Tinnitusbook
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G. Attanasio (a,f), P. Ciccarese (b,c), E. Wu (e), T. Clark (b,c,d), E. Pecis (f), R. Filipo(a) a: Dept. Neurology and Otolaryngology, University La Sapienza, Rome, IT; b: Massachusetts Gen. Hosp., Boston, MA; c: Harvard Med. School, Boston, MA; d: Harvard Initiative in Innovative Computing, Cambridge, MA; e: Alzheimer Res. Forum Found., Boston, MA; f: Acufeni.net Association onlus 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research
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A crucial new interdisciplinary resource for Tinnitus researchers
Transcript of Tinnitusbook
G. Attanasio (a,f), P. Ciccarese (b,c), E. Wu (e), T. Clark (b,c,d), E. Pecis (f), R. Filipo(a)
a: Dept. Neurology and Otolaryngology, University La Sapienza, Rome, IT; b: Massachusetts Gen. Hosp., Boston, MA; c: Harvard Med. School, Boston, MA; d: Harvard Initiative in Innovative Computing, Cambridge, MA; e: Alzheimer Res. Forum Found., Boston, MA; f: Acufeni.net Association onlus
3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy
Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research
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OUR PROJECT
COMMUNITY OF PATIENTS
COMMUNITY OF SCIENTISTS
To create a new interdisciplinary online resource connecting researchers with
researchers, to facilitate rapid progress in Tinnitus research
Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research
Paolo Ciccarese, PhDMass General Hospital / Harvard Medical School
Building Online Communities for Scientists
3rd Tinnitus Research Initiative Meeting
24-26 June 2009, Stresa, Italy
In collaboration with Alzheimer Research Forum
Alzheimer Research Forum
• Created in 1996 www.alzforum.org• 58,000 Alzheimer Disease (AD) Related
Papers• 1800 AD Related News Articles• Curated 14,700 Antibodies• 5000 Members (AD Scientists)• 6300 Scientists’ Comments• Over 80 live discussions
> The CNN of Alzheimer
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Alzheimer Research Forum
58,000 AD Related Papers
6300 Scientists’ Comments
Over 80 Live Discussions
ARF - People
• Executive Editor (June Kinoshita)• 2 Managing Editors• 3 Science Writers• 3 Consultants (Elizabeth Wu for Knowledge Managment)• 1 Drug Database Curator (Gwen Wong, PhD)• 1 Event Coordinator• 1 Web Developer• 1 Production Assistant• 10 Advisory Board
…and 5000 Scientists!!!
SWAN - Semantic Web Applications in Neuromedicine
• Define Hypotheses, Claims, Research Questions, Comments, Experiments– To relate them in between each others – To relate them to Gene, Protein, Antibodies,
Organisms• Annotate Publications (manual and semi-
automatic)• Efficient browsing of the knowledge base• Knowledge sharing across communities
SWAN Model
SWAN Homepageht
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SWAN Hypotheses
SWAN Hypothesis
SWAN Claim
Qualifiers
SupportiveEvidence
Relationships with other statements in the KB
Lses
SWAN Graph [1]
SWAN Graph [2]
SWAN Graph [3]
Schizophrenia Research Forum
High Number of Resources
• PubMed• Mash Terminology• Entrez Gene• UniProt• Gene Ontology• Alzforum Gene• Alzforum Antibodies• Experimental Data
• Reagents• Experiments• Neuro Imaging• Models• Annotations• Discussions• Commentaries• …
Science Collaboration Framework
• Reusable software that can be used to develop web-based, collaborative, scientific communities
• Support interdisciplinary scientists in publishing, annotating, sharing and discussing content such as articles, perspectives, interviews and news items, as well as assert personal biographies and research interests
stembook.org
stembook.org
• It is an open access collection of invited, original, peer-reviewed chapters (46 a few days ago) covering a range of topics related to stem cell biology written by top researchers in the field at the Harvard Stem Cell Institute and worldwide.
• ISSN 1940-3429
Table of Contents
Example: Link to genes
Other Stem Book features
• eAlert• Commenting and discussion forums• Semiautomatic annotation of Genes in new
articles• Access to the under-development clouds of
resources for life science (genes, proteins, antibodies, organisms…)
PDonline.org
What we can offer
• Experience in creating and maintain online communities
• Reusable software that can speed up the process of creation of a new community
• Access to biomedical knowledge bases• Access to new methods and technologies
as result of our research• Be part of a community of communities
Thank you
• Tim Clark• Gwen Wong• June Kinoshita• Marco Ocana• Elizabeth Wu
• Sudeshna Das• Benjamin Melançon
Paolo Ciccarese, PhD
