, Ying; Hausheer,Frederick; Beaty,Robert; Zahnow,Cynthia; Issa, JeanPierre; Bunz, Frede ...

R01ES011858 Cancer Res (2014 Jul 15) 24876104

2014

Amplified single base-pair mismatch detection viaaggregation of exonuclease-sheared gold nanopartic ...

Wu, Shuo; Liang,Pingping; Yu, Haixiang;Xu, Xiaowen; Liu,Yuan; Lou, Xinhui;Xiao, Yi

R01ES023569 Anal Chem (2014 Apr 1) 24611947

2014

Avoidance of ribonucleotide-induced mutations byRNase H2 and Srs2-Exo1 mechanisms.

Potenski, Catherine J;Niu, Hengyao; Sung,Patrick; Klein, HannahL

R01ES007061 Nature (2014 Jul 10) 24896181

2014

Base excision repair of chemotherapeutically-inducedalkylated DNA damage predominantly causes contr ...

Lai, Yanhao; Beaver,Jill M; Lorente, Karla;Melo, Jonathan;Ramjagsingh, Shyama;Agoulnik, Ir ...

R01ES023569 PLoS One (2014) 24691413

2014

Base excision repair of oxidative DNA damagecoupled with removal of a CAG repeat hairpinattenuates ...

Xu, Meng; Lai, Yanhao;Torner, Justin; Zhang,Yanbin; Zhang,Zunzhen; Liu, Yuan

R01ES023569 Nucleic Acids Res (2014Apr)

24423876

2014

Cancer epigenetics: tumor heterogeneity, plasticity ofstem-like states, and drug resistance.

Easwaran, Hariharan;Tsai, Hsing-Chen;Baylin, Stephen B

R01ES011858 Mol Cell (2014 Jun 5) 24905005

2014

Causes and consequences of replication stress. Zeman, Michelle K;Cimprich, Karlene A

R01ES016486 Nat Cell Biol (2014 Jan) 24366029

2014

Chromosomal translocations in human cells aregenerated by canonical nonhomologous end-joining.

Ghezraoui, Hind;Piganeau, Marion;Renouf, Benjamin;Renaud, Jean-Baptiste;Sallmyr, Annahita; ...

R01ES012512 Mol Cell (2014 Sep 18) 25201414

2014

Concentration-dependent exchange of replicationprotein A on single-stranded DNA revealed by single-...

Gibb, Bryan; Ye, LingF; Gergoudis, StephanieC; Kwon, YoungHo;Niu, Hengyao; Sung,Patrick; G ...

R01ES007061 PLoS One (2014) 24498402

2014

Conditional inactivation of Miwi2 reveals that MIWI2is only essential for prospermatogonial develop ...

Bao, J; Zhang, Y;Schuster, A S;Ortogero, N; Nilsson, EE; Skinner, M K; Yan,W

R01ES012974,R01ES012974

Cell Death Differ (2014May)

24464225

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Covalent adduct formation between theantihypertensive drug hydralazine and abasic sites indouble- ...

Melton, Douglas;Lewis, Calvin D; Price,Nathan E; Gates, Kent S


25405892

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Cytokine (IL16) and tyrphostin actions on ovarianprimordial follicle development.

Feeney, Amanda;Nilsson, Eric; Skinner,Michael K

R01ES012974,R01ES012974

Reproduction (2014 Sep) 24970835

2014

DDT, epigenetic harm, and transgenerationalenvironmental justice.

Kabasenche, William P;Skinner, Michael K

R01ES012974,R01ES012974

Environ Health (2014 Aug02)

25086599

2014

Disturbed flow enhances inflammatory signaling andatherogenesis by increasing thioredoxin-1 level i ...

Go, Young-Mi; Son,Dong Ju; Park,Heonyong; Orr,Michael; Hao, Li;Takabe, Wakako;Kumar, San ...

R01ES023485 PLoS One (2014) 25265386

2014

DNA damage-binding complex recruits HDAC1 torepress Bcl-2 transcription in human ovarian cancercel ...

Zhao, Ran; Han,Chunhua; Eisenhauer,Eric; Kroger, John;Zhao, Weiqiang; Yu,Jianhua; Selvendi ...

R01ES012991 Mol Cancer Res (2014Mar)

24249678

2014

DNA damage-specific deubiquitination regulatesRad18 functions to suppress mutagenesis.

Zeman, Michelle K;Lin, Jia-Ren; Freire,Raimundo; Cimprich,Karlene A

R01ES016486 J Cell Biol (2014 Jul 21) 25023518

2014

DNA polymerases ζ and Rev1 mediate error-pronebypass of non-B DNA structures.

Northam, Matthew R;Moore, Elizabeth A;Mertz, Tony M; Binz,Sara K; Stith, Carrie M;Stepchenk ...


24049079

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Down-regulation of Rad51 activity during meiosis inyeast prevents competition with Dmc1 for repair ...

Liu, Yan; Gaines,William A; Callender,Tracy; Busygina,Valeria; Oke, Ashwini;Sung, Patrick; ...

R01ES007061 PLoS Genet (2014 Jan) 24465215

2014

Earth Abides Arsenic Biotransformations. Zhu, Yong-Guan;Yoshinaga, Masafumi;Zhao, Fang-Jie; Rosen,Barry P

R01ES023779 Annu Rev Earth Planet Sci(2014 May 01)

26778863

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Endocrine disruptor induction of epigenetictransgenerational inheritance of disease.


Mol Cell Endocrinol (2014Dec)

25088466

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Environment, epigenetics and reproduction. Skinner, Michael K R01ES012974,R01ES012974


25086400

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Environmental epigenetics andphytoestrogen/phytochemical exposures.

Guerrero-Bosagna,Carlos M; Skinner,Michael K

R01ES012974,R01ES012974

J Steroid Biochem MolBiol (2014 Jan)

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Environmental stress and epigenetic transgenerationalinheritance.


BMC Med (2014 Sep 05) 25259699

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Environmentally induced epigenetic transgenerationalinheritance of male infertility.

Guerrero-Bosagna,Carlos; Skinner,Michael K

R01ES012974,R01ES012974

Curr Opin Genet Dev(2014 Jun)

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2014

Epigenetics and the evolution of Darwin's Finches. Skinner, Michael K;Gurerrero-Bosagna,Carlos; Haque, MMuksitul; Nilsson, EricE; Koop, Jennif ...

R01ES012974,R01ES012974

Genome Biol Evol (2014Aug)

25062919

2014

Expression of the p12 subunit of human DNApolymerase δ (Pol δ), CDK inhibitor p21(WAF1),Cdt1, cycl ...

Zhao, Hong; Zhang,Sufang; Xu, Dazhong;Lee, Marietta Ywt;Zhang, Zhongtao; Lee,Ernest Yc; Da ...

R56ES014737 Cell Cycle (2014) 25483089

2014

Fluoxetine treatment ameliorates depression inducedby perinatal arsenic exposure via a neurogenic m ...

Tyler, Christina R;Solomon, Benjamin R;Ulibarri, Adam L;Allan, Andrea M

R01ES019583 Neurotoxicology (2014Sep)

24952232

2014

Gene bionetworks involved in the epigenetictransgenerational inheritance of altered matepreference ...

Skinner, Michael K;Savenkova, Marina I;Zhang, Bin; Gore,Andrea C; Crews,David

R01ES012974,R01ES012974

BMC Genomics (2014) 24885959

2014

Harnessing the potential of epigenetic therapy to targetsolid tumors.

Ahuja, Nita; Easwaran,Hariharan; Baylin,Stephen B

R01ES011858 J Clin Invest (2014 Jan) 24382390

2014

Hypoxic stress facilitates acute activation and chronicdownregulation of fanconi anemia proteins.

Scanlon, Susan E;Glazer, Peter M

R01ES005775 Mol Cancer Res (2014 Jul) 24688021

2014

Identification of genomic features in environmentallyinduced epigenetic transgenerational inherited ...

Guerrero-Bosagna,Carlos; Weeks, Shelby;Skinner, Michael K

R01ES012974,R01ES012974

PLoS One (2014) 24937757

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Imbalanced class learning in epigenetics. Haque, M Muksitul;Skinner, Michael K;Holder, Lawrence B

R01ES012974,R01ES012974

J Comput Biol (2014 Jul) 24798423

2014

Interplay between DNA repair and inflammation, andthe link to cancer.

Kidane, Dawit; Chae,Wook Jin; Czochor,Jennifer; Eckert, KristinA; Glazer, Peter M;Bothwell, ...

R01ES019179 Crit Rev Biochem MolBiol (2014 Mar-Apr)

24410153

2014

Interstrand DNA-DNA cross-link formation betweenadenine residues and abasic sites in duplex DNA.

Price, Nathan E;Johnson, Kevin M;Wang, Jin; Fekry,Mostafa I; Wang,Yinsheng; Gates, KentS

R01ES021007 J Am Chem Soc (2014Mar 5)

24506784

2014

Mechanistic insights into the role of Hop2-Mnd1 inmeiotic homologous DNA pairing.

Zhao, Weixing; Saro,Dorina; Hammel,Michal; Kwon,Youngho; Xu,Yuanyuan; Rambo,Robert P; Wil ...


24150939

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Mitochondrial metabolomics using high-resolutionFourier-transform mass spectrometry.

Go, Young-Mi; Uppal,Karan; Walker, DouglasI; Tran, ViLinh; Dury,Lauriane; Strobel,Frederic ...

R01ES023485,T32ES012870


2014

Monitoring Cr intermediates and reactive oxygenspecies with fluorescent probes during chromate redu...

DeLoughery, Zachary;Luczak, Michal W;Zhitkovich, Anatoly

R01ES008786 Chem Res Toxicol (2014May 19)

24646070

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Mutation of POLB causes lupus in mice. Senejani, Alireza G;Liu, Yanfeng; Kidane,Dawit; Maher, StephenE; Zeiss, Caroline J;Park, H ...

R01ES019179 Cell Rep (2014 Jan 16) 24388753

2014

Nature, nurture and epigenetics. Crews, David; Gillette,Ross; Miller-Crews,Isaac; Gore, Andrea C;Skinner, Michael K

R01ES012974,R01ES012974


25102229

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Pathway of human AS3MT arsenic methylation. Dheeman, DharmendraS; Packianathan,Charles; Pillai, Jitesh K;Rosen, Barry P

R01ES023779 Chem Res Toxicol (2014Nov 17)

25325836

2014

Pesticide methoxychlor promotes the epigenetictransgenerational inheritance of adult-onset disease ...

Manikkam, Mohan;Haque, M Muksitul;Guerrero-Bosagna,Carlos; Nilsson, Eric E;Skinner, Michael ...

R01ES012974,R01ES012974

PLoS One (2014) 25057798

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Protein dynamics during presynaptic-complexassembly on individual single-stranded DNAmolecules.

Gibb, Bryan; Ye, LingF; Kwon, YoungHo;Niu, Hengyao; Sung,Patrick; Greene, Eric C

R01ES007061 Nat Struct Mol Biol (2014Oct)

25195049

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Replicative bypass of abasic site in Escherichia coliand human cells: similarities and differences.

Weerasooriya, Savithri;Jasti, Vijay P; Basu,Ashis K

R01ES021762,R01ES023350

PLoS One (2014) 25226389

2014

Response to the letter to the editor regarding our article(Dheeman et al., 2014).

Dheeman, DharmendraS; Packianathana,Charles; Pillai, Jitesh K;Rosen, Barry P


25383697

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Restriction of replication fork regression activities by aconserved SMC complex.

Xue, Xiaoyu; Choi,Koyi; Bonner, Jaclyn;Chiba, Tamara; Kwon,Youngho; Xu,Yuanyuan; Sanchez, ...

R01ES007061 Mol Cell (2014 Nov 6) 25439736

2014

Role of CpG deserts in the epigenetic transgenerationalinheritance of differential DNA methylation ...

Skinner, Michael K;Guerrero-Bosagna,Carlos

R01ES012974,R01ES012974

BMC Genomics (2014) 25142051

2014

Roles of Gremlin 1 and Gremlin 2 in regulatingovarian primordial to primary follicle transition.

Nilsson, Eric E; Larsen,Ginger; Skinner,Michael K

R01ES012974,R01ES012974

Reproduction (2014 Jun) 24614542

2014

Sexually dimorphic effects of ancestral exposure tovinclozolin on stress reactivity in rats.

Gillette, Ross;Miller-Crews, Isaac;Nilsson, Eric E;Skinner, Michael K;Gore, Andrea C; Crews...

R01ES012974,R01ES012974

Endocrinology (2014 Oct) 25051444

2014

Silencing of the DNA mismatch repair gene MLH1induced by hypoxic stress in a pathway dependent on t...

Lu, Yuhong;Wajapeyee, Narendra;Turker, Mitchell S;Glazer, Peter M

R01ES005775 Cell Rep (2014 Jul 24) 25043185

2014

Structural and functional conservation of fungal MatAand human SRY sex-determining proteins.

Czaja, Wioletta; Miller,Karen Y; Skinner,Michael K; Miller,Bruce L

R01ES012974,R01ES012974

Nat Commun (2014) 25399555

2014

Syntheses and characterizations of the in vivoreplicative bypass and mutagenic properties of the mi...

Zhai, Qianqian; Wang,Pengcheng; Cai, Qian;Wang, Yinsheng

R01ES025121 Nucleic Acids Res (2014) 25120272

2014

The cytotoxicity of (-)-lomaiviticin A arises frominduction of double-strand breaks in DNA.

Colis, Laureen C; Woo,Christina M; Hegan,Denise C; Li, Zhenwu;Glazer, Peter M;Herzon, Seth ...

R01ES005775 Nat Chem (2014 Jun) 24848236

2014

The Effects of Arsenic Exposure on Neurological andCognitive Dysfunction in Human and Rodent Studie ...

Tyler, Christina R;Allan, Andrea M

R01ES019583 Curr Environ Health Rep(2014)

24860722

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The NuRD complex cooperates with DNMTs tomaintain silencing of key colorectal tumor suppressorgene ...

Cai, Y; Geutjes, E-J; deLint, K; Roepman, P;Bruurs, L; Yu, L-R;Wang, W; vanBlijswijk, J; ...

R01ES011858 Oncogene (2014 Apr 24) 23708667

2014

The S229L colon tumor-associated variant of DNApolymerase β induces cellular transformation as a re ...

Nemec, Antonia A;Murphy, Drew L;Donigan, Katherine A;Sweasy, Joann B

R01ES019179 J Biol Chem (2014 May16)

24668809

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The tail that wags the dog: p12, the smallest subunit ofDNA polymerase δ, is degraded by ubiquitin ...

Lee, Marietta Y W T;Zhang, Sufang; Lin, SzuHua Sharon; Wang,Xiaoxiao;Darzynkiewicz, Zbignie...

R56ES014737 Cell Cycle (2014) 24300032

2014

Toward hypoxia-selective DNA-alkylating agents builtby grafting nitrogen mustards onto the bioreduc ...

Johnson, Kevin M;Parsons, Zachary D;Barnes, Charles L;Gates, Kent S

R01ES021007 J Org Chem (2014 Aug 15) 25029663

2014

Transcriptional bypass of regioisomeric ethylatedthymidine lesions by T7 RNA polymerase and humanR ...

You, Changjun; Wang,Pengcheng; Dai,Xiaoxia; Wang,Yinsheng


25404131

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Transcriptome-metabolome wide association study(TMWAS) of maneb and paraquat neurotoxicityreveals ...

Roede, James R; Uppal,Karan; Park, Youngja;Tran, ViLinh; Jones,Dean P

P30ES019776,R01ES023485

Toxicol Rep (2014) 27722094

2014

Transgenerational effects of obesogens and the obesityepidemic.

Chamorro-García,Raquel; Blumberg,Bruce

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Curr Opin Pharmacol(2014 Dec)

25460228

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Transgenerational inheritance of prenatal obesogenexposure.

Janesick, Amanda S;Shioda, Toshihiro;Blumberg, Bruce

R01ES023316,R01ES023316


25218215

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Ubiquitin-specific protease 7 regulates nucleotideexcision repair through deubiquitinating XPC prot ...

He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Sharma, Nidhi;Han, Chunhua; Qian,Jiang; Pentz, K ...

R01ES012991 J Biol Chem (2014 Sep 26) 25118285

2014

USP3 counteracts RNF168 via deubiquitinating H2Aand γH2AX at lysine 13 and 15.

Sharma, Nidhi; Zhu,Qianzheng; Wani,Gulzar; He, Jingshan;Wang, Qi-en; Wani,Altaf A

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2014

A quantitative mass spectrometry-based approach forassessing the repair of 8-methoxypsoralen-induce ...

Liu, Shuo; Wang,Yinsheng

R01ES021007 Anal Chem (2013 Jul 16) 23789926

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A reversible histone H3 acetylation cooperates withmismatch repair and replicative polymerases in m ...

Kadyrova, Lyudmila Y;Mertz, Tony M; Zhang,Yu; Northam, MatthewR; Sheng, Ziwei;Lobachev, Ki ...

R01ES015869 PLoS Genet (2013 Oct) 24204308

2013

A role for the MRN complex in ATR activation viaTOPBP1 recruitment.

Duursma, Anja M;Driscoll, Robert; Elias,Josh E; Cimprich,Karlene A

R01ES016486 Mol Cell (2013 Apr 11) 23582259

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Adult hippocampal neurogenesis and mRNAexpression are altered by perinatal arsenic exposure inmice ...

Tyler, Christina R;Allan, Andrea M

R01ES019583 PLoS One (2013) 24019935

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ATR phosphorylates SMARCAL1 to preventreplication fork collapse.

Couch, Frank B;Bansbach, Carol E;Driscoll, Robert;Luzwick, Jessica W;Glick, Gloria G; Bétou...

R01ES016486,T32ES007028

Genes Dev (2013 Jul 15) 23873943

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Caspase-2 short isoform interacts withmembrane-associated cytoskeleton proteins to inhibitapoptosi ...

Han, Chunhua; Zhao,Ran; Kroger, John; Qu,Meihua; Wani, Altaf A;Wang, Qi-En

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Cellular roles of DNA polymerase beta. Ray, Sreerupa;Menezes, Miriam Rose;Senejani, Alireza;Sweasy, Joann B

R01ES019179 Yale J Biol Med (2013Dec 13)

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Chromium(VI) causes interstrand DNA cross-linkingin vitro but shows no hypersensitivity in cross-li ...

Morse, Jessica L;Luczak, Michal W;Zhitkovich, Anatoly

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Cognitive function and breast cancer: promise andpotential insights from functional brain imaging.

Reuter-Lorenz, PatriciaA; Cimprich, Bernadine

R01ES016486 Breast Cancer Res Treat(2013 Jan)

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DNA ligases as therapeutic targets. Tomkinson, Alan E;Howes, Timothy R L;Wiest, Nathaniel E

R01ES012512 Transl Cancer Res (2013Jun)

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Dynamics of enzymatic interactions during short flaphuman Okazaki fragment processing by two forms ...

Lin, Szu Hua Sharon;Wang, Xiaoxiao;Zhang, Sufang; Zhang,Zhongtao; Lee, ErnestY C; Lee, Mar ...

R56ES014737 DNA Repair (Amst) (2013Nov)

24035200

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Epigenetic abnormalities in cancer find a "home on therange".

Easwaran, Hariharan;Baylin, Stephen B

R01ES011858 Cancer Cell (2013 Jan 14) 23328477

2013

Functional attributes of the Saccharomyces cerevisiaemeiotic recombinase Dmc1.

Busygina, Valeria;Gaines, William A; Xu,Yuanyuan; Kwon,Youngho; Williams,Gareth J; Lin, Sh ...

R01ES007061 DNA Repair (Amst) (2013Sep)

23769192

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Hydrocarbons (jet fuel JP-8) induce epigenetictransgenerational inheritance of obesity, reproductiv ...

Tracey, Rebecca;Manikkam, Mohan;Guerrero-Bosagna,Carlos; Skinner,Michael K

R01ES012974,R01ES012974

Reprod Toxicol (2013 Apr) 23453003

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Hypoxia and DNA repair. Glazer, Peter M; Hegan,Denise C; Lu, Yuhong;Czochor, Jennifer;Scanlon, Susan E

R01ES005775 Yale J Biol Med (2013Dec 13)

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NEK8 links the ATR-regulated replication stressresponse and S phase CDK activity to renal ciliopath ...

Choi, Hyo Jei Claudia;Lin, Jia-Ren; Vannier,Jean-Baptiste; Slaats,Gisela G; Kile, AndrewC; ...

R01ES016486 Mol Cell (2013 Aug 22) 23973373

2013

NER initiation factors, DDB2 and XPC, regulate UVradiation response by recruiting ATR and ATM kinas...

Ray, Alo; Milum,Keisha; Battu, Aruna;Wani, Gulzar; Wani,Altaf A

R01ES012991 DNA Repair (Amst) (2013Apr 01)

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Novel methylation biomarker panel for the earlydetection of pancreatic cancer.

Yi, Joo Mi; Guzzetta,Angela A; Bailey,Vasudev J; Downing,Stephanie R; VanNeste, Leander; Ch ...

R01ES011858 Clin Cancer Res (2013Dec 01)

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Nucleosome dynamics regulates DNA processing. Adkins, Nicholas L;Niu, Hengyao; Sung,Patrick; Peterson, CraigL

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On the formation and properties of interstrandDNA-DNA cross-links forged by reaction of an abasics ...

Johnson, Kevin M;Price, Nathan E; Wang,Jin; Fekry, Mostafa I;Dutta, Sanjay; Seiner,Derrick ...

R01ES021007 J Am Chem Soc (2013 Jan23)

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p38 MAPK- and Akt-mediated p300 phosphorylationregulates its degradation to facilitate nucleotide e ...

Wang, Qi-En; Han,Chunhua; Zhao, Ran;Wani, Gulzar; Zhu,Qianzheng; Gong, Li;Battu, Aruna; R ...

R01ES012991 Nucleic Acids Res (2013Feb 01)

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p53 activation by Ni(II) is a HIF-1α independentresponse causing caspases 9/3-mediated apoptosis in ...

Wong, Victor C; Morse,Jessica L; Zhitkovich,Anatoly

P42ES013660,R01ES008786

Toxicol Appl Pharmacol(2013 Jun 15)

23566959

2013

PDIP38 is translocated to the spliceosomes/nuclearspeckles in response to UV-induced DNA damage and...

Wong, Agnes; Zhang,Sufang; Mordue, Dana;Wu, Joseph M; Zhang,Zhongtao;Darzynkiewicz, Zbigni...

R56ES014737 Cell Cycle (2013 Oct 01) 23989611

2013

PHD domain from human SHPRH. Machado, Luciana E F;Pustovalova, Yulia;Kile, Andrew C;Pozhidaeva, Alexandra;Cimprich, Karl ...

R01ES016486 J Biomol NMR (2013Aug)

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Pif1 helicase and Polýý promoterecombination-coupled DNA synthesis via bubblemigration.

Wilson, Marenda A;Kwon, YoungHo; Xu,Yuanyuan; Chung,Woo-Hyun; Chi, Peter;Niu, Hengyao; May ...

R01ES007061 Nature (2013 Oct 17) 24025768

2013

Postembryonic lineages of the Drosophila brain: I.Development of the lineage-associated fiber tract ...

Lovick, Jennifer K;Ngo, Kathy T; Omoto,Jaison J; Wong, DarrenC; Nguyen, Joseph D;Hartenstei ...

R01ES029357 Dev Biol (2013 Dec 15) 23880429

2013

RIF1 in DNA break repair pathway choice. Daley, James M; Sung,Patrick

R01ES007061 Mol Cell (2013 Mar 07) 23473603

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Role of direct reactivity with metals inchemoprotection by N-acetylcysteine againstchromium(VI), c ...


P42ES013660,R01ES008786

Free Radic Biol Med (2013Dec)

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2013

Role of replication protein A in double hollidayjunction dissolution mediated by the BLM-Topo IIIýý...

Xue, Xiaoyu; Raynard,Steven; Busygina,Valeria; Singh,Akhilesh K; Sung,Patrick


23543748

2013

Roles of DNA helicases in the mediation andregulation of homologous recombination.

Daley, James M; Niu,Hengyao; Sung, Patrick

R01ES007061 Adv Exp Med Biol (2013) 23161012

2013

Structure and function of the DNA ligases encoded bythe mammalian LIG3 gene.

Tomkinson, Alan E;Sallmyr, Annahita

R01ES012512 Gene (2013 Dec 01) 24013086

2013

Targeting abnormal DNA double-strand break repair intyrosine kinase inhibitor-resistant chronic mye ...

Tobin, L A; Robert, C;Rapoport, A P; Gojo, I;Baer, M R; Tomkinson,A E; Rassool, F V

R01ES012512 Oncogene (2013 Apr 04) 22641215

2013

Thymoquinone inhibits autophagy and inducescathepsin-mediated, caspase-independent cell death ingl ...

Racoma, Ira O; Meisen,Walter Hans; Wang,Qi-En; Kaur, Balveen;Wani, Altaf A

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2013

Uptake, p53 pathway activation, and cytotoxicresponses for Co(II) and Ni(II) in human lung cells: i...

Green, Samantha E;Luczak, Michal W;Morse, Jessica L;DeLoughery, Zachary;Zhitkovich, Anatoly

P42ES013660,R01ES008786

Toxicol Sci (2013 Dec) 24068677

2013

A DNA hypermethylation module for thestem/progenitor cell signature of cancer.

Easwaran, Hariharan;Johnstone, Sarah E;Van Neste, Leander;Ohm, Joyce;Mosbruger, Tim; Wang,...

R01ES011858 Genome Res (2012 May) 22391556

2012

A two-dimensional ERK-AKT signaling code for anNGF-triggered cell-fate decision.

Chen, Jia-Yun; Lin,Jia-Ren; Cimprich,Karlene A; Meyer,Tobias

R01ES016486 Mol Cell (2012 Jan 27) 22206868

2012

Characterization of human DNA polymerase delta andits subassemblies reconstituted by expression in ...

Zhou, Yajing; Meng,Xiao; Zhang, Sufang;Lee, Ernest Y C; Lee,Marietta Y W T

R56ES014737 PLoS One (2012) 22723953

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DNMT1 modulates gene expression without itscatalytic activity partially through its interactions wi ...

Clements, Eriko G;Mohammad, Helai P;Leadem, Benjamin R;Easwaran, Hariharan;Cai, Yi; Van Nes ...

R01ES011858 Nucleic Acids Res (2012May)

22278882

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Environmentally induced epigenetic transgenerationalinheritance of phenotype and disease.

Guerrero-Bosagna,Carlos; Skinner,Michael K

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Mol Cell Endocrinol (2012May 06)

22020198

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Epigenetic transgenerational inheritance of alteredstress responses.

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R01ES012974,R01ES012974

Proc Natl Acad Sci U S A(2012 Jun 5)

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Epigenetic transgenerational inheritance of somatictranscriptomes and epigenetic control regions.

Skinner, Michael K;Manikkam, Mohan;Haque, Md M; Zhang,Bin; Savenkova, MarinaI

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Genome Biol (2012 Oct03)

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Epigenetic transgenerational inheritance of vinclozolininduced mouse adult onset disease and associ ...

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R01ES012974,R01ES012974


23041264

2012

Extrachromosomal microDNAs and chromosomalmicrodeletions in normal tissues.

Shibata, Yoshiyuki;Kumar, Pankaj; Layer,Ryan; Willcox,Smaranda; Gagan,Jeffrey R; Griffith, ...

R56ES013773 Science (2012 Apr 06) 22403181

2012

Finally, polyubiquitinated PCNA gets recognized. Zeman, Michelle K;Cimprich, Karlene A

R01ES016486 Mol Cell (2012 Aug 10) 22883622

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Increased risk of lung cancer associated with afunctionally impaired polymorphic variant of the hum...

Dey, Sanjib; Maiti,Amit K; Hegde,Muralidhar L; Hegde,Pavana M; Boldogh,Istvan; Sarkar, Par ...

R01ES012512 DNA Repair (Amst) (2012Jun 01)

22497777

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Lack of CAK complex accumulation at DNA damagesites in XP-B and XP-B/CS fibroblasts reveals differe...

Zhu, Qianzheng; Wani,Gulzar; Sharma, Nidhi;Wani, Altaf

R01ES012991 DNA Repair (Amst) (2012Dec 1)

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2012

Mechanistic insights into RAD51-associated protein 1(RAD51AP1) action in homologous DNA repair.

Dunlop, Myun Hwa;Dray, Eloïse; Zhao,Weixing; San Filippo,Joseph; Tsai,Miaw-Sheue; Leung, S...


2012

Metabolism of Cr(VI) by ascorbate but not glutathioneis a low oxidant-generating process.

Wong, Victor;Armknecht, Susan;Zhitkovich, Anatoly

P42ES013660,R01ES008786

J Trace Elem Med Biol(2012 Jun)

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Novel attributes of Hed1 affect dynamics and activityof the Rad51 presynaptic filament during meiot ...

Busygina, Valeria;Saro, Dorina; Williams,Gareth; Leung,Wing-Kit; Say, AmandaF; Sehorn, Mic ...


2012

Nucleotide excision repair factor XPC enhances DNAdamage-induced apoptosis by downregulating the an ...

Wang, Qi-En; Han,Chunhua; Zhang, Bo;Sabapathy, Kanaga;Wani, Altaf A

R01ES012991 Cancer Res (2012 Feb 01) 22174370

2012

Perinatal exposure to 50 ppb sodium arsenate induceshypothalamic-pituitary-adrenal axis dysregulati ...

Goggin, Samantha L;Labrecque, Matthew T;Allan, Andrea M

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Pesticide and insect repellent mixture (permethrin andDEET) induces epigenetic transgenerational in ...

Manikkam, Mohan;Tracey, Rebecca;Guerrero-Bosagna,Carlos; Skinner,Michael K

R01ES012974,R01ES012974


22975477

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RAD51 protein ATP cap regulates nucleoproteinfilament stability.

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Role of DNA polymerases in repeat-mediated genomeinstability.

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R01ES015869 Cell Rep (2012 Nov 29) 23142667

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S-phase sensing of DNA-protein crosslinks triggersTopBP1-independent ATR activation and p53-mediate...

Wong, VictorChun-Lam; Cash,Haley L; Morse, JessicaL; Lu, Shan;Zhitkovich, Anatoly

R01ES008786 Cell Cycle (2012 Jul 01) 22722496

2012

Spatiotemporal recruitment of human DNApolymerase delta to sites of UV damage.

Chea, Jennifer; Zhang,Sufang; Zhao, Hong;Zhang, Zhongtao; Lee,Ernest Y C;Darzynkiewicz, Zb ...

R56ES014737 Cell Cycle (2012 Aug 01) 22801543

2012

Structure of monoubiquitinated PCNA: implicationsfor DNA polymerase switching and Okazaki fragment...

Zhang, Zhongtao;Zhang, Sufang; Lin, SzuHua Sharon; Wang,Xiaoxiao; Wu, Licheng;Lee, Ernest ...

R56ES014737 Cell Cycle (2012 Jun 01) 22592530

2012

Targeting abnormal DNA repair in therapy-resistantbreast cancers.

Tobin, Lisa A; Robert,Carine; Nagaria, Pratik;Chumsri, Saranya;Twaddell, William;Ioffe, Ol ...

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2012

The cancer epigenome: its origins, contributions totumorigenesis, and translational implications.

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The E288K colon tumor variant of DNA polymeraseýý is a sequence specific mutator.

Murphy, Drew L;Donigan, Katherine A;Jaeger, Joachim;Sweasy, Joann B


2012

The interaction between polynucleotide kinasephosphatase and the DNA repair protein XRCC1 iscritic ...

Della-Maria, Julie;Hegde, Muralidhar L;McNeill, Daniel R;Matsumoto, Yoshihiro;Tsai, Miaw-Sh ...


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The nucleotide sequence, DNA damage location, andprotein stoichiometry influence the base excision ...

Goula, Agathi-Vasiliki;Pearson, Christopher E;Della Maria, Julie;Trottier, Yvon;Tomkinson, ...

R01ES012512 Biochemistry (2012 May8)

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2012

Transgenerational actions of environmentalcompounds on reproductive disease and identificationof e ...

Manikkam, Mohan;Guerrero-Bosagna,Carlos; Tracey,Rebecca; Haque, MdM; Skinner, Michael K

R01ES012974,R01ES012974

PLoS One (2012) 22389676

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Undetectable role of oxidative DNA damage in cellcycle, cytotoxic and clastogenic effects of Cr(VI) ...

Reynolds, Mindy;Armknecht, Susan;Johnston, Tatiana;Zhitkovich, Anatoly

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Mutagenesis (2012 Jul) 22241526

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Y265C DNA polymerase beta knockin mice survivepast birth and accumulate base excision repair interm...

Senejani, Alireza G;Dalal, Shibani; Liu,Yanfeng; Nottoli,Timothy P; McGrath,James M; Clairm ...

R01ES019179 Proc Natl Acad Sci U S A(2012 Apr 24)

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Activation of protein kinase Tel1 through recognitionof protein-bound DNA ends.

Fukunaga, Kenzo;Kwon, Youngho; Sung,Patrick; Sugimoto,Katsunori

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2011

Analyses of the yeast Rad51 recombinase A265Vmutant reveal different in vivo roles of Swi2-like fac ...

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ASF1A and ATM regulate H3K56-mediated cell-cyclecheckpoint recovery in response to UV irradiation.

Battu, Aruna; Ray, Alo;Wani, Altaf A

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Cell cycle regulation of DNA double-strand break endresection by Cdk1-dependent Dna2 phosphorylatio ...

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Child health, developmental plasticity, and epigeneticprogramming.

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Endocr Rev (2011 Apr) 20971919

2011

Chromium in drinking water: sources, metabolism, andcancer risks.

Zhitkovich, Anatoly P42ES013660,R01ES008786

Chem Res Toxicol (2011Oct 17)

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Differential contributory roles of nucleotide excisionand homologous recombination repair for enhan ...

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Environmental epigenetic transgenerational inheritanceand somatic epigenetic mitotic stability.


Epigenetics (2011 Jul) 21637037

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Epigenetic transgenerational actions of endocrinedisruptors.

Skinner, Michael K;Manikkam, Mohan;Guerrero-Bosagna,Carlos

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Reprod Toxicol (2011 Apr) 21055462

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Genomic and epigenomic integration identifies aprognostic signature in colon cancer.

Yi, Joo Mi; Dhir,Mashaal; Van Neste,Leander; Downing,Stephanie R; Jeschke,Jana; Glöckner, ...

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Human Mre11/human Rad50/Nbs1 and DNA ligaseIIIalpha/XRCC1 protein complexes act together in analte ...

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2011

Hypoxia-induced epigenetic regulation and silencingof the BRCA1 promoter.

Lu, Yuhong; Chu,Adrian; Turker,Mitchell S; Glazer,Peter M

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Inhibition of hypoxia-induced miR-155 radiosensitizeshypoxic lung cancer cells.

Babar, Imran A;Czochor, Jennifer;Steinmetz, Allison;Weidhaas, Joanne B;Glazer, Peter M; Sla ...

R01ES005775 Cancer Biol Ther (2011Nov 15)

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Loss of a single Hic1 allele accelerates polypformation in Apc(Δ716) mice.

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R01ES011858 Oncogene (2011 Jun 9) 21297660

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Molecular basis for enhancement of the meiotic DMC1recombinase by RAD51 associated protein 1 (RAD51...

Dray, Eloïse; Dunlop,Myun Hwa; Kauppi,Liisa; San Filippo,Joseph; Wiese, Claudia;Tsai, Miaw ...

R01ES007061 Proc Natl Acad Sci U S A(2011 Mar 01)

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Nucleosome disruption by DNA ligase III-XRCC1promotes efficient base excision repair.

Odell, Ian D; Barbour,Joy-El; Murphy, DrewL; Della-Maria, Julie A;Sweasy, Joann B;Tomkinson ...

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Oxidative damage targets complexes containing DNAmethyltransferases, SIRT1, and polycomb members to...

O'Hagan, Heather M;Wang, Wei; Sen,Subhojit; DestefanoShields, Christina; Lee,Stella S; Zhan ...

R01ES011858,T32ES007141

Cancer Cell (2011 Nov 15) 22094255

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Participation of translesion synthesis DNApolymerases in the maintenance of chromosomeintegrity in ...

Kochenova, O V;Soshkina, J V;Stepchenkova, E I;Inge-Vechtomov, S G;Shcherbakova, P V

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Processing of DNA structures via DNA unwinding andbranch migration by the S. cerevisiae Mph1 protei ...

Zheng, Xiao-Feng;Prakash, Rohit; Saro,Dorina; Longerich,Simonne; Niu,Hengyao; Sung, Patric...

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RAD51-associated protein 1 (RAD51AP1) interactswith the meiotic recombinase DMC1 through aconserve ...

Dunlop, Myun Hwa;Dray, Eloïse; Zhao,Weixing; Tsai,Miaw-Sheue; Wiese,Claudia; Schild, David...

R01ES007061 J Biol Chem (2011 Oct 28) 21903585

2011

Reduced expression of MAPK/ERK genes in perinatalarsenic-exposed offspring induced by glucocorticoi ...

Martinez-Finley, EbanyJ; Goggin, Samantha L;Labrecque, Matthew T;Allan, Andrea M

R01ES019583 Neurotoxicol Teratol (2011Sep-Oct)

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Replication protein A safeguards genome integrity bycontrolling NER incision events.

Overmeer, René M;Moser, Jill; Volker,Marcel; Kool, Hanneke;Tomkinson, Alan E;van Zeeland, ...

R01ES012512 J Cell Biol (2011 Feb 07) 21282463

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Role of epigenetics in developmental biology andtransgenerational inheritance.


Birth Defects Res CEmbryo Today (2011 Mar)

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SHPRH and HLTF act in a damage-specific manner tocoordinate different forms of postreplication repa ...

Lin, Jia-Ren; Zeman,Michelle K; Chen,Jia-Yun; Yee,Muh-Ching; Cimprich,Karlene A

R01ES016486 Mol Cell (2011 Apr 22) 21396873

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Stem cell protein Piwil2 modulates chromatinmodifications upon cisplatin treatment.

Wang, Qi-En; Han,Chunhua; Milum,Keisha; Wani, Altaf A

R01ES012991 Mutat Res (2011 Mar 15) 21310163

2011

The non-canonical protein binding site at themonomer-monomer interface of yeast proliferating cell...

Sharma, Neeru M;Kochenova, Olga V;Shcherbakova, Polina V


2011

The Rad50 coiled-coil domain is indispensable forMre11 complex functions.

Hohl, Marcel; Kwon,Youngho; Galván,Sandra Muñoz; Xue,Xiaoyu; Tous, Cristina;Aguilera, Andr ...

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Thymoquinone up-regulates PTEN expression andinduces apoptosis in doxorubicin-resistant humanbreas ...

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A cancer-associated DNA polymerase delta variantmodeled in yeast causes a catastrophic increase in ...

Daee, Danielle L;Mertz, Tony M;Shcherbakova, Polina V

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Aberrant silencing of cancer-related genes by CpGhypermethylation occurs independently of their spa ...

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R01ES011858 Cancer Res (2010 Oct 15) 20736368

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Alterations in the developing testis transcriptomefollowing embryonic vinclozolin exposure.

Clement, Tracy M;Savenkova, Marina I;Settles, Matthew;Anway, Matthew D;Skinner, Michael K

R01ES012974,R01ES012974

Reprod Toxicol (2010Nov)

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Basic helix-loop-helix transcription factor gene familyphylogenetics and nomenclature.

Skinner, Michael K;Rawls, Alan;Wilson-Rawls, Jeanne;Roalson, Eric H

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Differentiation (2010 Jul) 20219281

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Checkpoint recovery after DNA damage: a rolling stopfor CDKs.

Duursma, Anja M;Cimprich, Karlene A

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Continued primer synthesis at stalled replication forkscontributes to checkpoint activation.

Van, Christopher; Yan,Shan; Michael, WMatthew; Waga, Shou;Cimprich, Karlene A

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Crystal structures of RMI1 and RMI2, two OB-foldregulatory subunits of the BLM complex.

Wang, Feng; Yang,Yuting; Singh, ThiyamRamsing; Busygina,Valeria; Guo, Rong;Wan, Ke; Wang, ...

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Dissociation of CAK from core TFIIH reveals afunctional link between XP-G/CS and the TFIIHdisassem ...

Arab, Hany H; Wani,Gulzar; Ray, Alo; Shah,Zubair I; Zhu,Qianzheng; Wani, AltafA

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DNA polymerases at the eukaryotic fork-20 years later.

Pavlov, Youri I;Shcherbakova, Polina V

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Enhancement of RAD51 recombinase activity by thetumor suppressor PALB2.

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Epigenetic transgenerational actions of environmentalfactors in disease etiology.

Skinner, Michael K;Manikkam, Mohan;Guerrero-Bosagna,Carlos

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Trends Endocrinol Metab(2010 Apr)

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Epigenetic transgenerational actions of vinclozolin onpromoter regions of the sperm epigenome.

Guerrero-Bosagna,Carlos; Settles,Matthew; Lucker, Ben;Skinner, Michael K

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PLoS One (2010) 20927350

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Functional capacity of XRCC1 protein variantsidentified in DNA repair-deficient Chinese hamsterova ...

Berquist, Brian R;Singh, DharmendraKumar; Fan, Jinshui;Kim, Daemyung;Gillenwater, Elizabeth...


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Histone modifications: crucial elements for damageresponse and chromatin restoration.

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Hsp27 protects adenocarcinoma cells fromUV-induced apoptosis by Akt and p21-dependentpathways of s ...

Kanagasabai, Ragu;Karthikeyan,Krishnamurthy; Vedam,Kaushik; Qien, Wang;Zhu, Qianzheng; Ilan ...

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Human DNA ligase III recognizes DNA ends bydynamic switching between two DNA-bound states.

Cotner-Gohara,Elizabeth; Kim,In-Kwon; Hammel,Michal; Tainer, John A;Tomkinson, Alan E;Elle ...


2010

Inhibition of poly(ADP-ribose) polymerasedown-regulates BRCA1 and RAD51 in a pathwaymediated by E2 ...

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Mapping networks of protein-mediated physicalinteractions between chromatin elements.

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Mechanism of DNA-protein cross-linking bychromium.

Macfie, Andrea; Hagan,Elizabeth; Zhitkovich,Anatoly

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Chem Res Toxicol (2010Feb 15)

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Mechanism of the ATP-dependent DNA end-resectionmachinery from Saccharomyces cerevisiae.

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Metabolic disorders: Fathers' nutritional legacy. Skinner, Michael K R01ES012974,R01ES012974

Nature (2010 Oct 21) 20962833

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MHF1-MHF2, a histone-fold-containing proteincomplex, participates in the Fanconi anemia pathwayvia ...

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Overexpression of DDB2 enhances the sensitivity ofhuman ovarian cancer cells to cisplatin by augmen ...

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Participation of DNA polymerase zeta in replication ofundamaged DNA in Saccharomyces cerevisiae.

Northam, Matthew R;Robinson, Heather A;Kochenova, Olga V;Shcherbakova, Polina V

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Potentiation of temozolomide cytotoxicity byinhibition of DNA polymerase beta is accentuated byBRC ...

Stachelek, Gregory C;Dalal, Shibani;Donigan, Katherine A;Campisi Hegan, Denise;Sweasy, Joan ...

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Promotion and regulation of homologousrecombination by DNA helicases.

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Rad52 SUMOylation affects the efficiency of the DNArepair.

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Role of nuclear architecture in epigenetic alterations incancer.

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Stress and the epigenetic landscape: a link to thepathobiology of human diseases?

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Targeting abnormal DNA double strand break repair incancer.

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XPA impacts formation but not proteasome-sensitiverepair of DNA-protein cross-links induced by chro ...

Zecevic, Alma; Hagan,Elizabeth; Reynolds,Mindy; Poage, Graham;Johnston, Tatiana;Zhitkovich, ...

P42ES013660,R01ES008786

Mutagenesis (2010 Jul) 20410141

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XRCC1 deficiency sensitizes human lung epithelialcells to genotoxicity by crocidolite asbestos and ...

Pietruska, Jodie R;Johnston, Tatiana;Zhitkovich, Anatoly;Kane, Agnes B

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Environ Health Perspect(2010 Dec)

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A deficiency of lunatic fringe is associated with cysticdilation of the rete testis.

Hahn, K L; Beres, B;Rowton, Megan J;Skinner, M K; Chang,Y; Rawls, A;Wilson-Rawls, J

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Reproduction (2009 Jan) 18801836

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A genome-wide siRNA screen reveals diverse cellularprocesses and pathways that mediate genome stabi ...

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R01ES016486 Mol Cell (2009 Jul 31) 19647519

2009

Assay for human Rad51-mediated DNA displacementloop formation.

Raynard, Steven; Sung,Patrick

R01ES007061 Cold Spring Harb Protoc(2009 Jan)

20147015

2009

Chromatin restoration following nucleotide excisionrepair involves the incorporation of ubiquitinat ...

Zhu, Qianzheng; Wani,Gulzar; Arab, Hany H;El-Mahdy, MohamedA; Ray, Alo; Wani,Altaf A

R01ES012991 DNA Repair (Amst) (2009Feb 01)

19059499

2009

Cooperativity of Mus81.Mms4 with Rad54 in theresolution of recombination and replication intermedia...

Matulova, Petra;Marini, Victoria;Burgess, Rebecca C;Sisakova, Alexandra;Kwon, Youngho; Roth...


19129197

2009

Distinct kinetics of human DNA ligases I, IIIalpha,IIIbeta, and IV reveal direct DNA sensing abilit ...

Chen, Xi; Ballin, Jeff D;Della-Maria, Julie; Tsai,Miaw-Sheue; White,Elizabeth J; Tomkinson,...

R01ES012512 DNA Repair (Amst) (2009Aug 6)

19589734

2009

DNA damage alters DNA polymerase delta to a formthat exhibits increased discrimination against modi ...

Meng, Xiao; Zhou,Yajing; Zhang, Sufang;Lee, Ernest Y C; Frick,David N; Lee, MariettaY W T

R56ES014737 Nucleic Acids Res (2009Feb)

19074196

2009

DNA damage tolerance: when it's OK to makemistakes.

Chang, Debbie J;Cimprich, Karlene A

R01ES016486 Nat Chem Biol (2009 Feb) 19148176

2009

Emerging roles of microRNAs in the molecularresponses to hypoxia.

Crosby, Meredith E;Devlin, Cecilia M;Glazer, Peter M; Calin,George A; Ivan, Mircea

R01ES005775 Curr Pharm Des (2009) 19925433

2009

Environmental signals and transgenerationalepigenetics.

Skinner, Michael K;Guerrero-Bosagna,Carlos

R01ES012974,R01ES012974

Epigenomics (2009 Oct) 20563319

2009

Epigenetic transgenerational effects of endocrinedisruptors on male reproduction.

Guerrero-Bosagna,Carlos M; Skinner,Michael K

R01ES012974,R01ES012974

Semin Reprod Med (2009Sep)

19711250

2009

Functional interactions of meiotic recombinationfactors Rdh54 and Dmc1.

Chi, Peter; Kwon,Youngho; Moses, DanaN; Seong, Changhyun;Sehorn, Michael G;Singh, Akhilesh ...

R01ES007061 DNA Repair (Amst) (2009Feb 1)

19028606

2009

Functional significance of the Rad51-Srs2 complex inRad51 presynaptic filament disruption.

Colavito, Sierra;Macris-Kiss, Margaret;Seong, Changhyun;Gleeson, Olive; Greene,Eric C; Klei ...

R01ES007061 Nucleic Acids Res (2009Nov)

19745052

2009

HARPing on about the DNA damage response duringreplication.

Driscoll, Robert;Cimprich, Karlene A

R01ES016486 Genes Dev (2009 Oct 15) 19833762

2009

Human SNF5/INI1, a component of the humanSWI/SNF chromatin remodeling complex, promotesnucleotide ...

Ray, Alo; Mir, Safita N;Wani, Gulzar; Zhao,Qun; Battu, Aruna; Zhu,Qianzheng; Wang,Qi-En; ...

R01ES012991 Mol Cell Biol (2009 Dec) 19805520

2009

Localization of recombination proteins and Srs2reveals anti-recombinase function in vivo.

Burgess, Rebecca C;Lisby, Michael;Altmannova, Veronika;Krejci, Lumir; Sung,Patrick; Rothste ...

R01ES007061 J Cell Biol (2009 Jun 15) 19506039

2009

MicroRNA regulation of DNA repair gene expressionin hypoxic stress.

Crosby, Meredith E;Kulshreshtha, Ritu;Ivan, Mircea; Glazer,Peter M


2009

Modulation of nucleotide excision repair bymammalian SWI/SNF chromatin-remodeling complex.

Zhao, Qun; Wang,Qi-En; Ray, Alo; Wani,Gulzar; Han, Chunhua;Milum, Keisha; Wani,Altaf A


2009

Progesterone regulation of primordial follicleassembly in bovine fetal ovaries.


R01ES012974,R01ES012974

Mol Cell Endocrinol (2009Dec 10)

19747959

2009

Proliferating cell nuclear antigen uses two distinctmodes to move along DNA.

Kochaniak, Anna B;Habuchi, Satoshi;Loparo, Joseph J;Chang, Debbie J;Cimprich, Karlene A;Wa ...

R01ES016486 J Biol Chem (2009 Jun 26) 19411704

2009

Rapid DNA double-strand breaks resulting fromprocessing of Cr-DNA cross-links by both MutSdimers.

Reynolds, Mindy F;Peterson-Roth,Elizabeth C; Bespalov,Ivan A; Johnston,Tatiana; Gurel, Volk ...


2009

Regulation of Rad51 recombinase presynapticfilament assembly via interactions with the Rad52mediat ...

Seong, Changhyun;Colavito, Sierra; Kwon,Youngho; Sung,Patrick; Krejci, Lumir


2009

Role of the Rad52 amino-terminal DNA bindingactivity in DNA strand capture in homologousrecombinat ...

Shi, Idina; Hallwyl,Swee C L; Seong,Changhyun; Mortensen,Uffe; Rothstein,Rodney; Sung, Pat ...


19812039

2009

Sem1p and Ubp6p orchestrate telomeric silencing bymodulating histone H2B ubiquitination and H3 acet ...

Qin, Song; Wang, Qien;Ray, Alo; Wani, Gulzar;Zhao, Qun; Bhaumik,Sukesh R; Wani, AltafA

R01ES012991 Nucleic Acids Res (2009Apr)

19188254

2009

Structural transitions within human Rad51nucleoprotein filaments.

Robertson, Ragan B;Moses, Dana N; Kwon,YoungHo; Chan,Pamela; Chi, Peter;Klein, Hannah; Sun ...

R01ES007061 Proc Natl Acad Sci U S A(2009 Aug 4)

19622740

2009

Tangeretin sensitizes cisplatin-resistant human ovariancancer cells through downregulation of phosp ...

Arafa, El-Shaimaa A;Zhu, Qianzheng;Barakat, Bassant M;Wani, Gulzar; Zhao,Qun; El-Mahdy, Mo ...

R01ES012991 Cancer Res (2009 Dec 01) 19903849

2009

Visualizing the disassembly of S. cerevisiae Rad51nucleoprotein filaments.

Robertson, Ragan B;Moses, Dana N; Kwon,YoungHo; Chan,Pamela; Zhao, Weixing;Chi, Peter; Kle ...

R01ES007061 J Mol Biol (2009 May 15) 19327367

2009

WRN helicase promotes repair of DNA double-strandbreaks caused by aberrant mismatch repair of chrom ...

Zecevic, Alma; Menard,Haley; Gurel, Volkan;Hagan, Elizabeth;DeCaro, Rosamaria;Zhitkovich, ...

P42ES013660,R01ES008786,T32ES007272

Cell Cycle (2009 Sep 01) 19652551

2009

Yeast Mph1 helicase dissociates Rad51-made D-loops:implications for crossover control in mitotic re ...

Prakash, Rohit; Satory,Dominik; Dray, Eloïse;Papusha, Almas;Scheller, Jürgen;Kramer, Wilfr ...

R01ES007061 Genes Dev (2009 Jan 01) 19136626

2009

A novel 6C assay uncovers Polycomb-mediated higherorder chromatin conformations.

Tiwari, Vijay K; Cope,Leslie; McGarvey,Kelly M; Ohm, JoyceE; Baylin, Stephen B

R01ES011858 Genome Res (2008 Jul) 18502945

2008

A requirement for DICER to maintain full promoterCpG island hypermethylation in human cancer cells.

Ting, Angela H; Suzuki,Hiromu; Cope, Leslie;Schuebel, Kornel E;Lee, Byron H; Toyota,Minoru ...


2008

Abnormal DNA methylation of CD133 in colorectaland glioblastoma tumors.

Yi, Joo Mi; Tsai,Hsing-Chen; Glöckner,Sabine C; Lin, Steven;Ohm, Joyce E;Easwaran, Hari; J ...

R01ES011858 Cancer Res (2008 Oct 01) 18829568

2008

ATP-dependent chromatin remodeling by theSaccharomyces cerevisiae homologous recombinationfactor R ...

Kwon, YoungHo;Seong, Changhyun;Chi, Peter; Greene, EricC; Klein, Hannah;Sung, Patrick


2008

ATR: an essential regulator of genome integrity. Cimprich, Karlene A;Cortez, David

R01ES016486 Nat Rev Mol Cell Biol(2008 Aug)

18594563

2008

Chronic hypoxia decreases synthesis of homologousrecombination proteins to offset chemoresistance a ...

Chan, Norman;Koritzinsky, Marianne;Zhao, Helen; Bindra,Ranjit; Glazer, Peter M;Powell, Sim ...


2008

Convergence of mutation and epigenetic alterationsidentifies common genes in cancer that predict fo ...

Chan, Timothy A;Glockner, Sabine; Yi,Joo Mi; Chen, Wei; VanNeste, Leander; Cope,Leslie; He ...

R01ES011858 PLoS Med (2008 May 27) 18507500

2008

Defining a chromatin pattern that characterizesDNA-hypermethylated genes in colon cancer cells.

McGarvey, Kelly M;Van Neste, Leander;Cope, Leslie; Ohm,Joyce E; Herman, JamesG; Van Criekin ...

R01ES011858 Cancer Res (2008 Jul 15) 18632628

2008

Epigenetic inactivation of the canonical Wntantagonist SRY-box containing gene 17 in colorectalcan ...

Zhang, Wei; Glöckner,Sabine C; Guo,Mingzhou; Machida,Emi Ota; Wang, DavidH; Easwaran, Hari ...


2008

Epigenetic programming of the germ line: effects ofendocrine disruptors on the development of trans ...

Anway, Matthew D;Skinner, Michael K

R01ES012974,R01ES012974

Reprod Biomed Online(2008 Jan)

18252044

2008

Eukaryotic DNA ligases: structural and functionalinsights.

Ellenberger, Tom;Tomkinson, Alan E

R01ES012512 Annu Rev Biochem (2008) 18518823

2008

Genetic and epigenetic mechanisms in metalcarcinogenesis and cocarcinogenesis: nickel, arsenic,and ...

Salnikow, Konstantin;Zhitkovich, Anatoly

P42ES013660,R01ES008786

Chem Res Toxicol (2008Jan)

17970581

2008

Identification and validation of human DNA ligaseinhibitors using computer-aided drug design.

Zhong, Shijun; Chen,Xi; Zhu, Xiao;Dziegielewska, Barbara;Bachman, Kurtis E;Ellenberger, To ...

R01ES012512 J Med Chem (2008 Aug14)

18630893

2008

Integration of CREB and bHLH transcriptionalsignaling pathways through direct heterodimerizationof ...

Muir, Tera;Wilson-Rawls, Jeanne;Stevens, Jeffrey D;Rawls, Alan;Schweitzer, Ronen;Kang, Ch ...

R01ES012974,R01ES012974

Mol Reprod Dev (2008Nov)

18361414

2008

Interaction with RPA is necessary for Rad52 repaircenter formation and for its mediator activity.

Plate, Iben; Hallwyl,Swee C L; Shi, Idina;Krejci, Lumir; Muller,Christian; Albertsen,Line; ...


2008

Molecular anatomy of the recombination mediatorfunction of Saccharomyces cerevisiae Rad52.

Seong, Changhyun;Sehorn, Michael G;Plate, Iben; Shi, Idina;Song, Binwei; Chi,Peter; Morten ...

R01ES007061 J Biol Chem (2008 May 2) 18310075

2008

Naringenin protects HaCaT human keratinocytesagainst UVB-induced apoptosis and enhances theremoval ...

El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-En; Wani,Gulzar; Patnaik,Srinivas; Zhao, Qun; ...

R01ES012991 Photochem Photobiol(2008 Mar-Apr)

18086244

2008

PcG proteins, DNA methylation, and gene repressionby chromatin looping.

Tiwari, Vijay K;McGarvey, Kelly M;Licchesi, Julien D F;Ohm, Joyce E; Herman,James G; Schübe ...

R01ES011858 PLoS Biol (2008 Dec 02) 19053175

2008

PCNA is ubiquitinated by RNF8. Zhang, Sufang; Chea,Jennifer; Meng, Xiao;Zhou, Yajing; Lee,Ernest Y C; Lee,Marietta Y W T

R56ES014737 Cell Cycle (2008 Nov 01) 18948756

2008

Phylogenetic and expression analysis of the basichelix-loop-helix transcription factor gene family: ...

Stevens, Jeffrey D;Roalson, Eric H;Skinner, Michael K

R01ES012974,R01ES012974

Differentiation (2008 Nov) 18557763

2008

Rad52 multimerization is important for its nuclearlocalization in Saccharomyces cerevisiae.

Plate, Iben; Albertsen,Line; Lisby, Michael;Hallwyl, Swee C L;Feng, Qi; Seong,Changhyun; R ...

R01ES007061 DNA Repair (Amst) (2008Jan 1)

17888746

2008

Rational design of human DNA ligase inhibitors thattarget cellular DNA replication and repair.

Chen, Xi; Zhong,Shijun; Zhu, Xiao;Dziegielewska, Barbara;Ellenberger, Tom;Wilson, Gerald M ...

R01ES012512 Cancer Res (2008 May 1) 18451142

2008

Reduction with glutathione is a weakly mutagenicpathway in chromium(VI) metabolism.

Guttmann, David;Poage, Graham;Johnston, Tatiana;Zhitkovich, Anatoly

P42ES013660,R01ES008786

Chem Res Toxicol (2008Nov)

18808157

2008

Remodeling of the human papillomavirus type 11replication origin into discrete nucleoprotein partic ...

Sim, Jeonggu; Ozgur,Sezgin; Lin, BiingYuan; Yu, Jei-Hwa;Broker, Thomas R;Chow, Louise T; G ...

R56ES013773 J Mol Biol (2008 Jan 25) 18067922

2008

The chromate-inducible chrBACF operon from thetransposable element TnOtChr confers resistance to ch...

Branco, Rita; Chung,Ana Paula; Johnston,Tatiana; Gurel, Volkan;Morais, Paula;Zhitkovich, A ...

P42ES013660,R01ES008786

J Bacteriol (2008 Nov) 18776016

2008

The p38 mitogen-activated protein kinase augmentsnucleotide excision repair by mediating DDB2 degra ...

Zhao, Qun; Barakat,Bassant M; Qin, Song;Ray, Alo; El-Mahdy,Mohamed A; Wani,Gulzar; Arafa, ...


18806262

2008

Transforming growth factor beta (TGFbeta1,TGFbeta2 and TGFbeta3) null-mutant phenotypes inembryoni ...

Memon, Mushtaq A;Anway, Matthew D;Covert, Trevor R;Uzumcu, Mehmet;Skinner, Michael K

R01ES012974,R01ES012974

Mol Cell Endocrinol (2008Nov 6)

18790002

2008

Transgenerational epigenetic programming of theembryonic testis transcriptome.

Anway, Matthew D;Rekow, Stephen S;Skinner, Michael K

R01ES012974,R01ES012974

Genomics (2008 Jan) 18042343

2008

Two DNA-binding and nick recognition modules inhuman DNA ligase III.

Cotner-Gohara,Elizabeth; Kim,In-Kwon; Tomkinson,Alan E; Ellenberger,Tom


2008

Up-regulation of WRN and DNA ligase IIIalpha inchronic myeloid leukemia: consequences for the repai...

Sallmyr, Annahita;Tomkinson, Alan E;Rassool, Feyruz V

R01ES012512 Blood (2008 Aug 15) 18524993

2008

What is an epigenetic transgenerational phenotype? F3or F2.


Reprod Toxicol (2008 Jan) 17949945

2008

Analyzing the ATR-mediated checkpoint usingXenopus egg extracts.

Lupardus, Patrick J;Van, Christopher;Cimprich, Karlene A

R01ES016486 Methods (2007 Feb) 17189864

2007

Ascorbate acts as a highly potent inducer of chromatemutagenesis and clastogenesis: linkage to DNA ...

Reynolds, Mindy;Stoddard, Lauren;Bespalov, Ivan;Zhitkovich, Anatoly

R01ES008786,T32ES007272

Nucleic Acids Res (2007) 17169990

2007

Bipartite stimulatory action of the Hop2-Mnd1complex on the Rad51 recombinase.

Chi, Peter; San Filippo,Joseph; Sehorn,Michael G; Petukhova,Galina V; Sung, Patrick

R01ES007061 Genes Dev (2007 Jul 15) 17639080

2007

Cellular vitamin C increases chromate toxicity via adeath program requiring mismatch repair but not ...

Reynolds, Mindy;Zhitkovich, Anatoly

R01ES008786 Carcinogenesis (2007 Jul) 17301063

2007

Co-repression of mismatch repair gene expression byhypoxia in cancer cells: role of the Myc/Max net ...

Bindra, Ranjit S;Glazer, Peter M

R01ES005775 Cancer Lett (2007 Jul 8) 17275176

2007

Comparing the DNA hypermethylome with genemutations in human colorectal cancer.

Schuebel, Kornel E;Chen, Wei; Cope,Leslie; Glöckner,Sabine C; Suzuki,Hiromu; Yi, Joo-Mi; C...

R01ES011858 PLoS Genet (2007 Sep) 17892325

2007

DNA methylation and complete transcriptionalsilencing of cancer genes persist after depletion of EZ...

McGarvey, Kelly M;Greene, Eriko; Fahrner,Jill A; Jenuwein,Thomas; Baylin,Stephen B

R01ES011858 Cancer Res (2007 Jun 1) 17545586

2007

Epigenetic transgenerational actions of vinclozolin onthe development of disease and cancer.

Skinner, Michael K;Anway, Matthew D

R01ES012974,R01ES012974

Crit Rev Oncog (2007Aug)

17956218

2007

hTERT is expressed in cancer cell lines despitepromoter DNA methylation by preservation ofunmethyl ...

Zinn, Rebekah L; Pruitt,Kevin; Eguchi, Sayaka;Baylin, Stephen B;Herman, James G


2007

Inhibition of lysine-specific demethylase 1 bypolyamine analogues results in reexpression of aberra...

Huang, Yi; Greene,Eriko; Murray Stewart,Tracy; Goodwin,Andrew C; Baylin,Stephen B; Woster, ...

R01ES011858 Proc Natl Acad Sci U S A(2007 May 8)

17463086

2007

Lessons from 50 years of SOS DNA-damage-inducedmutagenesis.

Schlacher, Katharina;Goodman, Myron F


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2007

Probing ATR activation with model DNA templates. Cimprich, Karlene A R01ES016486 Cell Cycle (2007 Oct 01) 17700074

2007 Repression of RAD51 gene expression by E2F4/p130complexes in hypoxia.

Bindra, R S; Glazer, PM

R01ES005775 Oncogene (2007 Mar 29) 17001309

2007

Role of Claspin in regulation of nucleotide excisionrepair factor DDB2.

Praetorius-Ibba, Mette;Wang, Qi-En; Wani,Gulzar; El-Mahdy,Mohamed A; Zhu,Qianzheng; Qin, S ...

R01ES012991 DNA Repair (Amst) (2007May 01)

17196446

2007

Role of Dnl4-Lif1 in nonhomologous end-joiningrepair complex assembly and suppression ofhomologous ...

Zhang, Yu; Hefferin,Melissa L; Chen, Ling;Shim, Eun Yong;Tseng, Hui-Min; Kwon,Youngho; Sun ...

R01ES007061 Nat Struct Mol Biol (2007Jul)

17589524

2007

The ATR pathway: fine-tuning the fork. Paulsen, Renee D;Cimprich, Karlene A

R01ES016486 DNA Repair (Amst) (2007Jul 01)

17531546

2007

The epigenomics of cancer. Jones, Peter A; Baylin,Stephen B

R01ES011858 Cell (2007 Feb 23) 17320506

2007

The structural determinants of checkpoint activation. MacDougall, ChristinaA; Byun, Tony S; Van,Christopher; Yee,Muh-ching; Cimprich,Karlene A

R01ES016486 Genes Dev (2007 Apr 15) 17437996

2007

The ubiquitin-proteasome system regulatesp53-mediated transcription at p21waf1 promoter.

Zhu, Q; Wani, G; Yao,J; Patnaik, S; Wang,Q-E; El-Mahdy, M A;Praetorius-Ibba, M;Wani, A A

R01ES012991 Oncogene (2007 Jun 21) 17224908

2007

Transgenerational epigenetic imprints on matepreference.

Crews, David; Gore,Andrea C; Hsu,Timothy S; Dangleben,Nygerma L; Spinetta,Michael; Schaller ...

R01ES012974,R01ES012974

Proc Natl Acad Sci U S A(2007 Apr 3)

17389367

2007

Ubiquitylation-independent degradation of Xerodermapigmentosum group C protein is required for effi ...

Wang, Qi-En;Praetorius-Ibba, Mette;Zhu, Qianzheng;El-Mahdy, MohamedA; Wani, Gulzar; Zhao,...


2007

Ascorbate depletion mediates up-regulation ofhypoxia-associated proteins by cell density and nickel...

Karaczyn, Aldona;Ivanov, Sergey;Reynolds, Mindy;Zhitkovich, Anatoly;Kasprzak, Kazimierz S;...

R01ES008786 J Cell Biochem (2006 Apr1)

16288478

2006

ATM mediates oxidative stress-induceddephosphorylation of DNA ligase IIIalpha.

Dong, Zhiwan;Tomkinson, Alan E


2006

Basal repression of BRCA1 by multiple E2Fs andpocket proteins at adjacent E2F sites.

Bindra, Ranjit S;Glazer, Peter M

R01ES005775 Cancer Biol Ther (2006Oct)

17106239

2006

Causes of DNA single-strand breaks during reductionof chromate by glutathione in vitro and in cells ...

Messer, Joseph;Reynolds, Mindy;Stoddard, Lauren;Zhitkovich, Anatoly

R01ES008786,T32ES007272

Free Radic Biol Med (2006Jun 1)

16716899

2006

CHK2-dependent phosphorylation of BRCA1 inhypoxia.

Gibson, Shannon L;Bindra, Ranjit S;Glazer, Peter M

R01ES005775 Radiat Res (2006 Oct) 17007555

2006

Cullin 4A-mediated proteolysis of DDB2 protein atDNA damage sites regulates in vivo lesion recognit ...

El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-en; Wani,Gulzar; Praetorius-Ibba,Mette; Wani, ...


16527807

2006

De novo CpG island methylation in human cancercells.

Jair, Kam-Wing;Bachman, Kurtis E;Suzuki, Hiromu; Ting,Angela H; Rhee, Ina;Yen, Ray-Whay Ch ...


2006

Differential requirement for DNA methyltransferase 1in maintaining human cancer cell gene promoter ...

Ting, Angela H; Jair,Kam-wing; Schuebel,Kornel E; Baylin,Stephen B


2006

Differing patterns of genetic instability in micedeficient in the mismatch repair genes Pms2, Mlh1, ...

Hegan, Denise Campisi;Narayanan, Latha; Jirik,Frank R; Edelmann,Winfried; Liskay, RMichael; ...

R01ES005775 Carcinogenesis (2006 Dec) 16728433

2006

DNA damage binding protein component DDB1participates in nucleotide excision repair throughDDB2 DN ...

Li, Jinyou; Wang,Qi-En; Zhu, Qianzheng;El-Mahdy, MohamedA; Wani, Gulzar;Praetorius-Ibba, M ...

R01ES012991 Cancer Res (2006 Sep 01) 16951172

2006

DNA ligases: structure, reaction mechanism, andfunction.

Tomkinson, Alan E;Vijayakumar,Sangeetha; Pascal, JohnM; Ellenberger, Tom

R01ES012512 Chem Rev (2006 Feb) 16464020

2006

Human DNA ligases I, III, and IV-purification andnew specific assays for these enzymes.

Chen, Xi; Pascal, John;Vijayakumar,Sangeetha; Wilson,Gerald M; Ellenberger,Tom; Tomkinson, ...

R01ES012512 Methods Enzymol (2006) 16793394

2006

Lower mutagenicity but higher stability of Cr-DNAadducts formed during gradual chromate activation ...

Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly

P42ES013660,R01ES008786

Carcinogenesis (2006 Nov) 16714765

2006

Monoubiquitination of proliferating cell nuclearantigen induced by stalled replication requires unc ...

Chang, Debbie J;Lupardus, Patrick J;Cimprich, Karlene A


2006

NEIL2-initiated, APE-independent repair of oxidizedbases in DNA: Evidence for a repair complex in h ...

Das, Aditi; Wiederhold,Lee; Leppard, John B;Kedar, Padmini; Prasad,Rajendra; Wang,Huxian; ...

R01ES012512 DNA Repair (Amst) (2006Dec 09)

16982218

2006

Overexpression of the DNA mismatch repair factor,PMS2, confers hypermutability and DNA damagetoler ...

Gibson, Shannon L;Narayanan, Latha;Hegan, Denise Campisi;Buermeyer, Andrew B;Liskay, R Mich ...

R01ES005775 Cancer Lett (2006 Dec 8) 16426742

2006

RecA acts in trans to allow replication of damagedDNA by DNA polymerase V.

Schlacher, Katharina;Cox, Michael M;Woodgate, Roger;Goodman, Myron F

R01ES029680 Nature (2006 Aug 24) 16929290

2006

Recombination mediator and Rad51 targeting activitiesof a human BRCA2 polypeptide.

San Filippo, Joseph;Chi, Peter; Sehorn,Michael G; Etchin,Julia; Krejci, Lumir;Sung, Patric ...


2006

Roles of ATP binding and ATP hydrolysis in humanRad51 recombinase function.

Chi, Peter; Van Komen,Stephen; Sehorn,Michael G; Sigurdsson,Stefan; Sung, Patrick

R01ES007061 DNA Repair (Amst) (2006Mar 7)

16388992

2006

Silenced tumor suppressor genes reactivated by DNAdemethylation do not return to a fully euchromati ...

McGarvey, Kelly M;Fahrner, Jill A; Greene,Eriko; Martens, Joost;Jenuwein, Thomas;Baylin, S ...


2006

Yeast recombination factor Rdh54 functionallyinteracts with the Rad51 recombinase and catalyzesRad ...

Chi, Peter; Kwon,Youngho; Seong,Changhyun; Epshtein,Anastasiya; Lam,Isabel; Sung, Patrick; ...


2006

Aberrant gene silencing in tumor progression:implications for control of cancer.

Baylin, S B; Chen, W Y R01ES011858 Cold Spring Harb SympQuant Biol (2005)

16869780

2005

Cellular ubiquitination and proteasomal functionspositively modulate mammalian nucleotide excision ...

Wang, Qi-En; Wani,Manzoor A; Chen,Jianming; Zhu,Qianzheng; Wani,Gulzar; El-Mahdy,Mohamed ...

R01ES012991 Mol Carcinog (2005 Jan) 15547920

2005

Deubiquitination by proteasome is coordinated withsubstrate translocation for proteolysis in vivo.

Zhu, Qianzheng; Wani,Gulzar; Wang, Qi-en;El-mahdy, Mohamed;Snapka, Robert M;Wani, Altaf A

R01ES012991 Exp Cell Res (2005 Jul 15) 15950624

2005

DNA repair factor XPC is modified by SUMO-1 andubiquitin following UV irradiation.

Wang, Qi-En; Zhu,Qianzheng; Wani,Gulzar; El-Mahdy,Mohamed A; Li,Jinyou; Wani, Altaf A


2005

Effect of amino acid substitutions in the rad50 ATPbinding domain on DNA double strand break repair ...

Chen, Ling; Trujillo,Kelly M; Van Komen,Stephen; Roh, DongHyun; Krejci, Lumir;Lewis, L Kev ...


2005

Hypoxia down-regulates DNA double strand breakrepair gene expression in prostate cancer cells.

Meng, Alice X; Jalali,Farid; Cuddihy,Andrew; Chan,Norman; Bindra, RanjitS; Glazer, Peter M ...

R01ES005775 Radiother Oncol (2005Aug)

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2005

Hypoxia-induced down-regulation of BRCA1expression by E2Fs.

Bindra, Ranjit S;Gibson, Shannon L;Meng, Alice;Westermark, Ulrica;Jasin, Maria; Pierce, An...


2005

Hypoxia-induced phosphorylation of Chk2 in anataxia telangiectasia mutated-dependent manner.

Gibson, Shannon L;Bindra, Ranjit S;Glazer, Peter M


2005

Importance of chromium-DNA adducts inmutagenicity and toxicity of chromium(VI).

Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2005Jan)

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2005

Killing of chromium-damaged cells by mismatchrepair and its relevance to carcinogenesis.

Zhitkovich, Anatoly;Peterson-Roth,Elizabeth; Reynolds,Mindy

R01ES008786 Cell Cycle (2005 Aug) 15970712

2005

Mismatch repair proteins are activators of toxicresponses to chromium-DNA damage.

Peterson-Roth,Elizabeth; Reynolds,Mindy; Quievryn,George; Zhitkovich,Anatoly

R01ES008786,T32ES007272

Mol Cell Biol (2005 May) 15831465

2005

Saccharomyces cerevisiae MPH1 gene, required forhomologous recombination-mediated mutationavoidanc ...

Prakash, Rohit; Krejci,Lumir; Van Komen,Stephen; Anke Schurer,Kirsten; Kramer,Wilfried; Sun ...

R01ES007061 J Biol Chem (2005 Mar 4) 15634678

2005

Thymoquinone induces apoptosis through activation ofcaspase-8 and mitochondrial events in p53-null ...

El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-En; Wani,Gulzar; Wani, Altaf A

R01ES012991 Int J Cancer (2005 Nov 10) 15906362

2005

Translocation of XRCC1 and DNA ligase IIIalphafrom centrosomes to chromosomes in response toDNA da ...

Okano, Satoshi; Lan, Li;Tomkinson, Alan E;Yasui, Akira


2005

Cell-interdependent cisplatin killing byKu/DNA-dependent protein kinase signalingtransduced throug ...

Jensen, Ryan; Glazer,Peter M


15069205

2004

Depletion of intracellular ascorbate by thecarcinogenic metals nickel and cobalt results in the ind...

Salnikow, Konstantin;Donald, Steven P;Bruick, Richard K;Zhitkovich, Anatoly;Phang, James M; ...


2004

Differential arrangements of conserved buildingblocks among homologs of the Rad50/Mre11 DNArepair ...

de Jager, Martijn;Trujillo, Kelly M; Sung,Patrick; Hopfner,Karl-Peter; Carney,James P; Tain ...

R01ES007061 J Mol Biol (2004 Jun 11) 15165861

2004

Differentiation of DNA reactive and non-reactivegenotoxic mechanisms using gene expression profile...

Dickinson, Donna A;Warnes, Gregory R;Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly; R...

R01ES008786 Mutat Res (2004 May 18) 15120961

2004

Down-regulation of Rad51 and decreased homologousrecombination in hypoxic cancer cells.

Bindra, Ranjit S;Schaffer, Paul J; Meng,Alice; Woo, Jennifer;Måseide, Kårstein;Roth, Matt ...

R01ES005775 Mol Cell Biol (2004 Oct) 15367671

2004

Human nucleotide excision repair efficiently removeschromium-DNA phosphate adducts and protects cel ...

Reynolds, Mindy;Peterson, Elizabeth;Quievryn, George;Zhitkovich, Anatoly

R01ES008786,T32ES007272

J Biol Chem (2004 Jul 16) 15087443

2004

Meiotic recombination: an affair of two recombinases.

Sehorn, Michael G;Sung, Patrick

R01ES007061 Cell Cycle (2004 Nov) 15547324

2004

Multiple interactions with the Rad51 recombinasegovern the homologous recombination function of Rad...

Raschle, Markus; VanKomen, Stephen; Chi,Peter; Ellenberger,Tom; Sung, Patrick

R01ES007061 J Biol Chem (2004 Dec10)

15465810

2004

Physical and functional interaction between theXPF/ERCC1 endonuclease and hRad52.

Motycka, Teresa A;Bessho, Tadayoshi;Post, Sean M; Sung,Patrick; Tomkinson,Alan E


2004

Role of ATP hydrolysis in the antirecombinasefunction of Saccharomyces cerevisiae Srs2 protein.

Krejci, Lumir; Macris,Margaret; Li, Ying; VanKomen, Stephen;Villemain, Jana;Ellenberger, T ...


15047689

2004

Role of the nuclease activity of Saccharomycescerevisiae Mre11 in repair of DNA double-strandbreak ...

Lewis, L Kevin; Storici,Francesca; Van Komen,Stephen; Calero,Shanna; Sung, Patrick;Resnick, ...

R01ES007061 Genetics (2004 Apr) 15126391

2004

UV radiation-induced XPC translocation withinchromatin is mediated by damaged-DNA bindingprotein, ...

Wang, Qi-En; Zhu,Qianzheng; Wani,Gulzar; Chen, Jianming;Wani, Altaf A

R01ES012991 Carcinogenesis (2004 Jun) 14742321

2004

ATPase and DNA helicase activities of theSaccharomyces cerevisiae anti-recombinase Srs2.

Van Komen, Stephen;Reddy, MotheSreedhar; Krejci,Lumir; Klein, Hannah;Sung, Patrick

R01ES007061 J Biol Chem (2003 Nov 7) 12966095

2003

Decreased expression of the DNA mismatch repairgene Mlh1 under hypoxic stress in mammalian cells.

Mihaylova, Valia T;Bindra, Ranjit S; Yuan,Jianling; Campisi,Denise; Narayanan,Latha; Jensen ...

R01ES005775 Mol Cell Biol (2003 May) 12697826

2003

Elevated levels of DNA-protein crosslinks andmicronuclei in peripheral lymphocytes of tanneryworke ...

Medeiros, M G;Rodrigues, A S;Batoréu, M C; Laires,A; Rueff, J; Zhitkovich,A

R01ES008786 Mutagenesis (2003 Jan) 12473731

2003

GATA-4 and GATA-5 transcription factor genes andpotential downstream antitumor target genes are epi ...

Akiyama, Yoshimitsu;Watkins, Neil; Suzuki,Hiromu; Jair,Kam-Wing; vanEngeland, Manon;Estell ...

R01ES011858 Mol Cell Biol (2003 Dec) 14612389

2003

Gene silencing in cancer in association with promoterhypermethylation.

Herman, James G;Baylin, Stephen B

R01ES011858 N Engl J Med (2003 Nov20)

14627790

2003

Genetic control of interconnected neuronal populationsin the mouse primary visual system.

Seecharan, Dave J;Kulkarni, Anand L; Lu,Lu; Rosen, Glenn D;Williams, Robert W

R01ES012991 J Neurosci (2003 Dec 03) 14657177

2003

Genotoxicity and mutagenicity ofchromium(VI)/ascorbate-generated DNA adducts inhuman and bacterial ...

Quievryn, George;Peterson, Elizabeth;Messer, Joseph;Zhitkovich, Anatoly

R01ES008786,T32ES007272

Biochemistry (2003 Feb 4) 12549927

2003

Rad51 recombinase and recombination mediators. Sung, Patrick; Krejci,Lumir; Van Komen,Stephen; Sehorn,Michael G


2003

Yeast xrs2 binds DNA and helps target rad50 andmre11 to DNA ends.

Trujillo, Kelly M; Roh,Dong Hyun; Chen,Ling; Van Komen,Stephen; Tomkinson,Alan; Sung, Patr ...

R01ES007061 J Biol Chem (2003 Dec05)

14522986

2003

Carcinogenic chromium(VI) induces cross-linking ofvitamin C to DNA in vitro and in human lung A549 ...

Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly

R01ES008786 Biochemistry (2002 Mar05)

11863455

2002

Dependence of histone modifications and geneexpression on DNA hypermethylation in cancer.

Fahrner, Jill A; Eguchi,Sayaka; Herman, JamesG; Baylin, Stephen B


2002

Functional cross-talk among Rad51, Rad54, andreplication protein A in heteroduplex DNA jointformat ...

Van Komen, Stephen;Petukhova, Galina;Sigurdsson, Stefan;Sung, Patrick


12226081

2002

Interaction with Rad51 is indispensable forrecombination mediator function of Rad52.

Krejci, Lumir; Song,Binwei; Bussen,Wendy; Rothstein,Rodney; Mortensen,Uffe H; Sung, Patric ...


2002

Reductive activation with cysteine represents achromium(III)-dependent pathway in the induction of...

Zhitkovich, Anatoly;Quievryn, George;Messer, Joseph;Motylevich, Zhanna

R01ES008786 Environ Health Perspect(2002 Oct)

12426121

2002

ATM-dependent expression of the insulin-like growthfactor-I receptor in a pathway regulating radiat ...

Peretz, S; Jensen, R;Baserga, R; Glazer, P M

R01ES005775 Proc Natl Acad Sci U S A(2001 Feb 13)

11172010

2001

Basis for avid homologous DNA strand exchange byhuman Rad51 and RPA.

Sigurdsson, S; Trujillo,K; Song, B; Stratton, S;Sung, P


11124265

2001

DNA pairing and strand exchange by the Escherichiacoli RecA and yeast Rad51 proteins without ATP hy ...

Rice, K P; Eggler, A L;Sung, P; Cox, M M


2001

DNA structure-specific nuclease activities in theSaccharomyces cerevisiae Rad50*Mre11 complex.

Trujillo, K M; Sung, P R01ES007061 J Biol Chem (2001 Sep 21) 11454871

2001

Hypermutability to ionizing radiation in mismatchrepair-deficient, Pms2 knockout mice.

Xu, X S; Narayanan, L;Dunklee, B; Liskay, RM; Glazer, P M

R01ES005775 Cancer Res (2001 May 1) 11325851

2001

Mediator function of the human Rad51B-Rad51Ccomplex in Rad51/RPA-catalyzed DNA strandexchange.

Sigurdsson, S; VanKomen, S; Bussen, W;Schild, D; Albala, J S;Sung, P

R01ES007061 Genes Dev (2001 Dec 15) 11751636

2001

Non-oxidative mechanisms are responsible for theinduction of mutagenesis by reduction of Cr(VI) wit ...

Zhitkovich, A; Song, Y;Quievryn, G; Voitkun,V

R01ES008786 Biochemistry (2001 Jan16)

11148050

2001

Promotion of Dnl4-catalyzed DNA end-joining by theRad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes.

Chen, L; Trujillo, K;Ramos, W; Sung, P;Tomkinson, A E

R01ES007061 Mol Cell (2001 Nov) 11741545

2001

Reduction of Cr (VI) by cysteine: significance inhuman lymphocytes and formation of DNA damage inr ...

Quievryn, G; Goulart,M; Messer, J;Zhitkovich, A

R01ES008786 Mol Cell Biochem (2001Jun)

11678591

2001

Structure of the Rad50 x Mre11 DNA repair complexfrom Saccharomyces cerevisiae by electron microsco...

Anderson, D E; Trujillo,K M; Sung, P;Erickson, H P


2001

Functional interactions among yeast Rad51recombinase, Rad52 mediator, and replication proteinA in ...

Song, B; Sung, P R01ES007061 J Biol Chem (2000 May26)

10748203

2000

Interactions of the DNA ligase IV-XRCC4 complexwith DNA ends and the DNA-dependent proteinkinase.

Chen, L; Trujillo, K;Sung, P; Tomkinson, AE

R01ES007061 J Biol Chem (2000 Aug25)

10854421

2000

Ionizing radiation-induced apoptosis via separatePms2- and p53-dependent pathways.

Zeng, M; Narayanan, L;Xu, X S; Prolla, T A;Liskay, R M; Glazer, PM

R01ES005775 Cancer Res (2000 Sep 1) 10987303

2000

Loss of DNA-protein crosslinks fromformaldehyde-exposed cells occurs throughspontaneous hydrolysis ...

Quievryn, G;Zhitkovich, A

R01ES008786 Carcinogenesis (2000 Aug) 10910961

2000

Mutagenesis in PMS2- and MSH2-deficient miceindicates differential protection from transversions an...

Andrew, S E; Xu, X S;Baross-Francis, A;Narayanan, L;Milhausen, K; Liskay, RM; Jirik, F R; ...

R01ES005775 Carcinogenesis (2000 Jul) 10874005

2000

Promotion of Rad51-dependent D-loop formation byyeast recombination factor Rdh54/Tid1.

Petukhova, G; Sung, P;Klein, H

R01ES007061 Genes Dev (2000 Sep 01) 10970884

2000

Rats retain chromium in tissues following chronicingestion of drinking water containing hexavalent ...

Sutherland, J E;Zhitkovich, A; Kluz, T;Costa, M

R01ES008786 Biol Trace Elem Res (2000Apr)

11049199

2000

Recombination factors of Saccharomyces cerevisiae. Sung, P; Trujillo, K M;Van Komen, S

R01ES007061 Mutat Res (2000 Jun 30) 10915877

2000

Reductive metabolism of Cr(VI) by cysteine leads tothe formation of binary and ternary Cr--DNA addu ...

Zhitkovich, A; Shrager,S; Messer, J

R01ES008786 Chem Res Toxicol (2000Nov)

11087433

2000

Superhelicity-driven homologous DNA pairing byyeast recombination factors Rad51 and Rad54.

Van Komen, S;Petukhova, G;Sigurdsson, S; Stratton,S; Sung, P

R01ES007061 Mol Cell (2000 Sep) 11030336

2000

Analysis of DNA-protein crosslinking activity ofmalondialdehyde in vitro.

Voitkun, V; Zhitkovich,A

R01ES008786 Mutat Res (1999 Mar 08) 10064853

1999

Different mutator phenotypes in Mlh1- versusPms2-deficient mice.

Yao, X; Buermeyer, AB; Narayanan, L; Tran,D; Baker, S M; Prolla,T A; Glazer, P M;Liskay, ...

R01ES005775 Proc Natl Acad Sci U S A(1999 Jun 08)

10359802

1999

Single strand DNA binding and annealing activities inthe yeast recombination factor Rad59.

Petukhova, G; Stratton,S A; Sung, P


10567339

1999

The Tyr-265-to-Cys mutator mutant of DNApolymerase beta induces a mutator phenotype inmouse LN12 c ...

Clairmont, C A;Narayanan, L; Sun, KW; Glazer, P M;Sweasy, J B


10449735

1999

Yeast Rad54 promotes Rad51-dependent homologousDNA pairing via ATP hydrolysis-driven change inDNA ...

Petukhova, G; VanKomen, S; Vergano, S;Klein, H; Sung, P


1999

Cr(III)-mediated crosslinks of glutathione or aminoacids to the DNA phosphate backbone are mutageni ...

Voitkun, V; Zhitkovich,A; Costa, M


9518499 1998

Nuclease activities in a complex of humanrecombination and DNA repair factors Rad50, Mre11,and p95 ...

Trujillo, K M; Yuan, SS; Lee, E Y; Sung, P

R01ES007061 J Biol Chem (1998 Aug21)

9705271 1998

Utilization of DNA-protein cross-links as a biomarkerof chromium exposure.

Zhitkovich, A; Voitkun,V; Kluz, T; Costa, M

R01ES008786 Environ Health Perspect(1998 Aug)

9703480 1998

Elevated levels of mutation in multiple tissues of micedeficient in the DNA mismatch repair gene Pm ...

Narayanan, L; Fritzell, JA; Baker, S M; Liskay,R M; Glazer, P M


9096356 1997

Function of yeast Rad52 protein as a mediator betweenreplication protein A and the Rad51 recombinas ...

Sung, P R01ES007061 J Biol Chem (1997 Nov07)

9353267 1997

Insulin-like growth factor-I receptor overexpressionmediates cellular radioresistance and local bre ...

Turner, B C; Haffty, BG; Narayanan, L; Yuan,J; Havre, P A; Gumbs,A A; Kaplan, L;Burgaud, ...

R01ES005775 Cancer Res (1997 Aug 1) 9242428 1997

Role of DNA mismatch repair in the cytotoxicity ofionizing radiation.

Fritzell, J A; Narayanan,L; Baker, S M; Bronner,C E; Andrew, S E;Prolla, T A; Bradley, A;...

R01ES005775 Cancer Res (1997 Nov 15) 9371516 1997

Yeast Rad55 and Rad57 proteins form a heterodimerthat functions with replication protein A to promo ...

Sung, P R01ES007061 Genes Dev (1997 May 01) 9159392 1997

Dual requirement for the yeast MMS19 gene in DNArepair and RNA polymerase II transcription.

Lauder, S; Bankmann,M; Guzder, S N; Sung,P; Prakash, L; Prakash,S

R01ES007061 Mol Cell Biol (1996 Dec) 8943333 1996

Frequent spontaneous deletions at a shuttle vectorlocus in transgenic mice.

Leach, E G; Gunther, EJ; Yeasky, T M;Gibson, L H;Yang-Feng, T L;Glazer, P M

R01ES005775 Mutagenesis (1996 Jan) 8671715 1996

Genetic instability induced by the tumormicroenvironment.

Reynolds, T Y;Rockwell, S; Glazer, PM

R01ES005775 Cancer Res (1996 Dec 15) 8971187 1996

Mutagenesis by third-strand-directed psoralen adductsin repair-deficient human cells: high frequenc ...

Raha, M; Wang, G;Seidman, M M; Glazer,P M


8610147 1996

Mutagenesis in mammalian cells induced by triplehelix formation and transcription-coupled repair.

Wang, G; Seidman, MM; Glazer, P M

R01ES005775 Science (1996 Feb 09) 8628995 1996

Recombination induced by triple-helix-targeted DNAdamage in mammalian cells.

Faruqi, A F; Seidman,M M; Segal, D J;Carroll, D; Glazer, P M

R01ES005775 Mol Cell Biol (1996 Dec) 8943337 1996

Targeted mutagenesis mediated by the triple helixformation.

Glazer, P M; Wang, G;Havre, P A; Gunther, EJ

R01ES005775 Methods Mol Biol (1996) 8849999 1996

Tissue specificity of spontaneous point mutations inlambda supF transgenic mice.

Leach, E G; Narayanan,L; Havre, P A; Gunther,E J; Yeasky, T M;Glazer, P M

R01ES005775 Environ Mol Mutagen(1996)

8991078 1996

Yeast Rad51 recombinase mediates polar DNA strandexchange in the absence of ATP hydrolysis.

Sung, P; Stratton, S A R01ES007061 J Biol Chem (1996 Nov08)

8910403 1996

Altered repair of targeted psoralen photoadducts in thecontext of an oligonucleotide-mediated tripl ...

Wang, G; Glazer, P M R01ES005775 J Biol Chem (1995 Sep 22) 7673252 1995

DNA strand exchange mediated by a RAD51-ssDNAnucleoprotein filament with polarity opposite to that ...

Sung, P; Robberson, DL

R01ES007061 Cell (1995 Aug 11) 7634335 1995

G:C transversions in X-irradiated mouse cells.">Frequent T:A-->G:C transversions in X-irradiatedmouse cells.

Yuan, J; Yeasky, T M;Rhee, M C; Glazer, P M

R01ES005775 Carcinogenesis (1995 Jan) 7834808 1995

Induction of p53 in mouse cells decreases mutagenesisby UV radiation.

Yuan, J; Yeasky, T M;Havre, P A; Glazer, P M

R01ES005775 Carcinogenesis (1995 Oct) 7586125 1995

Mutagenesis by 8-methoxypsoralen and5-methylangelicin photoadducts in mouse fibroblasts:mutations ...

Gunther, E J; Yeasky, TM; Gasparro, F P;Glazer, P M

R01ES005775 Cancer Res (1995 Mar 15) 7882323 1995

Targeted mutagenesis in mammalian cells mediated byintracellular triple helix formation.

Wang, G; Levy, D D;Seidman, M M; Glazer,P M

R01ES005775 Mol Cell Biol (1995 Mar) 7862165 1995

Site-specific targeting of psoralen photoadducts with atriple helix-forming oligonucleotide: charac ...

Gasparro, F P; Havre, PA; Olack, G A;Gunther, E J; Glazer, PM

R01ES005775 Nucleic Acids Res (1994Jul 25)

8052539 1994

High efficiency, restriction-deficient in vitro packagingextracts for bacteriophage lambda DNA usin ...

Gunther, E J; Murray, NE; Glazer, P M

R01ES005775 Nucleic Acids Res (1993Aug 11)

8396240 1993

Targeted mutagenesis of DNA using triplehelix-forming oligonucleotides linked to psoralen.

Havre, P A; Gunther, EJ; Gasparro, F P; Glazer,P M


8356097 1993

Targeted mutagenesis of simian virus 40 DNAmediated by a triple helix-forming oligonucleotide.

Havre, P A; Glazer, P M R01ES005775 J Virol (1993 Dec) 8230456 1993

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