Thursday, October 2, 2014

Title: Genetic DisordersLT: I will be able to explain the inheritance

of various genetic disorders.Do Now:

1. What is the difference between an autosomal disorder and a sex linked disorder?

2. Analyze the pedigree below and answer the following:

The characteristic indicated by the blackened figures is probably: a. Dominant. b. Recessive. c. Non-dominant. d. Sex-linked recessive.

Pedigree Question #1 to Ask…

• What is the mode of inheritance?– Autosomal dominant: the disorder is a dominant trait, only one affected allele must be inherited to show the phenotype

– Autosomal recessive: the disorder is a recessive trait and offspring must inherit TWO recessive alleles to show the phenotype

– Sex Linked: the disorder is LINKED to the X chromosome and is inherited when the affected X or two affected X chromosomes are passed on

How do I Know???

Autosomal DOMINANT

Autosomal Dominant Disorders:

• Affects males and females equally

• Both genders can pass the trait• Later generations will be affected

• Rarely skips a generation– Achondroplasia (dwarfism)– Huntington’s Disease– Marfan Disease

How do I Know???

Sex Linked Disorder

Sex Linked Disorders

• Affects males more than females• Only females can be carriers• Can be passed from either parent*

• Most are recessive–Duchenne Muscular Dystrophy–Colorblindness–Hemophilia

How do I Know???

Autosomal RECESSIVE

Autosomal Recessive Disorders

• Affects both genders equally• Can skip generations• Both genders can be carriers–Cystic Fibrosis–Sickle Cell Anemia–Tay-Sachs

Today’s Activity:

• You and a partner will research ONE inherited genetic disorder.

• You will use that research to identify FIVE FAST FACTS about the disorder.

• You will then read a scenario about a family that has a history of that disorder.

• Using the scenario, you will create a pedigree that accurately represents the family history of that disorder.

• You will then answer the questions posed.• Your final assessment of mastery will be a POSTER and PRESENTATION* of that poster to the class.

Poster Requirements:

• Disorder Name: BOLD, NEAT, CLEAR

• Five Facts• Pedigree: CORRECT, CLEAR, NEAT

• @ least ONE Punnett Square you ran

• Scenario attached*My walls are bare… I’d like to change that!

Thursday, October 2, 2014

Title: Pedigrees and Genetic Disorders

LT: I will be able to trace the inheritance of a trait within a

family.

Do Now: Why would it be important to be

able to track the inheritance of a trait across multiple generations

of a family?

Today’s Agenda

1.You will record live notes about PEDIGREES and GENETIC DISORDERS.

2.You will receive a practice worksheet about pedigrees to complete as homework, DUE tomorrow.

Friday, October 3, 2014

• Do Now: Using the pedigree, determine which mode of inheritance (autosomal dominant, autosomal recessive, sex linked) the trait follows. Explain your choice. Then, determine the genotype of person X.

LT: I will be able to track the inheritance of a trait within multiple generations of a family using a pedigree.

Today’s Agenda1.You will continue your genetic investigation of a family history and a genetic disorder.

2.DUE at END of class:1.Completed poster2.Don’t forget to turn in your

purple pedigree homework!

Friday, October 3, 2014

• Do Now: DRAW THE PEDIGREE!

• Using the pedigree, determine:– What is the relationship between U, V and W?

– What is the phenotype of X?

– What is the genotype of Y?

Title: Pedigrees – Mode of InheritanceLT: I will be able to track the inheritance of a trait within multiple generations of a family using a pedigree.

Today’s Agenda1.You will record quick notes about PEDIGREES and GENETIC DISORDERS.

2.You will work with your lab group to create a pedigree about a family and their history of a genetic disorder.

3.Don’t forget!!! Turn in your pedigree homework from last night!

Pedigree Question #1 to Ask…

• What is the mode of inheritance?– Autosomal dominant: the disorder is a dominant trait, only one affected allele must be inherited to show the phenotype

– Autosomal recessive: the disorder is a recessive trait and offspring must inherit TWO recessive alleles to show the phenotype

– Sex Linked: the disorder is LINKED to the X chromosome and is inherited when the affected X or two affected X chromosomes are passed on

How do I Know???

Autosomal DOMINANT

Autosomal Dominant Disorders:

• Affects males and females equally

• Both genders can pass the trait• Later generations will be affected

• Rarely skips a generation– Achondroplasia (dwarfism)– Huntington’s Disease– Marfan Disease

How do I Know???

Sex Linked Disorder

Sex Linked Disorders

• Affects males more than females• Only females can be carriers• Can be passed from either parent*

• Most are recessive–Duchenne Muscular Dystrophy–Colorblindness–Hemophilia

How do I Know???

Autosomal RECESSIVE

Autosomal Recessive Disorders

• Affects both genders equally• Can skip generations• Both genders can be carriers–Cystic Fibrosis–Sickle Cell Anemia–Tay-Sachs