This inaugural interdisciplinary event is an open forum for discussion of the processes involved in wound healing, recent advances in its research

and therapies related to wound healing and infection. Using a multi-professional and inter-specialty approach, and an international setting, this event promises plenty of opportunity for discussion and debate set

in an informal atmosphere.

This event has CPD accreditation

www.WoundHealing2016.com

#Wound16

Contents AGENDA ................................................................................................................................................................ 5

Day 1: Management of Infections ............................................................................................................ 5

Introduction by the Chair ...................................................................................................................................... 5

Biofilms: A Paradigm Shift in Wound Microbiology .............................................................................................. 5

Mechanism of wound repair in gastrointestinal tract .......................................................................................... 5

Oral Presentations ................................................................................................................................................ 5

MANAGEMENT OF DIABETIC FOOT HEALING: EXPERIENCE OF THE NATIONAL CENTRE OF BURNS AND PLASTIC

SURGERY: MOROCCO ............................................................................................................................................ 5

BIOLOGICAL AND MICROBIOLOGICAL IMPACT OF PLASMA MEDICINE IN WOUND HEALING ............................. 5

Development of novel wound dressings for infection control: exploration of infection-responsive release and

prophylactic bacteriophage therapy ..................................................................................................................... 5

Oral presentation ................................................................................................... Error! Bookmark not defined.

TBC ......................................................................................................................... Error! Bookmark not defined.

TBC ......................................................................................................................... Error! Bookmark not defined.

Periodontal wound healing and its enhancement by application of lasers .......................................................... 5

Question Time ....................................................................................................................................................... 5

AGENDA ................................................................................................................................................................ 6

Day 2: Session 1: Stem Cells and Regeneration ....................................................................................... 6

Introduction by the Chair ...................................................................................................................................... 6

Roles of Mesenchymal Stem Cells in Cutaneous Wound Healing ........................................................................ 6

Group Photo and Session Break ............................................................................................................................ 6

Oral Presentation .................................................................................................................................................. 6

RESULTS OF THE INTERIM ANALYSIS OF THE SAWHI-V.A.C.-STUDY ..................................................................... 6

SUB MOLECULAR ASPECT OF TYROSINE KINASE MEDIATED MUCOSAL WOUND REPAIR.................................... 6

Question Time ....................................................................................................................................................... 6

Session Break ........................................................................................................................................................ 6

Session 2: Stimulating Wound Healing ...................................................................................................... 6

Introduction by the Chair ...................................................................................................................................... 6

Exploiting inherited genetic models to dissect the STAT3/HIF1alpha signalling axis, a key driver of cell

migration and invasion.......................................................................................................................................... 6

Enhanced Wound Healing with Copper Oxide Impregnated Dressings - Molecular Mechanisms ....................... 6

Session Break ........................................................................................................................................................ 6

Reactive Oxygen and Wounds- from the Laboratory to the Labour Ward ........................................................... 6

Question Time ....................................................................................................................................................... 6

Chairman’s Summing Up ....................................................................................................................................... 6

AGENDA ................................................................................................................................................................ 7

Day 3: Fibroblasts and Myofibroblasts .................................................................................................... 7

Introduction by the Chair ...................................................................................................................................... 7

Extracellular PKM2 facilitates wound healing by promoting myofibroblast differentiation and angiogenesis ... 7

Oral Presentations ................................................................................................................................................ 7

THE ROLE OF FIBROBLASTS AND TGF-β (Transforming Growth Factor beta) ON WOUND HEALING:

HYPERTROPHIC AND KELOID SCARS ..................................................................................................................... 7

ANALYSIS OF POLYMICROBIAL BIOFILM INFECTIONS IN NON HEALING DIABETIC ULCER ................................... 7

Question Time ....................................................................................................................................................... 7

The role of the hair follicle in cutaneous wound healing ..................................................................................... 7

About the Speakers ...............................................................................................................................................8

Diana Alves, ........................................................................................................................................................... 8

Águeda Sena Carvalho, ......................................................................................................................................... 8

Keith Cutting, ........................................................................................................................................................ 8

Radko Chmurovic, ................................................................................................................................................. 8

Moyassar Al-Shaibani, ........................................................................................................................................... 8

Rafik Amine, .......................................................................................................................................................... 9

Gadi Borkow, ......................................................................................................................................................... 9

Jonathan Cooke ..................................................................................................................................................... 9

Narendra Kumar, ................................................................................................................................................... 9

Zhi-Ren Liu, ............................................................................................................................................................ 9

Jayshree Mishra, ................................................................................................................................................. 10

Steven Percival, ................................................................................................................................................... 10

Doerthe Seidel, .................................................................................................................................................... 10

Karthika S, ........................................................................................................................................................... 10

Andrew R. Tee, .................................................................................................................................................... 10

M Julie Thornton, ................................................................................................................................................ 10

ABOUT THIS EVENT ............................................................................................................................................. 11

FREQUENTLY ASKED QUESTIONS ABOUT OUR EVENTS ...................................................................................... 12

AGENDA PLEASE NOTE: DUE TO SECURITY CONTROLS, THERE IS NO ACCESS TO THE VENUE BEFORE 9AM

(Invited Talk times include 5 – 10 minutes for question; Oral presentations include 2-3 minutes for questions)

Day 1: Management of Infections

09:00 – 09:45 Exhibitions open Registration and Refreshments 09:45 – 10:35 Introduction by the Chair

Biofilms: A Paradigm Shift in Wound Microbiology

Professor Steven Percival, 5D Health Protection Group Ltd and University of Liverpool, UK

10:35 – 11:15 Mechanism of wound repair in gastrointestinal tract

Dr. Narendra Kumar, Associate Professor (Tenured), Department of Pharmaceutical Sciences, TX, USA

11:15 – 11:45 Group Photo and Session Break

Refreshments, Poster viewing, Sponsors exhibition

11:45 – 12:25 Oral Presentations 11:45 – 12:05 MANAGEMENT OF DIABETIC FOOT

HEALING: EXPERIENCE OF THE NATIONAL CENTRE OF BURNS AND PLASTIC SURGERY: MOROCCO

Dr Rafik Amine, Resident in Plastic surgery, National Center for Burns and Plastic Surgery, Casablanca, Morocco

12:05 – 12:25 BIOLOGICAL AND MICROBIOLOGICAL IMPACT OF PLASMA MEDICINE IN WOUND HEALING

Keith Cutting, Clinical Research Consultant, Hertfordshire, UK

12:25 – 13:05 Development of novel wound dressings for infection control: exploration of infection-responsive release and prophylactic bacteriophage therapy

Dr Diana Alves, School of Pharmacy and Biomolecular Sciences, Univeristy of Brighton / Blond McIndoe Research Foundation, Brighton UK

13:05 – 14:05 Session Break Lunch, Poster viewing, Sponsors exhibition

14:05 – 14:45 Periodontal wound healing and its enhancement by application of lasers

Radko Chmurovic, Wise Dental Ltd, Nottingham, UK

14:45 – 15:30 Question Time

15:30 Chairman’s Summing Up Close of Session

PLEASE NOTE TIMINGS ARE SUBJECT TO CHANGE

AGENDA (Invited Talk times include 5 – 10 minutes for question; Oral presentations include 2-3 minutes for questions)

Day 2: Session 1: Stem Cells and Regeneration

09:00 – 09:45 Exhibitions open Registration and Refreshments 09:45 – 10:00 Introduction by the Chair Dr. Narendra Kumar, Associate Professor

(Tenured), Department of Pharmaceutical Sciences, TX, USA

10:00 – 10:40 Roles of Mesenchymal Stem Cells in Cutaneous Wound Healing

Moyassar Al-Shaibani, Institute of Cellular Medicine, The Faculty of Medical Sciences, Ground Floor William Leech Building, Newcastle University, Framlington, Newcastle upon Tyne, UK

10:40 – 11:10 Group Photo and Session Break Refreshments, Poster viewing, Sponsors exhibition

11:10 – 11:50 Oral Presentation

11:10 – 11:30 RESULTS OF THE INTERIM ANALYSIS OF THE SAWHI-V.A.C.-STUDY

Doerthe Seidel, Institute for Research in Operative Medicine (IFOM), University of Witten / Herdecke, Koeln, Germany

11:30 – 11:50 SUB MOLECULAR ASPECT OF TYROSINE KINASE MEDIATED MUCOSAL WOUND REPAIR

Dr Jayshree Mishra, Research Assistant Professor, Texas A&M University, Kingsville, United States

11:50 – 12:30 Question Time 12:30 – 13:30 Session Break Lunch, Poster viewing Sponsors exhibition

Session 2: Stimulating Wound Healing 13:30 – 14:15 Introduction by the Chair

Exploiting inherited genetic models to dissect the STAT3/HIF1alpha signalling axis, a key driver of cell migration and invasion

Dr Andrew R. Tee, Senior Lecturer in Cancer Genetics, Cardiff University, Cardiff, UK

14:15 – 15:55 Enhanced Wound Healing with Copper Oxide Impregnated Dressings - Molecular Mechanisms

Dr Gadi Borkow, Cupron Inc., Israel

14:55 – 15:25 Session Break Refreshments, Last poster viewing, Last Sponsors exhibition

15:25 – 16:05 Reactive Oxygen and Wounds- from the Laboratory to the Labour Ward

Professor Jonathan Cooke MPharm, PhD, Visiting Professor in the Infectious Diseases and Immunity Section, Department of Medicine, Imperial College London, London, UK

16:05 – 17:00 Question Time

17:00 Chairman’s Summing Up Close of Session

PLEASE NOTE TIMINGS ARE SUBJECT TO CHANGE

AGENDA (Invited Talk times include 5 – 10 minutes for question; Oral presentations include 2-3 minutes for questions)

Day 3: Fibroblasts and Myofibroblasts 09:00 – 09:45 Exhibitions open Registration and Refreshments 09:45 – 10:40 Introduction by the Chair

Extracellular PKM2 facilitates wound healing by promoting myofibroblast differentiation and angiogenesis

Dr Zhi-Ren Liu, Georgia State University, USA

10:40 – 11:10 Group Photo and Session Break

Refreshments, Poster viewing, Sponsors exhibition

11:10 – 11:50 Oral Presentations

11:10 – 11:30 THE ROLE OF FIBROBLASTS AND TGF-β (Transforming Growth Factor beta) ON WOUND HEALING: HYPERTROPHIC AND KELOID SCARS

Águeda Sena Carvalho, Faculty of Medicine University of Porto, Porto, Portugal

11:30 – 11:50 ANALYSIS OF POLYMICROBIAL BIOFILM INFECTIONS IN NON HEALING DIABETIC ULCER

Karthika S, Cholera and Biofilm Research Laboratory, Rajiv Gandhi Centre for Biotechnology, Kerala, India

11:50 – 12:30 Question Time 12:30 – 13:30 Session Break

Lunch, Poster viewing Sponsors exhibition

13:30 – 14:10 The role of the hair follicle in cutaneous wound healing

Dr M Julie Thornton, Centre for Skin Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK

14:10 Chairman’s Summing Up Close of Event, Refreshments available PLEASE NOTE TIMINGS ARE SUBJECT TO CHANGE

About the Speakers Diana Alves, School of Pharmacy and Biomolecular Sciences, Univeristy of Brighton / Blond McIndoe Research Foundation, Brighton UK Dr Diana R. Alves, is a bacteriophage biologist that recently finished her PhD in the Biophysical Chemistry Research Group in the University of Bath (UK). She has been focus in developing and characterising responsive polyvalent bacteriophage therapeutics, particularly for the treatment of biofilm infections, mainly caused by Staphylococcus aureus and Pseudomonas aeruginosa clinical strains. Her main target is the disruption of biofilms, frequently observed in burn and chronic wounds. She has been working in closely with groups developing smart wound dressings where development of a triggered released of therapeutic bacteriophages when infection in the wound takes place. Hence, she is highly interested in assessing systems to stabilise and deliver the bacteriophage to the site of infection. Águeda Sena Carvalho, Faculty of Medicine University of Porto, Porto, Portugal 1. Doctor from the Faculty of Medicine of Angola; Specialist in Plastic and reconstructive surgery by the Portuguese Doctors and member of the Portuguese Society of Plastic Reconstructive and Aesthetic Surgery. 2. PhD student(fellow) from the Faculty Medicine University of Porto, Portugal, in the area of oncology and molecular biology: Model in skin scarring dysmorphia . Hospital Assistant in Plastic Surgery .Clinical activity currently between northern Portugal: Real CHTMAD -Vila and Luanda, Angola in Clinical Sunflower and Maria Pia Hospital / Josina Macheland Surgery Reconstructive and Aesthetic . Keith Cutting, Clinical Research Consultant, Hertfordshire, UK Keith has been involved in tissue viability for over 25 years and has presented his work nationally and international at conferences that include the WUWHS, EWMA, ETRS and SAWC. He has over 130 peer-reviewed publications in journals, book chapters and conference abstracts. He has a particular interest in diagnosis and management of wound infection and his paper Criteria for wound Infection (JWC 1994) remains the most widely cited paper on clinical criteria for wound infection. Keith is a reviewer for a number of journals and works with a number of medical device and biotech companies as an independent consultant. Radko Chmurovic, Wise Dental Ltd, Nottingham, UK Radko Chmurovic graduated in 1998 from the University of Paul Josef Safarik in Kosice, Slovakia as a Doctor of General Medicine. In 2001 he completed his specialisation as a general dentist and was awarded Postgradual Diploma by Slovak Postgraduate Academy of Medicine. In 2006 he relocated to UK and subsequently achieved Postgraduate Certificate in Clinical Periodontology from the University of Central Lancashire (2009), Master in Clinical Dentistry in Periodontology from the University of Sheffield (2012), Master in Implant dentistry from the University of Warwick (2012) and recognition as Specialist in Periodontics by General Dental Council (2014). He practices in Nottingham. Moyassar Al-Shaibani, Institute of Cellular Medicine, The Faculty of Medical Sciences, Ground Floor William Leech Building, Newcastle University, Framlington, Newcastle upon Tyne, UK Education: 2014-Present: PhD student: Institute of Cellular Medicine, The Faculty of Medical Sciences, Newcastle University, UK. 2004-2007: MSc Biotechnology, Al-Nahrain University, Iraq. 2001-2004: BSc Biotechnology, Al-Nahrain University, Iraq. Emloyment (Morning): 2007-2013: Lecturer / Biotechnology Dept., School of Sciences, Al-Nahrain University. Iraq. Emloyment (Afternoon): 2011-2013: ABDULMAJEED HUSSEIN Private Hospital / Clinical Laboratory (Technician), Iraq. 2007-2011: JENIN Private Hospital / Clinical Laboratory (Technician), Iraq. Resaerch Interest He is interested in studying stem cells and their therapeutic applications. Currently, his researches are focusing on role of MSCs in wound healing and tissue regeneration.

Rafik Amine, Resident in Plastic surgery, National Center for Burns and Plastic Surgery, Casablanca, Morocco I m resident in National center of burns and plastic surgery in Moroco, and i m researcher in woud healing. Gadi Borkow, Cupron Inc., Israel Dr. Gadi Borkow obtained his Ph.D. degree on Biochemistry from the Tel Aviv University, Israel on 1994. His post-doctoral studies were conducted at McGill University AIDS Centre, during which he specialized on Human Immunodeficiency Virus Type 1 (HIV-1). In 1998 Dr. Borkow joined the Hebrew University Institute of Immunology and AIDS Center, where he studied virological and immunological aspects of HIV-1 infection. Since 2002 Dr. Borkow is the Chief Medical Scientist of Cupron Inc. Dr. Borkow serves in the Editorial Board of several scientific journals. Dr. Borkow published over 100 peer reviewed manuscripts. Jonathan Cooke MPharm, PhD, Visiting Professor in the Infectious Diseases and Immunity Section, Department of Medicine, Imperial College London, London, UK Professor Jonathan Cooke has spent over 30 years in the NHS as a senior clinician including the position of Director of Research and Development at the University Hospital of South Manchester. He is visiting Professor, Division of Infectious Diseases, Department of Medicine, Imperial College London and Honorary Professor, Faculty of Medical and Human Sciences, University of Manchester. He has a specialist interest in antimicrobial resistance and was a Member of the UK Department of Health’s Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection (ARHAI) and Chair of the Antimicrobial Stewardship Committee as well as Advisor to the World Health Organisation European Office. He was a Member of the DH Clostridium difficile Guidelines Working Party. He is a Trustee and Director of the Fungal Infection Trust, a registered UK charity. He is author to over 150 peer reviewed publications and reviews and chapters of standard textbooks, has presented over 200 international and national keynote presentations and lectures at major conferences and has received a number of national and international awards Narendra Kumar, Associate Professor (Tenured), Department of Pharmaceutical Sciences, TX, USA Dr. Narendra Kumar completed his PhD in Biotechnology and postdoctoral training in gastrointestinal physiology. Currently he holds the position of Associate Professor with tenure at the Texas A&M Health Science Center. Rated among top 25% in the college by the students, he teaches immunology, biochemistry, and pharmacogenomics/oncology under the professional Pharm.D. program. In research he has received several awards of national and international repute including the Crohn’s and Colitis Foundation of America (CCFA) Research Fellowship Award, CCFA Career Development Award, National Institute of Health (NIH) Basic Scientist Career Development Award (K01), American Gastroenterology Association (AGA) Research Scholar Award to name a few. His research is currently funded by two NIH grants. He has published several peer reviewed research articles, abstracts, book chapters and has multiple patent (either commercialized) or under collaboration for licensing through the NIH –SBIR award. Zhi-Ren Liu, Georgia State University, USA Dr. Zhi-Ren Liu received his Ph.D degree in biochemistry from Department of Chemistry at Florida State University in 1994. After finishing his doctorate, Dr. Liu joined the research group lead by Dr. C. W. J. Smith in Department of Biochemistry, University of Cambridge, UK. His main research topic was to elucidate the molecular mechanism of the spliceosome assembly. In 1999, Dr. Liu joined the faculty in the department of animal science at Auburn University where his research group focused on studying the role of p68 RNA helicase in the pre-mRNA splicing process. He moved his research laboratory to the department of Biology at Georgia State University, Atlanta, 2003 where he is a professor of Cancer Biology. He was awarded as Georgia Cancer Coalition distinguished scholar. He was also named as prestigues distingushed University Professor, 2014. At GSU, Dr. Liu’s laboratory is interested in understanding the molecular mechanism that governs cell developmental program, especially abnormal cell development and cell proliferation that associated with many disease conditions.

Jayshree Mishra, Research Assistant Professor, Texas A&M University, Kingsville, United States Dr. Jayshree Mishra is currently hold an academic rank of Research Assistant Professor at Texas A&M University, Texas. She has published several papers in the reputed peer review journals, book chapters, and also the recipient of several awards and honors of national and international repute such as DAAD Fellowship from Government of Federal Republic of Germany, Jawaharlal Nehru Memorial Fund Award; India, ACCP-TAP Pharmaceuticals GI Investigator Development Research Award from ACCP Research Institute (2006). Currently she is the Co-Principal Investigator of NIH-SBIR funded project. She has a long time experience working in mucosal inflammation; especially finding therapeutic targets to regulate mucosal inflammation. Steven Percival, 5D Health Protection Group Ltd and University of Liverpool, UK Steven holds a PhD in microbiology and biofilms, a PGCE, a diploma in Business Administration, and MSc’s in Public Health and Medical Microbiology. Early in his career Steven held senior R&D positions at North West Water, Phenomenex, The British Textile Technology Group and senior lectureships at numerous universities. In the last 15 years Steven has held the positions of Chief Scientific Officer and Vice President of R&D at numerous SME and global multinational organisations. He has written over 400 scientific publications and provided over 150 presentations world-wide. In 2015 Steven joined the 5D Health Protection Group Ltd as Group Director of Operations and R&D and later the position of CEO. Steven also holds an honorary Professor at The University of Liverpool awarded in 2012. Doerthe Seidel, Institute for Reasearch in Operative Medicine (IFOM), University of Witten / Herdecke, Koeln, Germany Dörthe Seidel is a medical doctor and researcher at the Institute for Research in Operative Medicine of the University of Witten / Herdecke. She is the head of the department for clinical research and has a special focus on wound healing and medical devices. Since 2010 she is the coordinating investigator of two multicentre randomised clinical trials comparing negative pressure wound therapy with the methods of standard conventional wound therapy of the clinical routine. Karthika S, Cholera and Biofilm Research Laboratory, Rajiv Gandhi Centre for Biotechnology, Kerala, India Karthika S is a PhD student working in Rajiv Gandhi Centre for Biotechnology (a national Institute under Govt. of India.) Her research focuses on polymicrobial biofilms associated with chronic diabetic ulcer. She is primarily interested on studying the wound microbiome and the biofilm mode of infection. She is also focusing on identifying genes/pathways specific to biofilm stage via proteomic/ gene expression analysis and main interest is to come up with a broad spectrum antibiofilm agent to promote wound healing. Andrew R. Tee, Senior Lecturer in Cancer Genetics, Cardiff University, Cardiff, UK Dr. Andrew Tee was scientifically trained at Dundee and Harvard University, where his main research strength is with uncovering new cell signalling mechanisms linked to mammalian target of rapamycin (mTOR). To discover and characterise novel signalling mechanisms involved in human disease, he employs genetic models, such as Tuberous Sclerosis Complex (TSC), Birt-Hogg-Dube and Neurofibromatosis type 1 (NF1) at Cardiff University. Andrew research laboratory has expertise in dissecting new signalling mechanisms linked to mTOR, Rheb, TSC, HIF, STAT3, ULK1 and FLCN, and also has a specific interest in autophagy as well as events that drive cancer progression and metastasis. M Julie Thornton, Centre for Skin Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK Julie Thornton PhD is a Faculty Member of the Centre for Skin Sciences at the University of Bradford, UK. She has worked in the field of skin and hair follicle biology with a particular interest the effects of the sex steroids oestrogens and androgens, and their impact in on skin aging, especially in postmenopausal women for a number of years. A long standing collaboration with the Plastic Surgery and Burns Research Unit in Bradford has led to a specific interest in hormones and wound healing, with a strong emphasis on the role of the mesenchymal elements of the hair follicle.

ABOUT THIS EVENT

Discussion Sessions

The discussion sessions are an opportunity for informal questions and answers. This is an ideal opportunity to get advice and opinion from experts in this area. This session is not for questions about specific talks, which can be asked after the speaker’s session, but for discussing either general topics or specific issues. There are three ways you can ask questions: 1. Before the session you can submit your question to Euroscicon staff at the registration desk, 2. Before and during the session you can submit a question or comments, by email, which will be provided on the day of the event 3. During the session you can put your hand up and join in

Session breaks

All breaks and registrations will take place in the exhibition area where there will be lunch and refreshments. Please try to visit all the exhibition stands during this event. Not only do our sponsors enable Euroscicon to keep the registration fees competitive, but they are also here specifically to talk to you

Lunch

All the chicken in our lunch buffet is Halal

We have a number of dishes that are gluten free

We have a range of vegetarian dishes which are separated from the meat and fish dishes

We have a number of dishes that are dairy free

Please note that all food has been prepared in an environment where nuts may be present.

Missing Speakers

It is unfortunate that occasionally a speaker cannot attend, most usually due to not getting visas granted, unforeseen personal events or illness. Whilst we do everything possible to ensure that our speakers are present at the event we apologise in advance if you were at a session where a speaker could not attend. We always try to keep our agendas as up to date as possible, however if a speaker cancels the night before an event or on the day, there is little we can do to rectify this.

FREQUENTLY ASKED QUESTIONS ABOUT OUR EVENTS

Is the delegate list available?

Yes this is available to everyone who attends the event and our sponsors.

It is available in real time. To access the list please just log into your registration details or use the QR code

on right of the agenda card which is provided on the day of the event.

You will not be included in this list if you have opted out and you can do this by logging into your registration

details. This list will not be sold or ever give out to third parties.

Can I have the speakers’ slides?

We cannot give out the slides from our speakers’ presentations as they are deleted immediately after each

event. If you require a particular set of slides, please approach the speaker. We will however have a meeting

report and you will be emailed when this report is published.

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Notepads and pens are provided in the delegate bags and at the registration desk.

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Is there WIFI?

Yes, please ask registration for log in details.

Can I have a CPD/ CME certificate?

CPD certificates will be available in the exhibition hall after lunch.

Please remember that EuroSciCon is a small independent company with no subsidies from society

memberships or academic rates for venues. We try to be as reasonably priced as possible and our delegate

rates are substantially lower than comparable commercial meeting organisations

Personal belongings

Please take care of all your personal belonging as Euroscicon cannot be held responsible if an item goes

missing from the lecture theatre or the exhibition hall.

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EuroSciCon Ltd. Registered in England and Wales, Company number: 4326921, Trading Address: Euroscicon Ltd, Highstone House, 165 High Street, Barnet, Herts. EN5 5SU, UK. Registered Office: 47 High Street, Barnet, Herts, EN5 5UW, UK